New! View global litigation for patent families

US20100179589A1 - Rapidly eroding anchor - Google Patents

Rapidly eroding anchor Download PDF

Info

Publication number
US20100179589A1
US20100179589A1 US12684569 US68456910A US2010179589A1 US 20100179589 A1 US20100179589 A1 US 20100179589A1 US 12684569 US12684569 US 12684569 US 68456910 A US68456910 A US 68456910A US 2010179589 A1 US2010179589 A1 US 2010179589A1
Authority
US
Grant status
Application
Patent type
Prior art keywords
anchor
closure
element
lumen
portion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12684569
Inventor
Wouter E. Roorda
Laveille K. Voss
Kelly J. McCrystle
Karim S. Osman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Vascular Inc
Original Assignee
Abbott Vascular Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/042Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/048Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/06Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004(bio)absorbable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/0061Implements located only on one side of the opening
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A61B2017/00623Introducing or retrieving devices therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00637Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for sealing trocar wounds through abdominal wall
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646Type of implements
    • A61B2017/00654Type of implements entirely comprised between the two sides of the opening
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646Type of implements
    • A61B2017/00659Type of implements located only on one side of the opening
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646Type of implements
    • A61B2017/00663Type of implements the implement being a suture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646Type of implements
    • A61B2017/00668Type of implements the implement being a tack or a staple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

Abstract

An anchor for using a closure device includes a body being configured to move from a pre-deployed state to a deployed state. In the pre-deployed state, the body has a first width aspect relative to a direction of deployment and a second width aspect in the deployed state relative to the direction of deployment, the second width aspect being greater than the first width aspect and wherein the body is formed from a rapidly eroding material configured to erode through dissolution within a body lumen.

Description

    CROSS-REFERENCE TO RELATED APPLICATIONS
  • [0001]
    This patent application claims the benefit of and priority to U.S. Provisional Patent Application Ser. No. 61/143,751, entitled “Vessel Closure Devices and Methods,” filed Jan. 9, 2009, the disclosure of which is incorporated herein by reference in its entirety.
  • BACKGROUND
  • [0002]
    1. Technical Field
  • [0003]
    The present disclosure relates generally to medical devices and their methods of use. In particular, the present disclosure relates to vessel closure systems and devices and corresponding methods of use.
  • [0004]
    2. The Technology
  • [0005]
    Catheterization and interventional procedures, such as angioplasty or stenting, generally are performed by inserting a hollow needle through a patient's skin and tissue into the vascular system. A guidewire may be advanced through the needle and into the patient's blood vessel accessed by the needle. The needle is then removed, enabling an introducer sheath to be advanced over the guidewire into the vessel, e g in conjunction with or subsequent to a dilator.
  • [0006]
    A catheter or other device may then be advanced through a lumen of the introducer sheath and over the guidewire into a position for performing a medical procedure. Thus, the introducer sheath may facilitate introducing various devices into the vessel, while minimizing trauma to the vessel wall and/or minimizing blood loss during a procedure.
  • [0007]
    Upon completing the procedure, the devices and introducer sheath would be removed, leaving a puncture site in the vessel wall. Traditionally, external pressure would be applied to the puncture site until clotting and wound sealing occur. However, the patient must remain bedridden for a substantial period after clotting to ensure closure of the wound. This procedure may be time consuming and expensive, requiring as much as an hour of a physician's or nurse's time. It is also uncomfortable for the patient and requires that the patient remain immobilized in the operating room, catheter lab, or holding area. In addition, a risk of hematoma exists from bleeding before hemostasis occurs.
  • BRIEF SUMMARY
  • [0008]
    An anchor for using a closure device may include a body being configured to move from a pre-deployed state to a deployed state. In the pre-deployed state, the body has a first width aspect relative to a direction of deployment and a second width aspect in the deployed state relative to the direction of deployment, the second width aspect being greater than the first width aspect and wherein the body is formed from a rapidly eroding material configured to erode through dissolution within a body lumen.
  • [0009]
    A method of closing a puncture in a wall of a body lumen may include advancing an anchor in a deployment direction through the anchor, the anchor having a first width aspect relative to the deployment direction, deploying the anchor distally of the wall of the body lumen to cause the anchor to move to have a second width aspect relative to the deployment direction, the second width aspect being larger than the first width aspect, drawing the anchor distally into engagement with a distal side of the wall of the body lumen, and deploying a closure element into the wall of the body lumen, wherein the anchor is formed from a rapidly eroding material that dissolves in the body lumen in less than twelve hours.
  • [0010]
    A closure device system may include a delivery sheath, a rapidly eroding anchor at least partially disposed within the delivery sheath in an initial configuration, the closure member comprising one or more sugars, a suture element coupled to the closure member and disposed at least partially through the delivery sheath, and a pusher disposed at least partially within the delivery sheath and configured to deploy the anchor member from a distal end of the delivery sheath.
  • [0011]
    It is to be understood that both the foregoing general description and the following detailed description are exemplary and are intended to provide further explanation of the invention claimed.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0012]
    To further clarify the above and other advantages and features of the present disclosure, a more particular description of the disclosure will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings. It is appreciated that these drawings depict only illustrated embodiments of the disclosure and are therefore not to be considered limiting of its scope. The disclosure will be described and explained with additional specificity and detail through the use of the accompanying drawings in which:
  • [0013]
    FIGS. 1A-1C illustrate a closure device in which a rapidly eroding anchor can be implemented according to one example;
  • [0014]
    FIGS. 1D-1F illustrate a method of closing a puncture in a wall of a body lumen in which a rapidly eroding anchor can be implemented;
  • [0015]
    FIGS. 2A-2E illustrate a closure device and a method for closing a puncture in a wall of a body lumen in which a rapidly eroding anchor can be implemented according to one example; and
  • [0016]
    FIG. 3 illustrates a closure device and a method for closing a puncture in a wall of a body lumen in which a rapidly eroding anchor can be implemented according to one example.
  • DETAILED DESCRIPTION
  • [0017]
    The present disclosure relates to devices, systems, and methods for closing an opening in a body lumen. For example, the present disclosure includes an anchor, such as an intra-arterial “foot,” comprising a rapidly eroding material. The anchor may be passed through an opening defined in a wall of a body lumen and deployed. The anchor can then be drawn proximally to draw the anchor into contact with a distal side of the body lumen wall. A closure element can then be deployed to close the puncture.
  • [0018]
    In at least one example, once deployed within a body lumen, the anchor may dissolve in less than a day or even less than an hour as desired. The rapid erosion of the anchor can allow the anchor to be left in place after the closure element has been deployed by obviating the need for removal of the anchor. By leaving the anchor in place until it dissolves, damage that may occur by drawing the anchor through the closed puncture and/or the deployed closure element can be reduced or eliminated.
  • [0019]
    In addition, the erosion time of the anchor may fall within the time frame of the action of an anti-thrombotic medication being used in conjunction with the treatment of a patient. Accordingly, the closure element of the present disclosure may reduce the risk of formation of intra-arterial clots associated with the closure of the body lumen opening.
  • [0020]
    Reference is now made to FIG. 1A, which illustrates a closure device 100 according to one example. As shown in FIG. 1A, the closure device 100 may include a delivery sheath 110 and a pusher 120 that are configured to cooperate to deploy an anchor 130, such as an intra-arterial foot, and a closure element 140, such as a plug, and a suture element 150. In at least one example, the delivery sheath 110 is configured to house the anchor 130 and the closure element 140 while the pusher 120 is configured to deploy the anchor 130 and/or the closure element 140 from the delivery sheath 110. The exemplary delivery sheath 110, pusher 120, anchor 130, and closure element 140 of FIG. 1A will be discussed in more detail with reference to FIG. 1B.
  • [0021]
    FIG. 1B illustrates an exploded view of the closure device 100. As shown in FIG. 1B, the delivery sheath 110 includes an outer housing 112 and a grip portion 114 while the pusher 120 includes a handle portion 122 and a shaft portion 124. An interior lumen 116 is defined in the outer housing 112 that is configured to receive the pusher 120 in such a manner as to allow the pusher 120 to be extended from and retracted within a distal end 112A of the outer housing 112. For example, the interior lumen 116 can include a first portion 116A configured to receive the shaft portion 124 of the pusher 120 while a second portion 116B of the interior lumen 116 can be configured to receive a distal end 124A of the shaft portion 124.
  • [0022]
    More specifically, the second portion 116B of the interior lumen 116 may have a larger width aspect than the width aspect of the first portion 116A. The width aspects of the first portion 116A and the second portion 116B can be the diameters thereof or other cross sectional profiles that are generally transverse to a center axis C of the delivery sheath 110. For ease of reference, the center axis C of the delivery sheath 110 will be referenced in describing the position and movement of the other components described herein. In the illustrated example, the interior lumen 116 may transition from the smaller diameter of the first portion 116A to a second larger diameter of the second portion 116B at a shoulder 118.
  • [0023]
    Such a configuration can allow the pusher 120 to translate axially relative to the delivery sheath 110 within a desired range of motion. In particular, the handle portion 122 can translate within the second portion 116B of the interior lumen 116 to advance the shaft portion 124 within the outer housing 112 to thereby move the distal end 124A of the shaft portion 124 relative to the distal end 112A of the outer housing 112. Interaction between the handle portion 122 and the shoulder 118 can help ensure the distal end 124A does not extend beyond a desired position within the outer housing 112.
  • [0024]
    In the illustrated example, the first portion 116A may also be configured to receive the anchor 130 and the closure element 140 proximally of the distal end 124A of the shaft portion 124. Accordingly, as the distal end 124A of the shaft portion 124 is advanced toward the distal end 112A of the outer housing 112, the distal end 124A of the shaft portion 124 can engage the anchor 130 and/or the closure element 140 to move the anchor 130 and/or the closure element 140 distally from the outer housing 112.
  • [0025]
    The anchor 130 can be configured to move from a pre-deployed state having a pre-deployed width aspect to a deployed state having a deployed width aspect. The deployed width aspect may be greater than the pre-deployed width aspect. The anchor 130 can have any configuration that allows for this. In the illustrated example, anchor 130 is configured to rotate or be rotated between the pre-deployed state and the deployed state. In other examples, the anchor 130 may be configured to unfold from a configuration have a pre-deployed width aspect to a deployed state having a greater width aspect. For example, one or more arms may be configured to unfold and fold about a plurality of pivot or hinge points.
  • [0026]
    As shown in FIG. 1B, the anchor 130 includes leg members 132, 134 that define a major axis 136 of the anchor 130. The anchor 130 can further include an eyelet 138 coupled to one or both of the leg members 132, 134. The eyelet 138 can be located at a position that causes the anchor 130 to rotate when a force acting initially parallel to the major axis 136 is exerted on the eyelet 138. Such a configuration can allow the anchor 130 to move from a state in which the major axis 136 is aligned with the central axis C to a state in which the major axis 136 is oriented more obliquely to the central axis C, such as generally perpendicular to the central axis C.
  • [0027]
    This rotation can be accomplished by applying a distally acting force on the anchor 130 to move the anchor 130 out of the outer housing 112 and then a proximally directed force to the anchor 130 by way of the eyelet 138. In at least one example, the distally acting force applied to the anchor 130 can be provided from the pusher 120 by way of the closure element 140 while the proximally directed force can be applied by way of the suture element 150. The anchor 130 can thus be used to position the closure device 100 for deployment of the closure element 140.
  • [0028]
    In one embodiment, the closure element 140 may be configured to close an opening in a lumen as well as at least partially obstruct a tissue tract leading from an external surface of the tissue to the lumen. The shape of the closure element 140 may be configured to be housed within the first portion 116A of the interior lumen 116. For example, the closure element 140 may conform to the shape of the interior lumen 116. In one embodiment, the closure element 140 may be cylindrical in shape prior to being deployed from the delivery sheath 110. Once deployed from the delivery sheath 110, the closure element 140 may be deformable to conform to any desired shape to close an opening in a body lumen and/or the tissue tract leading to the lumen opening.
  • [0029]
    As shown, the example pusher 120 can be coupled to the closure element 140 and/or anchor 130 by way of the suture element 150. In particular, the suture element 150 can loop through the anchor 130 such that the suture element 150 has two free ends that pass through or near the closure element 140, and extend proximally into or beyond the handle portion 122 of the pusher 120. In at least one example, the free ends of the suture element 150 pass through separate portions or channels of the closure element 140. In one embodiment, the pusher 120 can have a suture lumen 126 defined therein that extends through the shaft portion 124 and extends proximally to or even through the handle portion 122. The suture element 150 can be extended from the closure element 140 and into the pusher 120 by way of the suture lumen 126.
  • [0030]
    In one embodiment, the delivery sheath 110 may include a guidewire lumen 160 with a proximal guidewire port 162 therein near the proximal end 112B of the outer housing 112 and a distal guidewire port 164 near the distal end 112A of the outer housing 112. The guidewire lumen 160 may be at least partially integrated or entirely distinct from the interior lumen 116 of the delivery sheath 110. Accordingly, a guidewire can enter the proximal guidewire port 162, pass through the guidewire lumen 160, and exit the distal guidewire port 164. As a result, the example closure device 100 can advance over a guidewire and into position with a lumen opening as part of a method to close the lumen opening. One such method will now be discussed in more detail with reference to FIGS. 1C-1F.
  • [0031]
    Reference is now made to FIG. 1C, which illustrates a step in the process of deploying the anchor 130. As shown in FIG. 1C, the delivery sheath 110 can be positioned to move the distal end 112A of the outer housing 112 through a tract 170 defined in tissue 172 and into proximity with a lumen 174 and a puncture 176 defined in a lumen wall 178 in particular.
  • [0032]
    Thereafter, as shown in FIG. 1D, the pusher 120 can be manipulated as described above to cause the anchor 130 to be pushed out of the distal end 112A of the outer housing 112. For example, the pusher 120 may push the closure element 140 which may, in turn, push the anchor 130 distally relative to the outer housing 112, thereby deploying the anchor 130 from the distal end 112A of the outer housing 112. In one embodiment, once deployed, the anchor 130 may rotate or be rotated from a first orientation, in which the major axis 136 of the anchor 130 is at a small angle or generally parallel with the outer housing 112 and generally perpendicular to the lumen wall 178 as shown in FIG. 1C, to a second orientation in which the major axis 136 of the anchor 130 is generally parallel with the lumen 170 and at a greater angle or generally perpendicular to the delivery sheath 110 as shown in FIG. 1D.
  • [0033]
    In particular, as shown in FIG. 1D, once the anchor 130 is pushed from the distal end 112A of the outer housing 112, the anchor 130 may rotate or be rotated to the second orientation, such as by tension applied to by the suture element 150 to the anchor 130 by way of the eyelet 138. The anchor 130 can then be drawn in the proximal direction to secure the anchor 130 against a distal surface 178A of the lumen wall 178. The anchor 130 may comprise any of a number of different materials. In one example, the anchor 130 may comprise a bioabsorbable material. In a further embodiment, the anchor 130 may comprise a rapidly eroding material as disclosed in more detail herein.
  • [0034]
    As also shown in FIG. 1D, the anchor 130 can be used to stabilize tissue around the puncture 176 in order to facilitate closure of the puncture 176. In particular, once the anchor 130 is deployed, the anchor 130 may then be secured against a distal side 178A of the lumen wall 178 by pulling the suture element 150, which is coupled to the anchor 130, proximally. In one example, a suture lock (not shown) can be utilized to help maintain the tension in the suture element 150. Once the anchor 130 is secured against the distal side 178A of the lumen wall 178, the outer housing 112 may be advanced distally. In particular, the outer housing 112 can be advanced to exert a force against a proximal side 178B of the lumen wall 178. The combination of the forces exerted by the anchor 130 and the outer housing 112 on the lumen wall 178 may result in a compressive force on the tissue near the puncture 176. As a result, the puncture 176 may be compressed and/or located by the delivery sheath 110 and the outer housing 112 in particular. This may allow an adjustable sandwiching and location of the lumen opening by the combination of tension in the suture element 150 and compression created by the delivery sheath 110.
  • [0035]
    With the anchor 130 deployed, the pusher 120 may then deploy the closure element 140 within the puncture 176 and/or the tract 170 near a proximal side 178B of the lumen wall 178. In particular, as shown in FIG. 1E the pusher 120 can be advanced distally, the delivery sheath 110 can be drawn proximally, and/or some combination of such movements can be used to move the closure element 140 distally out of the outer housing 112 and into contact with the proximal side 178B of the lumen wall 178 adjacent the puncture 176.
  • [0036]
    In such a step, the lumen wall 178 is positioned between the anchor 130 and the closure element 140. Thus, the closure element 140 can be positioned to reduce or stop the flow of fluid out of the tract 170 by covering the puncture 176 and/or obstructing the tract 170.
  • [0037]
    In one embodiment, the pusher 120 remains in continuous contact with the closure element 140 throughout the deployment process. Such a configuration can allow the anchor 130 and/or closure element 140 to be deployed by advancing the pusher 120 in a single direction. By facilitating deployment of the anchor 130 and closure element 140 using one-way movement of the pusher 120, and by utilizing a single pusher 120, the closure device 100 may result in a quicker and easier deployment of the anchor 130 and/or closure element 140.
  • [0038]
    The engagement of the anchor 130 and the closure element 140 to the lumen wall 178 may be secured in any desired manner. In at least one example, the free ends of the suture element 150 may pass from the anchor 130 through the closure element 140. In such an example, a suture lock and/or a knot pusher can be used to advance a knot into proximity with the closure element 140 and tighten the knot to thereby maintain tension between the anchor 130 and the closure element 140. A suture cutter can then sever the suture element 150. A suture lock, a knot pusher, and/or a suture cutter can be advanced through a suture lumen 126 defined in the pusher 120 either before or after the delivery sheath 110 and the pusher 120 are withdrawn from the tract 170. As a result, the suture element anchor 130, closure element 140, and suture element 150 can remain in the tissue tract 170 as shown in FIG. 1F.
  • [0039]
    As previously introduced, the anchor 130 can be formed of a rapidly eroding material that allows the anchor 130 to be left in place within the lumen 174. The composition of the anchor 130 allows the anchor 130 to remain in position for a long enough period to enable the closure procedure and a short enough period to allow sufficient erosion of the anchor 130 while the patient is still under physician control or in the hospital. This time period can therefore be in a range of roughly between 30 minutes and 12 hours. The anchor 130 may be formed of a material that is strong enough to allow for secure anchoring of a closure element, such as the plug and/or other closure elements described below.
  • [0040]
    Further, the anchor 130 may be formed of a material that is biocompatible in an intravascular environment and non-thrombogenic. An anchor with these characteristics may be obtained by using a mechanism of dissolution rather than chemical degradation. Rapidly dissolving compounds that are suitable include, but are not limited to, sugars and sugar-derivatives like sugar-alcohols. Representative examples are sugars like glucose, fructose, lactose, maltose, and sugar alcohols like mannitol, sorbitol and isomalt. Strength can be added to the formulation by including a polymeric component, such as poly-vinylpyrrolidone, poly-ethyleneglycol, or a polysaccharide like starch, hydroxyethylstarch, dextran or dextran sulfate. Sugar alcohols such as mannitol, sorbitol, and isomalt have relatively low melting points, and form good solvents for the polysaccharides. This can facilitate manufacturing, since a simple melt process can be used. Various mixtures of these components are possible, resulting in potentially different anchor properties. Hydroxyethyl starch has a relatively low glass transition temperature, and so has a mannitol-sorbitol mixture. A solution of hydroxyethyl starch in mannitol-sorbitol, when solidified, may have a glass transition below body temperature, which will create a tough, but not brittle anchor. On the other end of the spectrum, a mixture of dextran with isomalt has a much higher glass transition, resulting in a very hard and strong anchor, but with higher brittleness. Since all these components are miscible, a wide range of properties can be achieved by mixing them in corresponding proportions to achieve the desired properties.
  • [0041]
    In one embodiment, the rapidly eroding material can be configured to be at least partially porous and/or micro-porous. Accordingly, one or more beneficial agents can be incorporated into at least one of the pores of the rapidly eroding material. For example, the beneficial agents may include anti-clotting agents, such as heparin, anti-inflammatory agents, and/or other beneficial agents. One method for producing a porous rapidly eroding material may include freeze drying the rapidly eroding material. In particular, in one example embodiment, acetic acid may be used as a solvent for freeze drying the rapidly eroding material. Polymers, such as PLGA, which are soluble in acetic acid, may be used as part of the freeze-drying process.
  • [0042]
    In a further embodiment, a micro-porous silicon may be used. In particular, the micro-porous silicon may be prepared with various degradation rates, including rapidly degrading forms. The micro-porous silicon may be sufficiently strong to be used in an anchor, such as a bioerodible foot, and/or may also have sufficient porosity to allow incorporation of beneficial agents. For example, in one embodiment, it may be desirable to incorporate a hydrophobic heparin derivative, such as benzalkonium heparin, into the porosity of the anchor because of its low solubility. The closure element 140 may comprise any number of different materials suitable for use as a plug.
  • [0043]
    FIG. 2A illustrates a closure device 200 in which an anchor 130′ similar to the anchor 130 described above may be implemented. In the illustrated example, the closure device 200 can include a delivery sheath 110′ having an outer housing 112′ and a grip portion 114′. An interior lumen 116′ is defined in the outer housing 112′ configured to house the anchor 130′. The closure device 200 further includes deployment assembly 210 that includes a garage sheath 220 configured to house an actuator member 230, which in turn can be configured to house a carrier tube 240, which in turn is configured to house a pusher 120′.
  • [0044]
    The pusher 120′ can be configured to translate axially within the carrier tube 240 to deploy the anchor 130′ from the closure device 200. A closure element 250 is configured to be positioned on the carrier tube 240. As will be discussed in more detail below, distal movement of the actuator member 230 relative to the carrier tube 240 may deploy the closure element 250.
  • [0045]
    In the illustrated example, the garage sheath 220 includes a housing portion 222 coupled to a plunger portion 224. The first plunger portion 224 can be positioned proximally of the grip portion 114′ of the delivery sheath 110. The actuator member 230 can include a housing portion 232 and a second plunger portion 234. The carrier tube 240 can also include a housing portion 242 and a third plunger portion 244. The pusher 120′ includes a handle portion 122′ and a shaft portion 124′.
  • [0046]
    As shown in FIG. 2B, the pusher 120′ can be used to deploy the anchor 130′ from the delivery sheath 110′ using a suture element 150′ in a similar manner as described above. Once the anchor 130′ is deployed, the first plunger portion 224 can be advanced proximally relative to the delivery sheath 110′ along with the second plunger portion 234 and the third plunger portion 244 to position the deployment assembly 210 in proximity with the lumen wall 178.
  • [0047]
    Thereafter, as shown in FIG. 2C, the first plunger portion 224 may be drawn proximally toward the second plunger portion 234 and the third plunger portion 244, the second plunger portion 234 and the third plunger portion 244 may be advanced distally, and/or some combination of those movements may be performed to expose the actuator member 230 and the carrier tube 240 from the garage sheath 220 while maintaining the carrier tube 240 in engagement with the lumen wall 178. In such an example, the delivery sheath 110′ can remain in place to maintain the lumen wall 178 between the delivery sheath 110′ and the anchor 130′.
  • [0048]
    As shown in FIG. 2D, the second plunger portion 234 can then be advanced distally relative to the third plunger portion 244 to expand and deploy the closure element 250. In particular, as shown in FIG. 2D, the carrier tube 240 includes ramped portions 246. As the second plunger portion 234 advances distally relative to the third plunger portion 244, the actuator member 230 pushes the closure element 250 over the ramped portions 246 of the carrier tube, thereby expanding the closure element 250. Thereafter, the closure device 200 can be removed and the suture element 250 cut as described above.
  • [0049]
    Continued advancement of the actuator member 230 distally relative to the carrier tube 240 moves tissue-engaging portions 252 of the closure element 250 into engagement with the lumen wall 178. Further distal movement of the actuator member 230 pushes the closure element 250 distally of the carrier tube 240. In at least one example, the closure element 250 can be formed of a resilient material having a trained or default state having a narrow diameter. The closure element 250 can be partially expanded onto the carrier tube 240 prior deployment. As the closure element 250 moves distally from the carrier tube 240, the closure element 250 can move toward the trained or default state, thereby closing the puncture 176.
  • [0050]
    As shown in FIG. 2E, once the closure element 250 is deployed, a plug material 260 may be injected near the lumen wall and within the tract 170. A suture element 150′ may be secured, such as by knotting, and then severed, thereby leaving the anchor 130′, closure element 250, and plug 260 in place while the remaining components of the closure device 200 are retracted. Thereafter, the rapidly eroding material of the anchor 130′ may then dissolve into the fluid flow within the lumen. In another example, the anchor maybe dissolved soon after the procedure allowing the suture element 250 to be removed and obviating the use of the plug material 260. In still further examples, the anchor 130′ may be let go down stream by slipping off the suture from the anchor, thus leaving behind only the closure element 250.
  • [0051]
    FIG. 3 illustrates a closure device 200′ configured for use as an over-the wire deployment that is similar to the closure device 200 shown in FIGS. 2A-2E. The closure device 250′ may be advanced over a guidewire 300. In the example shown in FIG. 3, the delivery sheath 110′ and garage sheath 220 of FIGS. 2A-2E have been omitted. In such an example, the anchor 130′ can be housed within the carrier tube 240 and pushed distally using a pusher 120′ translating therein. Thereafter, the closure device 200′ can deploy the anchor 130′ and the closure element 250 in a similar manner as described above with reference to FIGS. 2A-2E by advancing an actuator member 230 relative to a carrier tube 240.
  • [0052]
    Embodiments of the closure element, the delivery sheath, and the like may include a material made from any of a variety of known suitable biocompatible materials, such as a biocompatible shape memory material (SMM). For example, the SMM may be shaped in a manner that allows for a delivery orientation while within the tube set, but may automatically retain the memory shape of the component once deployed into the tissue to close the opening. SMMs have a shape memory effect in which they may be made to remember a particular shape. Once a shape has been remembered, the SMM may be bent out of shape or deformed and then returned to its original shape by unloading from strain or heating. Typically, SMMs may be shape memory alloys (SMA) comprised of metal alloys, or shape memory plastics (SMP) comprised of polymers. The materials may also be referred to as being superelastic.
  • [0053]
    Usually, an SMA may have an initial shape that may then be configured into a memory shape by heating the SMA and conforming the SMA into the desired memory shape. After the SMA is cooled, the desired memory shape may be retained. This allows for the SMA to be bent, straightened, twisted, compacted, and placed into various contortions by the application of requisite forces; however, after the forces are released, the SMA may be capable of returning to the memory shape. The main types of SMAs are as follows: copper-zinc-aluminum; copper-aluminum-nickel; nickel-titanium (NiTi) alloys known as nitinol; nickel-titanium platinum; nickel-titanium palladium; and cobalt-chromium-nickel alloys or cobalt-chromium-nickel-molybdenum alloys known as elgiloy alloys. The temperatures at which the SMA changes its crystallographic structure are characteristic of the alloy, and may be tuned by varying the elemental ratios or by the conditions of manufacture. This may be used to tune the component so that it reverts to the memory shape to close the arteriotomy when deployed at body temperature and when being released from the tube set.
  • [0054]
    For example, the primary material of a closure element and the like may be of a NiTi alloy that forms superelastic nitinol. In the present case, nitinol materials may be trained to remember a certain shape, retained within the tube set, and then deployed from the tube set so that the tines penetrate the tissue as it returns to its trained shape and closes the opening. Also, additional materials may be added to the nitinol depending on the desired characteristic. The alloy may be utilized having linear elastic properties or non-linear elastic properties.
  • [0055]
    An SMP is a shape-shifting plastic that may be fashioned into a closure element in accordance with the present disclosure. Also, it may be beneficial to include at least one layer of an SMA and at least one layer of an SMP to form a multilayered body; however, any appropriate combination of materials may be used to form a multilayered device. When an SMP encounters a temperature above the lowest melting point of the individual polymers, the blend makes a transition to a rubbery state. The elastic modulus may change more than two orders of magnitude across the transition temperature (Ttr). As such, an SMP may be formed into a desired shape of an endoprosthesis by heating it above the Ttr, fixing the SMP into the new shape, and cooling the material below Ttr. The SMP may then be arranged into a temporary shape by force and then resume the memory shape once the force has been released. Examples of SMPs include, but are not limited to, biodegradable polymers, such as oligo(ε-caprolactone)diol, oligo(ρ-dioxanone)diol, and non-biodegradable polymers such as, polynorborene, polyisoprene, styrene butadiene, polyurethane-based materials, vinyl acetate-polyester-based compounds, and others yet to be determined. As such, any SMP may be used in accordance with the present disclosure.
  • [0056]
    The closure element, the delivery sheath, and the like may have at least one layer made of an SMM or suitable superelastic material and other suitable layers may be compressed or restrained in its delivery configuration within the garage tube or inner lumen, and then deployed into the tissue so that it transforms to the trained shape. For example, the closure element may be set in a trained shape that has a relative small diameter. The closure element can then be expanded and moved into engagement with a body lumen wall adjacent a puncture. The closure element can then be allowed to return to the trained state to close the puncture.
  • [0057]
    Also, a closure element, the delivery sheath or other aspects or components of the closure system may be comprised of a variety of known suitable deformable materials, including stainless steel, silver, platinum, tantalum, palladium, nickel, titanium, nitinol, having tertiary materials (U.S. 2005/0038500, which is incorporated herein by reference, in its entirety), niobium-tantalum alloy optionally doped with a tertiary material (U.S. 2004/0158309, 2007/0276488, and 2008/0312740, which are each incorporated herein by reference, in their entireties) cobalt-chromium alloys, or other known biocompatible materials. Such biocompatible materials may include a suitable biocompatible polymer in addition to or in place of a suitable metal.
  • [0058]
    In one embodiment, the closure element, the delivery sheath, and the like may be made from a superelastic alloy such as nickel-titanium or nitinol, and includes a ternary element selected from the group of chemical elements consisting of iridium, platinum, gold, rhenium, tungsten, palladium, rhodium, tantalum, silver, ruthenium, or hafnium. The added ternary element improves the radiopacity of the nitinol.
  • [0059]
    In one embodiment, the closure element, the delivery sheath, and the like may be made at least in part of a high strength, low modulus metal alloy comprising Niobium, Tantalum, and at least one element selected from the group consisting of Zirconium, Tungsten, and Molybdenum.
  • [0060]
    In further embodiments, the closure element, the delivery sheath, and the like may be made from or be coated with a biocompatible polymer. Examples of such biocompatible polymeric materials may include hydrophilic polymer, hydrophobic polymer biodegradable polymers, bioabsorbable polymers, and monomers thereof. Examples of such polymers may include nylons, poly(alpha-hydroxy esters), polylactic acids, polylactides, poly-L-lactide, poly-DL-lactide, poly-L-lactide-co-DL-lactide, polyglycolic acids, polyglycolide, polylactic-co-glycolic acids, polyglycolide-co-lactide, polyglycolide-co-DL-lactide, polyglycolide-co-L-lactide, polyanhydrides, polyanhydride-co-imides, polyesters, polyorthoesters, polycaprolactones, polyesters, polyanydrides, polyphosphazenes, polyester amides, polyester urethanes, polycarbonates, polytrimethylene carbonates, polyglycolide-co-trimethylene carbonates, poly(PBA-carbonates), polyfumarates, polypropylene fumarate, poly(p-dioxanone), polyhydroxyalkanoates, polyamino acids, poly-L-tyrosines, poly(beta-hydroxybutyrate), polyhydroxybutyrate-hydroxyvaleric acids, polyethylenes, polypropylenes, polyaliphatics, polyvinylalcohols, polyvinylacetates, hydrophobic/hydrophilic copolymers, alkylvinylalcohol copolymers, ethylenevinylalcohol copolymers (EVAL), propylenevinylalcohol copolymers, polyvinylpyrrolidone (PVP), combinations thereof, polymers having monomers thereof, or the like.
  • [0061]
    The present disclosure may be embodied in other specific forms without departing from its spirit or essential characteristics. The described embodiments are to be considered in all respects only as illustrative and not restrictive. The scope of the disclosure is, therefore, indicated by the appended claims rather than by the foregoing description. All changes which come within the meaning and range of equivalency of the claims are to be embraced within their scope.

