US20080228205A1 - Ventricular partitioning device - Google Patents

Ventricular partitioning device Download PDF

Info

Publication number
US20080228205A1
US20080228205A1 US12125015 US12501508A US2008228205A1 US 20080228205 A1 US20080228205 A1 US 20080228205A1 US 12125015 US12125015 US 12125015 US 12501508 A US12501508 A US 12501508A US 2008228205 A1 US2008228205 A1 US 2008228205A1
Authority
US
Grant status
Application
Patent type
Prior art keywords
device
patient
heart
membrane
reinforced membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12125015
Inventor
Hugh R. Sharkey
Alexander Khairkhahan
Serjan D. Nikolic
Branislav Radovancevic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Edwards Lifesciences Corp
Original Assignee
CardioKinetix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12122Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder within the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12136Balloons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12168Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure
    • A61B17/12172Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device having a mesh structure having a pre-set deployed three-dimensional shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12181Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
    • A61B17/12186Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices liquid materials adapted to be injected
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12095Threaded connection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • A61F2/2478Passive devices for improving the function of the heart muscle, i.e. devices for reshaping the external surface of the heart, e.g. bags, strips or bands
    • A61F2/2487Devices within the heart chamber, e.g. splints

Abstract

This invention is directed to a partitioning device for separating a patient's heart chamber into a productive portion and a non-productive portion. The device is particularly suitable for treating patients with congestive heart failure. The partitioning device has a reinforced, expandable membrane which separates the productive and non-productive portions of the heart chamber and a support or spacing member extending between the reinforced membrane and the wall of the patient's heart chamber. The support or spacing member has a non-traumatic distal end to engage the ventricular wall.

