Connect public, paid and private patent data with Google Patents Public Datasets

Intervertebral implant

Download PDF

Info

Publication number
US20110118843A1
US20110118843A1 US13012626 US201113012626A US2011118843A1 US 20110118843 A1 US20110118843 A1 US 20110118843A1 US 13012626 US13012626 US 13012626 US 201113012626 A US201113012626 A US 201113012626A US 2011118843 A1 US2011118843 A1 US 2011118843A1
Authority
US
Grant status
Application
Patent type
Prior art keywords
surface
front
implant
dimensional
body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US13012626
Inventor
Claude Mathieu
Christopher Marden John Cain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DePuy Synthes Products Inc
Original Assignee
Synthes USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A61F2/4465Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages having a circular or kidney shaped cross-section substantially perpendicular to the axis of the spine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8052Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates immobilised relative to screws by interlocking form of the heads and plate holes, e.g. conical or threaded
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A61F2/447Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages substantially parallelepipedal, e.g. having a rectangular or trapezoidal cross-section
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86Threaded wires, pins or screws; Nuts therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/30004The prosthesis made from materials having different values of a given property at different locations within the same prosthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes, grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/30774Apertures or holes, e.g. of circular cross section internally-threaded
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes, grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/30777Oblong apertures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes, grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/3079Stepped or enlarged apertures, e.g. having discrete diameter changes
    • A61F2002/30794Stepped or enlarged apertures, e.g. having discrete diameter changes the enlarged portion being used for receiving and hiding a screw head, a nut or a closing cap
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external and/or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes, grooves
    • A61F2002/30841Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2002/4475Joints for the spine, e.g. vertebrae, spinal discs hollow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys

Abstract

The intervertebral implant is in the form of a three-dimensional structure (10) comprising (a) a top side (1) and an underside (2) which are designed to rest against the end plates of two adjacent vertebras, (b) a left side face (3) and a right side face (4), (c) a front face (5) and a rear face (6), (d) a horizontal center plane situated between the top side (1) and the underside (2), (e) a vertical center plane (8) situated between the left side face (3) and the right side face (8) and (f) a plurality of boreholes (9) passing through the implant structure (10) that are designed to receive longitudinal affixation elements (20), the axes (19) of said elements intersecting the horizontal center plane (7). At least one of the boreholes (9) is designed in a manner that the affixation element (10) received in it can be rigidly connected to the intervertebral implant. Said connection is implemented using a thread or by matching conical surfaces.

Description

    CROSS-REFERENCE TO RELATED APPLICATIONS
  • [0001]
    This application is a continuation of U.S. patent application Ser. No. 12/574,222, filed Oct. 6, 2009, which is a continuation of U.S. patent application Ser. No. 11/751,757, filed May 22, 2007, now U.S. Pat. No. 7,618,456, which is a continuation of U.S. patent application Ser. No. 10/923,534, filed Aug. 19, 2004, now U.S. Pat. No. 7,232,464, which is a continuation of International Application No. PCT/CH02/00099, filed Feb. 19, 2002. The entire contents of these applications are expressly incorporated herein by reference thereto.
  • FIELD OF THE INVENTION
  • [0002]
    The present invention relates to an intervertebral implant.
  • BACKGROUND OF THE INVENTION
  • [0003]
    Such an intervertebral implant is known from the British patent document 2,207,607 A which discloses a horseshoe implant structure having a plurality of cylindrical holes. These holes are fitted with inner, smooth surfaces and comprise only one stop for the heads of the bone screws to be inserted into them. This design incurs the drawback that the inserted affixation screws may be anchored into the bone only by their shanks, a rigid connection with the horseshoe shaped intervertebral implant being lacking. As soon as the anchoring of the bone screw in the bone is weakened, the intervertebral implant becomes displaceable relative to the screw and the bone screws may then migrate while endangering the blood vessels. Moreover the loosening of the intervertebral implant may entail pseudoarthrosis.
  • [0004]
    The above cited state of the art is intended merely to elucidate the background of the present invention but it does imply that the cited state of the art had actually been made public or was publicly known at the time of this application or at the time of its priority.
  • BRIEF SUMMARY OF THE INVENTION
  • [0005]
    The objective of the present invention is palliation. This invention creates an intervertebral implant which is able to rigidly connect to bone affixation means in a manner that even in the event of bone structure weakening, loosening between the intervertebral implant and the bone affixation means shall be precluded.
  • [0006]
    The above problem is solved in the present invention by an intervertebral implant exhibiting the features of claim 1.
  • [0007]
    The advantages offered by the present invention substantially are attained by the rigid, that is by the firm connection between the intervertebral implant and the longitudinal affixing elements. Basically two different embodiment modes are available to attain said rigid connection.
  • [0008]
    In a first embodiment mode, at least one of the boreholes shall be internally threaded. In this case a matching bone screw fitted with a thread head may be rigidly screwed into the implant.
  • [0009]
    As regards a second embodiment mode, a front plate is mounted at the front surface of the three dimensional (3D) implant structure so as to be configured vertically to the horizontal center plane of the intervertebral implant, said boreholes passing through said front plate and receiving the anchored longitudinal affixation elements. Compared to the state of the art of a two-part implant, wherein a front plate is implanted in a separate operational step, the above design of the present invention offers the advantage that the intervertebral implant shall be implanted in a single step and hence in a simple and quicker manner. The invention offers a further advantage in that the intervertebral implant shall be affixed as frontally to the vertebra as possible, namely at a place where good bone material may be expected to be. As a result anterior displacement is restricted without thereby incurring greater danger to the surrounding structures than when using a state of the art intervertebral implant. The load still is being borne by the compressed vertebral implant, not by the front plate or the affixation screws.
  • [0010]
    In yet another embodiment mode of the present invention, the front plate is displaceably configured in the 3D implant structure in order that it may move vertically relative to this 3D implant structure. “Stress shielding” is attained in this manner (namely protection from or neutralization of mechanical stresses), and as a result the end plates may gradually match the intervertebral implant during the healing process.
  • [0011]
    As regards a further embodiment, the front plate is made of a material different from that of the 3D implant structure.
  • [0012]
    As regards a further embodiment of the present invention, at least one borehole tapers conically towards its underside and as a result a bone screw fitted with a matching conical head may be rigidly anchored in said borehole. Preferably the conical borehole exhibits a cone angle smaller than the resultant angle of friction. Appropriately the borehole's conicity shall be 1:3.75 to 1:20, preferably 1:5 to 1:15.
  • [0013]
    As regards a further embodiment mode of the present invention, the intervertebral implant side faces shall all be substantially convex.
  • [0014]
    Appropriately the intervertebral implant's top and/or undersides are not planar but convex. In this manner better matching to the end plates of the adjacent vertebras may be attained.
  • [0015]
    The boreholes preferably shall not pass through the left and right intervertebral implant side faces. Preferably again no borehole shall run through the front surface.
  • [0016]
    As regards a further preferred embodiment mode of the present invention, at least two boreholes shall be mutually parallel. This features facilitates inserting the vertebral implant during implantation.
  • [0017]
    As regards another preferred embodiment mode of the present invention, at least two boreholes shall run in mutually divergent manner as seen from the front side. As a result the bone screws shall move into a vertebral region offering better bone quality than found at the vertebra's center. Appropriately the borehole axes subtend an angle of 25 degrees to 70 degrees, preferably 35 degrees to 55 degrees with the horizontal center plane. This feature offers improved access for screw insertion.
  • [0018]
    As regards a further embodiment mode of the present invention, the boreholes shall not cross the horizontal center plane.
  • [0019]
    Depending on circumstance, two, three, four or even more longitudinal affixation elements may rigidly connected to the intervertebral implant; appropriately at least one affixation element shall pass through the top side and at least one affixation element shall pass through the intervertebral implant side.
  • [0020]
    Preferably the longitudinal affixation elements shall be bone screws comprising a head and a shank, said head preferably being fitted with an external thread that matches the inner thread of the intervertebral implant's borehole. As regards a second appropriate connection, preferably a bone screw shall be used of which the head tapers conically in the direction of the shank, the head's conicity corresponding to that of the intervertebral implant's borehole.
  • [0021]
    Regarding a further embodiment mode, at least two longitudinal affixation elements pass through the top side and at least two longitudinal affixation elements pass through the underside. In this manner the intervertebral implant is optimally anchored into the adjacent vertebras.
  • [0022]
    Preferably the screw-shaped longitudinal affixation elements exhibit a self-boring and self-tapping external thread. The longitudinal affixation elements also may be designed as unthreaded cylindrical pins fitted with a boring tip, preferably in the form of a trocar.
  • [0023]
    In another embodiment variation, the longitudinal affixation elements are spiral springs; lastly said longitudinal affixation elements also may be designed as single or multi-wing spiral blades.
  • [0024]
    In a further embodiment mode of the present invention, the longitudinal affixation element tip may be anchored in the structure of the intervertebral implant, as a result of which the head of the longitudinal affixation element may be anchored in the adjacent vertebra.
  • [0025]
    In a further embodiment mode of the present invention, the longitudinal affixation element head exhibits a widened diameter; also a support disk is provided for said head to rest against the vertebra.
  • [0026]
    The intervertebral implant may be made of any physiologically compatible material, though appropriately the implant structure shall consist of a physiologically compatible plastic, preferably an unreinforced plastic. The advantage offered by the invention over the already known, fiber-reinforced plastics used in implantology is that no reinforcing fibers will be bared—an eventuality that would be clinically disadvantageous. Appropriately bone screws consisting of non-reinforced plastic of which the external threads exhibit load bevels of 11 degrees to 14 degrees, preferably 12 degrees to 13 degrees, may be used in such an implant structure. The relatively small slope of the load bevel implements high clamping forces, as a result of which radial elongation and danger of cracking of the plastic are reduced. Appropriately the bone screws' external thread exhibits the bones at an angular pitch of 6 degrees to 10 degrees, preferably 7 degrees to 9 degrees. This particular angular pitch produces thread self-locking and prevents the bone screw from loosening on its own.
  • [0027]
    The borehole may be in the form of a metal bush fitted with an inner thread for the purpose of improving anchoring the bone screw in the plastic implant structure. The intervertebral implant also may consist partly of plastic and, in the borehole zones, of metal. This design offers improved guidance and anchoring of the bone screw in the intervertebral implant.
  • [0028]
    As regards a further preferred embodiment mode, the inside borehole walls are smooth, the thread head of a metallic, longitudinal affixation element cutting or tapping into said smooth wall.
  • BRIEF DESCRIPTION OF THE SEVERAL VIEWS OF THE DRAWINGS
  • [0029]
    The present invention and further embodiment modes of it are elucidated below in relation to the partly schematic representation of two illustrative embodiments.
  • [0030]
    FIG. 1 is a perspective view including a partial section of the intervertebral implant with inserted bone screws,
  • [0031]
    FIG. 2 is a front view of the intervertebral implant of FIG. 1,
  • [0032]
    FIG. 3 is a side view of the intervertebral implant of FIG. 1,
  • [0033]
    FIG. 4 is a top view of the intervertebral implant of FIG. 1,
  • [0034]
    FIG. 5 is a front view of the intervertebral implant with a front insert, in partial section,
  • [0035]
    FIG. 6 is a vertical, longitudinal section of the intervertebral implant of FIG. 5, and
  • [0036]
    FIG. 7 is a horizontal cross-section of the intervertebral implant of FIG. 5.
  • DETAILED DESCRIPTION OF THE INVENTION
  • [0037]
    The intervertebral implant of FIGS. 1 through 4 consists of a 3D structure 10 exhibiting both a convex top side 1 and a convex underside 2, the two sides each being designed to rest against the end plates of two adjacent vertebras. To attain improved anchoring, the top side 1 and the underside 2 may be topographically shaped and be fitted with grooves, ribs or teeth, or their surfaces may be merely roughened.
  • [0038]
    The 3D implant structure 10 moreover comprises a left side face 3 and a right side face 4, also a front face 5 and a rear face 6. The implant structure 10 also may be hollow and its outer surface may comprise perforations.
  • [0039]
    The implant structure 10 comprises a plurality of boreholes 9 passing through it and receiving longitudinal affixation elements 20. Preferably four such boreholes 9 shall be provided.
  • [0040]
    At least one of the boreholes 9 is designed in a way that the longitudinal affixation element 20 received therein may be rigidly connected to the intervertebral implant. The boreholes 9 are conical for that purpose.
  • [0041]
    Preferably the affixation elements 20 are bone screws having a head 21 and a tip 22. The head 21 conically tapers toward the shank 23, the conicity of the head 21 corresponding to the conicity of the borehole 9. Moreover the four boreholes 9 may be fitted with inner threads 11.
  • [0042]
    As regards the embodiment variation shown in FIGS. 5 through 7, the 3D structure 10 is fitted at its front face 5 with a preferably metallic insert 8 into which the affixation elements 20 may be anchored. The insert 8 is mounted in vertically displaceable manner in the 3D structure 10.
  • [0043]
    While the invention has been shown and described herein with reference to particular embodiments, it is to be understood that the various additions, substitutions, or modifications of form, structure, arrangement, proportions, materials, and components and otherwise, used in the practice and which are particularly adapted to specific environments and operative requirements, may be made to the described embodiments without departing from the spirit and scope of the present invention. Accordingly, it should be understood that the embodiments disclosed herein are merely illustrative of the principles of the invention. Various other modifications may be made by those skilled in the art which will embody the principles of the invention and fall within the spirit and the scope thereof.

Claims (33)