Claims (23)

  1. 1. An anchor for using a closure device, the anchor comprising:
    a body being configured to move from a pre-deployed state to a deployed state, wherein in the pre-deployed state the body has a first width aspect relative to a direction of deployment and a second width aspect in the deployed state relative to the direction of deployment, the second width aspect being greater than the first width aspect and wherein the body is formed from a rapidly eroding material configured to erode through dissolution within a body lumen.
  2. 2. The anchor of claim 1, wherein the body is configured to erode in less than twelve hours.
  3. 3. The anchor of claim 1, wherein the body is configured to erode in less than one hour.
  4. 4. The anchor of claim 1, wherein the body includes a major axis and wherein the body is configured to rotate in response to a force applied parallel to the major axis.
  5. 5. The anchor of claim 1, wherein the rapidly eroding material includes at least one of a sugar and a sugar-derivative.
  6. 6. The anchor of claim 5, wherein the sugar derivative includes sugar alcohols including mannitol, sorbitol, and isomalt.
  7. 7. The anchor of claim 5, wherein the sugar includes at least one of a group including glucose, fructose, lactose and maltose.
  8. 8. The anchor of claim 1, wherein the body further includes at least one polymeric component.
  9. 9. The anchor of claim 8, wherein the polymeric component includes at least one of poly-vinylpyrrolidone, poly-ethyleneglycol, hydroxyethyl starch, dextran or dextran sulfate.
  10. 10. The anchor of claim 1, wherein the rapidly eroding material is water soluble.
  11. 11. The anchor of claim 1, wherein the rapidly eroding material forms a crystalline matrix.
  12. 12. The anchor of claim 1, wherein the rapidly eroding material forms a glass structure.
  13. 13. The anchor of claim 1, wherein the rapidly eroding material includes a plurality of pores.
  14. 14. The anchor of claim 13, wherein at least one of the pores includes at least one beneficial agent.
  15. 15. The anchor of claim 13, wherein the anchor member includes at least one of poly-vinyl pyrrolidone, hyaluronic acid, dextran, hydrogel, heparin, and benzalkonium heparin.
  16. 16. The closure device of claim 1, wherein the anchor member is formed using a freeze-drying process.
  17. 17. A method of closing a puncture in a wall of a body lumen, comprising:
    advancing an anchor in a deployment direction through the anchor, the anchor having a first width aspect relative to the deployment direction;
    deploying the anchor distally of the wall of the body lumen to cause the anchor to move to have a second width aspect relative to the deployment direction, the second width aspect being larger than the first width aspect;
    drawing the anchor distally into engagement with a distal side of the wall of the body lumen; and
    deploying a closure element into the wall of the body lumen, wherein the anchor is formed from a rapidly eroding material that dissolves in the body lumen in less than twelve hours.
  18. 18. The method of claim 17, wherein rapidly eroding material dissolves in the body lumen in less than one hour.
  19. 19. The method of claim 17, wherein deploying a closure element includes deploying an expandable plug.
  20. 20. The method of claim 17, wherein deploying a closure element includes deploying tines into the wall of the body lumen.
  21. 21. A closure device system comprising:
    a delivery sheath;
    a rapidly eroding anchor at least partially disposed within the delivery sheath in an initial configuration, the closure member comprising one or more sugars;
    a suture element coupled to the closure member and disposed at least partially through the delivery sheath; and
    a pusher disposed at least partially within the delivery sheath and configured to deploy the anchor member from a distal end of the delivery sheath.
  22. 22. The closure device system of claim 21, further comprising an expandable plug configured to be positioned between the anchor and the pusher.
  23. 23. The closure device system of claim 21, further comprising an expandable closure element configured to be moved between an expanded state and a restricted state to close a puncture in a wall of a body lumen.
US12684569 2009-01-09 2010-01-08 Rapidly eroding anchor Abandoned US20100179589A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US14375109 true 2009-01-09 2009-01-09
US12684569 US20100179589A1 (en) 2009-01-09 2010-01-08 Rapidly eroding anchor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12684569 US20100179589A1 (en) 2009-01-09 2010-01-08 Rapidly eroding anchor
US14466576 US9314230B2 (en) 2009-01-09 2014-08-22 Closure device with rapidly eroding anchor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US14466576 Continuation US9314230B2 (en) 2009-01-09 2014-08-22 Closure device with rapidly eroding anchor

Publications (1)

Publication Number Publication Date
US20100179589A1 true true US20100179589A1 (en) 2010-07-15

Family

ID=42319600

Family Applications (2)

Application Number Title Priority Date Filing Date
US12684569 Abandoned US20100179589A1 (en) 2009-01-09 2010-01-08 Rapidly eroding anchor
US14466576 Active US9314230B2 (en) 2009-01-09 2014-08-22 Closure device with rapidly eroding anchor

Family Applications After (1)

Application Number Title Priority Date Filing Date
US14466576 Active US9314230B2 (en) 2009-01-09 2014-08-22 Closure device with rapidly eroding anchor

Country Status (1)

Country Link
US (2) US20100179589A1 (en)

Cited By (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7879071B2 (en) 2000-12-07 2011-02-01 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7901428B2 (en) 2000-01-05 2011-03-08 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US7918873B2 (en) 2001-06-07 2011-04-05 Abbott Vascular Inc. Surgical staple
US7931669B2 (en) 2000-01-05 2011-04-26 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US8007512B2 (en) 2002-02-21 2011-08-30 Integrated Vascular Systems, Inc. Plunger apparatus and methods for delivering a closure device
US8182497B2 (en) 2000-12-07 2012-05-22 Integrated Vascular Systems, Inc. Closure device
US8192459B2 (en) 2002-06-04 2012-06-05 Abbott Vascular Inc. Blood vessel closure clip and delivery device
US8202294B2 (en) 2003-01-30 2012-06-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8202283B2 (en) 2002-12-31 2012-06-19 Integrated Vascular Systems, Inc. Methods for manufacturing a clip and clip
US8202293B2 (en) 2003-01-30 2012-06-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
WO2012061486A3 (en) * 2010-11-02 2012-07-12 Transluminal Technologies, Inc. Closure device, deployment apparatus, and method of deploying a closure device
US8226681B2 (en) 2007-06-25 2012-07-24 Abbott Laboratories Methods, devices, and apparatus for managing access through tissue
US8303624B2 (en) 2010-03-15 2012-11-06 Abbott Cardiovascular Systems, Inc. Bioabsorbable plug
US8313497B2 (en) 2005-07-01 2012-11-20 Abbott Laboratories Clip applier and methods of use
US8323312B2 (en) 2008-12-22 2012-12-04 Abbott Laboratories Closure device
US20130053884A1 (en) * 2011-08-26 2013-02-28 Abbott Cardiovascular Systems, Inc. Suture fastener combination device
US8398676B2 (en) 2008-10-30 2013-03-19 Abbott Vascular Inc. Closure device
US8398656B2 (en) 2003-01-30 2013-03-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8556930B2 (en) 2006-06-28 2013-10-15 Abbott Laboratories Vessel closure device
US8590760B2 (en) 2004-05-25 2013-11-26 Abbott Vascular Inc. Surgical stapler
US8597325B2 (en) 2000-12-07 2013-12-03 Integrated Vascular Systems, Inc. Apparatus and methods for providing tactile feedback while delivering a closure device
US8603116B2 (en) 2010-08-04 2013-12-10 Abbott Cardiovascular Systems, Inc. Closure device with long tines
US8672953B2 (en) 2007-12-17 2014-03-18 Abbott Laboratories Tissue closure system and methods of use
US8690910B2 (en) 2000-12-07 2014-04-08 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8758400B2 (en) 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Closure system and methods of use
US8758398B2 (en) 2006-09-08 2014-06-24 Integrated Vascular Systems, Inc. Apparatus and method for delivering a closure element
US8758399B2 (en) 2010-08-02 2014-06-24 Abbott Cardiovascular Systems, Inc. Expandable bioabsorbable plug apparatus and method
US8784447B2 (en) 2000-09-08 2014-07-22 Abbott Vascular Inc. Surgical stapler
US8808310B2 (en) 2006-04-20 2014-08-19 Integrated Vascular Systems, Inc. Resettable clip applier and reset tools
US8820602B2 (en) 2007-12-18 2014-09-02 Abbott Laboratories Modular clip applier
US8821534B2 (en) 2010-12-06 2014-09-02 Integrated Vascular Systems, Inc. Clip applier having improved hemostasis and methods of use
US20140277114A1 (en) * 2013-03-15 2014-09-18 Essential Medical, Inc. Vascular closure device with occlusion balloon guidewire
US8858594B2 (en) 2008-12-22 2014-10-14 Abbott Laboratories Curved closure device
US8893947B2 (en) 2007-12-17 2014-11-25 Abbott Laboratories Clip applier and methods of use
US8905937B2 (en) 2009-02-26 2014-12-09 Integrated Vascular Systems, Inc. Methods and apparatus for locating a surface of a body lumen
US8920442B2 (en) 2005-08-24 2014-12-30 Abbott Vascular Inc. Vascular opening edge eversion methods and apparatuses
US8926633B2 (en) 2005-06-24 2015-01-06 Abbott Laboratories Apparatus and method for delivering a closure element
US8926656B2 (en) 2003-01-30 2015-01-06 Integated Vascular Systems, Inc. Clip applier and methods of use
US20150068009A1 (en) * 2010-06-08 2015-03-12 Essential Medical Llc Deployment instrument for closure device for percutaneously sealing punctures
US20150100083A1 (en) * 2011-10-25 2015-04-09 Essential Medical, Inc. Surgically closing percutaneously punctures
US9089311B2 (en) 2009-01-09 2015-07-28 Abbott Vascular Inc. Vessel closure devices and methods
US9089674B2 (en) 2000-10-06 2015-07-28 Integrated Vascular Systems, Inc. Apparatus and methods for positioning a vascular sheath
US9138214B2 (en) 2012-03-02 2015-09-22 Abbott Cardiovascular Systems, Inc. Suture securing systems, devices and methods
US9149265B2 (en) 2011-02-26 2015-10-06 Abbott Cardiovascular Systems, Inc. Hinged tissue support device
US9149276B2 (en) 2011-03-21 2015-10-06 Abbott Cardiovascular Systems, Inc. Clip and deployment apparatus for tissue closure
US9155530B2 (en) 2010-11-09 2015-10-13 Transluminal Technologies, Llc Specially designed magnesium-aluminum alloys and medical uses thereof in a hemodynamic environment
US9173644B2 (en) 2009-01-09 2015-11-03 Abbott Vascular Inc. Closure devices, systems, and methods
US9241706B2 (en) 2003-09-15 2016-01-26 Abbott Laboratories Suture locking device and methods
US9282965B2 (en) 2008-05-16 2016-03-15 Abbott Laboratories Apparatus and methods for engaging tissue
US9301746B2 (en) 2013-10-11 2016-04-05 Abbott Cardiovascular Systems, Inc. Suture-based closure with hemostatic tract plug
US9314230B2 (en) 2009-01-09 2016-04-19 Abbott Vascular Inc. Closure device with rapidly eroding anchor
US9332976B2 (en) 2011-11-30 2016-05-10 Abbott Cardiovascular Systems, Inc. Tissue closure device
US9364209B2 (en) 2012-12-21 2016-06-14 Abbott Cardiovascular Systems, Inc. Articulating suturing device
US9414820B2 (en) 2009-01-09 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US9414824B2 (en) 2009-01-16 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US9456811B2 (en) 2005-08-24 2016-10-04 Abbott Vascular Inc. Vascular closure methods and apparatuses
US9456816B2 (en) 2007-09-12 2016-10-04 Transluminal Technologies, Llc Closure device, deployment apparatus, and method of deploying a closure device
US9486191B2 (en) 2009-01-09 2016-11-08 Abbott Vascular, Inc. Closure devices
US9579091B2 (en) 2000-01-05 2017-02-28 Integrated Vascular Systems, Inc. Closure system and methods of use
US9585647B2 (en) 2009-08-26 2017-03-07 Abbott Laboratories Medical device for repairing a fistula
US9757106B2 (en) 2012-12-03 2017-09-12 Cook Medical Technologies Llc Degradable expanding closure plug
US9861410B2 (en) 2016-05-06 2018-01-09 Medos International Sarl Methods, devices, and systems for blood flow

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9642605B2 (en) * 2013-03-15 2017-05-09 Cook Medical Technologies Llc Vascular closure device suture tension limiting and indication mechanism