Description

    CROSS REFERENCE TO RELATED APPLICATIONS
  • This is a divisional of pending U.S. patent application Ser. No. 10/754,182, filed on Jan. 9, 2004, which application is incorporated by reference as if fully set forth herein.
  • INCORPORATION BY REFERENCE
  • All publications and patent applications mentioned in this specification are herein incorporated by reference to the same extent as if each individual publication or patent application was specifically and individually indicated to be incorporated by reference.
  • FIELD OF THE INVENTION
  • The present invention relates generally to the field of treating congestive heart failure and more specifically, to a device and method for partitioning a patient's heart chamber and a system for delivering the treatment device.
  • BACKGROUND OF THE INVENTION
  • Congestive heart failure (CHF) is characterized by a progressive enlargement of the heart, particularly the left ventricle and is a major cause of death and disability in the United States. Approximately 500,000 cases occur annually in the U.S. alone. As the patient's heart enlarges, it cannot efficiently pump blood forward with each heart beat. In time, the heart becomes so enlarged the heart cannot adequately supply blood to the body. Even in healthy hearts only a certain percentage of the blood in a patient's left ventricle is pumped out or ejected from the chamber during each stroke of the heart. The pumped percentage, commonly referred to as the “ejection fraction”, is typically about sixty percent for a healthy heart. A patient with congestive heart failure can have an ejection fraction of less than 40% and sometimes lower. As a result of the low ejection fraction, a patient with congestive heart failure is fatigued, unable to perform even simple tasks requiring exertion and experiences pain and discomfort. Further, as the heart enlarges, the internal heart valves such as the mitral valve, cannot adequately close. An incompetent mitral valve allows regurgitation of blood from the left ventricle back into the left atrium, further reducing the heart's ability to pump blood forewardly.
  • Congestive heart failure can result from a variety of conditions, including viral infections, incompetent heart valves (e.g. mitral valve), ischemic conditions in the heart wall or a combination of these conditions. Prolonged ischemia and occlusion of coronary arteries can result in myocardial tissue in the ventricular wall dying and becoming scar tissue. Once the myocardial tissue dies, it is less contractile (sometimes non-contractile) and no longer contributes to the pumping action of the heart. It is referred to as hypokinetic. As the disease progresses, a local area of compromised myocardium may bulge out during the heart contractions, further decreasing the heart's ability to pump blood and further reducing the ejection fraction. In this instance, the heart wall is referred to as dyskinetic or akinetic. The dyskinetic region of the heart wall may stretch and eventually form an aneurysmic bulge.
  • Patients suffering from congestive heart failure are commonly grouped into four classes, Classes I, II, III and IV. In the early stages, Classes I and II, drug therapy is presently the most commonly prescribed treatment. Drug therapy typically treats the symptoms of the disease and may slow the progression of the disease, but it can not cure the disease. Presently, the only permanent treatment for congestive heart disease is heart transplantation, but heart transplant procedures are very risky, extremely invasive and expensive and are performed on a small percentage of patients. Many patient's do not qualify for heart transplant for failure to meet any one of a number of qualifying criteria, and, Furthermore, there are not enough hearts available for transplant to meet the needs of CHF patients who do qualify.
  • Substantial effort has been made to find alternative treatments for congestive heart disease. For example, surgical procedures have been developed to dissect and remove weakened portions of the ventricular wall in order to reduce heart volume. This procedure is highly invasive, risky and expensive and is commonly only done in conjunction with other procedures (such as heart valve replacement or coronary artery by-pass graft). Additionally, the surgical treatment is usually limited to Class IV patients and, accordingly, is not an option for patients facing ineffective drug treatment prior to Class IV. Finally, if the procedure fails, emergency heart transplant is the only presently available option.
  • Other efforts to treat CHF include the use of an elastic support, such as an artificial elastic sock placed around the heart to prevent further deleterious remodeling.
  • Additionally, mechanical assist devices have been developed as intermediate procedures for treating congestive heart disease. Such devices include left ventricular assist devices and total artificial hearts. A left ventricular assist device includes a mechanical pump for increasing blood flow from the left ventricle into the aorta. Total artificial heart devices, such as the Jarvik heart, are usually used only as temporary measures while a patient awaits a donor heart for transplant.
  • Recently, improvements have been made in treating patient's with CHF by implanting pacing leads in both sides of the heart in order to coordinate the contraction of both ventricles of the heart. This technique has been shown to improve hemodynamic performance and can result in increased ejection fraction from the right ventricle to the patient's lungs and the ejection fraction from the left ventricle to the patient's aorta. While this procedure has been found to be successful in providing some relief from CHF symptoms and slowed the progression of the disease, it has not been able to stop the disease.
  • SUMMARY OF THE INVENTION
  • The present invention is directed to a ventricular partitioning device and method of employing the device in the treatment of a patient with congestive heart failure. Specifically, the ventricular chamber of the CHF patient is partitioned by the device so as to reduce its total volume and to reduce the stress applied to the heart and, as a result, improve the ejection fraction thereof.
  • A ventricular partitioning device embodying features of the invention has a reinforced membrane component, preferably self expanding, which is configured to partition the patient's ventricular heart chamber into a main productive portion and a secondary non-productive portion, and a support or spacing component extending from the distal side of the reinforced membrane for non-traumatically engaging a region of the patient's ventricular wall defining in part the secondary non-productive portion to space a central portion of the reinforced membrane from the heart wall. The partitioning device preferably includes a centrally located hub secured to the reinforced membrane. The partitioning membrane of the device may be reinforced by a radially expandable frame component formed of a plurality of ribs.
  • The ribs of the expandable frame have distal ends secured to the central hub, preferably secured to facilitate abduction of the free proximal ends of the ribs away from a centerline axis. The distal ends of the ribs may be pivotally mounted or formed of material such as superelastic NiTi alloy which allow for compressing the ribs into a contracted configuration and when released allow for their self expansion. The ribs also have free proximal ends configured to engage and preferably penetrate the tissue of the heart wall so as to secure the peripheral edge of the membrane to the heart wall and fix the position of the membrane with respect thereto. The free proximal ends of the ribs may have tissue penetrating tips such as barbs or hooks. The partitioning membrane is secured to the ribs of the expandable frame, preferably on the proximal or pressure side of the expandable frame.
  • The supporting component or stem of the device has a length configured to extend to the heart wall (typically about 5 mm to about 50 mm, preferably about 15 to about 35 mm), to support and space the membrane from the heart wall. While only one supporting component or stem is described herein, a plurality of such components may be utilized. The supporting component or stem may have at least one inner lumen extending therein for delivery of therapeutic or diagnostic agents through the ports provided along the length thereof. The stem is provided with one or more flexible bumper-type elements on its distal end to non-traumatically engage the weakened ventricular wall and maintain the reinforced membrane, preferably the central portion thereof, spaced a desired distance from the weakened ventricular wall.
  • The partitioning membrane in the expanded configuration has radial dimensions from about 10 to about 160 mm, preferably about 50 to about 100 mm, as measured from the center line axis.
  • The partitioning device may be delivered percutaneously or intraoperatively. It is relatively easy to install and provides substantial improvement in the ejection fraction of the patient's heart chamber. These and other advantages of the invention will become more apparent from the following detailed description of the invention and the accompanying exemplary drawings.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is a schematic perspective view of a ventricular partitioning device embodying features of the invention.
  • FIG. 2 is an elevational view of a delivery system for the partitioning device shown in FIG. 1
  • FIG. 3 is an enlarged view of the encircled region 3-3 shown in FIG. 2.
  • FIG. 4 is a simplified view with parts removed similar to that shown in FIG. 3 with the delivery catheter connected to the partitioning device.
  • FIG. 5 is an end view of the hub which is secured in the proximal end of the stem of the partitioning device shown in FIG. 1.
  • FIG. 6 is a schematic view of a patient's left ventricular chamber illustrating the partitioning device shown in FIG. 1 disposed within the chamber separating a working portion of the chamber from a non-working portion of the chamber.
  • FIG. 7 is a schematic perspective view of an alternative design embodying features of the invention with a pair of bumper elements on the distal end of the stem of the partitioning device.
  • FIG. 8 is a schematic perspective view of another alternative design embodying features of the invention with three bumper elements on the distal end of the stem of the partitioning device.
  • FIG. 9 is a schematic perspective view of another alternative design embodying features of the invention with four bumper elements on the distal end of the stem of the partitioning device.
  • FIG. 10 is a schematic perspective view of a fourth alternative design embodying features of the invention with a plurality of bumper elements on the distal end of the stem of the device provided with hooks which fix the end to the interior surface of the patient's ventricular wall.
  • FIG. 11 is a schematic perspective view of another alternative design embodying features of the invention with a membrane underlying a plurality of bumper elements on the distal end of the stem of the partitioning device.
  • FIG. 12 is a schematic perspective view of another alternative design embodying features of the invention with a helical coil bumper element on the distal end of the stem of the partitioning device.
  • FIG. 13 is a schematic perspective view of yet another alternative design embodying features of the invention with an inflatable balloon secured to the underside of the partitioning device to space and support the partitioning device from the heart wall.
  • DETAILED DESCRIPTION OF THE INVENTION
  • FIGS. 1-5 illustrate a partitioning device 10 which embodies features of the invention and which includes a partitioning membrane 11, a stem 12 and a radially expandable reinforcing frame 13 formed of a plurality of ribs 14. Preferably the membrane 11 is secured to the proximal or pressure side of the frame 13 as shown in FIG. 1. The distal ends 15 of the ribs 14 are secured to the central hub 16 and the proximal ends 17 of the ribs 14 are unsecured and are configured to radially extend away from a center line axis 18 which extends through the hub 16. Radial expansion of the free proximal ends 17 unfurls the membrane 11 secured to the frame 13 so that the membrane presents a relatively smooth pressure side surface. Stem 12 extends distally from the hub 16 and has a distal end 19 which has a flexible, J-shape bumper element 20 to provide a yielding engagement with a heart wall when deployed within a patient's heart chamber. The frame 13 and attached membrane 11 are collapsible toward the centerline axis 18 for delivery through a catheter.
  • The proximal or free ends 17 of ribs 14 are provided with sharp tip elements 21 which are configured to hold the frame 13 and the membrane 11 secured thereto in a deployed position within the patient's heart chamber. Preferably, the sharp tip elements 21 of the frame 13 penetrate into tissue of the patient's heart wall in order to secure the reinforced membrane 11 so as to partition the ventricular chamber in a desired manner.
  • As shown in FIG. 1, the stem 12 is provided with an inner lumen 22 for delivery of fluid to the non-operative portion of the ventricular chamber and discharge ports 23 are provided in the stem. The hub 16 is secured within the inner lumen 22 in the proximal end of stem 12 suitable means such as a friction fit, an adhesive bond or a pin. The hub 16 has a deployment pin 24, as shown in FIG. 5, which as will be described later allows the partitioning device 10 to be deployed within the patient's heart chamber and released from a delivery system used to place the device. The distal ends of the reinforcing ribs 14 are secured to the hub 16 in a suitable manner. They may be secured to the surface defining the inner lumen or the hub may be provided with channels or bores in the wall of the hub into which the distal ends of the ribs may be secured. The ribs 14 are preshaped so that when not constrained (as shown in FIGS. 1 and 2), the free proximal ends 17 thereof expand to a desired angular displacement (.theta.) away from a center line axis 18 which is about 20.degree. to about 90.degree., preferably about 50.degree. to about 80.degree.
  • FIGS. 2-4 illustrate a suitable delivery system 30 with a partitioning component device 10 as shown in FIG. 1. The delivery system 30 includes a control handle 31 with a delivery catheter 32 having a deploying coil screw 33 secured to the distal end 34 for releasing the partitioning device 10 from the delivery system 30. The delivery catheter 32 has an inner lumen 35 through which therapeutic or diagnostic fluids may be delivered. The delivery catheter 32 extends through the handle 31 and the proximal end of the catheter 32 is secured to torquing knob 36 to allow rotation of the catheter by rotating knob 36. An injection port 37 is provided in fluid communication with the delivery catheter 32 for injecting therapeutic or diagnostic fluids through the inner lumen 35.
  • The delivery system 30 may be introduced into a patient's body through guiding catheter or cannula 40 which has an inner lumen 41. A radiopaque marker (not shown) may be provided on the distal end of the guiding catheter 40 to aid in fluoroscopically guiding the catheter to the desired location. The partitioning device 10 is slidably disposed within the inner lumen 41 with the free proximal ends 17 of the ribs 14 in a constricted configuration. The guiding catheter 40 is percutaneously introduced in a conventional fashion into the patient's vasculature and advanced therein until the distal end 42 of the guiding catheter 40 is position close to the desired location for the partitioning device 10 within the patient's heart chamber such as the left ventricle. The delivery system 30 is advanced distally within the inner lumen 41 until the J-shaped bumper 20 extends out the distal end 42 of the guiding catheter 40 and engages the ventricular wall. With the delivery system 30 held in place and the bumper 20 engaging the ventricular wall, the guide catheter 40 is pulled proximally until the free ends 17 of ribs 14 are released from the distal end 42 so that anchoring tip elements 21 on the free proximal ends 17 of ribs 14 penetrate into tissue of the patient's heart wall as shown in FIG. 6 to secure the partitioning device 10 within the patient's heart chamber. With the partitioning device 10 properly positioned within the heart chamber, the delivery catheter 32 is rotated counter-clockwise to disengage the delivery system 30 from the hub 16. Upon the counter-clockwise rotation of the delivery catheter 32, the helical coil screw 33 attached to the distal end 34 of the delivery catheter 32 rides on the deployment pin 24 secured within the inner lumen 22 of the hub 16. The delivery system 30 and the guide catheter 40 may then be removed from the patient. The proximal end of the guide catheter 40 is provided with an injection port 43 to inject therapeutic or diagnostic fluids through the inner lumen 41.
  • FIG. 6 illustrates the placement of partitioning device 10 within a patient's left ventricle 45. The membrane 11 secured to the proximal side of ribs 14 partitions the patient's heart chamber 45 into a main productive or operational portion 46 and a secondary, essentially non-productive portion 47. The operational portion 46 is much smaller than the original ventricular chamber 45 and provides for an improved ejection fraction. The partitioning increases the ejection fraction and provides an improvement in blood flow. Over time, the non-productive portion 47 fills initially with thrombus and subsequently cellular growth. Bio-resorbable fillers such as polylactic acid, polyglycolic acid, polycaprolactone and copolymers and blends may be employed to fill the non-productive portion 47. Fillers may be suitably supplied in a suitable solvent such as DMSO. Other materials which accelerate tissue growth may be deployed in the non-productive portion 47.
  • FIGS. 7-12 illustrate distal ends 19 of the partitioning devices having alternative bumper elements for providing non-traumatic contact with a weakened ventricular wall. In FIG. 7 the distal end 19 of stem 12 has a pair of J-shaped bumpers 50 and 51. In FIG. 8 the distal end 19 has three J-shaped bumpers 52, 53 and 54. FIG. 9 illustrates a distal end 19 having three J-shaped bumpers 55, 56, 57 and 58. FIG. 10 depicts a slight change, where the distal end 19 has four wire J-shaped bumpers 59-62 (not shown in drawing) with sharp tips 63-66 (not shown) for securing the ends of the bumpers in heart tissue. A further alternative is illustrated in FIG. 11 where a membrane 68 is applied to the J-shaped bumpers In FIG. 12, the distal end 19 of stem 12 is provided with a coiled bumper 70 for engaging a ventricular wall.
  • Another modification is shown in FIG. 13 wherein an inflatable balloon 80 is provided on the distal side of the frame 13 to support and space the partitioning device 10 from a patient's ventricular wall in lieu of the stem with flexible bumpers, as shown in the partitioning devices previously described.
  • The ribs 14 of the partitioning device have a length of about 1 to about 8 cm, preferably, about 1.5 to about 4 cm for most left ventricle deployments. To assist in properly locating the device during advancement and placement thereof into a patient's heart chamber, the distal extremity of one or more of the ribs and/or the stem may be provided with markers at desirable locations that provide enhanced visualization by eye, by ultrasound, by X-ray, or other imaging or visualization means. Radiopaque markers may be made with, for example, stainless steel, platinum, gold, iridium, tantalum, tungsten, silver, rhodium, nickel, bismuth, other radiopaque metals, alloys and oxides of these metals.
  • The membrane 11 may be formed of suitable biocompatitble polymeric material which include ePTFE (expanded polytetrafluoroethylene), Nylon, PET (polyethylene terephthalate) and polyesters such as Hytrel. The membrane 11 is preferably foraminous in nature to facilitate tissue ingrowth after deployment within the patient's heart. The delivery catheter and the guiding catheter may be formed of suitable high strength polymeric material such as PEEK (polyetheretherketone), polycarbonate, PET, Nylon, and the like. Braided composite shafts may also be employed. To the extent not otherwise described herein, the various components of the partitioning device and delivery system may be formed of conventional materials and in a conventional manner as will be appreciated by those skilled in the art.
  • While particular forms of the invention have been illustrated and described herein, it will be apparent that various modifications and improvements can be made to the invention. Moreover, individual features of embodiments of the invention may be shown in some drawings and not in others, but those skilled in the art will recognize that individual features of one embodiment of the invention can be combined with any or all the features of another embodiment. Accordingly, it is not intended that the invention be limited to the specific embodiments illustrated. It is intended that this invention to be defined by the scope of the appended claims as broadly as the prior art will permit.
  • Terms such a “element”, “member”, “device”, “section”, “portion”, “steps”, “means” and words of similar import when used herein shall not be construed as invoking the provisions of 35 U.S.C. .sctn.112(6) unless the following claims expressly use the terms “means” followed by a particular function without specific structure or “step” followed by a particular function without specific action. All patents and patent applications referred to above are hereby incorporated by reference in their entirety. Accordingly, it is not intended that the invention be limited, except as by the appended claims.