1. A bone stabilizing system for stabilizing first and second vertebrae in a spinal column comprising:
a plurality of bone screws having a threaded shaft and a head, the shaft having a longitudinal central axis;
a three dimensional body configured for insertion between the endplates of vertebrae, the three dimensional body having an upper surface for abutting the endplate of the first vertebrae, a lower surface for abutting the endplate of the second vertebrae, a front surface, and a horizontal center plane between the upper and lower surface; and
a front plate having a top surface and a bottom surface, the plate coupleable to the body such that the bottom surface is adjacent to and at least partially overlies the front surface, the plate having a plurality of screw holes for receiving the shafts of the screws, the screw holes extending through the plate and having a central axis, at least two screw holes extending through the plate at an angle such that the central axis of the screw hole ranges from about 25° to about 70° with respect to the horizontal center plane or a plane parallel to the horizontal center plane.
2. The system of claim 1, wherein the three dimensional body has a plurality of boreholes, the boreholes extending from the front surface to at least one of the upper surface and the lower surface.
3. The system of claim 2, wherein, when the plate is coupled to the three-dimensional body, the three-dimensional body and at least one of the angled screw holes in the front plate is configured and oriented such that one of the screws inserted into that angled screw hole pierces at least partially at least one of the upper surface and the lower surface of the three-dimensional body.
4. The system of claim 1, wherein, when the front plate is secured to the three-dimensional body, the central axis of at least one of the angled screw holes extends toward the upper surface of the three-dimensional body and the axis of at least one of the angled screw holes extends toward the lower surface of the three-dimensional body.
5. The system of claim 1, wherein the three-dimensional body is made from a non-metallic material.
6. The system of claim 5, wherein the front plate is formed of a metallic material.
7. The system of claim 1 wherein the front plate has a superior surface and an inferior surface and a height between the superior surface and the inferior surface and wherein the front surface of the three-dimensional body has a height between the upper surface and lower surface that is substantially equal to the height of the front plate.
8. The system of claim 1, wherein the first plate has a superior surface and an inferior surface and a height between the superior surface and the inferior surface and the three-dimensional body has a height between the upper surface and lower surface, wherein the maximum height of the three-dimensional body is substantially equal to or greater than the height of the front plate.
9. The system of claim 1, wherein the three-dimensional body further includes at least one borehole in communication with the front surface and one of the upper surface or the lower surface and the front plate is couplable with the three dimensional body so that at least one of the angled screw holes formed in the front plate aligns with the at least one borehole in the three-dimensional body so that one of the bone screws is insertable through the angled screw hole formed in the plate, through the recess formed in the three dimensional bodies and into one of the vertebrae.
10. The system of claim 1, wherein the three dimensional body includes at least one through hole extending from the upper surface to the lower surface.
11. The system of claim 1, wherein at least one of the angled screw holes formed in the front plate is conically shaped such that it tapers conically towards the front plate's bottom surface.
12. The system of claim 1, wherein one of the angled screw holes in the front plate includes internal threads, and at least a portion of the head of one of the bone screws has external threads for engaging the internal thread of the angled screw hole.
13. The system of claim 1, wherein at least one the angled screw holes in the front plate has internal threads and that threaded portion is conically tapered and wherein a plurality of the bone screws have at least a portion of their heads externally threaded.
14. The system of claim 1, wherein one of the upper and lower surfaces of the three-dimensional body is convex.
15. The system of claim 1, wherein the front plate has a plurality of angular screw holes and the three-dimensional body has a plurality of boreholes for alignment with the angular screw holes wherein the angular screw holes when aligned with the boreholes form passages for the screws that diverge as the passages extend away from the front surface into the three-dimensional body.
16. The system of claim 1, wherein the front plate has a plurality of angular screw holes and the three-dimensional body has a plurality of boreholes for alignment with the angular screw holes, wherein the angular screw holes when aligned with the boreholes form passages for the screws that are parallel as they extend away from the front surface into the three-dimensional body.
17. The system of claim 1, wherein the three dimensional body further has a convex left side surface, a convex right side surface and a back surface.
18. The system of claim 2, wherein the three-dimensional body further includes a left-side surface, a convex right side surface and a back surface, and the three-dimensional body does not have boreholes to receive screws that pass through either the left side or the right side.
19. The system of claim 1, wherein the three-dimensional body has angular boreholes that extend from the front face to at least one of the upper surface and the lower surface and the boreholes do not cross the horizontal plane.
20. A spine stabilizing system for stabilizing first and second vertebrae in a spinal column comprising:
a plurality of bone screws having a threaded shaft and a head, the shaft having a longitudinal central axis;
a three dimensional body formed of plastic configured for insertion between endplates of the first and second vertebrae, the three dimensional body having an upper surface for abutting the endplate of a first vertebrae, a lower surface for abutting the endplate of a second vertebrae, a front surface, and a horizontal center plane between the upper and lower surface; and
a front plate formed of a metallic material having a top surface, a bottom surface, a superior surface and an inferior surface, the plate couplable to the three dimensional body such that the bottom surface overlies the front surface, the plate having a plurality of screw holes for receiving there through the shaft of the screws, the screw holes having a central axis and extending through the plate at an angle such that the central axis of the screw hole ranges from about 25° to about 70° with respect to the horizontal center plane or a plane parallel to the horizontal center plane,
wherein a first angled screw hole is angled in the front plate toward the superior surface of the front plate and the second angled screw hole is angled in the front plate toward the inferior surface of the front plate.
21. The system of claim 20, wherein at least one of the angled screw holes includes internal threads.
22. The system of claim 20, wherein at least one of the screws includes external threading at least partially on its head.
23. The system of claim 20, wherein the height of the front plate is substantially equal to the height of the front surface of the three-dimensional body.
24. The system of claim 20, wherein the three dimensional body has a horizontal middle plane between the upper surface and the lower surface, and the front plate is coupleable to the three dimensional body such that the axis of at least two angled screw holes define an angle ranging from about 25° to about 70° with the horizontal middle plane.
25. A spine stabilizing system for stabilizing first and second vertebrae in a spinal column comprising:
a plurality of bone screws having a threaded shaft and a head, the shaft having a longitudinal central axis;
a three dimensional body configured for insertion between endplates of the first and second vertebrae, the three dimensional body having an upper surface for abutting the endplate of a first vertebrae, a lower surface for abutting the endplate of a second vertebrae, a left side surface and a right side surface, a front surface and a back surface, the three dimensional body having a horizontal central plane between the upper and lower surface, the three-dimensional body having a plurality of boreholes for receiving there through the screws, at least one borehole extending from the front surface to the upper surface of the three dimensional body and at least one borehole extending from the front surface to the lower surface of the three dimensional body, each borehole having a central axis wherein each central axis is at an angle in the range of about 25° to about 70° relative to the horizontal middle plane of the body.
26. The system of claim 25, wherein the plurality of bore holes are aligned in the front surface in a horizontal line.
27. The system of claim 25, further comprising:
a front plate having a top surface, a bottom surface, a superior surface and an inferior surface, the plate couplable to the three dimensional body such that the bottom surface overlies the front surface, the plate having a plurality of screw holes for receiving there through the shaft of the screws, the screw holes having a central axis, at least two of the plurality of screw holes extending through the front plate so that the axis of the screw hole is at an angle that is substantially equal to the angle of the boreholes in the three-dimensional body,
wherein the position and orientation of the front plate is such that the at least two angled boreholes in the three dimensional body are aligned with the at least two angled screw holes in the front plate so that the screws are insertable in the front plate so that its shaft extends out of respective upper and lower surfaces of the three-dimensional body.
28. The system of claim 27, wherein when the plate is coupled to the three-dimensional body, the three-dimensional body and at least one of the screw holes in the front plate are configured and oriented such that one of the screws inserted into the angled screw hole pierces at least partially one of the upper or lower surfaces of the three-dimensional body.
29. The system of claim 25, wherein the three dimensional body is formed of a non-metallic material.
30. The system of claim 25, wherein the three dimensional body includes at least one through hole extending from the upper surface to the lower surface.
31. The system of claim 27, wherein at least one of the angled screw holes formed in the front plate is conically shaped.
32. The system of claim 25, wherein one of the upper and lower surfaces of the three-dimensional body is convex.
33. The system of claim 25, wherein at least one of the upper surface and the lower surface includes one of the group of grooves, ribs, teeth and roughened surface portion to improve anchoring of the three-dimensional body with the vertebrae.
US13012626 2002-02-19 2011-01-24 Intervertebral implant Abandoned US20110118843A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
PCT/CH2002/000099 WO2003070128A8 (en) 2002-02-19 2002-02-19 Intervertebral implant
US10923534 US7232464B2 (en) 2002-02-19 2004-08-19 Intervertebral implant
US11751757 US7618456B2 (en) 2002-02-19 2007-05-22 Intervertebral implant
US12574222 US7875076B2 (en) 2002-02-19 2009-10-06 Intervertebral implant
US13012626 US20110118843A1 (en) 2002-02-19 2011-01-24 Intervertebral implant

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US13012626 US20110118843A1 (en) 2002-02-19 2011-01-24 Intervertebral implant
US13284762 US20120109313A1 (en) 2002-02-19 2011-10-28 Intervertebral Implant
US13284755 US20120109312A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284726 US20120109309A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284742 US20120101581A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284731 US20120109310A1 (en) 2002-02-19 2011-10-28 Intervertebral Implant
US13284747 US9572681B2 (en) 2002-02-19 2011-10-28 Intervertebral implant
US15401713 US20170143509A1 (en) 2002-02-19 2017-01-09 Intervertebral Implant

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US12574222 Continuation US7875076B2 (en) 2002-02-19 2009-10-06 Intervertebral implant

Related Child Applications (6)

Application Number Title Priority Date Filing Date
US13284762 Continuation US20120109313A1 (en) 2002-02-19 2011-10-28 Intervertebral Implant
US13284755 Continuation US20120109312A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284726 Continuation US20120109309A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284742 Continuation US20120101581A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284731 Continuation US20120109310A1 (en) 2002-02-19 2011-10-28 Intervertebral Implant
US13284747 Continuation US9572681B2 (en) 2002-02-19 2011-10-28 Intervertebral implant

Publications (1)

Publication Number Publication Date
US20110118843A1 true true US20110118843A1 (en) 2011-05-19

Family

ID=27740041

Family Applications (11)

Application Number Title Priority Date Filing Date
US10923534 Active US7232464B2 (en) 2002-02-19 2004-08-19 Intervertebral implant
US11751757 Active 2022-03-07 US7618456B2 (en) 2002-02-19 2007-05-22 Intervertebral implant
US12574222 Active US7875076B2 (en) 2002-02-19 2009-10-06 Intervertebral implant
US13012626 Abandoned US20110118843A1 (en) 2002-02-19 2011-01-24 Intervertebral implant
US13284747 Active US9572681B2 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284755 Abandoned US20120109312A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284731 Abandoned US20120109310A1 (en) 2002-02-19 2011-10-28 Intervertebral Implant
US13284726 Abandoned US20120109309A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284742 Abandoned US20120101581A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284762 Abandoned US20120109313A1 (en) 2002-02-19 2011-10-28 Intervertebral Implant
US15401713 Pending US20170143509A1 (en) 2002-02-19 2017-01-09 Intervertebral Implant

Family Applications Before (3)

Application Number Title Priority Date Filing Date
US10923534 Active US7232464B2 (en) 2002-02-19 2004-08-19 Intervertebral implant
US11751757 Active 2022-03-07 US7618456B2 (en) 2002-02-19 2007-05-22 Intervertebral implant
US12574222 Active US7875076B2 (en) 2002-02-19 2009-10-06 Intervertebral implant

Family Applications After (7)

Application Number Title Priority Date Filing Date
US13284747 Active US9572681B2 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284755 Abandoned US20120109312A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284731 Abandoned US20120109310A1 (en) 2002-02-19 2011-10-28 Intervertebral Implant
US13284726 Abandoned US20120109309A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284742 Abandoned US20120101581A1 (en) 2002-02-19 2011-10-28 Intervertebral implant
US13284762 Abandoned US20120109313A1 (en) 2002-02-19 2011-10-28 Intervertebral Implant
US15401713 Pending US20170143509A1 (en) 2002-02-19 2017-01-09 Intervertebral Implant

Country Status (9)

Country Link
US (11) US7232464B2 (en)
JP (1) JP4220395B2 (en)
KR (1) KR100882602B1 (en)
CN (1) CN100400014C (en)
CA (1) CA2478581C (en)
DE (1) DE50212036D1 (en)
EP (1) EP1476098B1 (en)
ES (1) ES2304428T3 (en)
WO (1) WO2003070128A8 (en)

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8257439B2 (en) 2004-12-22 2012-09-04 Ldr Medical Intervertebral disc prosthesis
US8267999B2 (en) 2002-11-05 2012-09-18 Ldr Medical Intervertebral disc prosthesis
US8343219B2 (en) 2007-06-08 2013-01-01 Ldr Medical Intersomatic cage, intervertebral prosthesis, anchoring device and implantation instruments
US8465546B2 (en) 2007-02-16 2013-06-18 Ldr Medical Intervertebral disc prosthesis insertion assemblies
US8771284B2 (en) 2005-11-30 2014-07-08 Ldr Medical Intervertebral disc prosthesis and instrumentation for insertion of the prosthesis between the vertebrae
US8858635B2 (en) 2004-02-04 2014-10-14 Ldr Medical Intervertebral disc prosthesis
US8974532B2 (en) 2004-04-28 2015-03-10 Ldr Medical Intervertebral disc prosthesis
US8979932B2 (en) 2005-09-23 2015-03-17 Ldr Medical Intervertebral disc prosthesis
US9005295B2 (en) 2007-11-16 2015-04-14 DePuy Synthes Products, LLC Low profile intervertebral implant
US9039774B2 (en) 2012-02-24 2015-05-26 Ldr Medical Anchoring device and system for an intervertebral implant, intervertebral implant and implantation instrument
US9039775B2 (en) 2003-03-31 2015-05-26 DePuy Synthes Products, Inc. Spinal fixation plates
US9044337B2 (en) 2009-12-31 2015-06-02 Ldr Medical Anchoring device and system for an intervertebral implant, intervertebral implant and implantation instrument
US9078765B2 (en) 2001-07-13 2015-07-14 Ldr Medical Vertebral cage device with modular fixation
US9192419B2 (en) 2008-11-07 2015-11-24 DePuy Synthes Products, Inc. Zero-profile interbody spacer and coupled plate assembly
US9220604B2 (en) 2010-12-21 2015-12-29 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
US9241809B2 (en) 2010-12-21 2016-01-26 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
US9333095B2 (en) 2001-05-04 2016-05-10 Ldr Medical Intervertebral disc prosthesis, surgical methods, and fitting tools
US9463091B2 (en) 2009-09-17 2016-10-11 Ldr Medical Intervertebral implant having extendable bone fixation members
US9463097B2 (en) 2003-02-06 2016-10-11 DePuy Synthes Products, Inc. Intervertebral implant
US9526620B2 (en) 2009-03-30 2016-12-27 DePuy Synthes Products, Inc. Zero profile spinal fusion cage
US9539043B2 (en) 2013-03-13 2017-01-10 Ebi, Llc Screw driver, combination, and related methods
US9572681B2 (en) 2002-02-19 2017-02-21 DePuy Synthes Products, Inc. Intervertebral implant
US9693876B1 (en) * 2012-03-30 2017-07-04 Ali H. MESIWALA Spinal fusion implant and related methods
US9713535B2 (en) 2006-02-15 2017-07-25 Ldr Medical Transforaminal intersomatic cage for an intervertebral fusion graft and an instrument for implanting the cage
US9867718B2 (en) 2014-10-22 2018-01-16 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
US9877842B2 (en) 2014-01-30 2018-01-30 Ldr Medical Anchoring device for a spinal implant, spinal implant and implantation instrumentation

