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US20080208356A1 - Satiation devices and methods - Google Patents

Satiation devices and methods Download PDF

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Publication number
US20080208356A1
US20080208356A1 US11958587 US95858707A US2008208356A1 US 20080208356 A1 US20080208356 A1 US 20080208356A1 US 11958587 US11958587 US 11958587 US 95858707 A US95858707 A US 95858707A US 2008208356 A1 US2008208356 A1 US 2008208356A1
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Patent type
Prior art keywords
pouch
fig
stomach
distal
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11958587
Inventor
Richard S. Stack
Richard A. Glenn
William L. Athas
Michael S. Williams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Barosense Inc
Original Assignee
Stack Richard S
Glenn Richard A
Athas William L
Williams Michael S
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013Implantable devices or invasive measures
    • A61F5/0076Implantable devices or invasive measures preventing normal digestion, e.g. Bariatric or gastric sleeves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013Implantable devices or invasive measures
    • A61F5/0036Intragastrical devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/24Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2002/044Oesophagi or esophagi or gullets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2002/045Stomach, intestines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2002/065Y-shaped blood vessels
    • A61F2002/067Y-shaped blood vessels modular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/848Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs
    • A61F2002/8483Barbs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0067Three-dimensional shapes conical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0039Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in diameter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices; Anti-rape devices
    • A61F5/0003Apparatus for the treatment of obesity; Anti-eating devices
    • A61F5/0013Implantable devices or invasive measures
    • A61F5/0076Implantable devices or invasive measures preventing normal digestion, e.g. Bariatric or gastric sleeves
    • A61F5/0079Pyloric or esophageal obstructions

Abstract

A device for inducing weight loss in a patient includes a tubular prosthesis positionable at the gastro-esophageal junction region, preferably below the z-line. In a method for inducing weight loss, the prosthesis is placed such that an opening at its proximal end receives masticated food from the esophagus, and such that the masticated food passes through the pouch and into the stomach via an opening in its distal end.

