US20090098214A1 - Skin-revitalizing cosmetic composition - Google Patents

Skin-revitalizing cosmetic composition Download PDF

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Publication number
US20090098214A1
US20090098214A1 US12/051,987 US5198708A US2009098214A1 US 20090098214 A1 US20090098214 A1 US 20090098214A1 US 5198708 A US5198708 A US 5198708A US 2009098214 A1 US2009098214 A1 US 2009098214A1
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US
United States
Prior art keywords
skin
revitalizing
dissolved
cosmetic composition
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12/051,987
Inventor
Teruyuki NANBU
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ASKA Corp Co Ltd
Original Assignee
ASKA Corp Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2007263907A priority Critical patent/JP2009091298A/en
Priority to JP2007-263907 priority
Application filed by ASKA Corp Co Ltd filed Critical ASKA Corp Co Ltd
Assigned to ASKA CORPORATION CO., LTD. reassignment ASKA CORPORATION CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: NANBU, TERUYUKI
Publication of US20090098214A1 publication Critical patent/US20090098214A1/en
Application status is Abandoned legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells

Abstract

The invention provides a skin-revitalizing cosmetic composition for alleviating or eliminating skin problems such as dry skin, wrinkles, and age spots, the composition containing a skin-revitalizing agent at high concentration. The skin-revitalizing cosmetic composition contains a skin-revitalizing agent selected from the group consisting of aloe extract, placenta extract, hydrolyzed elastin, hydrolyzed collagen, and sodium hyaluronate, wherein the skin-revitalizing agent is in the form of nanoparticles obtained through a nanoparticle-forming treatment.

