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Method For Replacing Native Valve Function Of A Diseased Aortic Valve

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Publication number
US20100217384A1
US20100217384A1 US12776136 US77613610A US20100217384A1 US 20100217384 A1 US20100217384 A1 US 20100217384A1 US 12776136 US12776136 US 12776136 US 77613610 A US77613610 A US 77613610A US 20100217384 A1 US20100217384 A1 US 20100217384A1
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Prior art keywords
valve
manipulation
instrument
prosthesis
aortic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12776136
Inventor
John R. Liddicoat
Gregory H. Lambrecht
Todd F. Davenport
William E. Cohn
Steven B. Woolfson
Daniel C. Taylor
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Medtronic Vascular Inc
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Medtronic Vascular Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • A61F2/2427Devices for manipulating or deploying heart valves during implantation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/902Method of implanting

Abstract

Methods for replacing native valve function of a diseased aortic valve are disclosed. In an embodiment, a method for replacing native valve function of a diseased aortic valve in a patient includes: (a) receiving an artificial heart valve assembly mounted about a first mounting position on a catheter system, (b) guiding the artificial heart valve assembly through the vasculature of the patient, (c) while the catheter system having the artificial heart valve assembly mounted thereto is in the patient's vasculature, mounting the artificial heart valve assembly about a second mounting position on the catheter system, (d) delivering the artificial heart valve assembly to the region of the diseased aortic valve, (e) expanding the artificial heart valve assembly in the region of the diseased aortic valve, and (f) withdrawing the catheter system from the patient's vasculature.

