US20130274600A1 - Devices and Method for Maxillary Sinus Lavage - Google Patents

Devices and Method for Maxillary Sinus Lavage Download PDF

Info

Publication number
US20130274600A1
US20130274600A1 US13/800,163 US201313800163A US2013274600A1 US 20130274600 A1 US20130274600 A1 US 20130274600A1 US 201313800163 A US201313800163 A US 201313800163A US 2013274600 A1 US2013274600 A1 US 2013274600A1
Authority
US
United States
Prior art keywords
catheter
distal
irrigation
maxillary sinus
elongate shaft
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US13/800,163
Inventor
Thomas R. Jenkins
Jessica Liberatore
Sandra W. Ruggles
Jessica K. Chan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Acclarent Inc
Original Assignee
Acclarent Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201261623730P priority Critical
Priority to US201261675595P priority
Application filed by Acclarent Inc filed Critical Acclarent Inc
Priority to US13/800,163 priority patent/US20130274600A1/en
Assigned to ACCLARENT, INC. reassignment ACCLARENT, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: CHAN, JESSICA KRISTEN, RUGGLES, SANDRA WAUGH, JENKINS, THOMAS ROY, LIBERATORE, JESSICA
Publication of US20130274600A1 publication Critical patent/US20130274600A1/en
Application status is Abandoned legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0133Tip steering devices
    • A61M25/0147Tip steering devices with movable mechanical means, e.g. pull wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/07Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0133Tip steering devices
    • A61M25/0152Tip steering devices with pre-shaped mechanisms, e.g. pre-shaped stylets or pre-shaped outer tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/02Enemata; Irrigators
    • A61M3/0279Cannula; Nozzles; Tips; their connection means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/233Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the nose, i.e. nasoscopes, e.g. testing of patency of Eustachian tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M2025/0004Catheters; Hollow probes having two or more concentrically arranged tubes for forming a concentric catheter system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M2025/0004Catheters; Hollow probes having two or more concentrically arranged tubes for forming a concentric catheter system
    • A61M2025/0006Catheters; Hollow probes having two or more concentrically arranged tubes for forming a concentric catheter system which can be secured against axial movement, e.g. by using a locking cuff
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M2025/0175Introducing, guiding, advancing, emplacing or holding catheters having telescopic features, interengaging nestable members movable in relations to one another
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/06Head
    • A61M2210/0681Sinus (maxillaris)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0041Catheters; Hollow probes characterised by the form of the tubing pre-formed, e.g. specially adapted to fit with the anatomy of body channels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/0105Steering means as part of the catheter or advancing means; Markers for positioning
    • A61M25/0113Mechanical advancing means, e.g. catheter dispensers

Abstract

A lavage catheter for the treatment of a maxillary sinus is described. The catheter comprises a proximal portion and a distal portion. The distal portion comprises an irrigation tip. The irrigation tip has a tip opening through which fluid may be delivered by one handed operation of the catheter. A method for lavaging the maxillary sinus includes inserting the lavage catheter into a patient's anatomy and advancing the irrigation tip into the maxillary sinus using one hand.