Description

    BACKGROUND OF THE INVENTION
  • 1. Field of the Invention
  • The present invention relates to a cosmetic composition, and more particularly to a skin-revitalizing cosmetic composition for alleviating or eliminating skin problems such as dry skin, wrinkles, and age spots.
  • 2. Background Art
  • There have been well known cosmetic products containing a skin-revitalizing agent for alleviating or eliminating skin problems such as dry skin, wrinkles, and age spots. For example, Japanese Patent Application Laid-Open (kokai) No. 2005-53842 discloses a cosmetic product containing an aloe extract; Japanese Patent Application Laid-Open (kokai) No. 2001-72567 discloses a cosmetic product containing a placenta extract; Japanese Patent Application Laid-Open (kokai) No. 2006-131557 discloses a cosmetic product containing hydrolyzed elastin; Japanese Patent Application Laid-Open (kokai) No. 2003-300854 discloses a cosmetic product containing hydrolyzed collagen; and Japanese Patent Application Laid-Open (kokai) No. H05-345717 discloses a cosmetic product containing sodium hyaluronate.
  • However, such a skin-revitalizing agent is difficult to dissolve in water, and thus can only be incorporated into a currently employed cosmetic product in an amount of up to 1 wt. % at most. Therefore, a cosmetic product containing such a skin-revitalizing agent fails to satisfactorily exhibit the effect of the agent.
  • SUMMARY OF THE INVENTION
  • In view of the foregoing, an object of the present invention is to provide a cosmetic composition which can contain such a skin-revitalizing agent at a high concentration, thereby attaining an improved skin-revitalizing effect.
  • The present inventors have conducted extensive studies on the aforementioned skin-revitalizing agents, and as a result have found that when a skin-revitalizing agent is subjected to a treatment for forming nanoparticles (hereinafter the treatment may be referred to as a “nanoparticle-forming treatment”), and then the thus-formed nanoparticles of the agent are incorporated into a cosmetic composition, the agent concentration of the cosmetic composition can be increased to more than 1 wt. %. The present invention has been accomplished on the basis of this finding.
  • Accordingly, the present invention provides a skin-revitalizing cosmetic composition containing a skin-revitalizing agent selected from the group consisting of aloe extract, placenta extract, hydrolyzed elastin, hydrolyzed collagen, and sodium hyaluronate, wherein the skin-revitalizing agent is in the form of nanoparticles obtained through a nanoparticle-forming treatment.
  • According to the present invention, since a skin-revitalizing agent can be incorporated into a cosmetic composition at a high concentration, a further improved skin-revitalizing effect of the composition can be obtained.
  • DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS
  • The present invention will next be described in more detail.
  • The skin-revitalizing cosmetic composition of the present invention contains a skin-revitalizing agent selected from the group consisting of aloe extract, placenta extract, hydrolyzed elastin, hydrolyzed collagen, and sodium hyaluronate, wherein the skin-revitalizing agent is in the form of nanoparticles obtained through a nanoparticle-forming treatment.
  • Such a skin-revitalizing agent itself is well known in the art, and thus detailed descriptions thereof are omitted.
  • In the present invention, such a skin-revitalizing agent is subjected to a nanoparticle-forming treatment, and then incorporated into a cosmetic composition. The nanoparticle-forming treatment of a skin-revitalizing agent may be carried out by means of a commercially available Nanomizer (e.g., Nanomaker, product of Nanomax).
  • Specifically, when a skin-revitalizing agent is dispersed in water, and the resultant aqueous dispersion is subjected to a nanoparticle-forming treatment, the skin-revitalizing agent can be formed into nanoparticles having a size (diameter) of 10 to 150 nm. The thus-formed nanoparticles of the skin-revitalizing agent can be incorporated into an aqueous cosmetic composition at a high concentration; i.e., more than 1 wt. % (generally more than 1 wt. % and up to 10 wt. %).
  • The skin-revitalizing cosmetic composition of the present invention which contains, as an essential component, nanoparticles of a skin-revitalizing agent formed through the aforementioned treatment may also contain additional ingredients as additives. Examples of the additives include ceramide and royal jelly extract.
  • EXAMPLES
  • The present invention will next be described by way of examples, which should not be construed as limiting the invention thereto.
  • Each of the skin-revitalizing agents shown in Table 1 was incorporated into purified water in an amount (wt. %) shown therein. In the Comparative Examples, each of the skin-revitalizing agents shown in Table 1 was added to purified water in an amount shown therein, followed by stirring at 50° C. for 30 minutes and then cooling to 20° C. Immediately thereafter, the state of dissolution was observed (shown in the column “Immediately after dissolution” of Table 1). Subsequently, the sample was stored at 5° C. for 24 hours, and the state of dissolution was also observed (shown in the column “After storage” of Table 1).
  • In the Examples, each of the skin-revitalizing agents shown in Table 1 was added to purified water in an amount shown therein, followed by stirring at 50° C. for 30 minutes. The resultant aqueous dispersion was subjected to a nanoparticle-forming treatment by means of Nanomaker (product of Nanomax). The thus-formed nanoparticles of the skin-revitalizing agent were found to have a size of 80 nm. Thereafter, the thus-treated dispersion was cooled to 20° C. Immediately thereafter, the state of dissolution was observed (shown in the column “Immediately after dissolution” of Table 1). Subsequently, the sample was stored at 5° C. for 24 hours, and the state of dissolution was also observed (shown in the column “After storage” of Table 1).
  • TABLE 1 Skin- Comparative Examples Examples revitalizing Immediately Immediately agent Amount after dissolution After storage after dissolution After storage Aloe extract   1% Dissolved Dissolved Dissolved Dissolved   5% Dissolved Dissolved Dissolved Dissolved  10% Dissolved Precipitation Dissolved Dissolved of crystals  15% Not dissolved Precipitation Dissolved Dissolved of crystals Placenta   1% Dissolved Dissolved Dissolved Dissolved extract   5% Dissolved Precipitation Dissolved Dissolved of crystals  10% Dissolved Precipitation Dissolved Dissolved of crystals  15% Not dissolved Precipitation Dissolved Dissolved of crystals Hydrolyzed   1% Dissolved Dissolved Dissolved Dissolved elastin   5% Dissolved Dissolved Dissolved Dissolved  10% Dissolved Precipitation Dissolved Dissolved of crystals  15% Dissolved Precipitation Dissolved Dissolved of crystals Hydrolyzed   1% Dissolved Dissolved Dissolved Dissolved collagen   5% Dissolved Dissolved Dissolved Dissolved  10% Dissolved Dissolved Dissolved Dissolved  15% Dissolved Precipitation Dissolved Dissolved of crystals Sodium 0.5% Dissolved Dissolved Dissolved Dissolved hyaluronate   1% Dissolved Dissolved Dissolved Dissolved   2% Not dissolved Not dissolved Dissolved Dissolved
  • As is clear from the data shown in Table 1, the cosmetic compositions of the present invention, which contain nanoparticles of a skin-revitalizing agent, maintained a dissolved state even when they had high skin-revitalizing agent concentrations.
  • As described above, the cosmetic composition of the present invention is suitable for use as a skin-revitalizer for alleviating or eliminating skin problems such as dry skin, wrinkles, and age spots.