Description

    CROSS REFERENCE TO RELATED APPLICATIONS
  • [0001]
    The present application is a continuation of U.S. patent application Ser. No. 10/895,272, filed Jul. 20, 2004, which is a continuation of U.S. patent application Ser. No. 09/896,259, filed Jun. 29, 2001, now U.S. Pat. No. 6,769,434, which claims priority to U.S. Provisional Pat. App. No. 60/215,245, filed Jun. 30, 2000.
  • BACKGROUND OF THE INVENTION
  • [0002]
    Of all valvular heart lesions, aortic stenosis carries the worst prognosis. Within one year of diagnosis, approximately half of all patients with critical aortic stenosis have died, and by three years, this figure rises to approximately 80%. Currently, the most prominent and effective treatment for patients with aortic stenosis is aortic valve replacement via open heart surgery. Unfortunately, this procedure is a substantial and invasive undertaking for the patient.
  • [0003]
    While there have been significant advances in heart valve technology over the past 30 years, there has been little progress in the development of safer and less invasive valve delivery systems. Aortic valve replacement currently requires a sternotomy or thoracotomy, use of cardiopulmonary bypass to arrest the heart and lungs, and a large incision on the aorta. The native valve is resected through this incision and then a prosthetic valve is sutured to the inner surface of the aorta with a multitude of sutures passing only partly into the wall of the aorta. Given the current invasiveness of this procedure and the requirement to utilize cardiopulmonary bypass, aortic valve replacement surgery is associated with a high risk of morbidity and mortality. This is especially true in elderly patients, and in those patients who require concomitant coronary artery bypass grafting. Even when a good surgical result is achieved, virtually all patients require approximately 6 weeks to several months to fully recover from the procedure. In order to decrease these associated risks of aortic valve surgery, many have pursued novel approaches and technologies.
  • [0004]
    Less invasive approaches to aortic valve surgery have generally followed two paths.
  • [0005]
    In the 1980's, there was a flurry of interest in percutaneous balloon valvotomy. In this procedure, a cardiologist introduced a catheter through the femoral artery to dilate the patient's aortic valve, thereby relieving the stenosis. Using the technology available at that time, success was limited: the valve area was increased only minimally, and nearly all patients had restenosis within one year.
  • [0006]
    More recently, surgeons have approached the aortic valve via smaller chest wall incisions. However, these approaches still require cardiopulmonary bypass and cardiac arrest, which themselves entail significant morbidity and a prolonged post-operative recovery.
  • [0007]
    The ideal minimally invasive approach to the treatment of aortic valve disease requires aortic valve replacement without cardiopulmonary bypass and without cardiac arrest. Such an approach would greatly reduce patient morbidity and mortality and hasten recovery. Unfortunately, although there has been great progress in the treatment of coronary artery disease without cardiopulmonary bypass (e.g., angioplasty, with or without stenting, and “off-pump” coronary artery bypass grafting), similar advances have not yet been realized in heart valve surgery. With an aging population and improved access to advanced diagnostic testing, the incidence and accurate diagnosis of aortic stenosis will continue to increase. The development of a system for “off-pump” aortic valve replacement would be of significant benefit to this increasing patient population.
  • [0008]
    There are three important challenges to replacing a diseased aortic valve without cardiopulmonary bypass.
  • [0009]
    The first challenge is to remove the diseased valve without causing stroke or other ischemic events that might result from the liberation of particulate material while removing the diseased valve.
  • [0010]
    The second challenge is to prevent cardiac failure during removal of the diseased valve. In this respect it must be appreciated that the aortic valve continues to serve a critical function even when it is diseased. However, as the diseased valve is removed, it becomes acutely and severely incompetent, causing the patient to develop heart failure which results in death unless the function of the valve is taken over by another means.
  • [0011]
    The third challenge is placing a prosthetic valve into the vascular system and affixing it to the wall of the aorta. More particularly, during cardiac rhythm, the aortic and arterial pressures are substantially greater than atmospheric pressure. Therefore, any sizable incision made to the aorta in order to insert a standard valve prosthesis into the arterial system creates the potential for uncontrollable bleeding from the incision site. Furthermore, even if bleeding is successfully controlled, pressures within the aorta may result in weakening of the aorta caused by aortic wall dissection. In addition, large incisions on the aorta also increase the potential for liberating plaque from the aortic wall that can lead to embolic complications.
  • [0012]
    For these reasons, prior art valve prostheses potentially suitable for off-pump implantation have relied upon relatively flimsy expandable structures to support and secure the valve within the aorta. More particularly, these prosthetic valves are constructed so that they can be compressed to a relatively small dimension suitable for insertion into the arterial system, advanced to the site of the aortic valve, and then expanded against the aortic wall. Unfortunately, however, none of these relatively flimsy valve prostheses have proven adequate to endure the repetitive stresses undergone by the aortic valve over the ten to twenty years typically required.
  • [0013]
    In addition to the foregoing, the precise placement of such expandable prosthetic valves in the correct sub-coronary position can be extremely challenging, particularly in view of the high pressure, pulsatile blood flow passing through the aorta. Furthermore, expandable prosthetic valves would typically be positioned from a remote artery, which would reduce the ability to precisely control the placement and positioning of the device and therefore would increases the risk of obstructing the coronary arteries. The expandable prosthetic valves are held on the ends of elongate, flexible catheters that are threaded into the aorta, around the aortic arch and then expanded. The pulsatile flow during cardiac rhythm induces a to-and-fro motion of the valve prosthesis relative to the aorta that makes the timing of valve expansion critical for proper placement of the expandable prosthetic valve and hence the survival of the patient.
  • [0014]
    Finally, many of the challenges discussed in the foregoing section pertaining to aortic valve replacement are also relevant to other procedures in the aortic root such as aortic valve resection, aortic valve decalcification, stent grafting for aortic dissections, etc.
  • SUMMARY OF THE INVENTION
  • [0015]
    It is, therefore, one object of the present invention to enable the passage of a device from the left atrium, through the left ventricle, and into the arterial system.
  • [0016]
    Further, another object of the present invention is to enable the implantation of a device in the arterial system without cardiopulmonary bypass.
  • [0017]
    Further, another object of the present invention is to enable the implantation of a prosthetic valve in the arterial system without cardiopulmonary bypass.
  • [0018]
    Another object of the present invention is to allow the insertion of such a valve while minimizing the risks to the patient posed by large arterial incisions.
  • [0019]
    And another object of the present invention is to simplify the precise placement of such a valve.
  • [0020]
    Further, another object of the present invention is to enable the implantation of a device other than a valve, such as but not limited to a valve resection tool, a decalcifying tool, an aortic valve repair tool, or a stented aortic graft, in the arterial system without cardiopulmonary bypass.
  • [0021]
    Another object of the present invention is to allow the insertion of a device other than a valve, such as but not limited to a valve resection tool, a decalcifying tool, an aortic valve repair tool, or a stented aortic graft, while minimizing the risks to the patient posed by large arterial incisions.
  • [0022]
    And another object of the present invention is to simplify the precise placement of a device other than a valve, such as but not limited to a valve resection tool, a decalcifying tool, an aortic valve repair tool, or a stented aortic graft.
  • [0023]
    The present invention relates to a method and apparatus for positioning a device in the arterial system. More specifically, the present invention relates to a method and apparatus for positioning an aortic valve prosthesis in the aorta or aortic outflow tract, with or without cardiopulmonary bypass.
  • [0024]
    One aspect of the present invention is a method for deploying an aortic valve prosthesis. This valve prosthesis may include any of the known aortic valves including, but not limited to, stented and unstented bioprosthetic valves, stented mechanical valves, and expandable or self-expanding valves, whether biological or artificial.
  • [0025]
    In one aspect of the invention, there is provided a method of inserting a prosthesis or device from a lower pressure region into a higher pressure region of the cardiovascular system comprising the steps of: making an opening in a wall of a lower pressure region of the cardiovascular system; advancing the prosthesis or device through the opening and into the lower pressure region; and advancing the prosthesis or device through a natural barrier between the lower pressure region and the higher pressure region.
  • [0026]
    In another aspect of the invention, there is provided a method of inserting a prosthesis or device into a vessel within the arterial system comprising the steps of: making an opening in a wall of a low pressure region of the heart; advancing the prosthesis or device through the opening and into the low pressure region; advancing the prosthesis or device through a natural barrier between the low pressure region and the left ventricle; and advancing the prosthesis or device from the left ventricle into the arterial system and the vessel.
  • [0027]
    And in another aspect of the invention, there is provided a method of inserting a prosthesis or device into a vessel within the arterial system comprising the steps of: making an opening in a wall of the left atrium; advancing the prosthesis or device through the opening and into the left atrium; advancing the prosthesis or device through the mitral valve and into the left ventricle; and advancing the prosthesis or device from the left ventricle into the arterial system and the vessel.
  • [0028]
    And in another aspect of the present invention, there is provided a method for positioning a device in the arterial system comprising the steps of: making a first opening leading to the left atrium; passing a valve prosthesis through the first opening and into a cardiac chamber of the left side of the heart using a first manipulation instrument; making a second opening in the arterial system and advancing one end of a second manipulation instrument through the second opening and into the aforementioned cardiac chamber; securing the second manipulation instrument to the valve prosthesis; and then using the second manipulation instrument to retract at least some portion of the valve prosthesis out of the aforementioned cardiac chamber.
  • [0029]
    An alternative method for positioning a device in the arterial system comprises the steps of: making an opening leading to the left atrium; passing a valve prosthesis through the opening and into a cardiac chamber of the left side of the heart using an articulating manipulation instrument; using the articulating manipulation instrument to guide the valve prosthesis into the arterial cardiac chamber; releasing the valve prosthesis into a desired position: and then retracting at least a portion of the articulating manipulation instrument out of the aforementioned cardiac chamber and left atrium.
  • [0030]
    The pressure of blood flowing through the left atrium is very low, peaking at a few inches of water during the cardiac cycle. This pressure is a small fraction of that found within the arterial system and thus permits insertion of a conventional valve prosthesis through a relatively large opening formed in the wall of the left atrium without the risk of uncontrollable bleeding. In this respect it will be appreciated that various methods are known to those skilled in the art for controlling bleeding from an incision into the left atrium. The left atrium also rarely suffers from atherosclerotic plaque formation or calcification, thus minimizing the risk of embolic debris during such incision.
  • [0031]
    Another aspect of the present invention is the use of a prosthesis holding apparatus for releasably holding the valve prosthesis during manipulation to its implant site. The prosthesis holding apparatus may be secured to the prosthetic valve at any suitable location(s) through the use of any of a variety of approaches including, but not limited to, suture loops, barbs, hooks, grasping jaws, opposing magnetic poles, friction fits and the like. The prosthesis holding apparatus is configured to provides first and second manipulation mounts for engagement by the aforementioned first and second manipulation instruments, respectively, whereby the prosthetic valve can be delivered to its implant site. This construction is highly advantageous in that it permits the valve prosthesis to be passed easily and reliably from the first manipulation instrument to the second manipulation instrument within the vascular system.
  • [0032]
    In an alternative preferred embodiment, the prosthetic holding apparatus is attached on the ventricular side of the prosthesis. The aforementioned first manipulation instrument would articulate at or near the prosthetic valve to facilitate manipulation of the prosthesis holding apparatus (and hence the prosthesis itself) through the smallest possible incision site, then through the left atrium, the mitral valve and within the heart to align and position the prosthesis within the aortic annulus or left ventricular outflow track. In this alternative embodiment, there is no need for the aforementioned second manipulation instrument or the second manipulation mount.
  • [0033]
    In addition, if the prosthesis holding apparatus is attached on the aortic side of the prosthesis, the manipulation instrument may articulate and may be introduced into the arterial system, brought across the mitral valve into the left atrium, out the left atrium to pick up the prosthesis holding apparatus (and hence the prosthesis) and then retracted back to position the prosthesis directly into the aortic annulus without the need for another manipulation instrument.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0034]
    These and other objects and features of the present invention will be more fully disclosed or rendered obvious by the following detailed description of the preferred embodiments of the invention, which is to be considered together with the accompanying drawings wherein like numbers refer to like elements and further wherein:
  • [0035]
    FIG. 1 is a schematic side view showing the introduction of a valve prosthesis and prosthesis holding apparatus into the left atrium of the heart, through an atriotomy, using a first manipulation instrument;
  • [0036]
    FIG. 2 is a schematic side view showing passage of the apparatus of FIG. 1 from the left atrium, through the mitral valve, and into the left ventricle;
  • [0037]
    FIG. 3 is a schematic side view showing the introduction of a second manipulation instrument into the left ventricle through an arteriotomy into the arterial system;
  • [0038]
    FIG. 4 is a schematic side view showing the second manipulation instrument being attached to the prosthesis holding apparatus while the first manipulation instrument remains secured to the prosthesis holding apparatus;
  • [0039]
    FIG. 5 is a schematic side view similar to that of FIG. 4, except showing the first manipulation instrument being removed from the surgical site while the second manipulation instrument remains secured to the prosthesis holding apparatus;
  • [0040]
    FIG. 6 is a schematic side view showing the second manipulation instrument positioning the prosthetic valve within the aorta prior to fixation;
  • [0041]
    FIG. 7 is a schematic side view showing the prosthetic valve secured to the tissues of the aorta following removal of the second manipulation instrument and prosthesis holding apparatus;
  • [0042]
    FIGS. 8, 9 and 10 are enlarged schematic views showing a preferred construction for the valve holding apparatus, and for the attachment to, and detachment from, the prosthetic valve; and
  • [0043]
    FIG. 11 is a schematic view showing a guide for guiding the second manipulation instrument relative to the first manipulation instrument such that the second manipulation instrument will be aimed directly at the second manipulation mount when the first manipulation mount is secured to the first manipulation instrument.
  • DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
  • [0044]
    The present invention can be used to implant a variety of prostheses into the arterial system or left side of the heart. The prosthesis used in the preferred embodiment is an aortic valve prosthesis. Alternatively, the prosthesis may comprise, but is not limited to, a cylindrical arterial stent, an arterial prosthesis or graft, a ventricular assist device, a device for the treatment of heart failure such as an intraventricular counterpulsation balloon, chordae tendinae prostheses, arterial filters suitable for acute or chronic filtration of emboli from the blood stream, arterial occlusion devices and the like.
  • [0045]
    For clarity of illustration, the present invention will hereinafter be discussed in the context of implanting an aortic valve prosthesis.
  • [0046]
    It should also be appreciated that the present invention may be practiced either “on-pump” or “off-pump”. In other words, the present invention may be performed either with or without the support of cardiopulmonary bypass. The present invention also may be performed either with or without cardiac arrest.
  • [0047]
    Looking now at FIG. 1, there is shown an exemplary embodiment of the present invention. A prothesis holding apparatus 100 is secured to a prosthetic valve 200 so as to form a temporary prosthetic assembly 300. A first manipulation instrument 400 is secured to a first manipulation mount 105 formed on prosthesis holding apparatus 100, whereby temporary prosthetic assembly 300 may be moved about by first manipulation instrument 400. Temporary prosthetic assembly 300 has been positioned in left atrium 5 by passing first manipulation instrument 400 through atriotomy 10. Alternatively, the temporary prosthetic assembly 300 could be passed into the left atrium 5, using first manipulation instrument 400, through any of the pulmonary veins 15. And in another form of the invention, temporary prosthesis assembly 300 could be passed into the left atrium by first passing the assembly into the right atrium via an atriotomy, and then into the left atrium through an incision made in the interatrial septum.
  • [0048]
    Prosthetic valve 200 is preferably a conventional mechanical aortic valve of the sort well known in the art, although other forms of valve prostheses may also be used.
  • [0049]
    In one preferred form of the invention, first manipulation instrument 400 functions by virtue of the relative motion of an outer cannula 405 relative to an inner grasper 410. More particularly, inner grasper 410 has an elastically deformable distal gripper 415 which is open when the gripper is outside of outer cannula 405. However, when deformable gripper 415 is pulled at least partially into or against outer cannula 405, gripper 415 is elastically deformed into a closed position, whereby it may grip an object, e.g., first manipulation mount 105 formed on prosthesis holding apparatus 100. First manipulation instrument 400 is shown in FIG. 1 in its closed position, wherein deformable gripper 415 is closed about first manipulation mount 105, such that prosthesis holding apparatus 100, and hence the entire temporary prosthetic assembly 300, is held secured to the distal end of first manipulation instrument 400.
  • [0050]
    The specific embodiment of first manipulation instrument 400 shown in FIG. 1 is presented as an illustrative example only, and is not intended to limit the scope of the present invention. Many other arrangements may be used for releasably gripping first manipulation mount 105 formed on prosthesis holding apparatus 100. Furthermore, first manipulation mount 105 may itself have many potential shapes and properties to enable releasable attachment to first manipulation instrument 400. Other possible configurations for releasably securing first manipulation mount 105 to first manipulation instrument 400 include, but are not limited to, opposing magnet poles in the mount and instrument, adhesives, a press fit between mount and instrument, threaded couplings, suture loops, a balloon or balloons expanded within a mating cavity, collapsible barbs, etc. For the purposes of the present invention, the important point is that some arrangement be provided for releasably securing the prosthesis holding apparatus (and hence the prosthetic valve) to a manipulation instrument.
  • [0051]
    Still looking now at FIG. 1, first manipulation instrument 400 is shown as having a long axis that extends outside of the heart, with first manipulation instrument 400 being straight along that axis. However, it should also be appreciated that first manipulation instrument 400 may, alternatively, be formed with a curve at one or more location along this length. Furthermore, first manipulation instrument 400 may be constructed so as to allow articulation at the distal end, the proximal end, or both, or at any point therebetween. In addition, first manipulation instrument 400 may be formed either entirely rigid or substantially flexible, along all or part of its length.
  • [0052]
    First manipulation instrument 400 is also shown as having a relatively small dimension perpendicular to its long axis. This configuration allows atriotomy 10 to be reduced in size after the passage of temporary prosthetic assembly 300 into left atrium 5. This perpendicular dimension may be constant or varied along the long axis of first manipulation instrument 400.
  • [0053]
    The specific embodiment of the prosthesis holding apparatus 100 shown in FIG. 1 is presented as an illustrative example only, and is not intended to limit the scope of the present invention. Many other arrangements may be used for releasably gripping prosthetic valve 200 and for providing first manipulation mount 105, as well as providing a second manipulation mount 110 that will be discussed below. In FIG. 1, first manipulation mount 105 and second manipulation mount 110 are shown as spherical additions to struts 115 extending away from prosthetic valve 200. These spheres are intended to fit, respectively, within the deformable gripper 415 of first installation instrument 400 and the deformable gripper 515 of a second installation instrument 500 (discussed below). First manipulation mount 105 and/or second manipulation mount 110 could, alternatively, be indentations within a portion of male or female threaded extensions from, magnetized surfaces of, slots or holes in or through, prosthesis holding apparatus 100, etc. Furthermore, first manipulation mount 105 and/or second manipulation mount 110 could be portions of the struts 115 extending away from prosthetic valve 200, where those portions may be either reduced or enlarged in dimension relative to neighboring portions of the struts. Many other constructions may also be used to form first manipulation mount 105 and second manipulation mount 110. For the purposes of the present invention, the important point is that some arrangement be provided for releasably securing the prosthesis holding apparatus (and hence the prosthetic valve) to manipulation instruments.
  • [0054]
    Still looking now at FIG. 1, it will be appreciated that the native aortic valve has been removed. Removal of the native aortic valve is not a necessary element of the present invention, but may be incorporated into the preferred method. Removal of the native aortic valve may be accomplished either before or after passage of the temporary prosthetic assembly 300 into left atrium 5.
  • [0055]
    When the methods and devices of the present invention are employed during an off-pump valve replacement procedure, it may be beneficial to provide temporary valves and/or filters in the arterial system, downstream of the site of the native aortic valve. Thus, for example, in FIG. 2 there is shown a temporary valve 600 which may be used to support cardiac function during and following removal of the diseased cardiac valve. Temporary valve 600 is shown positioned in aorta 20. Alternatively, temporary valve 600 may be positioned in the aortic arch or the descending aorta. In addition, temporary valve 600 may incorporate a filter therein to mitigate the risks of embolic complications. Alternatively, a separate filter may be employed within the aorta and/or the branch arteries extending therefrom.
  • [0056]
    FIG. 2 shows first manipulation instrument 400 being used to manipulate temporary prosthetic assembly 300 (and hence prosthetic valve 200) into left ventricle 25 through mitral valve 30. After temporary prosthetic assembly 300 has passed into left ventrical 25, the first manipulation instrument 400 will continue to traverse mitral valve 30; however, the reduced perpendicular cross-section of first manipulation instrument 400 will cause only minimal disruption of the function of mitral valve 30.
  • [0057]
    FIG. 3 shows the insertion of a second manipulation instrument 500 through the arterial system and into left ventricle 25. Second manipulation instrument 500 is shown being inserted through an incision 35 on aorta 20. Alternatively, second manipulation instrument 500 could be inserted into a central or peripheral artery and than advanced into left ventricle 25. Aortic incision 35 is small relative to the atriotomy 10 formed in left atrium 5.
  • [0058]
    Bleeding through incision 35 may be readily controlled through a variety of means. These include, but are not limited to, employing a valved or un-valved arterial cannula, a purse-string suture placed around incision 35 and then pulled tight about second manipulation instrument 500, a side-arm graft sewn to aorta 20 that may be constricted about a region of second manipulation instrument 500, the use of a tight fit between a portion of second manipulation instrument 500 and aortic incision 35, etc.
  • [0059]
    Second manipulation instrument 500 is shown in FIG. 3 as being of the same form and function of first manipulation instrument 400. Again, outer cannula 505 fits around inner grasper 510, and the relative motion between grasper 510 and cannula 505 can be used to deform gripper 515 between open and closed positions. Alternatively, second manipulation instrument 500 may have any of the variety of other forms and functions described above with respect to first manipulation instrument 400. Furthermore, second manipulation instrument 500 is preferably of a smaller dimension perpendicular to its long axis than first manipulation instrument 400 so as to reduce the risks posed by arteriotomy 35.
  • [0060]
    FIG. 4 shows second manipulation instrument 500 being secured to the second manipulation mount 110 formed on prosthesis holding apparatus 100. This is done while first manipulation instrument 400 is secured to first manipulation mount 105 formed on prosthesis holding apparatus 100, in order that temporary prosthetic assembly 300 will be under control at all times during the “hand-off” between first manipulation instrument 400 and second manipulation instrument 500.
  • [0061]
    It should be appreciated that the orientation of second manipulation mount 110 is preferably such as to enable the long axis of second manipulation instrument 500 to be substantially perpendicular to the flow area of prosthetic valve 200. This arrangement is particularly helpful when guiding prosthetic valve 200 into its final position within aorta 20 as shown hereafter in FIGS. 6 and 7.
  • [0062]
    The use of two separate manipulation instruments, and the method of passing valve prosthesis 200 from one to the other, avoids the complex manipulations of valve prosthesis 200 that would be required to position valve 200 within aorta 20 using only a single manipulation instrument introduced through the left atrium. In this respect it should be appreciated that such a “single manipulation instrument” technique has been found to be possible, however, and is best facilitated by using a manipulation instrument capable of bending or articulating at or near the site of its attachment to valve holding apparatus 100. In this respect it has been found that it can be particularly advantageous to provide a manipulation instrument capable of bending or articulating within about 4 cm or so of the point of attachment to valve holding apparatus 100. It has also been found that it can be particularly advantageous for such an articulating instrument to be able to deflect its distal tip by an angle of between about 90 to 180 degrees from the long axis of the first manipulation instrument 400 shown in FIG. 4.
  • [0063]
    The angular offset of first manipulation mount 105 and second manipulation mount 110 is preferably set to facilitate passage of temporary prosthetic assembly 300 from left atrium 5 to aorta 20 using two substantially straight manipulation instruments, e.g., first manipulation instrument 400 and second manipulation instrument 500. This angle is preferably approximately 45 degrees. However, this angle may also be varied so as to optimize passage of different valve designs or other prostheses using curved, straight or articulating manipulation instruments from various access sites into the left atrium and arterial system. This angle may be fixed or variable on a given prosthesis holding apparatus 100.
  • [0064]
    Once second manipulation instrument 500 is safely secured to second manipulation mount 110, first manipulation instrument 400 may be released from first manipulation mount 105 and removed from left ventricle 5, as shown in FIG. 5. Alternatively, first manipulation instrument 400 may remain secured to prosthesis holding apparatus 100 or prosthetic valve 200 by a flexible tether so as to facilitate re-attachment of first manipulation instrument 400 to valve holding apparatus 100 if necessary.
  • [0065]
    FIG. 6 shows temporary prosthesis assembly 300 being positioned by second manipulation instrument 500 at a preferred fixation site. This fixation site is preferably upstream of or proximal to the coronary arteries, although this position is not a restrictive requirement of the present invention.
  • [0066]
    FIG. 7 shows valve prosthesis 200 secured to the walls of aorta 30 and removal of second manipulation instrument 500 and prosthesis holding apparatus 100. In this respect it should be appreciated that prosthesis holding apparatus 100 is preferably wholly or partially flexible, or otherwise collapsible, so as to allow the prosthesis holding apparatus 100 to be collapsed radially and then withdrawn through arteriotomy 35 after prosthesis holding apparatus 100 has been released from prosthetic valve 200. Alternatively, prosthesis holding apparatus 100 may be removed from the vascular system, either partially or entirely, through atriotomy 10 by first manipulation instrument 400, by a tether leading therefrom, or a separate instrument. Of course, in the situation where prosthesis holding apparatus 100 is to be removed via atriotomy 10, the prosthesis holding apparatus 100 should be appropriately mounted to prosthetic valve 200, i.e., prosthesis holding apparatus 100 should be positioned on the atriotomy side of the valve.
  • [0067]
    In FIG. 7, valve prosthesis 200 is shown secured to aorta 30 using barbs or staples 700. Barbs or staples 700 may be a component of, and/or deployed from, prosthesis holding apparatus 100, and/or valve prosthesis 200, and/or a separate fixation device. Alternatively, barbs or staples 700 may be deployed by a separate instrument inserted through the outer surface of aorta 30, from a remote site in the arterial system, through atriotomy 10 or through some other incision into a cardiac chamber or great vessel.
  • [0068]
    Looking next at FIGS. 8-10, there is shown one preferred configuration for prosthesis holding apparatus 100. More particularly, prosthesis holding apparatus 100 comprises a base 120 having a longitudinal opening 123 (FIG. 9) therein for slidably receiving a rod 125 therethrough. Base 120 also comprises a plurality of side slots 130. Each side slot 130 has a strut 115 pivotally connected thereto. Slots 130 are constructed so that each strut 115 can pivot freely between (i) the position shown in FIGS. 8 and 9, and (ii) the position shown in FIG. 10. A body 135 is mounted on rod 125. A plurality of wire fingers 140 are secured to body 135. Wire fingers 140 extend through holes 145 formed in base 120 and extend around the cuff 205 of prosthetic valve 200. Second manipulation mount 110 is secured to the proximal end of rod 125. First manipulation mount 105 is secured to one of the struts 115. Alternatively, as noted above, first manipulation mount 105 may be formed by a strut 115 itself, provided that first manipulation instrument 400 is appropriately adapted to engage the strut 15 directly.
  • [0069]
    In use, prosthesis holding apparatus 100 is fit about valve prosthesis 200 so that wire fingers 140 hold valve cuff 205 to struts 115. Prosthesis holding apparatus 100 is then engaged by first manipulation instrument 400, using first manipulation mount 105, and moved into and through right atrium 5, through mitral valve 30 and into left ventricle 25. Then second manipulation tool 500, comprising outer cannula 505 and inner grasper 510 having the deformable gripper 515, engages second manipulation mount 110. The distal tip 520 of outer cannula 505 is placed against edge 150 of base 120 and gripper 515 is drawn proximally within outer cannula 505 until deformable gripper 515 engages shoulder 525, whereupon prosthesis holding apparatus 100 (and hence prosthetic valve 200) will be mounted to second manipulation tool 500. Second manipulation tool 500 is then used to maneuver temporary prosthetic assembly 300 into position, whereupon the valve's cuff 205 is secured to the side wall of the aorta, e.g., with barbs, staples, suture, etc. Then prosthesis holding apparatus 100 is detached from prosthetic valve 200 by pulling inner grasper 510 proximally relative to outer cannula 505 so that wire fingers 140 are pulled past valve cuff 205 (FIG. 9), whereby to free prosthesis holding apparatus 100 from the prosthetic valve 200. Then second manipulation instrument 500 is withdrawn out aorta 20 and arteriotomy 35, with struts 115 folding inwardly (FIG. 10) so as to pass through the arteriotomy. Struts 115 can be adapted to fold inwardly through engagement with the walls of the arteriotomy 35 or, alternatively, additional means (such as springs, cams, etc.) can be provided to fold struts 115 inwardly.
  • [0070]
    In practice, it has been found that it can sometimes be difficult to locate second manipulation mount 110 with second manipulation instrument 500 so as to “hand off' temporary prosthesis assembly 300 from first manipulation instrument 400 to second manipulation instrument 500. This can be particularly true where the procedure is to be conducted “off-pump”, i.e., without stopping the heart. To this end, and looking now at FIG. 11, there is shown a guide 800 for guiding second manipulation instrument 500 relative to first manipulation instrument 400 such that second manipulation instrument 500 will be aimed directly at second manipulation mount 110 when first manipulation mount 105 is secured to first manipulation instrument 400. More particularly, guide 800 comprises a first passageway 805 for slidably receiving first manipulation instrument 400, and a second passageway 810 for slidably receiving second manipulation instrument 500. Passageways 805 and 810 are oriented so that second manipulation instrument 500 will be aimed directly at second manipulation mount 110 when temporary prosthesis assembly 300 is held by first manipulation instrument 400 engaging first manipulation mount 105.
  • [0071]
    In accordance with the present invention, it is also possible to enter the left atrium other than through an exterior wall of the left atrium. Thus, for example, it is possible to introduce the prosthetic valve through an opening in an exterior wall of the right atrium, pass the prosthetic valve through an incision in the interatrial septum and across to the left atrium, and then advance the prosthetic valve to its implantation site via the mitral valve and the left ventricle.
  • [0072]
    As noted above, the manipulation instrument(s) do not need to take the form of the installation instrument 400 or 500. It is also possible to deliver the prosthetic valve to its implant site using a guidewire and a pusher tool riding on the guidewire.
  • [0073]
    Thus, for example, in an alternative preferred embodiment, a wire, a catheter, a tube or any other filament can be placed from the left atrium, through the ventricle and into the arterial system, over (or through) which a prosthesis or device can be advanced (pushed or pulled). As an example, a catheter with a balloon can be placed through an incision in the left atrial wall. The balloon can be inflated and this catheter can then be “floated” along the flow of blood across the mitral valve, into the left ventricle, and out into the arterial system. At that point the catheter can be grasped by an instrument placed through a small incision in the aorta or passed into the aorta by means of a remote vessel such as the femoral artery. At this point, the prosthesis or device can be mounted onto the catheter and either be pushed (or pulled) over the catheter into position. This procedure can be similarly performed by the use of a wire or other filament structure. Also, a tube could be employed, with the prosthesis or device being advanced within the tube.

