US20130210708A1 - Methods of inhibiting and treating bacterial biofilms by metal chelators - Google Patents

Methods of inhibiting and treating bacterial biofilms by metal chelators Download PDF

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Publication number
US20130210708A1
US20130210708A1 US13/706,042 US201313706042A US2013210708A1 US 20130210708 A1 US20130210708 A1 US 20130210708A1 US 201313706042 A US201313706042 A US 201313706042A US 2013210708 A1 US2013210708 A1 US 2013210708A1
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United States
Prior art keywords
bacteria
biofilm
metal chelator
lactoferrin
proteinaceous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US13/706,042
Inventor
Pradeep K. Singh
Michael J. Welsh
Everett P. Greenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Iowa Research Foundation (UIRF)
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University of Iowa Research Foundation (UIRF)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US37346102P priority Critical
Priority to PCT/US2003/012128 priority patent/WO2003088914A2/en
Priority to US10/958,923 priority patent/US7446089B2/en
Priority to US12/288,449 priority patent/US8343911B2/en
Application filed by University of Iowa Research Foundation (UIRF) filed Critical University of Iowa Research Foundation (UIRF)
Priority to US13/706,042 priority patent/US20130210708A1/en
Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT reassignment NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT CONFIRMATORY LICENSE (SEE DOCUMENT FOR DETAILS). Assignors: UNIVERSITY OF IOWA
Assigned to UNIVERSITY OF IOWA RESEARCH FOUNDATION reassignment UNIVERSITY OF IOWA RESEARCH FOUNDATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SINGH, PRADEEP K., WELSH, MICHAEL J., GREENBERG, E. PETER
Publication of US20130210708A1 publication Critical patent/US20130210708A1/en
Application status is Abandoned legal-status Critical

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