Claims (35)

  1. 1. A device for increasing the ejection fraction of a patient's heart chamber, comprising:
    a. a reinforced membrane component which has a proximal face and a distal face and which is configured to partition the patient's heart chamber into a main operational portion and a secondary, non-operational portion; and
    b. a support component which is disposed in the non-productive portion of the heart chamber defined in part by the distal face of the reinforced membrane and which is configured to extend from the reinforced membrane to a region of the heart wall defining in part the heart chamber.
  2. 2. The device of claim 1 wherein reinforced membrane has a contracted configuration about a center line axis and an expanded configuration in which the membrane periphery is radially expanded away from the center line axis.
  3. 3. The device of claim 1 wherein the support component is at least in part an elongated stem.
  4. 4. The device of claim 1 wherein the support component has a distal extremity which is configured to non-traumatically engage a region of the patient's ventricular wall defining in part the secondary non-operational portion of the heart chamber.
  5. 5. The device of claim 4 wherein the distal extremity of the support component has at least one J-shaped bumper element.
  6. 6. The device of claim 4 wherein the distal extremity has from two to four J-shaped elements.
  7. 7. The device of claim 4 wherein the distal extremity has a coil shaped element.
  8. 8. The device of claim 1 including a hub secured to a central location of the reinforced membrane.
  9. 9. The device of claim 8 wherein the membrane is reinforced by a frame which is radially expandable at a proximal extremity thereof.
  10. 10. The device of claim 9 wherein the radially expandable frame has a plurality of ribs.
  11. 11. The device of claim 10 wherein the ribs have distal ends secured to the central hub.
  12. 12. The device of claim 11 wherein the distal ends of the ribs are secured to the central hub to facilitate abduction of the free proximal ends away from a centerline axis to facilitate expansion of the reinforced membrane component.
  13. 13. The device of claim 12 wherein the ribs have free proximal ends configured to engage the heart wall and secure the device within the heart chamber.
  14. 14. The device of claim 13 wherein the free proximal ends of the ribs have tissue penetrating tips.
  15. 15. The device of claim 9 wherein the membrane is secured to the ribs on a proximal side of the expandable frame.
  16. 16. The device of claim 9 wherein the reinforced membrane component restricts the radial expansion of the free proximal ends of the ribs to an angle of about 60° to about 90° from a center line axis.
  17. 17. The device of claim 16 wherein the radial expansion of the free proximal ends of the ribs are about 30° to about 60°.
  18. 18. The device of claim 3 wherein the stem is configured to extend to the ventricular wall.
  19. 19. The device of claim 1 wherein the support component is at least in part an inflatable member.
  20. 20. The device of claim 1 wherein the membrane has radial dimensions from a center line axis of about 10 to about 160 mm.
  21. 21. The device of claim 1 wherein the member has radial dimensions from a center line axis of about 5 to about 80 mm.
  22. 22. The device of claim 9 wherein the frame has about 3 to about 30 ribs.
  23. 23. The device of claim 9 wherein the frame has about 6 to about 16 ribs.
  24. 24. The device of claim 9 wherein the expandable frame is self expanding.
  25. 25. The device of claim 9 wherein the frame is formed of superelastic NiTi alloy which is in an austenite phase when unstressed.
  26. 26. The device of claim 9 wherein the frame is in a stress maintained martensite phase when delivered through the patient's vasculature to the patient's heart chamber.
  27. 27. The device of claim 1 wherein the membrane is formed at least in part of expanded fluoropolymer.
  28. 28. The device of claim 27 wherein the expanded fluoropolymer is polytetrafluoroethylene.
  29. 29. The device of claim 1 wherein the membrane is at least in part formed of a foraminous sheet.
  30. 30. A method of treating a patient with congestive heart failure, comprising:
    a. providing a reinforced membrane;
    b. positioning the reinforced membrane within a chamber of the patient's heart with a peripheral edge of the reinforced membrane being secured to a wall defining at least in part the patient's heart chamber; and
    c. spacing a central portion of the reinforced membrane from the heart wall.
  31. 31. The method of claim 30 wherein the reinforced membrane is delivered in a folded configuration and expanded in position within the patient's heart wall.
  32. 32. The method of claim 31 wherein the reinforced membrane is first positioned within an inner lumen of an elongated catheter and the catheter is percutaneously introduced into the patient's vasculature and advanced therein to the patient's heart chamber wherein the reinforced membrane is discharged from the catheter.
  33. 33. The method of claim 31 wherein the edge of the reinforced membrane is secured to the heart wall defining at least in part the heart chamber by anchoring elements provided on the edge of the reinforced membrane.
  34. 34. The method of claim 30 wherein the reinforced membrane is self expanding.
  35. 35. A method of treating a patient with congestive heart failure, comprising the steps of:
    a. providing a reinforced membrane;
    b. positioning the reinforced membrane within a chamber of the patient's heart with a peripheral edge of the reinforced membrane being secured to a wall defining at least in part the patient's heart chamber; and
    c. spacing a central portion of the reinforced membrane from the heart wall.
US12125015 2004-01-09 2008-05-21 Ventricular partitioning device Abandoned US20080228205A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10754182 US7399271B2 (en) 2004-01-09 2004-01-09 Ventricular partitioning device
US12125015 US20080228205A1 (en) 2004-01-09 2008-05-21 Ventricular partitioning device

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12125015 US20080228205A1 (en) 2004-01-09 2008-05-21 Ventricular partitioning device
US12893832 US9078660B2 (en) 2000-08-09 2010-09-29 Devices and methods for delivering an endocardial device
US14731161 US20150265405A1 (en) 2000-08-09 2015-06-04 Devices and methods for delivering an endocardial device
US15133080 US10064696B2 (en) 2000-08-09 2016-04-19 Devices and methods for delivering an endocardial device

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US10754182 Division US7399271B2 (en) 2004-01-09 2004-01-09 Ventricular partitioning device

Publications (1)

Publication Number Publication Date
US20080228205A1 true true US20080228205A1 (en) 2008-09-18

Family

ID=34739326

Family Applications (2)

Application Number Title Priority Date Filing Date
US10754182 Active 2026-02-26 US7399271B2 (en) 2004-01-09 2004-01-09 Ventricular partitioning device
US12125015 Abandoned US20080228205A1 (en) 2004-01-09 2008-05-21 Ventricular partitioning device

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US10754182 Active 2026-02-26 US7399271B2 (en) 2004-01-09 2004-01-09 Ventricular partitioning device

Country Status (5)

Country Link
US (2) US7399271B2 (en)
EP (1) EP1708642A1 (en)
JP (1) JP4519858B2 (en)
CA (1) CA2559320C (en)
WO (1) WO2005070330A1 (en)

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120095499A1 (en) * 2010-10-19 2012-04-19 Allergan, Inc. Upper stomach gastric implants
US8377114B2 (en) 1999-08-09 2013-02-19 Cardiokinetix, Inc. Sealing and filling ventricular partitioning devices to improve cardiac function
US8500790B2 (en) 1999-08-09 2013-08-06 Cardiokinetix, Inc. Retrievable cardiac devices
US8672827B2 (en) 1999-08-09 2014-03-18 Cardiokinetix, Inc. Cardiac device and methods of use thereof
US8827892B2 (en) 2002-08-01 2014-09-09 Cardiokinetix, Inc. Therapeutic methods and devices following myocardial infarction
US8834519B2 (en) 1998-11-06 2014-09-16 Artritech, Inc. Method and device for left atrial appendage occlusion
US8864840B2 (en) 2010-10-19 2014-10-21 Apollo Endosurgery, Inc. Intragastric implants with collapsible frames
US8870966B2 (en) 2010-10-18 2014-10-28 Apollo Endosurgery, Inc. Intragastric balloon for treating obesity
US8920447B2 (en) 2010-10-19 2014-12-30 Apollo Endosurgery, Inc. Articulated gastric implant clip
US8956380B2 (en) 2010-10-18 2015-02-17 Apollo Endosurgery, Inc. Reactive intragastric implant devices
US9039597B2 (en) 2009-10-26 2015-05-26 Cardiokinetix, Inc. Ventricular volume reduction
US9078660B2 (en) 2000-08-09 2015-07-14 Cardiokinetix, Inc. Devices and methods for delivering an endocardial device
CN105476733A (en) * 2016-01-27 2016-04-13 张刚成 Ventricular volume reduction means
US9332993B2 (en) 2004-08-05 2016-05-10 Cardiokinetix, Inc. Devices and methods for delivering an endocardial device
US9332992B2 (en) 2004-08-05 2016-05-10 Cardiokinetix, Inc. Method for making a laminar ventricular partitioning device
US9398969B2 (en) 2010-10-19 2016-07-26 Apollo Endosurgery, Inc. Upper stomach gastric implants
US9463107B2 (en) 2010-10-18 2016-10-11 Apollo Endosurgery, Inc. Variable size intragastric implant devices
US9498365B2 (en) 2010-10-19 2016-11-22 Apollo Endosurgery, Inc. Intragastric implants with multiple fluid chambers
CN106344081A (en) * 2016-09-28 2017-01-25 宁波迪创医疗科技有限公司 Volume reduction mechanism for left ventricle
US9668901B2 (en) 2010-10-18 2017-06-06 Apollo Endosurgery Us, Inc. Intragastric implants with duodenal anchors
US9694121B2 (en) 1999-08-09 2017-07-04 Cardiokinetix, Inc. Systems and methods for improving cardiac function
US10064696B2 (en) 2000-08-09 2018-09-04 Edwards Lifesciences Corporation Devices and methods for delivering an endocardial device
US10070980B2 (en) 2010-10-19 2018-09-11 Apollo Endosurgery Us, Inc. Anchored non-piercing duodenal sleeve and delivery systems