Description

    FIELD OF THE INVENTION
  • The present invention relates, in general, to medical devices and, in particular, to medical devices and related methods for the treatment of sinus conditions.
  • BACKGROUND OF THE INVENTION
  • The paranasal sinuses are hollow cavities in the skull connected by small openings, known as ostia, to the nasal canal. Each ostium between a paranasal sinus and the nasal cavity is formed by a bone covered by a layer of mucosal tissue. Normally, air passes into and out of the paranasal sinuses through the ostia. Also, mucus is continually formed by the mucosal lining of the sinuses and drains through the ostia and into the nasal canal.
  • Sinusitis is a general term that refers to inflammation in one or more of the paranasal sinuses. Acute sinusitis can be associated with upper respiratory infections or allergic conditions, which may cause tissue swelling and temporarily impede normal trans-ostial drainage and ventilation of the sinuses, thereby resulting in some collection of mucus and possibly infection within the sinus cavities. Chronic sinusitis is a long term condition characterized by persistent narrowing or blockage of one or more sinus ostia, resulting in chronic infection and inflammation of the sinuses. Chronic sinusitis is often associated with longstanding respiratory allergies, nasal polyps, hypertrophic nasal turbinates and/or deviated internasal septum. While acute sinusitis is typically caused by infection with a single pathogen (e.g., one type of bacteria, one type of virus, one type of fungus, etc.), chronic sinusitis is often associated with multiple pathogen infections (e.g., more than one type of bacteria or more than one genus of micro-organism).
  • Chronic sinusitis, if left untreated, can result in irreparable damage to the tissues and/or bony structures of the paranasal anatomy. The initial treatment of chronic sinusitis usually involves the use of drugs such as decongestants, steroid nasal sprays and antibiotics (if the infection is bacterial). In cases where drug treatment alone fails to provide permanent relief, surgical intervention may be indicated.
  • The most common surgical procedure for treating chronic sinusitis is functional endoscopic sinus surgery (FESS). FESS is commonly performed using an endoscope and various rigid instruments inserted through the patient's nostril. The endoscope is used to visualize the positioning and use of various rigid instruments used for removing tissue from the nasal cavity and sinus ostia in an attempt to improve sinus drainage.
  • A technique known as the Balloon Sinuplasty™ procedure and a system for performing the procedure has been developed by Acclarent Inc, of Menlo Park, Calif. for treatment of sinusitis. A number of US patents and patent applications including U.S. Pat. Nos. 7,645,272, 7,654,997, and 7,803,150 describe various embodiments of the Balloon Sinuplasty™ procedure as well as various devices useable in the performance of such procedure. In the Balloon Sinuplasty™ procedure, a guide catheter is inserted into the nose and positioned within or adjacent to the ostium of the affected paranasal sinus. A guidewire is then advanced through the guide catheter and into the affected paranasal sinus. Thereafter, a dilation catheter having an expandable dilator (e.g. an inflatable balloon) is advanced over the guidewire to a position where the dilator is positioned within the ostium of the affected paranasal sinus. The dilator is then expanded, causing dilation of the ostium and remodelling of bone adjacent to the ostium, without required incision of the mucosa or removal of any bone. The catheters and guidewire are then removed and the dilated ostium allows for improved drainage from and ventilation of the affected paranasal sinus.
  • Before or after performing a FESS or Balloon Sinuplasty™ procedure, it may be useful or necessary to irrigate the paranasal sinus. A device described in US 2008/0183128 may be used for irrigating a paranasal sinus. The irrigation catheter may be advanced through a guide catheter and into an ostium or the sinus for purposes of, for example irrigation, suctioning, substance delivery and culture retrieval.
  • There is a continuing need for improved methods and devices for treating the paranasal sinus. Although the irrigation catheter described above is easy to use, it would be useful to provide an improved catheter for irrigating the maxillary sinuses.
  • SUMMARY OF THE INVENTION
  • In a first aspect, the invention is a catheter for the lavage of a maxillary sinus comprising a distal portion having an elongate shaft with a bend angle of between about 90 degrees and 140 degrees. The lavage catheter distal portion further has a distal irrigation tube that is in coaxial arrangement with the elongate shaft. An actuator that is located between a distal hub and a proximal hub is used for advancing the distal irrigation tube into the maxillary sinus. The lavage catheter further includes a proximal portion with an irrigation luer and irrigation tubing.
  • In one embodiment of the lavage catheter, the irrigation tip has a distal tip opening.
  • In another embodiment, the irrigation tip has and one or more radially facing openings.
  • In another embodiment the distal irrigation tube is a flexible material selected from the group consisting of nylon, polyethylene, polyether ether ketone or polyether block amides.
  • In a further embodiment, the distal irrigation tube is a polyether block amide.
  • In still another embodiment, the lavage catheter includes one or more direct visualization markers.
  • In another embodiment, the lavage catheter includes one or more radiographic markers.
  • In a further embodiment, the distal irrigation tube surrounds the elongate shaft.
  • In yet a further embodiment, the distal irrigation tube is surrounded by the elongate shaft.
  • In still another embodiment, the lavage catheter comprises an illuminating fiber.
  • In another embodiment, the distal irrigation tip has a tapered configuration.
  • In another aspect, the invention is a catheter for the lavage of a maxillary sinus. The catheter includes a distal portion and a proximal portion. The distal portion in includes an elongate shaft with a bend angle of between about 90 degrees and 140 degrees, a distal irrigation tube in coaxial arrangement with the elongate shaft, and a handle with an actuator. The proximal portion of the catheter has an irrigation luer and irrigation tubing. The actuator is useful for advancing the distal irrigation tube into the maxillary sinus.
  • In one embodiment, the actuator has a light access port and the distal portion of the catheter includes an illuminating fiber.
  • In another aspect, the invention is a kit for the lavage of a maxillary sinus. The kit includes a catheter and an endoscope. The catheter includes a distal portion and a proximal portion. The distal portion has an elongate shaft with a bend angle of between about 90 degrees and 140 degrees, a distal irrigation tube coaxially arranged with the elongate shaft, an illuminating fiber, and a handle with an actuator. The actuator has a light access port for insertion of the endoscope. The actuator is useful for advancing the distal irrigation tube into the maxillary sinus. The proximal portion of the catheter has an irrigation luer and irrigation tubing,
  • In another aspect, the invention includes a method for lavaging a maxillary sinus. The method includes positioning a lavage catheter comprising a proximal portion, and a distal portion in the nasal anatomy. The distal portion comprises an irrigation tip. The method further includes connecting a fluid source to the irrigation catheter; with one hand, advancing the irrigation tip into the maxillary sinus; and delivering fluid to the maxillary sinus from the fluid source though the lavage catheter.
  • In a further embodiment, the method includes delivering the fluid at a flow rate of between 50 ml/min and 250 ml/min.