Description

    PRIORITY
  • [0001]
    This application is a continuation of U.S. patent application Ser. No. 10/751,751, filed Jan. 5, 2004, which claims the benefit of U.S. patent application Ser. No. 10/118,289, filed Apr. 8, 2002, which is a continuation-in-part of U.S. patent application Ser. No. 09/940,110, filed Aug. 27, 2001. claims the benefit of U.S. application Ser. No. 09/940,110, filed Aug. 27, 2001.
  • FIELD OF THE INVENTION
  • [0002]
    The present invention relates generally to the field of devices and methods for achieving weight loss in humans, and specifically to the use of devices implantable within the human stomach for controlling feelings of hunger.
  • BACKGROUND OF THE INVENTION
  • [0003]
    Various medical approaches are used for controlling obesity. These approaches include diet, medication, and surgical procedures. One of the more successful surgical procedures is the vertical banded gastroplexy or the proximal gastric pouch with a Roux-en-Y anastomosis that shunts food from the proximal region of the stomach into the intestine, thereby minimizing absorption of food into the bloodstream. However, known complications are present with each of these procedures and more successful options are desired.
  • [0004]
    Other alternatives include implantation of gastric balloons that prevent overeating by occupying volume within the stomach. Unfortunately, gastric balloons can migrate down the GI tract, causing obstruction and thus necessitating removal.
  • [0005]
    It is therefore desirable to provide a successful and minimally-invasive alternative to existing approaches for controlling obesity.
  • SUMMARY OF THE INVENTION
  • [0006]
    A satiation device utilizing principles of the present invention includes a tubular pouch positionable at the gastro-esophageal junction. The pouch has a proximal opening for receiving ingested food from the esophagus, and a distal opening for releasing food from the pouch into the stomach. The pouch is proportioned such that release of food from the pouch in to the stomach occurs relatively slowly, causing food to accumulate within the pouch so as to give the patient the sensation of fullness.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0007]
    FIG. 1 is a schematic illustration of a human stomach and a portion of the small intestine.
  • [0008]
    FIG. 2 is a schematic illustration similar to FIG. 1 showing in vivo positioning of a stomach pouch.
  • [0009]
    FIG. 3 is a cross-sectional side elevation view of a delivery system which may be used to deliver a satiation device such as the pouch of FIG. 2.
  • [0010]
    FIG. 4A is a cross-sectional end view of the pusher tube of the delivery system of FIG. 3.
  • [0011]
    FIG. 4B is an alternative cross-sectional end view of a pusher tube that may be used for the delivery system of FIG. 3.
  • [0012]
    FIG. 5 is a cross-sectional side elevation view of the delivery system of FIG. 3 during delivery of a pouch into the gastro-esophageal junction.
  • [0013]
    FIG. 6 further illustrates delivery of a pouch into the gastro-esophageal junction. The delivery system is not shown to allow the pouch and sutures to be seen more easily.
  • [0014]
    FIG. 7 illustrates final positioning of the pouch of FIG. 6.
  • [0015]
    FIG. 8 is a perspective view of an alternative pouch which uses a sewing ring.
  • [0016]
    FIGS. 9A and 9B are a perspective view and a top plan view, respectively, of an alternative pouch using a sewing ring.
  • [0017]
    FIG. 10 is yet another alternative embodiment of a pouch utilizing a sewing ring, and illustrates an alternative pouch shape.
  • [0018]
    FIG. 11 is a schematic illustration showing positioning of a pouch utilizing a sewing ring as positioned at the gastro-esophageal junction.
  • [0019]
    FIG. 12 is a schematic illustration, similar to FIG. 11, showing an alternative pouch which includes a separately implantable sewing ring.
  • [0020]
    FIGS. 13A and 13B are a schematic illustrations showing use of a coaxial plication device, in which FIG. 13A shows positioning of the catheter after the ring has been positioned and FIG. 13B shows formation of the plication and placement of the locking ring.
  • [0021]
    FIG. 14A is a schematic illustration showing an alternative plication device. FIG. 14B is a perspective view showing plication of tissue using the device of FIG. 14A.
  • [0022]
    FIG. 15 is a perspective view of an inflatable pouch.
  • [0023]
    FIG. 16 is a schematic illustration showing delivery of the pouch of FIG. 15 using a delivery device.
  • [0024]
    FIG. 17 illustrates in vivo positioning of an alternative stomach pouch.
  • [0025]
    FIG. 18A is a perspective view of the stomach pouch of FIG. 17 within a positioning sheath used for delivery.
  • [0026]
    FIG. 18B is a perspective view of the stomach pouch of FIG. 17 during deployment. The pouch is shown released from the positioning sheath but still coupled to the mandrel.
  • [0027]
    FIG. 19 is a perspective view of yet another embodiment of a stomach pouch.
  • [0028]
    FIG. 20A is a perspective view of yet another alternative stomach pouch, which utilizes a coil configuration.
  • [0029]
    FIG. 20B is a cross-sectional side view of the stomach pouch of FIG. 20A
  • [0030]
    FIG. 21A is a schematic illustration illustrating a fundal cage in combination with a stomach pouch.
  • [0031]
    FIG. 21B is a schematic illustration similar to FIG. 21A but further illustrating an alignment extension in combination with the stomach pouch and cage.
  • [0032]
    FIG. 22A shows yet another alternative of a stomach pouch embodiment.
  • [0033]
    FIG. 22B is a cross-section view of a side-wall of the stomach pouch of FIG. 22A.
  • [0034]
    FIG. 22C is a perspective view of a distal chute region of the stomach pouch of FIG. 22A.
  • [0035]
    FIG. 22D is a perspective view of a distal chute region alternative to the distal chute region of FIG. 22C.
  • [0036]
    FIG. 23 is an alternative delivery device that may be used to deliver a stomach pouch.
  • [0037]
    FIGS. 24A and 24B are end views of the delivery device of FIG. 23, showing the claws in the opened and closed positions, respectively.
  • [0038]
    FIGS. 25A and 25B are a sequence of side elevation views showing engagement of a satiation device by the delivery device prior to implantation using the delivery device.
  • [0039]
    FIG. 26 shows a perspective view of still another stomach pouch.
  • [0040]
    FIGS. 27A and 27B are top plan views showing a ring of the type used in the embodiment of FIG. 26. The ring is shown in the compressed position in FIG. 27A and in the natural, expanded, position in FIG. 27B.
  • [0041]
    FIG. 28A is a perspective view of still another embodiment of a satiation pouch.
  • [0042]
    FIG. 28B is a schematic illustration of in vivo positioning of the pouch of FIG. 28A.
  • [0043]
    FIG. 29 illustrates in vivo positioning of a trans-esophageal pouch.
  • [0044]
    FIG. 30 illustrates in vivo positioning of an alternative trans-esophageal pouch.
  • [0045]
    FIG. 31 is a front elevation view of a satiation pouch having an adjustable distal opening.
  • [0046]
    FIG. 32A is a front elevation view of a satiation pouch having an alternative form of adjustable distal opening.
  • [0047]
    FIG. 32B is a top plan view of the adjustable restrictor ring of the pouch of FIG. 32A.
  • [0048]
    FIG. 33 is a side elevation view of a satiation pouch having yet another form of adjustable distal opening, and a tool useable for adjusting the distal opening.
  • [0049]
    FIGS. 34A and 34B are side elevation views showing the distal end of the tool shown in FIG. 33 in the retracted and expanding positions, respectively.
  • [0050]
    FIGS. 35A and 35B are top plan views of the adjustable restrictor ring of the pouch of FIG. 33, showing the ring in expanded and contracted positions.
  • [0051]
    FIGS. 36A through 36D are a series of figures schematically illustrating removal of a satiation pouch from a patient.
  • [0052]
    FIG. 37 is a cross-sectional side elevation view of a pouch extraction tool that may be used in combination with the tools shown in FIGS. 36A-36D.
  • [0053]
    FIGS. 38A and 38B are schematic illustrations of a stomach and esophagus, illustrating a satiation pouch having a safety leash.
  • DETAILED DESCRIPTION
  • [0054]
    An anatomical view of a human stomach S and associated features is shown in FIG. 1. The esophagus E delivers food from the mouth to the stomach S. The z-line or gastro-esophageal junction Z is the irregularly-shaped border between the thin tissue of the esophagus and the thicker tissue of the stomach wall. The gastro-esophageal junction region G is the region encompassing the distal portion of the esophagus E, the z-line, and the proximal portion of the stomach S.
  • [0055]
    Various embodiments of satiation devices are described herein. Many of these devices include a pouch or funnel positioned at the gastro-esophageal junction region so as to form a small reservoir which collects masticated food from the esophagus—thereby limiting the amount of food that can be consumed at one time. Over time the food within this reservoir descends into the stomach through a distal opening in the pouch. The pouch may optionally include a tubular extension positionable within the esophagus to facilitate flow of food from the esophagus into the pouch.
  • [0056]
    Materials that may be used for the pouch include flexible materials that will prevent passage of food through the sides of the pouch. Examples of such materials include, but are not limited to polyesters (e.g., Dacron® polyester), ePTFE fabric (e.g., GoreTex® fabric or others), a polyurethane such as ChronoFlex® polyurethane, nylon fabrics, silicone, other polymeric materials, and bio-absorbable materials (e.g., PLLA, PGA, PCL, poly-amhydride, etc). The pouch 12 may be formed of a composite of compliant, semi-compliant and/or non-compliant materials which give different regions of the pouch different degrees of compliance so as to allow/limit expansion of the pouch in various locations. For example, it may be desirable to provide the pouch with a fairly elastic exit port to as to prevent occlusion in the event a large piece of food is ingested, whereas the proximal end of the pouch may be stiffer to prevent bulging. Varying degrees of compliance may also be built into the pouch by varying the cross-sectional thickness of the pouch in different regions of the pouch. The pouch material may be coated with a lubricious, bio-compatible, chemically inert material, such as paraleyne, to reduce friction on the base.
  • [0057]
    The flexible pouch material may be carried by a supporting structure, such as a soft mesh, coil, a cage structure, ribs, rings etc. The supporting structure may be formed of stainless steel, polymer, shape memory materials (such as nitinol, shape memory alloys, or shape memory polymers), bio-absorbable materials or, in the case of a silicone pouch, thickened regions of silicone. The supporting structure may be located at the interior or exterior of the flexible pouch material. It may be molded into or sewn to the pouch material, or it may be attached using a suitable adhesive. If a tightly woven mesh or tightly wound coil is provided, the flexible pouch material may be eliminated. Alternatively, a mesh may be provided having a polymeric material embedded in the interstices of the mesh, in which case a separate internal or external covering of pouch material may be eliminated.
  • [0058]
    The pouch is preferably constructed so as to be self-expanding, such that the pouch springs radially open into an expanded condition upon ejection from a deployment device or catheter as more fully described below.
  • [0059]
    In many of the embodiments, the pouch is formed to have a funnel shape. However, a variety of alternative shapes may be used for the pouch. For example, the pouch may have a much shorter proximal-to-distal dimension and thus take the shape of a shallow saucer with a small hole on its bottom surface. Other examples include, but are not limited to, egg shapes, other tapered shapes such as the shape of a “spinning top”, cylindrical shapes, and other symmetrical or asymmetrical shapes.
  • [0060]
    The device may be modular in that where multiple components are to be implanted, the various components may be provided separately from one another. In such a modular system, the separately implanted components may be attached to one another within the body during implantation, or certain ones of them may remain unattached to one another even after implantation. Alternatively, the physician may assemble the components to one another just prior to implantation. Modular components are desirable in that they permit the physician to select sizes for each component that are appropriate for the patient.
  • [0061]
    One embodiment of a satiation device is illustrated in FIG. 2 and includes a pouch 12 that is positioned in the proximal region of the stomach. Pouch 12 includes a proximal opening 14 that is positionable at the gastro-esophageal junction region (and preferably below the z-line) as shown, and a distal opening 16 that opens into the interior of the stomach S. In this embodiment, the pouch 12 tapers outwardly from the proximal opening to form an apron 18, and then tapers inwardly towards the distal opening 16 to give the distal portion of the pouch 12 a funnel shape. However, a variety of alternative shapes may be used for the pouch. For example, the pouch may have a much shorter proximal-to-distal dimension and thus take the shape of a shallow saucer with a small hole on its bottom surface.
  • [0062]
    Because of its small volume (which may be on the order of approximately 2 cc-300 cc in volume, but is preferably in the range of 10-30 cc), the pouch functions to limit the amount of food that can be consumed at one time.
  • [0063]
    Pouch 12 may be formed of a flexible material that will prevent passage of food through the sides of the pouch, such as Dacron® polyester, silicone, or other polymeric material. The pouch 12 may be formed of a composite of compliant, semi-compliant and/or non-compliant materials which give different regions of the pouch different degrees of compliance. Such a composite would allow/limit expansion of the pouch in various locations, so as to help control the passage rate of food material through the pouch and/or the exit pressure of the food from the pouch. If silicone is used, varying degrees of compliance may be built into the pouch by varying the cross-sectional thickness of the pouch in different regions of the pouch. The pouch material may be coated with a lubricious, bio-compatible, chemically inert material, such as paraleyne, to reduce friction on the base material's surface which will help prevent sticking and food build up on the device.
  • [0064]
    During implantation the pouch 12 is secured at the gastro-esophageal junction region G using sutures, clips, adhesives or other suitable means. Although the pouch may be secured to the esophageal tissue, it is more preferable to apply sutures/clips below the Z-line to allow for attachment to the thicker tissue of the stomach wall. Suture attachment points, which may take the form of holes, eyelets or grommets 20 in the pouch may be used to provide reinforced regions for anchoring the sutures. Although as few or as many of such suture/clip attachment points as needed may be used, at least four such points are desirable, such as at 90° intervals around the pouch, so as to enable the pouch to be secured around the full circumference of the tissue. The suture attachment points may be made of a suitably dense radio-opaque material, such as titanium or gold, to add in visualization of the device during or after the procedure. Each suture attachment point may also be marked using a different color to facilitate identification and orientation of sutures. If the pouch is formed of silicone, the proximal portion of the pouch (in which the eyelets 20 are located) may be formed of more durable material such as a woven material, Dacron® polyester or ePTFE fabric in lieu of silicone so as to provide a more durable sewing region. Although grommets, eyelets or reinforced regions may be advantageous, the pouch may alternatively be provided without suture attachment points formed of special materials (with or without identifying markings)—in which case the sutures are passed directly through the pouch material.
  • [0065]
    The flexible pouch material may be carried by supporting members, such as a soft mesh, a cage structure, ribs, rings etc. The supporting members may be formed of stainless steel, polymer, shape memory materials such as nitinol, shape memory alloys, or shape memory polymers, or thickened regions of pouch material. The pouch is preferably constructed so as to be self-expanding, such that the pouch springs radially open into an expanded condition upon ejection from a deployment device or catheter as more fully described below.
  • [0066]
    FIG. 3 shows a delivery system 22 of a type that may be used to implant the pouch 12 as well as any of the other satiation devices described herein. Delivery system 22 includes an elongate tubular sheath 24 and a pusher tube 26 slidably received within the sheath. Sheath 24 includes a distal end 28 that is slightly tapered and formed of a flexible material such as a low durometer polyethylene so as to minimize trauma to body tissues contacted by the end 28 during its movement into and within the esophagus and stomach.
  • [0067]
    Pusher tube 26 is an elongate tube extending through the sheath 24 and extending slightly from the proximal end of the sheath 24. A handle 30 may be formed at the proximal end of the pusher tube 26 to facilitate movement of the pusher tube relative to the sheath 24. Pusher tube 26 includes a central lumen 32 for receiving devices that may be needed at the implantation site. Such devices may include, for example, an endoscope 34 to provide visualization of the implant procedure, or other devices if needed to ensure proper placement of the implant. A plurality of circumferential lumen 36 (FIG. 4A) and/or grooves 38 (FIG. 4B) are positioned circumferentially in the pusher tube 26. During use, suture strands may be positioned within these lumen/grooves so as to keep the strands separated from one another.
  • [0068]
    Referring to FIG. 5, in preparation for implantation of pouch 12, suture strands 40 are secured to the eyelets 20 of the pouch, and the pouch is folded or rolled and placed in the distal end of sheath 24. A proximal end of each suture strand is drawn out the proximal end of the sheath 24 and threaded through lumen 36 (FIG. 4A) or slots 36 (FIG. 4B) of pusher tube 26. A distal end of each suture strand is drawn out the distal end of the sheath 24. The suture strands may be of different colors or have different colored patterns—which may correspond to the colors of the suture points on the pouch, so as to allow ease of identification and keep the sutures distinguishable from each other. Next, pusher tube 26 is passed into the sheath 24 such that its distal end faces the folded pouch 12.
  • [0069]
    The distal end of sheath 24 is passed through the esophagus and into the stomach. The free distal ends of the suture strands 40 are sewn through the tissue surrounding the esophageal opening, preferably just below the Z line. The sutures may be attached under endoscopic guidance if desired, using conventional suturing techniques. See FIGS. 5 and 6. The sheath 24 is not shown in FIG. 6 so that the funnel and sutures can more clearly be shown.
  • [0070]
    Once the sutures have been secured to the tissue, the pusher tube 26 is advanced in a distal direction using handle 30. Pusher tube 26 drives the pouch 12 out the distal opening of the sheath 24. The sheath 24 is positioned with the eyelets 20 at the suture location as shown in FIG. 7. A knot 42 is tied in each suture and slid down the length of the sutures to the tissue, thereby fastening the pouch in place.
  • [0071]
    Once implanted, the pouch limits passage of food from the patient's esophagus into the stomach. It is believed that as food collects and backs up in the reservoir of the pouch, baroreceptors in the fundus of the stomach and in the gastro-esophageal junction region will trigger a feeling of satiation. Gravity and columnar force will propel food through the reservoir's restricted orifice and into the stomach where normal digestion will occur.
  • [0072]
    FIG. 8 shows a second embodiment of a pouch 44. Pouch 44 includes an elastomeric or semi-compliant material (such as, for example, a durable polyurethane elastomer such as ChronoFlex® polyurethane, silicone, ePTFE mesh or fabric, Dacron® mesh or fabric). The pouch may alternatively be formed of a composite of compliant (or semi-compliant) and non-compliant materials so as to incorporate regions of varying compliance into the pouch. Pouch 44 may include a reinforcing structure such as a helical rib or ring 46—which may be formed of nitinol, stainless steel, plastic etc. The reinforcing structure may be molded or sewn into the pouch material, or it may be attached using a suitable adhesive. A sewing ring 48, which may or may not include eyelets, is circumferentially formed around proximal opening 50. As with all of the embodiments shown, the pouch may taper inwardly towards distal opening 52 to form a funnel shape—or the pouch may have one of a variety of other shapes as discussed previously.
  • [0073]
    A third pouch 54 is shown in FIGS. 9A and 9B. Pouch 54 is similar to the pouch of FIG. 8 but further includes eyelets 56 in sewing ring 62, and a slightly cylindrical chute 58 adjacent to the distal opening 60. A fourth pouch 63, shown in FIG. 10, also includes a sewing ring 62 a, but differs in that its overall shape is shallower and less funnel-shaped.
  • [0074]
    As shown in FIG. 11, a pouch utilizing a sewing ring 65 (such as pouch 44 of FIG. 8, pouch 54 of FIG. 9A, or pouch 62 of FIG. 10) is preferably sewn or plicated into place or otherwise attached to tissue at the upper portion of the stomach S. This positioning is desirable so as to avoid suturing to the thinner esophageal tissue. Because the tissue of the stomach wall is thicker than the esophageal tissue, it provides a more desirable suturing surface. Alternatively, as shown in FIG. 12, a sewing ring 64, which may nitinol or polymeric, may be implanted separately from an associated pouch 66, and sewn-in or plicated to the stomach tissue before introduction of the pouch 66. Afterwards, the pouch 66 is introduced and attached to the ring 64 using sutures, clips or other attachment mechanisms.
  • [0075]
    To facilitate suturing of a pouch such as those described herein, it may be desirable to form pleats in the tissue at the gastro-esophageal junction region using sutures—in a manner similar to the pleating or “cinching” procedure performed as a treatment for gastro-intestinal reflux disease. Such tissue pleats are preferably formed in the stomach tissue below the z-line, and extend radially inwardly from the stomach walls by a small amount. These folds are more easily accessed by a suture needle or clips during attachment of the pouch and thus facilitate implantation of a pouch.
  • [0076]
    Two alternative mechanisms for forming plications in the stomach tissue are shown in FIGS. 13A, 13B and 14A, 14B. Referring to FIG. 13A, a first plication device includes a ring 68 having a central opening 67 and a plurality of spaced apart circumferential openings 69. Ring 68 is positionable within the proximal stomach as shown (using a sheath to facilitate insertion and placement if desired), such that its circumferential openings 69 are in contact with the stomach tissue surrounding the distal opening of the esophagus. A catheter 72 is extendable through central opening 67. Referring to FIG. 13B, a tissue puller 70 is longitudinally moveable through the catheter. Tissue puller 70 may take the form of an elongate wire having a helical tip—but may alternatively take any other form that will allow it to engage and pull tissue. A flexible locking ring 71 having a central opening shaped to engage tissue pulled through it (e.g., a star-shaped opening) is slidably disposed over the catheter 72 and puller 70.
  • [0077]