Claims (34)

1. A method for replacing native valve function of a diseased aortic valve in a patient, comprising:
(a) receiving an artificial heart valve assembly mounted about a first mounting position on a catheter system;
(b) guiding the artificial heart valve assembly through the vasculature of the patient;
(c) while the catheter system having the artificial heart valve assembly mounted thereto is in the patient's vasculature, mounting the artificial heart valve assembly about a second mounting position on the catheter system;
(d) delivering the artificial heart valve assembly to the region of the diseased aortic valve;
(e) expanding the artificial heart valve assembly in the region of the diseased aortic valve; and
(f) withdrawing the catheter system from the patient's vasculature.
2. The method of claim 1, wherein the artificial heart valve assembly is self-expandable.
3. The method of claim 1, wherein the artificial heart valve assembly is balloon expandable.
4. The method of claim 1, wherein the artificial heart valve assembly is delivered to and expanded in the native aortic valve annulus.
5. The method of claim 4, wherein the native aortic valve is excised before the artificial heart valve assembly is expanded in the native aortic valve annulus.
6. The method of claim 1, wherein said expanding the artificial heart valve assembly in the region of the diseased aortic valve occurs while the patient's heart is beating.
7. The method of claim 1, wherein the artificial heart valve assembly is a stented artificial heart valve assembly.
8. The method of claim 1, wherein the artificial heart valve assembly comprises a biological valve.
9. The method of claim 1, wherein the artificial heart valve assembly mounted about the first mounting position is press fit or friction fit about the first mounting position.
10. The method of claim 1, wherein said mounting the artificial heart valve assembly about the second mounting position includes press fitting or friction fitting the artificial heart valve assembly about the second mounting position.
11. The method of claim 1, wherein said guiding the catheter system through the vasculature of the patient includes guiding the catheter system through a peripheral artery of the patient.
12. A method for replacing native valve function of a diseased aortic valve in a patient, comprising:
(a) guiding a catheter system having a balloon through the vasculature of the patient;
(b) guiding an artificial heart valve assembly through the vasculature of the patient;
(c) while the catheter system is in the patient's vasculature, positioning the artificial heart valve assembly about the balloon of the catheter system;
(d) delivering the artificial heart valve assembly to the region of the diseased aortic valve;
(e) expanding the artificial heart valve assembly in the region of the diseased aortic valve; and
(f) withdrawing the catheter system from the patient's vasculature.
13. The method of claim 12, wherein the artificial heart valve assembly was not previously coupled to the catheter system prior to said positioning.
14. The method of claim 12, wherein the artificial heart valve assembly is self-expandable.
15. The method of claim 12, wherein the artificial heart valve assembly is balloon expandable.
16. The method of claim 12, wherein the artificial heart valve assembly is delivered to and expanded in the native aortic valve annulus.
17. The method of claim 16, wherein the native aortic valve is excised before the artificial heart valve assembly is expanded in the native aortic valve annulus.
18. The method of claim 12, wherein said expanding the artificial heart valve assembly the region of the diseased aortic valve occurs while the patient's heart is beating.
19. The method of claim 12, wherein the artificial heart valve assembly is a stented artificial heart valve assembly.
20. The method of claim 12, wherein the artificial heart valve assembly comprises a biological valve.
21. The method of claim 12, wherein said guiding the catheter system through the vasculature of the patient includes guiding the catheter system through a peripheral artery of the patient.
22. The method of claim 12, wherein said guiding the artificial heart valve assembly through the vasculature of the patient includes guiding the artificial heart valve assembly through a peripheral artery of the patient.
23. A system for replacing native valve function of a diseased aortic valve in a patient, comprising:
(a) an artificial heart valve assembly;
(b) a first mount capable of engaging said artificial heart valve assembly while said artificial heart valve assembly is advanced through the patient's vasculature;
(c) a second mount capable of engaging said artificial heart valve assembly while said artificial heart valve assembly is proximate to the region of the diseased aortic valve;
(d) a catheter system capable of being manipulated a first time to transfer said artificial heart valve assembly from said first mount to said second mount, and capable of being manipulated a second time to expand said artificial heart valve assembly into the region of the diseased aortic valve.
24. The system of claim 23, wherein said first mount is not coupled to said catheter system.
25. The system of claim 23, wherein said artificial heart valve assembly is self-expandable.
26. The system of claim 23, wherein said artificial heart valve assembly is balloon expandable.
27. The system of claim 23, wherein said second mount is a balloon.
28. The system of claim 23, wherein the artificial heart valve assembly is expanded into the native aortic valve annulus.
29. The system of claim 28, wherein the native aortic valve has been excised.
30. The system of claim 23, wherein said catheter system is capable of being manipulated to transfer and expand said artificial heart valve assembly while the patient's heart is beating.
31. The system of claim 23, wherein said artificial heart valve assembly is a stented artificial heart valve assembly.
32. The system of claim 23, wherein said artificial heart valve assembly comprises a biological valve.
33. The system of claim 23, wherein said first mount is capable of engaging said artificial heart valve assembly via a press fitting or a friction fitting.
34. The system of claim 23, wherein said first mount is capable of engaging said artificial heart valve assembly while said artificial heart valve assembly is advanced through a peripheral artery of the patient.
US12776136 2000-06-30 2010-05-07 Method For Replacing Native Valve Function Of A Diseased Aortic Valve Abandoned US20100217384A1 (en)

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US09896259 US6769434B2 (en) 2000-06-30 2001-06-29 Method and apparatus for performing a procedure on a cardiac valve
US10895272 US20050055088A1 (en) 2000-06-30 2004-07-20 Method and apparatus for performing a procedure on a cardiac valve
US12776136 US20100217384A1 (en) 2000-06-30 2010-05-07 Method For Replacing Native Valve Function Of A Diseased Aortic Valve

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US13012466 US20110118830A1 (en) 2000-06-30 2011-01-24 System For Replacing Native Valve Function Of A Diseased Aortic Valve

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US12776136 Abandoned US20100217384A1 (en) 2000-06-30 2010-05-07 Method For Replacing Native Valve Function Of A Diseased Aortic Valve
US13012466 Abandoned US20110118830A1 (en) 2000-06-30 2011-01-24 System For Replacing Native Valve Function Of A Diseased Aortic Valve

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8070801B2 (en) 2001-06-29 2011-12-06 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US20130105675A1 (en) * 2011-10-28 2013-05-02 Mitutoyo Corporation Displacement detecting device, displacement detecting method, and computer-readable medium
US8623077B2 (en) 2001-06-29 2014-01-07 Medtronic, Inc. Apparatus for replacing a cardiac valve
US9717831B2 (en) 2014-12-19 2017-08-01 Heartware, Inc. Guidewire system and method of pump installation using same