  • In yet another embodiment, the delivered fluid is selected from the group consisting of water, saline, contrast agents, antimicrobial agents anti-inflammatory agents, decongestants , mucous thinning agents, anesthetic agents, analgesic agents, anti-allergenic agents, allergens, anti-proliferative agents, hemostatic agents, cytotoxic agents, and biological agents or combinations of any of the above.
  • In another aspect, the invention is directed to a kit for the lavage of a maxillary sinus. The kit comprises a maxillary lavage catheter and a illuminating fiber connector. The catheter comprises a distal portion and a proximal portion. The catheter distal portion comprises an elongate shaft with a bend angle of between about 90 degrees and 140 degrees, a distal irrigation tube in coaxial arrangement with said elongate shaft, an illuminating fiber, and a handle. The handle comprises an actuator. The catheter proximal portion comprises an irrigation luer and irrigation tubing. The actuator is useful for advancing the distal irrigation tube into the maxillary sinus. The illuminating fiber connector connects the illuminating fiber to a light source, wherein the illuminating fiber connector allows for rotation of the catheter while the catheter is connected to the light source.
  • In another aspect, the invention is directed to a kit for the lavage of a maxillary sinus. The kit comprises a catheter and fluid delivery system. The catheter comprises a distal portion and a proximal portion. The distal portion comprises an elongate shaft with a bend angle of between about 90 degrees and 140 degrees, a distal irrigation tube in coaxial arrangement with the elongate shaft, an illuminating fiber, and a handle comprising an actuator. The proximal portion comprises an irrigation luer and irrigation tubing. The actuator is useful for advancing the distal irrigation tube into the maxillary sinus. The fluid delivery system provides for continuous fluid delivery to the catheter.
  • In a further embodiment, the fluid delivery system comprises a syringe, a fluid reservoir, a first one-way valve for directing fluid from the syringe into the catheter when pressure is applied to the syringe and a second one-way valve for directing fluid from the fluid reservoir into the catheter when pressure is released from the syringe.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is a side view of a medical device according to an embodiment of the present invention in a retracted configuration.
  • FIG. 2 is a side view of the medical device of FIG. 1 in an extended configuration.
  • FIG. 3 is a side view of a further embodiment of the medical device according to the invention.
  • FIG. 4 is an enlarged view of the distal portion of the medical device of FIG. 3 in an extended configuration.
  • FIG. 5 is a side view of yet another embodiment of the medical device according to the invention.
  • FIG. 6 is an enlarged view of the distal end of the medical device of FIG. 5 according to the invention.
  • FIG. 7 is a top view of still another embodiment of the medical device according to the invention.
  • FIG. 8 is a top view of yet another embodiment of the medical device according to the invention.
  • FIG. 9 is a schematic diagram of a continuous fluid injection system for use with the medical device according to the invention.
  • FIG. 10A is a light cable connector for use in connecting a light cable to the medical device according to the invention.
  • FIG. 10B is a side cut-away view of the light cable connector of FIG. 10A.
  • DETAILED DESCRIPTION
  • The following detailed description should be read with reference to the drawings, in which like elements in different drawings are identically numbered. The drawings, which are not necessarily to scale, depict exemplary embodiments for the purpose of explanation only and are not intended to limit the scope of the invention. The detailed description illustrates by way of example, not by way of limitation, the principles of the invention. This description will clearly enable one skilled in the art to make and use the invention, and describes several embodiments, adaptations, variations, alternatives and uses of the invention, including what is presently believed to be the best mode of carrying out the invention.
  • As used herein, the terms “about” or “approximately” for any numerical values or ranges indicate a suitable dimensional tolerance that allows the part or collection of components to function for its intended purpose as described herein.
  • Medical devices according to embodiments of the present invention are beneficial in that, for example, their configuration provides for a particularly efficient preparation and treatment of a patient's sinus and is mechanically simple. Moreover, the simplicity of the medical devices provides for them to be manufactured in a cost effective manner. In addition, the medical device according to embodiments of the present invention is sufficiently stiff that it can be beneficially employed to access sinus anatomy followed by a convenient suction and/or irrigation of the sinus.
  • FIG. 1 is a side view of a maxillary lavage catheter 100 according to an embodiment of the present invention. The maxillary lavage catheter 100 has a distal portion 102 and a proximal portion 106.
  • The distal portion 102 in the embodiment shown in FIG. 1 includes an elongate shaft 108 with sufficient stiffness to access the maxillary sinus that further includes a distal end 110 and a proximal end 112. The distal end 110 of the elongate shaft 108 has a bend angle that is optimal for access to the maxillary sinus such that it can be maneuvered to access behind the uncinate process. Accordingly, the bend angle is between about 90° and 140°, often between about 100° and 130° and often about 110° or about 120°. The elongate shaft may be of any material that will maintain its shape when inserted into the patient's anatomy including but not limited to a polymeric material selected from the group including but not limited to nylon, polycarbonate, and styrene, or a biocompatible metal including but not limited to stainless steel, but will often be a stainless steel hypotube that may or may not be coated or colored, often in black, white or blue. Alternatively, the elongate shaft 108 may be made of a malleable material including but not limited to annealed stainless steel that can be shaped appropriately for accessing the maxillary sinus.
  • The distal portion 102 of the maxillary lavage catheter 100 additionally includes a distal irrigation tube 114 that is in coaxial arrangement elongate shaft 108. In the embodiment shown in FIG. 1, the distal irrigation tube 114 surrounds the elongate shaft 108, but in an alternative embodiment, the distal irrigation tube 114 may be surrounded by the elongate shaft 108. The distal irrigation tube 114 may be of any flexible material that can be used to extend into the maxillary sinus as will be described further below, including but not limited to a flexible, biocompatible polymer material, such as nylon, polyethylene, polyether ether ketone (PEEK), or polyether block amides (e.g. Pebax for example) and that may be braided or not braided. In the embodiment shown in FIG. 1, the material is Pebax.
  • The distal end 110 of the distal irrigation tube 114 includes a soft, atraumatic tip 118. The soft atraumatic tip 118 may be of a low durometer pebax material and it may be of tapered construction for easy access into the maxillary sinus. The atraumatic tip 118 may further have one or more radially facing openings to facilitate irrigation, often one, two or three openings of between about 0.5 to about 1.5 mm, often between about 0.8 and 1.0 mm. The lavage catheter 100 is designed to irrigate the sinus through the atraumatic tip 118 at a flow rate of between about 50 ml/min and 250 ml/min and often between about 75 ml/min and 125 ml/min. The diameter of the opening 212 of the atraumatic tip is between about 0.5 mm and 1.5 mm, and is often between about 0.9 mm and 1.0 mm. Further, instead of delivering fluid, a vacuum may be applied and a culture may be obtained by suctioning through the atraumatic tip 118.