Citations (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US31855A (en) * 1861-03-26 G Weiland Straw-carrier for threshing-machines
US1088393A (en) * 1913-09-20 1914-02-24 Oscar E Backus Button.
US1331401A (en) * 1919-09-12 1920-02-17 Summers Henry Clay Button-fastening
US1480935A (en) * 1922-04-03 1924-01-15 Dora P Gleason Barrette
US2583625A (en) * 1946-10-29 1952-01-29 Thomas & Betts Corp Method of and tool for crimping tubes
US2969887A (en) * 1959-04-08 1961-01-31 American Thermos Products Comp Threaded pouring lip stopper combination for vacuum bottle
US3015403A (en) * 1959-04-08 1962-01-02 American Thermos Products Comp Threaded stopper expanding pouring lip combination for vacuum bottle
US3120230A (en) * 1960-10-24 1964-02-04 Jack H Sanders Surgical clamp
US3494533A (en) * 1966-10-10 1970-02-10 United States Surgical Corp Surgical stapler for stitching body organs
US3939820A (en) * 1974-10-29 1976-02-24 Datascope Corporation Single-chamber, multi-section balloon for cardiac assistance
US4189808A (en) * 1978-09-20 1980-02-26 Brown Theodore G Retainer and closure for a garbage can liner bag
US4368736A (en) * 1980-11-17 1983-01-18 Kaster Robert L Anastomotic fitting
US4428376A (en) * 1980-05-02 1984-01-31 Ethicon Inc. Plastic surgical staple
US4635634A (en) * 1985-07-12 1987-01-13 Santos Manuel V Surgical clip applicator system
US4719917A (en) * 1987-02-17 1988-01-19 Minnesota Mining And Manufacturing Company Surgical staple
US4724840A (en) * 1982-02-03 1988-02-16 Ethicon, Inc. Surgical fastener applier with rotatable front housing and laterally extending curved needle for guiding a flexible pusher
US4890612A (en) * 1987-02-17 1990-01-02 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
US4902508A (en) * 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US4983176A (en) * 1989-03-06 1991-01-08 University Of New Mexico Deformable plastic surgical clip
US5078731A (en) * 1990-06-05 1992-01-07 Hayhurst John O Suture clip
US5176648A (en) * 1991-12-13 1993-01-05 Unisurge, Inc. Introducer assembly and instrument for use therewith
US5275616A (en) * 1990-10-01 1994-01-04 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5281422A (en) * 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US5282808A (en) * 1992-05-26 1994-02-01 Origin Medsystems, Inc. Closure prevention apparatus for surgical clip applier
US5282827A (en) * 1991-11-08 1994-02-01 Kensey Nash Corporation Hemostatic puncture closure system and method of use
EP0621032A1 (en) * 1993-04-23 1994-10-26 Ciba-Geigy Ag Controlled release drug delivery device
US5383897A (en) * 1992-10-19 1995-01-24 Shadyside Hospital Method and apparatus for closing blood vessel punctures
US5383896A (en) * 1993-05-25 1995-01-24 Gershony; Gary Vascular sealing device
US5392978A (en) * 1991-02-08 1995-02-28 United States Surgical Corporation Surgical staple and endoscopic stapler
US5486195A (en) * 1993-07-26 1996-01-23 Myers; Gene Method and apparatus for arteriotomy closure
US5510115A (en) * 1987-11-16 1996-04-23 Baxter Travenol Laboratories, Inc. Method and composition for administration of beneficial agent by controlled dissolution
US5593412A (en) * 1994-03-01 1997-01-14 Cordis Corporation Stent delivery method and apparatus
US5709224A (en) * 1995-06-07 1998-01-20 Radiotherapeutics Corporation Method and device for permanent vessel occlusion
US5713899A (en) * 1995-04-27 1998-02-03 Societe Jbs Sa Cervical cage designed for the performance of intersomatic arthrodesis
US5720755A (en) * 1995-01-18 1998-02-24 Dakov; Pepi Tubular suturing device and methods of use
US5855312A (en) * 1996-07-25 1999-01-05 Toledano; Haviv Flexible annular stapler for closed surgery of hollow organs
US5858082A (en) * 1997-09-15 1999-01-12 Cruz; Hector Gonzalo Self-interlocking reinforcement fibers
US5860991A (en) * 1992-12-10 1999-01-19 Perclose, Inc. Method for the percutaneous suturing of a vascular puncture site
US5861005A (en) * 1997-02-11 1999-01-19 X-Site, L.L.C. Arterial stapling device
US5861003A (en) * 1996-10-23 1999-01-19 The Cleveland Clinic Foundation Apparatus and method for occluding a defect or aperture within body surface
US5868755A (en) * 1997-01-16 1999-02-09 Atrion Medical Products, Inc. Sheath retractor mechanism and method
US5868763A (en) * 1996-09-16 1999-02-09 Guidant Corporation Means and methods for performing an anastomosis
US5871474A (en) * 1995-05-19 1999-02-16 General Surgical Innovations, Inc. Screw-type skin seal with inflatable membrane
US5871525A (en) * 1992-04-13 1999-02-16 Ep Technologies, Inc. Steerable ablation catheter system
US5871501A (en) * 1994-01-18 1999-02-16 Datascope Investment Corp. Guide wire with releasable barb anchor
US5873876A (en) * 1996-09-23 1999-02-23 Christy; William J. Surgical loop delivery device and method
US6010517A (en) * 1996-04-10 2000-01-04 Baccaro; Jorge Alberto Device for occluding abnormal vessel communications
US6013084A (en) * 1995-06-30 2000-01-11 Target Therapeutics, Inc. Stretch resistant vaso-occlusive coils (II)
US6015815A (en) * 1997-09-26 2000-01-18 Abbott Laboratories Tetrazole-containing rapamycin analogs with shortened half-lives
US6024750A (en) * 1997-08-14 2000-02-15 United States Surgical Ultrasonic curved blade
US6024756A (en) * 1996-03-22 2000-02-15 Scimed Life Systems, Inc. Method of reversibly closing a septal defect
US6030364A (en) * 1997-10-03 2000-02-29 Boston Scientific Corporation Apparatus and method for percutaneous placement of gastro-intestinal tubes
US6030413A (en) * 1983-12-09 2000-02-29 Endovascular Technologies, Inc. Artificial graft and implantation method
US6171329B1 (en) * 1994-12-19 2001-01-09 Gore Enterprise Holdings, Inc. Self-expanding defect closure device and method of making and using
US6171277B1 (en) * 1997-12-01 2001-01-09 Cordis Webster, Inc. Bi-directional control handle for steerable catheter
US6174322B1 (en) * 1997-08-08 2001-01-16 Cardia, Inc. Occlusion device for the closure of a physical anomaly such as a vascular aperture or an aperture in a septum
US6179849B1 (en) * 1999-06-10 2001-01-30 Vascular Innovations, Inc. Sutureless closure for connecting a bypass graft to a target vessel
US6193708B1 (en) * 1997-08-05 2001-02-27 Scimed Life Systems, Inc. Detachable aneurysm neck bridge (I)
US6193734B1 (en) * 1998-01-23 2001-02-27 Heartport, Inc. System for performing vascular anastomoses
US6238705B1 (en) * 1995-07-28 2001-05-29 Advanced Poymer Systems, Inc. Bioerodible porous compositions
US6334865B1 (en) * 1998-08-04 2002-01-01 Fusion Medical Technologies, Inc. Percutaneous tissue track closure assembly and method
US6348064B1 (en) * 2000-09-01 2002-02-19 Angiolink Corporation Wound site management and wound closure device
US20020022822A1 (en) * 2000-07-14 2002-02-21 Cragg Andrew H. Sheath-mounted arterial plug delivery device
US20020026216A1 (en) * 1999-10-13 2002-02-28 Grimes Randall Y. Devices and methods for percutaneous mitral valve repair
US6455053B1 (en) * 1997-10-09 2002-09-24 Ssp Co., Ltd. Quickly soluble solid preparations
US6508828B1 (en) * 2000-11-03 2003-01-21 Radi Medical Systems Ab Sealing device and wound closure device
US6514280B1 (en) * 1998-04-02 2003-02-04 Salviac Limited Delivery catheter
US6517555B1 (en) * 2000-09-05 2003-02-11 Clear Sight, Inc. Method for treating presbyopia
US6517569B2 (en) * 1998-09-14 2003-02-11 Endocare, Inc. Insertion device for stents and methods for use
US6676685B2 (en) * 1999-02-22 2004-01-13 Tyco Healthcare Group Lp Arterial hole closure apparatus
US6676671B2 (en) * 1998-09-15 2004-01-13 United States Surgical Stapling apparatus and method for heart valve replacement
US6679904B2 (en) * 1996-10-17 2004-01-20 Malachy Gleeson Device for closure of puncture wound
US6689147B1 (en) * 2000-06-13 2004-02-10 J. Kenneth Koster, Jr. Anastomosis punch device and method
US6695867B2 (en) * 2002-02-21 2004-02-24 Integrated Vascular Systems, Inc. Plunger apparatus and methods for delivering a closure device
US6837893B2 (en) * 2000-09-01 2005-01-04 Onux Medical, Inc. Multi-fastener surgical apparatus and method
US6837906B2 (en) * 2001-08-03 2005-01-04 Ensure Medical, Inc. Lung assist apparatus and methods for use
US6846319B2 (en) * 2000-12-14 2005-01-25 Core Medical, Inc. Devices for sealing openings through tissue and apparatus and methods for delivering them
US6849078B2 (en) * 1999-11-18 2005-02-01 Ovesco Endoscopy, Gmbh Apparatus and method for compressing body tissue
US20050152949A1 (en) * 2004-01-13 2005-07-14 Orthobiologica, Inc. Drug delivery to a joint
US20050169974A1 (en) * 2002-05-08 2005-08-04 Radi Medical Systems Ab Dissolvable medical sealing device
US6984238B2 (en) * 1995-02-24 2006-01-10 Gifford Iii Hanson S Devices and methods for performing avascular anastomosis
US6989016B2 (en) * 1998-07-22 2006-01-24 Medtronic Angiolink, Inc. Vascular suction cannula, dilator and surgical stapler
US6989003B2 (en) * 2001-08-31 2006-01-24 Conmed Corporation Obturator and cannula for a trocar adapted for ease of insertion and removal
US7001400B1 (en) * 1999-03-04 2006-02-21 Abbott Laboratories Articulating suturing device and method
US7001398B2 (en) * 2000-12-07 2006-02-21 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US20060047313A1 (en) * 2004-08-27 2006-03-02 Accessclosure, Inc. Apparatus and methods for facilitating hemostasis within a vascular puncture
US7163551B2 (en) * 2001-08-09 2007-01-16 Thomas Anthony Surgical stapling device
US7169158B2 (en) * 1996-07-23 2007-01-30 Tyco Healthcare Group Lp Anastomosis instrument and method for performing same
US7169164B2 (en) * 2000-09-21 2007-01-30 Atritech, Inc. Apparatus for implanting devices in atrial appendages
US20070027525A1 (en) * 2003-11-19 2007-02-01 Neovasc Medical Ltd Vascular implant
US20070027476A1 (en) * 2005-02-07 2007-02-01 Regen Biologics, Inc. System and method for all-inside suture fixation for implant attachment and soft tissue repair
US20070172430A1 (en) * 2006-01-20 2007-07-26 Nastech Pharmaceutical Company Inc. Dry powder compositions for rna influenza therapeutics
US20070275036A1 (en) * 2006-05-18 2007-11-29 Celldyne Biopharma, Llc Avian follistatin product
US20070282373A1 (en) * 2003-11-25 2007-12-06 Mark Ashby Hemostatic Pressure Plug
US7316704B2 (en) * 2003-06-04 2008-01-08 Accessclosure, Inc. Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture
US7322995B2 (en) * 2002-09-13 2008-01-29 Damage Control Surgical Technologies, Inc. Method and apparatus for vascular and visceral clipping
US7326230B2 (en) * 2003-10-23 2008-02-05 Sundaram Ravikumar Vascular sealing device and method of use
US7335220B2 (en) * 2004-11-05 2008-02-26 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
US20080114395A1 (en) * 2005-01-14 2008-05-15 Radi Medical Systems Ab Closure Device
US20090171388A1 (en) * 2007-10-31 2009-07-02 Vipul Bhupendra Dave Vascular closure device
US20090216267A1 (en) * 2008-02-26 2009-08-27 Boston Scientific Scimed, Inc. Closure device with rapidly dissolving anchor
US20090227938A1 (en) * 2008-03-05 2009-09-10 Insitu Therapeutics, Inc. Wound Closure Devices, Methods of Use, and Kits
US7645285B2 (en) * 2004-05-26 2010-01-12 Idx Medical, Ltd Apparatus and methods for occluding a hollow anatomical structure
US20100042144A1 (en) * 2008-08-12 2010-02-18 Steven Bennett Medical Device for Wound Closure and Method of Use
US20130006274A1 (en) * 2005-07-01 2013-01-03 Abbott Laboratories Clip applier and methods of use
US20140005692A1 (en) * 2003-01-30 2014-01-02 Integrated Vascular Systems, Inc. Methods of use of a clip applier
US20140018850A1 (en) * 2006-06-28 2014-01-16 Abbott Laboratories Vessel closure device