    To plicate tissue at the gastro-esophageal junction region using the device of FIGS. 13A, 13B, ring 68 is positioned against stomach tissue as shown in FIG. 13A. Catheter 72 is passed through central opening 67, and its distal end is steered to a position beneath one of the openings 69 in ring 68. Referring to FIG. 13B, the puller 70 is advanced through opening 69 until it engages the stomach tissue above the ring 68, and the engaged stomach tissue is then pulled through the opening 69 by retracting the puller 70 from the opening 69. A vacuum may be applied through the catheter 72 to assist in the pulling of tissue through the opening 69. Traction is maintained on the puller as locking ring 71 is advanced over the catheter 72 and puller 70, and further advanced over the cone C of tissue drawn through the opening 69—causing the cone of tissue to extend through the star-shaped opening in the locking ring and thereby forming a plication. The locking ring maintains the plication by locking against the tissue due to the points formed by the star-shaped opening. Additional barbs or hooks may be used to facilitate locking. This procedure may be used at some or all of the remaining openings 69 in the ring 68 to attach multiple locking rings 71 to stomach tissue around the perimeter of the esophagus—so as to form plications surrounding the esophagus. A pouch such as those described herein may then be sewn to the plications, or attached to the ring 68 using sutures, clips, adhesives or other suitable means.
  • [0078]
    Another plication device is shown in FIGS. 14A and 14B and includes an annular ring 73 having a plurality of circumferential openings 74. Ring 73 may be formed of an elastomeric material. A plurality of plicating clips 75 include jaw members that extend through adjacent openings 74 in the ring 73 as shown in FIG. 14B. Detachable actuators 77 are provided for opening and closing the jaw members of the plicating clips 75. To plicate tissue, ring 73 is positioned at the gastro-esophageal junction region, with its upper surface in contact with the tissue of the proximal stomach, surrounding the opening to the esophagus. The jaw members of the plicating clips are passed through the openings 74 and used to grasp tissue as shown in FIG. 14B—thereby forming plications in the tissue and holding the ring in place. The jaw members are closed, and locked in the closed position with the grasped tissue between them. The actuators 77 are detached from the clips, leaving the ring and clips in place so as to maintain the plications in the tissue. A satiation pouch may then be sutured to the plications in the tissue as described in connection with the various embodiments described herein, or attached to the ring 73 using sutures, clips, adhesives or other suitable attachment means.
  • [0079]
    FIGS. 15 and 16 show an embodiment of a pouch 78, which differs from prior embodiments in that it is formed as an inflatable cup having an air chamber 79, an inflation valve 82 near the proximal opening 80 and a detachable inflation tube 84. Sewing eyelets 86 surround the proximal opening. After the pouch 78 is deployed into the stomach from a deployment sheath 88 (see FIG. 16), it is inflated by injecting inflation medium (e.g., air or saline) from a syringe into inflation tube 84, and the valve 82 and tube 84 are disconnected from the pouch. When removal of the pouch is desired, the pouch 78 is pierced and deflated, and then pulled through the esophagus using an endoscopic grabber or similar tool.
  • [0080]
    Referring to FIGS. 17, 18A, and 18B, pouch 90 is formed of rings 92 formed of self-expanding material such as stainless steel, nitinol, or shape memory polymer, covered with a material such as Dacron® polyester, ePTFE fabric, or other polymer that will be durable when sutured to adjacent body tissue. Rings 92 are optionally linked together by ribs 94, which also may be formed of shape memory material.
  • [0081]
    The distal end of pouch 90 tapers into a chute 96. Chute 96 may be formed of a material similar to that of the pouch, or it may be formed of an elastic polymer, such as a low durometer polyethylene, silicone, elastic polyurethane materials etc. that permits radial expansion of the chute. Such expansion in response to a buildup of food material bearing against the chute may be desirable so as to prevent blockages in the chute. The chute 96 may be collapsible and thereby function as a check valve—preventing reflux of material from the stomach back into the pouch.
  • [0082]
    An annular sewing region 98 is positioned at the proximal end of the pouch. During implantation, sutures are connected to the sewing region and secured to adjacent tissue. To facilitate suturing of the pouch in place, it may be desirable to form tissue pleats at the gastro-esophageal junction region using sutures—in a manner similar to the pleating or “cinching” procedure performed as a treatment for gastro-intestinal reflux disease. Such tissue pleats extend radially inwardly from the stomach walls by a small amount, and thus can be easily accessed by a suture needle or clips during attachment of the pouch.
  • [0083]
    Pouch 90 may be provided with a delivery system that includes an elongate mandrel 100 extending through the pouch 90. A nose cone 102 is attached to the distal end of the mandrel, and includes a guidewire 104. Nose cone 102 is preferably flexible and free of sharp or blunt edges so as to prevent tissue trauma during implantation.
  • [0084]
    As shown in FIG. 18A, pouch 90 is folded and packaged within a positioning sheath 106 formed of a polymer such as a wire reinforced pebax, FEP, ePTFE, or other suitable material. The pouch is folded around the mandrel, and then the folded pouch and mandrel are positioned within the sheath. Various folding techniques may be employed for this purpose. The folded pouch may include bi-directional folds, or overlapping folds. Examples of such folds include propeller folds, rabbit ear folds, saddle folds or cloverleaf folds.
  • [0085]
    When the pouch is to be implanted, the sheath 106 (with the pouch inside) is introduced into the esophagus, with the guidewire 104 passing first through the esophagus and into the stomach. Once the sewing region 98 has reached the gastro-esophageal junction region, sheath 106 is withdrawn, causing the pouch to spring to the expanded position shown in FIG. 18B due to the self-expanding properties of rings 92. Slight tension is applied to the central mandrel as indicated by arrows in FIG. 18B, so as to cause the sewing region 98 to bear against the tissue encircling the distal opening of the esophagus—or against the pleats formed in the tissue as described above. With the sewing region 98 held against the tissue in this manner, sutures are passed through the sewing region and surrounding tissue so as to secure the pouch into the position shown in FIG. 17. Once the pouch has been sewn into place, the mandrel is withdrawn from the patient, leaving only the pouch in place. After suturing, the mandrel is pushed forward into the stomach where the stretchable nose cone collapses to a diameter smaller than the distal opening of the funnel, and is removed back out through the funnel and esophagus.
  • [0086]
    Referring to FIG. 19 an alternative pouch 108 may be formed of struts 110 or a mesh formed of nitinol, stainless steel, polymer (including shape memory polymer). A ring 112 is attached to the struts/mesh at the proximal end of the device, and also may be formed of nitinol, stainless steel, polymer (including shape memory polymer). The exterior or interior of the pouch covered with a material 114 that will prevent passage of food through the sides of the pouch. One example of such a material is a polyester material such Dacron® polyester sold by the DuPont Company.
  • [0087]
    FIGS. 20A and 20B show another example of a pouch 120. Pouch 120 is formed of a shape memory coil that has been heat set to a funnel shape. Dacron® polyester or other material 122 (FIG. 20B) may optionally cover the interior or exterior walls of the coil, although the coil may itself be sufficiently small as to prevent migration of food through the sidewalls of the coil. The material 122 may be pinched between proximal-most coil 124 and its adjacent coil as shown in FIG. 20B, so as to hold it in place.
  • [0088]
    As with the other pouches described herein, pouches 108, 120 of FIGS. 19-20B may be provided with a proximal-to-distal dimension that is fairly long (e.g., on the order of approximately 1.5-5.0 cm) and that thus gives the pouch a funnel shape as shown in FIGS. 19 and 20A. However, a variety of alternative shapes may be used for the pouch. For example, the pouch may have a much shorter proximal-to-distal dimension and thus take the shape of a shallow saucer with a small hole on its bottom surface
  • [0089]
    A stomach pouch may alternatively be one portion of a larger satiation device. For example, referring to FIG. 21A, the proximal portion of a pouch 125 may be connected to the proximal end of a larger cage structure 126. Cage 126 extends from the esophagus to the proximal portion of the antrum A. It may be a large stent-like structure preferably formed of self-expanding material, such as stainless steel or a shape memory material such as nitinol or polymer. Cage 126 functions primarily to distend the stomach to create a feeling of satiety. As shown, the pouch 125 is suspended into the interior of cage 126.
  • [0090]
    Additionally, the pouch 125 (as used with or without cage 126) may also be attached at its proximal end to an alignment extension 128. Referring to FIG. 21B, alignment extension 128 is a tubular stent portion that extends into the esophagus. In one embodiment, extension 128 may be approximately 5 cm in length. It functions primarily to keep the proximal opening of the pouch aligned with the esophagus—so that food passing through the esophagus passes easily into the pouch.
  • [0091]
    Yet another embodiment of a pouch device is shown in FIG. 22A. Pouch 130 is preferably formed of silicone material. The cross-sectional thickness of the pouch wall may differ in different regions of the pouch, so as to allow/limit expansion of the pouch in various locations. The silicone or other material may be coated with a lubricious, bio-compatible, chemically inert material, such as paraleyne, to reduce friction on the base material's surface which will help prevent sticking and food build up on the device.
  • [0092]
    Supporting members such as circumferential rings 132 and/or longitudinal ribs 134 (FIG. 22C) may be provided. If provided, such supporting members may be formed of thickened regions of silicone, or they may be separate plastic or nitinol components. As one example, illustrated in FIG. 22A, nitinol rings having an undulating pattern may provide structure to the pouch 130.
  • [0093]
    A neck 136 is positioned at the proximal end of the pouch 130 and is positionable within the gastro-esophageal junction region. During implantation the neck 136 is secured to the surrounding esophageal tissue and/or stomach tissue using sutures or clips. Suture holes, eyelets or grommets 138 in the neck 136 may be used to provide reinforced regions for anchoring the sutures. In addition, the reinforced locations and materials may be made of a suitably dense radio-opaque material, such as titanium or gold, to add in visualization of the device during or after the procedure. The reinforced locations and material may be of different colors to add in identification and orientation of sutures also. If desired, all or portion of the neck 340 may be formed of a woven material in lieu of silicone so as to provide a more durable sewing region.
  • [0094]
    A chute 140 is formed at the distal end of the pouch 130. Chute 140 may include supporting members such as ribs 134 (or rings such as rings 132) to provide rigidity to the chute. Alternatively, a collapsible chute such as chute 140 a shown in FIG. 22D may be utilized. The collapsible chute 140 a is provided without rib supports and thus is sufficiently flexible to collapse in response to reflux movement of food material from the stomach into the chute 140 a.
  • [0095]
    Fixation of the funnel device at the gastro-esophageal junction region may also be achieved by using bio-compatible adhesives, thermal fusion, or radio-frequency activated fixation.
  • [0096]
    The pouch 130, and each of the pouches described herein, may be delivered to the gastro-esophageal junction region using a delivery system such as the one described in connection with FIGS. 3-5, or using other types of delivery systems. An alternative delivery device 142 is shown in FIG. 23. Device 142 includes a plurality of grasper claws 144 extending from an elongate sleeve 146. Claws 144 include a handle 148 that is moveable in a distal direction to distally advance the claws 144 and to simultaneously spread the claws to the opened position shown in FIG. 24A. Movement of the handle 148 in a proximal direction retracts the claws 144 to the closed position shown in FIG. 24B, while simultaneously drawing the claws inside of the sleeve 146.
  • [0097]
    During use, the delivery device 142 is caused to engage the edge of the pouch (such as pouch 130) at the proximal or distal or end of the pouch. As the claws 144 are closed, they fold the end of the pouch with which they are engaged and draw the pouch towards (or, optionally, into) the sleeve 146. If the claws are used to engage the distal end of the pouch as shown in FIG. 25A, the pouch is preferably turned inside-out before hand, and then folded back over the claws 144 as shown in FIG. 25B to cover the claws. The claws 144, as covered by the pouch 130, are passed through the esophagus and into the stomach to position the pouch, preferably under endoscopic guidance. Once the pouch is within the stomach, the claws 144 are opened to release the pouch. The pouch is positioned in the gastro-esophageal junction region and sutures threaded through the eyelets of the pouch are sewn through neighboring tissue and knotted to secure the pouch in position.
  • [0098]
    Stomach pouches may alternatively be used as standalone devices without sutures—and may instead be held in place by the radial expansion forces of struts, mesh or coils forming part of the pouch structure. An example of such a pouch 150 is shown in FIG. 26. Pouch 150 includes a neck 152 formed of a flexible polymer, nylon, or Dacron® polyester. A plurality of rings 154 are disposed within this neck. Referring to FIGS. 27A and 27B, each ring 154 includes a break 156 which allows the ring to be radially compressed into the position shown in FIG. 27A—with the ends formed by the break slightly overlapping one another. Release of compression against the ring causes it to spring to the circular position shown in FIG. 27B.
  • [0099]
    A funnel portion 158 is provided at the distal end of the pouch. As with previous embodiments, when the pouch is implanted the neck 152 is disposed within the gastro-esophageal junction region (e.g., in the distal esophagus as shown) and the funnel portion 158 extends into the stomach.
  • [0100]
    Prior to implantation, the pouch 150 is preferably packaged within a sheath (not shown) with all of the rings in the compressed position shown in FIG. 27A. Once the neck is placed within the esophagus, the sheath is withdrawn, allowing the rings 154 to spring to the expanded position shown in FIG. 27B. The expanded rings bear against the wall of the esophagus or gastro-esophageal junction region, holding the neck 154 in contact with the wall. Secondary hooks 160 may be optionally provided on the exterior of the neck 154, such that radial expansion of the rings causes the hooks to engage the surrounding walls.
  • [0101]
    FIG. 28A shows an alternative pouch 162 that includes a neck 164 as the sewing region. During implantation, the neck 164 remains within the gastro-esophageal junction region and the distal end of the pouch 162 extends into the stomach. FIG. 28B illustrates that the neck may be secured to esophageal tissue (although as discussed previously it is believed that the tissue below the Z-line may be a more desirable attachment point). Biological adhesives are preferably used to attach the neck and adjacent esophageal tissue to hold the pouch in place. If sutures are used, the self-expanding rings 166 located in the neck may function as suture rings—around which the sutures may be secured. Chute 167 at the distal end may include a duck bill valve which functions as a check valve to control gastro-esophageal reflux.
  • [0102]
    Two embodiments of trans-esophageal satiation devices are shown in FIGS. 29 and 30. Referring to FIG. 29, pouch 168 is an elongate flexible device formed of a variably compliant material such as ePTFE, Dacron® polyester, or a polyurethane such as ChronoFlex® polyurethane. Pouch 168 includes a proximal portion 170 positionable within the esophagus and having a proximal opening 171. The pouch further includes an elongate mid-section, and a distal taper that extends into the stomach and that includes a distal opening 172. The flexible nature of the pouch allows for normal function of the esophageal sphincter.
  • [0103]
    The proximal portion 170 of the pouch (which sits in a proximal position relative to the esophageal sphincter) may include a self-expanding cylindrical stent structure that is formed of shape memory material such as nitinol, shape-memory polymer, or shape-memory alloy and that exerts radial pressure against the surrounding walls so as to hold itself in place within the esophagus. The stent may include barbs in its exterior surface to ensure that the pouch 168 does not move out of place. Alternatively, the proximal portion 172 may instead be attached to the surrounding walls using sutures or barbs. According to this alternative, the pouch may include a stent structure or be provided without.
  • [0104]
    The embodiment of FIG. 30 differs slightly from the embodiment of FIG. 29 in that it includes an optional tie-wrap restrictor 174 which regulates the rate at which food will move into the stomach from the pouch. The tie-wrap may be adjusted during implantation to select a flow rate appropriate for the patient. Moreover, an optional flapper valve 176 positionable in the vicinity of the esophageal sphincter aids in the prevention of gastro-esophageal reflux. A duckbill valve 178 at the distal opening 172 may also be provided for curtailing gastro-esophageal reflux.
  • [0105]
    Satiation pouches may be configured to allow the size of the pouch's distal opening to be increased or decreased. This enables a physician implanting such a device to set the distal opening to a size appropriate for a patient. In some cases, it will also allow the physician to make adjustments to the distal opening after it has been implanted. For example, if the patient is not losing weight at a desired rate, the physician might reduce the size of the distal opening—so that food will empty more slowly from the pouch into the stomach. The physician might alternatively increase the size of the distal opening if necessary if weight loss is occurring too rapidly.
  • [0106]
    Referring to FIG. 31, longitudinal cuts 180 may be formed in the distal end of the pouch to increase the effective size of the distal opening. These cuts may be made using endoscopic scissors after the pouch has been implanted, or they may be made prior to implantation. The device may be perforated or scored beforehand to facilitating cutting.
  • [0107]
    Referring to FIGS. 32A and 32B, a pouch 182 may alternatively be provided with a restrictor ring 184 surrounding the exterior of the pouch—near the distal opening. Ring 184 may be expanded by applying expansive radial forces from within the inner diameter of the ring (e.g., by positioning the jaws of a grasper within the funnel and then separating the jaws), or compressed using compressive forces applied to the exterior of the ring (e.g., by positioning the ring between the jaws and then closing them slightly). This expansion/compression may be performed prior to implantation, or after the pouch has been implanted.
  • [0108]
    FIG. 33 shows a third alternative embodiment of a pouch 186 having an adjustable distal opening. The FIG. 33 embodiment is similar to the FIG. 32A embodiment in that it relies upon expansion/contraction of a restrictor ring. Restrictor ring 188 is positioned inside the pouch near the distal opening. A pair of opposed slots 190 are formed in the interior surface of the ring 188. An endoscopically-controllable adjustment tool 192 includes a pair of extendable pins 194 at the distal end of an elongate shaft 196. Actuators 198 a,b on the proximal end of the adjustment tool 192 control extension of the pins between the retracted position (FIG. 34A) and the extended position (FIG. 34B). To adjust the diameter of the pouch 186, tool is inserted through the pouch with the pins 194 in the retracted position. Pins 194 are aligned with slots 190 in the ring 188 and are then extended using actuators 198 a. As they extend, the pins 194 slide into the slots 190. Next, the user rotates the tool 192 about its longitudinal axis, in either the clockwise or counter-clockwise direction. Rotation of the tool expands or contracts the ring, depending on the direction of rotation. After the ring size has been adjusted, the pins 194 are retracted using actuator 198 b, and the tool 192 is removed from the pouch 186.
  • [0109]
    Many techniques may be used to remove a satiation pouch from the stomach. One example is shown in FIGS. 36A-36D. First, if sutures or clips are used, endoscopic scissors 202 are passed through the mouth and esophagus and used to snip the sutures (FIG. 36A) or remove the clips. It may be desirable to engage the pouch 200 using, for example, a leash sewn through the pouch and extending out through the mouth, or an endoscopic grabber etc. to prevent the pouch from falling further into the stomach after it has been detached from the gastro-esophageal junction region.
  • [0110]
    Next, a sheath 204 is passed through the esophagus to the gastro-esophageal junction region. A retrieval device 206 having expandable claws 208 (that may be similar to those of the device of FIG. 23) is positioned with its claws 208 in a closed position, and is passed through the sheath. The claws 208 are opened, positioned around the proximal portion of the pouch 200 (FIG. 36B), and then closed to collapse the pouch between the claws (FIG. 36C). The claws 208 are then withdrawn through the sheath and out of the body to remove the pouch (FIG. 36D). To facilitate removal, a flexible hood 210 having a flared distal end may be extended through the sheath and positioned to extend from the distal end of the sheath (see FIG. 37) during pouch removal. The hood 210 helps guide the pouch into a compressed position as the pouch is drawn into the sheath 204. Once the pouch has been removed, the hood 210 is withdrawn from the body via the sheath 204, and then the sheath is withdrawn.
  • [0111]
    Referring to FIGS. 38A and 38B, a satiation pouch 212 may include a safety leash 216 that will retain the pouch 212 within the proximal region of the stomach in the event of failure of the primary mechanism (e.g., sutures, clips, adhesive, etch) for holding the pouch in position. Leash 216 extends from the pouch and is secured to the stomach wall at point 218. Leash 216 may be constructed using materials of the type used for the pouch, or using fiber reinforced ribbon of such materials. In the example shown in FIGS. 38A and 38B, the proximal portion of pouch 212 is secured in place using sutures at attachment points 214. If these suture connections should fail, the pouch will be retained by the leash, and will be prevented from migrating into the antrum or the pylorus region of the stomach, and will thus prevent an occlusive event.
  • [0112]
    Various embodiments of satiation device have been described herein. These embodiments are giving by way of example and are not intended to limit the scope of the present invention. It should be appreciated, moreover, that the various features of the embodiments that have been described may be combined in various ways to produce numerous additional embodiments. Moreover, while various materials, dimensions, shapes, implantation locations, etc. have been described for use with disclosed embodiments, others besides those disclosed may be utilized without exceeding the scope of the invention.
  • [0113]
    Any and all patents and applications referenced herein, including for purposes of priority, are hereby incorporated by reference.

