US20160194340A1 - Arginase inhibitors and methods of use - Google Patents

Arginase inhibitors and methods of use Download PDF

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Publication number
US20160194340A1
US20160194340A1 US14/959,765 US201514959765A US2016194340A1 US 20160194340 A1 US20160194340 A1 US 20160194340A1 US 201514959765 A US201514959765 A US 201514959765A US 2016194340 A1 US2016194340 A1 US 2016194340A1
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US
United States
Prior art keywords
amino
compound
borono
alkyl
hexanoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
US14/959,765
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US10118936B2 (en
Inventor
David W. Christianson
Bruce Edward Tomczuk
Richard Scott Pottorf
Andrew Vargha Colasanti
Gary Lee Olson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
University of Pennsylvania
Original Assignee
AstraZeneca AB
University of Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority to US14727009P priority Critical
Priority to US12/693,863 priority patent/US20100189644A1/en
Application filed by AstraZeneca AB, University of Pennsylvania filed Critical AstraZeneca AB
Priority to US14/959,765 priority patent/US10118936B2/en
Publication of US20160194340A1 publication Critical patent/US20160194340A1/en
Application granted granted Critical
Publication of US10118936B2 publication Critical patent/US10118936B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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