Family Cites Families (762)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US438400A (en) 1890-10-14 Connector for electric conductors
US287046A (en) 1883-10-23 Combined cork and screw nozzle
US556082A (en) 1896-03-10 Julius boeddinghaus
US1123290A (en) 1914-05-12 1915-01-05 Otto Von Herff Surgical clip.
US1596004A (en) 1923-04-04 1926-08-17 Bengoa Miguel Becerro De Hypodermic syringe
US1647958A (en) 1926-11-02 1927-11-01 Ariberto E Ciarlante Hair-curling material and method of preparing the same
US1880569A (en) 1930-09-27 1932-10-04 John P Weis Surgical clip applying instrument
US2087074A (en) 1936-08-17 1937-07-13 Tucker Ralph Button
US2210061A (en) 1939-01-24 1940-08-06 Aircraft Screw Prod Co Inserting tool
US2254620A (en) 1939-11-14 1941-09-02 George I Miller Clip
US2371978A (en) 1941-12-13 1945-03-20 Roy G Perham Clamp for retaining the edges of a wound in apposition
US2316297A (en) 1943-01-15 1943-04-13 Beverly A Southerland Surgical instrument
US2453227A (en) 1946-09-21 1948-11-09 George Martin Button staple anchor and shield
US2910067A (en) 1952-10-13 1959-10-27 Technical Oil Tool Corp Wound clip and extractor therefor
US2684070A (en) 1953-03-23 1954-07-20 Walter L Kelsey Surgical clip
US2755699A (en) 1953-07-16 1956-07-24 Heli Coil Corp Wire coil screw thread insert with grip end having an angular configuration
US2951482A (en) 1955-09-22 1960-09-06 Gregory B Sullivan Surgical saw
US3113379A (en) 1956-02-28 1963-12-10 Joseph J Frank Closure fastening
US2944311A (en) 1956-10-20 1960-07-12 Schneckenberger Adolf Detachable fastening device
US3209754A (en) 1961-08-10 1965-10-05 Ernest C Wood Surgical clip
US3142878A (en) 1963-04-10 1964-08-04 James V Santora Staple button fastener
US3482428A (en) 1967-07-12 1969-12-09 Nikolai Nikolaevich Kapitanov Surgical apparatus for suturing tissues with metal staples
US3523351A (en) 1967-10-20 1970-08-11 Sargent & Co Locator and holder in a crimping tool for an electrical connector
US3586002A (en) 1968-01-08 1971-06-22 Ernest C Wood Surgical skin clip
US3510923A (en) 1968-06-20 1970-05-12 American Hospital Supply Corp Parallel jaw ratchet clip and retractor
US3604425A (en) 1969-04-11 1971-09-14 New Research And Dev Lab Inc Hemostatic clip
US3618447A (en) 1969-09-15 1971-11-09 Phillips Petroleum Co Deterioration fasteners
US3985138A (en) 1972-08-25 1976-10-12 Jarvik Robert K Preformed ligatures for bleeders and methods of applying such ligatures
US3757629A (en) 1971-05-10 1973-09-11 R Schneider Resilient plastic staple
BE789131A (en) 1971-09-24 1973-03-22 Extracorporeal Med Spec surgical needle for performing medical operations
US3856016A (en) 1972-11-03 1974-12-24 H Davis Method for mechanically applying an occlusion clip to an anatomical tubular structure
US3823719A (en) 1972-11-14 1974-07-16 Acme United Corp Finger operated forceps type surgical instrument
GB1358466A (en) 1972-11-22 1974-07-03 Vnii Ispytatel Med Tech Surgical instrument for stitching tissue with suture wire
US3874388A (en) 1973-02-12 1975-04-01 Ochsner Med Found Alton Shunt defect closure system
US3828791A (en) 1973-03-21 1974-08-13 M Santos Surgical instruments
US3805337A (en) 1973-04-23 1974-04-23 Raymond Lee Organization Inc Spring wire hose clamp
GB1413191A (en) 1973-07-04 1975-11-12 Vnii Khirurgicheskoi Apparatur Device for the eversion of hollow organs and vascular stapling instrument incorporating same
NL7403762A (en) 1974-03-20 1975-09-23 Leer Koninklijke Emballage Plug of plastics or the like material, provided with external screw thread.
US3926194A (en) 1974-11-20 1975-12-16 Ethicon Inc Sutures with reduced diameter at suture tip
US4018228A (en) 1975-02-24 1977-04-19 Goosen Carl C Surgical punch apparatus
US3960147A (en) 1975-03-10 1976-06-01 Murray William M Compression bone staples and methods of compressing bone segments
GB1486351A (en) 1975-06-06 1977-09-21 Rocket Of London Ltd Surgical clip applicator
US4014492A (en) 1975-06-11 1977-03-29 Senco Products, Inc. Surgical staple
US4007743A (en) 1975-10-20 1977-02-15 American Hospital Supply Corporation Opening mechanism for umbrella-like intravascular shunt defect closure device
GB1526186A (en) 1976-04-28 1978-09-27 Kendall & Co Device for testing whether a tip of a hollow needle inserted in a patient's body is in a region of sub-or supra-atmospheric pressure
DE2730691C2 (en) 1976-07-16 1982-12-16 Maruho Co. Ltd., Osaka, Jp
US4047533A (en) 1976-09-20 1977-09-13 American Cyanamid Company Absorbable surgical sutures coated with polyoxyethylene-polyoxypropylene copolymer lubricant
US4112944A (en) 1976-12-13 1978-09-12 Williams Gayland M Tube clamp and piercing device
DE2658478C2 (en) 1976-12-23 1978-11-30 Aesculap-Werke Ag Vormals Jetter & Scheerer, 7200 Tuttlingen
US4204541A (en) 1977-01-24 1980-05-27 Kapitanov Nikolai N Surgical instrument for stitching up soft tissues with lengths of spiked suture material
US4153321A (en) 1977-03-17 1979-05-08 Kravex Manufacturing Company Battery booster cable
US4217902A (en) 1977-05-02 1980-08-19 March Alfred L Hemostatic clip
US4169476A (en) 1977-08-12 1979-10-02 Wolf Medical Instruments Corporation Applicator for surgical clip
US4201215A (en) 1977-09-06 1980-05-06 Crossett E S Apparatus and method for closing a severed sternum
US4345606A (en) 1977-12-13 1982-08-24 Littleford Philip O Split sleeve introducers for pacemaker electrodes and the like
US4215699A (en) 1978-04-03 1980-08-05 The Kendall Company Position indicating device
US4207870A (en) 1978-06-15 1980-06-17 Becton, Dickinson And Company Blood sampling assembly having porous vent means vein entry indicator
US4273129A (en) 1978-06-29 1981-06-16 Richard Wolf Gmbh Forceps for applying clips to fallopian tubes
USRE31855F1 (en) 1978-12-01 1986-08-19 Tear apart cannula
US4355751A (en) 1978-12-08 1982-10-26 Kapitanov Nikolai N Surgical instrument for suturing cutaneous tissue
US4214587A (en) 1979-02-12 1980-07-29 Sakura Chester Y Jr Anastomosis device and method
US4440170A (en) 1979-03-06 1984-04-03 Ethicon, Inc. Surgical clip applying instrument
US4278091A (en) 1980-02-01 1981-07-14 Howmedica, Inc. Soft tissue retainer for use with bone implants, especially bone staples
US4396139A (en) 1980-02-15 1983-08-02 Technalytics, Inc. Surgical stapling system, apparatus and staple
US4317451A (en) 1980-02-19 1982-03-02 Ethicon, Inc. Plastic surgical staple
US4317445A (en) 1980-03-31 1982-03-02 Baxter Travenol Laboratories, Inc. Catheter insertion unit with separate flashback indication for the cannula
US4318401A (en) 1980-04-24 1982-03-09 President And Fellows Of Harvard College Percutaneous vascular access portal and catheter
FR2481594B1 (en) 1980-05-02 1985-01-04 Ethicon Inc
US4327485A (en) 1980-05-21 1982-05-04 Amp Incorporated Pistol grip tool
US4407286A (en) 1980-08-25 1983-10-04 United States Surgical Corporation Surgical staples
US4505274A (en) 1980-10-17 1985-03-19 Propper Manufacturing Co., Inc. Suture clip
US4526174A (en) 1981-03-27 1985-07-02 Minnesota Mining And Manufacturing Company Staple and cartridge for use in a tissue stapling device and a tissue closing method
US4411654A (en) 1981-04-30 1983-10-25 Baxter Travenol Laboratories, Inc. Peelable catheter with securing ring and suture sleeve
US4412832A (en) 1981-04-30 1983-11-01 Baxter Travenol Laboratories, Inc. Peelable catheter introduction device
US4485816A (en) 1981-06-25 1984-12-04 Alchemia Shape-memory surgical staple apparatus and method for use in surgical suturing
US4449531A (en) 1981-08-27 1984-05-22 Ethicon, Inc. Non-metallic, bio-compatible hemostatic clips with interlocking latch means
US4570633A (en) 1981-09-28 1986-02-18 Ethicon, Inc. Surgical clip applier instrument adapter jaws
US4480356A (en) 1981-10-07 1984-11-06 Martin Donald A Double-grip clip
DE3204522C2 (en) 1982-02-10 1988-08-25 B. Braun Melsungen Ag, 3508 Melsungen, De
DE3204532C2 (en) 1982-02-10 1983-12-08 B. Braun Melsungen Ag, 3508 Melsungen, De
US4475544A (en) 1982-02-23 1984-10-09 Reis Norman I Bone gripping forceps
US4860746A (en) 1982-04-20 1989-08-29 Inbae Yoon Elastic surgical ring clip and ring loader
US4664305A (en) 1982-05-04 1987-05-12 Blake Joseph W Iii Surgical stapler
JPS58181006U (en) 1982-05-28 1983-12-03
US4934364A (en) 1982-09-30 1990-06-19 United States Surgical Corporation Surgical clip applying apparatus having fixed jams
US4523591A (en) 1982-10-22 1985-06-18 Kaplan Donald S Polymers for injection molding of absorbable surgical devices
US4525157A (en) 1983-07-28 1985-06-25 Manresa, Inc. Closed system catheter with guide wire
EP0137500B1 (en) 1983-10-13 1988-09-14 Jürgen Prof. Dr. Morgenstern Physiological sensor
US4665906A (en) 1983-10-14 1987-05-19 Raychem Corporation Medical devices incorporating sim alloy elements
US4929240A (en) 1983-12-01 1990-05-29 University Of New Mexico Surgical clip and applier
US4586503A (en) 1983-12-01 1986-05-06 University Of New Mexico Surgical microclip
US6221102B1 (en) 1983-12-09 2001-04-24 Endovascular Technologies, Inc. Intraluminal grafting system
US4917087A (en) 1984-04-10 1990-04-17 Walsh Manufacturing (Mississuaga) Limited Anastomosis devices, kits and method
US4607638A (en) 1984-04-20 1986-08-26 Design Standards Corporation Surgical staples
DE3420455C1 (en) 1984-06-01 1985-05-15 Peter Dr-Ing Osypka Separating means for Einfuehrungshuelse
US4610252A (en) 1984-10-15 1986-09-09 Catalano J Denis Dual muscle clamp
US4651737A (en) 1984-10-15 1987-03-24 American Cyanamid Company Nonmetallic surgical clip
US4596559A (en) 1984-11-02 1986-06-24 Fleischhacker John J Break-away handle for a catheter introducer set
US4610251A (en) 1985-04-19 1986-09-09 Kumar Sarbjeet S Surgical staple
CN85106639B (en) 1985-09-03 1988-08-03 第三军医大学野战外科研究所 Instrument for blood vessel anastomosis
DE3533423C2 (en) 1985-09-19 1990-02-22 Richard Wolf Gmbh, 7134 Knittlingen, De
US4834757A (en) 1987-01-22 1989-05-30 Brantigan John W Prosthetic implant
US4693249A (en) 1986-01-10 1987-09-15 Schenck Robert R Anastomosis device and method
JPH0522551B2 (en) 1986-04-09 1993-03-29 Terumo Corp
US4777950A (en) 1986-04-11 1988-10-18 Kees Surgical Specialty Co. Vascular clip
US4967949A (en) 1986-07-11 1990-11-06 Vastech Medical Products Inc. Apparatus for effecting occlusion of the vas deferens
US4874122A (en) 1986-07-14 1989-10-17 Minnesota Mining And Manufacturing Company Bent back box staple and staple closing mechanism with split actuator
US4738658A (en) 1986-09-19 1988-04-19 Aries Medical Incorporated Tapered hemostatic device for use in conjunction with a catheter for alleviating blood leakage and method for using same
US4789090A (en) 1986-11-03 1988-12-06 Blake Joseph W Iii Surgical stapler
US4771782A (en) 1986-11-14 1988-09-20 Millar Instruments, Inc. Method and assembly for introducing multiple catheters into a biological vessel
US4852568A (en) 1987-02-17 1989-08-01 Kensey Nash Corporation Method and apparatus for sealing an opening in tissue of a living being
US4744364A (en) 1987-02-17 1988-05-17 Intravascular Surgical Instruments, Inc. Device for sealing percutaneous puncture in a vessel
USRE34866E (en) 1987-02-17 1995-02-21 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
US4865026A (en) 1987-04-23 1989-09-12 Barrett David M Sealing wound closure device
US4772266A (en) 1987-05-04 1988-09-20 Catheter Technology Corp. Catheter dilator/sheath assembly and method
US5366459A (en) 1987-05-14 1994-11-22 Inbae Yoon Surgical clip and clip application procedures
US5478353A (en) 1987-05-14 1995-12-26 Yoon; Inbae Suture tie device system and method for suturing anatomical tissue proximate an opening
US5171250A (en) 1987-05-14 1992-12-15 Inbae Yoon Surgical clips and surgical clip applicator and cutting and transection device
US5100418A (en) 1987-05-14 1992-03-31 Inbae Yoon Suture tie device system and applicator therefor
US5011487A (en) 1987-06-24 1991-04-30 United States Surgical Corporation Vascular clamp assembly
US4836204A (en) 1987-07-06 1989-06-06 Landymore Roderick W Method for effecting closure of a perforation in the septum of the heart
JPH0579336B2 (en) 1987-07-14 1993-11-02 Bikutoru Arekuseebich Ripatofu
US4887601A (en) 1987-11-06 1989-12-19 Ophthalmic Ventures Limited Partnership Adjustable surgical staple and method of using the same
US5030226A (en) 1988-01-15 1991-07-09 United States Surgical Corporation Surgical clip applicator
JP2561853B2 (en) 1988-01-28 1996-12-11 株式会社ジェイ・エム・エス Compacts and methods of use thereof with a shape memory
US5114065A (en) 1988-05-23 1992-05-19 Technalytics, Inc. Surgical stapler
US5254105A (en) 1988-05-26 1993-10-19 Haaga John R Sheath for wound closure caused by a medical tubular device
US5330445A (en) 1988-05-26 1994-07-19 Haaga John R Sheath for wound closure caused by a medical tubular device
CA2004658C (en) 1988-06-03 1995-10-10 Michael A. Oberlander Arthroscopic clip and insertion tool
US5002562A (en) 1988-06-03 1991-03-26 Oberlander Michael A Surgical clip
US5015247A (en) 1988-06-13 1991-05-14 Michelson Gary K Threaded spinal implant
US4885003A (en) 1988-07-25 1989-12-05 Cordis Corporation Double mesh balloon catheter device
US4917089A (en) 1988-08-29 1990-04-17 Sideris Eleftherios B Buttoned device for the transvenous occlusion of intracardiac defects
CA2000360A1 (en) 1988-10-11 1990-04-11 Stephen J. Failla Ophthalmic staple and instruments for implementing use
US5047047A (en) 1988-10-26 1991-09-10 Inbae Yoon Wound closing device
US4961729A (en) 1988-12-13 1990-10-09 Vaillancourt Vincent L Catheter insertion assembly
US4976721A (en) 1988-12-14 1990-12-11 The Research Foundation Of State University Of New York Surgical clamping device
US4886067A (en) 1989-01-03 1989-12-12 C. R. Bard, Inc. Steerable guidewire with soft adjustable tip
FR2641692B1 (en) 1989-01-17 1995-05-12 Nippon Zeon Co
US4997439A (en) 1989-01-26 1991-03-05 Chen Fusen H Surgical closure or anastomotic device
JPH07103457B2 (en) 1989-02-10 1995-11-08 トミー株式会社 Form method of applying shape memory alloy orthodontic wire
US5053047A (en) 1989-05-16 1991-10-01 Inbae Yoon Suture devices particularly useful in endoscopic surgery and methods of suturing
US5100422A (en) 1989-05-26 1992-03-31 Impra, Inc. Blood vessel patch
US5620461A (en) 1989-05-29 1997-04-15 Muijs Van De Moer; Wouter M. Sealing device
US5007921A (en) 1989-10-26 1991-04-16 Brown Alan W Surgical staple
US5026390A (en) 1989-10-26 1991-06-25 Brown Alan W Surgical staple
US5059201A (en) 1989-11-03 1991-10-22 Asnis Stanley E Suture threading, stitching and wrapping device for use in open and closed surgical procedures
GB8924806D0 (en) 1989-11-03 1989-12-20 Neoligaments Ltd Prosthectic ligament system
US5122122A (en) 1989-11-22 1992-06-16 Dexide, Incorporated Locking trocar sleeve
WO1993007813A1 (en) 1989-12-04 1993-04-29 Kensey Nash Corporation Plug device for sealing openings and method of use
US5061274A (en) 1989-12-04 1991-10-29 Kensey Nash Corporation Plug device for sealing openings and method of use
US5797958A (en) 1989-12-05 1998-08-25 Yoon; Inbae Endoscopic grasping instrument with scissors
US5226908A (en) 1989-12-05 1993-07-13 Inbae Yoon Multi-functional instruments and stretchable ligating and occluding devices
GB8928196D0 (en) * 1989-12-13 1990-02-14 Merrell Dow Pharmaceuticals Li Pharmaceutical lozenges
US5421832A (en) 1989-12-13 1995-06-06 Lefebvre; Jean-Marie Filter-catheter and method of manufacturing same
US5156609A (en) 1989-12-26 1992-10-20 Nakao Naomi L Endoscopic stapling device and method
US5891088A (en) 1990-02-02 1999-04-06 Ep Technologies, Inc. Catheter steering assembly providing asymmetric left and right curve configurations
US5035692A (en) 1990-02-13 1991-07-30 Nicholas Herbert Hemostasis clip applicator
US5197971A (en) 1990-03-02 1993-03-30 Bonutti Peter M Arthroscopic retractor and method of using the same
US5032127A (en) 1990-03-07 1991-07-16 Frazee John G Hemostatic clip and applicator therefor
CA2057018C (en) 1990-04-02 1997-12-09 Kanji Inoue Device for nonoperatively occluding a defect
US5167643A (en) 1990-04-27 1992-12-01 Lynn Lawrence A Needle protection station
US5021059A (en) 1990-05-07 1991-06-04 Kensey Nash Corporation Plug device with pulley for sealing punctures in tissue and methods of use
DE4014653A1 (en) 1990-05-08 1991-11-14 Beiersdorf Ag surgical clamp
US5116349A (en) 1990-05-23 1992-05-26 United States Surgical Corporation Surgical fastener apparatus
US5193533A (en) 1990-07-09 1993-03-16 Brigham And Women's Hospital High-pressure jet ventilation catheter
US5391183A (en) 1990-09-21 1995-02-21 Datascope Investment Corp Device and method sealing puncture wounds
US7008439B1 (en) 1990-09-21 2006-03-07 Datascope Investments Corp. Device and method for sealing puncture wounds
US5192300A (en) 1990-10-01 1993-03-09 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
CA2027427A1 (en) 1990-10-12 1992-04-13 William S. Laidlaw Plug for sealing wood preservative in wood structures
US5042707A (en) 1990-10-16 1991-08-27 Taheri Syde A Intravascular stapler, and method of operating same
FR2668361B1 (en) 1990-10-30 1995-04-21 Christian Mai
US5053008A (en) 1990-11-21 1991-10-01 Sandeep Bajaj Intracardiac catheter
US5366458A (en) 1990-12-13 1994-11-22 United States Surgical Corporation Latchless surgical clip
US5122156A (en) 1990-12-14 1992-06-16 United States Surgical Corporation Apparatus for securement and attachment of body organs
US5425489A (en) 1990-12-20 1995-06-20 United States Surgical Corporation Fascia clip and instrument
CA2055985A1 (en) 1990-12-20 1992-06-21 Daniel Shichman Fascia clip
US5419765A (en) 1990-12-27 1995-05-30 Novoste Corporation Wound treating device and method for treating wounds
US5250058A (en) 1991-01-17 1993-10-05 Ethicon, Inc. Absorbable anastomosic fastener means
US5131379A (en) 1991-01-29 1992-07-21 Sewell Jr Frank K Device and method for inserting a cannula into a duct
US5108420A (en) 1991-02-01 1992-04-28 Temple University Aperture occlusion device
US5171249A (en) 1991-04-04 1992-12-15 Ethicon, Inc. Endoscopic multiple ligating clip applier
US5470010A (en) 1991-04-04 1995-11-28 Ethicon, Inc. Multiple fire endoscopic stapling mechanism
US5192602A (en) 1991-05-14 1993-03-09 Spencer Victor V Louvered filter and paint arrestor
US5243857A (en) 1991-06-14 1993-09-14 Molex Incorporated Fixture for testing electrical terminations
US5236435A (en) 1991-07-22 1993-08-17 Sewell Jr Frank Laparoscopic surgical staple system
US5167634A (en) 1991-08-22 1992-12-01 Datascope Investment Corp. Peelable sheath with hub connector
US5449359A (en) 1991-09-05 1995-09-12 Groiso; Jorge A. Elastic clip for osteosynthesis
US5246156A (en) 1991-09-12 1993-09-21 Ethicon, Inc. Multiple fire endoscopic stapling mechanism
CA2078530A1 (en) 1991-09-23 1993-03-24 Jay Erlebacher Percutaneous arterial puncture seal device and insertion tool therefore
US5289963A (en) 1991-10-18 1994-03-01 United States Surgical Corporation Apparatus and method for applying surgical staples to attach an object to body tissue
US5497933A (en) 1991-10-18 1996-03-12 United States Surgical Corporation Apparatus and method for applying surgical staples to attach an object to body tissue
US5141520A (en) 1991-10-29 1992-08-25 Marlowe Goble E Harpoon suture anchor
US5290310A (en) 1991-10-30 1994-03-01 Howmedica, Inc. Hemostatic implant introducer
EP0545091B1 (en) 1991-11-05 1999-07-07 The Children's Medical Center Corporation Occluder for repair of cardiac and vascular defects
US5676689A (en) 1991-11-08 1997-10-14 Kensey Nash Corporation Hemostatic puncture closure system including vessel location device and method of use
US5411520A (en) 1991-11-08 1995-05-02 Kensey Nash Corporation Hemostatic vessel puncture closure system utilizing a plug located within the puncture tract spaced from the vessel, and method of use
US5222974A (en) 1991-11-08 1993-06-29 Kensey Nash Corporation Hemostatic puncture closure system and method of use
US5242456A (en) 1991-11-21 1993-09-07 Kensey Nash Corporation Apparatus and methods for clamping tissue and reflecting the same
US6056768A (en) 1992-01-07 2000-05-02 Cates; Christopher U. Blood vessel sealing system
DE4200255A1 (en) 1992-01-08 1993-07-15 Sueddeutsche Feinmechanik Spaltkanuele and methods for producing such
US5433721A (en) 1992-01-17 1995-07-18 Ethicon, Inc. Endoscopic instrument having a torsionally stiff drive shaft for applying fasteners to tissue
JP3393383B2 (en) 1992-01-21 2003-04-07 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ Septal defect closure device
US5163343A (en) 1992-02-21 1992-11-17 Gish Donald A System for fastening plies of fabric
US5509900A (en) 1992-03-02 1996-04-23 Kirkman; Thomas R. Apparatus and method for retaining a catheter in a blood vessel in a fixed position
US6059825A (en) 1992-03-05 2000-05-09 Angiodynamics, Inc. Clot filter
CA2090980C (en) 1992-03-06 2004-11-30 David Stefanchik Ligating clip applier
WO1993018711A1 (en) 1992-03-18 1993-09-30 Izi Corporation Post-surgical gross pathology specimen marker
US5304183A (en) 1992-03-23 1994-04-19 Laparomed Corporation Tethered clamp retractor
US5217024A (en) 1992-03-27 1993-06-08 Dorsey Denis P Tissue sampling device with visual and tactile indicator
US5236440A (en) 1992-04-14 1993-08-17 American Cyanamid Company Surgical fastener
WO1993021844A1 (en) 1992-04-23 1993-11-11 Scimed Life Systems, Inc. Apparatus and method for sealing vascular punctures
US6063085A (en) 1992-04-23 2000-05-16 Scimed Life Systems, Inc. Apparatus and method for sealing vascular punctures
US5540712A (en) 1992-05-01 1996-07-30 Nitinol Medical Technologies, Inc. Stent and method and apparatus for forming and delivering the same
US5242457A (en) 1992-05-08 1993-09-07 Ethicon, Inc. Surgical instrument and staples for applying purse string sutures
DE4215449C1 (en) 1992-05-11 1993-09-02 Ethicon Gmbh & Co Kg, 2000 Norderstedt, De
US5766246A (en) 1992-05-20 1998-06-16 C. R. Bard, Inc. Implantable prosthesis and method and apparatus for loading and delivering an implantable prothesis
US5431667A (en) 1992-05-26 1995-07-11 Origin Medsystems, Inc. Gas-sealed instruments for use in laparoscopic surgery
US5269792A (en) 1992-05-26 1993-12-14 Origin Medsystems, Inc. Surgical clip
US5255679A (en) 1992-06-02 1993-10-26 Cardiac Pathways Corporation Endocardial catheter for mapping and/or ablation with an expandable basket structure having means for providing selective reinforcement and pressure sensing mechanism for use therewith, and method
JPH0647050A (en) 1992-06-04 1994-02-22 Olympus Optical Co Ltd Tissue suture and ligature device
US5797931A (en) 1992-06-04 1998-08-25 Olympus Optical Co., Ltd. Tissue-fixing surgical instrument, tissue-fixing device, and method of fixing tissues
US5484420A (en) 1992-07-09 1996-01-16 Wilson-Cook Medical Inc. Retention bolsters for percutaneous catheters
US5242459A (en) 1992-07-10 1993-09-07 Laparomed Corporation Device and method for applying a ligating loop
US5290243A (en) 1992-07-16 1994-03-01 Technalytics, Inc. Trocar system
US5413571A (en) 1992-07-16 1995-05-09 Sherwood Medical Company Device for sealing hemostatic incisions
US5292332A (en) 1992-07-27 1994-03-08 Lee Benjamin I Methods and device for percutanceous sealing of arterial puncture sites
US5443481A (en) 1992-07-27 1995-08-22 Lee; Benjamin I. Methods and device for percutaneous sealing of arterial puncture sites
US5334199A (en) 1992-08-17 1994-08-02 Inbae Yoon Ligating instrument and methods of ligating tissue in endoscopic operative procedures
US5342393A (en) 1992-08-27 1994-08-30 Duke University Method and device for vascular repair
US5364408A (en) 1992-09-04 1994-11-15 Laurus Medical Corporation Endoscopic suture system
US5471982A (en) 1992-09-29 1995-12-05 Ep Technologies, Inc. Cardiac mapping and ablation systems
US5306254A (en) 1992-10-01 1994-04-26 Kensey Nash Corporation Vessel position locating device and method of use
US5304184A (en) 1992-10-19 1994-04-19 Indiana University Foundation Apparatus and method for positive closure of an internal tissue membrane opening
DE4235506A1 (en) 1992-10-21 1994-04-28 Bavaria Med Tech Catheter for injection of drugs
US5309927A (en) 1992-10-22 1994-05-10 Ethicon, Inc. Circular stapler tissue retention spring method
US5676974A (en) 1992-10-23 1997-10-14 Santiago H. Valdes Pharmaceutical compositions containing giroxina and phospholipase A2 and methods of increasing a patient's CD4 count using the pharmaceutical compositions
US5344439A (en) 1992-10-30 1994-09-06 Medtronic, Inc. Catheter with retractable anchor mechanism
FR2700464B1 (en) 1992-11-13 1995-04-14 Maurice Bertholet connecting piece for bony elements.
US5972000A (en) 1992-11-13 1999-10-26 Influence Medical Technologies, Ltd. Non-linear anchor inserter device and bone anchors
US5522840A (en) 1992-11-23 1996-06-04 Krajicek; Milan Device for the non-surgical seal of the interstice in the wall of a vessel
US5334216A (en) 1992-12-10 1994-08-02 Howmedica Inc. Hemostatic plug
US5284488A (en) 1992-12-23 1994-02-08 Sideris Eleftherios B Adjustable devices for the occlusion of cardiac defects
US5327908A (en) 1993-01-08 1994-07-12 United States Surgical Corporation Surgical apparatus for measuring body tissue
US5292309A (en) 1993-01-22 1994-03-08 Schneider (Usa) Inc. Surgical depth measuring instrument and method
US5304204A (en) 1993-02-09 1994-04-19 Ethicon, Inc. Receiverless surgical fasteners
US5797960A (en) 1993-02-22 1998-08-25 Stevens; John H. Method and apparatus for thoracoscopic intracardiac procedures
US5425705A (en) 1993-02-22 1995-06-20 Stanford Surgical Technologies, Inc. Thoracoscopic devices and methods for arresting the heart
US5814058A (en) 1993-03-05 1998-09-29 Innerdyne, Inc. Method and apparatus employing conformable sleeve for providing percutaneous access
US5320639A (en) 1993-03-12 1994-06-14 Meadox Medicals, Inc. Vascular plug delivery system
US5456400A (en) 1993-04-22 1995-10-10 United States Surgical Corporation Apparatus and clip for fastening body tissue
US5843167A (en) 1993-04-22 1998-12-01 C. R. Bard, Inc. Method and apparatus for recapture of hooked endoprosthesis
FR2704132B1 (en) 1993-04-23 1995-07-13 Ethnor System ligation and / or suture for endoscopic surgery.
US5335680A (en) 1993-04-26 1994-08-09 Moore Pamela K Hair clip
US5447265A (en) 1993-04-30 1995-09-05 Minnesota Mining And Manufacturing Company Laparoscopic surgical instrument with a mechanism for preventing its entry into the abdominal cavity once it is depleted and removed from the abdominal cavity
US5352229A (en) 1993-05-12 1994-10-04 Marlowe Goble E Arbor press staple and washer and method for its use
US5478354A (en) 1993-07-14 1995-12-26 United States Surgical Corporation Wound closing apparatus and method
US5507755A (en) 1993-08-03 1996-04-16 Origin Medsystems, Inc. Apparatus and method for closing puncture wounds
US5462561A (en) 1993-08-05 1995-10-31 Voda; Jan K. Suture device
US5431639A (en) 1993-08-12 1995-07-11 Boston Scientific Corporation Treating wounds caused by medical procedures
US5830125A (en) 1993-08-12 1998-11-03 Scribner-Browne Medical Design Incorporated Catheter introducer with suture capability
FR2710254B1 (en) 1993-09-21 1995-10-27 Mai Christian Clip multi-branches autorétentive dynamic compression osteosynthesis.
US5725554A (en) 1993-10-08 1998-03-10 Richard-Allan Medical Industries, Inc. Surgical staple and stapler
US5560532A (en) 1993-10-08 1996-10-01 United States Surgical Corporation Apparatus and method for applying surgical staples to body tissue
US5607436A (en) 1993-10-08 1997-03-04 United States Surgical Corporation Apparatus for applying surgical clips
CA2173990A1 (en) 1993-10-12 1995-04-20 Narasinga Rao A library of glyco-peptides useful for identification of cell adhesion inhibitors
US5776147A (en) 1993-10-20 1998-07-07 Applied Medical Resources Corporation Laparoscopic surgical clamp
US5423857A (en) 1993-11-02 1995-06-13 Ethicon, Inc. Three piece surgical staple
US5527322A (en) 1993-11-08 1996-06-18 Perclose, Inc. Device and method for suturing of internal puncture sites
US5503635A (en) 1993-11-12 1996-04-02 United States Surgical Corporation Apparatus and method for performing compressional anastomoses
US5464413A (en) 1993-11-15 1995-11-07 Siska, Jr.; William Nose clip
US5476505A (en) 1993-11-18 1995-12-19 Advanced Cardiovascular Systems, Inc. Coiled stent and delivery system
NL194533C (en) 1993-12-08 2002-07-02 Benedict Marie Doorschodt Biopsy needle assembly.
US5609597A (en) 1993-12-09 1997-03-11 Lehrer; Theodor Apparatus and method of extracorporeally applying and locking laparoscopic suture and loop ligatures
WO1995016407A1 (en) 1993-12-13 1995-06-22 Brigham And Women's Hospital Aortic valve supporting device
CA2139979A1 (en) 1994-01-13 1995-07-14 Daniel C. Rosenman Spiral surgical tack
FR2715290B1 (en) 1994-01-25 1996-04-05 Newpact Eurl surgical clip ligaments.
US5443477A (en) 1994-02-10 1995-08-22 Stentco, Inc. Apparatus and method for deployment of radially expandable stents by a mechanical linkage
DE4408108A1 (en) 1994-03-10 1995-09-14 Bavaria Med Tech A catheter for injecting a fluid or a Arneimittelns
US6117157A (en) 1994-03-18 2000-09-12 Cook Incorporated Helical embolization coil
WO1995026683A1 (en) 1994-03-31 1995-10-12 Boston Scientific Corporation Vascular plug with vessel locator
US5715987A (en) 1994-04-05 1998-02-10 Tracor Incorporated Constant width, adjustable grip, staple apparatus and method
US5695524A (en) 1994-04-05 1997-12-09 Tracor Aerospace, Inc. Constant width, adjustable grip, staple apparatus and method
US5416584A (en) 1994-04-25 1995-05-16 Honeywell Inc. Sinusoidal noise injection into the dither of a ring laser gyroscope
US5545178A (en) 1994-04-29 1996-08-13 Kensey Nash Corporation System for closing a percutaneous puncture formed by a trocar to prevent tissue at the puncture from herniating
DE4415521C2 (en) 1994-05-04 2003-01-30 Storz Reling Sybill Gesamthand Instrument for use in endoscopic procedures
US5425740A (en) 1994-05-17 1995-06-20 Hutchinson, Jr.; William B. Endoscopic hernia repair clip and method
US5478309A (en) 1994-05-27 1995-12-26 William P. Sweezer, Jr. Catheter system and method for providing cardiopulmonary bypass pump support during heart surgery
US5454413A (en) 1994-06-14 1995-10-03 Morelli; Richard L. Automobile traction enhancement device
US5732872A (en) 1994-06-17 1998-03-31 Heartport, Inc. Surgical stapling instrument
US6302898B1 (en) 1994-06-24 2001-10-16 Advanced Closure Systems, Inc. Devices for sealing punctures in body vessels
US5725552A (en) 1994-07-08 1998-03-10 Aga Medical Corporation Percutaneous catheter directed intravascular occlusion devices
US5544802A (en) 1994-07-27 1996-08-13 Crainich; Lawrence Surgical staple and stapler device therefor
FR2722975A1 (en) 1994-07-28 1996-02-02 Dynamique Sante Sarl Surgical implant for fastening ligament against bone surface
US5582616A (en) 1994-08-05 1996-12-10 Origin Medsystems, Inc. Surgical helical fastener with applicator
US5972023A (en) 1994-08-15 1999-10-26 Eva Corporation Implantation device for an aortic graft method of treating aortic aneurysm
US5549633A (en) 1994-08-24 1996-08-27 Kensey Nash Corporation Apparatus and methods of use for preventing blood seepage at a percutaneous puncture site
US5496332A (en) 1994-10-20 1996-03-05 Cordis Corporation Wound closure apparatus and method for its use
EP0712614B1 (en) 1994-11-15 2003-04-02 Advanced Cardiovascular Systems, Inc. Intraluminal stent for attaching a graft
CA2163824C (en) 1994-11-28 2000-06-20 Advanced Cardiovascular Systems, Inc. Method and apparatus for direct laser cutting of metal stents
WO1996018352A1 (en) 1994-12-14 1996-06-20 Influence, Inc. Staple and thread assembly particularly for use in power-driven staplers for medical suturing
US5620452A (en) 1994-12-22 1997-04-15 Yoon; Inbae Surgical clip with ductile tissue penetrating members
US6896687B2 (en) 1997-05-19 2005-05-24 Pepi Dakov Connectors for hollow anatomical structures and methods of use
JP3798838B2 (en) 1995-01-20 2006-07-19 オリンパス株式会社 Ligating apparatus
US5634936A (en) 1995-02-06 1997-06-03 Scimed Life Systems, Inc. Device for closing a septal defect
WO1996024291A1 (en) 1995-02-07 1996-08-15 Cardiovascular Ventures, Inc. Puncture sealing system
US5649959A (en) 1995-02-10 1997-07-22 Sherwood Medical Company Assembly for sealing a puncture in a vessel
US5695504A (en) 1995-02-24 1997-12-09 Heartport, Inc. Devices and methods for performing a vascular anastomosis
US5695505A (en) 1995-03-09 1997-12-09 Yoon; Inbae Multifunctional spring clips and cartridges and applicators therefor
RU2086192C1 (en) 1995-03-17 1997-08-10 Ялмар Яковлевич Татти Surgical suture appliance
US5575771A (en) 1995-04-24 1996-11-19 Walinsky; Paul Balloon catheter with external guidewire
US5681280A (en) 1995-05-02 1997-10-28 Heart Rhythm Technologies, Inc. Catheter control system
FR2734147B1 (en) 1995-05-19 1997-10-10 Klein Jean Michel An implantable osteosynthesis
US5755727A (en) 1995-06-02 1998-05-26 Cardiologics L.L.C. Method device for locating and sealing a blood vessel
WO1996039946A1 (en) 1995-06-07 1996-12-19 Raychem Corporation Wound closure device
US5645565A (en) 1995-06-13 1997-07-08 Ethicon Endo-Surgery, Inc. Surgical plug
US5700273A (en) 1995-07-14 1997-12-23 C.R. Bard, Inc. Wound closure apparatus and method
US5810846A (en) 1995-08-03 1998-09-22 United States Surgical Corporation Vascular hole closure
WO1997007741A1 (en) 1995-08-24 1997-03-06 Inbae Yoon Suture tie device system and method for suturing anatomical tissue proximate an opening
US6117144A (en) 1995-08-24 2000-09-12 Sutura, Inc. Suturing device and method for sealing an opening in a blood vessel or other biological structure
US5683405A (en) 1995-08-25 1997-11-04 Research Medical Inc. Vascular occluder
US5645566A (en) 1995-09-15 1997-07-08 Sub Q Inc. Apparatus and method for percutaneous sealing of blood vessel punctures
US6071300A (en) 1995-09-15 2000-06-06 Sub-Q Inc. Apparatus and method for percutaneous sealing of blood vessel punctures
WO1998016161A1 (en) 1996-10-11 1998-04-23 Transvascular, Inc. Methods and apparatus for bypassing arterial obstructions and/or performing other transvascular procedures
US5674231A (en) 1995-10-20 1997-10-07 United States Surgical Corporation Apparatus and method for vascular hole closure
US5700270A (en) 1995-10-20 1997-12-23 United States Surgical Corporation Surgical clip applier
WO1997016122A1 (en) 1995-10-31 1997-05-09 Oticon A/S Method and anastomotic instrument for use when performing an end-to-side anastomosis
US5827298A (en) 1995-11-17 1998-10-27 Innovasive Devices, Inc. Surgical fastening system and method for using the same
EP0874591B1 (en) 1995-12-07 2011-04-06 Loma Linda University Medical Center Vascular wound closure device
US6287322B1 (en) 1995-12-07 2001-09-11 Loma Linda University Medical Center Tissue opening locator and everter and method
US6425901B1 (en) 1995-12-07 2002-07-30 Loma Linda University Medical Center Vascular wound closure system
US5626614A (en) 1995-12-22 1997-05-06 Applied Medical Resources Corporation T-anchor suturing device and method for using same
DE69716779D1 (en) 1996-01-30 2002-12-05 Medtronic Inc Products and methods for production of dilators
CN1216930A (en) 1996-02-02 1999-05-19 血管转换公司 Device, system and method for interstitial transvascular intervention
DE19604817C2 (en) 1996-02-09 2003-06-12 Pfm Prod Fuer Die Med Ag Device for closure of defect openings in the human or animal body
US5810776A (en) 1996-02-13 1998-09-22 Imagyn Medical, Inc. Method and apparatus for performing laparoscopy
US5769870A (en) 1996-02-20 1998-06-23 Cardiothoracic Systems, Inc. Perfusion device for maintaining blood flow in a vessel while isolating an anastomosis
US5951575A (en) 1996-03-01 1999-09-14 Heartport, Inc. Apparatus and methods for rotationally deploying needles
US5810851A (en) 1996-03-05 1998-09-22 Yoon; Inbae Suture spring device
US5782844A (en) 1996-03-05 1998-07-21 Inbae Yoon Suture spring device applicator
US5728132A (en) 1996-04-08 1998-03-17 Tricardia, L.L.C. Self-sealing vascular access device
US6149660A (en) 1996-04-22 2000-11-21 Vnus Medical Technologies, Inc. Method and apparatus for delivery of an appliance in a vessel
US6117125A (en) 1996-05-02 2000-09-12 Cook Incorporated Method for predetermining uniform flow rate of a fluid from a tubular body and device therefrom
EP0900051A1 (en) 1996-05-08 1999-03-10 Salviac Limited An occluder device
DE69724424D1 (en) * 1996-05-13 2003-10-02 Novartis Consumer Health Sa Oral delivery system
US5690674A (en) 1996-07-02 1997-11-25 Cordis Corporation Wound closure with plug
US5728133A (en) 1996-07-09 1998-03-17 Cardiologics, L.L.C. Anchoring device and method for sealing percutaneous punctures in vessels
US5957900A (en) 1996-07-10 1999-09-28 Asahi Kogaku Kogyo Kabushiki Kaisha Treatment accessory for endoscope
US5797933A (en) 1996-07-16 1998-08-25 Heartport, Inc. Coronary shunt and method of use
US5833698A (en) 1996-07-23 1998-11-10 United States Surgical Corporation Anastomosis instrument and method
US5820631A (en) 1996-08-01 1998-10-13 Nr Medical, Inc. Device and method for suturing tissue adjacent to a blood vessel
US5830217A (en) * 1996-08-09 1998-11-03 Thomas J. Fogarty Soluble fixation device and method for stent delivery catheters
US5902310A (en) 1996-08-12 1999-05-11 Ethicon Endo-Surgery, Inc. Apparatus and method for marking tissue
US6482224B1 (en) 1996-08-22 2002-11-19 The Trustees Of Columbia University In The City Of New York Endovascular flexible stapling device
ES2208974T3 (en) 1996-08-23 2004-06-16 Cook Biotech, Inc. Prosthetic grafts, materials and methods.
US6488692B1 (en) 1996-09-16 2002-12-03 Origin Medsystems, Inc. Access and cannulation device and method for rapidly placing same and for rapidly closing same in minimally invasive surgery
US5830221A (en) 1996-09-20 1998-11-03 United States Surgical Corporation Coil fastener applier
US6152936A (en) 1996-09-23 2000-11-28 Esd Medical, Llc Surgical loop delivery device
US5948001A (en) 1996-10-03 1999-09-07 United States Surgical Corporation System for suture anchor placement
US5755778A (en) 1996-10-16 1998-05-26 Nitinol Medical Technologies, Inc. Anastomosis device
WO1998018389A1 (en) 1996-10-25 1998-05-07 University Of Massachusetts Surgical vessel clips and methods for closing vessels
US5749826A (en) 1996-11-06 1998-05-12 Faulkner; James W. Urinary incontinence control device
DE69737208T2 (en) 1996-11-15 2007-11-08 Cook Inc., Bloomington The stent delivery device having a separable case
US5947999A (en) 1996-12-03 1999-09-07 Groiso; Jorge A. Surgical clip and method
US6004341A (en) 1996-12-05 1999-12-21 Loma Linda University Medical Center Vascular wound closure device
US5735873A (en) 1996-12-19 1998-04-07 Maclean; David S. Surgical tool handle
US5879366A (en) 1996-12-20 1999-03-09 W.L. Gore & Associates, Inc. Self-expanding defect closure device and method of making and using
US5782861A (en) 1996-12-23 1998-07-21 Sub Q Inc. Percutaneous hemostasis device
US5957938A (en) 1997-02-05 1999-09-28 United States Surgical Corporation Tissue everting needle
US6146385A (en) 1997-02-11 2000-11-14 Smith & Nephew, Inc. Repairing cartilage
US6056769A (en) 1997-02-11 2000-05-02 Biointerventional Corporation Expansile device for use in blood vessels and tracts in the body and tension application device for use therewith and method
US5782860A (en) 1997-02-11 1998-07-21 Biointerventional Corporation Closure device for percutaneous occlusion of puncture sites and tracts in the human body and method
US6045570A (en) 1997-02-11 2000-04-04 Biointerventional Corporation Biological sealant mixture and system for use in percutaneous occlusion of puncture sites and tracts in the human body and method
US6056770A (en) 1997-02-11 2000-05-02 Biointerventional Corporation Expansile device for use in blood vessels and tracts in the body and method
US5951589A (en) 1997-02-11 1999-09-14 Biointerventional Corporation Expansile device for use in blood vessels and tracts in the body and tension application device for use therewith and method
EP0858776A3 (en) 1997-02-14 2000-01-12 Tricardia, L.L.C. Hemostatic agent delivery device having built-in pressure sensor
WO1998039053A1 (en) 1997-03-06 1998-09-11 Scimed Life Systems, Inc. Distal protection device and method
US5752966A (en) 1997-03-07 1998-05-19 Chang; David W. Exovascular anastomotic device
US5908149A (en) 1997-03-12 1999-06-01 Ethicon Endo-Surgery, Inc. Skin stapler with multi-directional release mechanism
DE29723736U1 (en) 1997-03-18 1999-02-18 Wurster Helmut Dipl Ing Surgical staplers for connecting tissue parts
DE19711288B4 (en) 1997-03-18 2004-11-04 Helmut Dipl.-Ing. Wurster Applicator for receiving and closing a surgical clip
US5984948A (en) 1997-04-14 1999-11-16 Hasson; Harrith M. Device for closing an opening in tissue and method of closing a tissue opening using the device
US5897487A (en) 1997-04-15 1999-04-27 Asahi Kogaku Kogyo Kabushiki Kaisha Front end hood for endoscope
EP1011532B1 (en) 1997-04-23 2014-05-07 Ethicon Endo-Surgery, Inc. Bifurcated stent and distal protection system
US5957936A (en) 1997-05-01 1999-09-28 Inbae Yoon Instrument assemblies for performing anatomical tissue ligation
US6409739B1 (en) 1997-05-19 2002-06-25 Cardio Medical Solutions, Inc. Device and method for assisting end-to side anastomosis