  • The distal portion 102 of the maxillary lavage catheter 100 additionally includes a proximal hub 132 and a distal hub 136. Between the proximal hub 132 and the distal hub 136 are stiffening elements 138 and 140, and an actuator 142. The actuator 142 has a proximal end 150 and a distal end 152. The proximal end 112 of the elongate shaft 108 extends through the proximal hub 132 and connects to the distal end 122 of the proximal irrigation tube 120. The proximal end 115 of the distal irrigation tube 114 is connected to the distal end 152 of the actuator 142. The stiffening elements 138 and 140 extend from the proximal end of the distal hub 136 through the actuator 142 to the distal end 160 or proximal hub 132. As shown in FIG. 1, when the proximal irrigation tube 120 is fully retracted, the proximal end 150 of actuator 142 is adjacent to the distal end 160 of the proximal hub 132.
  • The distal hub 136 and proximal hub 132 are configured for one-handed operation of the maxillary lavage catheter 100. The narrow portion 170 of the distal hub 136 may be for grasped while the ridge 172 on the actuator 142 is pushed toward the distal hub 136 with the thumb. Alternatively, the narrow portion 170 of the distal hub 136 is may be grasped by the thumb and one or more fingers while the ridge 172 on the actuator 142 can be drawn toward the distal hub 136 with one finger. In this way, as is shown in FIG. 2, the distal irrigation tube 114 is extended beyond the distal end 110 of the elongate shaft 108 and into the maxillary sinus. Similarly, removal from the nasal anatomy can be effected by the thumb or single finger of the physician user as pressure is applied on the ridge 172, pushing it away from the nasal anatomy, retracting the distal irrigation tube 114 and the removing the maxillary lavage catheter from the nasal anatomy. In an alternative embodiment, a spring may be included to automatically retract the distal irrigation tube 114 following irrigation of the maxillary sinus. Although the embodiments shown in FIGS. 1 and 2 shown the distal irrigation tube 114 coaxially surrounding the elongate shaft 108, contemplated herein is also a configuration where in the irrigation tube elongate shaft 108 coaxially surrounds the distal irrigation tube 114.
  • Another embodiment of the maxillary lavage catheter 800 according to the invention is shown in FIG. 8 having a distal portion 802 and a proximal portion 804 and a light cable connector 806. In this embodiment, a handle 808 and an actuator 810 are included on the distal portion 802 of the catheter 800. The handle has an opening 812 with a distal end 814 and a proximal end 816. When the actuator 810 is seated against the proximal end 816 of the opening 812, the irrigation tubing (not shown, see FIG. 3) of the maxillary lavage catheter 800 is contained within the maxillary lavage catheter. When the actuator 810 is advanced in a one-handed fashion, with a single finger or thumb, and seated against the distal end 814 of the opening 800, the irrigation tubing (not shown, see FIG. 4) is extended out of the distal end 818 of the maxillary lavage catheter 800.
  • As shown in FIG. 1, the proximal portion 106 of the maxillary lavage catheter 100 includes a proximal irrigation tube 120 with a proximal end 124 and a distal end 122. The proximal end 124 of the proximal irrigation tube 120 contains a luer connector 126 and the distal end connects to the proximal end 112 of the elongate shaft 108. The luer connector 126 connects the proximal end 124 of the proximal irrigation tube 120 with a source of irrigation for lavage of the maxillary sinus. A syringe (e.g., having a volume of about 10 cc to about 60 cc, for example) may be connected to luer connector 126. The syringe may be used to drive the irrigation fluid out of the atraumatic tip 118 by hand pressure by the operator on a hand pushable plunger of the syringe. Fluid pressures of about 4 to about 6 pounds per square inch (psi) are typically generated when using a 60 cc syringe, and pressures of about 15 to about 25 psi can be generated using a 10 cc syringe with flow rates of between about 50 ml/min and 250 ml/min, and often between about 75 ml/min and 125 ml/min. Alternatively, the luer connector 126 may be connected to a vacuum source to apply suction to the maxillary sinus. Further, a pulsation device may be included to achieve pulsatile delivery of the irrigation fluid. An in-line valve assembly may be included between the fluid source, in this case a syringe, and the catheter, in this case the luer connector 126. In a particular embodiment, to maximize irrigation efficiency, the valve assembly prevents flow when the applied force is low and allows fluid to pass one the pressure reaches a desired threshold.
  • Further, a pump device 900 as shown in FIG. 9 may be included to allow the user to continuously inject irrigation fluid without having to disconnect and refill the syringe. The device 900 may be constructed of a syringe 902 with an integrated spring 904 that serves to force the plunger 906 back in the direction of arrow 908 after the user has squeezed the plunger 906 in the direction of arrow 910, toward the syringe body 912 and then released the pressure. The distal end 914 of the syringe 902 is attached to a connector 916. The connector 916 is also connected to a one-way exiting valve 918 and a one-way entering valve 920. Attached at the other side of the one-way exiting valve 918 is tubing leading to the maxillary lavage catheter 100 (shown in FIG. 1). Attached to the other side of the one-way entering valve 920 is a fluid reservoir 922, where the reservoir may be any type of fluid reservoir such as a fluid bath or a fluid bag. In this way, when the user pushers the plunger 906 in the direction of arrow 910, the fluid is force through the exiting one-way valve 918 to the maxillary lavage catheter 100. When the force on the plunger 906 is removed, the spring 904 forces the plunger back, drawing irrigation fluid from the fluid reservoir 922 through the entering one-way valve 920 and into the syringe body 912. Filling of the syringe may also be accomplished by the user pulling back on the plunger 906.
  • Direct visualization markers and/or radiographic markers may be disposed along the lavage catheter 100 distal portion 102. Generally, “direct visualization markers” refers to markers that may be viewed during use with the naked eye or by an endoscope. In one embodiment, flexible distal portion 102 may have a dark color, such as black, dark blue, dark grey or the like or may be transparent, and markers may have a light color, such as white, green, red or the like. In some embodiments, markers may have different colors and/or different widths to facilitate distinguishing the markers from one another during use. This contrast in colors may facilitate viewing the markers in a darkened operation room and/or when using an endoscope inside a patient in the presence of blood. Additionally one or more illumination fibers may be included in the lavage catheter 100 to confirm access of the maxillary sinus.
  • Lavage catheter 100 is configured to irrigate into and suction fluids out of the maxillary sinus. Lavage catheter 100 is sized appropriately to be delivered into adult as well as pediatric maxillary sinuses. Lavage catheter 100 can also be used to deliver diagnostic or therapeutic substances into the sinuses or other areas in the paranasal space. Examples of such diagnostic or therapeutic substances include, but are not limited to: contrast agents, pharmaceutically acceptable salt or dosage form of an antimicrobial agent (e.g., antibiotic, antiviral, anti-parasitic, antifungal, etc.), a corticosteroid or other anti-inflammatory (e.g., an NSAID), a decongestant (e.g., vasoconstrictor), a mucous thinning agent (e.g., an expectorant or mucolytic), an anesthetic agent with or without vasoconstrictor (e.g., Xylocaine with or without epinephrine, Tetracaine with or without epinephrine), an analgesic agent, an agent (anti-allergenic agent) that prevents of modifies an allergic response (e.g., an antihistamine, cytokine inhibitor, leucotriene inhibitor, IgE inhibitor, immunomodulator), an allergen or another substance that causes secretion of mucous by tissues, anti-proliferative agents, hemostatic agents to stop bleeding, cytotoxic agents e.g. alcohol, and biological agents such as protein molecules, stem cells, genes or gene therapy preparations.
