US20090142340A1 - Optimized Fc Variants and Methods for Their Generation - Google Patents

Optimized Fc Variants and Methods for Their Generation Download PDF

Info

Publication number
US20090142340A1
US20090142340A1 US11/927,507 US92750707A US2009142340A1 US 20090142340 A1 US20090142340 A1 US 20090142340A1 US 92750707 A US92750707 A US 92750707A US 2009142340 A1 US2009142340 A1 US 2009142340A1
Authority
US
United States
Prior art keywords
antibody
fc
i332e
immunoadhesin
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11/927,507
Inventor
Gregory Alan Lazar
Arthur J. Chirino
Wei Dang
John R. Desjarlais
Stephen Kohl Doberstein
Robert J. Hayes
Sher Bahadur Karki
Omid Vafa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xencor Inc
Original Assignee
Xencor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US36084302P priority Critical
Priority to US38419702P priority
Priority to US41443302P priority
Priority to US44230103P priority
Priority to US10/379,392 priority patent/US20040110226A1/en
Priority to US46760603P priority
Priority to US47783903P priority
Priority to US10/672,280 priority patent/US20040132101A1/en
Priority to US10/822,231 priority patent/US7317091B2/en
Application filed by Xencor Inc filed Critical Xencor Inc
Priority to US11/927,507 priority patent/US20090142340A1/en
Publication of US20090142340A1 publication Critical patent/US20090142340A1/en
Application status is Abandoned legal-status Critical

Links