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6206922B1 (en) * 1995-03-27 2001-03-27 Sdgi Holdings, Inc. Methods and instruments for interbody fusion
US8613772B2 (en) * 2003-04-21 2013-12-24 Rsb Spine Llc Lateral mount implant device
US20170020683A1 (en) * 2003-04-21 2017-01-26 Rsb Spine Llc Bone plate stabilization system and method for its use
US7985255B2 (en) * 2003-04-21 2011-07-26 Rsb Spine Llc Implant subsidence control
US9278009B2 (en) * 2003-04-21 2016-03-08 Rsb Spine Llc Spine implants
US8100976B2 (en) * 2003-04-21 2012-01-24 Rsb Spine Llc Implant subsidence control
US8496708B2 (en) 2005-03-17 2013-07-30 Spinal Elements, Inc. Flanged interbody fusion device with hinge
US9744052B2 (en) 2005-04-12 2017-08-29 Nathan C. Moskowitz Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs
US7942903B2 (en) 2005-04-12 2011-05-17 Moskowitz Ahmnon D Bi-directional fixating transvertebral body screws and posterior cervical and lumbar interarticulating joint calibrated stapling devices for spinal fusion
US9814601B2 (en) 2005-04-12 2017-11-14 Nathan C. Moskowitz Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs
US7972363B2 (en) 2005-04-12 2011-07-05 Moskowitz Ahmnon D Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs and posterior cervical and lumbar interarticulating joint stapling guns and devices for spinal fusion
US9532821B2 (en) 2005-04-12 2017-01-03 Nathan C. Moskowitz Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs with vertical hemi-bracket screw locking mechanism
US9848993B2 (en) 2005-04-12 2017-12-26 Nathan C. Moskowitz Zero-profile expandable intervertebral spacer devices for distraction and spinal fusion and a universal tool for their placement and expansion
US7754906B2 (en) 2005-10-07 2010-07-13 Air Products And Chemicals, Inc. Ti, Ta, Hf, Zr and related metal silicon amides for ALD/CVD of metal-silicon nitrides, oxides or oxynitrides
US7887595B1 (en) 2005-12-05 2011-02-15 Nuvasive, Inc. Methods and apparatus for spinal fusion
WO2007075411A3 (en) * 2005-12-16 2008-11-06 Nicholas M Cordaro An intervertebral prosthesis for supporting adjacent vertebral bodies enabling the creation of soft fusion and method
EP1988855A2 (en) * 2006-02-27 2008-11-12 Synthes GmbH Intervertebral implant with fixation geometry
US8114162B1 (en) 2006-08-09 2012-02-14 Nuvasive, Inc. Spinal fusion implant and related methods
USD708747S1 (en) 2006-09-25 2014-07-08 Nuvasive, Inc. Spinal fusion implant
US8425607B2 (en) * 2007-04-03 2013-04-23 Warsaw Orthopedic, Inc. Anchor member locking features
US8268000B2 (en) * 2007-04-03 2012-09-18 Warsaw Orthopedic, Inc. Composite interbody spacer
EP2142146A4 (en) * 2007-05-01 2010-12-01 Spinal Simplicity Llc Interspinous implants and methods for implanting same
US8142479B2 (en) * 2007-05-01 2012-03-27 Spinal Simplicity Llc Interspinous process implants having deployable engagement arms
JP5226066B2 (en) 2007-05-01 2013-07-03 スパイナル シンプリシティ エルエルシーSpinal Simplicity LLC Interspinous implants and methods for embedding it
ES2387506T3 (en) * 2007-07-26 2012-09-25 Biedermann Technologies Gmbh & Co. Kg Bone fixation device
US8852280B2 (en) 2007-09-27 2014-10-07 Warsaw Orthopedic, Inc. Intervertebral implant
US8414651B2 (en) * 2008-01-16 2013-04-09 Aesculap Implant Systems, Llc Dynamic interbody
US8377132B2 (en) * 2008-01-16 2013-02-19 Aesculap Implant Systems, Llc Standalone dynamic interbody
US8167949B2 (en) * 2008-01-25 2012-05-01 Aesculap Implant Systems, Llc Hydrostatic interbody
GB0803074D0 (en) * 2008-02-20 2008-03-26 Surgicraft Ltd Orthopaedic implants and prostheses
US8267939B2 (en) 2008-02-28 2012-09-18 Stryker Spine Tool for implanting expandable intervertebral implant
US20090248092A1 (en) 2008-03-26 2009-10-01 Jonathan Bellas Posterior Intervertebral Disc Inserter and Expansion Techniques
US8333804B1 (en) 2008-03-27 2012-12-18 Spinelogik, Inc. Intervertebral fusion device and method of use
US8313528B1 (en) 2008-03-27 2012-11-20 Spinelogik, Inc. Intervertebral fusion device and method of use
WO2009124291A3 (en) * 2008-04-04 2010-01-21 Thomas Haider Patents Intervertebral prostheses with compliant filler material for supporting adjacent vertebral bodies and method
WO2009149371A1 (en) 2008-06-05 2009-12-10 Synthes Usa, Llc Articulating disc implant
US8328872B2 (en) 2008-09-02 2012-12-11 Globus Medical, Inc. Intervertebral fusion implant
US8137405B2 (en) * 2008-10-08 2012-03-20 K2M, Inc. Spinal interbody spacer
US8182539B2 (en) * 2008-10-23 2012-05-22 Aesculap Implant Systems, Llc Dynamic interbody with motion control mechanisms
US9060808B2 (en) 2008-12-05 2015-06-23 DePuy Synthes Products, Inc. Anchor-in-anchor system for use in bone fixation
JP5759900B2 (en) 2008-12-05 2015-08-05 ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング Anchor-in-anchor system for use in bone fixation
US20100161057A1 (en) * 2008-12-19 2010-06-24 Amicus, Llc Interbody Vertebral Prosthetic Device With Self-Deploying Screws
US8968405B2 (en) * 2009-01-20 2015-03-03 Incite Innovation Llc Interbody fusion device and method of operation
US8187329B2 (en) * 2009-02-20 2012-05-29 Spartan Cage Holding, Llc Interbody fusion system with intervertebral implant retention assembly
US9220609B2 (en) * 2009-02-25 2015-12-29 Spinewelding Ag Spine stabilization device, and method and kit for its implantation
US9861399B2 (en) 2009-03-13 2018-01-09 Spinal Simplicity, Llc Interspinous process implant having a body with a removable end portion
US8945184B2 (en) * 2009-03-13 2015-02-03 Spinal Simplicity Llc. Interspinous process implant and fusion cage spacer
US9220547B2 (en) 2009-03-27 2015-12-29 Spinal Elements, Inc. Flanged interbody fusion device
US8641766B2 (en) 2009-04-15 2014-02-04 DePuy Synthes Products, LLC Arcuate fixation member
US9408715B2 (en) * 2009-04-15 2016-08-09 DePuy Synthes Products, Inc. Arcuate fixation member
WO2010137110A1 (en) * 2009-05-26 2010-12-02 株式会社湊川金属テストピース製作所 Intervertebral implant
US8709083B2 (en) 2009-06-04 2014-04-29 William E. Duffield Intervertebral fusion implant
US8920471B2 (en) 2010-07-12 2014-12-30 K2M, Inc. Transverse connector
US8343223B2 (en) * 2009-07-14 2013-01-01 Life Spine, Inc. Combined spinal interbody and plate assemblies
US9095444B2 (en) 2009-07-24 2015-08-04 Warsaw Orthopedic, Inc. Implant with an interference fit fastener
KR101041387B1 (en) 2009-07-27 2011-06-15 주식회사 코렌텍 A Cage for ALIFAnterior Lumbar Interbody Fusion and The set thereof
US8641765B2 (en) * 2009-08-12 2014-02-04 Nabil L. Muhanna Posterior spinal implant system
US9730804B2 (en) 2009-09-06 2017-08-15 Warsaw Orthopedic, Inc. Locking spinal fusion device
US9066815B2 (en) 2009-11-09 2015-06-30 Centinel Spine, Inc. Spinal implant with attachment system
EP2498723B1 (en) 2009-11-09 2017-11-01 Centinel Spine Inc. Spinal implant configured for lateral insertion
US8740983B1 (en) 2009-11-11 2014-06-03 Nuvasive, Inc. Spinal fusion implants and related methods
US8840668B1 (en) 2009-11-11 2014-09-23 Nuvasive, Inc. Spinal implants, instruments and related methods
US8764806B2 (en) 2009-12-07 2014-07-01 Samy Abdou Devices and methods for minimally invasive spinal stabilization and instrumentation
US8945226B2 (en) * 2009-12-31 2015-02-03 Rhausler Vertebral spacer
US9408718B2 (en) * 2009-12-31 2016-08-09 Rhausler, Inc. Inter-vertebral implant with angled plate
US8945227B2 (en) * 2010-02-01 2015-02-03 X-Spine Systems, Inc. Spinal implant co-insertion system and method
US9427324B1 (en) 2010-02-22 2016-08-30 Spinelogik, Inc. Intervertebral fusion device and method of use
EP2361572B1 (en) * 2010-02-26 2013-04-17 Biedermann Technologies GmbH & Co. KG Implant for stabilizing bones or vertebrae
WO2011116368A1 (en) 2010-03-19 2011-09-22 K2M, Inc. Anterior bracket for spinal fixation
US8647369B2 (en) 2010-05-19 2014-02-11 Josef E. Gorek Minimal profile anterior bracket for spinal fixation
EP2579793B1 (en) * 2010-06-09 2015-09-16 Synthes GmbH Anchor-in-anchor system for use in bone fixation
US8377139B2 (en) 2010-06-17 2013-02-19 Aesculap Implant Systems, Llc Standalone interbody fusion device with locking and release mechanism
US8480747B2 (en) 2010-08-11 2013-07-09 Warsaw Orthopedic, Inc. Interbody spinal implants with extravertebral support plates
US8956415B2 (en) 2010-08-15 2015-02-17 Warsaw Orthopedic, Inc. Vertebral implant
US9351848B2 (en) 2010-09-03 2016-05-31 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US9566168B2 (en) 2010-09-03 2017-02-14 Globus Medical, Inc. Expandable fusion device and method of installation thereof
US8753396B1 (en) 2010-09-13 2014-06-17 Theken Spine, Llc Intervertebral implant having back-out prevention feature
US20120078372A1 (en) * 2010-09-23 2012-03-29 Thomas Gamache Novel implant inserter having a laterally-extending dovetail engagement feature
US9468535B2 (en) 2010-12-17 2016-10-18 K2M, Inc. Interbody spacer
US9358122B2 (en) 2011-01-07 2016-06-07 K2M, Inc. Interbody spacer
WO2012099852A1 (en) 2011-01-17 2012-07-26 Cibor, Inc. Reinforced carbon fiber/carbon foam intervertebral spine fusion device
US20120197401A1 (en) * 2011-01-27 2012-08-02 Warsaw Orthopedic, Inc. Interbody spinal implants with modular add-on devices
US8940030B1 (en) 2011-01-28 2015-01-27 Nuvasive, Inc. Spinal fixation system and related methods
US8454694B2 (en) 2011-03-03 2013-06-04 Warsaw Orthopedic, Inc. Interbody device and plate for spinal stabilization and instruments for positioning same
US20120232599A1 (en) * 2011-03-10 2012-09-13 Jared Schoenly Awl screw fixation members and related systems
US20120245693A1 (en) * 2011-03-25 2012-09-27 Josef Gorek Spinal fixation device
US9005292B2 (en) * 2011-05-10 2015-04-14 Hooman M. MELAMED Vertebral spacer
JP6047571B2 (en) 2011-08-16 2016-12-21 ストライカー・スピン Expandable graft
US9381048B2 (en) 2011-08-31 2016-07-05 DePuy Synthes Products, Inc. Devices and methods for cervical lateral fixation
US9277946B2 (en) 2011-09-06 2016-03-08 Amendia, Inc. Spinal fusion system
US9539109B2 (en) 2011-09-16 2017-01-10 Globus Medical, Inc. Low profile plate
US9681959B2 (en) 2011-09-16 2017-06-20 Globus Medical, Inc. Low profile plate
US9248028B2 (en) 2011-09-16 2016-02-02 DePuy Synthes Products, Inc. Removable, bone-securing cover plate for intervertebral fusion cage
US9237957B2 (en) 2011-09-16 2016-01-19 Globus Medical, Inc. Low profile plate
US9848994B2 (en) 2011-09-16 2017-12-26 Globus Medical, Inc. Low profile plate
US8460388B2 (en) 2011-10-28 2013-06-11 Incite Innovation Llc Spinal interbody device
US9198764B2 (en) 2012-01-31 2015-12-01 Blackstone Medical, Inc. Intervertebral disc prosthesis and method
EP2628466B1 (en) 2012-02-17 2017-04-05 Medacta International S.A. Intervertebral implant with improved fastening system for the fixing plate
US9271836B2 (en) 2012-03-06 2016-03-01 DePuy Synthes Products, Inc. Nubbed plate
US9566165B2 (en) 2012-03-19 2017-02-14 Amicus Design Group, Llc Interbody vertebral prosthetic and orthopedic fusion device with self-deploying anchors
JP5913727B2 (en) 2012-03-19 2016-04-27 アミカス デザイン グループ、エルエルシー Interbody spinal prosthetic shaping fixing device using a self-extracting anchor
US8814912B2 (en) 2012-07-27 2014-08-26 Zimmer Spine, Inc. Bone stabilization member with bone screw retention mechanism
US9326861B2 (en) 2012-08-03 2016-05-03 Globus Medical, Inc. Stabilizing joints
US9387021B2 (en) * 2012-08-20 2016-07-12 Ebi, Llc Implant with semi-enclosed screws
CA2882601A1 (en) 2012-08-22 2014-02-27 Andreas Appenzeller Anchor-in-anchor system
US9414868B1 (en) 2012-12-13 2016-08-16 Spinelogik, Inc. Guide placement device and method of use
US9757164B2 (en) 2013-01-07 2017-09-12 Spinal Simplicity Llc Interspinous process implant having deployable anchor blades
US20140200672A1 (en) * 2013-01-17 2014-07-17 Stryker Spine Annulus plug for intervertebral disc repair
US9572680B2 (en) 2013-01-25 2017-02-21 K2M, Inc. Spinal implants, spinal implant kits, and surgical methods
US9585765B2 (en) 2013-02-14 2017-03-07 Globus Medical, Inc Devices and methods for correcting vertebral misalignment
US9402738B2 (en) 2013-02-14 2016-08-02 Globus Medical, Inc. Devices and methods for correcting vertebral misalignment
US9782265B2 (en) 2013-02-15 2017-10-10 Globus Medical, Inc Articulating and expandable vertebral implant
US9204972B2 (en) 2013-03-01 2015-12-08 Globus Medical, Inc. Articulating expandable intervertebral implant
US9149365B2 (en) 2013-03-05 2015-10-06 Globus Medical, Inc. Low profile plate
US9707096B2 (en) 2013-03-14 2017-07-18 K2M, Inc. Spinal fixation device
US9456906B2 (en) 2013-03-15 2016-10-04 Globus Medical, Inc. Expandable intervertebral implant
US9474622B2 (en) 2013-03-15 2016-10-25 Globus Medical, Inc Expandable intervertebral implant
US9539103B2 (en) 2013-03-15 2017-01-10 Globus Medical, Inc. Expandable intervertebral implant
US9149367B2 (en) 2013-03-15 2015-10-06 Globus Medical Inc Expandable intervertebral implant
US9186258B2 (en) 2013-03-15 2015-11-17 Globus Medical, Inc. Expandable intervertebral implant
US9034045B2 (en) 2013-03-15 2015-05-19 Globus Medical, Inc Expandable intervertebral implant
CN103393487A (en) * 2013-07-16 2013-11-20 江苏双羊医疗器械有限公司 Interbody fusion apparatus
USD745159S1 (en) 2013-10-10 2015-12-08 Nuvasive, Inc. Intervertebral implant
US9402739B2 (en) 2014-02-07 2016-08-02 Globus Medical, Inc. Variable lordosis spacer and related methods of use
US9486327B2 (en) 2014-05-15 2016-11-08 Globus Medical, Inc. Standalone interbody implants
US9675465B2 (en) 2014-05-15 2017-06-13 Globus Medical, Inc. Standalone interbody implants
US9545320B2 (en) 2014-05-15 2017-01-17 Globus Medical, Inc. Standalone interbody implants