Families Citing this family (284)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0850607A1 (en) * 1996-12-31 1998-07-01 Cordis Corporation Valve prosthesis for implantation in body channels
US6050936A (en) 1997-01-02 2000-04-18 Myocor, Inc. Heart wall tension reduction apparatus
US7883539B2 (en) 1997-01-02 2011-02-08 Edwards Lifesciences Llc Heart wall tension reduction apparatus and method
FR2768324B1 (en) 1997-09-12 1999-12-10 Jacques Seguin A surgical instrument for percutaneously, fixing one to the other two zones of soft tissue, usually spaced apart
US6332893B1 (en) * 1997-12-17 2001-12-25 Myocor, Inc. Valve to myocardium tension members device and method
US6260552B1 (en) 1998-07-29 2001-07-17 Myocor, Inc. Transventricular implant tools and devices
US6896690B1 (en) 2000-01-27 2005-05-24 Viacor, Inc. Cardiac valve procedure methods and devices
US7749245B2 (en) 2000-01-27 2010-07-06 Medtronic, Inc. Cardiac valve procedure methods and devices
US8216256B2 (en) * 1999-04-09 2012-07-10 Evalve, Inc. Detachment mechanism for implantable fixation devices
US20040044350A1 (en) 1999-04-09 2004-03-04 Evalve, Inc. Steerable access sheath and methods of use
WO2000060995A9 (en) 1999-04-09 2002-06-13 Evalve Inc Methods and apparatus for cardiac valve repair
US7811296B2 (en) 1999-04-09 2010-10-12 Evalve, Inc. Fixation devices for variation in engagement of tissue
US7563267B2 (en) 1999-04-09 2009-07-21 Evalve, Inc. Fixation device and methods for engaging tissue
US6752813B2 (en) 1999-04-09 2004-06-22 Evalve, Inc. Methods and devices for capturing and fixing leaflets in valve repair
US6210432B1 (en) 1999-06-29 2001-04-03 Jan Otto Solem Device and method for treatment of mitral insufficiency
US7192442B2 (en) 1999-06-30 2007-03-20 Edwards Lifesciences Ag Method and device for treatment of mitral insufficiency
US7201771B2 (en) 2001-12-27 2007-04-10 Arbor Surgical Technologies, Inc. Bioprosthetic heart valve
US8016877B2 (en) 1999-11-17 2011-09-13 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US8579966B2 (en) 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US7018406B2 (en) 1999-11-17 2006-03-28 Corevalve Sa Prosthetic valve for transluminal delivery
US8241274B2 (en) 2000-01-19 2012-08-14 Medtronic, Inc. Method for guiding a medical device
US6402781B1 (en) 2000-01-31 2002-06-11 Mitralife Percutaneous mitral annuloplasty and cardiac reinforcement
WO2002005888A1 (en) 2000-06-30 2002-01-24 Viacor Incorporated Intravascular filter with debris entrapment mechanism
US8771302B2 (en) 2001-06-29 2014-07-08 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
WO2002019951A1 (en) 2000-09-07 2002-03-14 Viacor, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US7097659B2 (en) 2001-09-07 2006-08-29 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US7510572B2 (en) * 2000-09-12 2009-03-31 Shlomo Gabbay Implantation system for delivery of a heart valve prosthesis
US6723038B1 (en) 2000-10-06 2004-04-20 Myocor, Inc. Methods and devices for improving mitral valve function
US6602286B1 (en) 2000-10-26 2003-08-05 Ernst Peter Strecker Implantable valve system
US8202315B2 (en) 2001-04-24 2012-06-19 Mitralign, Inc. Catheter-based annuloplasty using ventricularly positioned catheter
US6800090B2 (en) * 2001-05-14 2004-10-05 Cardiac Dimensions, Inc. Mitral valve therapy device, system and method
US6676702B2 (en) * 2001-05-14 2004-01-13 Cardiac Dimensions, Inc. Mitral valve therapy assembly and method
FR2826863B1 (en) 2001-07-04 2003-09-26 Jacques Seguin An assembly for the introduction of a prosthetic valve in a body conduit
FR2828091B1 (en) 2001-07-31 2003-11-21 Seguin Jacques An assembly for the introduction of a prosthetic valve in a body conduit
US6893460B2 (en) * 2001-10-11 2005-05-17 Percutaneous Valve Technologies Inc. Implantable prosthetic valve
US6949122B2 (en) * 2001-11-01 2005-09-27 Cardiac Dimensions, Inc. Focused compression mitral valve device and method
US7635387B2 (en) * 2001-11-01 2009-12-22 Cardiac Dimensions, Inc. Adjustable height focal tissue deflector
US6908478B2 (en) * 2001-12-05 2005-06-21 Cardiac Dimensions, Inc. Anchor and pull mitral valve device and method
US7179282B2 (en) * 2001-12-05 2007-02-20 Cardiac Dimensions, Inc. Device and method for modifying the shape of a body organ
EP2181668A1 (en) 2001-12-28 2010-05-05 Edwards Lifesciences AG Device for treating mitral annulus dilatation comprising a balloon catheter and a stent
US8506624B2 (en) 2002-01-09 2013-08-13 Edwards Lifesciences, Llc Devices and methods for heart valve treatment
US6764510B2 (en) 2002-01-09 2004-07-20 Myocor, Inc. Devices and methods for heart valve treatment
US6976995B2 (en) * 2002-01-30 2005-12-20 Cardiac Dimensions, Inc. Fixed length anchor and pull mitral valve device and method
US7311729B2 (en) 2002-01-30 2007-12-25 Cardiac Dimensions, Inc. Device and method for modifying the shape of a body organ
US6960229B2 (en) 2002-01-30 2005-11-01 Cardiac Dimensions, Inc. Device and method for modifying the shape of a body organ
JP4926980B2 (en) * 2005-01-20 2012-05-09 カーディアック ディメンションズ インコーポレイテッド Organization shaping device
US20050209690A1 (en) * 2002-01-30 2005-09-22 Mathis Mark L Body lumen shaping device with cardiac leads
US7048754B2 (en) 2002-03-01 2006-05-23 Evalve, Inc. Suture fasteners and methods of use
US7004958B2 (en) * 2002-03-06 2006-02-28 Cardiac Dimensions, Inc. Transvenous staples, assembly and method for mitral valve repair
US6797001B2 (en) 2002-03-11 2004-09-28 Cardiac Dimensions, Inc. Device, assembly and method for mitral valve repair
US7007698B2 (en) 2002-04-03 2006-03-07 Boston Scientific Corporation Body lumen closure
US6752828B2 (en) 2002-04-03 2004-06-22 Scimed Life Systems, Inc. Artificial valve
US8721713B2 (en) 2002-04-23 2014-05-13 Medtronic, Inc. System for implanting a replacement valve
DE60325356D1 (en) * 2002-05-08 2009-01-29 Cardiac Dimensions Inc Means for changing the shape of a mitral valve
US6824562B2 (en) * 2002-05-08 2004-11-30 Cardiac Dimensions, Inc. Body lumen device anchor, device and assembly
US7578843B2 (en) 2002-07-16 2009-08-25 Medtronic, Inc. Heart valve prosthesis
US7959674B2 (en) 2002-07-16 2011-06-14 Medtronic, Inc. Suture locking assembly and method of use
EP1592367B1 (en) 2002-08-28 2016-04-13 HLT, Inc. Method and device for treating diseased valve
US7087064B1 (en) * 2002-10-15 2006-08-08 Advanced Cardiovascular Systems, Inc. Apparatuses and methods for heart valve repair
US8979923B2 (en) * 2002-10-21 2015-03-17 Mitralign, Inc. Tissue fastening systems and methods utilizing magnetic guidance
CA2500512A1 (en) 2002-10-21 2004-05-06 Mitralign Incorporated Method and apparatus for performing catheter-based annuloplasty using local plications
US8864822B2 (en) 2003-12-23 2014-10-21 Mitralign, Inc. Devices and methods for introducing elements into tissue
US7416557B2 (en) 2002-10-24 2008-08-26 Boston Scientific Scimed, Inc. Venous valve apparatus and method
US7112219B2 (en) 2002-11-12 2006-09-26 Myocor, Inc. Devices and methods for heart valve treatment
US7404824B1 (en) * 2002-11-15 2008-07-29 Advanced Cardiovascular Systems, Inc. Valve aptation assist device
US6945978B1 (en) 2002-11-15 2005-09-20 Advanced Cardiovascular Systems, Inc. Heart valve catheter
WO2004045378A3 (en) * 2002-11-15 2005-05-12 Robert J Lederman Method and device for catheter-based repair of cardiac valves
US8187324B2 (en) 2002-11-15 2012-05-29 Advanced Cardiovascular Systems, Inc. Telescoping apparatus for delivering and adjusting a medical device in a vessel
US7485143B2 (en) 2002-11-15 2009-02-03 Abbott Cardiovascular Systems Inc. Apparatuses and methods for heart valve repair
US7335213B1 (en) 2002-11-15 2008-02-26 Abbott Cardiovascular Systems Inc. Apparatus and methods for heart valve repair
US7316708B2 (en) * 2002-12-05 2008-01-08 Cardiac Dimensions, Inc. Medical device delivery system
US7837729B2 (en) 2002-12-05 2010-11-23 Cardiac Dimensions, Inc. Percutaneous mitral valve annuloplasty delivery system
US8551162B2 (en) 2002-12-20 2013-10-08 Medtronic, Inc. Biologically implantable prosthesis
US6793673B2 (en) 2002-12-26 2004-09-21 Cardiac Dimensions, Inc. System and method to effect mitral valve annulus of a heart
US6945957B2 (en) 2002-12-30 2005-09-20 Scimed Life Systems, Inc. Valve treatment catheter and methods
US7314485B2 (en) * 2003-02-03 2008-01-01 Cardiac Dimensions, Inc. Mitral valve device using conditioned shape memory alloy
US20040158321A1 (en) * 2003-02-12 2004-08-12 Cardiac Dimensions, Inc. Method of implanting a mitral valve therapy device
WO2004082538A2 (en) * 2003-03-18 2004-09-30 St. Jude Medical, Inc. Body tissue remodeling apparatus
US20040220654A1 (en) * 2003-05-02 2004-11-04 Cardiac Dimensions, Inc. Device and method for modifying the shape of a body organ
US20060161169A1 (en) * 2003-05-02 2006-07-20 Cardiac Dimensions, Inc., A Delaware Corporation Device and method for modifying the shape of a body organ
US7351259B2 (en) * 2003-06-05 2008-04-01 Cardiac Dimensions, Inc. Device, system and method to affect the mitral valve annulus of a heart
US7887582B2 (en) 2003-06-05 2011-02-15 Cardiac Dimensions, Inc. Device and method for modifying the shape of a body organ
CA2533020A1 (en) 2003-07-18 2005-03-03 Ev3 Santa Rosa, Inc. Remotely activated mitral annuloplasty system and methods
US8021421B2 (en) 2003-08-22 2011-09-20 Medtronic, Inc. Prosthesis heart valve fixturing device
CN101365392B (en) * 2005-11-17 2011-02-02 K·R·秦 System and method for implanting spinal stabilization devices
US7998112B2 (en) 2003-09-30 2011-08-16 Abbott Cardiovascular Systems Inc. Deflectable catheter assembly and method of making same
US9579194B2 (en) 2003-10-06 2017-02-28 Medtronic ATS Medical, Inc. Anchoring structure with concave landing zone
US7556647B2 (en) 2003-10-08 2009-07-07 Arbor Surgical Technologies, Inc. Attachment device and methods of using the same
US7837728B2 (en) 2003-12-19 2010-11-23 Cardiac Dimensions, Inc. Reduced length tissue shaping device
US20050137450A1 (en) * 2003-12-19 2005-06-23 Cardiac Dimensions, Inc., A Washington Corporation Tapered connector for tissue shaping device
US9526616B2 (en) * 2003-12-19 2016-12-27 Cardiac Dimensions Pty. Ltd. Mitral valve annuloplasty device with twisted anchor
US8128681B2 (en) 2003-12-19 2012-03-06 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7794496B2 (en) 2003-12-19 2010-09-14 Cardiac Dimensions, Inc. Tissue shaping device with integral connector and crimp
US7854761B2 (en) 2003-12-19 2010-12-21 Boston Scientific Scimed, Inc. Methods for venous valve replacement with a catheter
US20050137449A1 (en) * 2003-12-19 2005-06-23 Cardiac Dimensions, Inc. Tissue shaping device with self-expanding anchors
US7381219B2 (en) 2003-12-23 2008-06-03 Sadra Medical, Inc. Low profile heart valve and delivery system
EP2529696B1 (en) 2003-12-23 2014-01-29 Sadra Medical, Inc. Repositionable heart valve
US7959666B2 (en) 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US20050137694A1 (en) 2003-12-23 2005-06-23 Haug Ulrich R. Methods and apparatus for endovascularly replacing a patient's heart valve
US8052749B2 (en) 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US7329279B2 (en) 2003-12-23 2008-02-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US7445631B2 (en) 2003-12-23 2008-11-04 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US20080228266A1 (en) 2007-03-13 2008-09-18 Mitralign, Inc. Plication assistance devices and methods
US7166127B2 (en) * 2003-12-23 2007-01-23 Mitralign, Inc. Tissue fastening systems and methods utilizing magnetic guidance
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US20090132035A1 (en) * 2004-02-27 2009-05-21 Roth Alex T Prosthetic Heart Valves, Support Structures and Systems and Methods for Implanting the Same
US20070073387A1 (en) * 2004-02-27 2007-03-29 Forster David C Prosthetic Heart Valves, Support Structures And Systems And Methods For Implanting The Same
CA2557657C (en) * 2004-02-27 2013-06-18 Aortx, Inc. Prosthetic heart valve delivery systems and methods
US8109996B2 (en) 2004-03-03 2012-02-07 Sorin Biomedica Cardio, S.R.L. Minimally-invasive cardiac-valve prosthesis
US7993397B2 (en) 2004-04-05 2011-08-09 Edwards Lifesciences Ag Remotely adjustable coronary sinus implant
US20050240200A1 (en) * 2004-04-23 2005-10-27 Bjarne Bergheim Method and system for cardiac valve delivery
WO2005102015A3 (en) 2004-04-23 2007-04-19 3F Therapeutics Inc Implantable prosthetic valve
US7641686B2 (en) 2004-04-23 2010-01-05 Direct Flow Medical, Inc. Percutaneous heart valve with stentless support
US8012201B2 (en) 2004-05-05 2011-09-06 Direct Flow Medical, Inc. Translumenally implantable heart valve with multiple chamber formed in place support
EP1750592B1 (en) 2004-05-14 2016-12-28 Evalve, Inc. Locking mechanisms for fixation devices
US7780725B2 (en) 2004-06-16 2010-08-24 Sadra Medical, Inc. Everting heart valve
US7276078B2 (en) 2004-06-30 2007-10-02 Edwards Lifesciences Pvt Paravalvular leak detection, sealing, and prevention
US7566343B2 (en) 2004-09-02 2009-07-28 Boston Scientific Scimed, Inc. Cardiac valve, system, and method
US20060052867A1 (en) 2004-09-07 2006-03-09 Medtronic, Inc Replacement prosthetic heart valve, system and method of implant
US8052592B2 (en) 2005-09-27 2011-11-08 Evalve, Inc. Methods and devices for tissue grasping and assessment
US20060106415A1 (en) * 2004-11-12 2006-05-18 Shlomo Gabbay Apparatus to facilitate implantation
US20060167468A1 (en) * 2004-11-12 2006-07-27 Shlomo Gabbay Implantation system and method for loading an implanter with a prosthesis
US8562672B2 (en) 2004-11-19 2013-10-22 Medtronic, Inc. Apparatus for treatment of cardiac valves and method of its manufacture
US7211110B2 (en) 2004-12-09 2007-05-01 Edwards Lifesciences Corporation Diagnostic kit to assist with heart valve annulus adjustment
US7981152B1 (en) 2004-12-10 2011-07-19 Advanced Cardiovascular Systems, Inc. Vascular delivery system for accessing and delivering devices into coronary sinus and other vascular sites
US7854755B2 (en) 2005-02-01 2010-12-21 Boston Scientific Scimed, Inc. Vascular catheter, system, and method
US20060173490A1 (en) 2005-02-01 2006-08-03 Boston Scientific Scimed, Inc. Filter system and method
US7878966B2 (en) 2005-02-04 2011-02-01 Boston Scientific Scimed, Inc. Ventricular assist and support device
US7780722B2 (en) 2005-02-07 2010-08-24 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
US7670368B2 (en) 2005-02-07 2010-03-02 Boston Scientific Scimed, Inc. Venous valve apparatus, system, and method
EP2319458B1 (en) 2005-02-10 2013-04-24 Sorin Group Italia S.r.l. Cardiac-valve prosthesis
US7867274B2 (en) 2005-02-23 2011-01-11 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US7513909B2 (en) 2005-04-08 2009-04-07 Arbor Surgical Technologies, Inc. Two-piece prosthetic valves with snap-in connection and methods for use
US7722666B2 (en) 2005-04-15 2010-05-25 Boston Scientific Scimed, Inc. Valve apparatus, system and method
US9149602B2 (en) 2005-04-22 2015-10-06 Advanced Cardiovascular Systems, Inc. Dual needle delivery system
US7962208B2 (en) 2005-04-25 2011-06-14 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US7914569B2 (en) 2005-05-13 2011-03-29 Medtronics Corevalve Llc Heart valve prosthesis and methods of manufacture and use
WO2006128193A3 (en) 2005-05-27 2007-11-22 Heart Leaflet Technologies Inc Stentless support structure
WO2006130505A3 (en) 2005-05-27 2007-06-28 Arbor Surgical Technologies Gasket with collar for prosthetic heart valves and methods for using them
CA2610669A1 (en) 2005-06-07 2006-12-14 Direct Flow Medical, Inc. Stentless aortic valve replacement with high radial strength
