US20190023716A1 - Fumagillol spirocyclic compounds and fused bicyclic compounds and methods of making and using same - Google Patents

Fumagillol spirocyclic compounds and fused bicyclic compounds and methods of making and using same Download PDF

Info

Publication number
US20190023716A1
US20190023716A1 US15/922,378 US201815922378A US2019023716A1 US 20190023716 A1 US20190023716 A1 US 20190023716A1 US 201815922378 A US201815922378 A US 201815922378A US 2019023716 A1 US2019023716 A1 US 2019023716A1
Authority
US
United States
Prior art keywords
yl
3r
1h
methyl
6r
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
US15/922,378
Inventor
Robert Zahler
Zhenwei Cai
Zhixing Wu
James E. Vath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zafgen Inc
Original Assignee
Zafgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CN201510490559.1 priority Critical
Priority to CN201510490559.1A priority patent/CN106432255A/en
Priority to US201562210102P priority
Priority to PCT/US2016/046515 priority patent/WO2017027687A1/en
Priority to US15/827,074 priority patent/US9944613B2/en
Application filed by Zafgen Inc filed Critical Zafgen Inc
Priority to US15/922,378 priority patent/US20190023716A1/en
Publication of US20190023716A1 publication Critical patent/US20190023716A1/en
Application status is Pending legal-status Critical

Links