Citations (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4135506A (en) * 1976-03-16 1979-01-23 Ulrich Max B Method of and device for pinning a fractured vertebra
US4501269A (en) * 1981-12-11 1985-02-26 Washington State University Research Foundation, Inc. Process for fusing bone joints
US4503848A (en) * 1981-04-08 1985-03-12 Aesculap-Werke Aktiengesellschaft Osteosynthesis plate
US4512038A (en) * 1979-04-27 1985-04-23 University Of Medicine And Dentistry Of New Jersey Bio-absorbable composite tissue scaffold
US4717115A (en) * 1986-10-14 1988-01-05 The United States Of America As Represented By The Secretary Of The Army Adjustable mold for fabricating bone replacements
US4904261A (en) * 1987-08-06 1990-02-27 A. W. Showell (Surgicraft) Limited Spinal implants
US4994084A (en) * 1989-06-23 1991-02-19 Brennan H George Reconstructive surgery method and implant
US5084051A (en) * 1986-11-03 1992-01-28 Toermaelae Pertti Layered surgical biocomposite material
US5085660A (en) * 1990-11-19 1992-02-04 Lin Kwan C Innovative locking plate system
US5108438A (en) * 1989-03-02 1992-04-28 Regen Corporation Prosthetic intervertebral disc
US5180381A (en) * 1991-09-24 1993-01-19 Aust Gilbert M Anterior lumbar/cervical bicortical compression plate
US5192327A (en) * 1991-03-22 1993-03-09 Brantigan John W Surgical prosthetic implant for vertebrae
US5275601A (en) * 1991-09-03 1994-01-04 Synthes (U.S.A) Self-locking resorbable screws and plates for internal fixation of bone fractures and tendon-to-bone attachment
US5281226A (en) * 1989-03-31 1994-01-25 Davydov Anatoly B Missing portion of a tubular bone
US5284655A (en) * 1989-09-21 1994-02-08 Osteotech, Inc. Swollen demineralized bone particles, flowable osteogenic composition containing same and use of the composition in the repair of osseous defects
US5290312A (en) * 1991-09-03 1994-03-01 Alphatec Artificial vertebral body
US5397364A (en) * 1993-10-12 1995-03-14 Danek Medical, Inc. Anterior interbody fusion device
US5405391A (en) * 1993-02-16 1995-04-11 Hednerson; Fraser C. Fusion stabilization chamber
US5489308A (en) * 1989-07-06 1996-02-06 Spine-Tech, Inc. Spinal implant
US5507818A (en) * 1994-06-30 1996-04-16 Mclaughlin; John A. Multipolar joint endoprosthesis
US5593409A (en) * 1988-06-13 1997-01-14 Sofamor Danek Group, Inc. Interbody spinal fusion implants
US5601553A (en) * 1994-10-03 1997-02-11 Synthes (U.S.A.) Locking plate and bone screw
US5607474A (en) * 1992-02-14 1997-03-04 Board Of Regents, University Of Texas System Multi-phase bioerodible implant/carrier and method of manufacturing and using same
US5609636A (en) * 1994-05-23 1997-03-11 Spine-Tech, Inc. Spinal implant
US5609635A (en) * 1988-06-28 1997-03-11 Michelson; Gary K. Lordotic interbody spinal fusion implants
US5609637A (en) * 1993-07-09 1997-03-11 Biedermann; Lutz Space keeper, in particular for an intervertebral disk
US5616144A (en) * 1992-11-25 1997-04-01 Codman & Shurtleff, Inc. Osteosynthesis plate system
US5713899A (en) * 1995-04-27 1998-02-03 Societe Jbs Sa Cervical cage designed for the performance of intersomatic arthrodesis
US5728159A (en) * 1997-01-02 1998-03-17 Musculoskeletal Transplant Foundation Serrated bone graft
US5735905A (en) * 1995-04-27 1998-04-07 Southwest Research Institute Shock absorbing element for a load bearing prosthesis
US5861041A (en) * 1997-04-07 1999-01-19 Arthit Sitiso Intervertebral disk prosthesis and method of making the same
US5865845A (en) * 1996-03-05 1999-02-02 Thalgott; John S. Prosthetic intervertebral disc
US5865849A (en) * 1995-06-07 1999-02-02 Crosscart, Inc. Meniscal heterografts
US5872915A (en) * 1996-12-23 1999-02-16 International Business Machines Corporation Computer apparatus and method for providing security checking for software applications accessed via the World-Wide Web
US5876402A (en) * 1995-04-13 1999-03-02 Errico; Joseph P. Anterior spinal polyaxial locking screw plate assembly having recessed retaining rings
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
US5885299A (en) * 1994-09-15 1999-03-23 Surgical Dynamics, Inc. Apparatus and method for implant insertion
US5888227A (en) * 1995-10-20 1999-03-30 Synthes (U.S.A.) Inter-vertebral implant
US5888222A (en) * 1995-10-16 1999-03-30 Sdgi Holding, Inc. Intervertebral spacers
US5888223A (en) * 1995-12-08 1999-03-30 Bray, Jr.; Robert S. Anterior stabilization device
US5888224A (en) * 1993-09-21 1999-03-30 Synthesis (U.S.A.) Implant for intervertebral space
US5895426A (en) * 1996-09-06 1999-04-20 Osteotech, Inc. Fusion implant device and method of use
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US6025538A (en) * 1998-11-20 2000-02-15 Musculoskeletal Transplant Foundation Compound bone structure fabricated from allograft tissue
US6033405A (en) * 1994-09-15 2000-03-07 Surgical Dynamics, Inc. Apparatus and method for implant insertion
US6033438A (en) * 1997-06-03 2000-03-07 Sdgi Holdings, Inc. Open intervertebral spacer
US6039762A (en) * 1995-06-07 2000-03-21 Sdgi Holdings, Inc. Reinforced bone graft substitutes
US6045579A (en) * 1997-05-01 2000-04-04 Spinal Concepts, Inc. Adjustable height fusion device
US6193756B1 (en) * 1997-09-30 2001-02-27 Sulzer Orthopaedie Ag Tubular support body for bridging two vertebrae
US6193721B1 (en) * 1997-02-11 2001-02-27 Gary K. Michelson Multi-lock anterior cervical plating system
US6200347B1 (en) * 1999-01-05 2001-03-13 Lifenet Composite bone graft, method of making and using same
US6206922B1 (en) * 1995-03-27 2001-03-27 Sdgi Holdings, Inc. Methods and instruments for interbody fusion
US20020004683A1 (en) * 2000-07-10 2002-01-10 Michelson Gary K. Flanged interbody spinal fusion implants
US20020010511A1 (en) * 2000-07-07 2002-01-24 Michelson Gary Karlin Expandable implant with interlocking walls
US6342074B1 (en) * 1999-04-30 2002-01-29 Nathan S. Simpson Anterior lumbar interbody fusion implant and method for fusing adjacent vertebrae
US20020016595A1 (en) * 1999-05-05 2002-02-07 Gary K. Michelson Screws of cortical bone and method of manufacture thereof
US20020029084A1 (en) * 1998-08-03 2002-03-07 Paul David C. Bone implants with central chambers
US6364880B1 (en) * 1994-03-28 2002-04-02 Gary Karlin Michelson Spinal implant with bone screws
US6371986B1 (en) * 1998-10-27 2002-04-16 George W. Bagby Spinal fusion device, bone joining implant, and vertebral fusion implant
US6503250B2 (en) * 2000-11-28 2003-01-07 Kamaljit S. Paul Bone support assembly
US6524312B2 (en) * 2000-01-06 2003-02-25 Spinal Concepts, Inc. Instrument and method for implanting an interbody fusion device
US20030078668A1 (en) * 1999-05-05 2003-04-24 Michelson Gary K. Interbody spinal fusion implants with single-lock for locking opposed screws
US20030078666A1 (en) * 2001-10-18 2003-04-24 Ralph James D. Intervertebral spacer device having a slotted partial circular domed arch strip spring
US6679887B2 (en) * 1998-05-06 2004-01-20 Cortek, Inc. Surgical procedure for implanting spinal fusion device
US6682563B2 (en) * 2002-03-04 2004-01-27 Michael S. Scharf Spinal fixation device
US6695846B2 (en) * 2002-03-12 2004-02-24 Spinal Innovations, Llc Bone plate and screw retaining mechanism
US6709456B2 (en) * 2000-01-31 2004-03-23 Ev3 Santa Rosa, Inc. Percutaneous mitral annuloplasty with hemodynamic monitoring
US20040078078A1 (en) * 2002-10-18 2004-04-22 Shepard Yolanda Denise Cortical and cancellous allograft cervical fusion block
US20040078081A1 (en) * 2002-09-09 2004-04-22 Ferree Bret A. Bioresorbable components and methods for spinal arthroplasty
US6837905B1 (en) * 2002-09-26 2005-01-04 Daniel M. Lieberman Spinal vertebral fusion implant and method
US20050015149A1 (en) * 2001-02-04 2005-01-20 Michelson Gary K. Instrumentation with inwardly moveable extensions for inserting an expandable interbody spinal fusion implant
US20050021143A1 (en) * 2003-07-22 2005-01-27 Cervitech, Inc. Intervertebral disc prosthesis
US6849093B2 (en) * 2001-03-09 2005-02-01 Gary K. Michelson Expansion constraining member adapted for use with an expandable interbody spinal fusion implant and method for use thereof
US6855168B2 (en) * 1997-04-25 2005-02-15 Stryker France Intersomatic implants in two parts
US20050049595A1 (en) * 2003-09-03 2005-03-03 Suh Sean S. Track-plate carriage system
US20050049593A1 (en) * 2003-09-03 2005-03-03 Duong Lan Anh Nguyen Bone plate with captive clips
US20050065608A1 (en) * 2000-02-04 2005-03-24 Michelson Gary K. Expandable threaded arcuate interbody spinal fusion implant with lordotic configuration during insertion
US20050071008A1 (en) * 2003-09-30 2005-03-31 Kirschman David Louis Spinal fusion system and method for fusing spinal bones
US20050085913A1 (en) * 2003-03-31 2005-04-21 Robert Fraser Spinal fixation plate
US6984234B2 (en) * 2003-04-21 2006-01-10 Rsb Spine Llc Bone plate stabilization system and method for its use
US20060030851A1 (en) * 2003-04-21 2006-02-09 Rsb Spine Llc Implant subsidence control
US7001432B2 (en) * 2002-03-12 2006-02-21 Cervitech, Inc. Intervertebral prosthesis
US7001385B2 (en) * 1998-08-20 2006-02-21 Bonutti Ip, Llc Joint spacer with compartment for orthobiologic material
US7172672B2 (en) * 2000-11-20 2007-02-06 Silverbrook Research Pty Ltd Method of adhesively binding a stack of sheets
US7172627B2 (en) * 2001-04-03 2007-02-06 Scient'x Stabilized interbody fusion system for vertebrae
US7238203B2 (en) * 2001-12-12 2007-07-03 Vita Special Purpose Corporation Bioactive spinal implants and method of manufacture thereof
US7320708B1 (en) * 2002-11-13 2008-01-22 Sdgi Holdings, Inc. Cervical interbody device
US20080051890A1 (en) * 2006-08-11 2008-02-28 Warsaw Orthopedic, Inc. Intervertebral Implants with Attachable Flanges and Methods of Use
US20090076608A1 (en) * 2007-09-17 2009-03-19 Vermillion Technologies, Llc Intervertebral disc replacement prosthesis
US20100016901A1 (en) * 2005-06-16 2010-01-21 Robinson James C Bone screw retaining system
US7862616B2 (en) * 2003-02-06 2011-01-04 Synthes Usa, Llc Intervertebral implant
US7875076B2 (en) * 2002-02-19 2011-01-25 Synthes Usa, Llc Intervertebral implant
US8343222B2 (en) * 2005-04-28 2013-01-01 Aiden Cope Spinal disc prosthesis and instruments