  • In the method of the invention, the distal end of the lavage catheter 100 is inserted deep into the maxillary sinus. The actuator 142 is slid from a first position adjacent the proximal hub 132 to a second position adjacent the distal hub 136, there by advancing the atraumatic tip 118 of the distal irrigation tube 114 well into the maxillary sinus. Irrigation is performed as irrigation fluid is pushed through the opening 212 in the atraumatic tip 118 using a syringe or other fluid introduction device attached to the luer connector 126. Once lavage is complete, the actuator 142 is retracted back to its first position adjacent the proximal hub 132 and the lavage catheter 100 is removed from the patient's anatomy.
  • FIG. 3 is a side view of a maxillary lavage catheter 300 according to a further embodiment of the present invention. Similar to the lavage catheter 100 shown in FIGS. 1 and 2, the irrigation tube 314 coaxially surrounds the elongate shaft 308 (see FIG. 4). Once the distal end 310 of the catheter 300 is positioned behind the uncinate near the maxillary sinus, the distal end 316 of the irrigation tube 314 is advanced by sliding actuator 342 on handle 344 in the distal direction, thereby advancing irrigation tube 314 into the sinus where irrigation occurs. FIG. 3 shows the irrigation tube 314 prior to advancement, and FIG. 4 shows the irrigation tube 314 following advancement into the sinus. The irrigation tube 314 is sufficiently flexible to navigate through the infundibular space, enter the sinus atraumatically, and provide adequate irrigation when flushed with sterile water, saline, or other liquid from a standard syringe or fluid injection device. Irrigation takes place through the elongate shaft 308 and through irrigation holes at the distal end 316 of the irrigation tube 314. The narrow tip envelope and curve allow for easy access and positioning behind the uncinate. An atraumatic tip 318 prevents damage to surrounding tissue while locating the ostium. The small distal end 316 (approximately 1.5 mm to 2.5 mm in diameter) makes it easier to position the distal end 316 of the irrigation tube 314 behind the uncinate. This provides the irrigation tube 314 direction once it is actuated. The side irrigation holes of the distal end 316 and front blockage at the atraumatic tip 318 allow for spray in all directions to effectively clean the sinus. The atraumatic ball tip 318 minimizes the risk of tissue damage while accessing the sinus.
  • FIG. 5 is a side view of a maxillary lavage catheter 500 according to a further embodiment of the present invention. In this embodiment, the irrigation tube 514 is coaxially surrounded by the elongate shaft 508 (see FIG. 6). Once the distal end 510 of the catheter 500 is positioned behind the uncinate near the maxillary sinus, the distal end 516 of the irrigation tube 514 is advanced by sliding actuator 542 in the distal direction, thereby advancing irrigation tube 514 into the sinus where irrigation occurs. FIG. 5 shows the irrigation tube 514 prior to advancement, and FIG. 6 shows the irrigation tube 514 following advancement into the sinus. The irrigation tube 514 is sufficiently flexible to navigate through the infundibular space, enter the sinus atraumatically, and provide adequate irrigation. Irrigation takes place through the elongate shaft 508 and through irrigation holes at the distal end 516 of the irrigation tube 514. The narrow tip envelope and curve allow for easy access and positioning behind the uncinate. An atraumatic tip 518 prevents damage to surrounding tissue while locating the ostium. The small distal end 516 (approximately 1.3 mm to 2.3 mm in diameter) makes it easier to position the distal end 516 of irrigation tube 514 behind the uncinate. This provides the irrigation tube 514 direction once it is actuated. The side irrigation holes and front blockage on the atraumatic tip 518 allow for spray in all directions to effectively clean the sinus. The atraumatic ball tip 518 minimizes the risk of tissue damage while accessing the sinus.
  • Delivery of the lavage catheter 100 of the current invention may be additionally or alternatively visualized by using an endoscope or by using fluoroscopy, electromagnetic or optical guidance, including 3-dimensional visualization such as CT or MRI visualization or other known visualization techniques. In one embodiment of the invention, one or more light fibers may be included in the lumen of the distal irrigation tube 114 such that advancement of the atraumatic tip 118 into the maxillary sinus can be observed as a result of the transillumination of the maxillary sinus. Alternatively, the distal irrigation tube 114 may comprise a dual lumen tube, one lumen for irrigation and one for containing the light fibers for transillumination of the maxillary sinus. In the embodiment of the invention shown in FIG. 7 a light fiber (or light fibers) can be integrated into the catheter 700 at the distal tip end 702 and the actuator 704 of the handle 706. The catheter 700 may be advanced into the sinus and positioned therein under endoscopic visualization. Once the catheter 700 is advanced into the sinus, the endoscope may be removed so that it can be used as a light source. The light end of the endoscope is placed at light access point 708 by placing it directly onto the actuator 704 as shown in FIG. 7. This configuration eliminates the need for an extra light source and requires no additional steps by the user. After confirmation, the endoscope can be placed back into the nasal cavity for further endoscopic visualization.
  • In an alternative embodiment, an extra light source could be provided to connect to the one or more light fibers. Connection of the one or more light fibers to the light source can be accomplished with a rotating light cable connector 1000 as shown in FIGS. 10A and 10B. Using this light cable connector 1000, the user can rotate the maxillary lavage catheter 100 while it is attached to a light source without the weight of the light cable (not shown) inhibiting rotation.
  • As shown in FIG. 10B, the connector 1000 contains a grommet 1002 that is attached to the proximal end 1112 of the tubing 1004. The light fiber 1006 (which may actually be one or more light fibers) is contained within the lumen 1008 of the tubing 1004. The grommet 1002 is designed to float freely inside the connector 1002, thereby allowing the tubing 1004 to spin freely when it is rotated. The grommet 1002 is larger than the distal hole 1010 of the connector 1000, such that the grommet 1002, and therefore the tubing 1004 is prevented from being pulled from the connector 1000 longitudinally.
  • The invention has been described with reference to certain examples or embodiments of the invention, but various additions, deletions, alterations and modifications may be made to those examples and embodiments without departing from the intended spirit and scope of the invention. For example, any element or attribute of one embodiment or example may be incorporated into or used with another embodiment or example, unless otherwise specified or if to do so would render the embodiment or example unsuitable for its intended use. Also, where the steps of a method or process have been described or listed in a particular order, the order of such steps may be changed unless otherwise specified or unless doing so would render the method or process unworkable for its intended purpose. All reasonable additions, deletions, modifications and alterations are to be considered equivalents of the described examples and embodiments and are to be included within the scope of the following claims.