US6706051B2 (en) 1998-04-08 2004-03-16 Bhk Holding, Ltd. Hemostatic system for body cavities
US6443158B1 (en) 1997-06-19 2002-09-03 Scimed Life Systems, Inc. Percutaneous coronary artery bypass through a venous vessel
US6001110A (en) 1997-06-20 1999-12-14 Boston Scientific Corporation Hemostatic clips
US5957940A (en) 1997-06-30 1999-09-28 Eva Corporation Fasteners for use in the surgical repair of aneurysms
US5928260A (en) 1997-07-10 1999-07-27 Scimed Life Systems, Inc. Removable occlusion system for aneurysm neck
EP0895753A1 (en) 1997-07-31 1999-02-10 Academisch Ziekenhuis Utrecht Temporary vascular seal for anastomosis
US6063114A (en) 1997-09-04 2000-05-16 Kensey Nash Corporation Connector system for vessels, ducts, lumens or hollow organs and methods of use
US5954732A (en) 1997-09-10 1999-09-21 Hart; Charles C. Suturing apparatus and method
US6059800A (en) 1997-09-10 2000-05-09 Applied Medical Resources Corporation Suturing apparatus and method
FR2768324B1 (en) 1997-09-12 1999-12-10 Jacques Seguin A surgical instrument for percutaneously, fixing one to the other two zones of soft tissue, usually spaced apart
US5964782A (en) 1997-09-18 1999-10-12 Scimed Life Systems, Inc. Closure device and method
US5928251A (en) 1997-09-18 1999-07-27 United States Surgical Corporation Occlusion clamp and occlusion clamp applicator
US5868762A (en) 1997-09-25 1999-02-09 Sub-Q, Inc. Percutaneous hemostatic suturing device and method
US5984949A (en) 1997-10-06 1999-11-16 Levin; John M. Tissue hooks and tools for applying same
US5984934A (en) 1997-10-10 1999-11-16 Applied Medical Resources Corporation Low-profile surgical clip
US6117148A (en) 1997-10-17 2000-09-12 Ravo; Biagio Intraluminal anastomotic device
NL1007349C2 (en) 1997-10-24 1999-04-27 Suyker Wilhelmus Joseph Leonardus System for mechanical production of anastomoses between hollow structures; as well as device and applicator for use therewith.
US5951518A (en) 1997-10-31 1999-09-14 Teleflex, Incorporated Introducing device with flared sheath end
US5906631A (en) 1997-12-05 1999-05-25 Surface Genesis, Inc. Method and device for sealing vascular puncture wounds
US6254642B1 (en) 1997-12-09 2001-07-03 Thomas V. Taylor Perorally insertable gastroesophageal anti-reflux valve prosthesis and tool for implantation thereof
US5976174A (en) 1997-12-15 1999-11-02 Ruiz; Carlos E. Medical hole closure device and methods of use
US6036720A (en) 1997-12-15 2000-03-14 Target Therapeutics, Inc. Sheet metal aneurysm neck bridge
US6626919B1 (en) 1997-12-29 2003-09-30 Lee L. Swanstrom Method and apparatus for attaching or locking an implant to an anatomic vessel or hollow organ wall
US5976161A (en) 1998-01-07 1999-11-02 University Of New Mexico Tissue everting apparatus and method
US6033427A (en) 1998-01-07 2000-03-07 Lee; Benjamin I. Method and device for percutaneous sealing of internal puncture sites
DE69833882D1 (en) 1998-01-30 2006-05-11 St Jude Medical Atg Inc Medical graft connector or plug as well as process for their production
US6036703A (en) 1998-02-06 2000-03-14 Ethicon Endo-Surgery Inc. Method and apparatus for establishing anastomotic passageways
EP1054628A1 (en) 1998-02-10 2000-11-29 Jump, Jeffrey Surgical device for occlusion of defects
US6280460B1 (en) 1998-02-13 2001-08-28 Heartport, Inc. Devices and methods for performing vascular anastomosis
US5951576A (en) 1998-03-02 1999-09-14 Wakabayashi; Akio End-to-side vascular anastomosing stapling device
WO1999048427A1 (en) 1998-03-20 1999-09-30 Sumit Roy Method and device for suturless anastomosis
JP4448614B2 (en) 1998-03-31 2010-04-14 メドトロニック バスキュラー インコーポレイテッドMedtronic Vascular,Inc. Tissue penetrating catheter system with a built-in image transducers
US6241740B1 (en) 1998-04-09 2001-06-05 Origin Medsystems, Inc. System and method of use for ligating and cutting tissue
JP2003510104A (en) 1998-05-11 2003-03-18 サージカル・コネクションズ・インコーポレイテッド Apparatus and methods for treating stress urinary incontinence e.g.
US7083588B1 (en) 1998-05-26 2006-08-01 Medtronic Vascular, Inc. Apparatus for providing coronary retroperfusion and methods of use
US6726704B1 (en) 1998-05-29 2004-04-27 By-Pass, Inc. Advanced closure device
US7063711B1 (en) 1998-05-29 2006-06-20 By-Pass, Inc. Vascular surgery
WO2000056226A1 (en) 1999-03-19 2000-09-28 By-Pass, Inc. Vascular surgery
WO1999062415A1 (en) 1998-05-29 1999-12-09 By-Pass, Inc. Methods and devices for vascular surgery
WO2000056227A1 (en) 1999-03-19 2000-09-28 By-Pass, Inc. Advanced closure device
US7060084B1 (en) 1998-05-29 2006-06-13 By-Pass, Inc. Vascular closure device
US7396359B1 (en) 1998-05-29 2008-07-08 Bypass, Inc. Vascular port device
US20050283188A1 (en) 1998-05-29 2005-12-22 By-Pass, Inc. Vascular closure device
US5919207A (en) 1998-06-02 1999-07-06 Taheri; Syde A. Percutaneous arterial closure with staples
US6599311B1 (en) 1998-06-05 2003-07-29 Broncus Technologies, Inc. Method and assembly for lung volume reduction
US5910155A (en) 1998-06-05 1999-06-08 United States Surgical Corporation Vascular wound closure system
US5941890A (en) 1998-06-26 1999-08-24 Ethicon Endo-Surgery, Inc. Implantable surgical marker
US6228098B1 (en) 1998-07-10 2001-05-08 General Surgical Innovations, Inc. Apparatus and method for surgical fastening
US6048358A (en) 1998-07-13 2000-04-11 Barak; Shlomo Method and apparatus for hemostasis following arterial catheterization
WO2000007505A1 (en) 1998-08-04 2000-02-17 Fusion Medical Technologies, Inc. Percutaneous tissue track closure assembly and method
DE19859950C2 (en) 1998-08-11 2003-08-21 S & T Ag Neuhausen Am Rheinfal A surgical stapler and apparatus for their application
US6206913B1 (en) 1998-08-12 2001-03-27 Vascular Innovations, Inc. Method and system for attaching a graft to a blood vessel
US6605294B2 (en) 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels
US6198974B1 (en) 1998-08-14 2001-03-06 Cordis Webster, Inc. Bi-directional steerable catheter
US6179860B1 (en) 1998-08-19 2001-01-30 Artemis Medical, Inc. Target tissue localization device and method
DE19839188C2 (en) 1998-08-28 2003-08-21 Storz Endoskop Gmbh Schaffhaus endoscope
US6200329B1 (en) 1998-08-31 2001-03-13 Smith & Nephew, Inc. Suture collet
WO2000016701A1 (en) 1998-09-18 2000-03-30 United States Surgical Corporation Endovascular fastener applicator
US6296657B1 (en) 1998-10-07 2001-10-02 Gregory G. Brucker Vascular sealing device and method
US6019779A (en) 1998-10-09 2000-02-01 Intratherapeutics Inc. Multi-filar coil medical stent
US6220248B1 (en) 1998-10-21 2001-04-24 Ethicon Endo-Surgery, Inc. Method for implanting a biopsy marker
JP4164235B2 (en) 1998-10-23 2008-10-15 コビディエン アクチェンゲゼルシャフト Endoscopic bipolar electrosurgical forceps
US6152937A (en) 1998-11-06 2000-11-28 St. Jude Medical Cardiovascular Group, Inc. Medical graft connector and methods of making and installing same
US6113612A (en) 1998-11-06 2000-09-05 St. Jude Medical Cardiovascular Group, Inc. Medical anastomosis apparatus
US6152144A (en) 1998-11-06 2000-11-28 Appriva Medical, Inc. Method and device for left atrial appendage occlusion
US6102271A (en) 1998-11-23 2000-08-15 Ethicon Endo-Surgery, Inc. Circular stapler for hemorrhoidal surgery
US6200330B1 (en) 1998-11-23 2001-03-13 Theodore V. Benderev Systems for securing sutures, grafts and soft tissue to bone and periosteum
US6080183A (en) 1998-11-24 2000-06-27 Embol-X, Inc. Sutureless vessel plug and methods of use
US6210407B1 (en) 1998-12-03 2001-04-03 Cordis Webster, Inc. Bi-directional electrode catheter
US6126675A (en) 1999-01-11 2000-10-03 Ethicon, Inc. Bioabsorbable device and method for sealing vascular punctures
US6074395A (en) 1999-02-02 2000-06-13 Linvatec Corporation Cannulated tissue anchor insertion system
US6120524A (en) 1999-02-16 2000-09-19 Taheri; Syde A. Device for closing an arterial puncture and method
US6613059B2 (en) 1999-03-01 2003-09-02 Coalescent Surgical, Inc. Tissue connector apparatus and methods
US6136010A (en) 1999-03-04 2000-10-24 Perclose, Inc. Articulating suturing device and method
US7235087B2 (en) 1999-03-04 2007-06-26 Abbott Park Articulating suturing device and method
US20040092964A1 (en) 1999-03-04 2004-05-13 Modesitt D. Bruce Articulating suturing device and method
US6964668B2 (en) 1999-03-04 2005-11-15 Abbott Laboratories Articulating suturing device and method
WO2000053104A8 (en) 1999-03-09 2001-01-25 St Jude Medical Cardiovascular Medical grafting methods and apparatus
WO2000055932A1 (en) 1999-03-15 2000-09-21 Bolder Technologies Corporation Tin-clad substrates for use as current collectors, batteries comprised thereof and methods for preparing same
WO2000056228A1 (en) 1999-03-19 2000-09-28 By-Pass, Inc. Low profile anastomosis connector
US20040087985A1 (en) 1999-03-19 2004-05-06 Amir Loshakove Graft and connector delivery
US20040044350A1 (en) 1999-04-09 2004-03-04 Evalve, Inc. Steerable access sheath and methods of use
US6752813B2 (en) 1999-04-09 2004-06-22 Evalve, Inc. Methods and devices for capturing and fixing leaflets in valve repair
US7563267B2 (en) 1999-04-09 2009-07-21 Evalve, Inc. Fixation device and methods for engaging tissue
US6632197B2 (en) 1999-04-16 2003-10-14 Thomas R. Lyon Clear view cannula
US6623494B1 (en) 1999-04-16 2003-09-23 Integrated Vascular Interventional Technologies, L.C. (Ivit, Lc) Methods and systems for intraluminally directed vascular anastomosis
US6626921B2 (en) 1999-04-16 2003-09-30 Integrated Vascular Interventional Technologies, L.C. Externally positioned anvil apparatus for cutting anastomosis
US6375671B1 (en) 1999-04-19 2002-04-23 Nipro Corporation Closure device for transcatheter operations
DE60014878D1 (en) 1999-04-21 2004-11-18 Romolo Igino Gazzani Semi-rigid compression clamp for use in sternotomy and pliers for application
US6287335B1 (en) 1999-04-26 2001-09-11 William J. Drasler Intravascular folded tubular endoprosthesis
US6302870B1 (en) 1999-04-29 2001-10-16 Precision Vascular Systems, Inc. Apparatus for injecting fluids into the walls of blood vessels, body cavities, and the like
US6261258B1 (en) 1999-05-03 2001-07-17 Marius Saines Hemostatic device for angioplasty
US6712836B1 (en) 1999-05-13 2004-03-30 St. Jude Medical Atg, Inc. Apparatus and methods for closing septal defects and occluding blood flow
WO2000069364A3 (en) 1999-05-18 2001-02-01 Vascular Innovations Inc Implantable medical device such as an anastomosis device
US6699256B1 (en) 1999-06-04 2004-03-02 St. Jude Medical Atg, Inc. Medical grafting apparatus and methods
US6165204A (en) 1999-06-11 2000-12-26 Scion International, Inc. Shaped suture clip, appliance and method therefor
US6860895B1 (en) 1999-06-18 2005-03-01 Radi Medical Systems Ab Tool, a sealing device, a system and a method for closing a wound
US6626899B2 (en) 1999-06-25 2003-09-30 Nidus Medical, Llc Apparatus and methods for treating tissue
US6398796B2 (en) 1999-07-13 2002-06-04 Scion Cardio-Vascular, Inc. Suture with toggle and delivery system
US6206895B1 (en) 1999-07-13 2001-03-27 Scion Cardio-Vascular, Inc. Suture with toggle and delivery system
US6267773B1 (en) 1999-07-15 2001-07-31 Donald L. Gadberry Low profile surgical clip
JP3917332B2 (en) 1999-08-04 2007-05-23 ペンタックス株式会社 Operating wire connecting portion of the endoscope treatment tool
US6110184A (en) 1999-08-04 2000-08-29 Weadock; Kevin S. Introducer with vascular sealing mechanism
EP1210014A1 (en) 1999-09-07 2002-06-05 Microvena Corporation Retrievable septal defect closure device
ES2283316T3 (en) 1999-09-13 2007-11-01 Rex Medical, Lp vascular closure.
US7341595B2 (en) 1999-09-13 2008-03-11 Rex Medical, L.P Vascular hole closure device
US7267679B2 (en) 1999-09-13 2007-09-11 Rex Medical, L.P Vascular hole closure device
US6358258B1 (en) 1999-09-14 2002-03-19 Abbott Laboratories Device and method for performing end-to-side anastomosis
US6421899B1 (en) 1999-09-15 2002-07-23 Emhart Llc Extraction and adjustment tool for tangless inserts
US6231561B1 (en) 1999-09-20 2001-05-15 Appriva Medical, Inc. Method and apparatus for closing a body lumen
US6984219B2 (en) 1999-09-23 2006-01-10 Mark Ashby Depth and puncture control for blood vessel hemostasis system
JP4759194B2 (en) 1999-09-23 2011-08-31 サブ−キュー・インコーポレーテッド Device for determining the depth of the incision
US6319258B1 (en) 1999-09-29 2001-11-20 Ethicon, Inc. Absorbable rivet/pin applier for use in surgical procedures
US6626930B1 (en) 1999-10-21 2003-09-30 Edwards Lifesciences Corporation Minimally invasive mitral valve repair method and apparatus
US6409753B1 (en) 1999-10-26 2002-06-25 Scimed Life Systems, Inc. Flexible stent
US6689150B1 (en) 1999-10-27 2004-02-10 Atritech, Inc. Filter apparatus for ostium of left atrial appendage
WO2001034035A1 (en) 1999-11-05 2001-05-17 Onux Medical, Inc. Apparatus and method for approximating and closing the walls of a hole or puncture in a physiological shell structure
US6273903B1 (en) 1999-11-08 2001-08-14 Peter J. Wilk Endoscopic stapling device and related staple
US6689062B1 (en) 1999-11-23 2004-02-10 Microaccess Medical Systems, Inc. Method and apparatus for transesophageal cardiovascular procedures
US6695854B1 (en) 1999-11-29 2004-02-24 General Surgical Innovations, Inc. Blood vessel clip and applicator
US6602263B1 (en) 1999-11-30 2003-08-05 St. Jude Medical Atg, Inc. Medical grafting methods and apparatus
US6569173B1 (en) 1999-12-14 2003-05-27 Integrated Vascular Interventional Technologies, L.C. Compression plate anastomosis apparatus
US20050187564A1 (en) 1999-12-23 2005-08-25 Swaminathan Jayaraman Occlusive coil manufacturing and delivery
US6790218B2 (en) 1999-12-23 2004-09-14 Swaminathan Jayaraman Occlusive coil manufacture and delivery
GB9930654D0 (en) 1999-12-23 2000-02-16 Halpin Richard M B Device for controlling extra-vascular haemorrhage
EP1110510B1 (en) 1999-12-23 2002-03-27 Karl Storz GmbH & Co. KG Screw driven non-centrally
JP4399141B2 (en) 2000-01-05 2010-01-13 インテグレイテッド・バスキュラー・システムズ・インコーポレイテッドIntegrated Vascular Systems, Inc. Apparatus for closing the tissue puncture
US6780197B2 (en) 2000-01-05 2004-08-24 Integrated Vascular Systems, Inc. Apparatus and methods for delivering a vascular closure device to a body lumen
US6197042B1 (en) 2000-01-05 2001-03-06 Medical Technology Group, Inc. Vascular sheath with puncture site closure apparatus and methods of use
US6461364B1 (en) 2000-01-05 2002-10-08 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US6942674B2 (en) 2000-01-05 2005-09-13 Integrated Vascular Systems, Inc. Apparatus and methods for delivering a closure device
US7842068B2 (en) 2000-12-07 2010-11-30 Integrated Vascular Systems, Inc. Apparatus and methods for providing tactile feedback while delivering a closure device
US8758400B2 (en) 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Closure system and methods of use
US6391048B1 (en) 2000-01-05 2002-05-21 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US9579091B2 (en) 2000-01-05 2017-02-28 Integrated Vascular Systems, Inc. Closure system and methods of use
JP4347486B2 (en) 2000-01-24 2009-10-21 株式会社ハイレックスコーポレーション Indwelling catheter
US6547806B1 (en) 2000-02-04 2003-04-15 Ni Ding Vascular sealing device and method of use
GB0002970D0 (en) 2000-02-09 2000-03-29 Anson Medical Ltd Fixator for the repair of articles
US6786915B2 (en) 2000-04-19 2004-09-07 Radi Medical Systems Ab Reinforced absorbable medical sealing device
JP3844661B2 (en) 2000-04-19 2006-11-15 ラディ・メディカル・システムズ・アクチェボラーグ Intra-arterial emboli
US6942691B1 (en) 2000-04-27 2005-09-13 Timothy A. M. Chuter Modular bifurcated graft for endovascular aneurysm repair
US7361185B2 (en) 2001-05-09 2008-04-22 Canica Design, Inc. Clinical and surgical system and method for moving and stretching plastic tissue
US6305891B1 (en) 2000-05-15 2001-10-23 Mark S. Burlingame Fastening device and a spacer, and a method of using the same
WO2001091628A3 (en) 2000-05-31 2003-10-30 Origin Medsystems Inc Method and apparatus for performing end-to-end and end-to-side anastomosis with eversion of tissue edges
US6402765B1 (en) 2000-06-12 2002-06-11 Niti Alloys Technologies Ltd. Surgical clip
DE60132005D1 (en) 2000-06-23 2008-01-31 Viacor Inc Automatic circular convolution for Mitral Valve Repair
US6443963B1 (en) 2000-07-26 2002-09-03 Orthopaedic Biosystems, Ltd. Apparatus and method for repairing or reattaching soft tissue
DE60112945D1 (en) 2000-07-27 2005-09-29 Synthes Ag Schädelkalottenfixiereinrichtung
US6428472B1 (en) 2000-08-08 2002-08-06 Kent Haas Surgical retractor having a malleable support
CA2419196A1 (en) 2000-08-11 2002-02-21 Sdgi Holdings, Inc. Surgical instrumentation and method for treatment of the spine
US6572629B2 (en) 2000-08-17 2003-06-03 Johns Hopkins University Gastric reduction endoscopy
US6767356B2 (en) 2000-09-01 2004-07-27 Angiolink Corporation Advanced wound site management systems and methods
US6755842B2 (en) 2000-09-01 2004-06-29 Angiolink Corporation Advanced wound site management systems and methods
US20040093024A1 (en) 2000-09-01 2004-05-13 James Lousararian Advanced wound site management systems and methods
US7074232B2 (en) 2000-09-01 2006-07-11 Medtronic Angiolink, Inc. Advanced wound site management systems and methods
US6533762B2 (en) 2000-09-01 2003-03-18 Angiolink Corporation Advanced wound site management systems and methods
US7338506B2 (en) 2001-09-05 2008-03-04 Caro Nicholas C Scleral clip and procedures for using same
DE60143324D1 (en) 2000-09-08 2010-12-02 Abbott Vascular Inc An apparatus for locating a punctured blood vessel
US6551319B2 (en) 2000-11-08 2003-04-22 The Cleveland Clinic Foundation Apparatus for implantation into bone
US6626918B1 (en) 2000-10-06 2003-09-30 Medical Technology Group Apparatus and methods for positioning a vascular sheath
US6633234B2 (en) 2000-10-20 2003-10-14 Ethicon Endo-Surgery, Inc. Method for detecting blade breakage using rate and/or impedance information
US6663633B1 (en) 2000-10-25 2003-12-16 Pierson, Iii Raymond H. Helical orthopedic fixation and reduction device, insertion system, and associated methods
US6645225B1 (en) 2000-11-01 2003-11-11 Alvan W. Atkinson Method and apparatus for plugging a patent foramen ovale formed in the heart
WO2002076281A3 (en) 2000-11-07 2003-06-19 Artemis Medical Inc Tissue separator assembly and method
US6966917B1 (en) 2000-11-09 2005-11-22 Innovation Interventional Technologies B.V. Deformable connector for mechanically connecting hollow structures
US6884235B2 (en) 2000-12-06 2005-04-26 Rex Medical, L.P. Introducer sheath with retainer and radiopaque insert
US8690910B2 (en) 2000-12-07 2014-04-08 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7211101B2 (en) 2000-12-07 2007-05-01 Abbott Vascular Devices Methods for manufacturing a clip and clip
US6719777B2 (en) 2000-12-07 2004-04-13 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7806904B2 (en) 2000-12-07 2010-10-05 Integrated Vascular Systems, Inc. Closure device
US6969397B2 (en) 2000-12-14 2005-11-29 Ensure Medical, Inc. Guide wire element for positioning vascular closure devices and methods for use
US6890343B2 (en) 2000-12-14 2005-05-10 Ensure Medical, Inc. Plug with detachable guidewire element and methods for use
US8083768B2 (en) 2000-12-14 2011-12-27 Ensure Medical, Inc. Vascular plug having composite construction
US6623509B2 (en) 2000-12-14 2003-09-23 Core Medical, Inc. Apparatus and methods for sealing vascular punctures
CA2485282C (en) 2002-05-10 2011-05-24 Core Medical, Inc. Plug with collet and detachable guidewire element for positioning vascular closure devices and methods for use
US6896692B2 (en) 2000-12-14 2005-05-24 Ensure Medical, Inc. Plug with collet and apparatus and method for delivering such plugs
US6855161B2 (en) 2000-12-27 2005-02-15 Advanced Cardiovascular Systems, Inc. Radiopaque nitinol alloys for medical devices
US20040059376A1 (en) 2001-01-31 2004-03-25 Helmut Breuniger Device for the introduction and fashioning of skin clips
US6703047B2 (en) 2001-02-02 2004-03-09 Incept Llc Dehydrated hydrogel precursor-based, tissue adherent compositions and methods of use
US6569185B2 (en) 2001-02-15 2003-05-27 Scimed Life Systems Inc Continuous infusion technique for arterial sealing
US6743195B2 (en) 2001-03-14 2004-06-01 Cardiodex Balloon method and apparatus for vascular closure following arterial catheterization
USD457958S1 (en) 2001-04-06 2002-05-28 Sherwood Services Ag Vessel sealer and divider
US7025776B1 (en) 2001-04-24 2006-04-11 Advanced Catheter Engineering, Inc. Arteriotomy closure devices and techniques
US6535764B2 (en) 2001-05-01 2003-03-18 Intrapace, Inc. Gastric treatment and diagnosis device and method
US20020173803A1 (en) 2001-05-01 2002-11-21 Stephen Ainsworth Self-closing surgical clip for tissue
JP4267867B2 (en) 2001-05-03 2009-05-27 ラディ・メディカル・システムズ・アクチェボラーグ Guide instrument of the wound closure element
DE60104667T2 (en) 2001-05-09 2005-01-05 Radi Medical Systems Ab An apparatus for sealing an arterial perforation
US7087088B2 (en) 2001-05-24 2006-08-08 Torax Medical, Inc. Methods and apparatus for regulating the flow of matter through body tubing
US7083629B2 (en) 2001-05-30 2006-08-01 Satiety, Inc. Overtube apparatus for insertion into a body
US6537300B2 (en) 2001-05-30 2003-03-25 Scimed Life Systems, Inc. Implantable obstruction device for septal defects
US7338514B2 (en) 2001-06-01 2008-03-04 St. Jude Medical, Cardiology Division, Inc. Closure devices, related delivery methods and tools, and related methods of use
WO2002098302A1 (en) 2001-06-07 2002-12-12 Christy Cummins Surgical staple
EP1392181B1 (en) 2001-06-08 2014-10-15 Morris Innovative Research, Inc. Method and apparatus for sealing access
US7033379B2 (en) 2001-06-08 2006-04-25 Incisive Surgical, Inc. Suture lock having non-through bore capture zone
JP4159805B2 (en) 2001-06-15 2008-10-01 ラディ・メディカル・システムズ・アクチェボラーグ The pushing mechanism for the closure method
US20020198589A1 (en) 2001-06-22 2002-12-26 Leong Veronica Jade Tessellated stent and method of manufacture
US6626920B2 (en) 2001-07-05 2003-09-30 Converge Medical, Inc. Distal anastomosis system
US7288105B2 (en) 2001-08-01 2007-10-30 Ev3 Endovascular, Inc. Tissue opening occluder
US7208005B2 (en) 2001-08-06 2007-04-24 The Penn State Research Foundation Multifunctional tool and method for minimally invasive surgery
CA2456811A1 (en) 2001-08-09 2003-02-20 Christy Cummins Surgical stapling device and method
US6645205B2 (en) 2001-08-15 2003-11-11 Core Medical, Inc. Apparatus and methods for reducing lung volume
US6929634B2 (en) 2001-08-22 2005-08-16 Gore Enterprise Holdings, Inc. Apparatus and methods for treating stroke and controlling cerebral flow characteristics
US6634537B2 (en) 2001-08-23 2003-10-21 Tung-I Chen Detachable insulation wire-pressing element of a stapling device
US6776784B2 (en) 2001-09-06 2004-08-17 Core Medical, Inc. Clip apparatus for closing septal defects and methods of use
US20090054912A1 (en) 2001-09-06 2009-02-26 Heanue Taylor A Systems and Methods for Treating Septal Defects
US6596013B2 (en) 2001-09-20 2003-07-22 Scimed Life Systems, Inc. Method and apparatus for treating septal defects
US6685707B2 (en) 2001-09-25 2004-02-03 Walter Lorenz Surgical, Inc. Cranial clamp and method for fixating a bone plate
JP2003190175A (en) 2001-11-15 2003-07-08 Cordis Neurovascular Inc Aneurysm neck cover for sealing aneurysm
US6620165B2 (en) 2001-11-26 2003-09-16 Bioplate, Inc. Bone alignment and fixation plate and installation method
US20080249504A1 (en) 2007-04-06 2008-10-09 Lattouf Omar M Instrument port
US20030139819A1 (en) 2002-01-18 2003-07-24 Beer Nicholas De Method and apparatus for closing septal defects
US7311702B2 (en) 2002-01-18 2007-12-25 Std Manufacturing, Inc. Ablation technology for catheter based delivery systems
US20040093027A1 (en) 2002-03-04 2004-05-13 Walter Fabisiak Barbed tissue connector for sealing vascular puncture wounds
US7077850B2 (en) 2002-05-01 2006-07-18 Scimed Life Systems, Inc. Tissue fastening devices and related insertion tools and methods
CA2488688A1 (en) 2002-06-04 2003-12-11 Christy Cummins Blood vessel closure clip and delivery device
CA2488337A1 (en) 2002-06-05 2003-12-18 Nmt Medical, Inc. Patent foramen ovale (pfo) closure device with radial and circumferential support
US20040002763A1 (en) 2002-06-27 2004-01-01 Raymedica, Inc. Spinal disc anulus occlusion device and method of use
EP1646320B1 (en) 2002-07-03 2009-02-25 Abbott Vascular Inc Surgical stapling device
EP1526810B1 (en) 2002-07-31 2009-04-15 Abbott Laboratories Vascular Enterprises Limited Apparatus for sealing surgical punctures
WO2004012602A3 (en) 2002-08-01 2004-03-18 Abbott Lab Vascular Entpr Ltd Autologous wound sealing apparatus
EP1528901A1 (en) 2002-08-15 2005-05-11 GMP Cardiac Care, Inc. Stent-graft with rails
WO2004026147A3 (en) 2002-09-23 2004-08-12 Nmt Medical Inc Septal puncture device
US20040068273A1 (en) 2002-10-02 2004-04-08 Ibionics Corporation Automatic laparoscopic incision closing apparatus
US7087064B1 (en) 2002-10-15 2006-08-08 Advanced Cardiovascular Systems, Inc. Apparatuses and methods for heart valve repair
US7493154B2 (en) 2002-10-23 2009-02-17 Medtronic, Inc. Methods and apparatus for locating body vessels and occlusions in body vessels
US7416554B2 (en) 2002-12-11 2008-08-26 Usgi Medical Inc Apparatus and methods for forming and securing gastrointestinal tissue folds
US7160309B2 (en) 2002-12-31 2007-01-09 Laveille Kao Voss Systems for anchoring a medical device in a body lumen
GB0300786D0 (en) 2003-01-14 2003-02-12 Barker Stephen G E Laparoscopic port hernia device
US7008442B2 (en) 2003-01-20 2006-03-07 Medtronic Vascular, Inc. Vascular sealant delivery device and sheath introducer and method
US7115135B2 (en) 2003-01-22 2006-10-03 Cardia, Inc. Occlusion device having five or more arms
US8398656B2 (en) 2003-01-30 2013-03-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US7857828B2 (en) 2003-01-30 2010-12-28 Integrated Vascular Systems, Inc. Clip applier and methods of use
US7905900B2 (en) 2003-01-30 2011-03-15 Integrated Vascular Systems, Inc. Clip applier and methods of use
JP4094445B2 (en) 2003-01-31 2008-06-04 オリンパス株式会社 Endoscopic mucosal resection tool
DE60309281D1 (en) 2003-02-10 2006-12-07 Heraeus Gmbh W C Improved metal alloy for medical devices and implants
US20070276488A1 (en) 2003-02-10 2007-11-29 Jurgen Wachter Medical implant or device
US7534242B2 (en) 2003-02-25 2009-05-19 Artemis Medical, Inc. Tissue separating catheter assembly and method
WO2004080275A3 (en) 2003-03-06 2005-05-19 Applied Med Resources Spring clip and method for assembling same
DE10310995B3 (en) 2003-03-06 2004-09-16 Aesculap Ag & Co. Kg Device for closing a branch canal and applicator
US7850654B2 (en) 2003-04-24 2010-12-14 St. Jude Medical Puerto Rico B.V. Device and method for positioning a closure device
US7112216B2 (en) 2003-05-28 2006-09-26 Boston Scientific Scimed, Inc. Stent with tapered flexibility
US6942641B2 (en) 2003-05-30 2005-09-13 J. Michael Seddon Catheter
EP1727474B1 (en) 2004-03-22 2009-10-14 Accessclosure, Inc. Apparatus for sealing a vascular puncture
US9289195B2 (en) 2003-06-04 2016-03-22 Access Closure, Inc. Auto-retraction apparatus and methods for sealing a vascular puncture
US20040249412A1 (en) 2003-06-04 2004-12-09 Snow Brent W. Apparatus and methods for puncture site closure
US20070093869A1 (en) 2003-06-20 2007-04-26 Medtronic Vascular, Inc. Device, system, and method for contracting tissue in a mammalian body
US7316706B2 (en) 2003-06-20 2008-01-08 Medtronic Vascular, Inc. Tensioning device, system, and method for treating mitral valve regurgitation
US8480706B2 (en) 2003-07-14 2013-07-09 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
ES2428967T3 (en) 2003-07-14 2013-11-12 W.L. Gore & Associates, Inc. tubular closure device patent foramen ovale (PFO) retention system
DE10335648A1 (en) 2003-07-30 2005-03-03 Eberhard-Karls-Universität Tübingen Sealing plug for an opening in a wall of a vessel or hollow organ
US8137364B2 (en) 2003-09-11 2012-03-20 Abbott Laboratories Articulating suturing device and method
WO2005027753A1 (en) 2003-09-19 2005-03-31 St. Jude Medical, Inc. Apparatus and methods for tissue gathering and securing
US20050075654A1 (en) 2003-10-06 2005-04-07 Brian Kelleher Methods and devices for soft tissue securement
US7931670B2 (en) 2003-10-15 2011-04-26 St. Jude Medical Puerto Rico Llc Tissue puncture closure device with automatic tamping
US8007514B2 (en) 2003-10-17 2011-08-30 St. Jude Medical Puerto Rico Llc Automatic suture locking device
US7361183B2 (en) 2003-10-17 2008-04-22 Ensure Medical, Inc. Locator and delivery device and method of use
US8852229B2 (en) 2003-10-17 2014-10-07 Cordis Corporation Locator and closure device and method of use
EP2213244A1 (en) 2003-10-24 2010-08-04 ev3 Endovascular, Inc. Patent foramen ovale closure system
US7731726B2 (en) 2003-12-03 2010-06-08 St. Jude Medical Puerto Rico Llc Suture based vascular closure apparatus and method incorporating a pre-tied knot
US20080097509A1 (en) * 2003-12-15 2008-04-24 Mordechay Beyar Biodegradable Closure Device
US7717929B2 (en) 2003-12-19 2010-05-18 Radi Medical Systems Ab Technique for securing a suture
US20050149117A1 (en) 2003-12-24 2005-07-07 Farhad Khosravi Apparatus and methods for delivering sealing materials during a percutaneous procedure to facilitate hemostasis
US20050245876A1 (en) 2003-12-24 2005-11-03 Accessclosure, Inc. Apparatus and methods for facilitating access through a puncture including sealing compound therein
US20070060950A1 (en) 2003-12-24 2007-03-15 Farhad Khosravi Apparatus and methods for delivering sealing materials during a percutaneous procedure to facilitate hemostasis
US7618427B2 (en) 2003-12-29 2009-11-17 Ethicon Endo-Surgery, Inc. Device and method for intralumenal anastomosis
US20050154401A1 (en) 2004-01-08 2005-07-14 Scimed Life Systems, Inc. Suturing device for implantable device
US7445596B2 (en) 2004-01-29 2008-11-04 Cannuflow, Inc. Atraumatic arthroscopic instrument sheath
EP1720595B1 (en) 2004-03-03 2011-05-11 C.R.Bard, Inc. Loop-tip catheter
US20050203550A1 (en) 2004-03-11 2005-09-15 Laufer Michael D. Surgical fastener
US9017374B2 (en) 2004-04-09 2015-04-28 Cardiva Medical, Inc. Device and method for sealing blood vessels
US20050267524A1 (en) 2004-04-09 2005-12-01 Nmt Medical, Inc. Split ends closure device
CA2563298A1 (en) 2004-05-07 2005-11-24 Nmt Medical, Inc. Catching mechanisms for tubular septal occluder
US20050256532A1 (en) 2004-05-12 2005-11-17 Asha Nayak Cardiovascular defect patch device and method
WO2005115521A1 (en) 2004-05-14 2005-12-08 Medtronic, Inc. Medical tubing connector assembly incorporating strain relief sleeve
US8590760B2 (en) 2004-05-25 2013-11-26 Abbott Vascular Inc. Surgical stapler
US7678135B2 (en) 2004-06-09 2010-03-16 Usgi Medical, Inc. Compressible tissue anchor assemblies
EP1611850A1 (en) 2004-06-28 2006-01-04 Cardio Life Research S.A. Occlusion and tight punction device for an anatomical structure
US7556632B2 (en) 2004-07-09 2009-07-07 Reza Zadno Device and method for repairing tissue
DE102004038823B3 (en) 2004-08-04 2006-03-30 Aesculap Ag & Co. Kg Implant for fixing adjacent bone plates
US8262693B2 (en) 2004-11-05 2012-09-11 Accessclosure, Inc. Apparatus and methods for sealing a vascular puncture
US7582104B2 (en) 2004-12-08 2009-09-01 Cardia, Inc. Daisy design for occlusion device
US8105352B2 (en) 2004-12-16 2012-01-31 Radi Medical Systems Ab Medical sealing device
US20060142784A1 (en) 2004-12-28 2006-06-29 Stavros Kontos Device and method for suturing internal structures puncture wounds
US7931671B2 (en) 2005-03-11 2011-04-26 Radi Medical Systems Ab Medical sealing device
US7344544B2 (en) 2005-03-28 2008-03-18 Cardica, Inc. Vascular closure system
US8177741B2 (en) 2005-04-12 2012-05-15 Cook Medical Technologies Llc Catheter with superelastic retention device
ES2623217T3 (en) 2005-04-22 2017-07-10 Access Closure, Inc. Apparatus for sealing a perforation in the tissue
US8002742B2 (en) 2005-04-22 2011-08-23 Accessclosure, Inc. Apparatus and methods for sealing a puncture in tissue
US7806856B2 (en) 2005-04-22 2010-10-05 Accessclosure, Inc. Apparatus and method for temporary hemostasis
US8088144B2 (en) 2005-05-04 2012-01-03 Ensure Medical, Inc. Locator and closure device and method of use
US7622628B2 (en) 2005-05-04 2009-11-24 Innovasa Corporation Hemostatic wire guided bandage and method of use
USD566272S1 (en) 2005-05-19 2008-04-08 Integrated Vascular Systems, Inc. Vessel closure device
US8926633B2 (en) 2005-06-24 2015-01-06 Abbott Laboratories Apparatus and method for delivering a closure element
US20060293698A1 (en) 2005-06-28 2006-12-28 Medtronic Vascular, Inc. Retainer device for mitral valve leaflets
US20080312686A1 (en) 2005-07-01 2008-12-18 Abbott Laboratories Antimicrobial closure element and closure element applier
USD611144S1 (en) 2006-06-28 2010-03-02 Abbott Laboratories Apparatus for delivering a closure element
US8007508B2 (en) 2005-07-01 2011-08-30 Cox John A System for tissue dissection and retraction
WO2007016349A3 (en) 2005-07-29 2007-06-07 Cvdevices Llc Devices and methods for percutaneous endo-ventricular reconstruction of the failing heart
US8029522B2 (en) 2005-08-05 2011-10-04 Ethicon Endo-Surgery, Inc. Method and apparatus for sealing a gastric opening
US20070060895A1 (en) 2005-08-24 2007-03-15 Sibbitt Wilmer L Jr Vascular closure methods and apparatuses
US8920442B2 (en) 2005-08-24 2014-12-30 Abbott Vascular Inc. Vascular opening edge eversion methods and apparatuses
US8758397B2 (en) 2005-08-24 2014-06-24 Abbott Vascular Inc. Vascular closure methods and apparatuses
US20070203507A1 (en) 2005-08-26 2007-08-30 G-Surge Medical Solutions, Inc. Suturing apparatus and methods
CA2621197A1 (en) 2005-09-01 2007-03-08 Cordis Corporation Patent foramen ovale closure method
US7846179B2 (en) 2005-09-01 2010-12-07 Ovalis, Inc. Suture-based systems and methods for treating septal defects
US8758375B2 (en) 2005-09-28 2014-06-24 Olympus Medical Systems Corp Method for suturing perforation
CN101495047B (en) 2005-10-05 2011-12-28 洛马林达大学医学中心 The vessel wound closure apparatus and method
US20070083231A1 (en) 2005-10-07 2007-04-12 Benjamin Lee Vascular closure
US20070083230A1 (en) 2005-10-07 2007-04-12 Alex Javois Left atrial appendage occlusion device
US20070112365A1 (en) 2005-11-15 2007-05-17 Applied Medical Resources Corporation Partial occlusion surgical guide clip
US7815659B2 (en) 2005-11-15 2010-10-19 Ethicon Endo-Surgery, Inc. Suture anchor applicator
US20070129755A1 (en) 2005-12-05 2007-06-07 Ovalis, Inc. Clip-based systems and methods for treating septal defects
EP1962695A1 (en) 2005-12-22 2008-09-03 NMT Medical, Inc. Catch members for occluder devices
US20070149996A1 (en) 2005-12-28 2007-06-28 Medtronic Vascular, Inc. Low profile filter
EP1971273B1 (en) 2006-01-09 2010-12-01 Cook Incorporated Patent foramen ovale closure device
US8162974B2 (en) 2006-02-02 2012-04-24 Boston Scientific Scimed, Inc. Occlusion apparatus, system, and method
US7625392B2 (en) 2006-02-03 2009-12-01 James Coleman Wound closure devices and methods
WO2007092323A1 (en) 2006-02-07 2007-08-16 Sutura, Inc. Reverse tapered guidewire and method of use
US20070225757A1 (en) 2006-03-22 2007-09-27 Radi Medical Systems Ab Closure device
US20070225756A1 (en) 2006-03-22 2007-09-27 Radi Medical Systems Ab Closure device and insertion assembly
US20070225758A1 (en) 2006-03-22 2007-09-27 Radi Medical Systems Ab Closure device
US20070225755A1 (en) 2006-03-22 2007-09-27 Radi Medical Systems Ab Closure device
US8808310B2 (en) 2006-04-20 2014-08-19 Integrated Vascular Systems, Inc. Resettable clip applier and reset tools
US20070265658A1 (en) 2006-05-12 2007-11-15 Aga Medical Corporation Anchoring and tethering system
US20080033459A1 (en) 2006-08-03 2008-02-07 Surgsolutions, Llp Suturing apparatus for closing tissue defects
US8758398B2 (en) 2006-09-08 2014-06-24 Integrated Vascular Systems, Inc. Apparatus and method for delivering a closure element
WO2008036384A3 (en) 2006-09-21 2008-07-24 Synecor Llc Stomach wall closure devices
US8172749B2 (en) 2006-09-28 2012-05-08 Cook Medical Technologies Llc Bolster assembly
US20080086075A1 (en) 2006-10-09 2008-04-10 Isik F Frank Vascular access devices and methods of use
US8029532B2 (en) 2006-10-11 2011-10-04 Cook Medical Technologies Llc Closure device with biomaterial patches
JP4584230B2 (en) 2006-11-14 2010-11-17 オリンパスメディカルシステムズ株式会社 Clipping device
DE102006056283A1 (en) 2006-11-29 2008-06-05 Biomagnetik Park Gmbh Occlusion device for closing left heart auricle of patient, has cladding bag provided with fillable opening at its proximal end and partially made of thermoplastic polyurethane, where bag is partially filled with non-degradable plastic
US20080281350A1 (en) 2006-12-13 2008-11-13 Biomerix Corporation Aneurysm Occlusion Devices
US20080177288A1 (en) 2007-01-19 2008-07-24 Carlson Mark A Remote Suturing Device
US9254124B2 (en) 2007-02-05 2016-02-09 Boston Scientific Scimed Inc. Self-orientating suture wound closure device
US7533790B1 (en) 2007-03-08 2009-05-19 Cardica, Inc. Surgical stapler
US8080034B2 (en) 2007-03-29 2011-12-20 St. Jude Medical, Inc. Vascular hemostasis device and deployment apparatus
US9545258B2 (en) 2007-05-17 2017-01-17 Boston Scientific Scimed, Inc. Tissue aperture securing and sealing apparatuses and related methods of use
WO2008147871A1 (en) 2007-05-25 2008-12-04 Wilson-Cook Medical, Inc. Medical devices, systems and methods for closing perforations
US20080300628A1 (en) 2007-06-01 2008-12-04 Abbott Laboratories Medical Devices
US7967842B2 (en) 2007-06-01 2011-06-28 Ethicon Endo-Surgery, Inc. Integrated securement and closure apparatus
US8226681B2 (en) 2007-06-25 2012-07-24 Abbott Laboratories Methods, devices, and apparatus for managing access through tissue
US8172871B2 (en) 2007-08-31 2012-05-08 Ken Christopher G M Closure medical device
US7875054B2 (en) 2007-10-01 2011-01-25 Boston Scientific Scimed, Inc. Connective tissue closure device and method
US8142490B2 (en) 2007-10-24 2012-03-27 Cordis Corporation Stent segments axially connected by thin film
US8016880B2 (en) * 2007-11-16 2011-09-13 Medtronic Vascular, Inc. Stent having spiral channel for drug delivery
US20090157101A1 (en) 2007-12-17 2009-06-18 Abbott Laboratories Tissue closure system and methods of use
US8893947B2 (en) 2007-12-17 2014-11-25 Abbott Laboratories Clip applier and methods of use
US7841502B2 (en) 2007-12-18 2010-11-30 Abbott Laboratories Modular clip applier
US20090187215A1 (en) 2007-12-19 2009-07-23 Abbott Laboratories Methods and apparatus to reduce a dimension of an implantable device in a smaller state
US8103327B2 (en) 2007-12-28 2012-01-24 Rhythmia Medical, Inc. Cardiac mapping catheter
JP5588359B2 (en) 2008-03-03 2014-09-10 アプライド メディカル リソーシーズ コーポレイション New fixing system of the balloon trocar
US9282965B2 (en) 2008-05-16 2016-03-15 Abbott Laboratories Apparatus and methods for engaging tissue
WO2009149474A1 (en) 2008-06-06 2009-12-10 Vital Access Corporation Tissue management methods, apparatus, and systems
EP2330985A4 (en) 2008-09-04 2015-11-18 Curaseal Inc Inflatable devices for enteric fistula treatment
DE102008053809A1 (en) 2008-10-29 2010-05-12 Medi-Globe Gmbh A surgical Fadenpositioniersystem for sealing an opening within a tissue wall
US8398676B2 (en) 2008-10-30 2013-03-19 Abbott Vascular Inc. Closure device
US8858594B2 (en) 2008-12-22 2014-10-14 Abbott Laboratories Curved closure device
US8323312B2 (en) 2008-12-22 2012-12-04 Abbott Laboratories Closure device
US9173644B2 (en) 2009-01-09 2015-11-03 Abbott Vascular Inc. Closure devices, systems, and methods
US20100179589A1 (en) 2009-01-09 2010-07-15 Abbott Vascular Inc. Rapidly eroding anchor
US20100179567A1 (en) 2009-01-09 2010-07-15 Abbott Vascular Inc. Closure devices, systems, and methods
US9414820B2 (en) 2009-01-09 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US9486191B2 (en) 2009-01-09 2016-11-08 Abbott Vascular, Inc. Closure devices
US9089311B2 (en) 2009-01-09 2015-07-28 Abbott Vascular Inc. Vessel closure devices and methods
US20110218568A1 (en) 2009-01-09 2011-09-08 Voss Laveille K Vessel closure devices, systems, and methods
US20100185234A1 (en) 2009-01-16 2010-07-22 Abbott Vascular Inc. Closure devices, systems, and methods
US8905937B2 (en) 2009-02-26 2014-12-09 Integrated Vascular Systems, Inc. Methods and apparatus for locating a surface of a body lumen
US20110054492A1 (en) 2009-08-26 2011-03-03 Abbott Laboratories Medical device for repairing a fistula
US20110082495A1 (en) 2009-10-02 2011-04-07 Ruiz Carlos E Apparatus And Methods For Excluding The Left Atrial Appendage
US8303624B2 (en) 2010-03-15 2012-11-06 Abbott Cardiovascular Systems, Inc. Bioabsorbable plug
US8758399B2 (en) 2010-08-02 2014-06-24 Abbott Cardiovascular Systems, Inc. Expandable bioabsorbable plug apparatus and method
US8603116B2 (en) 2010-08-04 2013-12-10 Abbott Cardiovascular Systems, Inc. Closure device with long tines
US8821534B2 (en) 2010-12-06 2014-09-02 Integrated Vascular Systems, Inc. Clip applier having improved hemostasis and methods of use
US8821529B2 (en) 2011-03-25 2014-09-02 Aga Medical Corporation Device and method for occluding a septal defect
US9332976B2 (en) 2011-11-30 2016-05-10 Abbott Cardiovascular Systems, Inc. Tissue closure device