Family Cites Families (405)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US424836A (en) 1890-04-01 Nut-lock
US1105105A (en) 1912-02-10 1914-07-28 William O'n Sherman Surgical appliance.
US1200797A (en) 1915-09-30 1916-10-10 David Barbe Nut-lock.
GB157668A (en) 1920-04-14 1921-01-27 John Horsfall Improvements in and relating to nut locks
GB265592A (en) 1926-02-05 1927-08-18 Lorenz Hayd Improvements in nut locks
US2151919A (en) 1935-03-25 1939-03-28 Illinois Tool Works Locking device
US2372888A (en) 1944-04-20 1945-04-03 Duggan James Edward Nut structure
US2621145A (en) 1949-08-17 1952-12-09 Machteld E Sano Bone mat compositions
US2782827A (en) 1953-06-12 1957-02-26 Rosan Joseph Snap ring connection between threaded fastener and locking collar
US2906311A (en) 1956-11-01 1959-09-29 Illinois Tool Works Stud carried locking detents with means to hold the detents in lock position
US2972367A (en) 1957-07-18 1961-02-21 United Carr Fastener Corp Fastening device
US3062253A (en) 1958-08-26 1962-11-06 Waldes Kohinoor Inc Bolt and shear sleeve with shear sleeve retracting means
US3272249A (en) 1963-09-09 1966-09-13 Slater Steel Ind Ltd Locking device for use on suspension clamps and the like
US3350103A (en) 1965-08-02 1967-10-31 Ventura Tool Company Seal ring holding device
US3426364A (en) 1966-08-25 1969-02-11 Colorado State Univ Research F Prosthetic appliance for replacing one or more natural vertebrae
US3579831A (en) 1969-03-05 1971-05-25 Irving J Stevens Bone implant
US3810703A (en) 1969-06-20 1974-05-14 M Pasbrig Releasable joints with male and female elements
US3561075A (en) 1969-07-15 1971-02-09 Motorola Inc Threaded fastener captivating device
CA992255A (en) 1971-01-25 1976-07-06 Cutter Laboratories Prosthesis for spinal repair
US3707303A (en) 1971-03-10 1972-12-26 Petri Johnson Inc Means for securing an insert to a base piece
US3899897A (en) 1974-04-03 1975-08-19 Ford Motor Co By-pass suction throttling valve in a refrigeration system
US3945671A (en) 1974-10-23 1976-03-23 Emhart Corporation Seal lock and the like incorporating permanently secured single engagement
US4017946A (en) 1976-03-01 1977-04-19 Alta Engineering, Inc. Lock screw for rigging connector or the like
US4056301A (en) 1976-03-11 1977-11-01 Norden Alexander Retained screw assembly
GB1493220A (en) 1976-10-12 1977-11-30 Pye Ltd Screw or nut and a washer intended to be held captive thereon
US4285377A (en) 1977-03-28 1981-08-25 Hi-Shear Corporation Safety bolt
JPS6224784B2 (en) 1977-07-26 1987-05-29 Canon Kk
DE2747994A1 (en) 1977-10-26 1979-05-03 Kraftwerk Union Ag Rotation for the cylinder head bolts with polygonal socket or tool to plastically deform for such an anti-rotation
DE2821678C3 (en) 1978-05-12 1981-01-08 Gebrueder Sulzer Ag, Winterthur (Schweiz)
US4278120A (en) 1978-10-05 1981-07-14 Hi Shear Corporation Safety bolt
US4297063A (en) 1979-06-11 1981-10-27 Hi Shear Corporation Telescoping self-retaining safety bolt assembly
US4288902A (en) 1979-10-05 1981-09-15 Franz Louis J Method of forming a notched edge lock screw
GB2068734B (en) 1980-02-06 1983-11-23 Saratov Nii Travmatol I Ortope Hip endoprosthesis
DE3027148C2 (en) 1980-05-28 1982-05-27 Institut Straumann Ag, Waldenburg, Ch
DE3027138C2 (en) 1980-05-28 1983-01-27 Institut Straumann Ag, Waldenburg, Ch
CA1146301A (en) 1980-06-13 1983-05-17 J. David Kuntz Intervertebral disc prosthesis
DE3042003A1 (en) 1980-10-10 1982-07-15 Hans Dr Reimer Bone cement reinforcing component - comprises thread structure compatible with body tissue forming soft sponge
DE8105177U1 (en) 1981-02-25 1984-01-12 Schuett Und Grundei Gmbh Medizintechnische Fabrikation, 2400 Luebeck, De
US4394370A (en) 1981-09-21 1983-07-19 Jefferies Steven R Bone graft material for osseous defects and method of making same
US4450591A (en) 1981-12-10 1984-05-29 Rappaport Mark J Internal anti-proratory plug assembly and process of installing the same
FR2519857B1 (en) 1982-01-19 1984-03-23 Butel Jean
US4553890A (en) 1982-06-14 1985-11-19 Bulent Gulistan Captive panel screw
US4545374A (en) 1982-09-03 1985-10-08 Jacobson Robert E Method and instruments for performing a percutaneous lumbar diskectomy
GB2148122B (en) 1983-09-30 1986-10-22 Gendler El Process for stimulating induction of bone formation and stimulation of bone regeneration by artificially perforated bone matrix
DE8410539U1 (en) 1984-04-04 1985-05-02 Marker Patentverwertungsgesellschaft Mbh, Baar, Ch
US4648768A (en) 1984-05-15 1987-03-10 Hambric James C Locknut assembly for high-speed rotary components
FR2570594B1 (en) 1984-09-26 1989-02-24 Kehr Pierre Spinal prosthesis, particularly for cervical vertebrae
US5096150A (en) 1984-11-29 1992-03-17 Westwood Samuel M Clamp device
US5053049A (en) 1985-05-29 1991-10-01 Baxter International Flexible prostheses of predetermined shapes and process for making same
US4678470A (en) 1985-05-29 1987-07-07 American Hospital Supply Corporation Bone-grafting material
US4627853A (en) 1985-05-29 1986-12-09 American Hospital Supply Corporation Method of producing prostheses for replacement of articular cartilage and prostheses so produced
US4599086A (en) 1985-06-07 1986-07-08 Doty James R Spine stabilization device and method
US4743256A (en) 1985-10-04 1988-05-10 Brantigan John W Surgical prosthetic implant facilitating vertebral interbody fusion and method
US4834757A (en) 1987-01-22 1989-05-30 Brantigan John W Prosthetic implant
EP0230937B1 (en) 1986-01-28 1990-12-27 Gebrüder Sulzer Aktiengesellschaft Medical staple
US4711760A (en) 1986-02-27 1987-12-08 Westinghouse Electric Corp. Nuclear reactor incorporating locking device for threaded bolt connections
US4804290A (en) 1986-08-22 1989-02-14 Peter J. Balsells Latching and sealing device
US4978350A (en) 1986-10-13 1990-12-18 Jaquet Orthopedie S.A. Transcutaneous pin for fixation of a bone part or fragment
US4708377A (en) 1986-11-28 1987-11-24 Aeroquip Corporation Contractible coupling
US4714469A (en) 1987-02-26 1987-12-22 Pfizer Hospital Products Group, Inc. Spinal implant
FI78232C (en) 1987-06-15 1989-07-10 Trident Oy Implants, som ersaetter I tand or a part benvaevnaden with syntetiskt material.
DE3866614D1 (en) 1987-07-09 1992-01-16 Sulzer Ag Intervertebral prosthesis.
EP0298233B1 (en) 1987-07-09 1991-12-27 Gebrüder Sulzer Aktiengesellschaft Metallic spinal disc prosthesis
US5116374A (en) 1989-03-02 1992-05-26 Regen Corporation Prosthetic meniscus
US4812094A (en) 1987-09-24 1989-03-14 Maclean-Fogg Company Locking fastener assembly for threaded joint
US4829152A (en) 1987-11-16 1989-05-09 Rostoker, Inc. Method of resistance welding a porous body to a substrate
US5147404A (en) 1987-12-07 1992-09-15 Downey Ernest L Vertebra prosthesis
US4976576A (en) 1988-02-24 1990-12-11 The Boeing Company Captive self-locking mechanism
DE3809793A1 (en) 1988-03-23 1989-10-05 Link Waldemar Gmbh Co Surgical instrument set
US4950296A (en) 1988-04-07 1990-08-21 Mcintyre Jonathan L Bone grafting units
US5047058A (en) 1988-04-08 1991-09-10 Smith & Nephew Richards, Inc. System of inserts for the tibial component of a knee prosthesis
US4858603A (en) 1988-06-06 1989-08-22 Johnson & Johnson Orthopaedics, Inc. Bone pin
US5772661A (en) 1988-06-13 1998-06-30 Michelson; Gary Karlin Methods and instrumentation for the surgical correction of human thoracic and lumbar spinal disease from the antero-lateral aspect of the spine
US5484437A (en) 1988-06-13 1996-01-16 Michelson; Gary K. Apparatus and method of inserting spinal implants
US5860973A (en) 1995-02-27 1999-01-19 Michelson; Gary Karlin Translateral spinal implant
CA1333209C (en) 1988-06-28 1994-11-29 Gary Karlin Michelson Artificial spinal fusion implants
US4936851A (en) 1988-08-26 1990-06-26 Colin Electronics Co., Ltd. Analytic bone implant
US4961740B1 (en) 1988-10-17 1997-01-14 Surgical Dynamics Inc V-thread fusion cage and method of fusing a bone joint
US4872452A (en) 1989-01-09 1989-10-10 Minnesota Mining And Manufacturing Company Bone rasp
CA1318469C (en) 1989-02-15 1993-06-01 Acromed Corporation Artificial disc
US5020949A (en) 1989-03-08 1991-06-04 Davidson Eugene P Controlled-torque fastener
US5017069A (en) 1989-08-30 1991-05-21 Northrop Corporation Sleeve bolt
DE3933459A1 (en) 1989-10-06 1991-04-18 Karsten Dipl Ing Reumann Biomedical implant production equipment - uses computer tomographic image to generate implant profile for component mfr.
US5006120A (en) 1989-10-10 1991-04-09 Carter Peter R Distal radial fracture set and method for repairing distal radial fractures
DE8912648U1 (en) 1989-10-23 1990-11-22 Mecron Medizinische Produkte Gmbh, 1000 Berlin, De
US5235034A (en) 1989-11-06 1993-08-10 Phillips Petroleum Company Treatment of polyarylene sulfide/sulfone polymers with zinc compound and acidic solution
US5112354A (en) 1989-11-16 1992-05-12 Northwestern University Bone allograft material and method
GB8926319D0 (en) 1989-11-21 1990-01-10 Mcdonald John M Scaffolding
US5062850A (en) 1990-01-16 1991-11-05 University Of Florida Axially-fixed vertebral body prosthesis and method of fixation
FR2659226B1 (en) 1990-03-07 1992-05-29 Jbs Sa Prothese for intervertebral discs and instruments of implementation.
US5030220A (en) 1990-03-29 1991-07-09 Advanced Spine Fixation Systems Incorporated Spine fixation system
US5010783A (en) 1990-07-02 1991-04-30 Caterpillar Inc. Tappet retainer assembly
JPH06500711A (en) 1990-07-24 1994-01-27
DE69120177T2 (en) 1990-09-10 1996-10-10 Synthes Ag Membrane for bone regeneration
WO1992006005A1 (en) 1990-10-04 1992-04-16 Canadian Space Agency Interface for orbital replacement units
DE69111021T2 (en) 1990-10-31 1996-01-04 Gendler El A flexible membrane made from organic bone matrix for repairing and restoring bone.
US5348788A (en) 1991-01-30 1994-09-20 Interpore Orthopaedics, Inc. Mesh sheet with microscopic projections and holes
US5118235A (en) 1991-02-11 1992-06-02 Illinois Tool Works Inc. Washer with integral flap and fastening assembly combining fastener with such washer
DE59206078D1 (en) 1991-03-07 1996-05-30 Sulzer Medizinaltechnik Ag Nut for Implantatverschraubung
JP3007903B2 (en) 1991-03-29 2000-02-14 京セラ株式会社 Artificial disc
DE4215137A1 (en) 1991-06-04 1992-12-10 Man Ceramics Gmbh Implant for spinal
DE4121524C2 (en) 1991-06-28 1994-07-14 Deutsche Aerospace Airbus screw connection
US5306307A (en) 1991-07-22 1994-04-26 Calcitek, Inc. Spinal disk implant
FR2680461B1 (en) 1991-08-19 1993-11-26 Fabrication Mat Orthopedique Including osteosynthesis implant device for the spine and corresponding device for its implementation.
GB9120908D0 (en) 1991-10-02 1991-11-13 British Aerospace Thread locking assembly
US5235059A (en) * 1991-10-15 1993-08-10 Merck & Co., Inc. Tricyclic thienothiopyran carbonic anhydrase inhibitors
US5258031A (en) 1992-01-06 1993-11-02 Danek Medical Intervertebral disk arthroplasty
US5201736A (en) 1992-01-13 1993-04-13 Strauss Sorrell I Maxillofacial bone clamp
US5211664A (en) 1992-01-14 1993-05-18 Forschungsinstitut, Davos Laboratorium Fur Experimentelle Chirugie Shell structure for bone replacement
US5534031A (en) 1992-01-28 1996-07-09 Asahi Kogaku Kogyo Kabushiki Kaisha Prosthesis for spanning a space formed upon removal of an intervertebral disk
US5314476A (en) 1992-02-04 1994-05-24 Osteotech, Inc. Demineralized bone particles and flowable osteogenic composition containing same
US5366507A (en) 1992-03-06 1994-11-22 Sottosanti John S Method for use in bone tissue regeneration
US5282861A (en) 1992-03-11 1994-02-01 Ultramet Open cell tantalum structures for cancellous bone implants and cell and tissue receptors
DE4208115A1 (en) 1992-03-13 1993-09-16 Link Waldemar Gmbh Co intervertebral disc prosthesis
US5766251A (en) 1992-03-13 1998-06-16 Tomihisa Koshino Wedge-shaped spacer for correction of deformed extremities
GB2266246B (en) 1992-03-27 1996-08-07 Jesse Shirley & Son Limited Fracture fixation device
US5306309A (en) 1992-05-04 1994-04-26 Calcitek, Inc. Spinal disk implant and implantation kit
DE4220218C2 (en) 1992-06-20 1994-09-22 S & G Implants Gmbh Implant with an open-cell or open-cell metal structure
US5368593A (en) 1992-07-07 1994-11-29 Stark; John G. Devices and methods for attachment of spine fixation devices
FR2697996B1 (en) 1992-11-17 1995-01-06 Medinov Sa Modular assembly for a hip prosthesis.
DE4242889A1 (en) 1992-12-18 1994-06-23 Merck Patent Gmbh Hohlendoprothesen with bone growth-promoting filling
CA2103200A1 (en) 1992-12-28 1994-06-29 Robert S. Howland Cervical spine rod fixation system
US5238342A (en) 1993-01-06 1993-08-24 Monogram Aerospace Industries, Inc. Blind fastener with mechanical thread lock
FR2700947B1 (en) 1993-02-03 1995-03-17 Daniel Noyer femoral implant prosthesis for hip dysplasia.
DE69428143D1 (en) 1993-02-09 2001-10-11 Acromed Corp disc
US6066175A (en) 1993-02-16 2000-05-23 Henderson; Fraser C. Fusion stabilization chamber
FR2703580B1 (en) 1993-03-03 1997-10-17 Gilles Robert Cage cervical interbody.
US5601554A (en) 1993-03-04 1997-02-11 Advanced Spine Fixation Systems, Inc. Branch connector for spinal fixation systems
US5487744A (en) 1993-04-08 1996-01-30 Advanced Spine Fixation Systems, Inc. Closed connector for spinal fixation systems
US5380323A (en) 1993-06-16 1995-01-10 Advanced Spine Fixation Systems, Inc. Clamps for spinal fixation systems
US5534027A (en) 1993-06-21 1996-07-09 Zimmer, Inc. Method for providing a barrier to the advancement of wear debris in an orthopaedic implant assembly
DE4423826B4 (en) 1993-07-07 2007-01-04 Pentax Corp. Ceramic prosthesis
US5423817A (en) 1993-07-29 1995-06-13 Lin; Chih-I Intervertebral fusing device
FR2708461B1 (en) 1993-08-06 1995-09-29 Advanced Technical Fabrication intersomatic implant for spine.
DE4328062A1 (en) 1993-08-20 1995-02-23 Heinrich Ulrich Implant for the replacement of vertebral bodies and / or to the stabilization and fixation of the spine
DE4328690B4 (en) 1993-08-26 2006-08-17 SDGI Holdings, Inc., Wilmington An intervertebral implant for Wirbelkörperverblockung and implantation instrument for positioning of the intervertebral implant
US5458641A (en) 1993-09-08 1995-10-17 Ramirez Jimenez; Juan J. Vertebral body prosthesis
US5425772A (en) 1993-09-20 1995-06-20 Brantigan; John W. Prosthetic implant for intervertebral spinal fusion
US5443514A (en) 1993-10-01 1995-08-22 Acromed Corporation Method for using spinal implants
US5545842A (en) 1993-10-26 1996-08-13 Bal Seal Engineering Company, Inc. Radially mounted spring to connect, lock and unlock, and for snap-on fastening, and for mechanical, electromagnetic shielding, electrical conductivity, and thermal dissipation with environmental sealing
US5411348A (en) 1993-10-26 1995-05-02 Bal Seal Engineering Company, Inc. Spring mechanism to connect, lock and unlock, members
US5514180A (en) 1994-01-14 1996-05-07 Heggeness; Michael H. Prosthetic intervertebral devices
FR2715293B1 (en) 1994-01-26 1996-03-22 Biomat Vertebral intersomatic cage.
US5443515A (en) 1994-01-26 1995-08-22 Implex Corporation Vertebral body prosthetic implant with slidably positionable stabilizing member
DE4403509A1 (en) 1994-02-04 1995-08-10 Draenert Klaus Material and process for its preparation
DE59408730D1 (en) 1994-02-07 1999-10-14 Sulzer Orthopaedie Ag Outer shell to an at least two shelled joint socket of a hip prosthesis and hip prosthesis with such an outer shell
US5431658A (en) 1994-02-14 1995-07-11 Moskovich; Ronald Facilitator for vertebrae grafts and prostheses
DE4409392A1 (en) 1994-03-18 1995-09-21 Biedermann Motech Gmbh Height-adjustable vertebral body
DK1197181T3 (en) 1994-03-28 2005-03-14 Michelson Gary K A device for spinal fixation
US5571189A (en) 1994-05-20 1996-11-05 Kuslich; Stephen D. Expandable fabric implant for stabilizing the spinal motion segment
US5906827A (en) 1994-06-03 1999-05-25 Creative Biomolecules, Inc. Matrix for the manufacture of autogenous replacement body parts
EP0765139A2 (en) 1994-06-17 1997-04-02 OLERUD, Sven A bone screw for osteosynthesis
US5478342A (en) 1994-06-30 1995-12-26 Spinetech, Inc. Reversible bone screw lock
DE4423257C2 (en) 1994-07-02 2001-07-12 Ulrich Heinrich Implant for insertion between vertebral bodies of the spinal column as a place holder
US5980522A (en) 1994-07-22 1999-11-09 Koros; Tibor Expandable spinal implants
ES2139792T3 (en) 1994-08-09 2000-02-16 Salice Arturo Spa Fastener.
WO1996005778A1 (en) 1994-08-23 1996-02-29 Spinetech, Inc. Cervical spine stabilization system
ES2171193T3 (en) 1994-09-15 2002-09-01 Surgical Dynamics Inc Box conically shaped anterior fusion.
US5681311A (en) 1994-09-15 1997-10-28 Smith & Nephew, Inc. Osteosynthesis apparatus
US5570983A (en) 1994-09-27 1996-11-05 Hollander; Andrew A. Reduced-friction screw
US5674296A (en) 1994-11-14 1997-10-07 Spinal Dynamics Corporation Human spinal disc prosthesis
FR2727003B1 (en) 1994-11-18 1997-04-18 Euros Sa A stabilization of the anterior lumbosacral spine
DE69534042T2 (en) 1994-12-09 2006-04-13 SDGI Holdings, Inc., Wilmington Adjustable vertebral body replacement
US5776197A (en) 1994-12-09 1998-07-07 Sdgi Holdings, Inc. Adjustable vertebral body replacement
US5766252A (en) 1995-01-24 1998-06-16 Osteonics Corp. Interbody spinal prosthetic implant and method
US5683216A (en) 1995-02-02 1997-11-04 General Electric Company Spring latching mechanisms for preventing relative movement of assembled components
US5550172A (en) 1995-02-07 1996-08-27 Ethicon, Inc. Utilization of biocompatible adhesive/sealant materials for securing surgical devices
DE19504867C1 (en) 1995-02-14 1996-02-29 Harms Juergen Position retainer for spine
US5976141A (en) 1995-02-23 1999-11-02 Synthes (U.S.A.) Threaded insert for bone plate screw hole
US5620448A (en) 1995-03-24 1997-04-15 Arthrex, Inc. Bone plate system for opening wedge proximal tibial osteotomy
US5782919A (en) 1995-03-27 1998-07-21 Sdgi Holdings, Inc. Interbody fusion device and method for restoration of normal spinal anatomy
JP3501542B2 (en) 1995-04-07 2004-03-02 富久 腰野 Medical hard tissue replacement members and prosthesis
US6558387B2 (en) 2001-01-30 2003-05-06 Fastemetix, Llc Porous interbody fusion device having integrated polyaxial locking interference screws
US5607428A (en) 1995-05-01 1997-03-04 Lin; Kwan C. Orthopedic fixation device having a double-threaded screw
US5702449A (en) 1995-06-07 1997-12-30 Danek Medical, Inc. Reinforced porous spinal implants
US5578034A (en) 1995-06-07 1996-11-26 Danek Medical, Inc. Apparatus for preventing screw backout in a bone plate fixation system
CN1171564C (en) 1995-06-07 2004-10-20 加里・K・米切尔森 Translateral spinal implant
EP0749733B1 (en) 1995-06-21 2002-05-29 Sulzer Orthopädie AG Tibialplatform for a knee-joint prosthesis and knee-joint prosthesis with such a tibialplatform
US5597278A (en) 1995-07-24 1997-01-28 Maclean-Fogg Company Locking fastener assembly for threaded joint
US5902338A (en) 1995-09-15 1999-05-11 Crosscart, Inc. Anterior cruciate ligament heterograft
US5944755A (en) 1995-09-15 1999-08-31 Crosscart, Inc. Articular cartilage xenografts
US5782915A (en) 1995-09-15 1998-07-21 Stone; Kevin R. Articular cartilage heterografts
US5683394A (en) 1995-09-29 1997-11-04 Advanced Spine Fixation Systems, Inc. Fusion mass constrainer
US5989289A (en) 1995-10-16 1999-11-23 Sdgi Holdings, Inc. Bone grafts
DE19541114A1 (en) 1995-10-26 1997-04-30 Artos Med Produkte Intervertebral implant
US5778804A (en) 1995-11-17 1998-07-14 Read; Donald E. Fastening apparatus
FR2742653B1 (en) 1995-12-21 1998-02-27 Colorado Cage vertebral interbody
US5725531A (en) 1995-12-27 1998-03-10 Shapiro; Jules S. Reaming device
US5814084A (en) 1996-01-16 1998-09-29 University Of Florida Tissue Bank, Inc. Diaphysial cortical dowel
US5766253A (en) 1996-01-16 1998-06-16 Surgical Dynamics, Inc. Spinal fusion device
EP0880345B1 (en) 1996-01-17 2006-04-05 Osteotech, Inc., Process for producing flexible sheets from demineralized, elongate, bone particles
JPH09280219A (en) 1996-02-14 1997-10-28 Sekisui Chem Co Ltd Easy release joint
US5824078A (en) 1996-03-11 1998-10-20 The Board Of Trustees Of The University Of Arkansas Composite allograft, press, and methods
FR2747034B1 (en) * 1996-04-03 1998-06-19 Scient X contention system and intersomatic fusion
US5776194A (en) 1996-04-25 1998-07-07 Nuvana Medical Innovations, Llc Intermedullary rod apparatus and methods of repairing proximal humerus fractures
US5713900A (en) 1996-05-31 1998-02-03 Acromed Corporation Apparatus for retaining bone portions in a desired spatial relationship
US5800433A (en) 1996-05-31 1998-09-01 Acromed Corporation Spinal column retaining apparatus
US5755796A (en) 1996-06-06 1998-05-26 Ibo; Ivo Prosthesis of the cervical intervertebralis disk
US5702455A (en) 1996-07-03 1997-12-30 Saggar; Rahul Expandable prosthesis for spinal fusion
US5964807A (en) 1996-08-08 1999-10-12 Trustees Of The University Of Pennsylvania Compositions and methods for intervertebral disc reformation
FR2753368B1 (en) 1996-09-13 1999-01-08 Chauvin Jean Luc Cage expansive osteosynthesis
DE19638790A1 (en) * 1996-09-21 1998-03-26 Mann & Hummel Filter air filter
EP1364617B1 (en) 1996-10-22 2005-08-10 Howmedica Osteonics Corp. Surgical drill and retractor
US5968098A (en) 1996-10-22 1999-10-19 Surgical Dynamics, Inc. Apparatus for fusing adjacent bone structures
DE69728424T2 (en) 1996-10-23 2005-02-17 SDGI Holdings, Inc., Wilmington Spacer for invertebrates
US5920312A (en) 1996-10-31 1999-07-06 Ncr Corporation System and method for building testing and integrating a graphical dynakey user interface
US5836948A (en) 1997-01-02 1998-11-17 Saint Francis Medical Technologies, Llc Spine distraction implant and method
US5749916A (en) 1997-01-21 1998-05-12 Spinal Innovations Fusion implant
DE29701099U1 (en) 1997-01-23 1997-03-06 Aesculap Ag Pin-shaped retaining element for an orthopedic retaining system
US5931838A (en) 1997-01-28 1999-08-03 Vito; Raymond P. Fixation assembly for orthopedic applications
US6139550A (en) 1997-02-11 2000-10-31 Michelson; Gary K. Skeletal plating system
CA2445303C (en) 1997-02-11 2006-01-10 Gary Karlin Michelson Single-lock anterior cervical plating system
US7141665B1 (en) 1998-04-29 2006-11-28 The Scripps Research Institute Enzymatic DNA molecules
US6017345A (en) 1997-05-09 2000-01-25 Spinal Innovations, L.L.C. Spinal fixation plate
US5972368A (en) 1997-06-11 1999-10-26 Sdgi Holdings, Inc. Bone graft composites and spacers
US5910315A (en) 1997-07-18 1999-06-08 Stevenson; Sharon Allograft tissue material for filling spinal fusion cages or related surgical spaces
US5904719A (en) 1997-07-24 1999-05-18 Techsys Medical, Llc Interbody fusion device having partial circular section cross-sectional segments
US5954722A (en) 1997-07-29 1999-09-21 Depuy Acromed, Inc. Polyaxial locking plate
US6146421A (en) 1997-08-04 2000-11-14 Gordon, Maya, Roberts And Thomas, Number 1, Llc Multiple axis intervertebral prosthesis
WO1999009914A1 (en) 1997-08-27 1999-03-04 University Of Florida Tissue Bank, Inc. Cortical bone cervical smith-robinson fusion implant
WO1999009903A1 (en) 1997-08-27 1999-03-04 Synthes Ag Chur Locking ring with bayonet for plate osteosynthesis
US6086595A (en) 1997-08-29 2000-07-11 Sulzer Spine-Tech Inc. Apparatus and method for spinal stabilization
US6511509B1 (en) 1997-10-20 2003-01-28 Lifenet Textured bone allograft, method of making and using same
EP1027005A1 (en) 1997-10-24 2000-08-16 Robert S. Bray, Jr. Bone plate and bone screw guide mechanism
US6090998A (en) 1997-10-27 2000-07-18 University Of Florida Segmentally demineralized bone implant
KR20010032576A (en) 1997-11-29 2001-04-25 안토니 알. 피어스 Surgical implant and surgical fixing screw
US20010001129A1 (en) * 1997-12-10 2001-05-10 Mckay William F. Osteogenic fusion device
US6146420A (en) 1997-12-10 2000-11-14 Sdgi Holdings, Inc. Osteogenic fusion device
US6086613A (en) 1997-12-23 2000-07-11 Depuy Acromed, Inc. Spacer assembly for use in spinal surgeries
US5899939A (en) 1998-01-21 1999-05-04 Osteotech, Inc. Bone-derived implant for load-supporting applications
US6086614A (en) 1998-01-23 2000-07-11 Sulzer Orthopedics Inc. Orthopedic prosthesis having anti-backout screw
US6482233B1 (en) 1998-01-29 2002-11-19 Synthes(U.S.A.) Prosthetic interbody spacer
US6143033A (en) 1998-01-30 2000-11-07 Synthes (Usa) Allogenic intervertebral implant
US6123731A (en) 1998-02-06 2000-09-26 Osteotech, Inc. Osteoimplant and method for its manufacture
US5951558A (en) 1998-04-22 1999-09-14 Fiz; Daniel Bone fixation device
US6008433A (en) 1998-04-23 1999-12-28 Stone; Kevin R. Osteotomy wedge device, kit and methods for realignment of a varus angulated knee
FR2778088B1 (en) 1998-04-30 2000-09-08 Materiel Orthopedique En Abreg anterior implant in particular for the cervical spine
US6258089B1 (en) 1998-05-19 2001-07-10 Alphatec Manufacturing, Inc. Anterior cervical plate and fixation system
US6001099A (en) 1998-06-08 1999-12-14 Huebner; Randall J. Bone plate with varying rigidity
US6682561B2 (en) * 1998-06-18 2004-01-27 Pioneer Laboratories, Inc. Spinal fixation system
GB9813566D0 (en) 1998-06-23 1998-08-19 Biomet Merck Ltd Vertebral body replacement
EP0968692A1 (en) 1998-06-29 2000-01-05 Christos Kalaitzis Plate-cylinder vertebral prosthesis system
US6086593A (en) 1998-06-30 2000-07-11 Bonutti; Peter M. Method and apparatus for use in operating on a bone
US5904683A (en) 1998-07-10 1999-05-18 Sulzer Spine-Tech Inc. Anterior cervical vertebral stabilizing device
CA2338379A1 (en) 1998-07-22 2000-02-03 Spinal Dynamics Corporation Threaded cylindrical multidiscoid single or multiple array disc prosthesis
DE29813139U1 (en) 1998-07-23 1998-12-03 Howmedica Gmbh Vertebral reconstruction system
EP1100417B1 (en) 1998-08-03 2004-04-07 SYNTHES AG Chur Intervertebral allograft spacer
WO2000007528A1 (en) 1998-08-06 2000-02-17 Sdgi Holdings, Inc. Composited intervertebral bone spacers
US6241731B1 (en) 1998-08-11 2001-06-05 Daniel Fiz Plate and screw assembly for fixing bones
FR2784570B1 (en) 1998-10-19 2001-02-16 Scient X INTERVERTEBRAL connecting device equipped with anti-extraction means for the anchoring screws
US6113637A (en) 1998-10-22 2000-09-05 Sofamor Danek Holdings, Inc. Artificial intervertebral joint permitting translational and rotational motion
US6193757B1 (en) 1998-10-29 2001-02-27 Sdgi Holdings, Inc. Expandable intervertebral spacers
WO2001078798A1 (en) * 2000-02-10 2001-10-25 Regeneration Technologies, Inc. Assembled implant
US20010031254A1 (en) 1998-11-13 2001-10-18 Bianchi John R. Assembled implant
DE19858889B4 (en) 1998-12-19 2008-08-07 Wolter, Dietmar, Prof. Dr.Med. Fixation system for bones
US6206923B1 (en) * 1999-01-08 2001-03-27 Sdgi Holdings, Inc. Flexible implant using partially demineralized bone
EP1139930B1 (en) 1999-01-11 2005-09-14 SDGI Holdings, Inc. Intervertebral spacers with side wall accessible interior cavity
US6245108B1 (en) * 1999-02-25 2001-06-12 Spineco Spinal fusion implant
US6113638A (en) 1999-02-26 2000-09-05 Williams; Lytton A. Method and apparatus for intervertebral implant anchorage
US6056749A (en) 1999-03-15 2000-05-02 Spineology, Inc. Method and device for fixing and correcting spondylolisthesis anteriorly
US6156070A (en) 1999-03-26 2000-12-05 Howmedica Osteonics Corp. Allograft prosthetic joints and method
US6143030A (en) 1999-03-26 2000-11-07 Bristol-Myers Squibb Co. Impaction allograft form and method of orthopaedic surgery using same
US6602291B1 (en) 1999-04-05 2003-08-05 Raymedica, Inc. Prosthetic spinal disc nucleus having a shape change characteristic
US6387130B1 (en) 1999-04-16 2002-05-14 Nuvasive, Inc. Segmented linked intervertebral implant systems
EP1198208B1 (en) 1999-05-05 2013-07-10 Warsaw Orthopedic, Inc. Nested interbody spinal fusion implants
EP1194086A4 (en) 1999-06-08 2003-03-19 Osteotech Inc Keyed intervertebral dowel
US6770096B2 (en) 1999-07-01 2004-08-03 Spinevision S.A. Interbody spinal stabilization cage and spinal stabilization method
US6261291B1 (en) 1999-07-08 2001-07-17 David J. Talaber Orthopedic implant assembly
FR2795945B1 (en) 1999-07-09 2001-10-26 Scient X Intersomatic implant anatomical and gripper for such an implant
DE29913200U1 (en) 1999-07-28 1999-09-23 Tutogen Medical Gmbh Implant made of bone material
US6080158A (en) 1999-08-23 2000-06-27 Lin; Chih-I Intervertebral fusion device
US6231610B1 (en) * 1999-08-25 2001-05-15 Allegiance Corporation Anterior cervical column support device
WO2001017465A1 (en) 1999-09-03 2001-03-15 Cook Daniel J Temporary spine fixation device and method
CA2408327C (en) 1999-09-13 2006-12-19 Synthes (U.S.A.) Bone plate system
US6264695B1 (en) * 1999-09-30 2001-07-24 Replication Medical, Inc. Spinal nucleus implant
US6224602B1 (en) 1999-10-11 2001-05-01 Interpore Cross International Bone stabilization plate with a secured-locking mechanism for cervical fixation
DE19951760B4 (en) 1999-10-27 2005-06-09 Sepitec Foundation Implant for osteosynthesis
US6461359B1 (en) 1999-11-10 2002-10-08 Clifford Tribus Spine stabilization device
US6432106B1 (en) 1999-11-24 2002-08-13 Depuy Acromed, Inc. Anterior lumbar interbody fusion cage with locking plate
US6592624B1 (en) 1999-11-24 2003-07-15 Depuy Acromed, Inc. Prosthetic implant element
US6331179B1 (en) 2000-01-06 2001-12-18 Spinal Concepts, Inc. System and method for stabilizing the human spine with a bone plate
WO2001056497B1 (en) 2000-02-04 2002-03-07 Gary K Michelson Expandable interbody spinal fusion implant
EP1645248B8 (en) 2000-02-04 2010-06-16 Warsaw Orthopedic, Inc. Expandable interbody spinal fusion implant having pivotally attached blocker
FR2805457B1 (en) 2000-02-24 2002-10-11 Stryker Spine Sa Intervertebral implant body and a support surface
US6872915B2 (en) 2000-03-01 2005-03-29 Kabushiki Kaisha Yaskawa Denki High speed carbon dioxide gas welding method
EP1263354A1 (en) 2000-03-09 2002-12-11 Osteotech, Inc., Anterior lumbar spacer
US6767369B2 (en) 2000-03-22 2004-07-27 Synthes (Usa) Plugs for filling bony defects
US6235033B1 (en) 2000-04-19 2001-05-22 Synthes (Usa) Bone fixation assembly
US6500205B1 (en) 2000-04-19 2002-12-31 Gary K. Michelson Expandable threaded arcuate interbody spinal fusion implant with cylindrical configuration during insertion
EP1274356A1 (en) 2000-04-20 2003-01-15 SYNTHES AG Chur Device for fixing implants on or in a bone
FR2808995B1 (en) 2000-05-18 2003-02-21 Aesculap Sa The intersomatic cage has unified grafts
US6923756B2 (en) 2000-06-05 2005-08-02 Boris Sudakov Multifunctional medical tool
WO2001095837A1 (en) 2000-06-13 2001-12-20 Michelson Gary K Manufactured major long bone ring implant shaped to conform to a prepared intervertebral implantation space
US20020111680A1 (en) * 2000-06-13 2002-08-15 Michelson Gary K. Ratcheted bone dowel
US7018416B2 (en) 2000-07-06 2006-03-28 Zimmer Spine, Inc. Bone implants and methods
US6638310B2 (en) 2000-07-26 2003-10-28 Osteotech, Inc. Intervertebral spacer and implant insertion instrumentation
US6447546B1 (en) 2000-08-11 2002-09-10 Dale G. Bramlet Apparatus and method for fusing opposing spinal vertebrae
US6629998B1 (en) 2000-08-23 2003-10-07 Chih-I Lin Intervertebral retrieval device
US6443987B1 (en) 2000-09-15 2002-09-03 Donald W. Bryan Spinal vertebral implant
US20060142765A9 (en) 2001-10-15 2006-06-29 Dixon Robert A Vertebral implant for bone fixation or interbody use
US6605090B1 (en) 2000-10-25 2003-08-12 Sdgi Holdings, Inc. Non-metallic implant devices and intra-operative methods for assembly and fixation
EP1330215A2 (en) * 2000-11-03 2003-07-30 Osteotech, Inc. Spinal intervertebral implant and method of making
US6656181B2 (en) 2000-11-22 2003-12-02 Robert A Dixon Method and device utilizing tapered screw shanks for spinal stabilization
US6413259B1 (en) 2000-12-14 2002-07-02 Blackstone Medical, Inc Bone plate assembly including a screw retaining member
US6468311B2 (en) 2001-01-22 2002-10-22 Sdgi Holdings, Inc. Modular interbody fusion implant
US6972019B2 (en) 2001-01-23 2005-12-06 Michelson Gary K Interbody spinal implant with trailing end adapted to receive bone screws
EP1355593B1 (en) 2001-01-30 2006-05-24 Synthes AG Chur Bone implant, in particular, an inter-vertebral implant
US6576017B2 (en) 2001-02-06 2003-06-10 Sdgi Holdings, Inc. Spinal implant with attached ligament and methods
US6562073B2 (en) 2001-02-06 2003-05-13 Sdgi Holding, Inc. Spinal bone implant
DE10116412C1 (en) 2001-04-02 2003-01-16 Ulrich Gmbh & Co Kg Implant for insertion between vertebral bodies of the spine
FR2823096B1 (en) * 2001-04-06 2004-03-19 Materiel Orthopedique En Abreg Bone plate apparatus of vertebrae L5 and S1 osteosynthesis device including such a plate, and the tool for placing such a plate
US6558424B2 (en) 2001-06-28 2003-05-06 Depuy Acromed Modular anatomic fusion device
US7833245B2 (en) 2001-07-12 2010-11-16 Osteotech, Inc. Intervertebral implant with movement resistant structure
FR2827156B1 (en) 2001-07-13 2003-11-14 Ldr Medical A spinal cage modular fixture with
EP1287795B1 (en) 2001-08-24 2008-06-18 Zimmer GmbH Artificial spinal disc
US6569201B2 (en) * 2001-09-28 2003-05-27 Depuy Acromed, Inc. Hybrid composite interbody fusion device
US6648917B2 (en) 2001-10-17 2003-11-18 Medicinelodge, Inc. Adjustable bone fusion implant and method
US7025787B2 (en) 2001-11-26 2006-04-11 Sdgi Holdings, Inc. Implantable joint prosthesis and associated instrumentation
US6736850B2 (en) 2001-12-28 2004-05-18 Spinal Concepts, Inc. Vertebral pseudo arthrosis device and method
US7077864B2 (en) 2002-02-12 2006-07-18 Cross Medical Products, Inc. Vertebral interbody cage with translatable locking screw
EP1534194A2 (en) 2002-06-26 2005-06-01 Nuvasive, Inc. Total disc replacement system and related methods
JP4088495B2 (en) 2002-08-20 2008-05-21 昭和医科工業株式会社 Intervertebral cage
RU2229271C1 (en) 2002-09-09 2004-05-27 Государственное федеральное учреждение науки Уральский научно-исследовательский институт травматологии и ортопедии им. В.Д. Чаклина Method and device for treating the cases of retrospondylolisthesis
US20040092929A1 (en) 2002-09-27 2004-05-13 Zindrick Michael R. Spinal plate with means to secure a graft
US6899735B2 (en) 2002-10-02 2005-05-31 Sdgi Holdings, Inc. Modular intervertebral prosthesis system
US7214243B2 (en) 2002-10-21 2007-05-08 3Hbfm, Llc Intervertebral disk prosthesis
US7232463B2 (en) 2002-10-23 2007-06-19 U.S. Spinal Technologies, Llc Intervertebral cage designs
US7497859B2 (en) 2002-10-29 2009-03-03 Kyphon Sarl Tools for implanting an artificial vertebral disk
US20040133278A1 (en) 2002-10-31 2004-07-08 Marino James F. Spinal disc implant
US6723126B1 (en) 2002-11-01 2004-04-20 Sdgi Holdings, Inc. Laterally expandable cage
US6761739B2 (en) * 2002-11-25 2004-07-13 Musculoskeletal Transplant Foundation Cortical and cancellous allograft spacer
US6974479B2 (en) 2002-12-10 2005-12-13 Sdgi Holdings, Inc. System and method for blocking and/or retaining a prosthetic spinal implant
US20040210310A1 (en) 2002-12-10 2004-10-21 Trieu Hai H. Implant system and method for intervertebral disc augmentation
CN100457062C (en) 2002-12-17 2009-02-04 斯恩蒂斯有限公司 Intervertebral implant
RU2244527C2 (en) 2003-01-21 2005-01-20 Научно-исследовательский центр Татарстана "Восстановительная травматология и ортопедия" Device for fixing the vertebral column and device for setting it
US20040176853A1 (en) 2003-03-05 2004-09-09 Sennett Andrew R. Apparatus and method for spinal fusion using posteriorly implanted devices
US6908484B2 (en) 2003-03-06 2005-06-21 Spinecore, Inc. Cervical disc replacement
US7060097B2 (en) 2003-03-31 2006-06-13 Depuy Spine, Inc. Method and apparatus for implant stability
US7112222B2 (en) 2003-03-31 2006-09-26 Depuy Spine, Inc. Anterior lumbar interbody fusion cage with locking plate
CA2519925A1 (en) 2003-04-07 2004-10-21 Cervitech, Inc. Prosthetic joint of cervical intervertebral for a cervical spine
US8100976B2 (en) 2003-04-21 2012-01-24 Rsb Spine Llc Implant subsidence control
US9278009B2 (en) 2003-04-21 2016-03-08 Rsb Spine Llc Spine implants
KR100973034B1 (en) 2003-07-22 2010-07-30 신세스 게엠바하 Intervertebral implant comprising dome-shaped joint surfaces
US7226482B2 (en) 2003-09-02 2007-06-05 Synthes (U.S.A.) Multipiece allograft implant
US7794465B2 (en) 2003-09-10 2010-09-14 Warsaw Orthopedic, Inc. Artificial spinal discs and associated implantation instruments and methods
US7766914B2 (en) 2003-09-10 2010-08-03 Warsaw Orthopedic, Inc. Adjustable drill guide
US20050065605A1 (en) 2003-09-18 2005-03-24 Jackson Roger P. Threaded center line cage with funnel shaped profile
US20050065607A1 (en) 2003-09-24 2005-03-24 Gross Jeffrey M. Assembled fusion implant
GB0325421D0 (en) 2003-10-30 2003-12-03 Gill Steven S An intervertebral prosthesis
US7837732B2 (en) 2003-11-20 2010-11-23 Warsaw Orthopedic, Inc. Intervertebral body fusion cage with keels and implantation methods
US20050203515A1 (en) 2003-12-30 2005-09-15 Thomas Doherty Bone anchor assemblies
US7621938B2 (en) 2004-01-15 2009-11-24 Warsaw Orthopedic, Inc. Spinal implant construct and method for implantation
WO2005097004A3 (en) 2004-03-26 2007-04-26 Synthes Usa Allograft implant
US8172904B2 (en) 2004-06-30 2012-05-08 Synergy Disc Replacement, Inc. Artificial spinal disc
DE602005036752T8 (en) 2004-06-30 2013-04-25 Synergy Disc Replacement Inc. Artificial disc
US20060020342A1 (en) 2004-07-21 2006-01-26 Ferree Bret A Facet-preserving artificial disc replacements
US7625380B2 (en) 2004-07-21 2009-12-01 Warsaw Orthopedic, Inc. Dual distractor inserter
US20060085076A1 (en) 2004-10-15 2006-04-20 Manoj Krishna Posterior spinal arthroplasty-development of a new posteriorly inserted artificial disc and an artificial facet joint
US20060129240A1 (en) 2004-12-10 2006-06-15 Joe Lessar Implants based on engineered composite materials having enhanced imaging and wear resistance
FR2879436B1 (en) 2004-12-22 2007-03-09 Ldr Medical Prothese of intervertebral disc
DE202004020209U1 (en) 2004-12-30 2006-05-04 Mathys Medizinaltechnik Ag Aiming device for surgical drills and introduction of bone fixing means has aiming body comprising positioning device arranged at front surfaces which are insertable in hole on an implant
US7972363B2 (en) 2005-04-12 2011-07-05 Moskowitz Ahmnon D Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs and posterior cervical and lumbar interarticulating joint stapling guns and devices for spinal fusion
US7704279B2 (en) 2005-04-12 2010-04-27 Moskowitz Mosheh T Bi-directional fixating transvertebral body screws, zero-profile horizontal intervertebral miniplates, expansile intervertebral body fusion devices, and posterior motion-calibrating interarticulating joint stapling device for spinal fusion
US7846188B2 (en) 2005-04-12 2010-12-07 Moskowitz Nathan C Bi-directional fixating transvertebral body screws, zero-profile horizontal intervertebral miniplates, total intervertebral body fusion devices, and posterior motion-calibrating interarticulating joint stapling device for spinal fusion
US7942903B2 (en) 2005-04-12 2011-05-17 Moskowitz Ahmnon D Bi-directional fixating transvertebral body screws and posterior cervical and lumbar interarticulating joint calibrated stapling devices for spinal fusion
US7955358B2 (en) 2005-09-19 2011-06-07 Albert Todd J Bone screw apparatus, system and method
US7699880B2 (en) 2005-10-24 2010-04-20 Depuy Products, Inc. Bone fixation system and bone screws having anti-back out feature
US20070123987A1 (en) 2005-11-02 2007-05-31 Bernstein Avi J Curvilinear cervical interbody device
FR2893838B1 (en) 2005-11-30 2008-08-08 Ldr Medical Soc Par Actions Si intervertebral disk prosthesis and instrumentation for inserting the prosthesis between the vertebrae
US7594932B2 (en) 2005-12-29 2009-09-29 International Spinal Innovations, Llc Apparatus for anterior intervertebral spinal fixation and fusion
RU2307625C1 (en) 2006-01-10 2007-10-10 Государственное образовательное учреждение дополнительного профессионального образования "Новокузнецкий государственный институт усовершенствования врачей Федерального агентства по здравоохранению и социальному развитию" Arrangement for spondylosyndesis
US7815680B2 (en) 2006-01-13 2010-10-19 Nabil L. Muhanna Flexible vertebral implant
EP1988855A2 (en) 2006-02-27 2008-11-12 Synthes GmbH Intervertebral implant with fixation geometry
US20070225806A1 (en) 2006-03-24 2007-09-27 Sdgi Holdings, Inc. Arthroplasty device
US20070270961A1 (en) 2006-04-25 2007-11-22 Sdgi Holdings, Inc. Spinal implant with deployable and retractable barbs
CA2658876C (en) 2006-07-24 2015-03-17 Spine Solutions, Inc. Intervertebral implant with keel
US8062303B2 (en) 2006-08-16 2011-11-22 K2M, Inc. Apparatus and methods for inserting an implant
US8128700B2 (en) 2006-09-13 2012-03-06 Synthes Usa, Llc Allograft intervertebral implant and method of manufacturing the same
US9381098B2 (en) 2006-09-28 2016-07-05 Spinal Kinetics, Inc. Tool systems for implanting prosthetic intervertebral discs
US7850731B2 (en) 2006-10-04 2010-12-14 Seaspine, Inc. Articulating spinal implant
US7997039B2 (en) 2006-12-29 2011-08-16 Boral Stone Products, LLC Veneer panel
US8465546B2 (en) 2007-02-16 2013-06-18 Ldr Medical Intervertebral disc prosthesis insertion assemblies
US20080249569A1 (en) 2007-04-03 2008-10-09 Warsaw Orthopedic, Inc. Implant Face Plates
US8268000B2 (en) 2007-04-03 2012-09-18 Warsaw Orthopedic, Inc. Composite interbody spacer
US8425607B2 (en) 2007-04-03 2013-04-23 Warsaw Orthopedic, Inc. Anchor member locking features
US8211148B2 (en) 2007-04-24 2012-07-03 Warsaw Orthopedic Prostheses for locking an artificial disc in an intervertebral disc space
US8273127B2 (en) 2007-06-06 2012-09-25 Spinesmith Partners, L.P. Interbody fusion device and associated methods
US8540774B2 (en) 2007-11-16 2013-09-24 DePuy Synthes Products, LLC Low profile intervertebral implant
US8377132B2 (en) 2008-01-16 2013-02-19 Aesculap Implant Systems, Llc Standalone dynamic interbody
US20090210062A1 (en) 2008-02-20 2009-08-20 John Thalgott Orthopaedic Implants and Prostheses
US8425514B2 (en) 2008-06-25 2013-04-23 Westmark Medical, Llc. Spinal fixation device
US8328872B2 (en) 2008-09-02 2012-12-11 Globus Medical, Inc. Intervertebral fusion implant
WO2010054181A1 (en) 2008-11-07 2010-05-14 Synthes Usa, Llc Vertebral interbody spacer and coupled plate assembly
US8545567B1 (en) 2008-11-14 2013-10-01 David Krueger Spinal fusion device
US8308804B2 (en) 2008-11-14 2012-11-13 David Krueger Spinal fusion device
EP2654626B1 (en) 2010-12-21 2016-02-24 Synthes GmbH Intervertebral implants and systems
US9241809B2 (en) 2010-12-21 2016-01-26 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
US9770340B2 (en) 2011-09-16 2017-09-26 Globus Medical, Inc. Multi-piece intervertebral implants
US20140336770A1 (en) 2011-09-16 2014-11-13 Globus Medical, Inc Low Profile Plate
US8961606B2 (en) 2011-09-16 2015-02-24 Globus Medical, Inc. Multi-piece intervertebral implants
US9398960B2 (en) 2011-09-16 2016-07-26 Globus Medical, Inc. Multi-piece intervertebral implants
US9204975B2 (en) 2011-09-16 2015-12-08 Globus Medical, Inc. Multi-piece intervertebral implants
US9237957B2 (en) 2011-09-16 2016-01-19 Globus Medical, Inc. Low profile plate
US9848994B2 (en) 2011-09-16 2017-12-26 Globus Medical, Inc. Low profile plate
US9149365B2 (en) 2013-03-05 2015-10-06 Globus Medical, Inc. Low profile plate