Claims (17)

  1. 1. A gastroesophageal implant system, comprising:
    an implant;
    a plicator endoscopically engageable with stomach wall tissue to form a tissue plication; and
    an anchor adapted to be coupled to a stomach wall plication formed using the plicator, and to be coupled to the implant to retain the implant within the stomach.
  2. 2. The implant system of claim 1, wherein at least one of the implant and the anchor is a ring.
  3. 3. The system of claim 1, further including an endoscope extendable through a mouth of the patient and into the stomach, the endoscope operable to provide visualization of the implant and connector during implantation of the implant and the anchor.
  4. 4. The system according to claim 2, wherein the implant is a ring and further comprises a mesh wall attached to the ring.
  5. 5. The implant system of claim 1, wherein the implant, when coupled to the stomach wall plication, defines a restricted flow path from a first stomach region proximal to the implant to a second stomach region distal to the implant.
  6. 6. The implant system of claim 1, wherein the anchor is a clip.
  7. 7. The implant system of claim 1, wherein the plicator is a vacuum plicator.
  8. 8. A method for inducing weight loss in a patient, comprising the steps of:
    endoscopically forming a tissue plication within a stomach;
    coupling a first implant to the tissue plication;
    retaining the first implant within the stomach such that a first section of the stomach is proximal to the implant and a second section of the stomach is distal to the implant;
    wherein food ingested by the patient flows from the first section to the second section.
  9. 9. The method of claim 6, wherein the first implant is a flow-restrictive implant, and wherein food ingested by the patient flows through the flow-restrictive device from the first section to the second section.
  10. 10. The method of claim 8, further including after coupling the first implant, coupling a second implant to the first implant.
  11. 11. A system for limiting food intake by a patient, the system comprising:
    a flow-restrictive implant implantable within the stomach such that a first section of the stomach is proximal to the implant and a second section of the stomach is distal to the implant, the implant defining a flow path such that ingested food flows from the first section, through the flow path, and into the second section; and
    a connector adapted to couple to tissue within the stomach, the connector engageable with the implant to retain the implant within the stomach;
    wherein a portion of the implant is selectively moveable to alter the cross-sectional area of the flow path.
  12. 12. The system according to claim 11, wherein implant is a tubular device defined by a wall, wherein the wall is band expandable to increase the cross-sectional area and retractable to decrease the cross-section area.
  13. 13. A method of implanting a stomach implant, comprising the steps of:
    endoscopically coupling at least one elongate element to a stomach interior;
    threading a proximal portion of the elongate element through a stomach implant; and
    advancing the stomach implant over the elongate element and into contact with the stomach interior.
  14. 14. The method according to claim 13, wherein coupling the elongate element includes coupling the elongate element to a plication formed in stomach wall tissue.
  15. 15. The method according to claim 13, wherein the method further includes endoscopically coupling a plurality of elongate elements to plications formed in stomach wall tissue, threading each elongate element through a corresponding anchor point in the stomach implant.
  16. 16. The method according to claim 13, wherein threading of the proximal portion of the elongate element is performed outside the body.
  17. 17. The method according to claim 13, wherein the elongate element is a suture.
US11958587 2001-08-27 2007-12-18 Satiation devices and methods Abandoned US20080208356A1 (en)

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US10751751 US7981162B2 (en) 2001-08-27 2004-01-05 Satiation devices and methods
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US13182965 Active 2023-07-25 US8992457B2 (en) 2001-08-27 2011-07-14 Gastrointestinal implants
US14041757 Active US8845753B2 (en) 2001-08-27 2013-09-30 Satiation devices and methods
US14467434 Active US9138340B2 (en) 2001-08-27 2014-08-25 Gastro-esophageal implants
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US13182965 Active 2023-07-25 US8992457B2 (en) 2001-08-27 2011-07-14 Gastrointestinal implants
US14041757 Active US8845753B2 (en) 2001-08-27 2013-09-30 Satiation devices and methods
US14467434 Active US9138340B2 (en) 2001-08-27 2014-08-25 Gastro-esophageal implants
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Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030199991A1 (en) * 2001-08-27 2003-10-23 Stack Richard S. Satiation devices and methods
US20040117031A1 (en) * 2001-08-27 2004-06-17 Stack Richard S. Satiation devices and methods
US20080167629A1 (en) * 2006-09-25 2008-07-10 Valentx, Inc. Methods for toposcopic sleeve delivery
US7846138B2 (en) 2002-11-01 2010-12-07 Valentx, Inc. Cuff and sleeve system for gastrointestinal bypass
US7881797B2 (en) 2006-04-25 2011-02-01 Valentx, Inc. Methods and devices for gastrointestinal stimulation
US7934631B2 (en) 2008-11-10 2011-05-03 Barosense, Inc. Multi-fire stapling systems and methods for delivering arrays of staples
US7981162B2 (en) * 2001-08-27 2011-07-19 Barosense, Inc. Satiation devices and methods
US8012135B2 (en) 2002-11-01 2011-09-06 Valentx, Inc. Attachment cuff for gastrointestinal implant
US8029455B2 (en) 2003-01-16 2011-10-04 Barosense, Inc. Satiation pouches and methods of use
US20110270410A1 (en) * 2001-08-27 2011-11-03 Barosense, Inc. Satiation devices and methods
US20120041465A1 (en) * 2009-04-30 2012-02-16 Tidhar Shalon Devices and methods for treating gastrointestinal and metabolic disorders
US8182441B2 (en) 2007-06-08 2012-05-22 Valentx, Inc. Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices
US8211186B2 (en) 2009-04-03 2012-07-03 Metamodix, Inc. Modular gastrointestinal prostheses
US20120203061A1 (en) * 2009-10-26 2012-08-09 Allergan, Inc. Bariatric device and method for weight loss
US8241202B2 (en) 2004-04-26 2012-08-14 Barosense, Inc. Restrictive and/or obstructive implant for inducing weight loss
US8267888B2 (en) 2005-03-01 2012-09-18 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
US8282598B2 (en) 2009-07-10 2012-10-09 Metamodix, Inc. External anchoring configurations for modular gastrointestinal prostheses
US8337566B2 (en) 2002-04-08 2012-12-25 Barosense, Inc. Method and apparatus for modifying the exit orifice of a satiation pouch
US8469977B2 (en) 2005-10-03 2013-06-25 Barosense, Inc. Endoscopic plication device and method
US20130268089A1 (en) * 2010-08-10 2013-10-10 Ram Weiss Adapter for stomach devices
US8702641B2 (en) 2009-04-03 2014-04-22 Metamodix, Inc. Gastrointestinal prostheses having partial bypass configurations
US8784354B2 (en) 2001-08-27 2014-07-22 Boston Scientific Scimed, Inc. Positioning tools and methods for implanting medical devices
US8864008B2 (en) 2008-03-18 2014-10-21 Boston Scientific Scimed, Inc. Endoscopic stapling devices and methods
US8945167B2 (en) 2007-12-31 2015-02-03 Boston Scientific Scimed, Inc. Gastric space occupier systems and methods of use
US8956318B2 (en) 2012-05-31 2015-02-17 Valentx, Inc. Devices and methods for gastrointestinal bypass
US8961539B2 (en) 2009-05-04 2015-02-24 Boston Scientific Scimed, Inc. Endoscopic implant system and method
US9060844B2 (en) 2002-11-01 2015-06-23 Valentx, Inc. Apparatus and methods for treatment of morbid obesity
US9173760B2 (en) 2009-04-03 2015-11-03 Metamodix, Inc. Delivery devices and methods for gastrointestinal implants
US9180035B2 (en) 2003-10-10 2015-11-10 Boston Scientific Scimed, Inc. Devices and methods for retaining a gastro-esophageal implant
US9278019B2 (en) 2009-04-03 2016-03-08 Metamodix, Inc Anchors and methods for intestinal bypass sleeves
US9314361B2 (en) 2006-09-15 2016-04-19 Boston Scientific Scimed, Inc. System and method for anchoring stomach implant
US9445791B2 (en) 2003-10-10 2016-09-20 Boston Scientific Scimed, Inc. Systems and methods related to gastro-esophageal implants
US9451960B2 (en) 2012-05-31 2016-09-27 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US9622897B1 (en) 2016-03-03 2017-04-18 Metamodix, Inc. Pyloric anchors and methods for intestinal bypass sleeves
US9675489B2 (en) 2012-05-31 2017-06-13 Valentx, Inc. Devices and methods for gastrointestinal bypass
EP2841020B1 (en) * 2012-04-27 2017-07-26 Cook Medical Technologies LLC Anti-aspiration prosthesis
US9757264B2 (en) 2013-03-13 2017-09-12 Valentx, Inc. Devices and methods for gastrointestinal bypass

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7608114B2 (en) * 2002-12-02 2009-10-27 Gi Dynamics, Inc. Bariatric sleeve
CA2512203C (en) 2002-12-02 2012-10-23 Gi Dynamics, Inc. Bariatric sleeve
US20080190989A1 (en) * 2005-10-03 2008-08-14 Crews Samuel T Endoscopic plication device and method
US8038720B2 (en) * 2005-10-18 2011-10-18 Wallace Jeffrey M Methods and devices for intragastrointestinal prostheses
US7785366B2 (en) * 2005-10-26 2010-08-31 Maurer Christopher W Mitral spacer
FR2941046B1 (en) * 2009-01-15 2011-02-18 Ulis Device for detecting electromagnetic radiation
US9138308B2 (en) * 2010-02-03 2015-09-22 Apollo Endosurgery, Inc. Mucosal tissue adhesion via textured surface
WO2013044267A1 (en) * 2011-09-23 2013-03-28 Pulmonx, Inc. Implant loading device and system
US9149383B2 (en) * 2012-01-23 2015-10-06 Apollo Endosurgery, Inc. Endolumenal esophageal restriction device
US9456916B2 (en) 2013-03-12 2016-10-04 Medibotics Llc Device for selectively reducing absorption of unhealthy food
US9011365B2 (en) 2013-03-12 2015-04-21 Medibotics Llc Adjustable gastrointestinal bifurcation (AGB) for reduced absorption of unhealthy food
US9067070B2 (en) 2013-03-12 2015-06-30 Medibotics Llc Dysgeusia-inducing neurostimulation for modifying consumption of a selected nutrient type
US20150335453A1 (en) * 2014-05-21 2015-11-26 Endobar Solutions Llc Treatment for Obesity by Selectively Clipping the Gastric Fundus to Modify Blood Flow
US9579186B2 (en) * 2014-06-26 2017-02-28 Boston Scientific Scimed, Inc. Medical devices and methods to prevent bile reflux after bariatric procedures
EP3193780A1 (en) 2014-09-18 2017-07-26 Boston Scientific Scimed Inc. Device allowing pyloric sphincter to normally function for bariatric stents