Patent Citations (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US31855A (en) * 1861-03-26 G Weiland Straw-carrier for threshing-machines
US1088393A (en) * 1913-09-20 1914-02-24 Oscar E Backus Button.
US1331401A (en) * 1919-09-12 1920-02-17 Summers Henry Clay Button-fastening
US1480935A (en) * 1922-04-03 1924-01-15 Dora P Gleason Barrette
US2583625A (en) * 1946-10-29 1952-01-29 Thomas & Betts Corp Method of and tool for crimping tubes
US2969887A (en) * 1959-04-08 1961-01-31 American Thermos Products Comp Threaded pouring lip stopper combination for vacuum bottle
US3015403A (en) * 1959-04-08 1962-01-02 American Thermos Products Comp Threaded stopper expanding pouring lip combination for vacuum bottle
US3120230A (en) * 1960-10-24 1964-02-04 Jack H Sanders Surgical clamp
US3494533A (en) * 1966-10-10 1970-02-10 United States Surgical Corp Surgical stapler for stitching body organs
US3939820A (en) * 1974-10-29 1976-02-24 Datascope Corporation Single-chamber, multi-section balloon for cardiac assistance
US4189808A (en) * 1978-09-20 1980-02-26 Brown Theodore G Retainer and closure for a garbage can liner bag
US4428376A (en) * 1980-05-02 1984-01-31 Ethicon Inc. Plastic surgical staple
US4368736A (en) * 1980-11-17 1983-01-18 Kaster Robert L Anastomotic fitting
US4724840A (en) * 1982-02-03 1988-02-16 Ethicon, Inc. Surgical fastener applier with rotatable front housing and laterally extending curved needle for guiding a flexible pusher
US6030413A (en) * 1983-12-09 2000-02-29 Endovascular Technologies, Inc. Artificial graft and implantation method
US4635634A (en) * 1985-07-12 1987-01-13 Santos Manuel V Surgical clip applicator system
US4890612A (en) * 1987-02-17 1990-01-02 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
US4719917A (en) * 1987-02-17 1988-01-19 Minnesota Mining And Manufacturing Company Surgical staple
US5510115A (en) * 1987-11-16 1996-04-23 Baxter Travenol Laboratories, Inc. Method and composition for administration of beneficial agent by controlled dissolution
US4902508A (en) * 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US4983176A (en) * 1989-03-06 1991-01-08 University Of New Mexico Deformable plastic surgical clip
US5078731A (en) * 1990-06-05 1992-01-07 Hayhurst John O Suture clip
US5601602A (en) * 1990-10-01 1997-02-11 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5275616A (en) * 1990-10-01 1994-01-04 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5591205A (en) * 1990-10-01 1997-01-07 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5275616B1 (en) * 1990-10-01 1996-01-23 Quinton Instr Insertion assembly and method of inserting a vessel plug into the body of a patient
US5716375A (en) * 1990-10-01 1998-02-10 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5392978A (en) * 1991-02-08 1995-02-28 United States Surgical Corporation Surgical staple and endoscopic stapler
US5281422A (en) * 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US5282827A (en) * 1991-11-08 1994-02-01 Kensey Nash Corporation Hemostatic puncture closure system and method of use
US5176648A (en) * 1991-12-13 1993-01-05 Unisurge, Inc. Introducer assembly and instrument for use therewith
US5871525A (en) * 1992-04-13 1999-02-16 Ep Technologies, Inc. Steerable ablation catheter system
US5282808A (en) * 1992-05-26 1994-02-01 Origin Medsystems, Inc. Closure prevention apparatus for surgical clip applier
US5383897A (en) * 1992-10-19 1995-01-24 Shadyside Hospital Method and apparatus for closing blood vessel punctures
US5860991A (en) * 1992-12-10 1999-01-19 Perclose, Inc. Method for the percutaneous suturing of a vascular puncture site
EP0621032A1 (en) * 1993-04-23 1994-10-26 Ciba-Geigy Ag Controlled release drug delivery device
US5383896A (en) * 1993-05-25 1995-01-24 Gershony; Gary Vascular sealing device
US5486195A (en) * 1993-07-26 1996-01-23 Myers; Gene Method and apparatus for arteriotomy closure
US5871501A (en) * 1994-01-18 1999-02-16 Datascope Investment Corp. Guide wire with releasable barb anchor
US5593412A (en) * 1994-03-01 1997-01-14 Cordis Corporation Stent delivery method and apparatus
US6171329B1 (en) * 1994-12-19 2001-01-09 Gore Enterprise Holdings, Inc. Self-expanding defect closure device and method of making and using
US5720755A (en) * 1995-01-18 1998-02-24 Dakov; Pepi Tubular suturing device and methods of use
US6984238B2 (en) * 1995-02-24 2006-01-10 Gifford Iii Hanson S Devices and methods for performing avascular anastomosis
US5713899A (en) * 1995-04-27 1998-02-03 Societe Jbs Sa Cervical cage designed for the performance of intersomatic arthrodesis
US5871474A (en) * 1995-05-19 1999-02-16 General Surgical Innovations, Inc. Screw-type skin seal with inflatable membrane
US5709224A (en) * 1995-06-07 1998-01-20 Radiotherapeutics Corporation Method and device for permanent vessel occlusion
US6013084A (en) * 1995-06-30 2000-01-11 Target Therapeutics, Inc. Stretch resistant vaso-occlusive coils (II)
US6238705B1 (en) * 1995-07-28 2001-05-29 Advanced Poymer Systems, Inc. Bioerodible porous compositions
US6024756A (en) * 1996-03-22 2000-02-15 Scimed Life Systems, Inc. Method of reversibly closing a septal defect
US6010517A (en) * 1996-04-10 2000-01-04 Baccaro; Jorge Alberto Device for occluding abnormal vessel communications
US7169158B2 (en) * 1996-07-23 2007-01-30 Tyco Healthcare Group Lp Anastomosis instrument and method for performing same
US5855312A (en) * 1996-07-25 1999-01-05 Toledano; Haviv Flexible annular stapler for closed surgery of hollow organs
US5868763A (en) * 1996-09-16 1999-02-09 Guidant Corporation Means and methods for performing an anastomosis
US5873876A (en) * 1996-09-23 1999-02-23 Christy; William J. Surgical loop delivery device and method
US6679904B2 (en) * 1996-10-17 2004-01-20 Malachy Gleeson Device for closure of puncture wound
US5861003A (en) * 1996-10-23 1999-01-19 The Cleveland Clinic Foundation Apparatus and method for occluding a defect or aperture within body surface
US5868755A (en) * 1997-01-16 1999-02-09 Atrion Medical Products, Inc. Sheath retractor mechanism and method
US6022372A (en) * 1997-02-11 2000-02-08 X-Site, L.L.C. Arterial stapling device
US5861005A (en) * 1997-02-11 1999-01-19 X-Site, L.L.C. Arterial stapling device
US6193708B1 (en) * 1997-08-05 2001-02-27 Scimed Life Systems, Inc. Detachable aneurysm neck bridge (I)
US6174322B1 (en) * 1997-08-08 2001-01-16 Cardia, Inc. Occlusion device for the closure of a physical anomaly such as a vascular aperture or an aperture in a septum
US6024750A (en) * 1997-08-14 2000-02-15 United States Surgical Ultrasonic curved blade
US5858082A (en) * 1997-09-15 1999-01-12 Cruz; Hector Gonzalo Self-interlocking reinforcement fibers
US6015815A (en) * 1997-09-26 2000-01-18 Abbott Laboratories Tetrazole-containing rapamycin analogs with shortened half-lives
US6030364A (en) * 1997-10-03 2000-02-29 Boston Scientific Corporation Apparatus and method for percutaneous placement of gastro-intestinal tubes
US6455053B1 (en) * 1997-10-09 2002-09-24 Ssp Co., Ltd. Quickly soluble solid preparations
US6171277B1 (en) * 1997-12-01 2001-01-09 Cordis Webster, Inc. Bi-directional control handle for steerable catheter
US6193734B1 (en) * 1998-01-23 2001-02-27 Heartport, Inc. System for performing vascular anastomoses
US6514280B1 (en) * 1998-04-02 2003-02-04 Salviac Limited Delivery catheter
US6989016B2 (en) * 1998-07-22 2006-01-24 Medtronic Angiolink, Inc. Vascular suction cannula, dilator and surgical stapler
US6334865B1 (en) * 1998-08-04 2002-01-01 Fusion Medical Technologies, Inc. Percutaneous tissue track closure assembly and method
US6517569B2 (en) * 1998-09-14 2003-02-11 Endocare, Inc. Insertion device for stents and methods for use
US6676671B2 (en) * 1998-09-15 2004-01-13 United States Surgical Stapling apparatus and method for heart valve replacement
US6676685B2 (en) * 1999-02-22 2004-01-13 Tyco Healthcare Group Lp Arterial hole closure apparatus
US7001400B1 (en) * 1999-03-04 2006-02-21 Abbott Laboratories Articulating suturing device and method
US6179849B1 (en) * 1999-06-10 2001-01-30 Vascular Innovations, Inc. Sutureless closure for connecting a bypass graft to a target vessel
US20020026216A1 (en) * 1999-10-13 2002-02-28 Grimes Randall Y. Devices and methods for percutaneous mitral valve repair
US6849078B2 (en) * 1999-11-18 2005-02-01 Ovesco Endoscopy, Gmbh Apparatus and method for compressing body tissue
US6689147B1 (en) * 2000-06-13 2004-02-10 J. Kenneth Koster, Jr. Anastomosis punch device and method
US20020022822A1 (en) * 2000-07-14 2002-02-21 Cragg Andrew H. Sheath-mounted arterial plug delivery device
US6837893B2 (en) * 2000-09-01 2005-01-04 Onux Medical, Inc. Multi-fastener surgical apparatus and method
US6348064B1 (en) * 2000-09-01 2002-02-19 Angiolink Corporation Wound site management and wound closure device
US6506210B1 (en) * 2000-09-01 2003-01-14 Angiolink Corporation Wound site management and wound closure device
US6517555B1 (en) * 2000-09-05 2003-02-11 Clear Sight, Inc. Method for treating presbyopia
US7169164B2 (en) * 2000-09-21 2007-01-30 Atritech, Inc. Apparatus for implanting devices in atrial appendages
US6508828B1 (en) * 2000-11-03 2003-01-21 Radi Medical Systems Ab Sealing device and wound closure device
US7001398B2 (en) * 2000-12-07 2006-02-21 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US6846319B2 (en) * 2000-12-14 2005-01-25 Core Medical, Inc. Devices for sealing openings through tissue and apparatus and methods for delivering them
US6837906B2 (en) * 2001-08-03 2005-01-04 Ensure Medical, Inc. Lung assist apparatus and methods for use
US7163551B2 (en) * 2001-08-09 2007-01-16 Thomas Anthony Surgical stapling device
US6989003B2 (en) * 2001-08-31 2006-01-24 Conmed Corporation Obturator and cannula for a trocar adapted for ease of insertion and removal
US6695867B2 (en) * 2002-02-21 2004-02-24 Integrated Vascular Systems, Inc. Plunger apparatus and methods for delivering a closure device
US20050169974A1 (en) * 2002-05-08 2005-08-04 Radi Medical Systems Ab Dissolvable medical sealing device
US7322995B2 (en) * 2002-09-13 2008-01-29 Damage Control Surgical Technologies, Inc. Method and apparatus for vascular and visceral clipping
US20140005692A1 (en) * 2003-01-30 2014-01-02 Integrated Vascular Systems, Inc. Methods of use of a clip applier
US7331979B2 (en) * 2003-06-04 2008-02-19 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
US7316704B2 (en) * 2003-06-04 2008-01-08 Accessclosure, Inc. Occlusion member and tensioner apparatus and methods of their use for sealing a vascular puncture
US7326230B2 (en) * 2003-10-23 2008-02-05 Sundaram Ravikumar Vascular sealing device and method of use
US20070027525A1 (en) * 2003-11-19 2007-02-01 Neovasc Medical Ltd Vascular implant
US20070282373A1 (en) * 2003-11-25 2007-12-06 Mark Ashby Hemostatic Pressure Plug
US20050152949A1 (en) * 2004-01-13 2005-07-14 Orthobiologica, Inc. Drug delivery to a joint
US7645285B2 (en) * 2004-05-26 2010-01-12 Idx Medical, Ltd Apparatus and methods for occluding a hollow anatomical structure
US20060047313A1 (en) * 2004-08-27 2006-03-02 Accessclosure, Inc. Apparatus and methods for facilitating hemostasis within a vascular puncture
US7335220B2 (en) * 2004-11-05 2008-02-26 Access Closure, Inc. Apparatus and methods for sealing a vascular puncture
US20080114395A1 (en) * 2005-01-14 2008-05-15 Radi Medical Systems Ab Closure Device
US20070027476A1 (en) * 2005-02-07 2007-02-01 Regen Biologics, Inc. System and method for all-inside suture fixation for implant attachment and soft tissue repair
US20130006274A1 (en) * 2005-07-01 2013-01-03 Abbott Laboratories Clip applier and methods of use
US20070172430A1 (en) * 2006-01-20 2007-07-26 Nastech Pharmaceutical Company Inc. Dry powder compositions for rna influenza therapeutics
US20070275036A1 (en) * 2006-05-18 2007-11-29 Celldyne Biopharma, Llc Avian follistatin product
US20140018850A1 (en) * 2006-06-28 2014-01-16 Abbott Laboratories Vessel closure device
US20090171388A1 (en) * 2007-10-31 2009-07-02 Vipul Bhupendra Dave Vascular closure device
US20090216267A1 (en) * 2008-02-26 2009-08-27 Boston Scientific Scimed, Inc. Closure device with rapidly dissolving anchor
US20090227938A1 (en) * 2008-03-05 2009-09-10 Insitu Therapeutics, Inc. Wound Closure Devices, Methods of Use, and Kits
US20100042144A1 (en) * 2008-08-12 2010-02-18 Steven Bennett Medical Device for Wound Closure and Method of Use