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7862500B2 (en) * 2002-08-01 2011-01-04 Cardiokinetix, Inc. Multiple partitioning devices for heart treatment
US8257428B2 (en) * 1999-08-09 2012-09-04 Cardiokinetix, Inc. System for improving cardiac function
US7279007B2 (en) * 1999-08-09 2007-10-09 Cardioklnetix, Inc. Method for improving cardiac function
US20030109770A1 (en) * 1999-08-09 2003-06-12 Sharkey Hugh R. Device with a porous membrane for improving cardiac function
US20060229491A1 (en) * 2002-08-01 2006-10-12 Cardiokinetix, Inc. Method for treating myocardial rupture
US7513867B2 (en) * 2003-07-16 2009-04-07 Kardium, Inc. Methods and devices for altering blood flow through the left ventricle
US7762943B2 (en) * 2004-03-03 2010-07-27 Cardiokinetix, Inc. Inflatable ventricular partitioning device
US20060030881A1 (en) 2004-08-05 2006-02-09 Cardiokinetix, Inc. Ventricular partitioning device
US7860556B2 (en) 2005-02-02 2010-12-28 Voyage Medical, Inc. Tissue imaging and extraction systems
US8137333B2 (en) * 2005-10-25 2012-03-20 Voyage Medical, Inc. Delivery of biological compounds to ischemic and/or infarcted tissue
US8221310B2 (en) 2005-10-25 2012-07-17 Voyage Medical, Inc. Tissue visualization device and method variations
US7918787B2 (en) 2005-02-02 2011-04-05 Voyage Medical, Inc. Tissue visualization and manipulation systems
US8050746B2 (en) 2005-02-02 2011-11-01 Voyage Medical, Inc. Tissue visualization device and method variations
US9055906B2 (en) 2006-06-14 2015-06-16 Intuitive Surgical Operations, Inc. In-vivo visualization systems
US7860555B2 (en) 2005-02-02 2010-12-28 Voyage Medical, Inc. Tissue visualization and manipulation system
US9510732B2 (en) 2005-10-25 2016-12-06 Intuitive Surgical Operations, Inc. Methods and apparatus for efficient purging
US10064540B2 (en) 2005-02-02 2018-09-04 Intuitive Surgical Operations, Inc. Visualization apparatus for transseptal access
US7930016B1 (en) 2005-02-02 2011-04-19 Voyage Medical, Inc. Tissue closure system
US8078266B2 (en) 2005-10-25 2011-12-13 Voyage Medical, Inc. Flow reduction hood systems
US7320665B2 (en) 2005-03-02 2008-01-22 Venkataramana Vijay Cardiac Ventricular Geometry Restoration Device and Treatment for Heart Failure
US20060199995A1 (en) * 2005-03-02 2006-09-07 Venkataramana Vijay Percutaneous cardiac ventricular geometry restoration device and treatment for heart failure
US8398537B2 (en) 2005-06-10 2013-03-19 Cardiokinetix, Inc. Peripheral seal for a ventricular partitioning device
US7582051B2 (en) * 2005-06-10 2009-09-01 Cardiokinetix, Inc. Peripheral seal for a ventricular partitioning device
WO2007130724A3 (en) * 2006-02-06 2008-01-17 Northwind Ventures Systems and methods for volume reduction
US7749249B2 (en) 2006-02-21 2010-07-06 Kardium Inc. Method and device for closing holes in tissue
US20070270688A1 (en) 2006-05-19 2007-11-22 Daniel Gelbart Automatic atherectomy system
US9119633B2 (en) 2006-06-28 2015-09-01 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US8449605B2 (en) 2006-06-28 2013-05-28 Kardium Inc. Method for anchoring a mitral valve
US8920411B2 (en) 2006-06-28 2014-12-30 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US10028783B2 (en) 2006-06-28 2018-07-24 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US7837610B2 (en) * 2006-08-02 2010-11-23 Kardium Inc. System for improving diastolic dysfunction
US10004388B2 (en) 2006-09-01 2018-06-26 Intuitive Surgical Operations, Inc. Coronary sinus cannulation
US20080097476A1 (en) 2006-09-01 2008-04-24 Voyage Medical, Inc. Precision control systems for tissue visualization and manipulation assemblies
JP2010502313A (en) 2006-09-01 2010-01-28 ボエッジ メディカル, インコーポレイテッド Method and apparatus for the treatment of atrial fibrillation
DE602007006973D1 (en) * 2006-09-29 2010-07-15 Cordis Corp Intraluminal single disk device for open foramen ovale
US8029556B2 (en) * 2006-10-04 2011-10-04 Edwards Lifesciences Corporation Method and apparatus for reshaping a ventricle
US20090315402A1 (en) * 2006-10-04 2009-12-24 The Tokyo Electric Power Company, Incorporated Ac-dc conversion device
US8131350B2 (en) 2006-12-21 2012-03-06 Voyage Medical, Inc. Stabilization of visualization catheters
US8758229B2 (en) 2006-12-21 2014-06-24 Intuitive Surgical Operations, Inc. Axial visualization systems
FR2915087A1 (en) 2007-04-20 2008-10-24 Corevalve Inc Implant treatment of a heart valve, particularly a mitral valve implant inculant material and equipment for setting up of this implant.
JP2010524651A (en) 2007-04-27 2010-07-22 ボエッジ メディカル, インコーポレイテッド Steerable tissue visualization and manipulation the catheter with a complex shape
US8657805B2 (en) 2007-05-08 2014-02-25 Intuitive Surgical Operations, Inc. Complex shape steerable tissue visualization and manipulation catheter
EP2155036B1 (en) 2007-05-11 2016-02-24 Intuitive Surgical Operations, Inc. Visual electrode ablation systems
US8308752B2 (en) * 2007-08-27 2012-11-13 Cook Medical Technologies Llc Barrel occlusion device
US20090062838A1 (en) * 2007-08-27 2009-03-05 Cook Incorporated Spider device with occlusive barrier
US8734483B2 (en) * 2007-08-27 2014-05-27 Cook Medical Technologies Llc Spider PFO closure device
US8025495B2 (en) * 2007-08-27 2011-09-27 Cook Medical Technologies Llc Apparatus and method for making a spider occlusion device
US8235985B2 (en) 2007-08-31 2012-08-07 Voyage Medical, Inc. Visualization and ablation system variations
US8906011B2 (en) 2007-11-16 2014-12-09 Kardium Inc. Medical device for use in bodily lumens, for example an atrium
US8489172B2 (en) 2008-01-25 2013-07-16 Kardium Inc. Liposuction system
US8858609B2 (en) 2008-02-07 2014-10-14 Intuitive Surgical Operations, Inc. Stent delivery under direct visualization
US20090287304A1 (en) 2008-05-13 2009-11-19 Kardium Inc. Medical Device for Constricting Tissue or a Bodily Orifice, for example a mitral valve
US9101735B2 (en) 2008-07-07 2015-08-11 Intuitive Surgical Operations, Inc. Catheter control systems
US8894643B2 (en) 2008-10-10 2014-11-25 Intuitive Surgical Operations, Inc. Integral electrode placement and connection systems
US8333012B2 (en) 2008-10-10 2012-12-18 Voyage Medical, Inc. Method of forming electrode placement and connection systems
US8500622B2 (en) * 2008-10-20 2013-08-06 Corassist Cardiovascular Ltd. Ventricular function assisting device and a method and apparatus for implanting it
US9468364B2 (en) 2008-11-14 2016-10-18 Intuitive Surgical Operations, Inc. Intravascular catheter with hood and image processing systems
US20100204561A1 (en) * 2009-02-11 2010-08-12 Voyage Medical, Inc. Imaging catheters having irrigation
WO2011011642A3 (en) * 2009-07-22 2011-06-03 The Texas A&M University System Biphasic and dynamic adjustable support devices and methods with assist and recoil capabilities for treatment of cardiac pathologies
WO2011041571A3 (en) 2009-10-01 2011-08-04 Kardium Inc. Medical device, kit and method for constricting tissue or a bodily orifice, for example, a mitral valve
US8694071B2 (en) 2010-02-12 2014-04-08 Intuitive Surgical Operations, Inc. Image stabilization techniques and methods
US9814522B2 (en) 2010-04-06 2017-11-14 Intuitive Surgical Operations, Inc. Apparatus and methods for ablation efficacy
US9050066B2 (en) 2010-06-07 2015-06-09 Kardium Inc. Closing openings in anatomical tissue
US8888675B2 (en) * 2010-08-12 2014-11-18 Abbott Cardiovascular Systems, Inc. Apparatus and methods for supporting cardiac ischemic tissue
US8940002B2 (en) 2010-09-30 2015-01-27 Kardium Inc. Tissue anchor system
KR101270235B1 (en) 2011-01-20 2013-05-31 강원대학교산학협력단 Ventricular compartment unit
US9452016B2 (en) 2011-01-21 2016-09-27 Kardium Inc. Catheter system
US9480525B2 (en) 2011-01-21 2016-11-01 Kardium, Inc. High-density electrode-based medical device system
CA2764494A1 (en) 2011-01-21 2012-07-21 Kardium Inc. Enhanced medical device for use in bodily cavities, for example an atrium
USD777926S1 (en) 2012-01-20 2017-01-31 Kardium Inc. Intra-cardiac procedure device
USD777925S1 (en) 2012-01-20 2017-01-31 Kardium Inc. Intra-cardiac procedure device
US9072511B2 (en) 2011-03-25 2015-07-07 Kardium Inc. Medical kit for constricting tissue or a bodily orifice, for example, a mitral valve
EP2775933B1 (en) * 2011-11-09 2016-12-28 Easynotes Ltd. Obstruction device
US9198592B2 (en) 2012-05-21 2015-12-01 Kardium Inc. Systems and methods for activating transducers
US9011423B2 (en) 2012-05-21 2015-04-21 Kardium, Inc. Systems and methods for selecting, activating, or selecting and activating transducers
CN104720861B (en) * 2015-03-03 2017-09-22 上海形状记忆合金材料有限公司 Weave volume reduction means
WO2016154633A1 (en) * 2015-03-26 2016-09-29 Boston Scientific Scimed, Inc. Systems and methods for vascular occlusion