Citations (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1408865A (en) * 1921-07-13 1922-03-07 Selden S Cowell Collapsible funnel
US4134405A (en) * 1977-01-10 1979-01-16 Smit Julie A Catheter and intestine tube and method of using the same
US4246893A (en) * 1978-07-05 1981-01-27 Daniel Berson Inflatable gastric device for treating obesity
US4315509A (en) * 1977-01-10 1982-02-16 Smit Julie A Insertion and removal catheters and intestinal tubes for restricting absorption
US4403604A (en) * 1982-05-13 1983-09-13 Wilkinson Lawrence H Gastric pouch
US4441215A (en) * 1980-11-17 1984-04-10 Kaster Robert L Vascular graft
US4501264A (en) * 1978-06-02 1985-02-26 Rockey Arthur G Medical sleeve
US4607618A (en) * 1983-02-23 1986-08-26 Angelchik Jean P Method for treatment of morbid obesity
US4648383A (en) * 1985-01-11 1987-03-10 Angelchik Jean P Peroral apparatus for morbid obesity treatment
US4694827A (en) * 1986-01-14 1987-09-22 Weiner Brian C Inflatable gastric device for treating obesity and method of using the same
US4723547A (en) * 1985-05-07 1988-02-09 C. R. Bard, Inc. Anti-obesity balloon placement system
US4747849A (en) * 1986-01-13 1988-05-31 Claude Galtier Oesophagus prosthesis
US4846836A (en) * 1988-10-03 1989-07-11 Reich Jonathan D Artificial lower gastrointestinal valve
US4899747A (en) * 1981-12-10 1990-02-13 Garren Lloyd R Method and appartus for treating obesity
US4997084A (en) * 1988-05-13 1991-03-05 Opielab, Inc. Packaging system for disposable endoscope sheaths
US5211658A (en) * 1991-11-05 1993-05-18 New England Deaconess Hospital Corporation Method and device for performing endovascular repair of aneurysms
US5234454A (en) * 1991-08-05 1993-08-10 Akron City Hospital Percutaneous intragastric balloon catheter and method for controlling body weight therewith
US5246456A (en) * 1992-06-08 1993-09-21 Wilkinson Lawrence H Fenestrated gastric pouch
US5290217A (en) * 1991-10-10 1994-03-01 Earl K. Sipes Method and apparatus for hernia repair
US5306300A (en) * 1992-09-22 1994-04-26 Berry H Lee Tubular digestive screen
US5314473A (en) * 1989-07-20 1994-05-24 Godin Norman J Prosthesis for preventing gastric reflux into the esophagus
US5327914A (en) * 1992-09-02 1994-07-12 Shlain Leonard M Method and devices for use in surgical gastroplastic procedure
US5345949A (en) * 1992-09-02 1994-09-13 Shlain Leonard M Methods for use in surgical gastroplastic procedure
US5401241A (en) * 1992-05-07 1995-03-28 Inamed Development Co. Duodenal intubation catheter
US5405377A (en) * 1992-02-21 1995-04-11 Endotech Ltd. Intraluminal stent
US5514176A (en) * 1995-01-20 1996-05-07 Vance Products Inc. Pull apart coil stent
US5593434A (en) * 1992-01-31 1997-01-14 Advanced Cardiovascular Systems, Inc. Stent capable of attachment within a body lumen
US5609624A (en) * 1993-10-08 1997-03-11 Impra, Inc. Reinforced vascular graft and method of making same
US5628786A (en) * 1995-05-12 1997-05-13 Impra, Inc. Radially expandable vascular graft with resistance to longitudinal compression and method of making same
US5653743A (en) * 1994-09-09 1997-08-05 Martin; Eric C. Hypogastric artery bifurcation graft and method of implantation
US5662713A (en) * 1991-10-09 1997-09-02 Boston Scientific Corporation Medical stents for body lumens exhibiting peristaltic motion
US5709657A (en) * 1989-06-28 1998-01-20 Zimmon Science Corporation Methods for placement of balloon tamponade devices
US5720776A (en) * 1991-10-25 1998-02-24 Cook Incorporated Barb and expandable transluminal graft prosthesis for repair of aneurysm
US5720657A (en) * 1995-11-10 1998-02-24 Denso Corporation Air passage switching device and air conditioning apparatus using the same
US5749918A (en) * 1995-07-20 1998-05-12 Endotex Interventional Systems, Inc. Intraluminal graft and method for inserting the same
US5771903A (en) * 1995-09-22 1998-06-30 Kirk Promotions Limited Surgical method for reducing the food intake of a patient
US5855601A (en) * 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same
US5861036A (en) * 1995-03-28 1999-01-19 Biomedix S.A. Switzerland Medical prosthesis for preventing gastric reflux in the esophagus
US5868141A (en) * 1997-05-14 1999-02-09 Ellias; Yakub A. Endoscopic stomach insert for treating obesity and method for use
US5887594A (en) * 1997-09-22 1999-03-30 Beth Israel Deaconess Medical Center Inc. Methods and devices for gastroesophageal reflux reduction
US5922019A (en) * 1995-11-27 1999-07-13 Schneider (Europe) A.G. Conical stent
US6016848A (en) * 1996-07-16 2000-01-25 W. L. Gore & Associates, Inc. Fluoropolymer tubes and methods of making same
US6102922A (en) * 1995-09-22 2000-08-15 Kirk Promotions Limited Surgical method and device for reducing the food intake of patient
US6113609A (en) * 1998-05-26 2000-09-05 Scimed Life Systems, Inc. Implantable tissue fastener and system for treating gastroesophageal reflux disease
US6120534A (en) * 1997-10-29 2000-09-19 Ruiz; Carlos E. Endoluminal prosthesis having adjustable constriction
US6254642B1 (en) * 1997-12-09 2001-07-03 Thomas V. Taylor Perorally insertable gastroesophageal anti-reflux valve prosthesis and tool for implantation thereof
US6258120B1 (en) * 1997-12-23 2001-07-10 Embol-X, Inc. Implantable cerebral protection device and methods of use
US6264700B1 (en) * 1998-08-27 2001-07-24 Endonetics, Inc. Prosthetic gastroesophageal valve
US20010011543A1 (en) * 1999-08-12 2001-08-09 Peter Forsell Controlled food flow in a patient
US6287334B1 (en) * 1996-12-18 2001-09-11 Venpro Corporation Device for regulating the flow of blood through the blood system
US20010021796A1 (en) * 1998-12-11 2001-09-13 Enteric Medical Technologies, Inc. Method for treating tissue and apparatus for use therewith
US20020022851A1 (en) * 2000-08-17 2002-02-21 Johns Hopkins University Gastric reduction endoscopy
US20020055757A1 (en) * 2000-11-03 2002-05-09 Torre Roger De La Method and device for use in minimally invasive placement of intragastric devices
US20020099439A1 (en) * 2000-09-29 2002-07-25 Schwartz Robert S. Venous valvuloplasty device and method
US6425916B1 (en) * 1999-02-10 2002-07-30 Michi E. Garrison Methods and devices for implanting cardiac valves
US6503264B1 (en) * 2000-03-03 2003-01-07 Bioenterics Corporation Endoscopic device for removing an intragastric balloon
US20030009236A1 (en) * 1999-12-13 2003-01-09 Norman Godin Prosthesis for controlling the direction of flow in a duct of a living organism
US6540789B1 (en) * 2000-06-15 2003-04-01 Scimed Life Systems, Inc. Method for treating morbid obesity
US6547801B1 (en) * 1998-09-14 2003-04-15 Sofradim Production Gastric constriction device
US6558400B2 (en) * 2001-05-30 2003-05-06 Satiety, Inc. Obesity treatment tools and methods
US6572627B2 (en) * 2001-01-08 2003-06-03 Shlomo Gabbay System to inhibit and/or control expansion of anatomical features
US6596023B1 (en) * 1996-05-24 2003-07-22 Meadox Medicals, Inc. Shaped woven tubular soft-tissue prostheses and method of manufacturing the same
US6675809B2 (en) * 2001-08-27 2004-01-13 Richard S. Stack Satiation devices and methods
US20040092892A1 (en) * 2002-11-01 2004-05-13 Jonathan Kagan Apparatus and methods for treatment of morbid obesity
US6740121B2 (en) * 2001-11-09 2004-05-25 Boston Scientific Corporation Intragastric stent for duodenum bypass
US20040107004A1 (en) * 2002-12-02 2004-06-03 Seedling Enterprises, Llc Bariatric sleeve
US20040117031A1 (en) * 2001-08-27 2004-06-17 Stack Richard S. Satiation devices and methods
US20040138761A1 (en) * 2001-08-27 2004-07-15 Stack Richard S. Satiation devices and methods
US20040143342A1 (en) * 2003-01-16 2004-07-22 Stack Richard S. Satiation pouches and methods of use
US20040148034A1 (en) * 2002-11-01 2004-07-29 Jonathan Kagan Apparatus and methods for treatment of morbid obesity
US20050096673A1 (en) * 2003-10-10 2005-05-05 Stack Richard S. Devices and methods for retaining a gastro-esophageal implant
US20050149114A1 (en) * 2002-08-29 2005-07-07 Cartledge Richard G. Apparatus for implanting surgical devices for controlling the internal circumference of an anatomic orifice or lumen
US7011094B2 (en) * 2001-03-02 2006-03-14 Emphasys Medical, Inc. Bronchial flow control devices and methods of use
US7097665B2 (en) * 2003-01-16 2006-08-29 Synecor, Llc Positioning tools and methods for implanting medical devices
US20070010864A1 (en) * 2002-11-01 2007-01-11 Mitchell Dann Gastrointestinal implant system
US7211114B2 (en) * 2002-08-26 2007-05-01 The Trustees Of Columbia University In The City Of New York Endoscopic gastric bypass
US7220237B2 (en) * 2002-10-23 2007-05-22 Satiety, Inc. Method and device for use in endoscopic organ procedures
US7220285B2 (en) * 2001-02-02 2007-05-22 L'oreal S.A. Pulverulent composition for bleaching human keratin fibers
US7229428B2 (en) * 2002-10-23 2007-06-12 Satiety, Inc. Method and device for use in endoscopic organ procedures
US20070198074A1 (en) * 2002-11-01 2007-08-23 Mitchell Dann Devices and methods for endolumenal gastrointestinal bypass
US7315509B2 (en) * 2003-01-10 2008-01-01 Samsung Electronics Co., Ltd. Method for recovering from a received data error in a mobile communication system providing a multimedia broadcast/multicast service
US7335210B2 (en) * 2002-04-03 2008-02-26 Julie Ann Smit Endoscope and tools for applying sealants and adhesives and intestinal lining for reducing food absorption
US20090018558A1 (en) * 2006-10-04 2009-01-15 Michael Laufer Methods of organ reconfiguration
US7575586B2 (en) * 1998-01-30 2009-08-18 St. Jude Medical Atg, Inc. Medical graft connector or plug structures, and methods of making and installing same

Family Cites Families (247)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3663965A (en) 1970-06-08 1972-05-23 Henry L Lee Jr Bacteria-resistant percutaneous conduit device
US4207890A (en) 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
US4331277A (en) 1980-05-23 1982-05-25 United States Surgical Corporation Self-contained gas powered surgical stapler
US4467804A (en) 1980-10-20 1984-08-28 American Cyanamid Company Anastomotic device
US4417360A (en) 1981-07-31 1983-11-29 Manoutchehr Moasser Nontraumatic prosthetic valve with magnetic closure
US4416267A (en) 1981-12-10 1983-11-22 Garren Lloyd R Method and apparatus for treating obesity
US4485805A (en) 1982-08-24 1984-12-04 Gunther Pacific Limited Of Hong Kong Weight loss device and method
US4488523A (en) 1982-09-24 1984-12-18 United States Surgical Corporation Flexible, hydraulically actuated device for applying surgical fasteners
US4612933A (en) 1984-03-30 1986-09-23 Senmed, Inc. Multiple-load cartridge assembly for a linear surgical stapling instrument
US4617932A (en) 1984-04-25 1986-10-21 Elliot Kornberg Device and method for performing an intraluminal abdominal aortic aneurysm repair
GB8422863D0 (en) 1984-09-11 1984-10-17 Univ London Sewing machine
GB2189150B (en) 1986-04-21 1990-02-14 Medinvent Sa Prosthesis and process for its manufacture
US4848367A (en) 1987-02-11 1989-07-18 Odis L. Avant Method of effecting dorsal vein ligation
US5542949A (en) 1987-05-14 1996-08-06 Yoon; Inbae Multifunctional clip applier instrument
DE8708978U1 (en) 1987-06-29 1987-11-12 Gip Gastrointestinale Produkte Vertriebs Gmbh, 8221 Grabenstaett, De
US5084061A (en) 1987-09-25 1992-01-28 Gau Fred C Intragastric balloon with improved valve locating means
US4925446A (en) 1988-07-06 1990-05-15 Transpharm Group Inc. Removable inflatable intragastrointestinal device for delivering beneficial agents
US4946440A (en) 1988-10-05 1990-08-07 Hall John E Evertible membrane catheter and method of use
US4969896A (en) 1989-02-01 1990-11-13 Interpore International Vascular graft prosthesis and method of making the same
US5431673A (en) 1989-02-17 1995-07-11 American Biomed, Inc. Distal atherectomy catheter
DE69004409T2 (en) 1989-07-20 1994-05-11 Norman Godin Prosthesis for preventing a gastric flow back into the esophagus.
US5163952A (en) 1990-09-14 1992-11-17 Michael Froix Expandable polymeric stent with memory and delivery apparatus and method
US5006106A (en) 1990-10-09 1991-04-09 Angelchik Jean P Apparatus and method for laparoscopic implantation of anti-reflux prosthesis
US5088979A (en) 1990-10-11 1992-02-18 Wilson-Cook Medical Inc. Method for esophageal invagination and devices useful therein
US5478003A (en) 1991-10-18 1995-12-26 United States Surgical Corporation Surgical apparatus
US5259399A (en) 1992-03-02 1993-11-09 Alan Brown Device and method of causing weight loss using removable variable volume intragastric bladder
US5355897A (en) 1992-04-16 1994-10-18 Ethicon, Inc. Method of performing a pyloroplasty/pylorectomy using a stapler having a shield
US5263629A (en) 1992-06-29 1993-11-23 Ethicon, Inc. Method and apparatus for achieving hemostasis along a staple line
US5322501A (en) * 1992-10-02 1994-06-21 Mahmud Durrani Ayaz Continent urethral stent for treating and preventing urethral stricture after surgery
US5601224A (en) 1992-10-09 1997-02-11 Ethicon, Inc. Surgical instrument
DE4236210C1 (en) 1992-10-27 1994-04-14 Olympus Optical Europ A tubular implant for use in percutaneous food intake
US5403326A (en) 1993-02-01 1995-04-04 The Regents Of The University Of California Method for performing a gastric wrap of the esophagus for use in the treatment of esophageal reflux
US5480423A (en) 1993-05-20 1996-01-02 Boston Scientific Corporation Prosthesis delivery
US5486187A (en) 1994-01-04 1996-01-23 Schenck; Robert R. Anastomosis device and method
US5597107A (en) 1994-02-03 1997-01-28 Ethicon Endo-Surgery, Inc. Surgical stapler instrument
GB9405790D0 (en) 1994-03-23 1994-05-11 Univ London Sewing device
CA2145723A1 (en) 1994-03-30 1995-10-01 Steven W. Hamblin Surgical stapling instrument with remotely articulated stapling head assembly on rotatable support shaft
US5529235A (en) 1994-04-28 1996-06-25 Ethicon Endo-Surgery, Inc. Identification device for surgical instrument
US5470007A (en) 1994-05-02 1995-11-28 Minnesota Mining And Manufacturing Company Laparoscopic stapler with overload sensor and interlock
US5489058A (en) 1994-05-02 1996-02-06 Minnesota Mining And Manufacturing Company Surgical stapler with mechanisms for reducing the firing force
US5571116A (en) 1994-10-02 1996-11-05 United States Surgical Corporation Non-invasive treatment of gastroesophageal reflux disease
US5484694A (en) * 1994-11-21 1996-01-16 Eastman Kodak Company Imaging element comprising an electrically-conductive layer containing antimony-doped tin oxide particles
US5868760A (en) 1994-12-07 1999-02-09 Mcguckin, Jr.; James F. Method and apparatus for endolumenally resectioning tissue
US5632432A (en) 1994-12-19 1997-05-27 Ethicon Endo-Surgery, Inc. Surgical instrument
WO1996025897A3 (en) 1995-02-22 1996-11-21 Menlo Care Inc Covered expanding mesh stent
US5706998A (en) 1995-07-17 1998-01-13 United States Surgical Corporation Surgical stapler with alignment pin locking mechanism
US5839639A (en) 1995-08-17 1998-11-24 Lasersurge, Inc. Collapsible anvil assembly and applicator instrument
US5785684A (en) 1996-02-06 1998-07-28 Zimmon Science Corporation Apparatus and method for the deployment of an esophagastric balloon tamponade device
US5762255A (en) 1996-02-20 1998-06-09 Richard-Allan Medical Industries, Inc. Surgical instrument with improvement safety lockout mechanisms
US6119913A (en) 1996-06-14 2000-09-19 Boston Scientific Corporation Endoscopic stapler
US5856445A (en) 1996-10-18 1999-01-05 Washington University Serine substituted mutants of BCL-XL /BCL-2 associated cell death regulator
US5846260A (en) 1997-05-08 1998-12-08 Embol-X, Inc. Cannula with a modular filter for filtering embolic material
US5976158A (en) 1997-06-02 1999-11-02 Boston Scientific Corporation Method of using a textured ligating band
US5848964A (en) 1997-06-06 1998-12-15 Samuels; Shaun Lawrence Wilkie Temporary inflatable filter device and method of use
US6245088B1 (en) 1997-07-07 2001-06-12 Samuel R. Lowery Retrievable umbrella sieve and method of use
DE69732229D1 (en) 1997-07-17 2005-02-17 Schneider Europ Gmbh Buelach Stent and manufacturing method thereof
DE19731834A1 (en) 1997-07-24 1999-06-17 Ernst Peter Prof Dr M Strecker implanter
US5957920A (en) 1997-08-28 1999-09-28 Isothermix, Inc. Medical instruments and techniques for treatment of urinary incontinence
US5820584A (en) 1997-08-28 1998-10-13 Crabb; Jerry A. Duodenal insert and method of use
FR2768324B1 (en) 1997-09-12 1999-12-10 Jacques Seguin A surgical instrument for percutaneously, fixing one to the other two zones of soft tissue, usually spaced apart
US6086600A (en) 1997-11-03 2000-07-11 Symbiosis Corporation Flexible endoscopic surgical instrument for invagination and fundoplication
US5993473A (en) 1997-11-19 1999-11-30 Chan; Yung C. Expandable body device for the gastric cavity and method
US5910144A (en) 1998-01-09 1999-06-08 Endovascular Technologies, Inc. Prosthesis gripping system and method
US5938697A (en) 1998-03-04 1999-08-17 Scimed Life Systems, Inc. Stent having variable properties
US5947983A (en) 1998-03-16 1999-09-07 Boston Scientific Corporation Tissue cutting and stitching device and method
US6740098B2 (en) 1998-05-11 2004-05-25 Surgical Connections, Inc. Surgical stabilizer devices and methods
US6478210B2 (en) 2000-10-25 2002-11-12 Scimed Life Systems, Inc. Method and device for full thickness resectioning of an organ
US6601749B2 (en) 1998-06-19 2003-08-05 Scimed Life Systems, Inc. Multi fire full thickness resectioning device
US6126058A (en) 1998-06-19 2000-10-03 Scimed Life Systems, Inc. Method and device for full thickness resectioning of an organ
US6206930B1 (en) 1998-08-10 2001-03-27 Charlotte-Mecklenburg Hospital Authority Absorbable tissue expander
US6460543B1 (en) 1998-08-13 2002-10-08 Obtech Medical Ag Non-injection port food intake restriction device
WO2000012027A1 (en) 1998-08-27 2000-03-09 Endonetics, Inc. Lower esophageal bulking device
US7118600B2 (en) * 1998-08-31 2006-10-10 Wilson-Cook Medical, Inc. Prosthesis having a sleeve valve
US6746489B2 (en) * 1998-08-31 2004-06-08 Wilson-Cook Medical Incorporated Prosthesis having a sleeve valve
JP2002531169A (en) 1998-08-31 2002-09-24 ウイルソンークック メディカル インク. Anti-reflux esophageal prosthesis
US6159146A (en) 1999-03-12 2000-12-12 El Gazayerli; Mohamed Mounir Method and apparatus for minimally-invasive fundoplication
US6098629A (en) 1999-04-07 2000-08-08 Endonetics, Inc. Submucosal esophageal bulking device
EP1180004A1 (en) 1999-05-18 2002-02-20 Silhouette Medical Inc. Surgical weight control device
US6494888B1 (en) 1999-06-22 2002-12-17 Ndo Surgical, Inc. Tissue reconfiguration
US6663639B1 (en) 1999-06-22 2003-12-16 Ndo Surgical, Inc. Methods and devices for tissue reconfiguration
US6506196B1 (en) 1999-06-22 2003-01-14 Ndo Surgical, Inc. Device and method for correction of a painful body defect
WO2003099137A2 (en) 1999-06-22 2003-12-04 Ndo Surgical, Inc. Method and devices for tissue reconfiguration
US6835200B2 (en) 1999-06-22 2004-12-28 Ndo Surgical. Inc. Method and devices for tissue reconfiguration
US6821285B2 (en) 1999-06-22 2004-11-23 Ndo Surgical, Inc. Tissue reconfiguration
US8287554B2 (en) 1999-06-22 2012-10-16 Ethicon Endo-Surgery, Inc. Method and devices for tissue reconfiguration
US7160312B2 (en) 1999-06-25 2007-01-09 Usgi Medical, Inc. Implantable artificial partition and methods of use
US7744613B2 (en) 1999-06-25 2010-06-29 Usgi Medical, Inc. Apparatus and methods for forming and securing gastrointestinal tissue folds
US20040249367A1 (en) 2003-01-15 2004-12-09 Usgi Medical Corp. Endoluminal tool deployment system
US8574243B2 (en) 1999-06-25 2013-11-05 Usgi Medical, Inc. Apparatus and methods for forming and securing gastrointestinal tissue folds
US7955340B2 (en) 1999-06-25 2011-06-07 Usgi Medical, Inc. Apparatus and methods for forming and securing gastrointestinal tissue folds
US6245087B1 (en) 1999-08-03 2001-06-12 Embol-X, Inc. Variable expansion frame system for deploying medical devices and methods of use
CN1222249C (en) 2000-02-10 2005-10-12 奥比特克医疗公司 Controlled stomach-ache and reflux disease treatment apparatus
US6358197B1 (en) 1999-08-13 2002-03-19 Enteric Medical Technologies, Inc. Apparatus for forming implants in gastrointestinal tract and kit for use therewith
US7662161B2 (en) 1999-09-13 2010-02-16 Rex Medical, L.P Vascular hole closure device
FR2799118B1 (en) 1999-10-01 2002-07-12 Medical Innovation Dev adjustable gastric implant
US6428548B1 (en) 1999-11-18 2002-08-06 Russell F. Durgin Apparatus and method for compressing body tissue
JP2003526410A (en) 1999-12-07 2003-09-09 トランスニューロニックス インコーポレイテッド Band of removable stomach
US6547776B1 (en) 2000-01-03 2003-04-15 Curon Medical, Inc. Systems and methods for treating tissue in the crura
CA2400196A1 (en) 2000-02-15 2001-08-23 Eva Corporation Delivery catheter assembly and method of securing a surgical component to a vessel during a surgical procedure
US6454785B2 (en) 2000-02-24 2002-09-24 DE HOYOS GARZA ANDRéS Percutaneous intragastric balloon catheter for the treatment of obesity
US7399304B2 (en) 2000-03-03 2008-07-15 C.R. Bard, Inc. Endoscopic tissue apposition device with multiple suction ports
WO2001089393A1 (en) 2000-05-19 2001-11-29 C.R. Bard, Inc. Tissue capturing and suturing device and method
FR2805986B1 (en) 2000-03-13 2002-10-11 Districlass Madical intragastric device has variable volume
JP4939717B2 (en) 2000-05-02 2012-05-30 ウィルソン−クック メディカル インコーポレイテッド Catheter o with a Mekurikaeshi sleeve. t. l for the introduction device
US6592596B1 (en) 2000-05-10 2003-07-15 Scimed Life Systems, Inc. Devices and related methods for securing a tissue fold
JP4368498B2 (en) * 2000-05-16 2009-11-18 Necエレクトロニクス株式会社 Semiconductor device, a semiconductor wafer and a process for their preparation
US6544271B1 (en) 2000-07-18 2003-04-08 Scimed Life Systems, Inc. Device for full-thickness resectioning of an organ
US20020082621A1 (en) 2000-09-22 2002-06-27 Schurr Marc O. Methods and devices for folding and securing tissue
US6736828B1 (en) 2000-09-29 2004-05-18 Scimed Life Systems, Inc. Method for performing endoluminal fundoplication and apparatus for use in the method
US7232445B2 (en) 2000-12-06 2007-06-19 Id, Llc Apparatus for the endoluminal treatment of gastroesophageal reflux disease (GERD)
US7229453B2 (en) 2001-01-23 2007-06-12 Ams Research Corporation Pelvic floor implant system and method of assembly
EP1359851B1 (en) 2001-01-31 2010-09-22 Rex Medical, Inc. Apparatus for stapling and resectioning gastro-edophageal tissue
WO2002071951A1 (en) 2001-03-09 2002-09-19 Garza Alvarez Jose Rafael Intragastric balloon assembly
US7020531B1 (en) 2001-05-01 2006-03-28 Intrapace, Inc. Gastric device and suction assisted method for implanting a device on a stomach wall
US6535764B2 (en) 2001-05-01 2003-03-18 Intrapace, Inc. Gastric treatment and diagnosis device and method
US20050143760A1 (en) 2001-05-01 2005-06-30 Imran Mir A. Endoscopic gastric constriction device
US6592597B2 (en) 2001-05-07 2003-07-15 Ethicon Endo-Surgery, Inc. Adhesive for attaching buttress material to a surgical fastening device
DE60229263D1 (en) 2001-05-17 2008-11-20 Wilson Cook Medical Inc Intragastric device for treating obesity
US6916332B2 (en) 2001-05-23 2005-07-12 Scimed Life Systems, Inc. Endoluminal fundoplication device and related method for installing tissue fastener
US7083629B2 (en) 2001-05-30 2006-08-01 Satiety, Inc. Overtube apparatus for insertion into a body
US20020188354A1 (en) 2001-06-12 2002-12-12 Peghini Paolo Lino Device to treat obesity by obstructing gastric outlet
US6627206B2 (en) 2001-07-25 2003-09-30 Greg A. Lloyd Method and apparatus for treating obesity and for delivering time-released medicaments
US6632227B2 (en) 2001-08-24 2003-10-14 Scimed Life Systems, Inc. Endoscopic resection devices
JP4426852B2 (en) 2002-04-08 2010-03-03 シネコー・エルエルシー Saturated devices and methods
CN101810521B (en) * 2001-08-27 2015-05-13 辛尼科有限责任公司 Satiation devices and methods
US7146984B2 (en) 2002-04-08 2006-12-12 Synecor, Llc Method and apparatus for modifying the exit orifice of a satiation pouch
US7334717B2 (en) 2001-10-05 2008-02-26 Tyco Healthcare Group Lp Surgical fastener applying apparatus
US6755869B2 (en) 2001-11-09 2004-06-29 Boston Scientific Corporation Intragastric prosthesis for the treatment of morbid obesity
US6790237B2 (en) 2001-10-09 2004-09-14 Scimed Life Systems, Inc. Medical stent with a valve and related methods of manufacturing
US6675776B2 (en) * 2001-12-14 2004-01-13 Caterpillar Inc Electro-hydraulic actuator for a hydraulic pump
US7261722B2 (en) 2001-12-20 2007-08-28 Rex Medical, L.P. Apparatus and method for treating gastroesophageal reflux disease
JP4230915B2 (en) 2001-12-21 2009-02-25 シムチャ ミロ Transplant system for the annuloplasty ring
US6733512B2 (en) 2002-03-07 2004-05-11 Mcghan Jim J. Self-deflating intragastric balloon
US7128748B2 (en) 2002-03-26 2006-10-31 Synovis Life Technologies, Inc. Circular stapler buttress combination
US6752828B2 (en) 2002-04-03 2004-06-22 Scimed Life Systems, Inc. Artificial valve
WO2003090631A1 (en) 2002-04-24 2003-11-06 Surgical Connections, Inc. Resection and anastomosis devices and methods
US8241308B2 (en) 2002-04-24 2012-08-14 Boston Scientific Scimed, Inc. Tissue fastening devices and processes that promote tissue adhesion
KR20050010765A (en) 2002-05-07 2005-01-28 에이엠에스 리써치 코오포레이션 Urethral prosthesis with tensioning member
JP2005524485A (en) * 2002-05-09 2005-08-18 ディー.イーガン トマス Bypass prosthesis method of stomach
CA2484838C (en) 2002-05-09 2012-08-28 Applied Medical Resources Corporation Balloon system and methods for treating obesity
US6790214B2 (en) 2002-05-17 2004-09-14 Esophyx, Inc. Transoral endoscopic gastroesophageal flap valve restoration device, assembly, system and method
ES2383252T3 (en) 2002-06-17 2012-06-19 Tyco Healthcare Group Lp annular support structures
US6773440B2 (en) 2002-07-02 2004-08-10 Satiety, Inc. Method and device for use in tissue approximation and fixation
US20040098043A1 (en) 2002-07-09 2004-05-20 Trout Hugh H. Delivery apparatus for use during a surgical procedure and method of using the same
US20040133219A1 (en) 2002-07-29 2004-07-08 Peter Forsell Multi-material constriction device for forming stoma opening
US6746460B2 (en) 2002-08-07 2004-06-08 Satiety, Inc. Intra-gastric fastening devices
US20040044364A1 (en) 2002-08-29 2004-03-04 Devries Robert Tissue fasteners and related deployment systems and methods
US7214233B2 (en) 2002-08-30 2007-05-08 Satiety, Inc. Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
US7033384B2 (en) 2002-08-30 2006-04-25 Satiety, Inc. Stented anchoring of gastric space-occupying devices
US6981978B2 (en) 2002-08-30 2006-01-03 Satiety, Inc. Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
KR100442330B1 (en) * 2002-09-03 2004-07-30 주식회사 엠아이텍 Stent and manufacturing method the same
ES2379348T3 (en) 2002-10-04 2012-04-25 Tyco Healthcare Group Lp Motorized surgical stapling device pneumatically
US8105345B2 (en) 2002-10-04 2012-01-31 Medtronic, Inc. Anastomosis apparatus and methods
US7794447B2 (en) 2002-11-01 2010-09-14 Valentx, Inc. Gastrointestinal sleeve device and methods for treatment of morbid obesity
US20090149871A9 (en) 2002-11-01 2009-06-11 Jonathan Kagan Devices and methods for treating morbid obesity
WO2004041133A1 (en) 2002-11-01 2004-05-21 Valentx, Inc. Apparatus and methods for treatment of morbid obesity
CA2512203C (en) 2002-12-02 2012-10-23 Gi Dynamics, Inc. Bariatric sleeve
US7695446B2 (en) 2002-12-02 2010-04-13 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
US7608114B2 (en) 2002-12-02 2009-10-27 Gi Dynamics, Inc. Bariatric sleeve
US7678068B2 (en) 2002-12-02 2010-03-16 Gi Dynamics, Inc. Atraumatic delivery devices
US6960233B1 (en) 2002-12-10 2005-11-01 Torax Medical, Inc. Methods and apparatus for improving the function of biological passages
US7291160B2 (en) 2003-03-17 2007-11-06 Delegge Rebecca Intragastric catheter
US6981980B2 (en) 2003-03-19 2006-01-03 Phagia Technology Self-inflating intragastric volume-occupying device
US20060058829A1 (en) 2003-03-19 2006-03-16 Sampson Douglas C Intragastric volume-occupying device
US20040220682A1 (en) 2003-03-28 2004-11-04 Gi Dynamics, Inc. Anti-obesity devices
US7175638B2 (en) 2003-04-16 2007-02-13 Satiety, Inc. Method and devices for modifying the function of a body organ
JP4940388B2 (en) 2003-04-24 2012-05-30 クック メディカル テクノロジーズ エルエルシーCook Medical Technologies Llc Prosthetic valve proteinase with improved hydrodynamic characteristics - Ze
US7731757B2 (en) 2003-06-01 2010-06-08 Reflux Corporation Obesity treatment
JP4463762B2 (en) 2003-06-16 2010-05-19 エシコン・エンド−サージェリィ・インコーポレイテッドEthicon Endo−Surgery,Inc. Surgical system with a stapling instrument and the retractor
US7320696B2 (en) 2003-06-24 2008-01-22 Bashir Mussa Gazi Semi-stationary balloon in the gastric antrum provided with connecting an anchoring rod for inducing weight reduction in human beings
KR20030068070A (en) 2003-06-26 2003-08-19 이정환 The method of endoscopic ballooning for the treatment of obesity
US20090259236A2 (en) 2003-07-28 2009-10-15 Baronova, Inc. Gastric retaining devices and methods
US20050055365A1 (en) * 2003-09-09 2005-03-10 I.V. Ramakrishnan Scalable data extraction techniques for transforming electronic documents into queriable archives
US20050075654A1 (en) 2003-10-06 2005-04-07 Brian Kelleher Methods and devices for soft tissue securement
US8206456B2 (en) 2003-10-10 2012-06-26 Barosense, Inc. Restrictive and/or obstructive implant system for inducing weight loss
US20050080444A1 (en) 2003-10-14 2005-04-14 Kraemer Stefan J.M. Transesophageal gastric reduction device, system and method
US7097650B2 (en) 2003-10-14 2006-08-29 Satiety, Inc. System for tissue approximation and fixation
US7914543B2 (en) 2003-10-14 2011-03-29 Satiety, Inc. Single fold device for tissue fixation
US20050085787A1 (en) 2003-10-17 2005-04-21 Laufer Michael D. Minimally invasive gastrointestinal bypass
US7736372B2 (en) 2003-11-13 2010-06-15 Usgi Medical, Inc. Apparatus and methods for endoscopic suturing
EP1708641A1 (en) 2003-12-09 2006-10-11 GI Dynamics, Inc. Intestinal sleeve
US7147140B2 (en) 2003-12-30 2006-12-12 Ethicon Endo - Surgery, Inc. Cartridge retainer for a curved cutter stapler
EP1713402A2 (en) 2004-02-13 2006-10-25 Satiety, Inc. Methods for reducing stomach volume
US8147561B2 (en) 2004-02-26 2012-04-03 Endosphere, Inc. Methods and devices to curb appetite and/or reduce food intake
US8628547B2 (en) 2004-03-09 2014-01-14 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US9028511B2 (en) 2004-03-09 2015-05-12 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US8252009B2 (en) 2004-03-09 2012-08-28 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US7703459B2 (en) 2004-03-09 2010-04-27 Usgi Medical, Inc. Apparatus and methods for mapping out endoluminal gastrointestinal surgery
US7255675B2 (en) 2004-03-23 2007-08-14 Michael Gertner Devices and methods to treat a patient
US20060195139A1 (en) 2004-03-23 2006-08-31 Michael Gertner Extragastric devices and methods for gastroplasty
EP1750627A2 (en) 2004-03-26 2007-02-14 Satiety, Inc. Systems and methods for treating obesity
GB2413769B (en) 2004-04-06 2007-02-21 Medevert Ltd Ureteric stents
WO2005105003A1 (en) 2004-04-26 2005-11-10 Synecor, Llc Restrictive and/or obstructive implant for inducing weight loss
EP1744804A4 (en) 2004-05-03 2009-11-04 Fulfillium Inc Method and system for gastric volume control
US20050251176A1 (en) 2004-05-07 2005-11-10 Usgi Medical Inc. System for treating gastroesophageal reflux disease
US7621925B2 (en) 2004-05-07 2009-11-24 Usgi Medical, Inc. Needle assembly for tissue manipulation
US8444657B2 (en) 2004-05-07 2013-05-21 Usgi Medical, Inc. Apparatus and methods for rapid deployment of tissue anchors
US20060135971A1 (en) 2004-05-07 2006-06-22 Usgi Medical Inc. System for treating gastroesophageal reflux disease
US7347863B2 (en) 2004-05-07 2008-03-25 Usgi Medical, Inc. Apparatus and methods for manipulating and securing tissue
US7520884B2 (en) 2004-05-07 2009-04-21 Usgi Medical Inc. Methods for performing gastroplasty
US7918869B2 (en) 2004-05-07 2011-04-05 Usgi Medical, Inc. Methods and apparatus for performing endoluminal gastroplasty
US7112186B2 (en) 2004-05-26 2006-09-26 Shah Tilak M Gastro-occlusive device
US8475476B2 (en) 2004-06-01 2013-07-02 Cook Medical Technologies Llc System and method for accessing a body cavity
WO2005120363A8 (en) 2004-06-03 2007-09-07 Mayo Foundation Obesity treatment and device
US7931661B2 (en) 2004-06-14 2011-04-26 Usgi Medical, Inc. Apparatus and methods for performing transluminal gastrointestinal procedures
EP1768618B1 (en) 2004-07-09 2011-04-20 GI Dynamics, Inc. Devices for placing a gastrointestinal sleeve
EP1799145B1 (en) 2004-09-17 2016-12-21 GI Dynamics, Inc. Gastrointestinal anchor
US7850704B2 (en) 2004-09-27 2010-12-14 Theranova, Llc Method and apparatus for anchoring implants
ES2582334T3 (en) 2004-10-15 2016-09-12 Bfkw, Llc bariatric device
US20060155259A1 (en) 2005-01-13 2006-07-13 Maclay Alistair Stomach balloon that can be inserted and removed via mouth
US8087413B2 (en) 2005-01-14 2012-01-03 Usgi Medical Inc. Attenuation of environmental parameters on a gastric lumen
US7766973B2 (en) 2005-01-19 2010-08-03 Gi Dynamics, Inc. Eversion resistant sleeves
US7771382B2 (en) 2005-01-19 2010-08-10 Gi Dynamics, Inc. Resistive anti-obesity devices
US7699863B2 (en) 2005-03-01 2010-04-20 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
US7785291B2 (en) 2005-03-01 2010-08-31 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
US7674271B2 (en) 2005-05-04 2010-03-09 InTailor Surgical, Inc. Endoluminal gastric ring and method
EP1883370B1 (en) 2005-05-23 2011-08-03 Synecor, LLC Restrictive and/or obstructive implant system for inducing weight loss
JP2009506799A (en) 2005-06-03 2009-02-19 タイコ ヘルスケア グループ リミテッド パートナーシップ Powered surgical instruments
US7828812B2 (en) 2005-06-13 2010-11-09 Ethicon Endo-Surgery, Inc. Surgical suturing apparatus with needle release system
US7896894B2 (en) 2005-08-05 2011-03-01 Ethicon Endo-Surgery, Inc. Apparatus for single pass gastric restriction
US7771440B2 (en) 2005-08-18 2010-08-10 Ethicon Endo-Surgery, Inc. Method and apparatus for endoscopically performing gastric reduction surgery in a single pass
US7896890B2 (en) 2005-09-02 2011-03-01 Ethicon Endo-Surgery, Inc. Method and apparatus for endoscopically performing gastric reduction surgery in a single step
US20080190989A1 (en) 2005-10-03 2008-08-14 Crews Samuel T Endoscopic plication device and method
US9055942B2 (en) 2005-10-03 2015-06-16 Boston Scienctific Scimed, Inc. Endoscopic plication devices and methods
US20090125040A1 (en) 2006-09-13 2009-05-14 Hambly Pablo R Tissue acquisition devices and methods
ES2395783T3 (en) 2005-10-03 2013-02-15 Barosense, Inc. Endoscopic devices furrowed
US20070100369A1 (en) 2005-10-31 2007-05-03 Cragg Andrew H Intragastric space filler
US8216268B2 (en) 2005-12-22 2012-07-10 Cook Medical Technologies Llc Intragastric bag for treating obesity
CA2634614C (en) 2005-12-22 2011-07-26 Wilson-Cook Medical Inc. Coiled intragastric member for treating obesity
US8726909B2 (en) 2006-01-27 2014-05-20 Usgi Medical, Inc. Methods and apparatus for revision of obesity procedures
US20070191871A1 (en) 2006-02-10 2007-08-16 Endogastric Solutions, Inc. Transesophageal gastric reduction method and device for reducing the size of a previously formed gastric reduction pouch
US20070191870A1 (en) 2006-02-10 2007-08-16 Endogastric Solutions, Inc. Transesophageal gastric reduction method and device for practicing same
US7881797B2 (en) 2006-04-25 2011-02-01 Valentx, Inc. Methods and devices for gastrointestinal stimulation
US7819836B2 (en) 2006-06-23 2010-10-26 Gi Dynamics, Inc. Resistive anti-obesity devices
US7615064B2 (en) 2006-07-26 2009-11-10 J.n Tailor Surgical, Inc. Endolumenal gastric ring with suspended impeding member
US20080097510A1 (en) 2006-09-01 2008-04-24 Albrecht Thomas E Method for inducing weight loss with a patient
EP2572673B1 (en) 2006-09-02 2015-08-19 Boston Scientific Scimed, Inc. Intestinal sleeves and associated deployment systems and methods
WO2008033474A3 (en) 2006-09-15 2008-05-22 Synecor Llc System for anchoring stomach implant
US20080234703A1 (en) 2007-03-23 2008-09-25 Ethicon Endo-Surgery, Inc. Tissue approximation system
US20080294179A1 (en) 2007-05-12 2008-11-27 Balbierz Daniel J Devices and methods for stomach partitioning
US8142469B2 (en) 2007-06-25 2012-03-27 Reshape Medical, Inc. Gastric space filler device, delivery system, and related methods
US20090030284A1 (en) 2007-07-18 2009-01-29 David Cole Overtube introducer for use in endoscopic bariatric surgery
CA2696993C (en) 2007-07-18 2017-01-03 Samuel T. Crews Endoscopic implant system and method
US20090171383A1 (en) 2007-12-31 2009-07-02 David Cole Gastric space occupier systems and methods of use
US8020741B2 (en) 2008-03-18 2011-09-20 Barosense, Inc. Endoscopic stapling devices and methods
US7934631B2 (en) 2008-11-10 2011-05-03 Barosense, Inc. Multi-fire stapling systems and methods for delivering arrays of staples
JP5753849B2 (en) 2009-10-07 2015-07-22 ランペ・ホールディングス・ベー・フェー Ambulatory ladder is equipped with a stand-off device