US8012198B2 (en) 2005-06-10 2011-09-06 Boston Scientific Scimed, Inc. Venous valve, system, and method
US7780723B2 (en) * 2005-06-13 2010-08-24 Edwards Lifesciences Corporation Heart valve delivery system
US8951285B2 (en) * 2005-07-05 2015-02-10 Mitralign, Inc. Tissue anchor, anchoring system and methods of using the same
US9492277B2 (en) 2005-08-30 2016-11-15 Mayo Foundation For Medical Education And Research Soft body tissue remodeling methods and apparatus
US20070067029A1 (en) * 2005-09-16 2007-03-22 Shlomo Gabbay Support apparatus to facilitate implantation of cardiac prosthesis
US7569071B2 (en) 2005-09-21 2009-08-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
EP1945142B1 (en) 2005-09-26 2013-12-25 Medtronic, Inc. Prosthetic cardiac and venous valves
US8167932B2 (en) 2005-10-18 2012-05-01 Edwards Lifesciences Corporation Heart valve delivery system with valve catheter
US8778017B2 (en) 2005-10-26 2014-07-15 Cardiosolutions, Inc. Safety for mitral valve implant
US7785366B2 (en) * 2005-10-26 2010-08-31 Maurer Christopher W Mitral spacer
US8216302B2 (en) 2005-10-26 2012-07-10 Cardiosolutions, Inc. Implant delivery and deployment system and method
US8449606B2 (en) * 2005-10-26 2013-05-28 Cardiosolutions, Inc. Balloon mitral spacer
US8092525B2 (en) 2005-10-26 2012-01-10 Cardiosolutions, Inc. Heart valve implant
US9078781B2 (en) 2006-01-11 2015-07-14 Medtronic, Inc. Sterile cover for compressible stents used in percutaneous device delivery systems
US7799038B2 (en) 2006-01-20 2010-09-21 Boston Scientific Scimed, Inc. Translumenal apparatus, system, and method
US7967857B2 (en) 2006-01-27 2011-06-28 Medtronic, Inc. Gasket with spring collar for prosthetic heart valves and methods for making and using them
EP1988851A2 (en) 2006-02-14 2008-11-12 Sadra Medical, Inc. Systems and methods for delivering a medical implant
US8147541B2 (en) * 2006-02-27 2012-04-03 Aortx, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US8403981B2 (en) * 2006-02-27 2013-03-26 CardiacMC, Inc. Methods and devices for delivery of prosthetic heart valves and other prosthetics
US7431692B2 (en) * 2006-03-09 2008-10-07 Edwards Lifesciences Corporation Apparatus, system, and method for applying and adjusting a tensioning element to a hollow body organ
US8075615B2 (en) 2006-03-28 2011-12-13 Medtronic, Inc. Prosthetic cardiac valve formed from pericardium material and methods of making same
US7740655B2 (en) 2006-04-06 2010-06-22 Medtronic Vascular, Inc. Reinforced surgical conduit for implantation of a stented valve therein
US7503932B2 (en) * 2006-04-11 2009-03-17 Cardiac Dimensions, Inc. Mitral valve annuloplasty device with vena cava anchor
WO2007130881A3 (en) 2006-04-29 2008-01-31 Arbor Surgical Technologies Multiple component prosthetic heart valve assemblies and apparatus and methods for delivering them
WO2007136532A3 (en) * 2006-05-03 2008-03-13 St Jude Medical Soft body tissue remodeling methods and apparatus
US8585594B2 (en) * 2006-05-24 2013-11-19 Phoenix Biomedical, Inc. Methods of assessing inner surfaces of body lumens or organs
WO2007149905A3 (en) * 2006-06-20 2008-11-06 Aortx Inc Prosthetic valve implant site preparation techniques
EP2298243A1 (en) * 2006-06-20 2011-03-23 AorTx, Inc. Prosthetic heart valves, support structures and systems and methods for implanting the same
US8376865B2 (en) 2006-06-20 2013-02-19 Cardiacmd, Inc. Torque shaft and torque shaft drive
US8142492B2 (en) * 2006-06-21 2012-03-27 Aortx, Inc. Prosthetic valve implantation systems
US7931581B2 (en) * 2006-07-06 2011-04-26 Apaxis Medical, Inc. Automated surgical connector
CA2661959A1 (en) * 2006-09-06 2008-03-13 Aortx, Inc. Prosthetic heart valves, systems and methods of implanting
CN102247223B (en) * 2006-09-08 2015-05-06 爱德华兹生命科学公司 Integrated heart valve delivery system
US8834564B2 (en) 2006-09-19 2014-09-16 Medtronic, Inc. Sinus-engaging valve fixation member
US8876895B2 (en) 2006-09-19 2014-11-04 Medtronic Ventor Technologies Ltd. Valve fixation member having engagement arms
US7854849B2 (en) * 2006-10-10 2010-12-21 Multiphase Systems Integration Compact multiphase inline bulk water separation method and system for hydrocarbon production
EP2083901B1 (en) 2006-10-16 2017-12-27 Medtronic Ventor Technologies Ltd. Transapical delivery system with ventriculo-arterial overflow bypass
US8133213B2 (en) 2006-10-19 2012-03-13 Direct Flow Medical, Inc. Catheter guidance through a calcified aortic valve
US7935144B2 (en) 2006-10-19 2011-05-03 Direct Flow Medical, Inc. Profile reduction of valve implant
CA2671754C (en) 2006-12-06 2015-08-18 Medtronic Corevalve Llc System and method for transapical delivery of an annulus anchored self-expanding valve
US8070799B2 (en) 2006-12-19 2011-12-06 Sorin Biomedica Cardio S.R.L. Instrument and method for in situ deployment of cardiac valve prostheses
US20080147181A1 (en) 2006-12-19 2008-06-19 Sorin Biomedica Cardio S.R.L. Device for in situ axial and radial positioning of cardiac valve prostheses
WO2008091493A1 (en) 2007-01-08 2008-07-31 California Institute Of Technology In-situ formation of a valve
US8460369B2 (en) * 2007-01-18 2013-06-11 Valvexchange Inc. Tools for removal and installation of exchangeable cardiovascular valves
ES2441801T3 (en) 2007-02-05 2014-02-06 Boston Scientific Limited Percutaneous valve and delivery system
EP2129332A1 (en) 2007-02-16 2009-12-09 Medtronic, Inc. Replacement prosthetic heart valves and methods of implantation
US8911461B2 (en) 2007-03-13 2014-12-16 Mitralign, Inc. Suture cutter and method of cutting suture
FR2915087A1 (en) 2007-04-20 2008-10-24 Corevalve Inc Implant treatment of a heart valve, particularly a mitral valve implant inculant material and equipment for setting up of this implant.
US20080262603A1 (en) * 2007-04-23 2008-10-23 Sorin Biomedica Cardio Prosthetic heart valve holder
US8480730B2 (en) * 2007-05-14 2013-07-09 Cardiosolutions, Inc. Solid construct mitral spacer
US8006535B2 (en) 2007-07-12 2011-08-30 Sorin Biomedica Cardio S.R.L. Expandable prosthetic valve crimping device
US8663319B2 (en) 2007-07-23 2014-03-04 Hocor Cardiovascular Technologies Llc Methods and apparatus for percutaneous aortic valve replacement
US8663318B2 (en) * 2007-07-23 2014-03-04 Hocor Cardiovascular Technologies Llc Method and apparatus for percutaneous aortic valve replacement
US8828079B2 (en) 2007-07-26 2014-09-09 Boston Scientific Scimed, Inc. Circulatory valve, system and method
US8747458B2 (en) 2007-08-20 2014-06-10 Medtronic Ventor Technologies Ltd. Stent loading tool and method for use thereof
WO2009026272A1 (en) 2007-08-21 2009-02-26 Valvexchange Inc. Method and apparatus for prosthetic valve removal
CA2697364C (en) 2007-08-23 2017-10-17 Direct Flow Medical, Inc. Translumenally implantable heart valve with formed in place support
US8114154B2 (en) * 2007-09-07 2012-02-14 Sorin Biomedica Cardio S.R.L. Fluid-filled delivery system for in situ deployment of cardiac valve prostheses
US8808367B2 (en) 2007-09-07 2014-08-19 Sorin Group Italia S.R.L. Prosthetic valve delivery system including retrograde/antegrade approach
US20110035018A1 (en) * 2007-09-25 2011-02-10 Depuy Products, Inc. Prosthesis with composite component
US8632600B2 (en) 2007-09-25 2014-01-21 Depuy (Ireland) Prosthesis with modular extensions
US9204967B2 (en) 2007-09-28 2015-12-08 Depuy (Ireland) Fixed-bearing knee prosthesis having interchangeable components
US8715359B2 (en) * 2009-10-30 2014-05-06 Depuy (Ireland) Prosthesis for cemented fixation and method for making the prosthesis
US20090138079A1 (en) * 2007-10-10 2009-05-28 Vector Technologies Ltd. Prosthetic heart valve for transfemoral delivery
US9848981B2 (en) 2007-10-12 2017-12-26 Mayo Foundation For Medical Education And Research Expandable valve prosthesis with sealing mechanism
US8597347B2 (en) 2007-11-15 2013-12-03 Cardiosolutions, Inc. Heart regurgitation method and apparatus
US8852270B2 (en) 2007-11-15 2014-10-07 Cardiosolutions, Inc. Implant delivery system and method
US20110066232A1 (en) * 2007-11-15 2011-03-17 Riveron Fernando A Bioprosthetic valve holder and handle with cutting mechanism and method of using same
US7892276B2 (en) 2007-12-21 2011-02-22 Boston Scientific Scimed, Inc. Valve with delayed leaflet deployment
EP2254513B1 (en) 2008-01-24 2015-10-28 Medtronic, Inc. Stents for prosthetic heart valves
CA2714062A1 (en) 2008-01-24 2009-07-30 Medtronic, Inc. Stents for prosthetic heart valves
US8157853B2 (en) 2008-01-24 2012-04-17 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
WO2009094501A1 (en) 2008-01-24 2009-07-30 Medtronic, Inc. Markers for prosthetic heart valves
US9393115B2 (en) 2008-01-24 2016-07-19 Medtronic, Inc. Delivery systems and methods of implantation for prosthetic heart valves
US9149358B2 (en) 2008-01-24 2015-10-06 Medtronic, Inc. Delivery systems for prosthetic heart valves
US20090264989A1 (en) 2008-02-28 2009-10-22 Philipp Bonhoeffer Prosthetic heart valve systems
US8696689B2 (en) * 2008-03-18 2014-04-15 Medtronic Ventor Technologies Ltd. Medical suturing device and method for use thereof
US8313525B2 (en) 2008-03-18 2012-11-20 Medtronic Ventor Technologies, Ltd. Valve suturing and implantation procedures
US8430927B2 (en) 2008-04-08 2013-04-30 Medtronic, Inc. Multiple orifice implantable heart valve and methods of implantation
US8696743B2 (en) 2008-04-23 2014-04-15 Medtronic, Inc. Tissue attachment devices and methods for prosthetic heart valves
US8312825B2 (en) 2008-04-23 2012-11-20 Medtronic, Inc. Methods and apparatuses for assembly of a pericardial prosthetic heart valve
US8840661B2 (en) 2008-05-16 2014-09-23 Sorin Group Italia S.R.L. Atraumatic prosthetic heart valve prosthesis
US9259317B2 (en) * 2008-06-13 2016-02-16 Cardiosolutions, Inc. System and method for implanting a heart implant
US8591460B2 (en) 2008-06-13 2013-11-26 Cardiosolutions, Inc. Steerable catheter and dilator and system and method for implanting a heart implant
US8006594B2 (en) * 2008-08-11 2011-08-30 Cardiac Dimensions, Inc. Catheter cutting tool
CA2736817A1 (en) * 2008-09-12 2010-03-18 Valvexchange Inc. Valve assembly with exchangeable valve member and a tool set for exchanging the valve member
US8998981B2 (en) 2008-09-15 2015-04-07 Medtronic, Inc. Prosthetic heart valve having identifiers for aiding in radiographic positioning
US8721714B2 (en) 2008-09-17 2014-05-13 Medtronic Corevalve Llc Delivery system for deployment of medical devices
US8852225B2 (en) * 2008-09-25 2014-10-07 Medtronic, Inc. Emboli guarding device
ES2627860T3 (en) 2008-10-10 2017-07-31 Boston Scientific Scimed, Inc. to place medical devices medical devices and installation systems
US8137398B2 (en) 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US8986361B2 (en) 2008-10-17 2015-03-24 Medtronic Corevalve, Inc. Delivery system for deployment of medical devices
WO2010048151A1 (en) * 2008-10-20 2010-04-29 Mitralsolutions, Inc. Method of post-operative adjustment for mitral valve implant
US9119715B2 (en) * 2008-10-30 2015-09-01 St. Jude Medical, Inc. Collapsible/expandable prosthetic heart valve delivery system and methods
US8834563B2 (en) 2008-12-23 2014-09-16 Sorin Group Italia S.R.L. Expandable prosthetic valve having anchoring appendages
US8715207B2 (en) * 2009-03-19 2014-05-06 Sorin Group Italia S.R.L. Universal valve annulus sizing device
ES2543460T3 (en) 2009-03-26 2015-08-19 Sorin Group Usa, Inc. Dimensioning annuloplasty devices for minimally invasive interventions
US8496655B2 (en) * 2009-04-06 2013-07-30 Michael J. O'Donnell System and method for resecting a valve
EP2628465A1 (en) 2009-04-27 2013-08-21 Sorin Group Italia S.r.l. Prosthetic vascular conduit
US8353953B2 (en) 2009-05-13 2013-01-15 Sorin Biomedica Cardio, S.R.L. Device for the in situ delivery of heart valves
US8403982B2 (en) 2009-05-13 2013-03-26 Sorin Group Italia S.R.L. Device for the in situ delivery of heart valves
US9168105B2 (en) 2009-05-13 2015-10-27 Sorin Group Italia S.R.L. Device for surgical interventions
US20110172690A1 (en) * 2009-07-14 2011-07-14 Cohn William E Balloon Catheter for Use with a Surgical Coring System
US8808369B2 (en) 2009-10-05 2014-08-19 Mayo Foundation For Medical Education And Research Minimally invasive aortic valve replacement
US8870950B2 (en) 2009-12-08 2014-10-28 Mitral Tech Ltd. Rotation-based anchoring of an implant
US9226826B2 (en) 2010-02-24 2016-01-05 Medtronic, Inc. Transcatheter valve structure and methods for valve delivery
US20110224785A1 (en) * 2010-03-10 2011-09-15 Hacohen Gil Prosthetic mitral valve with tissue anchors
US8652204B2 (en) 2010-04-01 2014-02-18 Medtronic, Inc. Transcatheter valve with torsion spring fixation and related systems and methods
CN103124537B (en) 2010-05-10 2015-08-26 心叶科技公司 Stentless support structure
EP2387972B1 (en) 2010-05-21 2013-12-25 Sorin Group Italia S.r.l. A support device for valve prostheses and corresponding kit
US9132009B2 (en) 2010-07-21 2015-09-15 Mitraltech Ltd. Guide wires with commissural anchors to advance a prosthetic valve
US9763657B2 (en) 2010-07-21 2017-09-19 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US8992604B2 (en) 2010-07-21 2015-03-31 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
EP2486894A1 (en) 2011-02-14 2012-08-15 Sorin Biomedica Cardio S.r.l. Sutureless anchoring device for cardiac valve prostheses
ES2641902T3 (en) 2011-02-14 2017-11-14 Sorin Group Italia S.R.L. Anchoring device for sutureless heart valve prostheses
US9586024B2 (en) * 2011-04-18 2017-03-07 Medtronic Vascular, Inc. Guide catheter with radiopaque filaments for locating an ostium
JP2014527425A (en) 2011-07-12 2014-10-16 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Coupling system for medical equipment
US9668859B2 (en) 2011-08-05 2017-06-06 California Institute Of Technology Percutaneous heart valve delivery systems
US8852272B2 (en) 2011-08-05 2014-10-07 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
EP2842517A1 (en) 2011-12-29 2015-03-04 Sorin Group Italia S.r.l. A kit for implanting prosthetic vascular conduits
US9011515B2 (en) 2012-04-19 2015-04-21 Caisson Interventional, LLC Heart valve assembly systems and methods
US9427315B2 (en) 2012-04-19 2016-08-30 Caisson Interventional, LLC Valve replacement systems and methods
EP2948103A2 (en) 2013-01-24 2015-12-02 Mitraltech Ltd. Ventricularly-anchored prosthetic valves
EP2967945A4 (en) 2013-03-15 2016-11-09 California Inst Of Techn Handle mechanism and functionality for repositioning and retrieval of transcatheter heart valves
US9289297B2 (en) 2013-03-15 2016-03-22 Cardiosolutions, Inc. Mitral valve spacer and system and method for implanting the same
CN105208973A (en) 2013-03-15 2015-12-30 Hlt股份有限公司 Low-profile prosthetic valve structure
US9232998B2 (en) 2013-03-15 2016-01-12 Cardiosolutions Inc. Trans-apical implant systems, implants and methods
US9629718B2 (en) 2013-05-03 2017-04-25 Medtronic, Inc. Valve delivery tool
KR20160041040A (en) 2013-06-14 2016-04-15 카디오솔루션즈, 인코포레이티드 Mitral valve spacer and system and method for implanting the same
US9050188B2 (en) 2013-10-23 2015-06-09 Caisson Interventional, LLC Methods and systems for heart valve therapy
EP2979664A1 (en) 2014-08-01 2016-02-03 Alvimedica Tibbi Ürünler Sanayi Ve Dis Ticaret A.S Aortic valve prosthesis, particularly suitable for transcatheter implantation
US9750605B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
US9750607B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
CN104367351B (en) * 2014-12-03 2017-12-19 李鸿雁 An artificial chordae interventional device
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
USD800908S1 (en) 2016-08-10 2017-10-24 Mitraltech Ltd. Prosthetic valve element