Citations (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3874388A (en) * 1973-02-12 1975-04-01 Ochsner Med Found Alton Shunt defect closure system
US4007743A (en) * 1975-10-20 1977-02-15 American Hospital Supply Corporation Opening mechanism for umbrella-like intravascular shunt defect closure device
US4425908A (en) * 1981-10-22 1984-01-17 Beth Israel Hospital Blood clot filter
US4453545A (en) * 1981-05-07 1984-06-12 Hiroshi Inoue Endotracheal tube with movable endobronchial blocker for one-lung anesthesia
US4588404A (en) * 1979-01-22 1986-05-13 Didier Lapeyre Total cardiac prosthesis
US4832055A (en) * 1988-07-08 1989-05-23 Palestrant Aubrey M Mechanically locking blood clot filter
US4917089A (en) * 1988-08-29 1990-04-17 Sideris Eleftherios B Buttoned device for the transvenous occlusion of intracardiac defects
US4983165A (en) * 1990-01-23 1991-01-08 Loiterman David A Guidance system for vascular catheter or the like
US5104399A (en) * 1986-12-10 1992-04-14 Endovascular Technologies, Inc. Artificial graft and implantation method
US5192314A (en) * 1991-12-12 1993-03-09 Daskalakis Michael K Synthetic intraventricular implants and method of inserting
US5385156A (en) * 1993-08-27 1995-01-31 Rose Health Care Systems Diagnostic and treatment method for cardiac rupture and apparatus for performing the same
US5389087A (en) * 1991-09-19 1995-02-14 Baxter International Inc. Fully exchangeable over-the-wire catheter with rip seam and gated side port
US5425744A (en) * 1991-11-05 1995-06-20 C. R. Bard, Inc. Occluder for repair of cardiac and vascular defects
US5433727A (en) * 1994-08-16 1995-07-18 Sideris; Eleftherios B. Centering buttoned device for the occlusion of large defects for occluding
US5496277A (en) * 1990-04-12 1996-03-05 Schneider (Usa) Inc. Radially expandable body implantable device
US5527337A (en) * 1987-06-25 1996-06-18 Duke University Bioabsorbable stent and method of making the same
US5527338A (en) * 1992-09-02 1996-06-18 Board Of Regents, The University Of Texas System Intravascular device
US5634936A (en) * 1995-02-06 1997-06-03 Scimed Life Systems, Inc. Device for closing a septal defect
US5634942A (en) * 1994-04-21 1997-06-03 B. Braun Celsa Assembly comprising a blood filter for temporary or definitive use and a device for implanting it
US5647870A (en) * 1993-03-16 1997-07-15 Ep Technologies, Inc. Multiple electrode support structures
US5709707A (en) * 1995-10-30 1998-01-20 Children's Medical Center Corporation Self-centering umbrella-type septal closure device
US5860951A (en) * 1992-01-07 1999-01-19 Arthrocare Corporation Systems and methods for electrosurgical myocardial revascularization
US5865730A (en) * 1997-10-07 1999-02-02 Ethicon Endo-Surgery, Inc. Tissue stabilization device for use during surgery having remotely actuated feet
US5867003A (en) * 1995-02-20 1999-02-02 Fujitsu Limited Library apparatus
US5865791A (en) * 1995-06-07 1999-02-02 E.P. Technologies Inc. Atrial appendage stasis reduction procedure and devices
US5871017A (en) * 1996-10-15 1999-02-16 Mayer; Paul W. Relative motion cancelling platform for surgery
US5876325A (en) * 1993-11-02 1999-03-02 Olympus Optical Co., Ltd. Surgical manipulation system
US5876449A (en) * 1995-04-01 1999-03-02 Variomed Ag Stent for the transluminal implantation in hollow organs
US5875782A (en) * 1996-11-14 1999-03-02 Cardiothoracic Systems, Inc. Methods and devices for minimally invasive coronary artery revascularization on a beating heart without cardiopulmonary bypass
US5879366A (en) * 1996-12-20 1999-03-09 W.L. Gore & Associates, Inc. Self-expanding defect closure device and method of making and using
US5882340A (en) * 1992-04-15 1999-03-16 Yoon; Inbae Penetrating instrument having an expandable anchoring portion for triggering protrusion of a safety member and/or retraction of a penetrating member
US5910150A (en) * 1996-12-02 1999-06-08 Angiotrax, Inc. Apparatus for performing surgery
US5916145A (en) * 1998-08-07 1999-06-29 Scimed Life Systems, Inc. Device and method of using a surgical assembly with mesh sheath
US5925076A (en) * 1995-05-19 1999-07-20 Inoue; Kanji Appliance to be implanted, method of collapsing the appliance to be implanted and method of using the appliance to be implanted
US5924424A (en) * 1993-02-22 1999-07-20 Heartport, Inc. Method and apparatus for thoracoscopic intracardiac procedures
US5928260A (en) * 1997-07-10 1999-07-27 Scimed Life Systems, Inc. Removable occlusion system for aneurysm neck
US6024096A (en) * 1998-05-01 2000-02-15 Correstore Inc Anterior segment ventricular restoration apparatus and method
US6024756A (en) * 1996-03-22 2000-02-15 Scimed Life Systems, Inc. Method of reversibly closing a septal defect
US6036720A (en) * 1997-12-15 2000-03-14 Target Therapeutics, Inc. Sheet metal aneurysm neck bridge
US6045497A (en) * 1997-01-02 2000-04-04 Myocor, Inc. Heart wall tension reduction apparatus and method
US6059715A (en) * 1997-01-02 2000-05-09 Myocor, Inc. Heart wall tension reduction apparatus
US6076013A (en) * 1999-01-14 2000-06-13 Brennan; Edward F. Apparatus and methods for treating congestive heart failure
US6077218A (en) * 1996-10-02 2000-06-20 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US6077214A (en) * 1998-07-29 2000-06-20 Myocor, Inc. Stress reduction apparatus and method
US6193731B1 (en) * 1998-10-27 2001-02-27 Fziomed, Inc. Laparoscopic insertion and deployment device
US6221092B1 (en) * 1998-03-30 2001-04-24 Nissho Corporation Closure device for transcatheter operations and catheter assembly therefor
US6231561B1 (en) * 1999-09-20 2001-05-15 Appriva Medical, Inc. Method and apparatus for closing a body lumen
US6334864B1 (en) * 2000-05-17 2002-01-01 Aga Medical Corp. Alignment member for delivering a non-symmetric device with a predefined orientation
US6343605B1 (en) * 2000-08-08 2002-02-05 Scimed Life Systems, Inc. Percutaneous transluminal myocardial implantation device and method
US20020019580A1 (en) * 2000-03-10 2002-02-14 Lilip Lau Expandable cardiac harness for treating congestive heart failure
US6348068B1 (en) * 1999-07-23 2002-02-19 Sulzer Carbomedics Inc. Multi-filament valve stent for a cardisc valvular prosthesis
US20020026092A1 (en) * 1998-05-01 2002-02-28 Buckberg Gerald D. Ventricular restoration patch
US6355052B1 (en) * 1996-02-09 2002-03-12 Pfm Produkte Fur Die Medizin Aktiengesellschaft Device for closure of body defect openings
US20020032481A1 (en) * 2000-09-12 2002-03-14 Shlomo Gabbay Heart valve prosthesis and sutureless implantation of a heart valve prosthesis
US6360749B1 (en) * 1998-10-09 2002-03-26 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence heart function
US6364896B1 (en) * 1998-11-24 2002-04-02 Embol-X, Inc. Compliant framework and methods of use
US20020055767A1 (en) * 2000-10-18 2002-05-09 Forde Sean T. Over-the-wire interlock attachment/detachment mechanism
US20020055775A1 (en) * 1999-01-26 2002-05-09 Alain F. Carpentier Flexible heart valve
US6387042B1 (en) * 1998-08-28 2002-05-14 Juan Hernandez Herrero Apparatus aiding physiologic systolic and diastolic dynamics of cardiac cavities
US6406420B1 (en) * 1997-01-02 2002-06-18 Myocor, Inc. Methods and devices for improving cardiac function in hearts
US6506204B2 (en) * 1996-01-24 2003-01-14 Aga Medical Corporation Method and apparatus for occluding aneurysms
US6511496B1 (en) * 2000-09-12 2003-01-28 Advanced Cardiovascular Systems, Inc. Embolic protection device for use in interventional procedures
US20030045896A1 (en) * 2001-02-28 2003-03-06 Chase Medical, Lp Method of using a ventricular restoration shaping apparatus
US20030050685A1 (en) * 1999-08-09 2003-03-13 Nikolic Serjan D. Method for improving cardiac function
US6537198B1 (en) * 2000-03-21 2003-03-25 Myocor, Inc. Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly
US6551303B1 (en) * 1999-10-27 2003-04-22 Atritech, Inc. Barrier device for ostium of left atrial appendage
US6572643B1 (en) * 2000-07-19 2003-06-03 Vascular Architects, Inc. Endoprosthesis delivery catheter assembly and method
US20030105354A1 (en) * 2001-12-05 2003-06-05 Rolf Pinkos Continuous preparation of alkenyl compounds
US20030109770A1 (en) * 1999-08-09 2003-06-12 Sharkey Hugh R. Device with a porous membrane for improving cardiac function
US6652555B1 (en) * 1999-10-27 2003-11-25 Atritech, Inc. Barrier device for covering the ostium of left atrial appendage
US20040002626A1 (en) * 2001-07-16 2004-01-01 Yair Feld In-vivo method and device for improving diastolic function of the left ventricle
US6685627B2 (en) * 1998-10-09 2004-02-03 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence heart function
US20040034366A1 (en) * 1999-11-08 2004-02-19 Ev3 Sunnyvale, Inc., A California Corporation Device for containing embolic material in the LAA having a plurality of tissue retention structures
US20040044361A1 (en) * 1998-11-06 2004-03-04 Frazier Andrew G.C. Detachable atrial appendage occlusion balloon
US20040054394A1 (en) * 2002-09-17 2004-03-18 Don Lee Stent with combined distal protection device
US20040064014A1 (en) * 2001-05-31 2004-04-01 Melvin David B. Devices and methods for assisting natural heart function
US20050007031A1 (en) * 2003-07-11 2005-01-13 Hubbell Incorporated Low voltage luminaire assembly
US20050015109A1 (en) * 2003-07-16 2005-01-20 Samuel Lichtenstein Methods and devices for altering blood flow through the left ventricle
US20050038470A1 (en) * 2003-08-15 2005-02-17 Van Der Burg Erik J. System and method for delivering a left atrial appendage containment device
US20050065548A1 (en) * 2003-09-23 2005-03-24 Marino Joseph A. Right retrieval mechanism
US20050085826A1 (en) * 2003-10-21 2005-04-21 Scimed Life Systems, Inc. Unfolding balloon catheter for proximal embolus protection
US6887192B1 (en) * 2000-09-08 2005-05-03 Converge Medical, Inc. Heart support to prevent ventricular remodeling
US20050096498A1 (en) * 2001-04-24 2005-05-05 Houser Russell A. Sizing and shaping device for treating congestive heart failure
US20050113861A1 (en) * 2003-11-25 2005-05-26 Corcoran Michael P. Left atrial appendage closure device
US20050137690A1 (en) * 2003-12-23 2005-06-23 Sadra Medical Low profile heart valve and delivery system
US20060014998A1 (en) * 2002-08-01 2006-01-19 Sharkey Hugh R Multiple partitioning devices for heart treatment
US20060025800A1 (en) * 2001-09-05 2006-02-02 Mitta Suresh Method and device for surgical ventricular repair
US20060030881A1 (en) * 2004-08-05 2006-02-09 Cardiokinetix, Inc. Ventricular partitioning device
US20060029491A1 (en) * 2002-09-26 2006-02-09 Garrett Norman H Iii Roto-dynamic fluidic systems
US20070135889A1 (en) * 2003-09-03 2007-06-14 Bolton Medical, Inc. Lumen repair device with capture structure
US7485088B2 (en) * 2001-09-05 2009-02-03 Chase Medical L.P. Method and device for percutaneous surgical ventricular repair
US20100121132A1 (en) * 1999-08-09 2010-05-13 Serjan Nikolic Cardiac device and methods of use thereof