Patent Citations (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1408865A (en) * 1921-07-13 1922-03-07 Selden S Cowell Collapsible funnel
US4134405A (en) * 1977-01-10 1979-01-16 Smit Julie A Catheter and intestine tube and method of using the same
US4315509A (en) * 1977-01-10 1982-02-16 Smit Julie A Insertion and removal catheters and intestinal tubes for restricting absorption
US4641653A (en) * 1978-06-02 1987-02-10 Rockey Arthur G Medical sleeve
US4501264A (en) * 1978-06-02 1985-02-26 Rockey Arthur G Medical sleeve
US4246893A (en) * 1978-07-05 1981-01-27 Daniel Berson Inflatable gastric device for treating obesity
US4441215A (en) * 1980-11-17 1984-04-10 Kaster Robert L Vascular graft
US4899747A (en) * 1981-12-10 1990-02-13 Garren Lloyd R Method and appartus for treating obesity
US4403604A (en) * 1982-05-13 1983-09-13 Wilkinson Lawrence H Gastric pouch
US4607618A (en) * 1983-02-23 1986-08-26 Angelchik Jean P Method for treatment of morbid obesity
US4648383A (en) * 1985-01-11 1987-03-10 Angelchik Jean P Peroral apparatus for morbid obesity treatment
US4723547A (en) * 1985-05-07 1988-02-09 C. R. Bard, Inc. Anti-obesity balloon placement system
US4747849A (en) * 1986-01-13 1988-05-31 Claude Galtier Oesophagus prosthesis
US4694827A (en) * 1986-01-14 1987-09-22 Weiner Brian C Inflatable gastric device for treating obesity and method of using the same
US4997084A (en) * 1988-05-13 1991-03-05 Opielab, Inc. Packaging system for disposable endoscope sheaths
US4846836A (en) * 1988-10-03 1989-07-11 Reich Jonathan D Artificial lower gastrointestinal valve
US5709657A (en) * 1989-06-28 1998-01-20 Zimmon Science Corporation Methods for placement of balloon tamponade devices
US5314473A (en) * 1989-07-20 1994-05-24 Godin Norman J Prosthesis for preventing gastric reflux into the esophagus
US5234454A (en) * 1991-08-05 1993-08-10 Akron City Hospital Percutaneous intragastric balloon catheter and method for controlling body weight therewith
US5662713A (en) * 1991-10-09 1997-09-02 Boston Scientific Corporation Medical stents for body lumens exhibiting peristaltic motion
US5290217A (en) * 1991-10-10 1994-03-01 Earl K. Sipes Method and apparatus for hernia repair
US5720776A (en) * 1991-10-25 1998-02-24 Cook Incorporated Barb and expandable transluminal graft prosthesis for repair of aneurysm
US5211658A (en) * 1991-11-05 1993-05-18 New England Deaconess Hospital Corporation Method and device for performing endovascular repair of aneurysms
US5593434A (en) * 1992-01-31 1997-01-14 Advanced Cardiovascular Systems, Inc. Stent capable of attachment within a body lumen
US5405377A (en) * 1992-02-21 1995-04-11 Endotech Ltd. Intraluminal stent
US5401241A (en) * 1992-05-07 1995-03-28 Inamed Development Co. Duodenal intubation catheter
US5246456A (en) * 1992-06-08 1993-09-21 Wilkinson Lawrence H Fenestrated gastric pouch
US5327914A (en) * 1992-09-02 1994-07-12 Shlain Leonard M Method and devices for use in surgical gastroplastic procedure
US5345949A (en) * 1992-09-02 1994-09-13 Shlain Leonard M Methods for use in surgical gastroplastic procedure
US5306300A (en) * 1992-09-22 1994-04-26 Berry H Lee Tubular digestive screen
US5609624A (en) * 1993-10-08 1997-03-11 Impra, Inc. Reinforced vascular graft and method of making same
US5653743A (en) * 1994-09-09 1997-08-05 Martin; Eric C. Hypogastric artery bifurcation graft and method of implantation
US5514176A (en) * 1995-01-20 1996-05-07 Vance Products Inc. Pull apart coil stent
US5861036A (en) * 1995-03-28 1999-01-19 Biomedix S.A. Switzerland Medical prosthesis for preventing gastric reflux in the esophagus
US5628786A (en) * 1995-05-12 1997-05-13 Impra, Inc. Radially expandable vascular graft with resistance to longitudinal compression and method of making same
US5749918A (en) * 1995-07-20 1998-05-12 Endotex Interventional Systems, Inc. Intraluminal graft and method for inserting the same
US6102922A (en) * 1995-09-22 2000-08-15 Kirk Promotions Limited Surgical method and device for reducing the food intake of patient
US5771903A (en) * 1995-09-22 1998-06-30 Kirk Promotions Limited Surgical method for reducing the food intake of a patient
US5720657A (en) * 1995-11-10 1998-02-24 Denso Corporation Air passage switching device and air conditioning apparatus using the same
US5922019A (en) * 1995-11-27 1999-07-13 Schneider (Europe) A.G. Conical stent
US6596023B1 (en) * 1996-05-24 2003-07-22 Meadox Medicals, Inc. Shaped woven tubular soft-tissue prostheses and method of manufacturing the same
US5855601A (en) * 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same
US6016848A (en) * 1996-07-16 2000-01-25 W. L. Gore & Associates, Inc. Fluoropolymer tubes and methods of making same
US6287334B1 (en) * 1996-12-18 2001-09-11 Venpro Corporation Device for regulating the flow of blood through the blood system
US5868141A (en) * 1997-05-14 1999-02-09 Ellias; Yakub A. Endoscopic stomach insert for treating obesity and method for use
US5887594A (en) * 1997-09-22 1999-03-30 Beth Israel Deaconess Medical Center Inc. Methods and devices for gastroesophageal reflux reduction
US6120534A (en) * 1997-10-29 2000-09-19 Ruiz; Carlos E. Endoluminal prosthesis having adjustable constriction
US6254642B1 (en) * 1997-12-09 2001-07-03 Thomas V. Taylor Perorally insertable gastroesophageal anti-reflux valve prosthesis and tool for implantation thereof
US6558429B2 (en) * 1997-12-09 2003-05-06 Reflux Corporation Perorally insertable gastroesophageal anti-reflux valve prosthesis and tool for implantation thereof
US20010020190A1 (en) * 1997-12-09 2001-09-06 Taylor Thomas V. Perorally insertable gastroesophageal anti-reflux valve prosthesis and tool for implantation thereof
US20010020189A1 (en) * 1997-12-09 2001-09-06 Taylor Thomas V. Sutureless gastroesophageal anti-reflux valve prosthesis and tool for peroral implantation thereof
US6544291B2 (en) * 1997-12-09 2003-04-08 Thomas V. Taylor Sutureless gastroesophageal anti-reflux valve prosthesis and tool for peroral implantation thereof
US6258120B1 (en) * 1997-12-23 2001-07-10 Embol-X, Inc. Implantable cerebral protection device and methods of use
US7575586B2 (en) * 1998-01-30 2009-08-18 St. Jude Medical Atg, Inc. Medical graft connector or plug structures, and methods of making and installing same
US6113609A (en) * 1998-05-26 2000-09-05 Scimed Life Systems, Inc. Implantable tissue fastener and system for treating gastroesophageal reflux disease
US6264700B1 (en) * 1998-08-27 2001-07-24 Endonetics, Inc. Prosthetic gastroesophageal valve
US6547801B1 (en) * 1998-09-14 2003-04-15 Sofradim Production Gastric constriction device
US20010021796A1 (en) * 1998-12-11 2001-09-13 Enteric Medical Technologies, Inc. Method for treating tissue and apparatus for use therewith
US6575896B2 (en) * 1998-12-11 2003-06-10 Scimed Life Systems, Inc. Method for treating tissue and apparatus for use therewith
US6425916B1 (en) * 1999-02-10 2002-07-30 Michi E. Garrison Methods and devices for implanting cardiac valves
US20010011543A1 (en) * 1999-08-12 2001-08-09 Peter Forsell Controlled food flow in a patient
US20030009236A1 (en) * 1999-12-13 2003-01-09 Norman Godin Prosthesis for controlling the direction of flow in a duct of a living organism
US6764518B2 (en) * 1999-12-13 2004-07-20 Biomedix S.A. Prosthesis for controlling the direction of flow in a duct of a living organism
US6503264B1 (en) * 2000-03-03 2003-01-07 Bioenterics Corporation Endoscopic device for removing an intragastric balloon
US6540789B1 (en) * 2000-06-15 2003-04-01 Scimed Life Systems, Inc. Method for treating morbid obesity
US6572629B2 (en) * 2000-08-17 2003-06-03 Johns Hopkins University Gastric reduction endoscopy
US20020022851A1 (en) * 2000-08-17 2002-02-21 Johns Hopkins University Gastric reduction endoscopy
US20020099439A1 (en) * 2000-09-29 2002-07-25 Schwartz Robert S. Venous valvuloplasty device and method
US20020055757A1 (en) * 2000-11-03 2002-05-09 Torre Roger De La Method and device for use in minimally invasive placement of intragastric devices
US6572627B2 (en) * 2001-01-08 2003-06-03 Shlomo Gabbay System to inhibit and/or control expansion of anatomical features
US7220285B2 (en) * 2001-02-02 2007-05-22 L'oreal S.A. Pulverulent composition for bleaching human keratin fibers
US7011094B2 (en) * 2001-03-02 2006-03-14 Emphasys Medical, Inc. Bronchial flow control devices and methods of use
US6558400B2 (en) * 2001-05-30 2003-05-06 Satiety, Inc. Obesity treatment tools and methods
US6675809B2 (en) * 2001-08-27 2004-01-13 Richard S. Stack Satiation devices and methods
US7354454B2 (en) * 2001-08-27 2008-04-08 Synecor, Llc Satiation devices and methods
US20040117031A1 (en) * 2001-08-27 2004-06-17 Stack Richard S. Satiation devices and methods
US6845776B2 (en) * 2001-08-27 2005-01-25 Richard S. Stack Satiation devices and methods
US20040138761A1 (en) * 2001-08-27 2004-07-15 Stack Richard S. Satiation devices and methods
US6740121B2 (en) * 2001-11-09 2004-05-25 Boston Scientific Corporation Intragastric stent for duodenum bypass
US7335210B2 (en) * 2002-04-03 2008-02-26 Julie Ann Smit Endoscope and tools for applying sealants and adhesives and intestinal lining for reducing food absorption
US7211114B2 (en) * 2002-08-26 2007-05-01 The Trustees Of Columbia University In The City Of New York Endoscopic gastric bypass
US20080033574A1 (en) * 2002-08-26 2008-02-07 Marc Bessler Endoscopic Gastric Bypass
US20050149114A1 (en) * 2002-08-29 2005-07-07 Cartledge Richard G. Apparatus for implanting surgical devices for controlling the internal circumference of an anatomic orifice or lumen
US7229428B2 (en) * 2002-10-23 2007-06-12 Satiety, Inc. Method and device for use in endoscopic organ procedures
US7220237B2 (en) * 2002-10-23 2007-05-22 Satiety, Inc. Method and device for use in endoscopic organ procedures
US7037344B2 (en) * 2002-11-01 2006-05-02 Valentx, Inc. Apparatus and methods for treatment of morbid obesity
US20070010864A1 (en) * 2002-11-01 2007-01-11 Mitchell Dann Gastrointestinal implant system
US20040092892A1 (en) * 2002-11-01 2004-05-13 Jonathan Kagan Apparatus and methods for treatment of morbid obesity
US20040148034A1 (en) * 2002-11-01 2004-07-29 Jonathan Kagan Apparatus and methods for treatment of morbid obesity
US20070198074A1 (en) * 2002-11-01 2007-08-23 Mitchell Dann Devices and methods for endolumenal gastrointestinal bypass
US7025791B2 (en) * 2002-12-02 2006-04-11 Gi Dynamics, Inc. Bariatric sleeve
US7347875B2 (en) * 2002-12-02 2008-03-25 Gi Dynamics, Inc. Methods of treatment using a bariatric sleeve
US20040107004A1 (en) * 2002-12-02 2004-06-03 Seedling Enterprises, Llc Bariatric sleeve
US7315509B2 (en) * 2003-01-10 2008-01-01 Samsung Electronics Co., Ltd. Method for recovering from a received data error in a mobile communication system providing a multimedia broadcast/multicast service
US20040143342A1 (en) * 2003-01-16 2004-07-22 Stack Richard S. Satiation pouches and methods of use
US7097665B2 (en) * 2003-01-16 2006-08-29 Synecor, Llc Positioning tools and methods for implanting medical devices
US20050096673A1 (en) * 2003-10-10 2005-05-05 Stack Richard S. Devices and methods for retaining a gastro-esophageal implant
US20090018558A1 (en) * 2006-10-04 2009-01-15 Michael Laufer Methods of organ reconfiguration