Claims (22)

What is claimed is:
1. A catheter for the lavage of a maxillary sinus comprising:
a distal portion comprising:
an elongate shaft with a bend angle of between about 90 degrees and 140 degrees,
a distal irrigation tube in coaxial arrangement with said elongate shaft,
a distal hub,
a proximal hub, and
an actuator between said distal hub and said proximal hub for advancing the distal irrigation tube into the maxillary sinus; and
a proximal portion comprising an irrigation luer and irrigation tubing.
2. The catheter of claim 1 wherein the irrigation tip comprises a distal tip opening.
3. The catheter of claim 2 wherein the irrigation tip further comprises one or more radially facing openings.
4. The catheter of claim 1 wherein the distal irrigation tube comprises a flexible material selected from the group consisting of nylon, polyethylene, polyether ether ketone or polyether block amides.
5. The catheter of claim 4 wherein the distal irrigation tube is a polyether block amide.
6. The catheter of claim 1 further comprising one or more direct visualization markers.
7. The catheter of claim 1 further comprising one or more radiographic markers.
8. The catheter of claim 1 wherein the distal irrigation tube surrounds the elongate shaft.
9. The catheter of claim 1 wherein the distal irrigation tube is surrounded by the elongate shaft.
10. The catheter of claim 1 further comprising an illuminating fiber.
11. The catheter of claim 1 wherein the distal irrigation tip has a tapered configuration.
12. The catheter of claim 1 further comprising a pulsation device.
13. The catheter of claim 12 wherein the pulsation device comprises a valve assembly.
14. A catheter for the lavage of a maxillary sinus comprising:
a distal portion comprising:
an elongate shaft with a bend angle of between about 90 degrees and 140 degrees,
a distal irrigation tube in coaxial arrangement with said elongate shaft, and
a handle comprising an actuator, and
a proximal portion comprising an irrigation luer and irrigation tubing,
wherein the actuator is useful for advancing the distal irrigation tube into the maxillary sinus.
15. The catheter of claim 14 wherein the actuator comprises a light access port and wherein the distal portion further comprises an illuminating fiber.
16. A kit for the lavage of a maxillary sinus, said kit comprising a catheter and an endoscope,
wherein the catheter comprises a distal portion and a proximal portion,
said distal portion comprising:
an elongate shaft with a bend angle of between about 90 degrees and 140 degrees,
a distal irrigation tube in coaxial arrangement with said elongate shaft,
an illuminating fiber, and
a handle comprising an actuator, said actuator having a light access port and
said proximal portion comprising an irrigation luer and irrigation tubing,
wherein the actuator is useful for advancing the distal irrigation tube into the maxillary sinus; and
an endoscope for insertion into the light access port.
17. A method for lavaging a maxillary sinus, said method comprising:
positioning an lavage catheter comprising a proximal portion, and a distal portion in the nasal anatomy of a patient, wherein the distal portion comprises an irrigation tip;
connecting a fluid source to the irrigation catheter;
with one hand, advancing the irrigation tip into the maxillary sinus; and
delivering fluid to the maxillary sinus from the fluid source though the lavage catheter.
18. The method of claim 17 wherein the delivering the fluid occurs at a flow rate of between 50 ml/min and 250 ml/min.
19. The method of claim 17 wherein the fluid is selected from the group consisting of water, saline, contrast agents, antimicrobial agents anti-inflammatory agents, decongestants, mucous thinning agents, anesthetic agents, analgesic agents, anti-allergenic agents, allergens, anti-proliferative agents, hemostatic agents, cytotoxic agents, and biological agents or combinations of any of the above.
20. A kit for the lavage of a maxillary sinus, said kit comprising a maxillary lavage catheter,
wherein the catheter comprises a distal portion and a proximal portion,
said distal portion comprising:
an elongate shaft with a bend angle of between about 90 degrees and 140 degrees,
a distal irrigation tube in coaxial arrangement with said elongate shaft,
an illuminating fiber, and
a handle comprising an actuator,
said proximal portion comprising an irrigation luer and irrigation tubing,
wherein the actuator is useful for advancing the distal irrigation tube into the maxillary sinus; and
a illuminating fiber connector for connecting said illuminating fiber to a light source, wherein the illuminating fiber connector allows for rotation of the catheter while the catheter is connected to the light source.
21. A kit for the lavage of a maxillary sinus, said kit comprising a catheter and fluid delivery system,
wherein the catheter comprises a distal portion and a proximal portion,
said distal portion comprising:
an elongate shaft with a bend angle of between about 90 degrees and 140 degrees,
a distal irrigation tube in coaxial arrangement with said elongate shaft,
an illuminating fiber, and
a handle comprising an actuator,
said proximal portion comprising an irrigation luer and irrigation tubing,
wherein the actuator is useful for advancing the distal irrigation tube into the maxillary sinus; and
a fluid delivery system for providing continuous fluid delivery to the catheter.
22. The kit of claim 21 wherein the fluid delivery system comprises:
a syringe;
a fluid reservoir;
a first one-way valve for directing fluid from the syringe into the catheter when pressure is applied to the syringe and a second one-way valve for directing fluid from the fluid reservoir into the catheter when pressure is released from the syringe.
US13/800,163 2012-04-13 2013-03-13 Devices and Method for Maxillary Sinus Lavage Abandoned US20130274600A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US201261623730P true 2012-04-13 2012-04-13
US201261675595P true 2012-07-25 2012-07-25
US13/800,163 US20130274600A1 (en) 2012-04-13 2013-03-13 Devices and Method for Maxillary Sinus Lavage

