US20150209525A1 - Injection devices - Google Patents

Injection devices Download PDF

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Publication number
US20150209525A1
US20150209525A1 US14/681,539 US201514681539A US2015209525A1 US 20150209525 A1 US20150209525 A1 US 20150209525A1 US 201514681539 A US201514681539 A US 201514681539A US 2015209525 A1 US2015209525 A1 US 2015209525A1
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US
United States
Prior art keywords
syringe
forward
housing
injection device
device according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US14/681,539
Inventor
Stephen Bicknell
Mark Eaton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Owen Mumford Ltd
Original Assignee
Owen Mumford Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB0715623A priority Critical patent/GB2452030A/en
Priority to GB0715623.5 priority
Priority to PCT/GB2008/002741 priority patent/WO2009022132A2/en
Priority to US67291410A priority
Application filed by Owen Mumford Ltd filed Critical Owen Mumford Ltd
Priority to US14/681,539 priority patent/US20150209525A1/en
Assigned to OWEN MUMFORD LIMITED reassignment OWEN MUMFORD LIMITED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BICKNELL, STEPHEN, EATON, MARK
Publication of US20150209525A1 publication Critical patent/US20150209525A1/en
Application status is Abandoned legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/3243Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3245Constructional features thereof, e.g. to improve manipulation or functioning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033Spring-loaded one-shot injectors with or without automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps
    • A61M5/3204Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/3243Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006Having specific accessories
    • A61M2005/202Having specific accessories cocking means, e.g. to bias the main drive spring of an injector
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206With automatic needle insertion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2073Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M2005/3142Modular constructions, e.g. supplied in separate pieces to be assembled by end-user
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/3243Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3245Constructional features thereof, e.g. to improve manipulation or functioning
    • A61M2005/3246Constructional features thereof, e.g. to improve manipulation or functioning being squeezably deformable for locking or unlocking purposes, e.g. with elliptical cross-section
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321Means for protection against accidental injuries by used needles
    • A61M5/3243Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/3245Constructional features thereof, e.g. to improve manipulation or functioning
    • A61M2005/3247Means to impede repositioning of protection sleeve from needle covering to needle uncovering position

Abstract

An injection device includes a forward housing, a drive housing that has a forward end configured to be attached to and detached from a rear end of the forward housing, a syringe holder mounted within the forward housing for longitudinal movement with respect to the forward housing, and a syringe with a needle that is mounted in the syringe holder. The drive housing includes a drive mechanism, and the syringe holder includes detent means for engaging the syringe to prevent or limit relative axial movement of the syringe relative to the syringe holder.