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK151404C (en) 1984-05-23 1988-07-18 Cook Europ Aps William Collapsible filter for implantation in a patient's blood vessel
US4710192A (en) 1985-12-30 1987-12-01 Liotta Domingo S Diaphragm and method for occlusion of the descending thoracic aorta
FR2641692B1 (en) 1989-01-17 1995-05-12 Nippon Zeon Co
EP0545091B1 (en) 1991-11-05 1999-07-07 The Children's Medical Center Corporation Occluder for repair of cardiac and vascular defects
FR2689388B1 (en) 1992-04-07 1999-07-16 Celsa Lg blood filter perfects possibly resorbable.
US5766246A (en) 1992-05-20 1998-06-16 C. R. Bard, Inc. Implantable prosthesis and method and apparatus for loading and delivering an implantable prothesis
US6125852A (en) 1993-02-22 2000-10-03 Heartport, Inc. Minimally-invasive devices and methods for treatment of congestive heart failure
US6161543A (en) 1993-02-22 2000-12-19 Epicor, Inc. Methods of epicardial ablation for creating a lesion around the pulmonary veins
US5549621A (en) 1993-05-14 1996-08-27 Byron C. Sutherland Apparatus and method for performing vertical banded gastroplasty
US5791231A (en) 1993-05-17 1998-08-11 Endorobotics Corporation Surgical robotic system and hydraulic actuator therefor
US6258021B1 (en) 1993-06-17 2001-07-10 Peter J. Wilk Intrapericardial assist method
US5843170A (en) 1994-09-02 1998-12-01 Ahn; Sam Seunghae Apparatus and method for performing aneurysm repair
US5797849A (en) 1995-03-28 1998-08-25 Sonometrics Corporation Method for carrying out a medical procedure using a three-dimensional tracking and imaging system
US5578069A (en) 1995-12-06 1996-11-26 Vnetritex, Inc. Electrode deployment mechanism and method using artificial muscle
US5669933A (en) 1996-07-17 1997-09-23 Nitinol Medical Technologies, Inc. Removable embolus blood clot filter
US5833698A (en) 1996-07-23 1998-11-10 United States Surgical Corporation Anastomosis instrument and method
US5861003A (en) 1996-10-23 1999-01-19 The Cleveland Clinic Foundation Apparatus and method for occluding a defect or aperture within body surface
EP0936930B1 (en) 1996-11-05 2004-07-28 Purdue Research Foundation Myocardial graft constructs
US5961440A (en) 1997-01-02 1999-10-05 Myocor, Inc. Heart wall tension reduction apparatus and method
US5961539A (en) 1997-01-17 1999-10-05 Segmed, Inc. Method and apparatus for sizing, stabilizing and/or reducing the circumference of an anatomical structure
US6099832A (en) 1997-05-28 2000-08-08 Genzyme Corporation Transplants for myocardial scars
US6208686B1 (en) * 1997-07-18 2001-03-27 Innova Corporation System and method for dynamic amplitude adjustment of modulating signal in frequency modulated transceivers
US6095968A (en) 1998-04-10 2000-08-01 Cardio Technologies, Inc. Reinforcement device
US6221104B1 (en) 1998-05-01 2001-04-24 Cor Restore, Inc. Anterior and interior segment cardiac restoration apparatus and method
US6547821B1 (en) * 1998-07-16 2003-04-15 Cardiothoracic Systems, Inc. Surgical procedures and devices for increasing cardiac output of the heart
US6093199A (en) 1998-08-05 2000-07-25 Endovascular Technologies, Inc. Intra-luminal device for treatment of body cavities and lumens and method of use
US6102887A (en) 1998-08-11 2000-08-15 Biocardia, Inc. Catheter drug delivery system and method for use
US6152144A (en) 1998-11-06 2000-11-28 Appriva Medical, Inc. Method and device for left atrial appendage occlusion
US7128073B1 (en) * 1998-11-06 2006-10-31 Ev3 Endovascular, Inc. Method and device for left atrial appendage occlusion
US8257428B2 (en) * 1999-08-09 2012-09-04 Cardiokinetix, Inc. System for improving cardiac function
US6482228B1 (en) 2000-11-14 2002-11-19 Troy R. Norred Percutaneous aortic valve replacement
US6592608B2 (en) 2001-12-07 2003-07-15 Biopsy Sciences, Llc Bioabsorbable sealant
US7762943B2 (en) * 2004-03-03 2010-07-27 Cardiokinetix, Inc. Inflatable ventricular partitioning device