Patent Citations (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4135506A (en) * 1976-03-16 1979-01-23 Ulrich Max B Method of and device for pinning a fractured vertebra
US4512038A (en) * 1979-04-27 1985-04-23 University Of Medicine And Dentistry Of New Jersey Bio-absorbable composite tissue scaffold
US4503848A (en) * 1981-04-08 1985-03-12 Aesculap-Werke Aktiengesellschaft Osteosynthesis plate
US4501269A (en) * 1981-12-11 1985-02-26 Washington State University Research Foundation, Inc. Process for fusing bone joints
US4717115A (en) * 1986-10-14 1988-01-05 The United States Of America As Represented By The Secretary Of The Army Adjustable mold for fabricating bone replacements
US5084051A (en) * 1986-11-03 1992-01-28 Toermaelae Pertti Layered surgical biocomposite material
US4904261A (en) * 1987-08-06 1990-02-27 A. W. Showell (Surgicraft) Limited Spinal implants
US5593409A (en) * 1988-06-13 1997-01-14 Sofamor Danek Group, Inc. Interbody spinal fusion implants
US5609635A (en) * 1988-06-28 1997-03-11 Michelson; Gary K. Lordotic interbody spinal fusion implants
US5108438A (en) * 1989-03-02 1992-04-28 Regen Corporation Prosthetic intervertebral disc
US5281226A (en) * 1989-03-31 1994-01-25 Davydov Anatoly B Missing portion of a tubular bone
US4994084A (en) * 1989-06-23 1991-02-19 Brennan H George Reconstructive surgery method and implant
US5489308A (en) * 1989-07-06 1996-02-06 Spine-Tech, Inc. Spinal implant
US5298254A (en) * 1989-09-21 1994-03-29 Osteotech, Inc. Shaped, swollen demineralized bone and its use in bone repair
US5284655A (en) * 1989-09-21 1994-02-08 Osteotech, Inc. Swollen demineralized bone particles, flowable osteogenic composition containing same and use of the composition in the repair of osseous defects
US5085660A (en) * 1990-11-19 1992-02-04 Lin Kwan C Innovative locking plate system
US5192327A (en) * 1991-03-22 1993-03-09 Brantigan John W Surgical prosthetic implant for vertebrae
US5290312A (en) * 1991-09-03 1994-03-01 Alphatec Artificial vertebral body
US5275601A (en) * 1991-09-03 1994-01-04 Synthes (U.S.A) Self-locking resorbable screws and plates for internal fixation of bone fractures and tendon-to-bone attachment
US5180381A (en) * 1991-09-24 1993-01-19 Aust Gilbert M Anterior lumbar/cervical bicortical compression plate
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
US5607474A (en) * 1992-02-14 1997-03-04 Board Of Regents, University Of Texas System Multi-phase bioerodible implant/carrier and method of manufacturing and using same
US5616144A (en) * 1992-11-25 1997-04-01 Codman & Shurtleff, Inc. Osteosynthesis plate system
US5405391A (en) * 1993-02-16 1995-04-11 Hednerson; Fraser C. Fusion stabilization chamber
US5609637A (en) * 1993-07-09 1997-03-11 Biedermann; Lutz Space keeper, in particular for an intervertebral disk
US5888224A (en) * 1993-09-21 1999-03-30 Synthesis (U.S.A.) Implant for intervertebral space
US5397364A (en) * 1993-10-12 1995-03-14 Danek Medical, Inc. Anterior interbody fusion device
US6364880B1 (en) * 1994-03-28 2002-04-02 Gary Karlin Michelson Spinal implant with bone screws
US5609636A (en) * 1994-05-23 1997-03-11 Spine-Tech, Inc. Spinal implant
US5507818A (en) * 1994-06-30 1996-04-16 Mclaughlin; John A. Multipolar joint endoprosthesis
US5885299A (en) * 1994-09-15 1999-03-23 Surgical Dynamics, Inc. Apparatus and method for implant insertion
US6033405A (en) * 1994-09-15 2000-03-07 Surgical Dynamics, Inc. Apparatus and method for implant insertion
US5601553A (en) * 1994-10-03 1997-02-11 Synthes (U.S.A.) Locking plate and bone screw
US6206922B1 (en) * 1995-03-27 2001-03-27 Sdgi Holdings, Inc. Methods and instruments for interbody fusion
US6695851B2 (en) * 1995-03-27 2004-02-24 Sdgi Holdings, Inc. Methods and instruments for interbody fusion
US5876402A (en) * 1995-04-13 1999-03-02 Errico; Joseph P. Anterior spinal polyaxial locking screw plate assembly having recessed retaining rings
US5713899A (en) * 1995-04-27 1998-02-03 Societe Jbs Sa Cervical cage designed for the performance of intersomatic arthrodesis
US5735905A (en) * 1995-04-27 1998-04-07 Southwest Research Institute Shock absorbing element for a load bearing prosthesis
US5865849A (en) * 1995-06-07 1999-02-02 Crosscart, Inc. Meniscal heterografts
US6039762A (en) * 1995-06-07 2000-03-21 Sdgi Holdings, Inc. Reinforced bone graft substitutes
US5888222A (en) * 1995-10-16 1999-03-30 Sdgi Holding, Inc. Intervertebral spacers
US5888227A (en) * 1995-10-20 1999-03-30 Synthes (U.S.A.) Inter-vertebral implant
US5888223A (en) * 1995-12-08 1999-03-30 Bray, Jr.; Robert S. Anterior stabilization device
US5865845A (en) * 1996-03-05 1999-02-02 Thalgott; John S. Prosthetic intervertebral disc
US5895426A (en) * 1996-09-06 1999-04-20 Osteotech, Inc. Fusion implant device and method of use
US6045580A (en) * 1996-09-06 2000-04-04 Osteotech, Inc. Fusion implant device and method of use
US5872915A (en) * 1996-12-23 1999-02-16 International Business Machines Corporation Computer apparatus and method for providing security checking for software applications accessed via the World-Wide Web
US5728159A (en) * 1997-01-02 1998-03-17 Musculoskeletal Transplant Foundation Serrated bone graft
US6712818B1 (en) * 1997-02-11 2004-03-30 Gary K. Michelson Method for connecting adjacent vertebral bodies of a human spine with a plating system
US6193721B1 (en) * 1997-02-11 2001-02-27 Gary K. Michelson Multi-lock anterior cervical plating system
US5861041A (en) * 1997-04-07 1999-01-19 Arthit Sitiso Intervertebral disk prosthesis and method of making the same
US6855168B2 (en) * 1997-04-25 2005-02-15 Stryker France Intersomatic implants in two parts
US6045579A (en) * 1997-05-01 2000-04-04 Spinal Concepts, Inc. Adjustable height fusion device
US6033438A (en) * 1997-06-03 2000-03-07 Sdgi Holdings, Inc. Open intervertebral spacer
US6193756B1 (en) * 1997-09-30 2001-02-27 Sulzer Orthopaedie Ag Tubular support body for bridging two vertebrae
US6679887B2 (en) * 1998-05-06 2004-01-20 Cortek, Inc. Surgical procedure for implanting spinal fusion device
US20020029084A1 (en) * 1998-08-03 2002-03-07 Paul David C. Bone implants with central chambers
US7001385B2 (en) * 1998-08-20 2006-02-21 Bonutti Ip, Llc Joint spacer with compartment for orthobiologic material
US6371986B1 (en) * 1998-10-27 2002-04-16 George W. Bagby Spinal fusion device, bone joining implant, and vertebral fusion implant
US6025538A (en) * 1998-11-20 2000-02-15 Musculoskeletal Transplant Foundation Compound bone structure fabricated from allograft tissue
US6200347B1 (en) * 1999-01-05 2001-03-13 Lifenet Composite bone graft, method of making and using same
US6342074B1 (en) * 1999-04-30 2002-01-29 Nathan S. Simpson Anterior lumbar interbody fusion implant and method for fusing adjacent vertebrae
US20020016595A1 (en) * 1999-05-05 2002-02-07 Gary K. Michelson Screws of cortical bone and method of manufacture thereof
US20020022843A1 (en) * 1999-05-05 2002-02-21 Michelson Gary K. Screws of cortical bone and method of manufacture thereof
US20030078668A1 (en) * 1999-05-05 2003-04-24 Michelson Gary K. Interbody spinal fusion implants with single-lock for locking opposed screws
US20050033433A1 (en) * 1999-05-05 2005-02-10 Michelson Gary K. Implant having upper and lower extended members and method for use thereof
US6524312B2 (en) * 2000-01-06 2003-02-25 Spinal Concepts, Inc. Instrument and method for implanting an interbody fusion device
US6709456B2 (en) * 2000-01-31 2004-03-23 Ev3 Santa Rosa, Inc. Percutaneous mitral annuloplasty with hemodynamic monitoring
US20050065608A1 (en) * 2000-02-04 2005-03-24 Michelson Gary K. Expandable threaded arcuate interbody spinal fusion implant with lordotic configuration during insertion
US20020010511A1 (en) * 2000-07-07 2002-01-24 Michelson Gary Karlin Expandable implant with interlocking walls
US20020004683A1 (en) * 2000-07-10 2002-01-10 Michelson Gary K. Flanged interbody spinal fusion implants
US7163561B2 (en) * 2000-07-10 2007-01-16 Warsaw Orthopedic, Inc. Flanged interbody spinal fusion implants
US7172672B2 (en) * 2000-11-20 2007-02-06 Silverbrook Research Pty Ltd Method of adhesively binding a stack of sheets
US6503250B2 (en) * 2000-11-28 2003-01-07 Kamaljit S. Paul Bone support assembly
US20050015149A1 (en) * 2001-02-04 2005-01-20 Michelson Gary K. Instrumentation with inwardly moveable extensions for inserting an expandable interbody spinal fusion implant
US6849093B2 (en) * 2001-03-09 2005-02-01 Gary K. Michelson Expansion constraining member adapted for use with an expandable interbody spinal fusion implant and method for use thereof
US7172627B2 (en) * 2001-04-03 2007-02-06 Scient'x Stabilized interbody fusion system for vertebrae
US20030078666A1 (en) * 2001-10-18 2003-04-24 Ralph James D. Intervertebral spacer device having a slotted partial circular domed arch strip spring
US7238203B2 (en) * 2001-12-12 2007-07-03 Vita Special Purpose Corporation Bioactive spinal implants and method of manufacture thereof
US7875076B2 (en) * 2002-02-19 2011-01-25 Synthes Usa, Llc Intervertebral implant
US6682563B2 (en) * 2002-03-04 2004-01-27 Michael S. Scharf Spinal fixation device
US6695846B2 (en) * 2002-03-12 2004-02-24 Spinal Innovations, Llc Bone plate and screw retaining mechanism
US7001432B2 (en) * 2002-03-12 2006-02-21 Cervitech, Inc. Intervertebral prosthesis
US20040078081A1 (en) * 2002-09-09 2004-04-22 Ferree Bret A. Bioresorbable components and methods for spinal arthroplasty
US6837905B1 (en) * 2002-09-26 2005-01-04 Daniel M. Lieberman Spinal vertebral fusion implant and method
US7323011B2 (en) * 2002-10-18 2008-01-29 Musculoskeletal Transplant Foundation Cortical and cancellous allograft cervical fusion block
US20040078078A1 (en) * 2002-10-18 2004-04-22 Shepard Yolanda Denise Cortical and cancellous allograft cervical fusion block
US7320708B1 (en) * 2002-11-13 2008-01-22 Sdgi Holdings, Inc. Cervical interbody device
US7862616B2 (en) * 2003-02-06 2011-01-04 Synthes Usa, Llc Intervertebral implant
US20050085913A1 (en) * 2003-03-31 2005-04-21 Robert Fraser Spinal fixation plate
US20060030851A1 (en) * 2003-04-21 2006-02-09 Rsb Spine Llc Implant subsidence control
US6984234B2 (en) * 2003-04-21 2006-01-10 Rsb Spine Llc Bone plate stabilization system and method for its use
US20050021143A1 (en) * 2003-07-22 2005-01-27 Cervitech, Inc. Intervertebral disc prosthesis
US20050049593A1 (en) * 2003-09-03 2005-03-03 Duong Lan Anh Nguyen Bone plate with captive clips
US20050049595A1 (en) * 2003-09-03 2005-03-03 Suh Sean S. Track-plate carriage system
US20050071008A1 (en) * 2003-09-30 2005-03-31 Kirschman David Louis Spinal fusion system and method for fusing spinal bones
US8343222B2 (en) * 2005-04-28 2013-01-01 Aiden Cope Spinal disc prosthesis and instruments
US20100016901A1 (en) * 2005-06-16 2010-01-21 Robinson James C Bone screw retaining system
US20080051890A1 (en) * 2006-08-11 2008-02-28 Warsaw Orthopedic, Inc. Intervertebral Implants with Attachable Flanges and Methods of Use
US20090076608A1 (en) * 2007-09-17 2009-03-19 Vermillion Technologies, Llc Intervertebral disc replacement prosthesis

Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9333095B2 (en) 2001-05-04 2016-05-10 Ldr Medical Intervertebral disc prosthesis, surgical methods, and fitting tools
US9078765B2 (en) 2001-07-13 2015-07-14 Ldr Medical Vertebral cage device with modular fixation
US9572681B2 (en) 2002-02-19 2017-02-21 DePuy Synthes Products, Inc. Intervertebral implant
US8267999B2 (en) 2002-11-05 2012-09-18 Ldr Medical Intervertebral disc prosthesis
US9463097B2 (en) 2003-02-06 2016-10-11 DePuy Synthes Products, Inc. Intervertebral implant
US9039775B2 (en) 2003-03-31 2015-05-26 DePuy Synthes Products, Inc. Spinal fixation plates
US9320549B2 (en) 2003-03-31 2016-04-26 DePuy Synthes Products, Inc. Spinal fixation plates
US8858635B2 (en) 2004-02-04 2014-10-14 Ldr Medical Intervertebral disc prosthesis
US8974532B2 (en) 2004-04-28 2015-03-10 Ldr Medical Intervertebral disc prosthesis
US8257439B2 (en) 2004-12-22 2012-09-04 Ldr Medical Intervertebral disc prosthesis
US8979932B2 (en) 2005-09-23 2015-03-17 Ldr Medical Intervertebral disc prosthesis
US8771284B2 (en) 2005-11-30 2014-07-08 Ldr Medical Intervertebral disc prosthesis and instrumentation for insertion of the prosthesis between the vertebrae
US9713535B2 (en) 2006-02-15 2017-07-25 Ldr Medical Transforaminal intersomatic cage for an intervertebral fusion graft and an instrument for implanting the cage
US8465546B2 (en) 2007-02-16 2013-06-18 Ldr Medical Intervertebral disc prosthesis insertion assemblies
US8343219B2 (en) 2007-06-08 2013-01-01 Ldr Medical Intersomatic cage, intervertebral prosthesis, anchoring device and implantation instruments
US9005295B2 (en) 2007-11-16 2015-04-14 DePuy Synthes Products, LLC Low profile intervertebral implant
US9744049B2 (en) 2007-11-16 2017-08-29 DePuy Synthes Products, Inc. Low profile intervertebral implant
US9402735B2 (en) 2008-11-07 2016-08-02 DePuy Synthes Products, Inc. Zero-profile interbody spacer and coupled plate assembly
US9192419B2 (en) 2008-11-07 2015-11-24 DePuy Synthes Products, Inc. Zero-profile interbody spacer and coupled plate assembly
US9414935B2 (en) 2008-11-07 2016-08-16 DePuy Synthes Products, Inc. Zero-profile interbody spacer and coupled plate assembly
US9592129B2 (en) 2009-03-30 2017-03-14 DePuy Synthes Products, Inc. Zero profile spinal fusion cage
US9526620B2 (en) 2009-03-30 2016-12-27 DePuy Synthes Products, Inc. Zero profile spinal fusion cage
US9463091B2 (en) 2009-09-17 2016-10-11 Ldr Medical Intervertebral implant having extendable bone fixation members
US9044337B2 (en) 2009-12-31 2015-06-02 Ldr Medical Anchoring device and system for an intervertebral implant, intervertebral implant and implantation instrument
US9833331B2 (en) 2009-12-31 2017-12-05 Ldr Medical Anchoring device and system for an intervertebral implant, intervertebral implant and implantation instrument
US9241809B2 (en) 2010-12-21 2016-01-26 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
US9848992B2 (en) 2010-12-21 2017-12-26 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
US9220604B2 (en) 2010-12-21 2015-12-29 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use
US9039774B2 (en) 2012-02-24 2015-05-26 Ldr Medical Anchoring device and system for an intervertebral implant, intervertebral implant and implantation instrument
US9693876B1 (en) * 2012-03-30 2017-07-04 Ali H. MESIWALA Spinal fusion implant and related methods
US9539043B2 (en) 2013-03-13 2017-01-10 Ebi, Llc Screw driver, combination, and related methods
US9877842B2 (en) 2014-01-30 2018-01-30 Ldr Medical Anchoring device for a spinal implant, spinal implant and implantation instrumentation
US9867718B2 (en) 2014-10-22 2018-01-16 DePuy Synthes Products, Inc. Intervertebral implants, systems, and methods of use