Description

  • This invention relates to injection devices and in particular, but not exclusively, to automatic injector devices having a mechanism which moves a syringe within the device forwardly so that the needle tip projects from the device and then delivers the dose through the needle.
  • Many automatic injectors are designed to deliver one dose and then to be discarded after use. Although often the cost of the drug dispensed is much greater than the cost of the injector device, there is a concern to reduce the cost of the drug delivery system and also an environmental desire to reuse components where necessary. We have therefore designed an automatic injector device in which the drive mechanism may be reused and provided as a separate module which is screwed or otherwise coupled to a housing containing the syringe, so that the driver module can be reused many times. However the design of such a device means that internal access to the forward portion is possible and so it is desirable to provide some means of preventing movement of the syringe in the housing when separate from the drive module, so as to prevent the possibility of a syringe being pushed forwardly in the housing to expose the needle either before or after use. In other, manually operated devices, it is also desirable to disable or make safe an injection device before and after use.
  • Accordingly, in one aspect, this invention provides an injection device comprising:
      • a main housing portion;
      • a syringe having a needle, said syringe being mounted in said housing portion for movement between a rearward position in which said needle is shrouded by a forward part of said housing portion, and a forward position in which said needle projects forwardly of said housing for delivery of a dose;
      • locking means for locking said syringe in a rearward position, said locking means being releasable to allow forward movement of the syringe, and
      • latch means operable to latch the released syringe in a rearward position after delivery of a dose.
  • The syringe is conveniently held in a syringe holder that cooperates with said locking means and said latching means.
  • Preferably said locking means and said latching means are defined by a common moveable locking/latching element moveable between:
      • a locking/latching position in which it (i) prevents movement of said syringe forwardly from a rearward position, and (ii) latches said syringe against forward movement when returning from a forward position towards a rearward position,
      • and
      • an unlocked position in which the syringe is allowed to move forward.
  • The latching/locking element may comprise at least one latch portion moveable generally transversely relative to the syringe between said locking/latching position and said unlocked position. Each latch portion may be carried on a respective finger moveable transversely between said locking/latching position and said unlocked position. Thus a plurality of latching portions may be provided on arcuate wall portions of a generally cylindrical resiliently expandable locking sleeve.
  • Said locking sleeve is preferably releasable by axial engagement and shifting of said wall portions by a release ring portion.
  • Where the device includes a driver mechanism disposed in a drive housing having a forward end for releasable engagement with the rear end of said housing portion, said locking means and said latching means may be designed to be released upon a predetermined extent of engagement between said drive housing and said main housing portion.
  • Where said main housing portion and said drive housing portion are threadedly engageable said drive portion may carry a release ring portion for engaging said locking sleeve.
  • Whilst the invention has been described above, it extends to any inventive combination of the features set out above, or in the following description.
  • The invention may be performed in various ways, and an embodiment thereof will be described by way of example only, reference being made to the accompanying drawings in which:
  • FIG. 1 is a side view of an automatic injector with a separate drive module screwed onto the rear end of a forward housing containing the syringe;
  • FIG. 2 is a longitudinal sectional view taken on lines:II-II of FIG. 1;
  • FIG. 3 is a detailed view on the latching sleeve;
  • FIG. 4 is an isometric view looking rearwardly on the drive module;
  • FIGS. 5( a) and (b) are enlarged views showing the latch sleeve in its latching position and its open position respectively.
  • FIG. 6 is a view similar to FIG. 1 but showing the device when fired, and
  • FIG. 7 is a section view showing the forward portion unscrewed from the drive module after use.
  • Referring to the drawings, the embodiment of injection device disclosed therein is an automatic injector comprising a drive module 10 which can be screwed into the back of a syringe housing 12 to prepare the injector ready for use. The device has a firing button 14 at its rear end and the front end of the syringe housing is initially covered by a cap 16. The drive module 10 slideably supports a drive plunger 18 which is urged forwardly by means of a drive spring 20. At the rear end, the plunger 18 is formed with a split arrowhead configuration 22 which enables the plunger to latch in a cocked position behind an internal wall in the module casing.
  • In order to fire the device, the firing button 14 is rotated from a safe to an armed position and then pushed forwardly so as to squeeze the arrowheads together releasing the plunger for forward movement under the influence of the drive spring 20. Forward movement of the plunger is limited by an annular rib 26 which co-operates with an end wall in the drive housing 10. The forward end of the drive plunger 18 is of reduced diameter to fit within a bung 28 of the syringe 30. At its front end, drive module 10 has a female threaded portion 32 threadable onto a corresponding male threaded portion 34 on the rear of the syringe housing 12.
  • The syringe housing 12 slideably receives a syringe holder 36 mounted for slideable movement within the housing 12, urged rearwardly by a compression spring 38, the rearward movement being constrained by a shoulder on a snap fit annulus 40 on the syringe holder. The syringe 30 is concentrically held within the syringe holder 36 by snap detent features 37, that clip behind the skirt at the rear end of the syringe, and moves axially therewith between the rearward position shown in FIG. 2 and the forward position shown in FIG. 6.
  • Concentrically surrounding the syringe holder 36 and the spring 38 is a cylindrical latching she 42 whose form can be seen more clearly in FIG. 3. The latching shell 42 has slots dividing its cylindrical surface into six arcuate resiliently deformable arms 44, each having an internally directed barb 46 short of the end thereof. The free ends of the resilient arms 44 are chamfered as shown at 48.
  • The latching sleeve 42 is acted on by a release ring portion 50 on the front end of the drive module so that, as the drive module is screwed into the back of the syringe housing, the release ring portion 50 engages the chamfered portions 48 to splay out the resilient arms 44 to lift them from the locking position, shown in FIG. 5 where they abut and block the path of movement of a shoulder 52 on the syringe holder 36, to the splayed position shown in FIG. 5, where the arms are deflected outwardly so that the barbs 46 are clear of the path of movement of the syringe holder 36.
  • The co-operation of the release ring portion 50 and the latching sleeve 42 means that, when the syringe housing 12 is separated from a drive module 10, the sleeve is in its relaxed position in which the barbs 46 block movement of the syringe carrier 36. Also, after use, when the drive module 10 has been unscrewed from the syringe housing the barbs again return to their locking position to latch and prevent forward movement of the used syringe as it returns to its rear position.
  • The cap 16 may have inwardly directed fingers or a suitable engagement surface (not shown) which grips a sheath (not shown) initially covering the syringe needle, or otherwise engages the sheath so that removal of the cap from the device also pulls the sheath off the needle.
  • In use, the drive module is cocked and the cap is removed from the front end of a syringe housing. The drive module is then screwed into the back of the syringe housing. Towards the end of the threaded engagement the release ring portion 50 engages the chamfers 48 thus splaying the arms of the latching sleeve to release the syringe holder 36 for movement.
  • The device is then offered up to the user's skin. The button 14 is turned to the armed position and pressed to release the plunger. The plunger shoots forward driving the syringe 30 forwardly with it due to the incompressible nature of the syringe contents so that the needle projects beyond the forward end of the housing. The syringe is arrested and the spring 38 is fully compressed and thereafter the plunger drives the bung 28 forwardly to expel the dose. At this stage the components are in the configuration shown in FIG. 6.
  • The user then unscrews the drive module 10 from the syringe housing 12 and the release ring 50 is drawn out of engagement with the latching sleeve so that it returns to the position shown in FIG. 5. The syringe carrier is urged rearwardly by the spring 38 as the drive module is unscrewed and, when the parts separate and the drive module 10 is pulled away from the forward housing, the syringe carrier snaps past the barbs 46 so that it is locked in its rearward position.