Citations (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642004A (en) * 1970-01-05 1972-02-15 Life Support Equipment Corp Urethral valve
US3795246A (en) * 1973-01-26 1974-03-05 Bard Inc C R Venocclusion device
US3868956A (en) * 1972-06-05 1975-03-04 Ralph J Alfidi Vessel implantable appliance and method of implanting it
US4373216A (en) * 1980-10-27 1983-02-15 Hemex, Inc. Heart valves having edge-guided occluders
US4425908A (en) * 1981-10-22 1984-01-17 Beth Israel Hospital Blood clot filter
US4501030A (en) * 1981-08-17 1985-02-26 American Hospital Supply Corporation Method of leaflet attachment for prosthetic heart valves
US4643732A (en) * 1984-11-17 1987-02-17 Beiersdorf Aktiengesellschaft Heart valve prosthesis
US4647283A (en) * 1982-03-23 1987-03-03 American Hospital Supply Corporation Implantable biological tissue and process for preparation thereof
US4909252A (en) * 1988-05-26 1990-03-20 The Regents Of The Univ. Of California Perfusion balloon catheter
US5002559A (en) * 1989-11-30 1991-03-26 Numed PTCA catheter
US5011469A (en) * 1988-08-29 1991-04-30 Shiley, Inc. Peripheral cardiopulmonary bypass and coronary reperfusion system
US5080668A (en) * 1988-11-29 1992-01-14 Biotronik Mess- und Therapiegerate GmbH & Co. KG Ingenieurburo Berlin Cardiac valve prosthesis
US5192297A (en) * 1991-12-31 1993-03-09 Medtronic, Inc. Apparatus and method for placement and implantation of a stent
US5282847A (en) * 1991-02-28 1994-02-01 Medtronic, Inc. Prosthetic vascular grafts with a pleated structure
US5389106A (en) * 1993-10-29 1995-02-14 Numed, Inc. Impermeable expandable intravascular stent
US5489294A (en) * 1994-02-01 1996-02-06 Medtronic, Inc. Steroid eluting stitch-in chronic cardiac lead
US5489297A (en) * 1992-01-27 1996-02-06 Duran; Carlos M. G. Bioprosthetic heart valve with absorbable stent
US5496346A (en) * 1987-01-06 1996-03-05 Advanced Cardiovascular Systems, Inc. Reinforced balloon dilatation catheter with slitted exchange sleeve and method
US5591195A (en) * 1995-10-30 1997-01-07 Taheri; Syde Apparatus and method for engrafting a blood vessel
US5591185A (en) * 1989-12-14 1997-01-07 Corneal Contouring Development L.L.C. Method and apparatus for reprofiling or smoothing the anterior or stromal cornea by scraping
US5599305A (en) * 1994-10-24 1997-02-04 Cardiovascular Concepts, Inc. Large-diameter introducer sheath having hemostasis valve and removable steering mechanism
US5702368A (en) * 1991-07-16 1997-12-30 Heartport, Inc. System for cardiac procedures
US5713953A (en) * 1991-05-24 1998-02-03 Sorin Biomedica Cardio S.P.A. Cardiac valve prosthesis particularly for replacement of the aortic valve
US5713950A (en) * 1993-11-01 1998-02-03 Cox; James L. Method of replacing heart valves using flexible tubes
US5792179A (en) * 1996-07-16 1998-08-11 Sideris; Eleftherios B. Retrievable cardiac balloon placement
US5855601A (en) * 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same
US5855602A (en) * 1996-09-09 1999-01-05 Shelhigh, Inc. Heart valve prosthesis
US5861028A (en) * 1996-09-09 1999-01-19 Shelhigh Inc Natural tissue heart valve and stent prosthesis and method for making the same
US5957949A (en) * 1997-05-01 1999-09-28 World Medical Manufacturing Corp. Percutaneous placement valve stent
US6022370A (en) * 1996-10-01 2000-02-08 Numed, Inc. Expandable stent
US6029671A (en) * 1991-07-16 2000-02-29 Heartport, Inc. System and methods for performing endovascular procedures
US6174327B1 (en) * 1998-02-27 2001-01-16 Scimed Life Systems, Inc. Stent deployment apparatus and method
US6190397B1 (en) * 1996-09-16 2001-02-20 Origin Medsystems, Inc. Means and method for performing an anastomosis
US6241699B1 (en) * 1998-07-22 2001-06-05 Chase Medical, Inc. Catheter system and method for posterior epicardial revascularization and intracardiac surgery on a beating heart
US6338735B1 (en) * 1991-07-16 2002-01-15 John H. Stevens Methods for removing embolic material in blood flowing through a patient's ascending aorta
US20020010508A1 (en) * 1997-11-25 2002-01-24 Chobotov Michael V. Layered endovascular graft
US6348063B1 (en) * 1999-03-11 2002-02-19 Mindguard Ltd. Implantable stroke treating device
US6398726B1 (en) * 1998-11-20 2002-06-04 Intuitive Surgical, Inc. Stabilizer for robotic beating-heart surgery
US6425916B1 (en) * 1999-02-10 2002-07-30 Michi E. Garrison Methods and devices for implanting cardiac valves
US20020144696A1 (en) * 1998-02-13 2002-10-10 A. Adam Sharkawy Conduits for use in placing a target vessel in fluid communication with a source of blood
US6468265B1 (en) * 1998-11-20 2002-10-22 Intuitive Surgical, Inc. Performing cardiac surgery without cardioplegia
US6503272B2 (en) * 2001-03-21 2003-01-07 Cordis Corporation Stent-based venous valves
US20030014104A1 (en) * 1996-12-31 2003-01-16 Alain Cribier Value prosthesis for implantation in body channels
US6508833B2 (en) * 1998-06-02 2003-01-21 Cook Incorporated Multiple-sided intraluminal medical device
US20030023300A1 (en) * 1999-12-31 2003-01-30 Bailey Steven R. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US20030023303A1 (en) * 1999-11-19 2003-01-30 Palmaz Julio C. Valvular prostheses having metal or pseudometallic construction and methods of manufacture
US20030028247A1 (en) * 2001-01-29 2003-02-06 Cali Douglas S. Method of cutting material for use in implantable medical device
US20030036791A1 (en) * 2001-08-03 2003-02-20 Bonhoeffer Philipp Implant implantation unit and procedure for implanting the unit
US20030036795A1 (en) * 1990-05-18 2003-02-20 Andersen Henning Rud Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis
US20030040736A1 (en) * 1991-07-16 2003-02-27 John H. Stevens Endovacular cardiac venting catheter and method
US20030040792A1 (en) * 2000-09-12 2003-02-27 Shlomo Gabbay Heart valve prosthesis and sutureless implantation of a heart valve prosthesis
US20030040772A1 (en) * 1999-02-01 2003-02-27 Hideki Hyodoh Delivery devices
US6596003B1 (en) * 2000-06-28 2003-07-22 Genzyme Corporation Vascular anastomosis device
US6629534B1 (en) * 1999-04-09 2003-10-07 Evalve, Inc. Methods and apparatus for cardiac valve repair
US6673089B1 (en) * 1999-03-11 2004-01-06 Mindguard Ltd. Implantable stroke treating device
US6673040B1 (en) * 1996-04-16 2004-01-06 Cardeon Corporation System and methods for catheter procedures with circulatory support in high risk patients
US6676698B2 (en) * 2000-06-26 2004-01-13 Rex Medicol, L.P. Vascular device with valve for approximating vessel wall
US6682559B2 (en) * 2000-01-27 2004-01-27 3F Therapeutics, Inc. Prosthetic heart valve
US6682558B2 (en) * 2001-05-10 2004-01-27 3F Therapeutics, Inc. Delivery system for a stentless valve bioprosthesis
US20040019374A1 (en) * 2002-05-10 2004-01-29 Hikmat Hojeibane Frame based unidirectional flow prosthetic implant
US6685739B2 (en) * 1999-10-21 2004-02-03 Scimed Life Systems, Inc. Implantable prosthetic valve
US6689164B1 (en) * 1999-10-12 2004-02-10 Jacques Seguin Annuloplasty device for use in minimally invasive procedure
US6689144B2 (en) * 2002-02-08 2004-02-10 Scimed Life Systems, Inc. Rapid exchange catheter and methods for delivery of vaso-occlusive devices
US6692512B2 (en) * 1998-10-13 2004-02-17 Edwards Lifesciences Corporation Percutaneous filtration catheter for valve repair surgery and methods of use
US6692513B2 (en) * 2000-06-30 2004-02-17 Viacor, Inc. Intravascular filter with debris entrapment mechanism
US20040034411A1 (en) * 2002-08-16 2004-02-19 Quijano Rodolfo C. Percutaneously delivered heart valve and delivery means thereof
US6695878B2 (en) * 2000-06-26 2004-02-24 Rex Medical, L.P. Vascular device for valve leaflet apposition
US20040039436A1 (en) * 2001-10-11 2004-02-26 Benjamin Spenser Implantable prosthetic valve
US6802319B2 (en) * 1993-02-22 2004-10-12 John H. Stevens Minimally-invasive devices and methods for treatment of congestive heart failure
US20050010285A1 (en) * 1999-01-27 2005-01-13 Lambrecht Gregory H. Cardiac valve procedure methods and devices
US20050010287A1 (en) * 2000-09-20 2005-01-13 Ample Medical, Inc. Devices, systems, and methods for supplementing, repairing, or replacing a native heart valve leaflet
US20050015112A1 (en) * 2000-01-27 2005-01-20 Cohn William E. Cardiac valve procedure methods and devices
US6846325B2 (en) * 2000-09-07 2005-01-25 Viacor, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US20050027348A1 (en) * 2003-07-31 2005-02-03 Case Brian C. Prosthetic valve devices and methods of making such devices
US20050033398A1 (en) * 2001-07-31 2005-02-10 Jacques Seguin Assembly for setting a valve prosthesis in a corporeal duct
US20050043790A1 (en) * 2001-07-04 2005-02-24 Jacques Seguin Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body
US20060004469A1 (en) * 2004-06-16 2006-01-05 Justin Sokel Tissue prosthesis processing technology
US20060004439A1 (en) * 2004-06-30 2006-01-05 Benjamin Spenser Device and method for assisting in the implantation of a prosthetic valve
US20060009841A1 (en) * 2003-05-05 2006-01-12 Rex Medical Percutaneous aortic valve
US6986742B2 (en) * 2001-08-21 2006-01-17 Boston Scientific Scimed, Inc. Pressure transducer protection valve
US6989028B2 (en) * 2000-01-31 2006-01-24 Edwards Lifesciences Ag Medical system and method for remodeling an extravascular tissue structure
US6989027B2 (en) * 2003-04-30 2006-01-24 Medtronic Vascular Inc. Percutaneously delivered temporary valve assembly
US6991649B2 (en) * 2003-08-29 2006-01-31 Hans-Hinrich Sievers Artificial heart valve
US20070005129A1 (en) * 2000-02-28 2007-01-04 Christoph Damm Anchoring system for implantable heart valve prostheses
US20070005131A1 (en) * 2005-06-13 2007-01-04 Taylor David M Heart valve delivery system
US7160319B2 (en) * 1999-11-16 2007-01-09 Scimed Life Systems, Inc. Multi-section filamentary endoluminal stent
US20070010878A1 (en) * 2003-11-12 2007-01-11 Medtronic Vascular, Inc. Coronary sinus approach for repair of mitral valve regurgitation
US20070016286A1 (en) * 2003-07-21 2007-01-18 Herrmann Howard C Percutaneous heart valve
US20070027533A1 (en) * 2005-07-28 2007-02-01 Medtronic Vascular, Inc. Cardiac valve annulus restraining device
US20070027518A1 (en) * 2003-04-01 2007-02-01 Case Brian C Percutaneously deployed vascular valves
US7175656B2 (en) * 2003-04-18 2007-02-13 Alexander Khairkhahan Percutaneous transcatheter heart valve replacement
US20070038295A1 (en) * 2005-08-12 2007-02-15 Cook Incorporated Artificial valve prosthesis having a ring frame
US20070043431A1 (en) * 2005-08-19 2007-02-22 Cook Incorporated Prosthetic valve
US20080004696A1 (en) * 2006-06-29 2008-01-03 Valvexchange Inc. Cardiovascular valve assembly with resizable docking station
US7316706B2 (en) * 2003-06-20 2008-01-08 Medtronic Vascular, Inc. Tensioning device, system, and method for treating mitral valve regurgitation
US20080015671A1 (en) * 2004-11-19 2008-01-17 Philipp Bonhoeffer Method And Apparatus For Treatment Of Cardiac Valves
US20080021552A1 (en) * 2001-10-09 2008-01-24 Shlomo Gabbay Apparatus To Facilitate Implantation
US7329278B2 (en) * 1999-11-17 2008-02-12 Corevalve, Inc. Prosthetic valve for transluminal delivery
US7335218B2 (en) * 2002-08-28 2008-02-26 Heart Leaflet Technologies, Inc. Delivery device for leaflet valve
US20080048656A1 (en) * 2006-07-14 2008-02-28 Fengshun Tan Thermal controlling method, magnetic field generator and mri apparatus
US20090005863A1 (en) * 2006-02-16 2009-01-01 Goetz Wolfgang Minimally invasive heart valve replacement
US20090012600A1 (en) * 2005-04-05 2009-01-08 Mikolaj Witold Styrc Kit Which Is Intended to Be Implanted in a Blood Vessel, and Associated Tubular Endoprosthesis
US7481838B2 (en) * 1999-01-26 2009-01-27 Edwards Lifesciences Corporation Flexible heart valve and associated connecting band
US20090048656A1 (en) * 2005-11-09 2009-02-19 Ning Wen Delivery Device for Delivering a Self-Expanding Stent
US20090054976A1 (en) * 2007-08-20 2009-02-26 Yosi Tuval Stent loading tool and method for use thereof
US20100036479A1 (en) * 2008-04-23 2010-02-11 Medtronic, Inc. Stented Heart Valve Devices