Also Published As

Publication number Publication date Type
EP1476098A1 (en) 2004-11-17 application
CA2478581C (en) 2010-01-19 grant
US9572681B2 (en) 2017-02-21 grant
US20120109313A1 (en) 2012-05-03 application
US20120109310A1 (en) 2012-05-03 application
US20120101581A1 (en) 2012-04-26 application
KR100882602B1 (en) 2009-02-12 grant
DE50212036D1 (en) 2008-05-15 grant
WO2003070128A8 (en) 2004-10-14 application
EP1476098B1 (en) 2008-04-02 grant
CN100400014C (en) 2008-07-09 grant
US7875076B2 (en) 2011-01-25 grant
ES2304428T3 (en) 2008-10-16 grant
JP4220395B2 (en) 2009-02-04 grant
KR20040091652A (en) 2004-10-28 application
US20070219635A1 (en) 2007-09-20 application
US7232464B2 (en) 2007-06-19 grant
CA2478581A1 (en) 2003-08-28 application
US20120109309A1 (en) 2012-05-03 application
CN1620271A (en) 2005-05-25 application
US20120109312A1 (en) 2012-05-03 application
JP2005517492A (en) 2005-06-16 application
US20050177236A1 (en) 2005-08-11 application
US20170143509A1 (en) 2017-05-25 application
US7618456B2 (en) 2009-11-17 grant
US20100094421A1 (en) 2010-04-15 application
US20120109311A1 (en) 2012-05-03 application
WO2003070128A1 (en) 2003-08-28 application

Similar Documents

Publication Publication Date Title
US6800092B1 (en) Method and apparatus for intervertebral implant anchorage
USRE37479E1 (en) Spinal fixation device
US6099529A (en) Allograft bone fixation screw method and apparatus
US5620443A (en) Anterior screw-rod connector
US4904261A (en) Spinal implants
US6261291B1 (en) Orthopedic implant assembly
US7341589B2 (en) Bone plating system
US6689168B2 (en) Method and apparatus for stabilizing adjacent bones
US6432140B1 (en) Intervertebral retrieval device
US20050096652A1 (en) Integral flexible spine stabilization device and method
US20020111680A1 (en) Ratcheted bone dowel
US20020055737A1 (en) Apparatus for implantation into bone related applications
US20070106384A1 (en) Implant subsidence control
US6136001A (en) Apparatus and method for linking spinal implants
US20070250167A1 (en) Spine implants
US20030181913A1 (en) Apparatus for implantation into bone
US20090030520A1 (en) Fixation device for bones
EP0551187A1 (en) Apparatus for use in fusion of adjacent spinal bodies
US7682379B2 (en) Device for osteosynthesis
US7879036B2 (en) Bone anchoring element
US5368593A (en) Devices and methods for attachment of spine fixation devices
US8216312B2 (en) Spinal interbody system and method
US20090036986A1 (en) Attachment devices and methods for spinal implants
US7922765B2 (en) Systems and methods for the fixation or fusion of bone
US20020120271A1 (en) Method and device for using extended interference fit screw shanks for spinal stabilization

Legal Events

Date Code Title Description
AS Assignment

Owner name: DEPUY SPINE, LLC, MASSACHUSETTS

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SYNTHES USA, LLC;REEL/FRAME:030358/0945

Effective date: 20121230

Owner name: HAND INNOVATIONS LLC, FLORIDA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:DEPUY SPINE, LLC;REEL/FRAME:030359/0001

Effective date: 20121230

Owner name: DEPUY SYNTHES PRODUCTS, LLC, MASSACHUSETTS

Free format text: CHANGE OF NAME;ASSIGNOR:HAND INNOVATIONS LLC;REEL/FRAME:030359/0036

Effective date: 20121231

AS Assignment

Owner name: SYNTHES USA, LLC, PENNSYLVANIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SYNTHES GMBH;REEL/FRAME:032142/0934

Effective date: 20090701

Owner name: SYNTHES (USA), PENNSYLVANIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:MATHIEU, CLAUDE;CAIN, CHRISTOPHER MARDEN JOHN;SIGNING DATES FROM 20040709 TO 20050512;REEL/FRAME:032142/0798

Owner name: SYNTHES GMBH, SWITZERLAND

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SYNTHES (USA);REEL/FRAME:032142/0885

Effective date: 20051227

Owner name: SYNTHES USA, LLC, PENNSYLVANIA

Free format text: CHANGE OF NAME;ASSIGNOR:SYNTHES (U.S.A.);REEL/FRAME:032142/0849

Effective date: 20081231

AS Assignment

Owner name: DEPUY SYNTHES PRODUCTS, INC., MASSACHUSETTS

Free format text: CHANGE OF NAME;ASSIGNOR:DEPUY SYNTHES PRODUCTS, LLC;REEL/FRAME:036206/0592

Effective date: 20141219

AS Assignment

Owner name: HAND INNOVATIONS LLC, FLORIDA

Free format text: CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT APPL. NO. 13/486,591 PREVIOUSLY RECORDED AT REEL: 030359 FRAME: 0001. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT;ASSIGNOR:DEPUY SPINE, LLC;REEL/FRAME:042621/0565

Effective date: 20121230

AS Assignment

Owner name: DEPUY SPINE, LLC, MASSACHUSETTS

Free format text: CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT APPLICATION NO. US 13/486,591 PREVIOUSLY RECORDED ON REEL 030358 FRAME 0945. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT;ASSIGNOR:SYNTHES USA, LLC;REEL/FRAME:042687/0849

Effective date: 20121230