Claims (11)

1. An injection device comprising,
a forward housing;
a drive housing having a forward end configured to be attached to and detached from a rear end of the forward housing, the drive housing including a drive mechanism;
a syringe holder mounted within said forward housing for longitudinal movement with respect to said forward housing; and
a syringe having a needle, wherein said syringe is mounted in said syringe holder,
said syringe holder including detent means for engaging said syringe to prevent or limit relative axial movement of the syringe relative to the syringe holder.
2. An injection device according to claim 1, wherein said detent means are provided at a rear end of the syringe holder.
3. An injection device according to claim 1, wherein said syringe includes a rear end having a radially extending skirt.
4. An injection device according to claim 3, wherein said detent means include snap detent features which engage a rear surface of the syringe skirt when the syringe is mounted within said syringe holder.
5. An injection device according to claim 1, wherein said syringe holder is slideably mounted in said forward housing.
6. An injection device according to claim 5, wherein said syringe holder is provided with at least one engagement feature on its outer surface which engages said forward housing to limit rearward movement of the syringe holder.
7. An injection device according to claim 5, wherein said the syringe holder is provided with a snap fit annulus having a rearward facing shoulder, wherein the rearward facing shoulder engages with said a forward facing surface provided on an inner surface of said forward housing to limit rearward movement of the syringe holder.
8. An injection device according to claim 1, wherein said syringe being mounted in said forward housing portion for movement between a rearward position in which said needle is shrouded by a forward part of said housing portion, and a forward position in which said needle projects forwardly of said housing for delivery of a dose; and wherein the device is further provided with
a locking arrangement for locking said syringe in a rearward position, and being releasable to allow forward movement of the syringe; and
a latch arrangement operable to latch the released syringe as it returns to a rearward position after delivery of a dose.
9. An injection device according to claim 8, wherein said syringe is held in a syringe holder and said locking arrangement and said latching arrangement cooperate with said syringe holder to lock and latch said syringe respectively.
10. An injection device according to claim 9, wherein said locking arrangement and said latching arrangement are defined by a common moveable locking/latching element moveable between:
a locking/latching position in which it
i) prevents movement of said syringe forwardly from a rearward position, and
ii) latches said syringe when returning from a forward position towards a rearward position; and
an unlocked position in which the syringe is allowed to move forward.
11. An injection device according to claim 10, wherein said latching/locking element comprises at least one latch portion moveable generally transversely relative to the syringe between said locking/latching position and said unlocked position
US14/681,539 2007-08-10 2015-04-08 Injection devices Abandoned US20150209525A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB0715623A GB2452030A (en) 2007-08-10 2007-08-10 Injection devices
GB0715623.5 2007-08-10
PCT/GB2008/002741 WO2009022132A2 (en) 2007-08-10 2008-08-11 Injection devices
US67291410A true 2010-04-27 2010-04-27
US14/681,539 US20150209525A1 (en) 2007-08-10 2015-04-08 Injection devices

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14/681,539 US20150209525A1 (en) 2007-08-10 2015-04-08 Injection devices

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
PCT/GB2008/002741 Continuation WO2009022132A2 (en) 2007-08-10 2008-08-11 Injection devices
US67291410A Continuation 2010-04-27 2010-04-27

Publications (1)

Publication Number Publication Date
US20150209525A1 true US20150209525A1 (en) 2015-07-30

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
US12/672,914 Active 2030-02-11 US9022989B2 (en) 2007-08-10 2008-08-11 Injection devices
US14/681,539 Abandoned US20150209525A1 (en) 2007-08-10 2015-04-08 Injection devices

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US12/672,914 Active 2030-02-11 US9022989B2 (en) 2007-08-10 2008-08-11 Injection devices

Country Status (6)

Country Link
US (2) US9022989B2 (en)
EP (1) EP2185227B1 (en)
JP (2) JP2010535564A (en)
CN (1) CN101784297B (en)
GB (1) GB2452030A (en)
WO (1) WO2009022132A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150179994A1 (en) * 2012-06-13 2015-06-25 Somfy Sas Element for mounting a battery in a winding tube of a home-automation screen

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60323729D1 (en) 2002-02-11 2008-11-06 Antares Pharma Inc Intradermal injection device
CA2595730C (en) 2005-01-24 2014-10-07 Antares Pharma, Inc. Prefilled needle assisted syringe jet injector
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US8251947B2 (en) 2006-05-03 2012-08-28 Antares Pharma, Inc. Two-stage reconstituting injector
GB2452030A (en) * 2007-08-10 2009-02-25 Owen Mumford Ltd Injection devices
EP2990067B1 (en) 2008-03-10 2019-09-04 Antares Pharma, Inc. Injector safety device
GB0806814D0 (en) 2008-04-15 2008-05-14 Medical House Plc The Improved autoinjector
AU2009279719B2 (en) 2008-08-05 2015-07-23 Antares Pharma, Inc. Multiple dosage injector
GB0823693D0 (en) 2008-12-31 2009-02-04 Owen Mumford Ltd Autoinjector
AU2010226442A1 (en) 2009-03-20 2011-10-13 Antares Pharma, Inc. Hazardous agent injection system
AU2014200306B2 (en) * 2010-05-20 2015-04-02 Becton, Dickinson And Company Drug delivery device
GB2486681B (en) * 2010-12-22 2017-02-01 Owen Mumford Ltd Autoinjectors
FR2971424B1 (en) * 2011-02-14 2013-11-29 Marc Brunel Safety syringe
GB2488579A (en) * 2011-03-02 2012-09-05 Owen Mumford Ltd Autoinjector with "injection complete" indicator
EP2514450A1 (en) * 2011-04-21 2012-10-24 Sanofi-Aventis Deutschland GmbH Medicated module with automatic reservoir engagement and magnetic lock mechanism
WO2012143438A1 (en) * 2011-04-21 2012-10-26 Sanofi-Aventis Deutschland Gmbh Module assembly with locking strut
CA2828438A1 (en) 2011-04-21 2012-10-26 Sanofi-Aventis Deutschland Gmbh Medicated module with lock feature
JP2014514098A (en) * 2011-04-21 2014-06-19 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Medicinal module with automatic reservoir engagement and trigger lock mechanism
CA2828437A1 (en) 2011-04-21 2012-10-26 Sanofi-Aventis Deutschland Gmbh Medicated module with lock ring
GB2490721B (en) * 2011-05-12 2017-03-01 Owen Mumford Ltd Injection devices
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
WO2013032779A2 (en) * 2011-08-26 2013-03-07 Eli Lilly And Company Refill module for an injection device
EP2601990A1 (en) * 2011-12-08 2013-06-12 Sanofi-Aventis Deutschland GmbH Syringe carrier
US9486583B2 (en) 2012-03-06 2016-11-08 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
EP2833944A4 (en) 2012-04-06 2016-05-25 Antares Pharma Inc Needle assisted jet injection administration of testosterone compositions
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
WO2014061151A1 (en) * 2012-10-19 2014-04-24 テルモ株式会社 Medication delivery device
EP2953667B1 (en) 2013-02-11 2019-10-23 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
EP2968792B1 (en) 2013-03-11 2019-05-15 Antares Pharma, Inc. Dosage injector with pinion system
WO2014165136A1 (en) 2013-03-12 2014-10-09 Antares Pharma, Inc. Constant volume prefilled syringes and kits thereof
AT514484B1 (en) * 2013-06-24 2015-05-15 Pharma Consult Gmbh Activator for an auto-injector
US9199033B1 (en) 2014-10-28 2015-12-01 Bayer Healthcare Llc Self-orienting syringe and syringe interface
NO2689315T3 (en) 2014-10-28 2018-04-14
BR112017007035A2 (en) 2014-11-18 2017-12-12 Lilly Co Eli thermal locking mechanism for a drug delivery device
US20170100542A1 (en) * 2015-10-09 2017-04-13 Medimop Medical Projects Ltd. Angled syringe patch injector
GB2560554A (en) * 2017-03-15 2018-09-19 Owen Mumford Ltd Injection device with gap reduction mechanism
JP2019136293A (en) * 2018-02-09 2019-08-22 ニプロ株式会社 Medical solution injection device
US20190351144A1 (en) * 2018-05-17 2019-11-21 Certa Dose, Inc. Syringe holder for medication dosing

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099503A (en) * 1995-04-18 2000-08-08 Tebro Reloadable auto-injector
US6544234B1 (en) * 1998-01-24 2003-04-08 B D Medico S.A.R.L. Injection device
US9022989B2 (en) * 2007-08-10 2015-05-05 Owen Mumford Limited Injection devices

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5176643A (en) 1991-04-29 1993-01-05 George C. Kramer System and method for rapid vascular drug delivery
GB9111600D0 (en) * 1991-05-30 1991-07-24 Owen Mumford Ltd Improvements relating to injection devices
DE69426390D1 (en) * 1993-07-31 2001-01-11 Weston Medical Ltd Needleless injector
US5478316A (en) * 1994-02-02 1995-12-26 Becton, Dickinson And Company Automatic self-injection device
US5843036A (en) * 1996-08-23 1998-12-01 Becton Dickinson And Company Non-dosing cartridge for an injection device
DK1003580T3 (en) * 1997-08-21 2004-02-23 Ares Trading Sa injection device
FR2774294B1 (en) * 1998-02-04 2000-04-14 Marc Brunel An automatic injection of a dose of product medicated
US6613022B1 (en) 2000-05-05 2003-09-02 Safety Syringes, Inc. Passive needle guard for syringes
US9486581B2 (en) 2002-09-11 2016-11-08 Becton, Dickinson And Company Injector device with force lock-out and injection rate limiting mechanisms
FR2832932A1 (en) * 2001-11-30 2003-06-06 Endos Pharma Safety device for single-use injection syringe
US20030105430A1 (en) * 2001-11-30 2003-06-05 Elan Pharma International Limited Wil House Automatic injector
AU2003217404A1 (en) * 2002-02-15 2003-09-09 Antares Pharma, Inc. Injector with bypass channel
US6979316B1 (en) * 2002-05-23 2005-12-27 Seedlings Life Science Ventures Llc Apparatus and method for rapid auto-injection of medication
US7167528B2 (en) 2002-06-11 2007-01-23 General Instrument Corporation Modulation system for modulating data onto a carrier signal with offsets to compensate for doppler effect and allow a frequency synthesizing system to make steps equal to channel bandwidth
GB0224505D0 (en) 2002-10-22 2002-11-27 Medical House The Plc Needles injection device
WO2004069302A2 (en) * 2003-01-30 2004-08-19 Becton, Dickinson And Company Holder with safety shield for a drug delivery device
US20050027255A1 (en) * 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
IL157984A (en) * 2003-09-17 2015-02-26 Dali Medical Devices Ltd Autoneedle
US7101351B2 (en) * 2003-11-03 2006-09-05 Becton, Dickinson And Company Safety device for a syringe
US7468054B2 (en) * 2003-11-03 2008-12-23 Becton, Dickinson And Company Safety shield system for a syringe
GB2414406B (en) * 2004-05-28 2009-03-18 Cilag Ag Int Injection device
GB2414404B (en) * 2004-05-28 2009-06-03 Cilag Ag Int Injection device
FR2874505B1 (en) * 2004-08-27 2007-06-08 Sedat Sa Injection device comprising a syringe
US20060069350A1 (en) * 2004-09-30 2006-03-30 Buenger David R Medical syringe injector pen
US20070265568A1 (en) * 2004-11-04 2007-11-15 Izrail Tsals Automatic Injector

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6099503A (en) * 1995-04-18 2000-08-08 Tebro Reloadable auto-injector
US6544234B1 (en) * 1998-01-24 2003-04-08 B D Medico S.A.R.L. Injection device
US9022989B2 (en) * 2007-08-10 2015-05-05 Owen Mumford Limited Injection devices

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150179994A1 (en) * 2012-06-13 2015-06-25 Somfy Sas Element for mounting a battery in a winding tube of a home-automation screen
US9722220B2 (en) * 2012-06-13 2017-08-01 Somfy Sas Element for mounting a battery in a winding tube of a home-automation screen

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GB2452030A (en) 2009-02-25
JP2010535564A (en) 2010-11-25
EP2185227A2 (en) 2010-05-19
WO2009022132A2 (en) 2009-02-19
CN101784297B (en) 2013-08-28
JP5698797B2 (en) 2015-04-08
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CN101784297A (en) 2010-07-21
EP2185227B1 (en) 2014-03-26

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