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3628535A (en) * 1969-11-12 1971-12-21 Nibot Corp Surgical instrument for implanting a prosthetic heart valve or the like
US5041130A (en) 1989-07-31 1991-08-20 Baxter International Inc. Flexible annuloplasty ring and holder
US6010531A (en) * 1993-02-22 2000-01-04 Heartport, Inc. Less-invasive devices and methods for cardiac valve surgery
US5972030A (en) 1993-02-22 1999-10-26 Heartport, Inc. Less-invasive devices and methods for treatment of cardiac valves
US5480423A (en) * 1993-05-20 1996-01-02 Boston Scientific Corporation Prosthesis delivery
CA2179718A1 (en) * 1993-12-22 1995-06-29 Mogens Bugge Cardiac valve holders
US5476510A (en) * 1994-04-21 1995-12-19 Medtronic, Inc. Holder for heart valve
US5443502A (en) * 1994-06-02 1995-08-22 Carbomedics, Inc. Rotatable heart valve holder
US6019790A (en) * 1995-05-24 2000-02-01 St. Jude Medical, Inc. Heart valve holder having a locking collar
US6214043B1 (en) * 1995-05-24 2001-04-10 St. Jude Medical, Inc. Releasable hanger for heart valve prosthesis low profile holder
US5807405A (en) * 1995-09-11 1998-09-15 St. Jude Medical, Inc. Apparatus for attachment of heart valve holder to heart valve prosthesis
US5989281A (en) * 1995-11-07 1999-11-23 Embol-X, Inc. Cannula with associated filter and methods of use during cardiac surgery
US5716370A (en) * 1996-02-23 1998-02-10 Williamson, Iv; Warren Means for replacing a heart valve in a minimally invasive manner
US5662671A (en) * 1996-07-17 1997-09-02 Embol-X, Inc. Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries
US5972020A (en) * 1997-02-14 1999-10-26 Cardiothoracic Systems, Inc. Surgical instrument for cardiac valve repair on the beating heart
US5910144A (en) * 1998-01-09 1999-06-08 Endovascular Technologies, Inc. Prosthesis gripping system and method
US7569062B1 (en) * 1998-07-15 2009-08-04 St. Jude Medical, Inc. Mitral and tricuspid valve repair
US7563267B2 (en) * 1999-04-09 2009-07-21 Evalve, Inc. Fixation device and methods for engaging tissue
US20070043435A1 (en) * 1999-11-17 2007-02-22 Jacques Seguin Non-cylindrical prosthetic valve system for transluminal delivery
US6893459B1 (en) * 2000-09-20 2005-05-17 Ample Medical, Inc. Heart valve annulus device and method of using same
US7223291B2 (en) * 2001-07-16 2007-05-29 Spinecore, Inc. Intervertebral spacer device having engagement hole pairs for manipulation using a surgical tool
US6673100B2 (en) * 2001-05-25 2004-01-06 Cordis Neurovascular, Inc. Method and device for retrieving embolic coils
DE10136401A1 (en) * 2001-07-26 2003-02-13 Windmoeller & Hoelscher flexographic printing
US7399315B2 (en) * 2003-03-18 2008-07-15 Edwards Lifescience Corporation Minimally-invasive heart valve with cusp positioners
US8012201B2 (en) * 2004-05-05 2011-09-06 Direct Flow Medical, Inc. Translumenally implantable heart valve with multiple chamber formed in place support
JP2008506497A (en) * 2004-07-19 2008-03-06 セント ジュード メディカル インコーポレイテッド Support of heart valves and lid backing system and method
WO2007130881A3 (en) * 2006-04-29 2008-01-31 Arbor Surgical Technologies Multiple component prosthetic heart valve assemblies and apparatus and methods for delivering them