Patent Citations (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3874388A (en) * 1973-02-12 1975-04-01 Ochsner Med Found Alton Shunt defect closure system
US4007743A (en) * 1975-10-20 1977-02-15 American Hospital Supply Corporation Opening mechanism for umbrella-like intravascular shunt defect closure device
US4588404A (en) * 1979-01-22 1986-05-13 Didier Lapeyre Total cardiac prosthesis
US4453545A (en) * 1981-05-07 1984-06-12 Hiroshi Inoue Endotracheal tube with movable endobronchial blocker for one-lung anesthesia
US4425908A (en) * 1981-10-22 1984-01-17 Beth Israel Hospital Blood clot filter
US5104399A (en) * 1986-12-10 1992-04-14 Endovascular Technologies, Inc. Artificial graft and implantation method
US5527337A (en) * 1987-06-25 1996-06-18 Duke University Bioabsorbable stent and method of making the same
US4832055A (en) * 1988-07-08 1989-05-23 Palestrant Aubrey M Mechanically locking blood clot filter
US4917089A (en) * 1988-08-29 1990-04-17 Sideris Eleftherios B Buttoned device for the transvenous occlusion of intracardiac defects
US4983165A (en) * 1990-01-23 1991-01-08 Loiterman David A Guidance system for vascular catheter or the like
US5496277A (en) * 1990-04-12 1996-03-05 Schneider (Usa) Inc. Radially expandable body implantable device
US5389087A (en) * 1991-09-19 1995-02-14 Baxter International Inc. Fully exchangeable over-the-wire catheter with rip seam and gated side port
US5425744A (en) * 1991-11-05 1995-06-20 C. R. Bard, Inc. Occluder for repair of cardiac and vascular defects
US5192314A (en) * 1991-12-12 1993-03-09 Daskalakis Michael K Synthetic intraventricular implants and method of inserting
US5860951A (en) * 1992-01-07 1999-01-19 Arthrocare Corporation Systems and methods for electrosurgical myocardial revascularization
US5882340A (en) * 1992-04-15 1999-03-16 Yoon; Inbae Penetrating instrument having an expandable anchoring portion for triggering protrusion of a safety member and/or retraction of a penetrating member
US5527338A (en) * 1992-09-02 1996-06-18 Board Of Regents, The University Of Texas System Intravascular device
US5925062A (en) * 1992-09-02 1999-07-20 Board Of Regents, The University Of Texas System Intravascular device
US5924424A (en) * 1993-02-22 1999-07-20 Heartport, Inc. Method and apparatus for thoracoscopic intracardiac procedures
US5647870A (en) * 1993-03-16 1997-07-15 Ep Technologies, Inc. Multiple electrode support structures
US5385156A (en) * 1993-08-27 1995-01-31 Rose Health Care Systems Diagnostic and treatment method for cardiac rupture and apparatus for performing the same
US5876325A (en) * 1993-11-02 1999-03-02 Olympus Optical Co., Ltd. Surgical manipulation system
US5634942A (en) * 1994-04-21 1997-06-03 B. Braun Celsa Assembly comprising a blood filter for temporary or definitive use and a device for implanting it
US5433727A (en) * 1994-08-16 1995-07-18 Sideris; Eleftherios B. Centering buttoned device for the occlusion of large defects for occluding
US5634936A (en) * 1995-02-06 1997-06-03 Scimed Life Systems, Inc. Device for closing a septal defect
US5867003A (en) * 1995-02-20 1999-02-02 Fujitsu Limited Library apparatus
US5876449A (en) * 1995-04-01 1999-03-02 Variomed Ag Stent for the transluminal implantation in hollow organs
US5925076A (en) * 1995-05-19 1999-07-20 Inoue; Kanji Appliance to be implanted, method of collapsing the appliance to be implanted and method of using the appliance to be implanted
US5865791A (en) * 1995-06-07 1999-02-02 E.P. Technologies Inc. Atrial appendage stasis reduction procedure and devices
US5709707A (en) * 1995-10-30 1998-01-20 Children's Medical Center Corporation Self-centering umbrella-type septal closure device
US6506204B2 (en) * 1996-01-24 2003-01-14 Aga Medical Corporation Method and apparatus for occluding aneurysms
US6355052B1 (en) * 1996-02-09 2002-03-12 Pfm Produkte Fur Die Medizin Aktiengesellschaft Device for closure of body defect openings
US6024756A (en) * 1996-03-22 2000-02-15 Scimed Life Systems, Inc. Method of reversibly closing a septal defect
US6077218A (en) * 1996-10-02 2000-06-20 Acorn Cardiovascular, Inc. Cardiac reinforcement device
US5871017A (en) * 1996-10-15 1999-02-16 Mayer; Paul W. Relative motion cancelling platform for surgery
US5875782A (en) * 1996-11-14 1999-03-02 Cardiothoracic Systems, Inc. Methods and devices for minimally invasive coronary artery revascularization on a beating heart without cardiopulmonary bypass
US5910150A (en) * 1996-12-02 1999-06-08 Angiotrax, Inc. Apparatus for performing surgery
US5879366A (en) * 1996-12-20 1999-03-09 W.L. Gore & Associates, Inc. Self-expanding defect closure device and method of making and using
US6406420B1 (en) * 1997-01-02 2002-06-18 Myocor, Inc. Methods and devices for improving cardiac function in hearts
US6045497A (en) * 1997-01-02 2000-04-04 Myocor, Inc. Heart wall tension reduction apparatus and method
US6059715A (en) * 1997-01-02 2000-05-09 Myocor, Inc. Heart wall tension reduction apparatus
US5928260A (en) * 1997-07-10 1999-07-27 Scimed Life Systems, Inc. Removable occlusion system for aneurysm neck
US5865730A (en) * 1997-10-07 1999-02-02 Ethicon Endo-Surgery, Inc. Tissue stabilization device for use during surgery having remotely actuated feet
US6036720A (en) * 1997-12-15 2000-03-14 Target Therapeutics, Inc. Sheet metal aneurysm neck bridge
US6221092B1 (en) * 1998-03-30 2001-04-24 Nissho Corporation Closure device for transcatheter operations and catheter assembly therefor
US6024096A (en) * 1998-05-01 2000-02-15 Correstore Inc Anterior segment ventricular restoration apparatus and method
US20020026092A1 (en) * 1998-05-01 2002-02-28 Buckberg Gerald D. Ventricular restoration patch
US6077214A (en) * 1998-07-29 2000-06-20 Myocor, Inc. Stress reduction apparatus and method
US5916145A (en) * 1998-08-07 1999-06-29 Scimed Life Systems, Inc. Device and method of using a surgical assembly with mesh sheath
US6387042B1 (en) * 1998-08-28 2002-05-14 Juan Hernandez Herrero Apparatus aiding physiologic systolic and diastolic dynamics of cardiac cavities
US6360749B1 (en) * 1998-10-09 2002-03-26 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence heart function
US6685627B2 (en) * 1998-10-09 2004-02-03 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence heart function
US6193731B1 (en) * 1998-10-27 2001-02-27 Fziomed, Inc. Laparoscopic insertion and deployment device
US20040044361A1 (en) * 1998-11-06 2004-03-04 Frazier Andrew G.C. Detachable atrial appendage occlusion balloon
US6364896B1 (en) * 1998-11-24 2002-04-02 Embol-X, Inc. Compliant framework and methods of use
US6076013A (en) * 1999-01-14 2000-06-13 Brennan; Edward F. Apparatus and methods for treating congestive heart failure
US20020055775A1 (en) * 1999-01-26 2002-05-09 Alain F. Carpentier Flexible heart valve
US6348068B1 (en) * 1999-07-23 2002-02-19 Sulzer Carbomedics Inc. Multi-filament valve stent for a cardisc valvular prosthesis
US20100121132A1 (en) * 1999-08-09 2010-05-13 Serjan Nikolic Cardiac device and methods of use thereof
US20030050682A1 (en) * 1999-08-09 2003-03-13 Sharkey Hugh R. Device for improving cardiac function
US20030109770A1 (en) * 1999-08-09 2003-06-12 Sharkey Hugh R. Device with a porous membrane for improving cardiac function
US20030050685A1 (en) * 1999-08-09 2003-03-13 Nikolic Serjan D. Method for improving cardiac function
US6852076B2 (en) * 1999-08-09 2005-02-08 Cardiokinetix, Inc. Method for improving cardiac function
US6231561B1 (en) * 1999-09-20 2001-05-15 Appriva Medical, Inc. Method and apparatus for closing a body lumen
US20030120337A1 (en) * 1999-10-27 2003-06-26 Atritech, Inc. Barrier device for ostium of left atrial appendage
US6551303B1 (en) * 1999-10-27 2003-04-22 Atritech, Inc. Barrier device for ostium of left atrial appendage
US6652555B1 (en) * 1999-10-27 2003-11-25 Atritech, Inc. Barrier device for covering the ostium of left atrial appendage
US6730108B2 (en) * 1999-10-27 2004-05-04 Atritech, Inc. Barrier device for ostium of left atrial appendage
US20040034366A1 (en) * 1999-11-08 2004-02-19 Ev3 Sunnyvale, Inc., A California Corporation Device for containing embolic material in the LAA having a plurality of tissue retention structures
US20020028981A1 (en) * 1999-12-23 2002-03-07 Lilip Lau Expandable cardiac harness for treating congestive heart failure
US20020019580A1 (en) * 2000-03-10 2002-02-14 Lilip Lau Expandable cardiac harness for treating congestive heart failure
US6537198B1 (en) * 2000-03-21 2003-03-25 Myocor, Inc. Splint assembly for improving cardiac function in hearts, and method for implanting the splint assembly
US6334864B1 (en) * 2000-05-17 2002-01-01 Aga Medical Corp. Alignment member for delivering a non-symmetric device with a predefined orientation
US6572643B1 (en) * 2000-07-19 2003-06-03 Vascular Architects, Inc. Endoprosthesis delivery catheter assembly and method
US6343605B1 (en) * 2000-08-08 2002-02-05 Scimed Life Systems, Inc. Percutaneous transluminal myocardial implantation device and method
US6887192B1 (en) * 2000-09-08 2005-05-03 Converge Medical, Inc. Heart support to prevent ventricular remodeling
US6511496B1 (en) * 2000-09-12 2003-01-28 Advanced Cardiovascular Systems, Inc. Embolic protection device for use in interventional procedures
US20020032481A1 (en) * 2000-09-12 2002-03-14 Shlomo Gabbay Heart valve prosthesis and sutureless implantation of a heart valve prosthesis
US20020055767A1 (en) * 2000-10-18 2002-05-09 Forde Sean T. Over-the-wire interlock attachment/detachment mechanism
US20030045896A1 (en) * 2001-02-28 2003-03-06 Chase Medical, Lp Method of using a ventricular restoration shaping apparatus
US6994093B2 (en) * 2001-02-28 2006-02-07 Chase Medical, L.P. Ventricular restoration shaping apparatus and method of use
US20050096498A1 (en) * 2001-04-24 2005-05-05 Houser Russell A. Sizing and shaping device for treating congestive heart failure
US20040064014A1 (en) * 2001-05-31 2004-04-01 Melvin David B. Devices and methods for assisting natural heart function
US20040002626A1 (en) * 2001-07-16 2004-01-01 Yair Feld In-vivo method and device for improving diastolic function of the left ventricle
US20060025800A1 (en) * 2001-09-05 2006-02-02 Mitta Suresh Method and device for surgical ventricular repair
US7485088B2 (en) * 2001-09-05 2009-02-03 Chase Medical L.P. Method and device for percutaneous surgical ventricular repair
US20030105354A1 (en) * 2001-12-05 2003-06-05 Rolf Pinkos Continuous preparation of alkenyl compounds
US20060014998A1 (en) * 2002-08-01 2006-01-19 Sharkey Hugh R Multiple partitioning devices for heart treatment
US20040054394A1 (en) * 2002-09-17 2004-03-18 Don Lee Stent with combined distal protection device
US20060029491A1 (en) * 2002-09-26 2006-02-09 Garrett Norman H Iii Roto-dynamic fluidic systems
US20050007031A1 (en) * 2003-07-11 2005-01-13 Hubbell Incorporated Low voltage luminaire assembly
US20050015109A1 (en) * 2003-07-16 2005-01-20 Samuel Lichtenstein Methods and devices for altering blood flow through the left ventricle
US20050038470A1 (en) * 2003-08-15 2005-02-17 Van Der Burg Erik J. System and method for delivering a left atrial appendage containment device
US20070135889A1 (en) * 2003-09-03 2007-06-14 Bolton Medical, Inc. Lumen repair device with capture structure
US20050065548A1 (en) * 2003-09-23 2005-03-24 Marino Joseph A. Right retrieval mechanism
US20050085826A1 (en) * 2003-10-21 2005-04-21 Scimed Life Systems, Inc. Unfolding balloon catheter for proximal embolus protection
US20050113861A1 (en) * 2003-11-25 2005-05-26 Corcoran Michael P. Left atrial appendage closure device
US20050137690A1 (en) * 2003-12-23 2005-06-23 Sadra Medical Low profile heart valve and delivery system
US20060030881A1 (en) * 2004-08-05 2006-02-09 Cardiokinetix, Inc. Ventricular partitioning device
US20080071298A1 (en) * 2004-08-05 2008-03-20 Alexander Khairkhahan Laminar ventricular partitioning device