Cited By (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8758400B2 (en) 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Closure system and methods of use
US7901428B2 (en) 2000-01-05 2011-03-08 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US8758396B2 (en) 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US7931669B2 (en) 2000-01-05 2011-04-26 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US9579091B2 (en) 2000-01-05 2017-02-28 Integrated Vascular Systems, Inc. Closure system and methods of use
US8956388B2 (en) 2000-01-05 2015-02-17 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant
US9050087B2 (en) 2000-01-05 2015-06-09 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US9060769B2 (en) 2000-09-08 2015-06-23 Abbott Vascular Inc. Surgical stapler
US8784447B2 (en) 2000-09-08 2014-07-22 Abbott Vascular Inc. Surgical stapler
US9402625B2 (en) 2000-09-08 2016-08-02 Abbott Vascular Inc. Surgical stapler
US9089674B2 (en) 2000-10-06 2015-07-28 Integrated Vascular Systems, Inc. Apparatus and methods for positioning a vascular sheath
US8597325B2 (en) 2000-12-07 2013-12-03 Integrated Vascular Systems, Inc. Apparatus and methods for providing tactile feedback while delivering a closure device
US7879071B2 (en) 2000-12-07 2011-02-01 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US9320522B2 (en) 2000-12-07 2016-04-26 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8236026B2 (en) 2000-12-07 2012-08-07 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8257390B2 (en) 2000-12-07 2012-09-04 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US9554786B2 (en) 2000-12-07 2017-01-31 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8690910B2 (en) 2000-12-07 2014-04-08 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8182497B2 (en) 2000-12-07 2012-05-22 Integrated Vascular Systems, Inc. Closure device
US8128644B2 (en) 2000-12-07 2012-03-06 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US9585646B2 (en) 2000-12-07 2017-03-07 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7887555B2 (en) 2000-12-07 2011-02-15 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8603136B2 (en) 2000-12-07 2013-12-10 Integrated Vascular Systems, Inc. Apparatus and methods for providing tactile feedback while delivering a closure device
US8486108B2 (en) 2000-12-07 2013-07-16 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8486092B2 (en) 2000-12-07 2013-07-16 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7918873B2 (en) 2001-06-07 2011-04-05 Abbott Vascular Inc. Surgical staple
US8728119B2 (en) 2001-06-07 2014-05-20 Abbott Vascular Inc. Surgical staple
US8007512B2 (en) 2002-02-21 2011-08-30 Integrated Vascular Systems, Inc. Plunger apparatus and methods for delivering a closure device
US8579932B2 (en) 2002-02-21 2013-11-12 Integrated Vascular Systems, Inc. Sheath apparatus and methods for delivering a closure device
US9498196B2 (en) 2002-02-21 2016-11-22 Integrated Vascular Systems, Inc. Sheath apparatus and methods for delivering a closure device
US8469995B2 (en) 2002-06-04 2013-06-25 Abbott Vascular Inc. Blood vessel closure clip and delivery device
US8192459B2 (en) 2002-06-04 2012-06-05 Abbott Vascular Inc. Blood vessel closure clip and delivery device
US9295469B2 (en) 2002-06-04 2016-03-29 Abbott Vascular Inc. Blood vessel closure clip and delivery device
US8585836B2 (en) 2002-12-31 2013-11-19 Integrated Vascular Systems, Inc. Methods for manufacturing a clip and clip
US8202283B2 (en) 2002-12-31 2012-06-19 Integrated Vascular Systems, Inc. Methods for manufacturing a clip and clip
US8926656B2 (en) 2003-01-30 2015-01-06 Integated Vascular Systems, Inc. Clip applier and methods of use
US8398656B2 (en) 2003-01-30 2013-03-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8529587B2 (en) 2003-01-30 2013-09-10 Integrated Vascular Systems, Inc. Methods of use of a clip applier
US9271707B2 (en) 2003-01-30 2016-03-01 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8202294B2 (en) 2003-01-30 2012-06-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8202293B2 (en) 2003-01-30 2012-06-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US9398914B2 (en) 2003-01-30 2016-07-26 Integrated Vascular Systems, Inc. Methods of use of a clip applier
US9241706B2 (en) 2003-09-15 2016-01-26 Abbott Laboratories Suture locking device and methods
US8590760B2 (en) 2004-05-25 2013-11-26 Abbott Vascular Inc. Surgical stapler
US8926633B2 (en) 2005-06-24 2015-01-06 Abbott Laboratories Apparatus and method for delivering a closure element
US9050068B2 (en) 2005-07-01 2015-06-09 Abbott Laboratories Clip applier and methods of use
US8518057B2 (en) 2005-07-01 2013-08-27 Abbott Laboratories Clip applier and methods of use
US8313497B2 (en) 2005-07-01 2012-11-20 Abbott Laboratories Clip applier and methods of use
US9456811B2 (en) 2005-08-24 2016-10-04 Abbott Vascular Inc. Vascular closure methods and apparatuses
US8920442B2 (en) 2005-08-24 2014-12-30 Abbott Vascular Inc. Vascular opening edge eversion methods and apparatuses
US8808310B2 (en) 2006-04-20 2014-08-19 Integrated Vascular Systems, Inc. Resettable clip applier and reset tools
US8556930B2 (en) 2006-06-28 2013-10-15 Abbott Laboratories Vessel closure device
US8758398B2 (en) 2006-09-08 2014-06-24 Integrated Vascular Systems, Inc. Apparatus and method for delivering a closure element
US8226681B2 (en) 2007-06-25 2012-07-24 Abbott Laboratories Methods, devices, and apparatus for managing access through tissue
US8876861B2 (en) 2007-09-12 2014-11-04 Transluminal Technologies, Inc. Closure device, deployment apparatus, and method of deploying a closure device
US9456816B2 (en) 2007-09-12 2016-10-04 Transluminal Technologies, Llc Closure device, deployment apparatus, and method of deploying a closure device
US8893947B2 (en) 2007-12-17 2014-11-25 Abbott Laboratories Clip applier and methods of use
US8672953B2 (en) 2007-12-17 2014-03-18 Abbott Laboratories Tissue closure system and methods of use
US8820602B2 (en) 2007-12-18 2014-09-02 Abbott Laboratories Modular clip applier
US9282965B2 (en) 2008-05-16 2016-03-15 Abbott Laboratories Apparatus and methods for engaging tissue
US8398676B2 (en) 2008-10-30 2013-03-19 Abbott Vascular Inc. Closure device
US8657852B2 (en) 2008-10-30 2014-02-25 Abbott Vascular Inc. Closure device
US9241696B2 (en) 2008-10-30 2016-01-26 Abbott Vascular Inc. Closure device
US8323312B2 (en) 2008-12-22 2012-12-04 Abbott Laboratories Closure device
US8858594B2 (en) 2008-12-22 2014-10-14 Abbott Laboratories Curved closure device
US9314230B2 (en) 2009-01-09 2016-04-19 Abbott Vascular Inc. Closure device with rapidly eroding anchor
US9486191B2 (en) 2009-01-09 2016-11-08 Abbott Vascular, Inc. Closure devices
US9414820B2 (en) 2009-01-09 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US9173644B2 (en) 2009-01-09 2015-11-03 Abbott Vascular Inc. Closure devices, systems, and methods
US9089311B2 (en) 2009-01-09 2015-07-28 Abbott Vascular Inc. Vessel closure devices and methods
US9414824B2 (en) 2009-01-16 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US8905937B2 (en) 2009-02-26 2014-12-09 Integrated Vascular Systems, Inc. Methods and apparatus for locating a surface of a body lumen
US9585647B2 (en) 2009-08-26 2017-03-07 Abbott Laboratories Medical device for repairing a fistula
US8303624B2 (en) 2010-03-15 2012-11-06 Abbott Cardiovascular Systems, Inc. Bioabsorbable plug
US9839417B2 (en) * 2010-06-08 2017-12-12 Essential Medical, Inc. Deployment instrument for closure device for percutaneously sealing punctures
US20150068009A1 (en) * 2010-06-08 2015-03-12 Essential Medical Llc Deployment instrument for closure device for percutaneously sealing punctures
US8758399B2 (en) 2010-08-02 2014-06-24 Abbott Cardiovascular Systems, Inc. Expandable bioabsorbable plug apparatus and method
US8603116B2 (en) 2010-08-04 2013-12-10 Abbott Cardiovascular Systems, Inc. Closure device with long tines
KR101533898B1 (en) * 2010-11-02 2015-07-03 트랜스루미널 테크놀로지스, 엘엘씨 Closure device, deployment apparatus, and method of deploying a closure device
WO2012061486A3 (en) * 2010-11-02 2012-07-12 Transluminal Technologies, Inc. Closure device, deployment apparatus, and method of deploying a closure device
US9155530B2 (en) 2010-11-09 2015-10-13 Transluminal Technologies, Llc Specially designed magnesium-aluminum alloys and medical uses thereof in a hemodynamic environment
US8821534B2 (en) 2010-12-06 2014-09-02 Integrated Vascular Systems, Inc. Clip applier having improved hemostasis and methods of use
US9468431B2 (en) 2011-02-26 2016-10-18 Abbott Cardiovascular Systems, Inc. Hinged tissue support device
US9149265B2 (en) 2011-02-26 2015-10-06 Abbott Cardiovascular Systems, Inc. Hinged tissue support device
US9149276B2 (en) 2011-03-21 2015-10-06 Abbott Cardiovascular Systems, Inc. Clip and deployment apparatus for tissue closure
US9055932B2 (en) * 2011-08-26 2015-06-16 Abbott Cardiovascular Systems, Inc. Suture fastener combination device
US20130053884A1 (en) * 2011-08-26 2013-02-28 Abbott Cardiovascular Systems, Inc. Suture fastener combination device
US20150100083A1 (en) * 2011-10-25 2015-04-09 Essential Medical, Inc. Surgically closing percutaneously punctures
EP3092953A1 (en) * 2011-10-25 2016-11-16 Essential Medical, Inc. Surgically closing percutaneously punctures
US9332976B2 (en) 2011-11-30 2016-05-10 Abbott Cardiovascular Systems, Inc. Tissue closure device
US9138214B2 (en) 2012-03-02 2015-09-22 Abbott Cardiovascular Systems, Inc. Suture securing systems, devices and methods
US9757106B2 (en) 2012-12-03 2017-09-12 Cook Medical Technologies Llc Degradable expanding closure plug
US9364209B2 (en) 2012-12-21 2016-06-14 Abbott Cardiovascular Systems, Inc. Articulating suturing device
US20140277114A1 (en) * 2013-03-15 2014-09-18 Essential Medical, Inc. Vascular closure device with occlusion balloon guidewire
US9301746B2 (en) 2013-10-11 2016-04-05 Abbott Cardiovascular Systems, Inc. Suture-based closure with hemostatic tract plug
US9757108B2 (en) 2013-10-11 2017-09-12 Abbott Cardiovascular Systems, Inc. Suture-based closure with hemostatic tract plug
US9861410B2 (en) 2016-05-06 2018-01-09 Medos International Sarl Methods, devices, and systems for blood flow