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US13/800,163 US20130274600A1 (en) 2012-04-13 2013-03-13 Devices and Method for Maxillary Sinus Lavage
PCT/US2013/036372 WO2013155415A1 (en) 2012-04-13 2013-04-12 Devices and method for maxillary sinus lavage
EP13722164.4A EP2836248A1 (en) 2012-04-13 2013-04-12 Devices and method for maxillary sinus lavage
CA2869866A CA2869866A1 (en) 2012-04-13 2013-04-12 Devices and method for maxillary sinus lavage
MX2014012379A MX2014012379A (en) 2012-04-13 2013-04-12 Devices and method for maxillary sinus lavage.
US15/787,632 US10166369B2 (en) 2012-04-13 2017-10-18 Devices and method for maxillary sinus lavage

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US15/787,632 Continuation US10166369B2 (en) 2012-04-13 2017-10-18 Devices and method for maxillary sinus lavage

Publications (1)

Publication Number Publication Date
US20130274600A1 true US20130274600A1 (en) 2013-10-17

Family

ID=49325703

Family Applications (2)

Application Number Title Priority Date Filing Date
US13/800,163 Abandoned US20130274600A1 (en) 2012-04-13 2013-03-13 Devices and Method for Maxillary Sinus Lavage
US15/787,632 Active US10166369B2 (en) 2012-04-13 2017-10-18 Devices and method for maxillary sinus lavage

Family Applications After (1)

Application Number Title Priority Date Filing Date
US15/787,632 Active US10166369B2 (en) 2012-04-13 2017-10-18 Devices and method for maxillary sinus lavage

Country Status (5)

Country Link
US (2) US20130274600A1 (en)
EP (1) EP2836248A1 (en)
CA (1) CA2869866A1 (en)
MX (1) MX2014012379A (en)
WO (1) WO2013155415A1 (en)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150100042A1 (en) * 2013-10-07 2015-04-09 Impel Neuropharma Inc. Muroid Family Nasal Device
US20150230700A1 (en) * 2013-12-17 2015-08-20 Biovision Technologies, Llc Stabilized surgical device for performing a sphenopalatine ganglion block procedure
US20160271375A1 (en) * 2013-12-17 2016-09-22 Biovision Technologies, Inc. Methods for treating sinus diseases
USD772406S1 (en) 2014-12-16 2016-11-22 Biovision Technologies, Llc Surgical device
USD772408S1 (en) 2014-07-09 2016-11-22 Simplicity Nasal dilator
US9516995B2 (en) * 2013-12-17 2016-12-13 Biovision Technologies, Llc Surgical device for performing a sphenopalatine ganglion block procedure
US9597179B2 (en) 2011-07-25 2017-03-21 Rainbow Medical Ltd. Sinus stent
US20170119953A1 (en) * 2015-10-30 2017-05-04 Medtronic Xomed, Inc. Method and Apparatus for Irrigation
US20170119952A1 (en) * 2015-10-30 2017-05-04 Medtronic Xomed, Inc. Method and Apparatus for Irrigation
US20170128696A1 (en) * 2013-11-21 2017-05-11 Jet Medical, Inc. Method for facilitating intranasal guidance
US9694163B2 (en) 2013-12-17 2017-07-04 Biovision Technologies, Llc Surgical device for performing a sphenopalatine ganglion block procedure
USD802127S1 (en) * 2014-06-02 2017-11-07 Simplicity, Llc Nasal dilator
USD834188S1 (en) * 2014-06-02 2018-11-20 Simplicity, Llc Nasal dilator
US10166369B2 (en) 2012-04-13 2019-01-01 Acclarent, Inc. Devices and method for maxillary sinus lavage
WO2019046486A1 (en) * 2017-08-31 2019-03-07 Cornell University Catheter system and method of use

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3885561A (en) * 1971-12-15 1975-05-27 Charles N Mazal Cami Catheter
US5152749A (en) * 1991-06-28 1992-10-06 American Medical Systems, Inc. Instrument placement apparatus
US20070185435A1 (en) * 2004-11-15 2007-08-09 Cytyc Corporation Method and System for Drug Delivery
US20080183128A1 (en) * 2007-01-24 2008-07-31 John Morriss Methods, devices and systems for treatment and/or diagnosis of disorders of the ear, nose and throat
US20120101433A1 (en) * 2010-10-21 2012-04-26 William De Jesus Alvarez Sinusal guide cannula and kit for irrigation, suction and washing

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2506056C2 (en) 2008-09-18 2014-02-10 Аккларент, Инк. Methods and apparatus for treating ear, nose and throat diseases
US7803150B2 (en) 2004-04-21 2010-09-28 Acclarent, Inc. Devices, systems and methods useable for treating sinusitis
US7462175B2 (en) * 2004-04-21 2008-12-09 Acclarent, Inc. Devices, systems and methods for treating disorders of the ear, nose and throat
US20060063973A1 (en) 2004-04-21 2006-03-23 Acclarent, Inc. Methods and apparatus for treating disorders of the ear, nose and throat
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US20060095006A1 (en) 2004-10-29 2006-05-04 Chang-Ming Yang Screw driver structure
US7955315B2 (en) * 2006-07-24 2011-06-07 Ethicon, Inc. Articulating laparoscopic device and method for delivery of medical fluid
US8241266B2 (en) * 2007-04-05 2012-08-14 Entellus Medical, Inc. Apparatus and method for treatment of ethmoids
US20090024084A1 (en) * 2007-07-16 2009-01-22 Peritec Biosciences Ltd. Multi-lumen catheter assembly and method of providing relative motion thereto
MX2011001099A (en) 2008-07-30 2011-03-15 Acclarent Inc Paranasal ostium finder devices and methods.
WO2013016052A2 (en) 2011-07-25 2013-01-31 Acclarent, Inc. Devices and methods for transnasal irrigation or suctioning of the sinuses
KR20140049566A (en) * 2011-07-25 2014-04-25 아클라런트, 인코포레이션 Devices and methods for transnasal dilation and irrigation of the sinuses
US20130274600A1 (en) 2012-04-13 2013-10-17 Acclarent, Inc. Devices and Method for Maxillary Sinus Lavage
US9579448B2 (en) 2012-04-13 2017-02-28 Acclarent, Inc. Balloon dilation catheter system for treatment and irrigation of the sinuses
US20180104404A1 (en) 2016-10-14 2018-04-19 Acclarent, Inc. Apparatus and method for irrigating sinus cavity

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3885561A (en) * 1971-12-15 1975-05-27 Charles N Mazal Cami Catheter
US5152749A (en) * 1991-06-28 1992-10-06 American Medical Systems, Inc. Instrument placement apparatus
US20070185435A1 (en) * 2004-11-15 2007-08-09 Cytyc Corporation Method and System for Drug Delivery
US20080183128A1 (en) * 2007-01-24 2008-07-31 John Morriss Methods, devices and systems for treatment and/or diagnosis of disorders of the ear, nose and throat
US20120101433A1 (en) * 2010-10-21 2012-04-26 William De Jesus Alvarez Sinusal guide cannula and kit for irrigation, suction and washing