Cited By (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8834519B2 (en) 1998-11-06 2014-09-16 Artritech, Inc. Method and device for left atrial appendage occlusion
US8377114B2 (en) 1999-08-09 2013-02-19 Cardiokinetix, Inc. Sealing and filling ventricular partitioning devices to improve cardiac function
US8388672B2 (en) 1999-08-09 2013-03-05 Cardiokinetix, Inc. System for improving cardiac function by sealing a partitioning membrane within a ventricle
US8500790B2 (en) 1999-08-09 2013-08-06 Cardiokinetix, Inc. Retrievable cardiac devices
US8672827B2 (en) 1999-08-09 2014-03-18 Cardiokinetix, Inc. Cardiac device and methods of use thereof
US9017394B2 (en) 1999-08-09 2015-04-28 Cardiokinetix, Inc. Retrievable cardiac devices
US9872767B2 (en) 1999-08-09 2018-01-23 Edwards Lifesciences Corporation Retrievable cardiac devices
US9694121B2 (en) 1999-08-09 2017-07-04 Cardiokinetix, Inc. Systems and methods for improving cardiac function
US10064696B2 (en) 2000-08-09 2018-09-04 Edwards Lifesciences Corporation Devices and methods for delivering an endocardial device
US9078660B2 (en) 2000-08-09 2015-07-14 Cardiokinetix, Inc. Devices and methods for delivering an endocardial device
US8827892B2 (en) 2002-08-01 2014-09-09 Cardiokinetix, Inc. Therapeutic methods and devices following myocardial infarction
US9592123B2 (en) 2002-08-01 2017-03-14 Cardiokinetix, Inc. Therapeutic methods and devices following myocardial infarction
US9332993B2 (en) 2004-08-05 2016-05-10 Cardiokinetix, Inc. Devices and methods for delivering an endocardial device
US9332992B2 (en) 2004-08-05 2016-05-10 Cardiokinetix, Inc. Method for making a laminar ventricular partitioning device
US9039597B2 (en) 2009-10-26 2015-05-26 Cardiokinetix, Inc. Ventricular volume reduction
US10028835B2 (en) 2009-10-26 2018-07-24 Edwards Lifesciences Corporation Ventricular volume reduction
US9364327B2 (en) 2009-10-26 2016-06-14 Cardiokinetix, Inc. Ventricular volume reduction
US8956380B2 (en) 2010-10-18 2015-02-17 Apollo Endosurgery, Inc. Reactive intragastric implant devices
US9795498B2 (en) 2010-10-18 2017-10-24 Apollo Endosurgery Us, Inc. Intragastric balloon for treating obesity
US9668901B2 (en) 2010-10-18 2017-06-06 Apollo Endosurgery Us, Inc. Intragastric implants with duodenal anchors
US9463107B2 (en) 2010-10-18 2016-10-11 Apollo Endosurgery, Inc. Variable size intragastric implant devices
US8870966B2 (en) 2010-10-18 2014-10-28 Apollo Endosurgery, Inc. Intragastric balloon for treating obesity
US20120095499A1 (en) * 2010-10-19 2012-04-19 Allergan, Inc. Upper stomach gastric implants
US9539133B2 (en) 2010-10-19 2017-01-10 Apollo Endosurgery, Inc. Stomach-spanning gastric implants
US9498365B2 (en) 2010-10-19 2016-11-22 Apollo Endosurgery, Inc. Intragastric implants with multiple fluid chambers
US9398969B2 (en) 2010-10-19 2016-07-26 Apollo Endosurgery, Inc. Upper stomach gastric implants
US9681974B2 (en) 2010-10-19 2017-06-20 Apollo Endosurgery Us, Inc. Intragastric implants with collapsible frames
US9198790B2 (en) * 2010-10-19 2015-12-01 Apollo Endosurgery, Inc. Upper stomach gastric implants
US8920447B2 (en) 2010-10-19 2014-12-30 Apollo Endosurgery, Inc. Articulated gastric implant clip
US9801747B2 (en) 2010-10-19 2017-10-31 Apollo Endosurgery Us, Inc. Non-inflatable gastric implants and systems
US8864840B2 (en) 2010-10-19 2014-10-21 Apollo Endosurgery, Inc. Intragastric implants with collapsible frames
US10070980B2 (en) 2010-10-19 2018-09-11 Apollo Endosurgery Us, Inc. Anchored non-piercing duodenal sleeve and delivery systems
CN105476733A (en) * 2016-01-27 2016-04-13 张刚成 Ventricular volume reduction means
CN106344081A (en) * 2016-09-28 2017-01-25 宁波迪创医疗科技有限公司 Volume reduction mechanism for left ventricle

Also Published As

Publication number Publication date Type
US7399271B2 (en) 2008-07-15 grant
WO2005070330A1 (en) 2005-08-04 application
EP1708642A1 (en) 2006-10-11 application
CA2559320C (en) 2012-10-09 grant
JP4519858B2 (en) 2010-08-04 grant
US20050154252A1 (en) 2005-07-14 application
CA2559320A1 (en) 2005-08-04 application
JP2007517596A (en) 2007-07-05 application

Similar Documents

Publication Publication Date Title
US6447539B1 (en) Method and apparatus for treating ischemic heart disease by providing transvenous myocardial perfusion
US6432039B1 (en) Methods and apparatus for reinforcement of the heart ventricles
US6959711B2 (en) Kit and method for use during ventricular restoration
US7128073B1 (en) Method and device for left atrial appendage occlusion
US20050228422A1 (en) Devices, systems, and methods for reshaping a heart valve annulus, including the use of magnetic tools
US20050070952A1 (en) Device and methods for preventing formation of thrombi in the left atrial appendage
US7485088B2 (en) Method and device for percutaneous surgical ventricular repair
US20050222488A1 (en) Devices, systems, and methods for reshaping a heart valve annulus
US8163013B2 (en) Devices, systems, and methods for reshaping a heart valve annulus, including the use of magnetic tools
US7674222B2 (en) Cardiac device and methods of use thereof
US20060069430A9 (en) Devices, systems, and methods for retaining a native heart valve leaflet
US6994092B2 (en) Device for containing embolic material in the LAA having a plurality of tissue retention structures
US5180366A (en) Apparatus and method for angioplasty and for preventing re-stenosis
US20020029037A1 (en) Method and apparatus for percutaneous trans-endocardial reperfusion
US20090326648A1 (en) Devices, systems, and methods for reshaping a heart valve annulus, including the use of an adjustable bridge implant system
US20050234540A1 (en) Dilatation systems and methods for left atrial appendage
US20060106279A1 (en) Devices, systems, and methods for reshaping a heart valve annulus, including the use of a bridge implant having an adjustable bridge stop
US6343605B1 (en) Percutaneous transluminal myocardial implantation device and method
US20080091264A1 (en) Devices, systems, and methods for reshaping a heart valve annulus, including the use of magnetic tools
US20020133227A1 (en) Ventricular restoration patch apparatus and method of use
US20050222489A1 (en) Devices, systems, and methods for reshaping a heart valve annulus, including the use of a bridge implant
US7785248B2 (en) Steerable lesion excluding heart implants for congestive heart failure
US20070208210A1 (en) Method and apparatus to unload a failing heart
US20090099596A1 (en) Closure device for left atrial appendage
US20070078297A1 (en) Device for Treating Mitral Valve Regurgitation

Legal Events

Date Code Title Description
AS Assignment

Owner name: CARDIOKINETIX, INC., CALIFORNIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SHARKEY, HUGH R.;KHAIRKHAHAN, ALEXANDER;NIKOLIC, SERJAN D.;AND OTHERS;REEL/FRAME:023004/0773;SIGNING DATES FROM 20040420 TO 20040424

AS Assignment

Owner name: SILICON VALLEY BANK,CALIFORNIA

Free format text: SECURITY AGREEMENT;ASSIGNOR:CARDLOKINETIX, INC.;REEL/FRAME:024539/0631

Effective date: 20100614

Owner name: SILICON VALLEY BANK, CALIFORNIA

Free format text: SECURITY AGREEMENT;ASSIGNOR:CARDIOKINETIX, INC.;REEL/FRAME:024539/0631

Effective date: 20100614

AS Assignment

Owner name: CARDIOKINETIX, INC., CALIFORNIA

Free format text: RELEASE;ASSIGNOR:SILICON VALLEY BANK;REEL/FRAME:027504/0897

Effective date: 20111228

AS Assignment

Owner name: CARDIOKINETIX, INC., CALIFORNIA

Free format text: RELEASE;ASSIGNOR:SILICON VALLEY BANK;REEL/FRAME:029993/0546

Effective date: 20130307

AS Assignment

Owner name: CARDIOKINETIX (ASSIGNMENT FOR THE BENEFIT OF CREDI

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:CARDIOKINETIX, INC.;REEL/FRAME:044599/0682

Effective date: 20170626

AS Assignment

Owner name: EDWARDS LIFESCIENCES CORPORATION, CALIFORNIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:CARDIOKINETIX (ASSIGNMENT FOR THE BENEFIT OF CREDITORS), LLC;REEL/FRAME:044348/0922

Effective date: 20170921