Also Published As

Publication number Publication date Type
US20140364903A1 (en) 2014-12-11 application
US9314230B2 (en) 2016-04-19 grant

Similar Documents

Publication Publication Date Title
US6719777B2 (en) Closure device and methods for making and using them
US5860991A (en) Method for the percutaneous suturing of a vascular puncture site
US6042601A (en) Apparatus for vascular hole closure
US7182771B1 (en) Vascular couplers, techniques, methods, and accessories
EP0941698B1 (en) Suturing device for sealing an opening in a blood vessel
US5370660A (en) Apparatus and method for delivering a vessel plug into the body of a patient
US20080065152A1 (en) Apparatus and method for delivering a closure element
US20020026208A1 (en) Apparatus and methods for delivering a closure device
US20100179571A1 (en) Closure devices, systems, and methods
US20020072768A1 (en) Apparatus and methods for providing tactile feedback while delivering a closure device
US6641592B1 (en) System for wound closure
US7662161B2 (en) Vascular hole closure device
US20060100664A1 (en) Apparatus and methods for sealing a vascular puncture
US5868762A (en) Percutaneous hemostatic suturing device and method
US20090062847A1 (en) Closure medical device
US20090157101A1 (en) Tissue closure system and methods of use
US20120271337A1 (en) Occluder For Occluding an Atrial Appendage and Production Process Therefor
US20070129755A1 (en) Clip-based systems and methods for treating septal defects
US20060265010A1 (en) Suture locking device and methods
US6726696B1 (en) Patches and collars for medical applications and methods of use
US20090143808A1 (en) Guided Tissue Cutting Device, Method of Use and Kits Therefor
US20070203506A1 (en) Vascular closure methods and apparatuses
US6949107B2 (en) Injection method for locating vessel lumen
US20080300628A1 (en) Medical Devices
US5160341A (en) Resorbable urethral stent and apparatus for its insertion

Legal Events

Date Code Title Description
AS Assignment

Owner name: ABBOTT VASCULAR INC., CALIFORNIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:ROORDA, WOUTER E.;VOSS, LAVEILLE K.;MCCRYSTLE, KELLY J.;AND OTHERS;REEL/FRAME:023754/0382

Effective date: 20100107