Patent Citations (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642004A (en) * 1970-01-05 1972-02-15 Life Support Equipment Corp Urethral valve
US3868956A (en) * 1972-06-05 1975-03-04 Ralph J Alfidi Vessel implantable appliance and method of implanting it
US3795246A (en) * 1973-01-26 1974-03-05 Bard Inc C R Venocclusion device
US4373216A (en) * 1980-10-27 1983-02-15 Hemex, Inc. Heart valves having edge-guided occluders
US4501030A (en) * 1981-08-17 1985-02-26 American Hospital Supply Corporation Method of leaflet attachment for prosthetic heart valves
US4425908A (en) * 1981-10-22 1984-01-17 Beth Israel Hospital Blood clot filter
US4648881A (en) * 1982-03-23 1987-03-10 American Hospital Supply Corporation Implantable biological tissue and process for preparation thereof
US4647283A (en) * 1982-03-23 1987-03-03 American Hospital Supply Corporation Implantable biological tissue and process for preparation thereof
US4643732A (en) * 1984-11-17 1987-02-17 Beiersdorf Aktiengesellschaft Heart valve prosthesis
US5496346A (en) * 1987-01-06 1996-03-05 Advanced Cardiovascular Systems, Inc. Reinforced balloon dilatation catheter with slitted exchange sleeve and method
US4909252A (en) * 1988-05-26 1990-03-20 The Regents Of The Univ. Of California Perfusion balloon catheter
US5011469A (en) * 1988-08-29 1991-04-30 Shiley, Inc. Peripheral cardiopulmonary bypass and coronary reperfusion system
US5080668A (en) * 1988-11-29 1992-01-14 Biotronik Mess- und Therapiegerate GmbH & Co. KG Ingenieurburo Berlin Cardiac valve prosthesis
US5002559A (en) * 1989-11-30 1991-03-26 Numed PTCA catheter
US5591185A (en) * 1989-12-14 1997-01-07 Corneal Contouring Development L.L.C. Method and apparatus for reprofiling or smoothing the anterior or stromal cornea by scraping
US20030036795A1 (en) * 1990-05-18 2003-02-20 Andersen Henning Rud Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis
US5282847A (en) * 1991-02-28 1994-02-01 Medtronic, Inc. Prosthetic vascular grafts with a pleated structure
US5713953A (en) * 1991-05-24 1998-02-03 Sorin Biomedica Cardio S.P.A. Cardiac valve prosthesis particularly for replacement of the aortic valve
US6029671A (en) * 1991-07-16 2000-02-29 Heartport, Inc. System and methods for performing endovascular procedures
US20030040736A1 (en) * 1991-07-16 2003-02-27 John H. Stevens Endovacular cardiac venting catheter and method
US5702368A (en) * 1991-07-16 1997-12-30 Heartport, Inc. System for cardiac procedures
US6338735B1 (en) * 1991-07-16 2002-01-15 John H. Stevens Methods for removing embolic material in blood flowing through a patient's ascending aorta
US5192297A (en) * 1991-12-31 1993-03-09 Medtronic, Inc. Apparatus and method for placement and implantation of a stent
US5489297A (en) * 1992-01-27 1996-02-06 Duran; Carlos M. G. Bioprosthetic heart valve with absorbable stent
US6802319B2 (en) * 1993-02-22 2004-10-12 John H. Stevens Minimally-invasive devices and methods for treatment of congestive heart failure
US5389106A (en) * 1993-10-29 1995-02-14 Numed, Inc. Impermeable expandable intravascular stent
US6673109B2 (en) * 1993-11-01 2004-01-06 3F Therapeutics, Inc. Replacement atrioventricular heart valve
US5713950A (en) * 1993-11-01 1998-02-03 Cox; James L. Method of replacing heart valves using flexible tubes
US5489294A (en) * 1994-02-01 1996-02-06 Medtronic, Inc. Steroid eluting stitch-in chronic cardiac lead
US5599305A (en) * 1994-10-24 1997-02-04 Cardiovascular Concepts, Inc. Large-diameter introducer sheath having hemostasis valve and removable steering mechanism
US5591195A (en) * 1995-10-30 1997-01-07 Taheri; Syde Apparatus and method for engrafting a blood vessel
US6673040B1 (en) * 1996-04-16 2004-01-06 Cardeon Corporation System and methods for catheter procedures with circulatory support in high risk patients
US5855601A (en) * 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same
US5792179A (en) * 1996-07-16 1998-08-11 Sideris; Eleftherios B. Retrievable cardiac balloon placement
US5861028A (en) * 1996-09-09 1999-01-19 Shelhigh Inc Natural tissue heart valve and stent prosthesis and method for making the same
US5855602A (en) * 1996-09-09 1999-01-05 Shelhigh, Inc. Heart valve prosthesis
US6190397B1 (en) * 1996-09-16 2001-02-20 Origin Medsystems, Inc. Means and method for performing an anastomosis
US6022370A (en) * 1996-10-01 2000-02-08 Numed, Inc. Expandable stent
US20080009940A1 (en) * 1996-12-31 2008-01-10 Alain Cribier Valve prosthesis for implantation in body channels
US20030014104A1 (en) * 1996-12-31 2003-01-16 Alain Cribier Value prosthesis for implantation in body channels
US5957949A (en) * 1997-05-01 1999-09-28 World Medical Manufacturing Corp. Percutaneous placement valve stent
US20020010508A1 (en) * 1997-11-25 2002-01-24 Chobotov Michael V. Layered endovascular graft
US20020144696A1 (en) * 1998-02-13 2002-10-10 A. Adam Sharkawy Conduits for use in placing a target vessel in fluid communication with a source of blood
US6174327B1 (en) * 1998-02-27 2001-01-16 Scimed Life Systems, Inc. Stent deployment apparatus and method
US6508833B2 (en) * 1998-06-02 2003-01-21 Cook Incorporated Multiple-sided intraluminal medical device
US6241699B1 (en) * 1998-07-22 2001-06-05 Chase Medical, Inc. Catheter system and method for posterior epicardial revascularization and intracardiac surgery on a beating heart
US6692512B2 (en) * 1998-10-13 2004-02-17 Edwards Lifesciences Corporation Percutaneous filtration catheter for valve repair surgery and methods of use
US6468265B1 (en) * 1998-11-20 2002-10-22 Intuitive Surgical, Inc. Performing cardiac surgery without cardioplegia
US6398726B1 (en) * 1998-11-20 2002-06-04 Intuitive Surgical, Inc. Stabilizer for robotic beating-heart surgery
US7481838B2 (en) * 1999-01-26 2009-01-27 Edwards Lifesciences Corporation Flexible heart valve and associated connecting band
US7470284B2 (en) * 1999-01-27 2008-12-30 Medtronic, Inc. Cardiac valve procedure methods and devices
US20050010285A1 (en) * 1999-01-27 2005-01-13 Lambrecht Gregory H. Cardiac valve procedure methods and devices
US20030040772A1 (en) * 1999-02-01 2003-02-27 Hideki Hyodoh Delivery devices
US20030040771A1 (en) * 1999-02-01 2003-02-27 Hideki Hyodoh Methods for creating woven devices
US6425916B1 (en) * 1999-02-10 2002-07-30 Michi E. Garrison Methods and devices for implanting cardiac valves
US6673089B1 (en) * 1999-03-11 2004-01-06 Mindguard Ltd. Implantable stroke treating device
US6348063B1 (en) * 1999-03-11 2002-02-19 Mindguard Ltd. Implantable stroke treating device
US6629534B1 (en) * 1999-04-09 2003-10-07 Evalve, Inc. Methods and apparatus for cardiac valve repair
US6689164B1 (en) * 1999-10-12 2004-02-10 Jacques Seguin Annuloplasty device for use in minimally invasive procedure
US6685739B2 (en) * 1999-10-21 2004-02-03 Scimed Life Systems, Inc. Implantable prosthetic valve
US7160319B2 (en) * 1999-11-16 2007-01-09 Scimed Life Systems, Inc. Multi-section filamentary endoluminal stent
US7329278B2 (en) * 1999-11-17 2008-02-12 Corevalve, Inc. Prosthetic valve for transluminal delivery
US20030023303A1 (en) * 1999-11-19 2003-01-30 Palmaz Julio C. Valvular prostheses having metal or pseudometallic construction and methods of manufacture
US20030023300A1 (en) * 1999-12-31 2003-01-30 Bailey Steven R. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US20050015112A1 (en) * 2000-01-27 2005-01-20 Cohn William E. Cardiac valve procedure methods and devices
US6896690B1 (en) * 2000-01-27 2005-05-24 Viacor, Inc. Cardiac valve procedure methods and devices
US6682559B2 (en) * 2000-01-27 2004-01-27 3F Therapeutics, Inc. Prosthetic heart valve
US6989028B2 (en) * 2000-01-31 2006-01-24 Edwards Lifesciences Ag Medical system and method for remodeling an extravascular tissue structure
US20070005129A1 (en) * 2000-02-28 2007-01-04 Christoph Damm Anchoring system for implantable heart valve prostheses
US6695878B2 (en) * 2000-06-26 2004-02-24 Rex Medical, L.P. Vascular device for valve leaflet apposition
US6676698B2 (en) * 2000-06-26 2004-01-13 Rex Medicol, L.P. Vascular device with valve for approximating vessel wall
US6596003B1 (en) * 2000-06-28 2003-07-22 Genzyme Corporation Vascular anastomosis device
US6692513B2 (en) * 2000-06-30 2004-02-17 Viacor, Inc. Intravascular filter with debris entrapment mechanism
US20050010246A1 (en) * 2000-06-30 2005-01-13 Streeter Richard B. Intravascular filter with debris entrapment mechanism
US6846325B2 (en) * 2000-09-07 2005-01-25 Viacor, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US20030040792A1 (en) * 2000-09-12 2003-02-27 Shlomo Gabbay Heart valve prosthesis and sutureless implantation of a heart valve prosthesis
US20050010287A1 (en) * 2000-09-20 2005-01-13 Ample Medical, Inc. Devices, systems, and methods for supplementing, repairing, or replacing a native heart valve leaflet
US20100249921A1 (en) * 2000-11-09 2010-09-30 Cohn William E Cardiac Valve Procedure Methods and Devices
US20030028247A1 (en) * 2001-01-29 2003-02-06 Cali Douglas S. Method of cutting material for use in implantable medical device
US6503272B2 (en) * 2001-03-21 2003-01-07 Cordis Corporation Stent-based venous valves
US6682558B2 (en) * 2001-05-10 2004-01-27 3F Therapeutics, Inc. Delivery system for a stentless valve bioprosthesis
US20050043790A1 (en) * 2001-07-04 2005-02-24 Jacques Seguin Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body
US20050033398A1 (en) * 2001-07-31 2005-02-10 Jacques Seguin Assembly for setting a valve prosthesis in a corporeal duct
US20030036791A1 (en) * 2001-08-03 2003-02-20 Bonhoeffer Philipp Implant implantation unit and procedure for implanting the unit
US6986742B2 (en) * 2001-08-21 2006-01-17 Boston Scientific Scimed, Inc. Pressure transducer protection valve
US20080021552A1 (en) * 2001-10-09 2008-01-24 Shlomo Gabbay Apparatus To Facilitate Implantation
US20040039436A1 (en) * 2001-10-11 2004-02-26 Benjamin Spenser Implantable prosthetic valve
US6689144B2 (en) * 2002-02-08 2004-02-10 Scimed Life Systems, Inc. Rapid exchange catheter and methods for delivery of vaso-occlusive devices
US20040019374A1 (en) * 2002-05-10 2004-01-29 Hikmat Hojeibane Frame based unidirectional flow prosthetic implant
US20040034411A1 (en) * 2002-08-16 2004-02-19 Quijano Rodolfo C. Percutaneously delivered heart valve and delivery means thereof
US7335218B2 (en) * 2002-08-28 2008-02-26 Heart Leaflet Technologies, Inc. Delivery device for leaflet valve
US20070027518A1 (en) * 2003-04-01 2007-02-01 Case Brian C Percutaneously deployed vascular valves
US7175656B2 (en) * 2003-04-18 2007-02-13 Alexander Khairkhahan Percutaneous transcatheter heart valve replacement
US6989027B2 (en) * 2003-04-30 2006-01-24 Medtronic Vascular Inc. Percutaneously delivered temporary valve assembly
US20060009841A1 (en) * 2003-05-05 2006-01-12 Rex Medical Percutaneous aortic valve
US7316706B2 (en) * 2003-06-20 2008-01-08 Medtronic Vascular, Inc. Tensioning device, system, and method for treating mitral valve regurgitation
US20070016286A1 (en) * 2003-07-21 2007-01-18 Herrmann Howard C Percutaneous heart valve
US20050027348A1 (en) * 2003-07-31 2005-02-03 Case Brian C. Prosthetic valve devices and methods of making such devices
US6991649B2 (en) * 2003-08-29 2006-01-31 Hans-Hinrich Sievers Artificial heart valve
US20070010878A1 (en) * 2003-11-12 2007-01-11 Medtronic Vascular, Inc. Coronary sinus approach for repair of mitral valve regurgitation
US20060004469A1 (en) * 2004-06-16 2006-01-05 Justin Sokel Tissue prosthesis processing technology
US20060004439A1 (en) * 2004-06-30 2006-01-05 Benjamin Spenser Device and method for assisting in the implantation of a prosthetic valve
US20080015671A1 (en) * 2004-11-19 2008-01-17 Philipp Bonhoeffer Method And Apparatus For Treatment Of Cardiac Valves
US20090012600A1 (en) * 2005-04-05 2009-01-08 Mikolaj Witold Styrc Kit Which Is Intended to Be Implanted in a Blood Vessel, and Associated Tubular Endoprosthesis
US20070005131A1 (en) * 2005-06-13 2007-01-04 Taylor David M Heart valve delivery system
US20070027533A1 (en) * 2005-07-28 2007-02-01 Medtronic Vascular, Inc. Cardiac valve annulus restraining device
US20070038295A1 (en) * 2005-08-12 2007-02-15 Cook Incorporated Artificial valve prosthesis having a ring frame
US20070043431A1 (en) * 2005-08-19 2007-02-22 Cook Incorporated Prosthetic valve
US20090048656A1 (en) * 2005-11-09 2009-02-19 Ning Wen Delivery Device for Delivering a Self-Expanding Stent
US20090005863A1 (en) * 2006-02-16 2009-01-01 Goetz Wolfgang Minimally invasive heart valve replacement
US20080004696A1 (en) * 2006-06-29 2008-01-03 Valvexchange Inc. Cardiovascular valve assembly with resizable docking station
US20080048656A1 (en) * 2006-07-14 2008-02-28 Fengshun Tan Thermal controlling method, magnetic field generator and mri apparatus
US20090054976A1 (en) * 2007-08-20 2009-02-26 Yosi Tuval Stent loading tool and method for use thereof
US20100036479A1 (en) * 2008-04-23 2010-02-11 Medtronic, Inc. Stented Heart Valve Devices

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8070801B2 (en) 2001-06-29 2011-12-06 Medtronic, Inc. Method and apparatus for resecting and replacing an aortic valve
US8623077B2 (en) 2001-06-29 2014-01-07 Medtronic, Inc. Apparatus for replacing a cardiac valve
US8956402B2 (en) 2001-06-29 2015-02-17 Medtronic, Inc. Apparatus for replacing a cardiac valve
US20130105675A1 (en) * 2011-10-28 2013-05-02 Mitutoyo Corporation Displacement detecting device, displacement detecting method, and computer-readable medium
US8981282B2 (en) * 2011-10-28 2015-03-17 Mitutoyo Corporation Displacement detecting device, displacement detecting method, and computer-readable medium
US9717831B2 (en) 2014-12-19 2017-08-01 Heartware, Inc. Guidewire system and method of pump installation using same

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US6769434B2 (en) 2004-08-03 grant

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