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9597179B2 (en) 2011-07-25 2017-03-21 Rainbow Medical Ltd. Sinus stent
US10166369B2 (en) 2012-04-13 2019-01-01 Acclarent, Inc. Devices and method for maxillary sinus lavage
US20150100042A1 (en) * 2013-10-07 2015-04-09 Impel Neuropharma Inc. Muroid Family Nasal Device
US9993612B2 (en) 2013-11-21 2018-06-12 Jet Medical, Inc. Method for facilitating intranasal guidance
US20170128696A1 (en) * 2013-11-21 2017-05-11 Jet Medical, Inc. Method for facilitating intranasal guidance
US9999747B2 (en) 2013-11-21 2018-06-19 Jet Medical, Inc. System for facilitating intranasal guidance
US9839770B2 (en) 2013-11-21 2017-12-12 Jet Medical, Inc. System and method for facilitating intranasal guidance
US9849265B2 (en) * 2013-11-21 2017-12-26 Jet Medical, Inc. Method for facilitating intranasal guidance
US9516995B2 (en) * 2013-12-17 2016-12-13 Biovision Technologies, Llc Surgical device for performing a sphenopalatine ganglion block procedure
US9510743B2 (en) * 2013-12-17 2016-12-06 Biovision Technologies, Llc Stabilized surgical device for performing a sphenopalatine ganglion block procedure
US10046143B2 (en) 2013-12-17 2018-08-14 Biovision Technologies Llc Surgical device for performing a sphenopalatine ganglion block procedure
US10016580B2 (en) * 2013-12-17 2018-07-10 Biovision Technologies, Llc Methods for treating sinus diseases
US20160271375A1 (en) * 2013-12-17 2016-09-22 Biovision Technologies, Inc. Methods for treating sinus diseases
US20160135671A1 (en) * 2013-12-17 2016-05-19 Biovision Technologies, Llc Method of performing a sphenopalatine ganglion block procedure
US9248266B2 (en) * 2013-12-17 2016-02-02 Biovision Technologies, Llc Method of performing a sphenopalatine ganglion block procedure
US20150258315A1 (en) * 2013-12-17 2015-09-17 Biovision Technologies, Llc Method of performing a sphenopalatine ganglion block procedure
US20180042471A1 (en) * 2013-12-17 2018-02-15 Biovision Technologies, Llc Method of performing a sphenopalatine ganglion block procedure
US20150230700A1 (en) * 2013-12-17 2015-08-20 Biovision Technologies, Llc Stabilized surgical device for performing a sphenopalatine ganglion block procedure
US9839347B2 (en) * 2013-12-17 2017-12-12 Biovision Technologies Llc Method of performing a sphenopalatine ganglion block procedure
US9694163B2 (en) 2013-12-17 2017-07-04 Biovision Technologies, Llc Surgical device for performing a sphenopalatine ganglion block procedure
USD834188S1 (en) * 2014-06-02 2018-11-20 Simplicity, Llc Nasal dilator
USD802127S1 (en) * 2014-06-02 2017-11-07 Simplicity, Llc Nasal dilator
USD792589S1 (en) 2014-07-09 2017-07-18 Simplicity, Llc Nasal dilator
USD772408S1 (en) 2014-07-09 2016-11-22 Simplicity Nasal dilator
USD804665S1 (en) 2014-07-09 2017-12-05 Simplicity, Llc Nasal dilator
USD772406S1 (en) 2014-12-16 2016-11-22 Biovision Technologies, Llc Surgical device
US20170119952A1 (en) * 2015-10-30 2017-05-04 Medtronic Xomed, Inc. Method and Apparatus for Irrigation
US20170119953A1 (en) * 2015-10-30 2017-05-04 Medtronic Xomed, Inc. Method and Apparatus for Irrigation
WO2019046486A1 (en) * 2017-08-31 2019-03-07 Cornell University Catheter system and method of use

Also Published As

Publication number Publication date
US20180036512A1 (en) 2018-02-08
CA2869866A1 (en) 2013-10-17
EP2836248A1 (en) 2015-02-18
WO2013155415A1 (en) 2013-10-17
US10166369B2 (en) 2019-01-01
MX2014012379A (en) 2014-11-26

Similar Documents

Publication Publication Date Title
CN102458553B (en) Frontal sinus dilatation catheter
US8702662B2 (en) Body-space drainage-tube debris removal
US5695479A (en) Instrument, system, kit and method for catheterization procedures
US8623043B1 (en) Device and method for treatment of sinusitis
US5693065A (en) Frontal sinus stent
US9055965B2 (en) Devices, systems and methods useable for treating sinusitis
US9101739B2 (en) Balloon catheter inflation apparatus and methods
US8172828B2 (en) Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures
US5257979A (en) Instrument for catheterization
US20130023729A1 (en) Airway cleaning and visualization
US8657846B2 (en) Guide catheter and method of use
AU2011305900B2 (en) Medical device for treatment of a sinus opening
EP2902066A1 (en) Airway cleaning and visualization
AU2006292818B2 (en) Methods and apparatus for treating disorders of the ear, nose and throat
US20080058595A1 (en) Medical device introduction systems and methods
AU2009293312B2 (en) Methods and apparatus for treating disorders of the ear nose and throat
ES2222570T3 (en) Vacuum system and deep wounds irrigation.
EP2121108B1 (en) Apparatus for treatment of sinusitis
US8968269B2 (en) Multi-conduit balloon catheter
US10238846B2 (en) Sinus balloon dilation catheters and sinus surgery tools
US4696668A (en) Double balloon nasobiliary occlusion catheter for treating gallstones and method of using the same
US9282986B2 (en) Method and articles for treating the sinus system
US7306574B2 (en) Steerable dilatation system, dilator, and related methods for stepped dilatation
CN104220014B (en) Method and system for expanding the Eustachian tube
US20080275483A1 (en) Methods and Apparatus for Treating Disorders of the Ear Nose and Throat

Legal Events

Date Code Title Description
AS Assignment

Owner name: ACCLARENT, INC., CALIFORNIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:JENKINS, THOMAS ROY;CHAN, JESSICA KRISTEN;LIBERATORE, JESSICA;AND OTHERS;SIGNING DATES FROM 20120905 TO 20120918;REEL/FRAME:029987/0374