Cited By (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9788984B2 (en) 2001-08-27 2017-10-17 Boston Scientific Scimed, Inc. Satiation devices and methods
US20040117031A1 (en) * 2001-08-27 2004-06-17 Stack Richard S. Satiation devices and methods
US9138340B2 (en) 2001-08-27 2015-09-22 Boston Scientific Scimed, Inc. Gastro-esophageal implants
US20080269797A1 (en) * 2001-08-27 2008-10-30 Stack Richard S Satiation devices and methods
US7833280B2 (en) 2001-08-27 2010-11-16 Barosense, Inc. Satiation devices and methods
US8784354B2 (en) 2001-08-27 2014-07-22 Boston Scientific Scimed, Inc. Positioning tools and methods for implanting medical devices
US9180036B2 (en) 2001-08-27 2015-11-10 Boston Scientific Scimed, Inc. Methods for implanting medical devices
US9358144B2 (en) * 2001-08-27 2016-06-07 Boston Scientific Scimed, Inc. Gastrointestinal implants
US9872786B2 (en) 2001-08-27 2018-01-23 Boston Scientific Scimed, Inc. Gastro-esophageal implants
US7981162B2 (en) * 2001-08-27 2011-07-19 Barosense, Inc. Satiation devices and methods
US20150202039A1 (en) * 2001-08-27 2015-07-23 Boston Scientific Scimed, Inc. Gastrointestinal implants
US20030199991A1 (en) * 2001-08-27 2003-10-23 Stack Richard S. Satiation devices and methods
US8568488B2 (en) 2001-08-27 2013-10-29 Boston Scientific Scimed, Inc. Satiation devices and methods
US20110270410A1 (en) * 2001-08-27 2011-11-03 Barosense, Inc. Satiation devices and methods
US9107727B2 (en) 2001-08-27 2015-08-18 Boston Scientific Scimed, Inc. Satiation devices and methods
US9844453B2 (en) 2001-08-27 2017-12-19 Boston Scientific Scimed, Inc. Positioning tools and methods for implanting medical devices
US8992457B2 (en) * 2001-08-27 2015-03-31 Boston Scientific Scimed, Inc. Gastrointestinal implants
US8845753B2 (en) 2001-08-27 2014-09-30 Boston Scientific Scimed, Inc. Satiation devices and methods
US9254214B2 (en) 2001-08-27 2016-02-09 Boston Scientific Scimed, Inc. Satiation devices and methods
US8337566B2 (en) 2002-04-08 2012-12-25 Barosense, Inc. Method and apparatus for modifying the exit orifice of a satiation pouch
US7846138B2 (en) 2002-11-01 2010-12-07 Valentx, Inc. Cuff and sleeve system for gastrointestinal bypass
US8968270B2 (en) 2002-11-01 2015-03-03 Valentx, Inc. Methods of replacing a gastrointestinal bypass sleeve for therapy adjustment
US8070743B2 (en) 2002-11-01 2011-12-06 Valentx, Inc. Devices and methods for attaching an endolumenal gastrointestinal implant
US9060844B2 (en) 2002-11-01 2015-06-23 Valentx, Inc. Apparatus and methods for treatment of morbid obesity
US8182459B2 (en) 2002-11-01 2012-05-22 Valentx, Inc. Devices and methods for endolumenal gastrointestinal bypass
US9839546B2 (en) 2002-11-01 2017-12-12 Valentx, Inc. Apparatus and methods for treatment of morbid obesity
US9561127B2 (en) 2002-11-01 2017-02-07 Valentx, Inc. Apparatus and methods for treatment of morbid obesity
US8012135B2 (en) 2002-11-01 2011-09-06 Valentx, Inc. Attachment cuff for gastrointestinal implant
US8012140B1 (en) 2002-11-01 2011-09-06 Valentx, Inc. Methods of transmural attachment in the gastrointestinal system
US7892214B2 (en) 2002-11-01 2011-02-22 Valentx, Inc. Attachment system for transmural attachment at the gastroesophageal junction
US8029455B2 (en) 2003-01-16 2011-10-04 Barosense, Inc. Satiation pouches and methods of use
US9248038B2 (en) 2003-10-10 2016-02-02 Boston Scientific Scimed, Inc. Methods for retaining a gastro-esophageal implant
US9445791B2 (en) 2003-10-10 2016-09-20 Boston Scientific Scimed, Inc. Systems and methods related to gastro-esophageal implants
US9180035B2 (en) 2003-10-10 2015-11-10 Boston Scientific Scimed, Inc. Devices and methods for retaining a gastro-esophageal implant
US8241202B2 (en) 2004-04-26 2012-08-14 Barosense, Inc. Restrictive and/or obstructive implant for inducing weight loss
US8845673B2 (en) 2005-03-01 2014-09-30 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants and methods for use thereof
US8864784B2 (en) 2005-03-01 2014-10-21 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
US8267888B2 (en) 2005-03-01 2012-09-18 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
US8858496B2 (en) 2005-03-01 2014-10-14 Tulip Medical Ltd. Bioerodible self-deployable intragastric implants
US8469977B2 (en) 2005-10-03 2013-06-25 Barosense, Inc. Endoscopic plication device and method
US7881797B2 (en) 2006-04-25 2011-02-01 Valentx, Inc. Methods and devices for gastrointestinal stimulation
US9314361B2 (en) 2006-09-15 2016-04-19 Boston Scientific Scimed, Inc. System and method for anchoring stomach implant
US20080167629A1 (en) * 2006-09-25 2008-07-10 Valentx, Inc. Methods for toposcopic sleeve delivery
US8118774B2 (en) 2006-09-25 2012-02-21 Valentx, Inc. Toposcopic access and delivery devices
US8808270B2 (en) 2006-09-25 2014-08-19 Valentx, Inc. Methods for toposcopic sleeve delivery
US8182441B2 (en) 2007-06-08 2012-05-22 Valentx, Inc. Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices
US8945167B2 (en) 2007-12-31 2015-02-03 Boston Scientific Scimed, Inc. Gastric space occupier systems and methods of use
US8864008B2 (en) 2008-03-18 2014-10-21 Boston Scientific Scimed, Inc. Endoscopic stapling devices and methods
US9636114B2 (en) 2008-03-18 2017-05-02 Boston Scientific Scimed, Inc. Endoscopic stapling devices
US9451956B2 (en) 2008-11-10 2016-09-27 Boston Scientific Scimed, Inc. Multi-fire stapling systems
US7934631B2 (en) 2008-11-10 2011-05-03 Barosense, Inc. Multi-fire stapling systems and methods for delivering arrays of staples
US8747421B2 (en) 2008-11-10 2014-06-10 Boston Scientific Scimed, Inc. Multi-fire stapling systems and methods for delivering arrays of staples
US8702641B2 (en) 2009-04-03 2014-04-22 Metamodix, Inc. Gastrointestinal prostheses having partial bypass configurations
US8211186B2 (en) 2009-04-03 2012-07-03 Metamodix, Inc. Modular gastrointestinal prostheses
US9173760B2 (en) 2009-04-03 2015-11-03 Metamodix, Inc. Delivery devices and methods for gastrointestinal implants
US9044300B2 (en) 2009-04-03 2015-06-02 Metamodix, Inc. Gastrointestinal prostheses
US9278019B2 (en) 2009-04-03 2016-03-08 Metamodix, Inc Anchors and methods for intestinal bypass sleeves
US20120041465A1 (en) * 2009-04-30 2012-02-16 Tidhar Shalon Devices and methods for treating gastrointestinal and metabolic disorders
US8961539B2 (en) 2009-05-04 2015-02-24 Boston Scientific Scimed, Inc. Endoscopic implant system and method
US8282598B2 (en) 2009-07-10 2012-10-09 Metamodix, Inc. External anchoring configurations for modular gastrointestinal prostheses
US8702642B2 (en) 2009-07-10 2014-04-22 Metamodix, Inc. External anchoring configurations for modular gastrointestinal prostheses
US9877860B2 (en) * 2009-10-26 2018-01-30 Apollo Endosurgery Us, Inc. Bariatric device and method for weight loss
US20120203061A1 (en) * 2009-10-26 2012-08-09 Allergan, Inc. Bariatric device and method for weight loss
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US20130268089A1 (en) * 2010-08-10 2013-10-10 Ram Weiss Adapter for stomach devices
EP2841020B1 (en) * 2012-04-27 2017-07-26 Cook Medical Technologies LLC Anti-aspiration prosthesis
US9681975B2 (en) 2012-05-31 2017-06-20 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9675489B2 (en) 2012-05-31 2017-06-13 Valentx, Inc. Devices and methods for gastrointestinal bypass
US8956318B2 (en) 2012-05-31 2015-02-17 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9050168B2 (en) 2012-05-31 2015-06-09 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9173759B2 (en) 2012-05-31 2015-11-03 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9566181B2 (en) 2012-05-31 2017-02-14 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9039649B2 (en) 2012-05-31 2015-05-26 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9451960B2 (en) 2012-05-31 2016-09-27 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9757264B2 (en) 2013-03-13 2017-09-12 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9622897B1 (en) 2016-03-03 2017-04-18 Metamodix, Inc. Pyloric anchors and methods for intestinal bypass sleeves

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US8568488B2 (en) 2013-10-29 grant
US8845753B2 (en) 2014-09-30 grant
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US9358144B2 (en) 2016-06-07 grant
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US9872786B2 (en) 2018-01-23 grant
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US20100016988A1 (en) 2010-01-21 application
US20150202039A1 (en) 2015-07-23 application

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