Claims (2)

1. A skin-revitalizing cosmetic composition containing a skin-revitalizing agent selected from the group consisting of aloe extract, placenta extract, hydrolyzed elastin, hydrolyzed collagen, and sodium hyaluronate, wherein the skin-revitalizing agent is in the form of nanoparticles obtained through a nanoparticle-forming treatment.
2. A skin-revitalizing cosmetic composition as described in claim 1, which contains the skin-revitalizing agent at a concentration of more than 1 wt. % and up to 10 wt. %.
US12/051,987 2007-10-10 2008-03-20 Skin-revitalizing cosmetic composition Abandoned US20090098214A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2007263907A JP2009091298A (en) 2007-10-10 2007-10-10 Skin-revitalizing cosmetic
JP2007-263907 2007-10-10

Publications (1)

Publication Number Publication Date
US20090098214A1 true US20090098214A1 (en) 2009-04-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
US12/051,987 Abandoned US20090098214A1 (en) 2007-10-10 2008-03-20 Skin-revitalizing cosmetic composition

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US (1) US20090098214A1 (en)
JP (1) JP2009091298A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9132156B1 (en) 2014-06-15 2015-09-15 Amnio Technology Llc Acellular amnion derived therapeutic compositions
US10253090B2 (en) 2016-03-22 2019-04-09 Avicenna Nutraceutical, Llc Hydrolyzed collagen compositions and methods of making thereof
US10363278B2 (en) 2014-06-15 2019-07-30 Amnio Technology Llc Frozen therapeutic dose and package

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2415891A4 (en) 2009-04-03 2014-11-19 Kobe Steel Ltd Cold-rolled steel sheet and process for producing same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080254126A1 (en) * 2006-04-07 2008-10-16 Shinji Shimada Composition comprising nanoparticle ginkgo biloba extract with the effect of brain function activation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0753647B2 (en) * 1986-05-21 1995-06-07 ライオン株式会社 Liquid transparent skin cosmetics
JPH0253708A (en) * 1988-08-17 1990-02-22 Hiroshi Nishida Preparation of peelable pack for smoothening wrinkle
JP2642486B2 (en) * 1989-08-04 1997-08-20 田辺製薬株式会社 Ultra-fine particles Act of poorly soluble drugs
DE10010113B4 (en) * 2000-03-03 2009-05-07 Wolfgang Dr. Schatton Native sponge collagen, process for its isolation and its use, as well as native nanoparticulate sponge collagen, process for its preparation and its use
JP2003238380A (en) * 2002-02-12 2003-08-27 Cosmos Technical Center:Kk Cosmetic
JP2003300854A (en) * 2002-04-05 2003-10-21 Seiwa Kasei:Kk Skin cosmetic
JP2005206567A (en) * 2004-01-26 2005-08-04 Iwamoto Shigemi Healthy collagen cosmetic
JP2005320260A (en) * 2004-05-06 2005-11-17 Greatforce Biochem Tech Co Ltd Conjugated nano-collagen protein
JP2007063230A (en) * 2005-09-02 2007-03-15 Ono Pharmaceut Co Ltd Composite particle containing hardly absorbable drug
JP5112669B2 (en) * 2005-09-30 2013-01-09 富山化学工業株式会社 Aqueous suspension containing nanoparticle of poorly soluble drug
JP2007176869A (en) * 2005-12-28 2007-07-12 Ono Pharmaceut Co Ltd Slightly soluble medicament-containing fine particle

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080254126A1 (en) * 2006-04-07 2008-10-16 Shinji Shimada Composition comprising nanoparticle ginkgo biloba extract with the effect of brain function activation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9132156B1 (en) 2014-06-15 2015-09-15 Amnio Technology Llc Acellular amnion derived therapeutic compositions
US10363278B2 (en) 2014-06-15 2019-07-30 Amnio Technology Llc Frozen therapeutic dose and package
US10253090B2 (en) 2016-03-22 2019-04-09 Avicenna Nutraceutical, Llc Hydrolyzed collagen compositions and methods of making thereof

Also Published As

Publication number Publication date
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Legal Events

Date Code Title Description
AS Assignment

Owner name: ASKA CORPORATION CO., LTD., JAPAN

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:NANBU, TERUYUKI;REEL/FRAME:020680/0135

Effective date: 20080111

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION