US20060190037A1 - Integrated vascular device with puncture site closure component and sealant and methods of use - Google Patents

Integrated vascular device with puncture site closure component and sealant and methods of use Download PDF

Info

Publication number
US20060190037A1
US20060190037A1 US11/344,868 US34486806A US2006190037A1 US 20060190037 A1 US20060190037 A1 US 20060190037A1 US 34486806 A US34486806 A US 34486806A US 2006190037 A1 US2006190037 A1 US 2006190037A1
Authority
US
United States
Prior art keywords
opening
tissue
sheath
closure component
method according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11/344,868
Inventor
Richard Ginn
W. Belef
Original Assignee
Ginn Richard S
Belef W M
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US09/478,179 priority Critical patent/US6197042B1/en
Priority to US10/147,774 priority patent/US7931669B2/en
Application filed by Ginn Richard S, Belef W M filed Critical Ginn Richard S
Priority to US11/344,868 priority patent/US20060190037A1/en
Publication of US20060190037A1 publication Critical patent/US20060190037A1/en
Application status is Abandoned legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/10Surgical instruments, devices or methods, e.g. tourniquets for applying or removing wound clamps, e.g. containing only one clamp or staple; Wound clamp magazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/08Wound clamps or clips, i.e. not or only partly penetrating the tissue ; Devices for bringing together the edges of a wound
    • A61B17/083Clips, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/128Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491Surgical glue applicators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064Surgical staples, i.e. penetrating the tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00637Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for sealing trocar wounds through abdominal wall
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646Type of implements
    • A61B2017/00663Type of implements the implement being a suture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646Type of implements
    • A61B2017/00668Type of implements the implement being a tack or a staple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831Material properties
    • A61B2017/00862Material properties elastic or resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064Surgical staples, i.e. penetrating the tissue
    • A61B2017/0641Surgical staples, i.e. penetrating the tissue having at least three legs as part of one single body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/06Body-piercing guide needles or the like
    • A61M25/0662Guide tubes

Abstract

Apparatus and methods are provided for use in sealing a vascular puncture site. The invention comprises an integrated vascular device having a sheath with a closure component and puncture sealant. The closure component is disposed on and advanceable over the exterior of the sheath and may comprise any of a variety of apparatus suited for closing a vascular puncture. Once the closure component has been actuated to close the puncture, sealant is introduced to seal the puncture. The sheath and closure component are then removed from the patient.

Description

    CROSS-REFERENCE TO RELATED APPLICATIONS
  • This application is a divisional of U.S. patent application Ser. No. 10/147,774, filed May 17, 2002, which is a continuation-in-part of U.S. patent application Ser. No. 09/478,179 filed Jan. 5, 2000, now U.S. Pat. No. 6,197,042, the disclosures of which are each incorporated by reference herein.
  • BACKGROUND OF THE INVENTION
  • 1. The Field of the Invention
  • The present invention relates to apparatus and methods for sealing an iatrogenic puncture in a vessel formed in conjunction with a diagnostic or therapeutic treatment. More particularly, the present invention provides an integrated vascular device comprising a sheath having a puncture closure components and puncture sealant.
  • 2. The Relevant Technology
  • Catheterization and interventional procedures, such as angioplasty and stenting, generally are performed by inserting a hollow needle through a patient's skin and muscle tissue into the vascular system. A guide wire then is passed through the needle lumen into the patient's blood vessel. The needle is removed and an introducer sheath is advanced over the guide wire into the vessel. A catheter typically is passed through the lumen of the introducer sheath and advanced over the guide wire into position for a medical procedure. The introducer sheath therefore facilitates insertion of various devices into the vessel while minimizing trauma to the vessel wall and minimizing blood loss during a procedure.
  • Upon completion of the medical procedure, the catheter and introducer sheath are removed, leaving a puncture site in the vessel. Commonly, external pressure is applied until clotting and wound sealing occurs. However, this procedure is time consuming and expensive, requiring as much as an hour of a physician's or nurse's time, is uncomfortable for the patient, and requires that the patient be immobilized in the operating room, cathlab, or holding area. Furthermore, a risk of hematoma exists from bleeding prior to hemostasis.
  • Various apparatus have been developed for percutaneously sealing a vascular puncture by occluding or suturing the puncture site. For example, U.S. Pat. Nos. 5,192,302 and 5,222,974 to Kensey et al. describe the use of a biodegradable plug delivered through the introducer sheath into the puncture site. When deployed, the plug seals the vessel and provides hemostasis. Such devices have been slow to gain acceptance in the medical community, however, due to difficulties encountered in positioning the plug within the vessel.
  • Another previously known technique comprises percutaneously suturing the puncture site with specialized apparatus. Such apparatus is described, for example, in U.S. Pat. No. 5,304,184 to Hathaway et al. While percutaneous suturing devices may be effective, a significant degree of skill may be required on the part of the practitioner. Because such devices are mechanically complex, they tend to be relatively expensive to manufacture.
  • Surgical staples and resilient clips for external skin wound closure are well known in the art. Examples include U.S. Pat. No. 5,026,390 to Brown and U.S. Pat. No. 5,683,405 to Yacoubian et al, which both describe resiliently deformable closure devices suitable for manual external application.
  • To reduce the cost and complexity of percutaneous puncture closure devices, such devices employing resilient or deformable clips have been developed. U.S. Pat. No. 5,478,354 to Tovey et al. describes the use of resilient clips in conjunction with a trocar to close abdominal puncture wounds. U.S. Pat. No. 5,810,846 to Virnich et al. describes a specialized apparatus for closing a vascular puncture site with a plastically deformable clip. The apparatus preferably is advanced over a guide wire through a cannula to the surface of the puncture site, where the staple-like clips are delivered to close the wound.
  • U.S. Pat. No. 5,782,861 to Cragg et al. describes specialized apparatus for closing a puncture site with a detachable clip. The apparatus comprises a hollow shaft having a distal end formed with one or more opposed pairs of resilient grasping prongs and that is advanced over a guide wire through a coaxial hollow tube to a position at the distal end of the tube just proximal of the puncture. The grasping prongs are extended beyond the distal end of the tube to grasp the vessel on opposing sides of the puncture. The shaft then is partially retracted, causing the prongs to contract within the tube, thereby sealing the puncture site.
  • The use of backbleed indication as a positioning technique within a vascular puncture is known. For example, U.S. Pat. No. 4,317,445 to Robinson describes a flashback chamber for providing visual indication of venous entry of a cannula. However, that device does not discuss vascular wound closure. U.S. Pat. No. 5,676,689 to Kensey et al., which claims priority from the U.S. Pat. No. 5,222,974 patent discussed above, uses a vessel location device to simplify positioning of the biodegradable plug. The vessel locator enables blood from the vessel to flow there through so that the position of the vessel may be determined. However, the Kensey system only proffers one closure device, and that device is complex and raises concerns about biocompatibility. It also requires the closure component to be positioned within the puncture, thereby increasing the likelihood of dangerous over-advancement of the plug into the vessel.
  • The percutaneous puncture closure devices described in the foregoing patents generally have the drawback that they require relatively complex mechanisms and require time consuming manipulation to achieve hemostasis. It therefore would be desirable to provide apparatus and methods suitable for vascular puncture closure that overcome these disadvantages of previously known devices.
  • It also would be desirable to provide apparatus and methods that quickly and effectively achieve hemostasis.
  • It further would be desirable to provide apparatus and methods wherein all foreign materials left in a patient's body are bioabsorbable.
  • It still further would be desirable to provide vascular puncture closure apparatus and methods that are safe, low cost, and easy to use.
  • BRIEF SUMMARY OF THE INVENTION
  • In view of the foregoing, it is an object of the present invention to provide vascular puncture closure apparatus and methods that overcome disadvantages of previously known devices.
  • It also is an object of this invention to provide apparatus and methods suitable for vascular puncture closure that quickly and effectively achieve hemostasis.
  • It further is an object of the present invention to provide apparatus and methods wherein all foreign materials left in a patient's body are bioabsorbable.
  • It still further is an object of the present invention to provide vascular puncture closure apparatus and methods that are safe, low cost, and easy to use.
  • These and other objects of the present invention are accomplished by provided an integrated vascular device comprising a sheath having a puncture closure component and puncture sealant. The closure component is disposed on and advanceable over the exterior of the sheath, which may, for example, comprise an introducer sheath, a trocar, or a catheter. The closure component may comprise any of a variety of apparatus suited to close a vascular puncture. Once the closure component has been actuated to close the puncture, sealant is introduced to the exterior surface of the closed puncture, preferably through the sheath's interior lumen, where the sealant seals the puncture closed. The sheath with closure component is then removed from the patient.
  • In a preferred embodiment constructed in accordance with the present invention, the closure component comprises a twist closure device. The device pierces tissue surrounding the vascular puncture and then is rotated to close the wound. In an alternative embodiment, the closure component comprises needles and an elastic segment surrounding the needles. The needles pierce the puncture with the elastic segment expanded. The segment is then allowed to resiliently contract to an unstressed configuration of smaller diameter, thereby drawing the needles together and closing the wound.
  • In a still further alternative embodiment, the needles, or prongs, are elastically deformed to an expanded diameter, in which they pierce the tissue adjacent to puncture. The needles then are allowed to resiliently contract to an unstressed configuration of smaller diameter, thereby closing the wound.
  • Sealant then may be introduced, preferably through the interior lumen of the sheath, to seal the puncture closed. The sealant may comprise any of a variety of sealants, per se known, including adhesives, sutures, and clips, all of which are preferably bioabsorbable. Alternatively, the closure component may further comprise the sealant, wherein the closure component is left in place within the vessel until hemostasis naturally occurs, or wherein the closure component comprises a monopolar electrode or opposed bipolar electrodes that cauterize the wound with RF current. In addition to cauterization, RF energy generates heat that beneficially causes shrinkage of the vascular tissue, thereby assisting closure of the wound. Thermal energy from electrical induction, infrared light, ultrasonic vibration, microwave or laser irradiation, and other means may also be used to seal the puncture.
  • Advantageously, the puncture closure component of the present invention is inexpensively integrated into a sheath, thereby minimizing mechanical complexity while providing quick, safe, effective, and easy-to-use apparatus for achieving vascular closure that overcomes drawbacks of previously known devices. Methods of using the apparatus of the present invention also are provided.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • The above and other objects and advantages of the present invention will be apparent upon consideration of the following detailed description, taken in conjunction with the accompanying drawings, in which like reference characters refer to like parts throughout, and in which:
  • FIG. 1 is a side view of a preferred embodiment of an integrated vascular device constructed in accordance with the present invention;
  • FIG. 2 is a side-sectional view of a sealing device for use with the vascular device of FIG. 1;
  • FIGS. 3A-3D are side views of the closure component of FIG. 1 in use at a vascular puncture site, shown in section, with the sealing device of FIG. 2, illustrating a method of sealing the puncture site;
  • FIGS. 4A-4D are top views of the vascular puncture site of FIG. 3, corresponding to the side-sectional views of FIG. 3, further illustrating the method of FIG. 3;
  • FIGS. 5A-5C are side-sectional views of an alternative embodiment of an integrated vascular device of the present invention in use at a vascular puncture site, illustrating a method of sealing the puncture site;
  • FIGS. 6A-6E are side-sectional views of a further alternative embodiment in use at a vascular puncture site, illustrating a method of sealing the puncture site; and
  • FIGS. 7A and 7B are isometric views of a section of vessel including and corresponding to the vascular puncture site of FIG. 6, further illustrating the method of FIG. 6.
  • DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
  • The integrated vascular sheath with closure component of the present invention overcomes disadvantages associated with previously known methods and apparatus for sealing a vascular puncture by providing a quick, simple, safe, low cost, effective, and easy-to-use solution to wound closure. Apparatus constructed in accordance with the present invention provide vascular access and wound closure in a single device, eliminating the time and manipulation required to insert a separate closure device at the completion of a procedure.
  • Referring to FIG. 1, a first embodiment of apparatus of the present invention is described. Vascular device 10 comprises sheath 12 coupled to hub 14, closure component 16, and closure actuator 18.
  • Sheath 12, which may, for example, comprise an introducer sheath, a trocar, or a catheter, includes central lumen 13 through which other devices may be introduced into the vasculature, for example, to perform a diagnostic or interventional procedure such as angiography, angioplasty, or stenting, or to seal a puncture site.
  • Hub 14 is mounted on the proximal end of sheath 12 and includes side port 20, arc lumens 22, and device port 24. Device port 24 communicates with central lumen 13 of sheath 12, and has self-sealing elastomeric membrane 25 disposed across it. Self-sealing membrane 25, which may comprise, for example, latex or a biocompatible synthetic rubber, permits interventional devices to be introduced through device port 24, while preventing blood loss through central lumen 13. Side port 20 of hub 14 is also in communication with central lumen 13, and is connected to hemostatic port 26 via biocompatible tubing 28.
  • In accordance with the principles of the present invention, closure component 16 comprises lumen 30 that receives sheath 12. Component 16 is slidably disposed on the exterior of sheath 12 and is movable from a stowed position, adjacent hub 14, to a distal deployment position, where tines 17 of component 16 are urged into engagement with tissue surrounding a vascular puncture. Closure component 16 comprises at least two sharpened tips, or tines 17. Tines 17 preferably comprise backbleed ports 32. Closure component 16 is rotatable within arc-lumens 22 about the longitudinal axis of sheath 12, so that, with tines 17 engaging tissue surrounding the vascular puncture, component 16 closes the puncture.
  • Closure actuator 18 comprises plunger 34 and tubes 36, which are configured to slidably pass through arc lumens 22 of hub 14. The proximal ends of tubes 36 are coupled to backbleed bores 38 of plunger 34. The distal ends of tubes 36 are mounted, either permanently or detachably, in closure component 16, so that movement of plunger 34 causes corresponding proximal or distal movement of closure component 16. Likewise, rotation of plunger 34 causes corresponding rotation of tubes 36 within arc lumens 22, which, in turn, rotates closure component 16 about the longitudinal axis of sheath 12.
  • Plunger 34 further comprises device bore 40, coaxially aligned with device port 24, and through which interventional devices or puncture sealants may be passed. As described in detail hereinafter, when plunger 34 is moved to its proximal-most position, closure component 16 is disposed adjacent to hub 14 and preferably provides adequate clearance for interventional devices to be inserted through device port 24 and central lumen 13 into the patient's vasculature. When moved to its distal-most position, plunger 34 causes tubes 36 to urge closure component 16 distally. Interventional devices or sealants then may be introduced through device bore 40, device port 24, and central lumen 13 into the vasculature.
  • Backbleed bores 38 of plunger 32 are in communication with backbleed lumens (not shown) within tubes 36. The backbleed lumens of tubes 36 are in communication with backbleed ports 32 of tines 17, thereby establishing a complete backbleed path through ports 32, the lumens (not shown) of tubes 36, and bores 38. When tines 17 of closure component 16 pierce a vessel wall surrounding a vascular puncture, blood enters backbleed ports 32 and exits through backbleed bores 38, providing visual confirmation to a surgeon that tines 17 are positioned within the vessel wall. The backbleed path thus enables the surgeon to determine when closure component 16 has been sufficiently advanced to permit rotation of component 16 to close the puncture, while reducing the risk that component 16 is either short of the puncture site or is extended into the vessel.
  • In conjunction with closure of the puncture site caused by rotation of component 16, a puncture sealant may be introduced to the puncture site to seal the site closed. The sealant may, for example, comprise an adhesive, such as a bioglue, tissue sealant, or clotting agent, delivered through hemostatic port 26, biocompatible tubing 28, side port 20 and central lumen 13 of introducer sheath 12 to the vascular puncture to further help seal the vessel after puncture closure with closure component 16. Alternatively, the adhesive may be delivered through device port 24 or through the backbleed path described above. Instead of adhesives, the closure component may further comprise the sealant, wherein the closure component is left in place within the vessel until hemostasis naturally occurs. The sealant may also comprise sutures delivered through central lumen 13. Additionally, the sealant may comprise thermal energy application from, for example, electrical induction, infrared light, ultrasonic vibration, microwave or laser irradiation, and other means.
  • With reference to FIG. 2, an alternative puncture sealing device in accordance with the present invention is described. Sealing device 50 comprises delivery device 52 and clip 54. Delivery device 52 comprises proximal end 56 attached to tube 58. Tube 58 terminates at first jaw 60 at its distal end and further comprises lumen 62 and pin 64. Pin 64 extends into lumen 62 from an interior surface of tube 58 and is disposed perpendicular to the longitudinal axis of tube 58.
  • Delivery device 52 further comprises second jaw 66 having female connector 68 coupled to pin 64, so that second jaw 66 pivots about pin 64. Second jaw 66 further comprises moment arm 70. Tension spring 72 is coupled to moment arm 70 and to the interior surface of tube 58 in a manner that biases second jaw 66 against first jaw 60.
  • First jaw 60 and second jaw 66 preferably form channel 74 when biased against one another. Channel 74 is configured to receive clip 54. The biasing force applied by tension spring 72 holds clip 54 within channel 74, so that the clip may be advanced into tissue surrounding a vascular puncture that has had its edges approximated by closure component 16 (FIG. 1).
  • Delivery device 52 still further comprises plunger 76 coupled to pushrod 78 having release arm 80. Pushrod 78 is received within lumen 62 of tube 58, so that release arm 80 engages moment arm 70.
  • Distal advancement of pushrod 78, via application of force to plunger 76, causes release arm 80 to urge moment arm 70 distally. This motion overcomes the biasing force applied by tension spring 72 and causes second jaw 66 to pivot about pin 64. Second jaw 66 thus no longer contacts first jaw 60, and clip 54 is released from channel 74. Tube 58, first jaw 60, second jaw 66, and clip 54 of sealing device 50 preferably are sized for introduction into a patient's vasculature through device bore 40, device port 24, and lumen 13 of vascular device 10.
  • Referring to FIGS. 3A-3D through 4A-4D, in conjunction with FIGS. 1 and 2, a method of using vascular device 10 with sealing device 50 is described. Sheath 12 is advanced through skin, fat, and muscle tissue into vessel V, through the vessel wall tissue surrounding vascular puncture P. With plunger 34 and tubes 36 of actuator 18 in the proximal-most, fully retracted position, an interventional procedure is performed by introducing one or more interventional devices, e.g. angioplasty balloons, stent delivery systems, atherectomy devices, etc., through device port 24 and lumen 13 of sheath 12, in accordance with well-known techniques. Side port 20 may be used to infuse fluids, e.g., contrast agents or medications, into the vessel through sheath 12 during the interventional procedure.
  • Upon completion of the procedure, vascular device 10 may be advantageously used to close vascular puncture P. At this point, closure actuator 18 and closure component 16 are disposed in the proximal-most position, with component 16 adjacent to hub 14. Closure actuator 18 is advanced by urging plunger 34 in the distal direction, thus causing tubes 36 to slide through arc lumens 22 of hub 14 and advance closure component 16.
  • As seen in FIG. 3A, continued distal advancement of plunger 34 causes tines 17 at the distal end of closure component 16 to pierce tissue surrounding puncture P, so that the backbleed ports 32 of tines 17 directly communicate with the puncture wound. Tine punctures T in FIG. 4A represent the points at which tines 17 enter vessel V. The presence of pressure in the vessel higher than atmospheric pressure causes blood to pass through backbleed ports 32, through the backbleed lumens (not shown) of tubes 36, and exit through the proximal ends of backbleed bores 38, thus confirming that tines 17 have engaged tissue around the puncture site and should not be advanced further.
  • In FIG. 3B, sheath 12 is removed from puncture P to facilitate closure of the puncture. Closure actuator 18 is held stationary while hub 14 is withdrawn proximally, thereby withdrawing sheath 12 proximally from puncture P. The puncture remains open, as seen in FIG. 4B. With sheath 12 no longer within puncture P, closure actuator 18 is rotated within arc lumens 22 to rotate closure component 16. Rotation of closure component 16 causes tines 17 to rotate and urge the puncture closed, as seen in FIGS. 3C and 4C.
  • Upon closure of puncture P, a sealant is introduced to seal the wound closed. The sealant may, for example, comprise an adhesive, such as a bioglue, tissue sealant, or clotting agent, it may comprise a suture, it may comprise thermal energy application, or it may comprise leaving the closure component in place within vessel V until hemostasis naturally occurs. Alternatively, the sealing device may comprise a clip, as described hereinafter.
  • FIGS. 3D and 4D show apparatus 10 used in conjunction with sealing device 50 of FIG. 2. With clip 54 disposed in channel 74 of delivery device 52, the delivery device is delivered to vessel V through device bore 40 of closure actuator 18, device port 24 of hub 14, and central lumen 13 of sheath 12. Clip 54 punctures the vessel at tissue surrounding closed puncture P, creating clip punctures C and sealing the puncture. Pushrod 78 of delivery device 52 is then actuated to separate second jaw 66 from first jaw 60 to release clip 54 from delivery device 52. Apparatus 10 and delivery device 52 are removed from the patient to complete the procedure. Clip 54 maintains closure until hemostasis occurs and is preferably bioabsorbable so that no foreign materials are permanently implanted in the patient's body. Additional clips may also be implanted, as required.
  • With reference now to FIGS. 5A-5C, an alternative integrated vascular device in accordance with the present invention is described. Apparatus 100 comprises sheath 102 coupled to hub 104, closure component 106, and closure actuator 108.
  • Like sheath 12, sheath 102 may, for example, comprise an introducer sheath, a trocar, or a catheter, and includes central lumen 103 through which other devices may be introduced into the vasculature, for example, to perform a diagnostic or interventional procedure such as angiography, angioplasty, or stenting, or to seal a puncture site. Hub 104 comprises bore 110, which slidably receives actuator 108, and device port 112, which is in communication with central lumen 103 of sheath 102 and permits introduction of interventional devices while preventing blood loss through central lumen 103. Hub 104 further comprises side port 114.
  • Closure component 106 comprises outer housing 116 having lumen 118 configured to slidably receive sheath 102, bore 120 for slidably receiving inner housing 122, lumen 124 adapted to receive closure actuator 108, and needles or prongs 126 with sharpened tips 128. Inner housing 122 has lumen 123 adapted to receive sheath 102 and channels 130 adapted to receive prongs 126. Component 106 comprises at least two prongs 126, and preferably comprises four.
  • Closure actuator 108 comprises actuation tube 132 having lumen 133, actuation rod 134 disposed within actuation tube 132, first plunger 136 coupled to the proximal end of tube 132, and second plunger 138 coupled to the proximal end of rod 134. The distal end of tube 132 is affixed, either permanently or detachably, in lumen 124 to outer housing 116 of closure component 106, while the distal end of rod 134 is coupled to inner housing 122.
  • To perform an interventional procedure through central lumen 103 of sheath 102, the sheath is advanced through skin, fat, and muscle tissue into vessel V, through vascular puncture P, in accordance with well-known techniques. With closure component 106 in the proximal-most, fully retracted position adjacent hub 104, the interventional procedure then is performed by introducing one or more interventional devices, e.g. angioplasty balloons, stent delivery systems, atherectomy devices, etc., through device port 112 and lumen 103 of sheath 102, again in accordance with well-known techniques. Side port 114 may be used to infuse fluids, e.g., contrast agents or medications, into the vessel through sheath 102 during the interventional procedure.
  • Upon completion of the procedure, apparatus 100 advantageously may be used to close the vessel. Closure component 106 is advanced distally by urging plungers 136 and 138 distally. Inner housing 122 is only partially received within bore 120 of outer housing 116 so that prongs 126 are elastically deformed and received within channels 130. As shown in FIG. 5A, closure component 106 is advanced until inner housing 122 abuts against the vessel V, as may be determined, for example, with a backbleed indicator (not shown).
  • In FIG. 5B, first plunger 136 is urged distally to distally advance actuation tube 132 and outer housing 116, while second plunger 138 and sheath 102 are held stationary. Advancement of outer housing 116 advances sharpened tips 128 of prongs 126 into tissue surrounding puncture P.
  • In FIG. 5C, sheath 102 and second plunger 138 are retracted proximally to draw sheath 102 out of vessel V and to draw inner housing 122 completely within bore 120 of outer housing 116. Proximally retracting inner housing 122 via actuation rod 134 and second plunger 138 removes prongs 126 of outer housing 116 from channels 130 of the inner housing. The prongs resiliently contract to a lower stress configuration, thereby drawing opposing sides of puncture P together and closing the wound. A sealant, for example clip 54 of FIG. 2, may then be introduced to the closed puncture to seal the site closed, as discussed hereinabove. Alternatively, the sealing device may comprise RF current, supplied by an RF generator (not shown), applied across opposed tips 128, which act as bipolar electrodes.
  • Referring to FIGS. 6A-6E, as well as FIGS. 7A and 7B, a still further alternative embodiment of apparatus of the present invention is described. FIG. 6 depict the closure component of an integrated vascular device in use at vascular puncture P within vessel V. Apparatus 150 comprises sheath 152 coupled to a hub (not shown), closure component 154, and a closure actuator (not shown). Various closure actuators for use with closure component 154 will be apparent to those of skill in the art from the foregoing embodiments.
  • Sheath 152 may, for example, comprise an introducer sheath, a trocar, or a catheter, and includes central lumen 153 through which other devices may be introduced into the vasculature, for example, to perform a diagnostic or interventional procedure such as angiography, angioplasty, or stenting, or to seal a puncture site. Closure component 154 comprises spacer 156, needles 158, and needle cover 160. Spacer 156 is coaxially and slidably disposed about the exterior of sheath 152, and preferably has an annular diameter of about 1 mm to ensure that needles 158 engage the tissue surrounding puncture P rather than enter the puncture, so that the needles are able to draw the wound closed, as described hereinbelow. Needles 158 are disposed between spacer 156 and cover 160 during advancement to puncture P. Needles 158 comprise ledges 162, which act as positive stops to prevent excessive advancement of the needles with respect to cover 160, which comprises corresponding annular ledge 164. Cover 160 further comprises elastic segment 166, configured to elastically deform needles 158. Closure component 154 comprises at least two needles 158, and preferably comprises four. Needles 158 may further comprise retaining means (not shown), such as barbs or hooks, to assist in gripping tissue.
  • As shown in FIG. 6A, sheath 152 may be advanced through skin, fat, and muscle tissue into vessel V, through vascular puncture P, in accordance with well-known techniques. With closure component 154 in a proximal-most, fully retracted position adjacent the hub, an interventional procedure is performed through central lumen 153 of sheath 152 by introducing one or more interventional devices through the lumen into the patient's vasculature. Closure component 154 then is advanced via the closure actuator until it abuts against vessel V, as may be determined, for example, with a backbleed indicator, such as described for the foregoing embodiments. Cover 160 protects needles 158 and prevents snagging of tissue as closure component 154 is distally advanced down sheath 152 and through skin, fat, and muscle tissue. Spacer 156 retains needles 158 in a position away from the edge of puncture P.
  • In FIG. 6B, needles 158 are distally advanced with respect to needle cover 160 until ledge 162 abuts ledge 164. Needles 158 deflect elastic segment 166 of cover 160 outward and pierce tissue surrounding puncture P. FIG. 7A depicts, in isometric view, the segment of vessel V surrounding puncture P. With a needle arrangement comprising four needles 158, the needles create needle punctures N surrounding vascular puncture P. Sheath 152 and spacer 156 then are retracted proximally and removed from vessel V, as shown in FIG. 6C. As depicted in FIGS. 6D and 7B, elastic segment 166 of needle cover 160 resiliently contracts, thereby drawing needles 158 together and approximating the edges of the wound.
  • A sealant, such as a bioglue, tissue sealant, or clotting agent, then may be introduced to the puncture site to seal the wound closed. Alternatively, closure component 154 may be maintained in position until hemostasis occurs naturally, or sutures may be introduced through central lumen 153. In addition, or in the alternative, RF energy may be applied across needles 158, as described hereinabove with respect to FIG. 5, or a clip, such as clip 54 of sealing device 50 of FIG. 2, may be applied. Thermal energy from electrical induction, infrared light, ultrasonic vibration, microwave or laser irradiation, and other means may also be used to seal the puncture.
  • Illustratively, FIG. 6E depicts sealing device 170, comprising adhesive 172, being delivered through central lumen 153 within delivery sheath 174. After sufficient time for adhesive 172 to set, apparatus 150 is removed from vessel V.
  • Although preferred illustrative embodiments of the present invention are described hereinabove, it will be evident to one skilled in the art that various changes and modifications may be made without departing from the invention. It is intended in the appended claims to cover all such changes and modifications that fall within the true spirit and scope of the invention.

Claims (20)

1. A method of closing an opening in tissue, comprising:
disposing a sheath within a tissue tract, wherein a distal end of the sheath is disposed within an opening formed in tissue;
performing a medical procedure through a lumen of the sheath;
closing the opening with a closure component, the closure component comprising at least two sharpened tips for engagement with tissue adjacent the opening, the sharpened tips having an expanded delivery configuration and a retracted deployed configuration to close the opening; and
applying a sealing means to the opening to effect closure of the opening.
2. The method according to claim 1, wherein the step of applying a sealing means comprises applying a sealing means selected from a group consisting of RF energy, thermal energy, electrical induction, infrared light, ultrasonic vibration, microwave or laser irradiation, clips, sutures, or adhesives.
3. The method according to claim 1, further comprising the step of delivering a sealant to the opening.
4. The method according to claim 1, further comprising the step of disposing a clip adjacent the opening to further seal the opening closed.
5. The method according to claim 1, wherein the closing step further comprises rotating the closure component after engaging the sharpened tips with the tissue.
6. The method according to claim 1, wherein the sharpened tips are associated with elastically deformed prongs.
7. The method according to claim 6, wherein the step of closing the opening further comprises moving a member within the closure component proximally to enable the elastically deformed needles to resiliently contract.
8. A method of closing an opening in tissue, comprising:
disposing a sheath within a tissue tract, wherein a distal end of the sheath is disposed within an opening formed in tissue;
performing a medical procedure through a lumen of the sheath;
positioning a closure component to close the opening, the closure component comprising at least two sharpened tips for engagement with tissue adjacent the opening, the sharpened tips having an expanded delivery configuration and a retracted deployed configuration;
closing the opening formed in the tissue; and
applying a sealing means to the opening to effect closure of the opening.
9. The method according to claim 8, wherein positioning the closure component comprises sliding the closure component along the sheath until the at least two sharpened tips engage with tissue.
10. The method according to claim 8, wherein closing the opening comprises moving a member within the closure component proximally to move the at least two sharpened tips towards one another.
11. The method according to claim 8, wherein closing the opening comprises rotating the closure component after engaging the at least two sharpened tips with the tissue.
12. A method of closing an opening in tissue, comprising:
disposing a sheath within a tissue tract, the sheath comprising a proximal end, a distal end disposable within an opening formed in tissue, and a lumen extending from the proximal end toward the distal end;
performing a medical procedure through the lumen of the sheath;
positioning a closure component upon the tissue adjacent to the opening, the closure component comprising at least two sharpened tips for engagement with tissue, the sharpened tips having an expanded delivery configuration and a retracted deployed configuration;
closing the opening formed in the tissue; and
applying a sealing means to the opening to effect closure of the opening.
13. The method according to claim 12, wherein applying the sealing means comprises:
disposing a sealing device, which supports a clip, through the lumen of the shaft;
deploying the clip from the sealing device to effect closure of the opening.
14. The method according to claim 13, wherein disposing the sealing device comprises moving the sealing device through the lumen until at least two sharpened tips of the clip contacts the tissue.
15. The method according to claim 13, further comprising delivering a sealant to the opening.
16. The method according to claim 13, wherein the sealing device comprises a first jaw and a second jaw pivotal relative to the first jaw, the first jaw and the second jaw selectively retaining the clip.
17. The method according to claim 15, wherein deploying the clip comprises moving the second jaw relative to the first jaw to release the clip.
18. The method according to claim 13, wherein closing the opening comprises moving a member within the closure component proximally to move the at least two sharpened tips towards one another.
19. The method according to claim 18, wherein the at least two sharpened tips are associated with elastically deformed needles, and wherein moving the member releases the elastically deformed needles and moves the at least two sharpened tips towards one another.
20. The method according to claim 13, wherein closing the opening comprises rotating the closure component after engaging the at least two sharpened tips with the tissue.
US11/344,868 2000-01-05 2006-02-01 Integrated vascular device with puncture site closure component and sealant and methods of use Abandoned US20060190037A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US09/478,179 US6197042B1 (en) 2000-01-05 2000-01-05 Vascular sheath with puncture site closure apparatus and methods of use
US10/147,774 US7931669B2 (en) 2000-01-05 2002-05-17 Integrated vascular device with puncture site closure component and sealant and methods of use
US11/344,868 US20060190037A1 (en) 2000-01-05 2006-02-01 Integrated vascular device with puncture site closure component and sealant and methods of use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/344,868 US20060190037A1 (en) 2000-01-05 2006-02-01 Integrated vascular device with puncture site closure component and sealant and methods of use

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US10/147,774 Division US7931669B2 (en) 2000-01-05 2002-05-17 Integrated vascular device with puncture site closure component and sealant and methods of use

Publications (1)

Publication Number Publication Date
US20060190037A1 true US20060190037A1 (en) 2006-08-24

Family

ID=23898839

Family Applications (5)

Application Number Title Priority Date Filing Date
US09/478,179 Active US6197042B1 (en) 2000-01-05 2000-01-05 Vascular sheath with puncture site closure apparatus and methods of use
US09/764,813 Active US6277140B2 (en) 2000-01-05 2001-01-16 Vascular sheath with puncture site closure apparatus and methods of use
US09/933,299 Active 2020-05-13 US6632238B2 (en) 2000-01-05 2001-08-20 Vascular sheath with puncture site closure apparatus and methods of use
US11/344,793 Abandoned US20060190014A1 (en) 2000-01-05 2006-01-31 Integrated vascular device with puncture site closure component and sealant and methods of use
US11/344,868 Abandoned US20060190037A1 (en) 2000-01-05 2006-02-01 Integrated vascular device with puncture site closure component and sealant and methods of use

Family Applications Before (4)

Application Number Title Priority Date Filing Date
US09/478,179 Active US6197042B1 (en) 2000-01-05 2000-01-05 Vascular sheath with puncture site closure apparatus and methods of use
US09/764,813 Active US6277140B2 (en) 2000-01-05 2001-01-16 Vascular sheath with puncture site closure apparatus and methods of use
US09/933,299 Active 2020-05-13 US6632238B2 (en) 2000-01-05 2001-08-20 Vascular sheath with puncture site closure apparatus and methods of use
US11/344,793 Abandoned US20060190014A1 (en) 2000-01-05 2006-01-31 Integrated vascular device with puncture site closure component and sealant and methods of use

Country Status (1)

Country Link
US (5) US6197042B1 (en)

Cited By (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050251183A1 (en) * 2002-09-13 2005-11-10 Damage Control Surgical Technologies, Inc. Method and apparatus for vascular and visceral clipping
USD611144S1 (en) 2006-06-28 2010-03-02 Abbott Laboratories Apparatus for delivering a closure element
US7806904B2 (en) 2000-12-07 2010-10-05 Integrated Vascular Systems, Inc. Closure device
US7819895B2 (en) 2000-01-05 2010-10-26 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US7828817B2 (en) 2000-01-05 2010-11-09 Integrated Vascular Systems, Inc. Apparatus and methods for delivering a closure device
US7841502B2 (en) 2007-12-18 2010-11-30 Abbott Laboratories Modular clip applier
US7842068B2 (en) 2000-12-07 2010-11-30 Integrated Vascular Systems, Inc. Apparatus and methods for providing tactile feedback while delivering a closure device
US7850709B2 (en) 2002-06-04 2010-12-14 Abbott Vascular Inc. Blood vessel closure clip and delivery device
US7854810B2 (en) 2002-12-31 2010-12-21 Integrated Vascular Systems, Inc. Methods for manufacturing a clip and clip
US7857828B2 (en) 2003-01-30 2010-12-28 Integrated Vascular Systems, Inc. Clip applier and methods of use
US7879071B2 (en) 2000-12-07 2011-02-01 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7887563B2 (en) 2001-06-07 2011-02-15 Abbott Vascular Inc. Surgical staple
US7905900B2 (en) 2003-01-30 2011-03-15 Integrated Vascular Systems, Inc. Clip applier and methods of use
US7931669B2 (en) 2000-01-05 2011-04-26 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US8007512B2 (en) 2002-02-21 2011-08-30 Integrated Vascular Systems, Inc. Plunger apparatus and methods for delivering a closure device
US20120109189A1 (en) * 2010-11-01 2012-05-03 Abbott Cardiovascular Systems, Inc. Methods and systems for establishing hemostasis relative to a puncture
US8202293B2 (en) 2003-01-30 2012-06-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8226681B2 (en) 2007-06-25 2012-07-24 Abbott Laboratories Methods, devices, and apparatus for managing access through tissue
US8398656B2 (en) 2003-01-30 2013-03-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8518063B2 (en) 2001-04-24 2013-08-27 Russell A. Houser Arteriotomy closure devices and techniques
US8518057B2 (en) 2005-07-01 2013-08-27 Abbott Laboratories Clip applier and methods of use
US8556930B2 (en) 2006-06-28 2013-10-15 Abbott Laboratories Vessel closure device
US8556932B2 (en) 2011-05-19 2013-10-15 Abbott Cardiovascular Systems, Inc. Collapsible plug for tissue closure
US8590760B2 (en) 2004-05-25 2013-11-26 Abbott Vascular Inc. Surgical stapler
US8603116B2 (en) 2010-08-04 2013-12-10 Abbott Cardiovascular Systems, Inc. Closure device with long tines
US8617184B2 (en) 2011-02-15 2013-12-31 Abbott Cardiovascular Systems, Inc. Vessel closure system
US20140052125A1 (en) * 2011-04-08 2014-02-20 Coviden Lp Flexible microwave catheters for natural or artificial lumens
US8657852B2 (en) 2008-10-30 2014-02-25 Abbott Vascular Inc. Closure device
US8672953B2 (en) 2007-12-17 2014-03-18 Abbott Laboratories Tissue closure system and methods of use
US8685047B2 (en) 2011-02-07 2014-04-01 Abbott Vascular, Inc. Scaffold device for preventing tissue trauma
US8690910B2 (en) 2000-12-07 2014-04-08 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8758398B2 (en) 2006-09-08 2014-06-24 Integrated Vascular Systems, Inc. Apparatus and method for delivering a closure element
US8758400B2 (en) 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Closure system and methods of use
US8758399B2 (en) 2010-08-02 2014-06-24 Abbott Cardiovascular Systems, Inc. Expandable bioabsorbable plug apparatus and method
US8784447B2 (en) 2000-09-08 2014-07-22 Abbott Vascular Inc. Surgical stapler
US8808310B2 (en) 2006-04-20 2014-08-19 Integrated Vascular Systems, Inc. Resettable clip applier and reset tools
US8821534B2 (en) 2010-12-06 2014-09-02 Integrated Vascular Systems, Inc. Clip applier having improved hemostasis and methods of use
US8858594B2 (en) 2008-12-22 2014-10-14 Abbott Laboratories Curved closure device
US8893947B2 (en) 2007-12-17 2014-11-25 Abbott Laboratories Clip applier and methods of use
US8920442B2 (en) 2005-08-24 2014-12-30 Abbott Vascular Inc. Vascular opening edge eversion methods and apparatuses
US8926633B2 (en) 2005-06-24 2015-01-06 Abbott Laboratories Apparatus and method for delivering a closure element
US8961541B2 (en) 2007-12-03 2015-02-24 Cardio Vascular Technologies Inc. Vascular closure devices, systems, and methods of use
US8992567B1 (en) 2001-04-24 2015-03-31 Cardiovascular Technologies Inc. Compressible, deformable, or deflectable tissue closure devices and method of manufacture
US9055932B2 (en) 2011-08-26 2015-06-16 Abbott Cardiovascular Systems, Inc. Suture fastener combination device
US9089674B2 (en) 2000-10-06 2015-07-28 Integrated Vascular Systems, Inc. Apparatus and methods for positioning a vascular sheath
US9089311B2 (en) 2009-01-09 2015-07-28 Abbott Vascular Inc. Vessel closure devices and methods
US9138214B2 (en) 2012-03-02 2015-09-22 Abbott Cardiovascular Systems, Inc. Suture securing systems, devices and methods
US9149276B2 (en) 2011-03-21 2015-10-06 Abbott Cardiovascular Systems, Inc. Clip and deployment apparatus for tissue closure
US9149265B2 (en) 2011-02-26 2015-10-06 Abbott Cardiovascular Systems, Inc. Hinged tissue support device
US9241706B2 (en) 2003-09-15 2016-01-26 Abbott Laboratories Suture locking device and methods
US9282965B2 (en) 2008-05-16 2016-03-15 Abbott Laboratories Apparatus and methods for engaging tissue
US9314230B2 (en) 2009-01-09 2016-04-19 Abbott Vascular Inc. Closure device with rapidly eroding anchor
US9332976B2 (en) 2011-11-30 2016-05-10 Abbott Cardiovascular Systems, Inc. Tissue closure device
US9345460B2 (en) 2001-04-24 2016-05-24 Cardiovascular Technologies, Inc. Tissue closure devices, device and systems for delivery, kits and methods therefor
US9364209B2 (en) 2012-12-21 2016-06-14 Abbott Cardiovascular Systems, Inc. Articulating suturing device
US9414824B2 (en) 2009-01-16 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US9486191B2 (en) 2009-01-09 2016-11-08 Abbott Vascular, Inc. Closure devices
US9579091B2 (en) 2000-01-05 2017-02-28 Integrated Vascular Systems, Inc. Closure system and methods of use
US9585647B2 (en) 2009-08-26 2017-03-07 Abbott Laboratories Medical device for repairing a fistula
US10143460B2 (en) 2013-01-17 2018-12-04 Abbott Cardiovascular Systems, Inc. Access device for accessing tissue
USD843573S1 (en) 2015-11-13 2019-03-19 Access Closure, Inc. Vascular closure apparatus
USD847988S1 (en) 2015-11-13 2019-05-07 Access Closure, Inc. Handle grip

Families Citing this family (401)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020095164A1 (en) * 1997-06-26 2002-07-18 Andreas Bernard H. Device and method for suturing tissue
US7029480B2 (en) * 2001-01-24 2006-04-18 Abott Laboratories Device and method for suturing of internal puncture sites
US6287322B1 (en) * 1995-12-07 2001-09-11 Loma Linda University Medical Center Tissue opening locator and everter and method
US7223273B2 (en) * 1996-07-23 2007-05-29 Tyco Healthcare Group Lp Anastomosis instrument and method for performing same
US6440146B2 (en) 1996-07-23 2002-08-27 United States Surgical Corporation Anastomosis instrument and method
US20020019642A1 (en) * 1996-07-23 2002-02-14 Keith Milliman Anastomosis instrument and method for performing same
US6726704B1 (en) 1998-05-29 2004-04-27 By-Pass, Inc. Advanced closure device
US7396359B1 (en) * 1998-05-29 2008-07-08 Bypass, Inc. Vascular port device
US20050283188A1 (en) * 1998-05-29 2005-12-22 By-Pass, Inc. Vascular closure device
AT410119T (en) 1998-12-01 2008-10-15 Univ Washington A device for intravascular embolization
US20040092964A1 (en) 1999-03-04 2004-05-13 Modesitt D. Bruce Articulating suturing device and method
US7235087B2 (en) * 1999-03-04 2007-06-26 Abbott Park Articulating suturing device and method
US6964668B2 (en) * 1999-03-04 2005-11-15 Abbott Laboratories Articulating suturing device and method
US7001400B1 (en) 1999-03-04 2006-02-21 Abbott Laboratories Articulating suturing device and method
US7267679B2 (en) * 1999-09-13 2007-09-11 Rex Medical, L.P Vascular hole closure device
US7341595B2 (en) 1999-09-13 2008-03-11 Rex Medical, L.P Vascular hole closure device
US7942888B2 (en) 1999-09-13 2011-05-17 Rex Medical, L.P. Vascular hole closure device
US7662161B2 (en) * 1999-09-13 2010-02-16 Rex Medical, L.P Vascular hole closure device
ES2283316T3 (en) * 1999-09-13 2007-11-01 Rex Medical, Lp vascular closure.
US8083766B2 (en) * 1999-09-13 2011-12-27 Rex Medical, Lp Septal defect closure device
US6475189B1 (en) * 1999-12-21 2002-11-05 Ethicon, Inc. Apparatus and method for a self-blunting safety catheter
US6780197B2 (en) * 2000-01-05 2004-08-24 Integrated Vascular Systems, Inc. Apparatus and methods for delivering a vascular closure device to a body lumen
US6197042B1 (en) * 2000-01-05 2001-03-06 Medical Technology Group, Inc. Vascular sheath with puncture site closure apparatus and methods of use
DE60127236T2 (en) * 2000-01-18 2007-11-22 Tyco Healthcare Group Lp, Norwalk Instrument for anastomosis
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US6440152B1 (en) 2000-07-28 2002-08-27 Microvena Corporation Defect occluder release assembly and method
US6890342B2 (en) 2000-08-02 2005-05-10 Loma Linda University Method and apparatus for closing vascular puncture using hemostatic material
US20040093024A1 (en) * 2000-09-01 2004-05-13 James Lousararian Advanced wound site management systems and methods
US6533762B2 (en) * 2000-09-01 2003-03-18 Angiolink Corporation Advanced wound site management systems and methods
US7074232B2 (en) * 2000-09-01 2006-07-11 Medtronic Angiolink, Inc. Advanced wound site management systems and methods
US8551134B2 (en) * 2000-09-01 2013-10-08 Medtronic Vascular, Inc. Wound site management and wound closure device
US6767356B2 (en) 2000-09-01 2004-07-27 Angiolink Corporation Advanced wound site management systems and methods
US6755842B2 (en) * 2000-09-01 2004-06-29 Angiolink Corporation Advanced wound site management systems and methods
US7241302B2 (en) * 2001-10-18 2007-07-10 Tyco Healthcare Group Lp Anastomosis instrument and method for performing same
US6719777B2 (en) * 2000-12-07 2004-04-13 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8083768B2 (en) * 2000-12-14 2011-12-27 Ensure Medical, Inc. Vascular plug having composite construction
US6846319B2 (en) * 2000-12-14 2005-01-25 Core Medical, Inc. Devices for sealing openings through tissue and apparatus and methods for delivering them
US6890343B2 (en) * 2000-12-14 2005-05-10 Ensure Medical, Inc. Plug with detachable guidewire element and methods for use
US6896692B2 (en) 2000-12-14 2005-05-24 Ensure Medical, Inc. Plug with collet and apparatus and method for delivering such plugs
US6623509B2 (en) * 2000-12-14 2003-09-23 Core Medical, Inc. Apparatus and methods for sealing vascular punctures
US6632237B2 (en) 2001-01-11 2003-10-14 Bio-Seal Tech, Inc. Device and method for sealing a puncture in a blood vessel
US20020099410A1 (en) * 2001-01-11 2002-07-25 Bio-Seal Tech Inc. Device and method for sealing a puncture in a blood vessel
ES2307723T3 (en) * 2001-01-24 2008-12-01 Tyco Healthcare Group Lp Instrumentio anastomosis and method for carrying it out.
US7025776B1 (en) 2001-04-24 2006-04-11 Advanced Catheter Engineering, Inc. Arteriotomy closure devices and techniques
US9861517B2 (en) * 2001-07-26 2018-01-09 Cook Medical Technologies Llc Vessel closure member, delivery apparatus, and method of inserting the member
US8465516B2 (en) * 2001-07-26 2013-06-18 Oregon Health Science University Bodily lumen closure apparatus and method
US7288105B2 (en) 2001-08-01 2007-10-30 Ev3 Endovascular, Inc. Tissue opening occluder
IES20010749A2 (en) * 2001-08-09 2003-02-19 Christy Cummins Surgical Stapling Device
IES20010748A2 (en) * 2001-08-09 2003-02-19 Christy Cummins Surgical Stapling Device and Method
US8409167B2 (en) 2004-07-19 2013-04-02 Broncus Medical Inc Devices for delivering substances through an extra-anatomic opening created in an airway
US20060025788A1 (en) * 2002-09-25 2006-02-02 By-Pass, Inc. Anastomotic leg arrangement
US7799042B2 (en) * 2004-05-13 2010-09-21 The Cleveland Clinic Foundation Skin lesion exciser and skin-closure device therefor
EP1450699A4 (en) * 2001-10-22 2007-05-30 Interventional Therapies Llc Removable sleeve
WO2003088846A1 (en) * 2002-04-22 2003-10-30 Tyco Healthcare Group, Lp Tack and tack applier
US7153286B2 (en) * 2002-05-24 2006-12-26 Baxter International Inc. Automated dialysis system
US6769594B2 (en) * 2002-05-31 2004-08-03 Tyco Healthcare Group, Lp End-to-end anastomosis instrument and method for performing same
US7195142B2 (en) * 2003-05-30 2007-03-27 Tyco Healthcare Group Lp End-to-end anastomosis instrument and method for performing same
WO2003105697A1 (en) 2002-06-14 2003-12-24 Loma Linda University Medical Center Vascular wound closure device and method
EP1646320B1 (en) * 2002-07-03 2009-02-25 Abbott Vascular Inc Surgical stapling device
US7108710B2 (en) 2002-11-26 2006-09-19 Abbott Laboratories Multi-element biased suture clip
AU2003297665A1 (en) * 2002-12-06 2004-06-30 Fast Country, Inc. Systems and methods for providing interactive guest resources
US7160309B2 (en) * 2002-12-31 2007-01-09 Laveille Kao Voss Systems for anchoring a medical device in a body lumen
US20040133218A1 (en) * 2003-01-07 2004-07-08 Charles Steven T. Wound clamp
EP1596723A2 (en) 2003-02-04 2005-11-23 ev3 Sunnyvale, Inc. Patent foramen ovale closure system
US20040176800A1 (en) * 2003-03-07 2004-09-09 Paraschac Joseph Francis Barbed closure device
EP1615540A4 (en) * 2003-04-22 2011-07-20 Sub Q Inc Puncture closure systeme with pin and pull technique
US9060770B2 (en) 2003-05-20 2015-06-23 Ethicon Endo-Surgery, Inc. Robotically-driven surgical instrument with E-beam driver
US20050010241A1 (en) * 2003-07-09 2005-01-13 Keith Milliman Anastomosis instrument and method for performing same
US8308682B2 (en) 2003-07-18 2012-11-13 Broncus Medical Inc. Devices for maintaining patency of surgically created channels in tissue
DE602004031953D1 (en) 2003-08-14 2011-05-05 Univ Loma Linda Med
US8137364B2 (en) 2003-09-11 2012-03-20 Abbott Laboratories Articulating suturing device and method
US7462188B2 (en) 2003-09-26 2008-12-09 Abbott Laboratories Device and method for suturing intracardiac defects
US7556647B2 (en) * 2003-10-08 2009-07-07 Arbor Surgical Technologies, Inc. Attachment device and methods of using the same
US8337522B2 (en) 2003-10-15 2012-12-25 St. Jude Medical Puerto Rico Llc Vascular sealing device with locking hub
US8852229B2 (en) * 2003-10-17 2014-10-07 Cordis Corporation Locator and closure device and method of use
US7361183B2 (en) 2003-10-17 2008-04-22 Ensure Medical, Inc. Locator and delivery device and method of use
US8128652B2 (en) * 2003-11-13 2012-03-06 St. Jude Medical Puerto Rico Llc Method and apparatus for sealing an internal tissue puncture incorporating a block and tackle
US20050107820A1 (en) * 2003-11-13 2005-05-19 Forsberg Andrew T. Vascular puncture depth locator
EP1696806B1 (en) * 2003-11-21 2012-08-29 Silk Road Medical, Inc. Apparatus for treating a carotid artery
US7621937B2 (en) 2003-12-03 2009-11-24 St. Jude Medical Puerto Rico LC Vascular sealing device with high surface area sealing plug
US7597705B2 (en) * 2003-12-03 2009-10-06 St. Jude Medical Puerto Rico Llc Vascular puncture seal anchor nest
US7449024B2 (en) 2003-12-23 2008-11-11 Abbott Laboratories Suturing device with split arm and method of suturing tissue
US20050251204A1 (en) * 2004-05-06 2005-11-10 Jurg Attinger Wound clamp
US20050267520A1 (en) 2004-05-12 2005-12-01 Modesitt D B Access and closure device and method
US20050267521A1 (en) * 2004-05-13 2005-12-01 St. Jude Medical Puerto Rico B.V. Collagen sponge for arterial sealing
US7637925B2 (en) * 2004-06-28 2009-12-29 Cardio Life Research S.A. Surgical staple
EP1611850A1 (en) * 2004-06-28 2006-01-04 Cardio Life Research S.A. Occlusion and tight punction device for an anatomical structure
US7678133B2 (en) 2004-07-10 2010-03-16 Arstasis, Inc. Biological tissue closure device and method
US8215531B2 (en) 2004-07-28 2012-07-10 Ethicon Endo-Surgery, Inc. Surgical stapling instrument having a medical substance dispenser
US20060058844A1 (en) * 2004-09-13 2006-03-16 St. Jude Medical Puerto Rico B.V. Vascular sealing device with locking system
US20060184199A1 (en) * 2005-02-14 2006-08-17 O'leary Shawn Apparatus and methods for reducing bleeding from a cannulation site
EP1855617A4 (en) * 2005-03-11 2013-10-23 Covidien Lp Absorbable surgical fasteners
US7458978B1 (en) 2005-03-28 2008-12-02 Cardica, Inc. Vascular closure system utilizing a staple
US7344544B2 (en) * 2005-03-28 2008-03-18 Cardica, Inc. Vascular closure system
US7618436B2 (en) * 2005-04-12 2009-11-17 St. Jude Medical Puerto Rico Llc Tissue puncture closure device with scroll gear transmission tamping system
ES2401442T3 (en) 2005-04-22 2013-04-19 Rex Medical, L.P. Closing device for left atrial appendage
US8088144B2 (en) * 2005-05-04 2012-01-03 Ensure Medical, Inc. Locator and closure device and method of use
US8926654B2 (en) 2005-05-04 2015-01-06 Cordis Corporation Locator and closure device and method of use
AU2006247355B2 (en) * 2005-05-12 2013-01-10 Arstasis, Inc. Access and closure device and method
DE202005009061U1 (en) * 2005-05-31 2006-10-12 Karl Storz Gmbh & Co. Kg Clip and Clip translators for closing blood vessels
US20100114124A1 (en) * 2005-08-03 2010-05-06 Brian Kelleher Method and apparatus for partioning an organ within the body
US8083754B2 (en) * 2005-08-08 2011-12-27 Abbott Laboratories Vascular suturing device with needle capture
US8267947B2 (en) 2005-08-08 2012-09-18 Abbott Laboratories Vascular suturing device
US7883517B2 (en) 2005-08-08 2011-02-08 Abbott Laboratories Vascular suturing device
US9456811B2 (en) 2005-08-24 2016-10-04 Abbott Vascular Inc. Vascular closure methods and apparatuses
US8758397B2 (en) * 2005-08-24 2014-06-24 Abbott Vascular Inc. Vascular closure methods and apparatuses
US20070060895A1 (en) * 2005-08-24 2007-03-15 Sibbitt Wilmer L Jr Vascular closure methods and apparatuses
US8800838B2 (en) 2005-08-31 2014-08-12 Ethicon Endo-Surgery, Inc. Robotically-controlled cable-based surgical end effectors
US7934630B2 (en) 2005-08-31 2011-05-03 Ethicon Endo-Surgery, Inc. Staple cartridges for forming staples having differing formed staple heights
US9237891B2 (en) 2005-08-31 2016-01-19 Ethicon Endo-Surgery, Inc. Robotically-controlled surgical stapling devices that produce formed staples having different lengths
US20070194082A1 (en) 2005-08-31 2007-08-23 Morgan Jerome R Surgical stapling device with anvil having staple forming pockets of varying depths
US7669746B2 (en) 2005-08-31 2010-03-02 Ethicon Endo-Surgery, Inc. Staple cartridges for forming staples having differing formed staple heights
US10159482B2 (en) 2005-08-31 2018-12-25 Ethicon Llc Fastener cartridge assembly comprising a fixed anvil and different staple heights
CN101495047B (en) 2005-10-05 2011-12-28 洛马林达大学医学中心 The vessel wound closure apparatus and method
US20070106300A1 (en) * 2005-11-08 2007-05-10 Alcon, Inc. Surgical probe
US20070106317A1 (en) 2005-11-09 2007-05-10 Shelton Frederick E Iv Hydraulically and electrically actuated articulation joints for surgical instruments
US20070142850A1 (en) * 2005-12-15 2007-06-21 David Fowler Compression anastomosis device
US8382794B2 (en) * 2006-01-04 2013-02-26 St. Jude Medical Puerto Rico Llc Balloon insertion apparatus and method of sealing a tissue puncture
US20120292367A1 (en) 2006-01-31 2012-11-22 Ethicon Endo-Surgery, Inc. Robotically-controlled end effector
US8820603B2 (en) 2006-01-31 2014-09-02 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of a surgical instrument
US9861359B2 (en) 2006-01-31 2018-01-09 Ethicon Llc Powered surgical instruments with firing system lockout arrangements
US7845537B2 (en) 2006-01-31 2010-12-07 Ethicon Endo-Surgery, Inc. Surgical instrument having recording capabilities
US8763879B2 (en) 2006-01-31 2014-07-01 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of surgical instrument
US8161977B2 (en) 2006-01-31 2012-04-24 Ethicon Endo-Surgery, Inc. Accessing data stored in a memory of a surgical instrument
US8186555B2 (en) 2006-01-31 2012-05-29 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting and fastening instrument with mechanical closure system
US20110290856A1 (en) 2006-01-31 2011-12-01 Ethicon Endo-Surgery, Inc. Robotically-controlled surgical instrument with force-feedback capabilities
US8708213B2 (en) 2006-01-31 2014-04-29 Ethicon Endo-Surgery, Inc. Surgical instrument having a feedback system
US7749249B2 (en) 2006-02-21 2010-07-06 Kardium Inc. Method and device for closing holes in tissue
US8992422B2 (en) 2006-03-23 2015-03-31 Ethicon Endo-Surgery, Inc. Robotically-controlled endoscopic accessory channel
US20070225562A1 (en) 2006-03-23 2007-09-27 Ethicon Endo-Surgery, Inc. Articulating endoscopic accessory channel
WO2008010856A1 (en) * 2006-03-25 2008-01-24 Aponos Medical Corp. Self closing tissue fastener
US20070270688A1 (en) 2006-05-19 2007-11-22 Daniel Gelbart Automatic atherectomy system
US8322455B2 (en) 2006-06-27 2012-12-04 Ethicon Endo-Surgery, Inc. Manually driven surgical cutting and fastening instrument
US10028783B2 (en) 2006-06-28 2018-07-24 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US9597063B2 (en) 2006-06-28 2017-03-21 Abbott Laboratories Expandable introducer sheath to preserve guidewire access
US8449605B2 (en) 2006-06-28 2013-05-28 Kardium Inc. Method for anchoring a mitral valve
US9119633B2 (en) 2006-06-28 2015-09-01 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US8920411B2 (en) 2006-06-28 2014-12-30 Kardium Inc. Apparatus and method for intra-cardiac mapping and ablation
US7837610B2 (en) 2006-08-02 2010-11-23 Kardium Inc. System for improving diastolic dysfunction
US7842048B2 (en) 2006-08-18 2010-11-30 Abbott Laboratories Articulating suture device and method
US20080097218A1 (en) * 2006-08-24 2008-04-24 Boston Scientific Scimed, Inc. Blood vessel puncture locating apparatus and method
US7875053B2 (en) * 2006-09-15 2011-01-25 Cardica, Inc. Apparatus and method for closure of patent foramen ovale
US7749248B2 (en) * 2006-09-18 2010-07-06 St. Jude Medical Puerto Rico Llc Flexible tamping device
US10130359B2 (en) 2006-09-29 2018-11-20 Ethicon Llc Method for forming a staple
US7665647B2 (en) 2006-09-29 2010-02-23 Ethicon Endo-Surgery, Inc. Surgical cutting and stapling device with closure apparatus for limiting maximum tissue compression force
US8652120B2 (en) 2007-01-10 2014-02-18 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between control unit and sensor transponders
US8459520B2 (en) 2007-01-10 2013-06-11 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between control unit and remote sensor
US8684253B2 (en) 2007-01-10 2014-04-01 Ethicon Endo-Surgery, Inc. Surgical instrument with wireless communication between a control unit of a robotic system and remote sensor
US20080169332A1 (en) 2007-01-11 2008-07-17 Shelton Frederick E Surgical stapling device with a curved cutting member
US7628306B2 (en) * 2007-01-24 2009-12-08 Medtronic Vascular, Inc. Low-profile vascular closure systems and methods of using same
US20080195135A1 (en) * 2007-02-12 2008-08-14 Alcon, Inc. Surgical Probe
US7473258B2 (en) * 2007-03-08 2009-01-06 Cardica, Inc. Surgical stapler
US7533790B1 (en) 2007-03-08 2009-05-19 Cardica, Inc. Surgical stapler
US8893946B2 (en) * 2007-03-28 2014-11-25 Ethicon Endo-Surgery, Inc. Laparoscopic tissue thickness and clamp load measuring devices
US8534528B2 (en) 2007-06-04 2013-09-17 Ethicon Endo-Surgery, Inc. Surgical instrument having a multiple rate directional switching mechanism
US7905380B2 (en) 2007-06-04 2011-03-15 Ethicon Endo-Surgery, Inc. Surgical instrument having a multiple rate directional switching mechanism
US7832408B2 (en) 2007-06-04 2010-11-16 Ethicon Endo-Surgery, Inc. Surgical instrument having a directional switching mechanism
US8931682B2 (en) 2007-06-04 2015-01-13 Ethicon Endo-Surgery, Inc. Robotically-controlled shaft based rotary drive systems for surgical instruments
WO2009002390A1 (en) 2007-06-08 2008-12-31 Thomas Hsu Devices and methods for closure of wounds
US8408439B2 (en) 2007-06-22 2013-04-02 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with an articulatable end effector
US8574244B2 (en) 2007-06-25 2013-11-05 Abbott Laboratories System for closing a puncture in a vessel wall
US7669747B2 (en) 2007-06-29 2010-03-02 Ethicon Endo-Surgery, Inc. Washer for use with a surgical stapling instrument
EP2166954A1 (en) * 2007-07-13 2010-03-31 Rex Medical, L.P. Vascular hole closure device
WO2009012473A2 (en) * 2007-07-18 2009-01-22 Silk Road Medical, Inc. Methods and systems for establishing retrograde carotid arterial blood flow
US8858490B2 (en) 2007-07-18 2014-10-14 Silk Road Medical, Inc. Systems and methods for treating a carotid artery
US8568445B2 (en) * 2007-08-21 2013-10-29 St. Jude Medical Puerto Rico Llc Extra-vascular sealing device and method
US8876861B2 (en) * 2007-09-12 2014-11-04 Transluminal Technologies, Inc. Closure device, deployment apparatus, and method of deploying a closure device
US9456816B2 (en) 2007-09-12 2016-10-04 Transluminal Technologies, Llc Closure device, deployment apparatus, and method of deploying a closure device
MX2010002827A (en) 2007-09-12 2010-08-31 Transluminal Technologies Llc Closure device, deployment apparatus, and method of deploying a closure device.
US20090093826A1 (en) * 2007-10-05 2009-04-09 Cardica, Inc. Patent Foramen Ovale Closure System
US20090105744A1 (en) * 2007-10-17 2009-04-23 Modesitt D Bruce Methods for forming tracts in tissue
US8906011B2 (en) 2007-11-16 2014-12-09 Kardium Inc. Medical device for use in bodily lumens, for example an atrium
US8556931B2 (en) * 2007-12-17 2013-10-15 Abbott Laboratories Methods for imaging a delivery system
US8333787B2 (en) 2007-12-31 2012-12-18 St. Jude Medical Puerto Rico Llc Vascular closure device having a flowable sealing material
US8840640B2 (en) 2007-12-31 2014-09-23 St. Jude Medical Puerto Rico Llc Vascular closure device having an improved plug
US9282953B2 (en) * 2007-12-31 2016-03-15 St. Jude Medical Puerto Rico Llc Systems and methods for locating and closing a tissue puncture
US8489172B2 (en) 2008-01-25 2013-07-16 Kardium Inc. Liposuction system
JP2011510796A (en) 2008-02-05 2011-04-07 シルク・ロード・メディカル・インコーポレイテッドSilk Road Medical, Inc. Interventional catheter system and method
US8459525B2 (en) 2008-02-14 2013-06-11 Ethicon Endo-Sugery, Inc. Motorized surgical cutting and fastening instrument having a magnetic drive train torque limiting device
US8636736B2 (en) 2008-02-14 2014-01-28 Ethicon Endo-Surgery, Inc. Motorized surgical cutting and fastening instrument
US8752749B2 (en) 2008-02-14 2014-06-17 Ethicon Endo-Surgery, Inc. Robotically-controlled disposable motor-driven loading unit
US8622274B2 (en) 2008-02-14 2014-01-07 Ethicon Endo-Surgery, Inc. Motorized cutting and fastening instrument having control circuit for optimizing battery usage
US8657174B2 (en) 2008-02-14 2014-02-25 Ethicon Endo-Surgery, Inc. Motorized surgical cutting and fastening instrument having handle based power source
US8584919B2 (en) 2008-02-14 2013-11-19 Ethicon Endo-Sugery, Inc. Surgical stapling apparatus with load-sensitive firing mechanism
US8758391B2 (en) 2008-02-14 2014-06-24 Ethicon Endo-Surgery, Inc. Interchangeable tools for surgical instruments
US9179912B2 (en) 2008-02-14 2015-11-10 Ethicon Endo-Surgery, Inc. Robotically-controlled motorized surgical cutting and fastening instrument
US7861906B2 (en) 2008-02-14 2011-01-04 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with articulatable components
US7793812B2 (en) 2008-02-14 2010-09-14 Ethicon Endo-Surgery, Inc. Disposable motor-driven loading unit for use with a surgical cutting and stapling apparatus
US7819298B2 (en) 2008-02-14 2010-10-26 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with control features operable with one hand
US7866527B2 (en) 2008-02-14 2011-01-11 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with interlockable firing system
JP5410110B2 (en) 2008-02-14 2014-02-05 エシコン・エンド−サージェリィ・インコーポレイテッドEthicon Endo−Surgery,Inc. The surgical cutting and fastening instrument with Rf electrode
US8070772B2 (en) 2008-02-15 2011-12-06 Rex Medical, L.P. Vascular hole closure device
US8920462B2 (en) 2008-02-15 2014-12-30 Rex Medical, L.P. Vascular hole closure device
US8920463B2 (en) 2008-02-15 2014-12-30 Rex Medical, L.P. Vascular hole closure device
US9226738B2 (en) 2008-02-15 2016-01-05 Rex Medical, L.P. Vascular hole closure delivery device
US8491629B2 (en) 2008-02-15 2013-07-23 Rex Medical Vascular hole closure delivery device
US9770245B2 (en) 2008-02-15 2017-09-26 Ethicon Llc Layer arrangements for surgical staple cartridges
US20110029013A1 (en) 2008-02-15 2011-02-03 Mcguckin James F Vascular Hole Closure Device
US20090228040A1 (en) * 2008-03-04 2009-09-10 Medtronic Vascular, Inc. Mechanism and Method for Closing an Arteriotomy
US20090242609A1 (en) * 2008-03-31 2009-10-01 Medtronic Vascular, Inc. Vascular Puncture Closure Staple With Tip Protection
US20090254121A1 (en) * 2008-04-02 2009-10-08 Cardica, Inc. Vascular Closure with Multi-Pronged Clip
US20090287304A1 (en) 2008-05-13 2009-11-19 Kardium Inc. Medical Device for Constricting Tissue or a Bodily Orifice, for example a mitral valve
AU2009274127A1 (en) * 2008-07-21 2010-01-28 Arstasis, Inc. Devices, methods, and kits for forming tracts in tissue
US20100016810A1 (en) * 2008-07-21 2010-01-21 Arstasis. Inc., Devices and methods for forming tracts in tissue
US9011467B2 (en) * 2008-08-13 2015-04-21 Silk Road Medical, Inc. Suture delivery device
US8574245B2 (en) 2008-08-13 2013-11-05 Silk Road Medical, Inc. Suture delivery device
AU2009288440B2 (en) 2008-08-26 2015-04-23 St Jude Medical, Inc. Device and sealing component for sealing punctures
US7905381B2 (en) 2008-09-19 2011-03-15 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with cutting member arrangement
US8210411B2 (en) 2008-09-23 2012-07-03 Ethicon Endo-Surgery, Inc. Motor-driven surgical cutting instrument
US9050083B2 (en) 2008-09-23 2015-06-09 Ethicon Endo-Surgery, Inc. Motorized surgical instrument
US9386983B2 (en) 2008-09-23 2016-07-12 Ethicon Endo-Surgery, Llc Robotically-controlled motorized surgical instrument
US9005230B2 (en) 2008-09-23 2015-04-14 Ethicon Endo-Surgery, Inc. Motorized surgical instrument
US8608045B2 (en) 2008-10-10 2013-12-17 Ethicon Endo-Sugery, Inc. Powered surgical cutting and stapling apparatus with manually retractable firing system
WO2010059200A1 (en) * 2008-11-18 2010-05-27 Denis Labombard Adapter for attaching devices to endoscopes
US8239004B2 (en) * 2008-12-17 2012-08-07 Abbott Laboratories Methods for imaging an implant site
US8323312B2 (en) 2008-12-22 2012-12-04 Abbott Laboratories Closure device
US9414820B2 (en) 2009-01-09 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US9173644B2 (en) 2009-01-09 2015-11-03 Abbott Vascular Inc. Closure devices, systems, and methods
US8414577B2 (en) 2009-02-05 2013-04-09 Ethicon Endo-Surgery, Inc. Surgical instruments and components for use in sterile environments
US8397971B2 (en) 2009-02-05 2013-03-19 Ethicon Endo-Surgery, Inc. Sterilizable surgical instrument
US8444036B2 (en) 2009-02-06 2013-05-21 Ethicon Endo-Surgery, Inc. Motor driven surgical fastener device with mechanisms for adjusting a tissue gap within the end effector
US20110006101A1 (en) 2009-02-06 2011-01-13 EthiconEndo-Surgery, Inc. Motor driven surgical fastener device with cutting member lockout arrangements
US8052914B2 (en) 2009-02-20 2011-11-08 Boston Scientific Scimed, Inc. Modified plug for arteriotomy closure
US8529598B2 (en) 2009-02-20 2013-09-10 Boston Scientific Scimed, Inc. Tissue puncture closure device
US8292918B2 (en) 2009-02-20 2012-10-23 Boston Scientific Scimed, Inc. Composite plug for arteriotomy closure and method of use
US8317824B2 (en) 2009-02-20 2012-11-27 Boston Scientific Scimed, Inc. Tissue puncture closure device
US8375553B2 (en) 2009-02-20 2013-02-19 Boston Scientific Scimed, Inc. Locking element for vascular closure device
US9913634B2 (en) 2009-02-20 2018-03-13 Boston Scientific Scimed, Inc. Locking element for vascular closure device
US8905937B2 (en) 2009-02-26 2014-12-09 Integrated Vascular Systems, Inc. Methods and apparatus for locating a surface of a body lumen
AU2010248821A1 (en) * 2009-05-15 2011-12-01 Arstasis, Inc. Devices, methods and kits for forming tracts in tissue
US20110034802A1 (en) * 2009-08-05 2011-02-10 Abbott Laboratories Systems, methods, and apparatus for imaging an implantable device and methods for manufacturing
US20110054502A1 (en) * 2009-08-27 2011-03-03 Md-Art, Inc. Method for closing an aperture in a patient's body
JP2013505114A (en) * 2009-09-22 2013-02-14 アルスタシス,インコーポレイテッドArstasis,Inc. Apparatus for forming a tube in tissue, methods, and kits
US20110082538A1 (en) 2009-10-01 2011-04-07 Jonathan Dahlgren Medical device, kit and method for constricting tissue or a bodily orifice, for example, a mitral valve
US10194904B2 (en) * 2009-10-08 2019-02-05 Covidien Lp Surgical staple and method of use
US8413872B2 (en) 2009-10-28 2013-04-09 Covidien Lp Surgical fastening apparatus
AU2010318704B2 (en) 2009-11-10 2015-07-09 Nuvasive, Inc. Method and apparatus for performing spinal surgery
US8636655B1 (en) 2010-01-19 2014-01-28 Ronald Childs Tissue retraction system and related methods
WO2011100547A2 (en) 2010-02-11 2011-08-18 Boston Scientific Scimed, Inc. Automatic vascular closure deployment devices and methods
US8303624B2 (en) 2010-03-15 2012-11-06 Abbott Cardiovascular Systems, Inc. Bioabsorbable plug
US9050066B2 (en) 2010-06-07 2015-06-09 Kardium Inc. Closing openings in anatomical tissue
US8663252B2 (en) 2010-09-01 2014-03-04 Abbott Cardiovascular Systems, Inc. Suturing devices and methods
US9370353B2 (en) 2010-09-01 2016-06-21 Abbott Cardiovascular Systems, Inc. Suturing devices and methods
US8597340B2 (en) 2010-09-17 2013-12-03 Boston Scientific Scimed, Inc. Torque mechanism actuated bioabsorbable vascular closure device
US9877720B2 (en) 2010-09-24 2018-01-30 Ethicon Llc Control features for articulating surgical device
US8733613B2 (en) 2010-09-29 2014-05-27 Ethicon Endo-Surgery, Inc. Staple cartridge
US9629814B2 (en) 2010-09-30 2017-04-25 Ethicon Endo-Surgery, Llc Tissue thickness compensator configured to redistribute compressive forces
US20120080498A1 (en) 2010-09-30 2012-04-05 Ethicon Endo-Surgery, Inc. Curved end effector for a stapling instrument
US8893949B2 (en) 2010-09-30 2014-11-25 Ethicon Endo-Surgery, Inc. Surgical stapler with floating anvil
US9386984B2 (en) 2013-02-08 2016-07-12 Ethicon Endo-Surgery, Llc Staple cartridge comprising a releasable cover
RU2606493C2 (en) 2011-04-29 2017-01-10 Этикон Эндо-Серджери, Инк. Staple cartridge, containing staples, located inside its compressible part
US9332974B2 (en) 2010-09-30 2016-05-10 Ethicon Endo-Surgery, Llc Layered tissue thickness compensator
US8840003B2 (en) 2010-09-30 2014-09-23 Ethicon Endo-Surgery, Inc. Surgical stapling instrument with compact articulation control arrangement
US9517063B2 (en) 2012-03-28 2016-12-13 Ethicon Endo-Surgery, Llc Movable member for use with a tissue thickness compensator
US9615826B2 (en) 2010-09-30 2017-04-11 Ethicon Endo-Surgery, Llc Multiple thickness implantable layers for surgical stapling devices
US9301753B2 (en) 2010-09-30 2016-04-05 Ethicon Endo-Surgery, Llc Expandable tissue thickness compensator
US8940002B2 (en) 2010-09-30 2015-01-27 Kardium Inc. Tissue anchor system
BR112013007717A2 (en) 2010-09-30 2016-08-09 Ethicon Endo Surgery Inc System fasteners which comprises a retaining matrix array and an alignment
JP6224070B2 (en) 2012-03-28 2017-11-01 エシコン・エンド−サージェリィ・インコーポレイテッドEthicon Endo−Surgery,Inc. Retainer assembly including a tissue thickness compensator
US9211120B2 (en) 2011-04-29 2015-12-15 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising a plurality of medicaments
US9386988B2 (en) 2010-09-30 2016-07-12 Ethicon End-Surgery, LLC Retainer assembly including a tissue thickness compensator
US9414838B2 (en) 2012-03-28 2016-08-16 Ethicon Endo-Surgery, Llc Tissue thickness compensator comprised of a plurality of materials
US9364233B2 (en) 2010-09-30 2016-06-14 Ethicon Endo-Surgery, Llc Tissue thickness compensators for circular surgical staplers
US9016542B2 (en) 2010-09-30 2015-04-28 Ethicon Endo-Surgery, Inc. Staple cartridge comprising compressible distortion resistant components
US9220501B2 (en) 2010-09-30 2015-12-29 Ethicon Endo-Surgery, Inc. Tissue thickness compensators
US9314246B2 (en) 2010-09-30 2016-04-19 Ethicon Endo-Surgery, Llc Tissue stapler having a thickness compensator incorporating an anti-inflammatory agent
US9433419B2 (en) 2010-09-30 2016-09-06 Ethicon Endo-Surgery, Inc. Tissue thickness compensator comprising a plurality of layers
US9839420B2 (en) 2010-09-30 2017-12-12 Ethicon Llc Tissue thickness compensator comprising at least one medicament
US9700317B2 (en) 2010-09-30 2017-07-11 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a releasable tissue thickness compensator
AU2011326525B2 (en) 2010-11-09 2015-06-18 Transluminal Technologies, Llc Specially designed magnesium-aluminum alloys and medical uses thereof in a hemodynamic environment
US8758402B2 (en) 2010-12-17 2014-06-24 Boston Scientific Scimed, Inc. Tissue puncture closure device
US9452016B2 (en) 2011-01-21 2016-09-27 Kardium Inc. Catheter system
CA2764494A1 (en) 2011-01-21 2012-07-21 Kardium Inc. Enhanced medical device for use in bodily cavities, for example an atrium
US9480525B2 (en) 2011-01-21 2016-11-01 Kardium, Inc. High-density electrode-based medical device system
USD777925S1 (en) 2012-01-20 2017-01-31 Kardium Inc. Intra-cardiac procedure device
USD777926S1 (en) 2012-01-20 2017-01-31 Kardium Inc. Intra-cardiac procedure device
US9072511B2 (en) 2011-03-25 2015-07-07 Kardium Inc. Medical kit for constricting tissue or a bodily orifice, for example, a mitral valve
US9198662B2 (en) 2012-03-28 2015-12-01 Ethicon Endo-Surgery, Inc. Tissue thickness compensator having improved visibility
US9307972B2 (en) 2011-05-10 2016-04-12 Nuvasive, Inc. Method and apparatus for performing spinal fusion surgery
WO2012158553A2 (en) 2011-05-13 2012-11-22 Broncus Technologies, Inc. Methods and devices for excision of tissue
US8709034B2 (en) 2011-05-13 2014-04-29 Broncus Medical Inc. Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall
US9414822B2 (en) 2011-05-19 2016-08-16 Abbott Cardiovascular Systems, Inc. Tissue eversion apparatus and tissue closure device and methods for use thereof
US9072535B2 (en) 2011-05-27 2015-07-07 Ethicon Endo-Surgery, Inc. Surgical stapling instruments with rotatable staple deployment arrangements
US9549715B2 (en) 2011-08-09 2017-01-24 Cook Regentec Llc Vial useable in tissue extraction procedures
US9050084B2 (en) 2011-09-23 2015-06-09 Ethicon Endo-Surgery, Inc. Staple cartridge including collapsible deck arrangement
FR2982142B1 (en) * 2011-11-07 2013-11-29 Synchro Medical Clip for osteosynthesis
WO2013078235A1 (en) 2011-11-23 2013-05-30 Broncus Medical Inc Methods and devices for diagnosing, monitoring, or treating medical conditions through an opening through an airway wall
US9044230B2 (en) 2012-02-13 2015-06-02 Ethicon Endo-Surgery, Inc. Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status
RU2639857C2 (en) 2012-03-28 2017-12-22 Этикон Эндо-Серджери, Инк. Tissue thickness compensator containing capsule for medium with low pressure
US9307989B2 (en) 2012-03-28 2016-04-12 Ethicon Endo-Surgery, Llc Tissue stapler having a thickness compensator incorportating a hydrophobic agent
US8858573B2 (en) 2012-04-10 2014-10-14 Abbott Cardiovascular Systems, Inc. Apparatus and method for suturing body lumens
US8864778B2 (en) 2012-04-10 2014-10-21 Abbott Cardiovascular Systems, Inc. Apparatus and method for suturing body lumens
US9198592B2 (en) 2012-05-21 2015-12-01 Kardium Inc. Systems and methods for activating transducers
US9011423B2 (en) 2012-05-21 2015-04-21 Kardium, Inc. Systems and methods for selecting, activating, or selecting and activating transducers
US9241707B2 (en) 2012-05-31 2016-01-26 Abbott Cardiovascular Systems, Inc. Systems, methods, and devices for closing holes in body lumens
US9101358B2 (en) 2012-06-15 2015-08-11 Ethicon Endo-Surgery, Inc. Articulatable surgical instrument comprising a firing drive
US9282974B2 (en) 2012-06-28 2016-03-15 Ethicon Endo-Surgery, Llc Empty clip cartridge lockout
US9028494B2 (en) 2012-06-28 2015-05-12 Ethicon Endo-Surgery, Inc. Interchangeable end effector coupling arrangement
US9125662B2 (en) 2012-06-28 2015-09-08 Ethicon Endo-Surgery, Inc. Multi-axis articulating and rotating surgical tools
US9408606B2 (en) 2012-06-28 2016-08-09 Ethicon Endo-Surgery, Llc Robotically powered surgical device with manually-actuatable reversing system
US9289256B2 (en) 2012-06-28 2016-03-22 Ethicon Endo-Surgery, Llc Surgical end effectors having angled tissue-contacting surfaces
US20140005678A1 (en) 2012-06-28 2014-01-02 Ethicon Endo-Surgery, Inc. Rotary drive arrangements for surgical instruments
US8747238B2 (en) 2012-06-28 2014-06-10 Ethicon Endo-Surgery, Inc. Rotary drive shaft assemblies for surgical instruments with articulatable end effectors
US9561038B2 (en) 2012-06-28 2017-02-07 Ethicon Endo-Surgery, Llc Interchangeable clip applier
US9204879B2 (en) 2012-06-28 2015-12-08 Ethicon Endo-Surgery, Inc. Flexible drive member
US9364230B2 (en) 2012-06-28 2016-06-14 Ethicon Endo-Surgery, Llc Surgical stapling instruments with rotary joint assemblies
US9119657B2 (en) 2012-06-28 2015-09-01 Ethicon Endo-Surgery, Inc. Rotary actuatable closure arrangement for surgical end effector
US9226751B2 (en) 2012-06-28 2016-01-05 Ethicon Endo-Surgery, Inc. Surgical instrument system including replaceable end effectors
US9072536B2 (en) 2012-06-28 2015-07-07 Ethicon Endo-Surgery, Inc. Differential locking arrangements for rotary powered surgical instruments
US9101385B2 (en) 2012-06-28 2015-08-11 Ethicon Endo-Surgery, Inc. Electrode connections for rotary driven surgical tools
US10159479B2 (en) 2012-08-09 2018-12-25 Silk Road Medical, Inc. Suture delivery device
US9138215B2 (en) 2013-01-21 2015-09-22 Vi Bravoseal, Llc Vessel sealing device
US9131931B2 (en) 2013-01-21 2015-09-15 Vi Bravoseal, Llc Vessel sealing device with automatic deployment
US10307145B2 (en) 2013-01-21 2019-06-04 Cyndrx, Llc Vessel sealing device
US10092292B2 (en) 2013-02-28 2018-10-09 Ethicon Llc Staple forming features for surgical stapling instrument
US20140249557A1 (en) 2013-03-01 2014-09-04 Ethicon Endo-Surgery, Inc. Thumbwheel switch arrangements for surgical instruments
BR112015021098A2 (en) 2013-03-01 2017-07-18 Ethicon Endo Surgery Inc articulated surgical instruments with conductive pathways to sign communication
US20140263552A1 (en) 2013-03-13 2014-09-18 Ethicon Endo-Surgery, Inc. Staple cartridge tissue thickness sensor system
US9629629B2 (en) 2013-03-14 2017-04-25 Ethicon Endo-Surgey, LLC Control systems for surgical instruments
US9629623B2 (en) 2013-03-14 2017-04-25 Ethicon Endo-Surgery, Llc Drive system lockout arrangements for modular surgical instruments
US9351726B2 (en) 2013-03-14 2016-05-31 Ethicon Endo-Surgery, Llc Articulation control system for articulatable surgical instruments
US9572577B2 (en) 2013-03-27 2017-02-21 Ethicon Endo-Surgery, Llc Fastener cartridge comprising a tissue thickness compensator including openings therein
US9332984B2 (en) 2013-03-27 2016-05-10 Ethicon Endo-Surgery, Llc Fastener cartridge assemblies
US9795384B2 (en) 2013-03-27 2017-10-24 Ethicon Llc Fastener cartridge comprising a tissue thickness compensator and a gap setting element
US9801626B2 (en) 2013-04-16 2017-10-31 Ethicon Llc Modular motor driven surgical instruments with alignment features for aligning rotary drive shafts with surgical end effector shafts
US9574644B2 (en) 2013-05-30 2017-02-21 Ethicon Endo-Surgery, Llc Power module for use with a surgical instrument
US9987006B2 (en) 2013-08-23 2018-06-05 Ethicon Llc Shroud retention arrangement for sterilizable surgical instruments
US9301746B2 (en) 2013-10-11 2016-04-05 Abbott Cardiovascular Systems, Inc. Suture-based closure with hemostatic tract plug
US9681870B2 (en) 2013-12-23 2017-06-20 Ethicon Llc Articulatable surgical instruments with separate and distinct closing and firing systems
US20150173749A1 (en) 2013-12-23 2015-06-25 Ethicon Endo-Surgery, Inc. Surgical staples and staple cartridges
US9724092B2 (en) 2013-12-23 2017-08-08 Ethicon Llc Modular surgical instruments
US9839428B2 (en) 2013-12-23 2017-12-12 Ethicon Llc Surgical cutting and stapling instruments with independent jaw control features
US9642620B2 (en) 2013-12-23 2017-05-09 Ethicon Endo-Surgery, Llc Surgical cutting and stapling instruments with articulatable end effectors
US9962161B2 (en) 2014-02-12 2018-05-08 Ethicon Llc Deliverable surgical instrument
US9757124B2 (en) 2014-02-24 2017-09-12 Ethicon Llc Implantable layer assemblies
US9913642B2 (en) 2014-03-26 2018-03-13 Ethicon Llc Surgical instrument comprising a sensor system
US10004497B2 (en) 2014-03-26 2018-06-26 Ethicon Llc Interface systems for use with surgical instruments
US10013049B2 (en) 2014-03-26 2018-07-03 Ethicon Llc Power management through sleep options of segmented circuit and wake up control
US10028761B2 (en) 2014-03-26 2018-07-24 Ethicon Llc Feedback algorithms for manual bailout systems for surgical instruments
US9844369B2 (en) 2014-04-16 2017-12-19 Ethicon Llc Surgical end effectors with firing element monitoring arrangements
US10154904B2 (en) * 2014-04-28 2018-12-18 Edwards Lifesciences Corporation Intravascular introducer devices
US10182801B2 (en) 2014-05-16 2019-01-22 Silk Road Medical, Inc. Vessel access and closure assist system and method
US10045781B2 (en) 2014-06-13 2018-08-14 Ethicon Llc Closure lockout systems for surgical instruments
GB2543468A (en) 2014-08-13 2017-04-19 Nuvasive Inc Minimally disruptive retractor and associated methods for spinal surgery
US10016199B2 (en) 2014-09-05 2018-07-10 Ethicon Llc Polarity of hall magnet to identify cartridge type
US9801627B2 (en) 2014-09-26 2017-10-31 Ethicon Llc Fastener cartridge for creating a flexible staple line
US9801628B2 (en) 2014-09-26 2017-10-31 Ethicon Llc Surgical staple and driver arrangements for staple cartridges
US10076325B2 (en) 2014-10-13 2018-09-18 Ethicon Llc Surgical stapling apparatus comprising a tissue stop
US9924944B2 (en) 2014-10-16 2018-03-27 Ethicon Llc Staple cartridge comprising an adjunct material
US9844376B2 (en) 2014-11-06 2017-12-19 Ethicon Llc Staple cartridge comprising a releasable adjunct material
US10368936B2 (en) 2014-11-17 2019-08-06 Kardium Inc. Systems and methods for selecting, activating, or selecting and activating transducers
US10085748B2 (en) 2014-12-18 2018-10-02 Ethicon Llc Locking arrangements for detachable shaft assemblies with articulatable surgical end effectors
US9943309B2 (en) 2014-12-18 2018-04-17 Ethicon Llc Surgical instruments with articulatable end effectors and movable firing beam support arrangements
US9844375B2 (en) 2014-12-18 2017-12-19 Ethicon Llc Drive arrangements for articulatable surgical instruments
US10117649B2 (en) 2014-12-18 2018-11-06 Ethicon Llc Surgical instrument assembly comprising a lockable articulation system
US9987000B2 (en) 2014-12-18 2018-06-05 Ethicon Llc Surgical instrument assembly comprising a flexible articulation system
US9844374B2 (en) 2014-12-18 2017-12-19 Ethicon Llc Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member
US10188385B2 (en) 2014-12-18 2019-01-29 Ethicon Llc Surgical instrument system comprising lockable systems
US10226250B2 (en) 2015-02-27 2019-03-12 Ethicon Llc Modular stapling assembly
US10321907B2 (en) 2015-02-27 2019-06-18 Ethicon Llc System for monitoring whether a surgical instrument needs to be serviced
US10180463B2 (en) 2015-02-27 2019-01-15 Ethicon Llc Surgical apparatus configured to assess whether a performance parameter of the surgical apparatus is within an acceptable performance band
US10245033B2 (en) 2015-03-06 2019-04-02 Ethicon Llc Surgical instrument comprising a lockable battery housing
US10045776B2 (en) 2015-03-06 2018-08-14 Ethicon Llc Control techniques and sub-processor contained within modular shaft with select control processing from handle
US10052044B2 (en) 2015-03-06 2018-08-21 Ethicon Llc Time dependent evaluation of sensor data to determine stability, creep, and viscoelastic elements of measures
US9901342B2 (en) 2015-03-06 2018-02-27 Ethicon Endo-Surgery, Llc Signal and power communication system positioned on a rotatable shaft
US9895148B2 (en) 2015-03-06 2018-02-20 Ethicon Endo-Surgery, Llc Monitoring speed control and precision incrementing of motor for powered surgical instruments
US9808246B2 (en) 2015-03-06 2017-11-07 Ethicon Endo-Surgery, Llc Method of operating a powered surgical instrument
US9924961B2 (en) 2015-03-06 2018-03-27 Ethicon Endo-Surgery, Llc Interactive feedback system for powered surgical instruments
US9993248B2 (en) 2015-03-06 2018-06-12 Ethicon Endo-Surgery, Llc Smart sensors with local signal processing
US20160287250A1 (en) 2015-03-31 2016-10-06 Ethicon Endo-Surgery, Llc Surgical instrument with progressive rotary drive systems
US10368861B2 (en) 2015-06-18 2019-08-06 Ethicon Llc Dual articulation drive system arrangements for articulatable surgical instruments
US20170056000A1 (en) 2015-08-26 2017-03-02 Ethicon Endo-Surgery, Llc Surgical stapling configurations for curved and circular stapling instruments
US10172619B2 (en) 2015-09-02 2019-01-08 Ethicon Llc Surgical staple driver arrays
US10076326B2 (en) 2015-09-23 2018-09-18 Ethicon Llc Surgical stapler having current mirror-based motor control
US10327769B2 (en) 2015-09-23 2019-06-25 Ethicon Llc Surgical stapler having motor control based on a drive system component
US10085751B2 (en) 2015-09-23 2018-10-02 Ethicon Llc Surgical stapler having temperature-based motor control
US10105139B2 (en) 2015-09-23 2018-10-23 Ethicon Llc Surgical stapler having downstream current-based motor control
US10363036B2 (en) 2015-09-23 2019-07-30 Ethicon Llc Surgical stapler having force-based motor control
US10238386B2 (en) 2015-09-23 2019-03-26 Ethicon Llc Surgical stapler having motor control based on an electrical parameter related to a motor current
US10299878B2 (en) 2015-09-25 2019-05-28 Ethicon Llc Implantable adjunct systems for determining adjunct skew
US20170086832A1 (en) 2015-09-30 2017-03-30 Ethicon Endo-Surgery, Llc Tubular absorbable constructs
US10292704B2 (en) 2015-12-30 2019-05-21 Ethicon Llc Mechanisms for compensating for battery pack failure in powered surgical instruments
US10265068B2 (en) 2015-12-30 2019-04-23 Ethicon Llc Surgical instruments with separable motors and motor control circuits
US10368865B2 (en) 2015-12-30 2019-08-06 Ethicon Llc Mechanisms for compensating for drivetrain failure in powered surgical instruments
US20170224335A1 (en) 2016-02-09 2017-08-10 Ethicon Endo-Surgery, Llc Articulatable surgical instruments with off-axis firing beam arrangements
US10258331B2 (en) 2016-02-12 2019-04-16 Ethicon Llc Mechanisms for compensating for drivetrain failure in powered surgical instruments
US10357247B2 (en) 2016-04-15 2019-07-23 Ethicon Llc Surgical instrument with multiple program responses during a firing motion
US10335145B2 (en) 2016-04-15 2019-07-02 Ethicon Llc Modular surgical instrument with configurable operating mode
US20170296191A1 (en) 2016-04-18 2017-10-19 Ethicon Endo-Surgery, Llc Surgical instrument comprising a replaceable cartridge jaw
USD850617S1 (en) 2016-06-24 2019-06-04 Ethicon Llc Surgical fastener cartridge
USD847989S1 (en) 2016-06-24 2019-05-07 Ethicon Llc Surgical fastener cartridge
USD826405S1 (en) 2016-06-24 2018-08-21 Ethicon Llc Surgical fastener
USD822206S1 (en) 2016-06-24 2018-07-03 Ethicon Llc Surgical fastener
US10307170B2 (en) 2017-06-20 2019-06-04 Ethicon Llc Method for closed loop control of motor velocity of a surgical stapling and cutting instrument
US10327767B2 (en) 2017-06-20 2019-06-25 Ethicon Llc Control of motor velocity of a surgical stapling and cutting instrument based on angle of articulation
US10368864B2 (en) 2017-06-20 2019-08-06 Ethicon Llc Systems and methods for controlling displaying motor velocity for a surgical instrument
USD854151S1 (en) 2017-06-28 2019-07-16 Ethicon Llc Surgical instrument shaft
US10211586B2 (en) 2017-06-28 2019-02-19 Ethicon Llc Surgical shaft assemblies with watertight housings
USD851762S1 (en) 2017-06-28 2019-06-18 Ethicon Llc Anvil
US10258418B2 (en) 2017-06-29 2019-04-16 Ethicon Llc System for controlling articulation forces

Citations (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2583625A (en) * 1946-10-29 1952-01-29 Thomas & Betts Corp Method of and tool for crimping tubes
US3120230A (en) * 1960-10-24 1964-02-04 Jack H Sanders Surgical clamp
US3523351A (en) * 1967-10-20 1970-08-11 Sargent & Co Locator and holder in a crimping tool for an electrical connector
US3586002A (en) * 1968-01-08 1971-06-22 Ernest C Wood Surgical skin clip
US3677243A (en) * 1971-09-24 1972-07-18 Extracorporeal Med Spec Separable surgical needle
US3805337A (en) * 1973-04-23 1974-04-23 Raymond Lee Organization Inc Spring wire hose clamp
US3828791A (en) * 1973-03-21 1974-08-13 M Santos Surgical instruments
US4192315A (en) * 1976-12-23 1980-03-11 Aesculap-Werke Aktiengesellschaft Vormals Jetter & Scheerer Clip for surgical purposes
US4201215A (en) * 1977-09-06 1980-05-06 Crossett E S Apparatus and method for closing a severed sternum
US4217902A (en) * 1977-05-02 1980-08-19 March Alfred L Hemostatic clip
US4327485A (en) * 1980-05-21 1982-05-04 Amp Incorporated Pistol grip tool
US4345606A (en) * 1977-12-13 1982-08-24 Littleford Philip O Split sleeve introducers for pacemaker electrodes and the like
US4396139A (en) * 1980-02-15 1983-08-02 Technalytics, Inc. Surgical stapling system, apparatus and staple
US4440170A (en) * 1979-03-06 1984-04-03 Ethicon, Inc. Surgical clip applying instrument
US4505274A (en) * 1980-10-17 1985-03-19 Propper Manufacturing Co., Inc. Suture clip
USRE31855E (en) * 1978-12-01 1985-03-26 Cook, Inc. Tear apart cannula
US4586503A (en) * 1983-12-01 1986-05-06 University Of New Mexico Surgical microclip
US4635635A (en) * 1984-11-29 1987-01-13 Aspen Laboratories, Inc. Tourniquet cuff
US4687469A (en) * 1984-06-01 1987-08-18 Peter Osypka Device for slitting introducers for pacemaker electrodes
US4759364A (en) * 1985-09-19 1988-07-26 Richard Wolf Gmbh Pincers attachment for a surgical handle to be used in endoscopy
US4860746A (en) * 1982-04-20 1989-08-29 Inbae Yoon Elastic surgical ring clip and ring loader
US4917087A (en) * 1984-04-10 1990-04-17 Walsh Manufacturing (Mississuaga) Limited Anastomosis devices, kits and method
US4950258A (en) * 1988-01-28 1990-08-21 Japan Medical Supply Co., Ltd. Plastic molded articles with shape memory property
US5007921A (en) * 1989-10-26 1991-04-16 Brown Alan W Surgical staple
US5026390A (en) * 1989-10-26 1991-06-25 Brown Alan W Surgical staple
US5032127A (en) * 1990-03-07 1991-07-16 Frazee John G Hemostatic clip and applicator therefor
US5078731A (en) * 1990-06-05 1992-01-07 Hayhurst John O Suture clip
US5100418A (en) * 1987-05-14 1992-03-31 Inbae Yoon Suture tie device system and applicator therefor
US5108420A (en) * 1991-02-01 1992-04-28 Temple University Aperture occlusion device
US5116349A (en) * 1990-05-23 1992-05-26 United States Surgical Corporation Surgical fastener apparatus
US5176648A (en) * 1991-12-13 1993-01-05 Unisurge, Inc. Introducer assembly and instrument for use therewith
US5192302A (en) * 1989-12-04 1993-03-09 Kensey Nash Corporation Plug devices for sealing punctures and methods of use
US5192288A (en) * 1992-05-26 1993-03-09 Origin Medsystems, Inc. Surgical clip applier
US5222974A (en) * 1991-11-08 1993-06-29 Kensey Nash Corporation Hemostatic puncture closure system and method of use
US5275616A (en) * 1990-10-01 1994-01-04 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5304184A (en) * 1992-10-19 1994-04-19 Indiana University Foundation Apparatus and method for positive closure of an internal tissue membrane opening
US5318542A (en) * 1992-01-08 1994-06-07 Suddeutsche Feinmechanik Gmbh Split cannula and process for the production thereof
US5334217A (en) * 1992-01-21 1994-08-02 Regents Of The University Of Minnesota Septal defect closure device
US5340360A (en) * 1992-03-06 1994-08-23 Ethicon, Inc. Ligating clip applier
US5392978A (en) * 1991-02-08 1995-02-28 United States Surgical Corporation Surgical staple and endoscopic stapler
US5413584A (en) * 1992-05-11 1995-05-09 Ethicon, Inc. "Omega"-shaped staple for surgical, especially endoscopic, purposes
US5423857A (en) * 1993-11-02 1995-06-13 Ethicon, Inc. Three piece surgical staple
US5425489A (en) * 1990-12-20 1995-06-20 United States Surgical Corporation Fascia clip and instrument
US5431667A (en) * 1992-05-26 1995-07-11 Origin Medsystems, Inc. Gas-sealed instruments for use in laparoscopic surgery
US5507755A (en) * 1993-08-03 1996-04-16 Origin Medsystems, Inc. Apparatus and method for closing puncture wounds
US5527322A (en) * 1993-11-08 1996-06-18 Perclose, Inc. Device and method for suturing of internal puncture sites
US5728114A (en) * 1994-08-24 1998-03-17 Kensey Nash Corporation Apparatus and methods of use for preventing blood seepage at a percutaneous puncture site
US5782861A (en) * 1996-12-23 1998-07-21 Sub Q Inc. Percutaneous hemostasis device
US5782860A (en) * 1997-02-11 1998-07-21 Biointerventional Corporation Closure device for percutaneous occlusion of puncture sites and tracts in the human body and method
US5782844A (en) * 1996-03-05 1998-07-21 Inbae Yoon Suture spring device applicator
US5879366A (en) * 1996-12-20 1999-03-09 W.L. Gore & Associates, Inc. Self-expanding defect closure device and method of making and using
US5904697A (en) * 1995-02-24 1999-05-18 Heartport, Inc. Devices and methods for performing a vascular anastomosis
US5910155A (en) * 1998-06-05 1999-06-08 United States Surgical Corporation Vascular wound closure system
US5935147A (en) * 1991-11-08 1999-08-10 Kensey Nash Corporation Hemostatic puncture closure system and method of use
US6030364A (en) * 1997-10-03 2000-02-29 Boston Scientific Corporation Apparatus and method for percutaneous placement of gastro-intestinal tubes
US6036720A (en) * 1997-12-15 2000-03-14 Target Therapeutics, Inc. Sheet metal aneurysm neck bridge
US6045570A (en) * 1997-02-11 2000-04-04 Biointerventional Corporation Biological sealant mixture and system for use in percutaneous occlusion of puncture sites and tracts in the human body and method
US6056769A (en) * 1997-02-11 2000-05-02 Biointerventional Corporation Expansile device for use in blood vessels and tracts in the body and tension application device for use therewith and method
US6063085A (en) * 1992-04-23 2000-05-16 Scimed Life Systems, Inc. Apparatus and method for sealing vascular punctures
US6080183A (en) * 1998-11-24 2000-06-27 Embol-X, Inc. Sutureless vessel plug and methods of use
US6110184A (en) * 1999-08-04 2000-08-29 Weadock; Kevin S. Introducer with vascular sealing mechanism
US6197042B1 (en) * 2000-01-05 2001-03-06 Medical Technology Group, Inc. Vascular sheath with puncture site closure apparatus and methods of use
US6334865B1 (en) * 1998-08-04 2002-01-01 Fusion Medical Technologies, Inc. Percutaneous tissue track closure assembly and method
US6348064B1 (en) * 2000-09-01 2002-02-19 Angiolink Corporation Wound site management and wound closure device
US20020026215A1 (en) * 1998-08-04 2002-02-28 Redmond Russell J. Percutaneous tissue track closure assembly and method
US6391048B1 (en) * 2000-01-05 2002-05-21 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US20020072768A1 (en) * 2000-12-07 2002-06-13 Ginn Richard S. Apparatus and methods for providing tactile feedback while delivering a closure device
US20020077657A1 (en) * 2000-12-14 2002-06-20 Integrated Vascular Systems, Inc. Apparatus and methods for sealing vascular punctures
US6409739B1 (en) * 1997-05-19 2002-06-25 Cardio Medical Solutions, Inc. Device and method for assisting end-to side anastomosis
US20030009180A1 (en) * 1999-09-13 2003-01-09 Hinchliffe Peter W.J. Vascular hole closure device
US6547806B1 (en) * 2000-02-04 2003-04-15 Ni Ding Vascular sealing device and method of use
US20030078598A1 (en) * 2000-01-05 2003-04-24 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US20030093096A1 (en) * 1999-09-13 2003-05-15 Mcguckin James F. Vascular closure
US6582452B2 (en) * 2000-09-08 2003-06-24 James Coleman Surgical stapler
US20040009289A1 (en) * 2000-12-07 2004-01-15 Carley Michael T. Closure device and methods for making and using them
US6695867B2 (en) * 2002-02-21 2004-02-24 Integrated Vascular Systems, Inc. Plunger apparatus and methods for delivering a closure device
US6719777B2 (en) * 2000-12-07 2004-04-13 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US20060020270A1 (en) * 2003-01-30 2006-01-26 Ronald Jabba Clip applier and methods of use
US7008435B2 (en) * 2001-08-09 2006-03-07 Christy Cummins Surgical stapling device and method
US20060135989A1 (en) * 2000-12-07 2006-06-22 Carley Michael T Closure device
US20060144479A1 (en) * 2002-12-31 2006-07-06 Integrated Vascular Systems, Inc. Methods for manufacturing a clip and clip
US20070010854A1 (en) * 2001-06-07 2007-01-11 Christy Cummins Surgical Staple
US7163551B2 (en) * 2001-08-09 2007-01-16 Thomas Anthony Surgical stapling device

Family Cites Families (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1088393A (en) * 1913-09-20 1914-02-24 Oscar E Backus Button.
US1331401A (en) * 1919-09-12 1920-02-17 Summers Henry Clay Button-fastening
US2316297A (en) * 1943-01-15 1943-04-13 Beverly A Southerland Surgical instrument
US2969887A (en) * 1959-04-08 1961-01-31 American Thermos Products Comp Threaded pouring lip stopper combination for vacuum bottle
US3015403A (en) * 1959-04-08 1962-01-02 American Thermos Products Comp Threaded stopper expanding pouring lip combination for vacuum bottle
US3604425A (en) 1969-04-11 1971-09-14 New Research And Dev Lab Inc Hemostatic clip
US3757629A (en) 1971-05-10 1973-09-11 R Schneider Resilient plastic staple
NL7403762A (en) * 1974-03-20 1975-09-23 Leer Koninklijke Emballage Plug of plastics or the like material, provided with external screw thread.
US4014492A (en) * 1975-06-11 1977-03-29 Senco Products, Inc. Surgical staple
US4207870A (en) * 1978-06-15 1980-06-17 Becton, Dickinson And Company Blood sampling assembly having porous vent means vein entry indicator
US4318401A (en) * 1980-04-24 1982-03-09 President And Fellows Of Harvard College Percutaneous vascular access portal and catheter
US4428376A (en) * 1980-05-02 1984-01-31 Ethicon Inc. Plastic surgical staple
US4485816A (en) 1981-06-25 1984-12-04 Alchemia Shape-memory surgical staple apparatus and method for use in surgical suturing
US4724840A (en) * 1982-02-03 1988-02-16 Ethicon, Inc. Surgical fastener applier with rotatable front housing and laterally extending curved needle for guiding a flexible pusher
DE3204522C2 (en) * 1982-02-10 1988-08-25 B. Braun Melsungen Ag, 3508 Melsungen, De
DE3204532C2 (en) * 1982-02-10 1983-12-08 B. Braun Melsungen Ag, 3508 Melsungen, De
US4934364A (en) * 1982-09-30 1990-06-19 United States Surgical Corporation Surgical clip applying apparatus having fixed jams
US4510251A (en) * 1982-11-08 1985-04-09 Abbott Laboratories Fluorescent polarization assay for ligands using aminomethylfluorescein derivatives as tracers
US4525157A (en) * 1983-07-28 1985-06-25 Manresa, Inc. Closed system catheter with guide wire
US4665906A (en) * 1983-10-14 1987-05-19 Raychem Corporation Medical devices incorporating sim alloy elements
US4510252A (en) * 1983-11-18 1985-04-09 Owens-Corning Fiberglas Corporation Easily formed chemically resistant glass fibers
US4635634A (en) * 1985-07-12 1987-01-13 Santos Manuel V Surgical clip applicator system
JPH0522551B2 (en) * 1986-04-09 1993-03-29 Terumo Corp
US4777950A (en) 1986-04-11 1988-10-18 Kees Surgical Specialty Co. Vascular clip
US4738658A (en) * 1986-09-19 1988-04-19 Aries Medical Incorporated Tapered hemostatic device for use in conjunction with a catheter for alleviating blood leakage and method for using same
USRE34866E (en) * 1987-02-17 1995-02-21 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
US4744364A (en) * 1987-02-17 1988-05-17 Intravascular Surgical Instruments, Inc. Device for sealing percutaneous puncture in a vessel
US4865026A (en) 1987-04-23 1989-09-12 Barrett David M Sealing wound closure device
US4836204A (en) * 1987-07-06 1989-06-06 Landymore Roderick W Method for effecting closure of a perforation in the septum of the heart
US5015247A (en) * 1988-06-13 1991-05-14 Michelson Gary K Threaded spinal implant
FR2641692B1 (en) * 1989-01-17 1995-05-12 Nippon Zeon Co
GB8924806D0 (en) * 1989-11-03 1989-12-20 Neoligaments Ltd Prosthectic ligament system
US5061274A (en) 1989-12-04 1991-10-29 Kensey Nash Corporation Plug device for sealing openings and method of use
US5156609A (en) 1989-12-26 1992-10-20 Nakao Naomi L Endoscopic stapling device and method
US5021059A (en) * 1990-05-07 1991-06-04 Kensey Nash Corporation Plug device with pulley for sealing punctures in tissue and methods of use
US5192300A (en) * 1990-10-01 1993-03-09 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
CA2027427A1 (en) * 1990-10-12 1992-04-13 William S. Laidlaw Plug for sealing wood preservative in wood structures
US5053008A (en) 1990-11-21 1991-10-01 Sandeep Bajaj Intracardiac catheter
US5366458A (en) 1990-12-13 1994-11-22 United States Surgical Corporation Latchless surgical clip
US5290310A (en) * 1991-10-30 1994-03-01 Howmedica, Inc. Hemostatic implant introducer
US5411520A (en) * 1991-11-08 1995-05-02 Kensey Nash Corporation Hemostatic vessel puncture closure system utilizing a plug located within the puncture tract spaced from the vessel, and method of use
US6056768A (en) * 1992-01-07 2000-05-02 Cates; Christopher U. Blood vessel sealing system
WO1993020768A1 (en) * 1992-04-13 1993-10-28 Ep Technologies, Inc. Steerable microwave antenna systems for cardiac ablation
JPH0647050A (en) * 1992-06-04 1994-02-22 Olympus Optical Co Ltd Tissue suture and ligature device
US5413571A (en) * 1992-07-16 1995-05-09 Sherwood Medical Company Device for sealing hemostatic incisions
US5290243A (en) * 1992-07-16 1994-03-01 Technalytics, Inc. Trocar system
US5292332A (en) * 1992-07-27 1994-03-08 Lee Benjamin I Methods and device for percutanceous sealing of arterial puncture sites
US5306254A (en) * 1992-10-01 1994-04-26 Kensey Nash Corporation Vessel position locating device and method of use
CZ281454B6 (en) * 1992-11-23 1996-10-16 Milan Mudr. Csc. Krajíček Aid for non-surgical closing of a hole in a vessel wall
US5417699A (en) * 1992-12-10 1995-05-23 Perclose Incorporated Device and method for the percutaneous suturing of a vascular puncture site
US5292309A (en) * 1993-01-22 1994-03-08 Schneider (Usa) Inc. Surgical depth measuring instrument and method
US5320639A (en) * 1993-03-12 1994-06-14 Meadox Medicals, Inc. Vascular plug delivery system
US5478354A (en) 1993-07-14 1995-12-26 United States Surgical Corporation Wound closing apparatus and method
US5830125A (en) 1993-08-12 1998-11-03 Scribner-Browne Medical Design Incorporated Catheter introducer with suture capability
US5725554A (en) * 1993-10-08 1998-03-10 Richard-Allan Medical Industries, Inc. Surgical staple and stapler
US5728122A (en) * 1994-01-18 1998-03-17 Datascope Investment Corp. Guide wire with releaseable barb anchor
US5416584A (en) * 1994-04-25 1995-05-16 Honeywell Inc. Sinusoidal noise injection into the dither of a ring laser gyroscope
US5478309A (en) * 1994-05-27 1995-12-26 William P. Sweezer, Jr. Catheter system and method for providing cardiopulmonary bypass pump support during heart surgery
US5732872A (en) * 1994-06-17 1998-03-31 Heartport, Inc. Surgical stapling instrument
US5620452A (en) * 1994-12-22 1997-04-15 Yoon; Inbae Surgical clip with ductile tissue penetrating members
US5695505A (en) 1995-03-09 1997-12-09 Yoon; Inbae Multifunctional spring clips and cartridges and applicators therefor
US5634911A (en) * 1995-05-19 1997-06-03 General Surgical Innovations, Inc. Screw-type skin seal with inflatable membrane
US5810846A (en) 1995-08-03 1998-09-22 United States Surgical Corporation Vascular hole closure
US5683405A (en) 1995-08-25 1997-11-04 Research Medical Inc. Vascular occluder
US5674231A (en) 1995-10-20 1997-10-07 United States Surgical Corporation Apparatus and method for vascular hole closure
EP0874591B1 (en) 1995-12-07 2011-04-06 Loma Linda University Medical Center Vascular wound closure device
US6425901B1 (en) 1995-12-07 2002-07-30 Loma Linda University Medical Center Vascular wound closure system
US5810851A (en) 1996-03-05 1998-09-22 Yoon; Inbae Suture spring device
US5728132A (en) * 1996-04-08 1998-03-17 Tricardia, L.L.C. Self-sealing vascular access device
US5855312A (en) * 1996-07-25 1999-01-05 Toledano; Haviv Flexible annular stapler for closed surgery of hollow organs
US5902310A (en) * 1996-08-12 1999-05-11 Ethicon Endo-Surgery, Inc. Apparatus and method for marking tissue
GB2318295A (en) * 1996-10-17 1998-04-22 Malachy Gleeson Wire-guided surgical stapler for closure of a puncture site in a blood vessel
US5861005A (en) * 1997-02-11 1999-01-19 X-Site, L.L.C. Arterial stapling device
US6056770A (en) * 1997-02-11 2000-05-02 Biointerventional Corporation Expansile device for use in blood vessels and tracts in the body and method
US5984934A (en) 1997-10-10 1999-11-16 Applied Medical Resources Corporation Low-profile surgical clip
US6726704B1 (en) * 1998-05-29 2004-04-27 By-Pass, Inc. Advanced closure device
WO2000056227A1 (en) 1999-03-19 2000-09-28 By-Pass, Inc. Advanced closure device
CN1352539A (en) 1999-03-19 2002-06-05 拜帕斯公司 Vascular surgery
US7396359B1 (en) 1998-05-29 2008-07-08 Bypass, Inc. Vascular port device
US6048358A (en) * 1998-07-13 2000-04-11 Barak; Shlomo Method and apparatus for hemostasis following arterial catheterization
WO2000007640A2 (en) 1998-07-22 2000-02-17 Angiolink Corporation Vascular suction cannula, dilator and surgical stapler
US6780197B2 (en) * 2000-01-05 2004-08-24 Integrated Vascular Systems, Inc. Apparatus and methods for delivering a vascular closure device to a body lumen
US6533762B2 (en) * 2000-09-01 2003-03-18 Angiolink Corporation Advanced wound site management systems and methods
US6767356B2 (en) * 2000-09-01 2004-07-27 Angiolink Corporation Advanced wound site management systems and methods
US7513537B2 (en) * 2003-10-22 2009-04-07 Frank's Casing Crew & Rental Tools, Inc. Tubular connection with slotted threads
US7326230B2 (en) * 2003-10-23 2008-02-05 Sundaram Ravikumar Vascular sealing device and method of use

Patent Citations (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2583625A (en) * 1946-10-29 1952-01-29 Thomas & Betts Corp Method of and tool for crimping tubes
US3120230A (en) * 1960-10-24 1964-02-04 Jack H Sanders Surgical clamp
US3523351A (en) * 1967-10-20 1970-08-11 Sargent & Co Locator and holder in a crimping tool for an electrical connector
US3586002A (en) * 1968-01-08 1971-06-22 Ernest C Wood Surgical skin clip
US3677243A (en) * 1971-09-24 1972-07-18 Extracorporeal Med Spec Separable surgical needle
US3828791A (en) * 1973-03-21 1974-08-13 M Santos Surgical instruments
US3805337A (en) * 1973-04-23 1974-04-23 Raymond Lee Organization Inc Spring wire hose clamp
US4192315A (en) * 1976-12-23 1980-03-11 Aesculap-Werke Aktiengesellschaft Vormals Jetter & Scheerer Clip for surgical purposes
US4217902A (en) * 1977-05-02 1980-08-19 March Alfred L Hemostatic clip
US4201215A (en) * 1977-09-06 1980-05-06 Crossett E S Apparatus and method for closing a severed sternum
US4345606A (en) * 1977-12-13 1982-08-24 Littleford Philip O Split sleeve introducers for pacemaker electrodes and the like
USRE31855F1 (en) * 1978-12-01 1986-08-19 Tear apart cannula
USRE31855E (en) * 1978-12-01 1985-03-26 Cook, Inc. Tear apart cannula
US4440170A (en) * 1979-03-06 1984-04-03 Ethicon, Inc. Surgical clip applying instrument
US4396139A (en) * 1980-02-15 1983-08-02 Technalytics, Inc. Surgical stapling system, apparatus and staple
US4327485A (en) * 1980-05-21 1982-05-04 Amp Incorporated Pistol grip tool
US4505274A (en) * 1980-10-17 1985-03-19 Propper Manufacturing Co., Inc. Suture clip
US4860746A (en) * 1982-04-20 1989-08-29 Inbae Yoon Elastic surgical ring clip and ring loader
US4586503A (en) * 1983-12-01 1986-05-06 University Of New Mexico Surgical microclip
US4917087A (en) * 1984-04-10 1990-04-17 Walsh Manufacturing (Mississuaga) Limited Anastomosis devices, kits and method
US4687469A (en) * 1984-06-01 1987-08-18 Peter Osypka Device for slitting introducers for pacemaker electrodes
US4635635A (en) * 1984-11-29 1987-01-13 Aspen Laboratories, Inc. Tourniquet cuff
US4759364A (en) * 1985-09-19 1988-07-26 Richard Wolf Gmbh Pincers attachment for a surgical handle to be used in endoscopy
US5100418A (en) * 1987-05-14 1992-03-31 Inbae Yoon Suture tie device system and applicator therefor
US4950258A (en) * 1988-01-28 1990-08-21 Japan Medical Supply Co., Ltd. Plastic molded articles with shape memory property
US5007921A (en) * 1989-10-26 1991-04-16 Brown Alan W Surgical staple
US5026390A (en) * 1989-10-26 1991-06-25 Brown Alan W Surgical staple
US5192302A (en) * 1989-12-04 1993-03-09 Kensey Nash Corporation Plug devices for sealing punctures and methods of use
US5032127A (en) * 1990-03-07 1991-07-16 Frazee John G Hemostatic clip and applicator therefor
US5116349A (en) * 1990-05-23 1992-05-26 United States Surgical Corporation Surgical fastener apparatus
US5078731A (en) * 1990-06-05 1992-01-07 Hayhurst John O Suture clip
US5275616A (en) * 1990-10-01 1994-01-04 Quinton Instrument Company Insertion assembly and method of inserting a vessel plug into the body of a patient
US5275616B1 (en) * 1990-10-01 1996-01-23 Quinton Instr Insertion assembly and method of inserting a vessel plug into the body of a patient
US5425489A (en) * 1990-12-20 1995-06-20 United States Surgical Corporation Fascia clip and instrument
US5108420A (en) * 1991-02-01 1992-04-28 Temple University Aperture occlusion device
US5392978A (en) * 1991-02-08 1995-02-28 United States Surgical Corporation Surgical staple and endoscopic stapler
US5935147A (en) * 1991-11-08 1999-08-10 Kensey Nash Corporation Hemostatic puncture closure system and method of use
US5222974A (en) * 1991-11-08 1993-06-29 Kensey Nash Corporation Hemostatic puncture closure system and method of use
US5176648A (en) * 1991-12-13 1993-01-05 Unisurge, Inc. Introducer assembly and instrument for use therewith
US5318542A (en) * 1992-01-08 1994-06-07 Suddeutsche Feinmechanik Gmbh Split cannula and process for the production thereof
US5334217A (en) * 1992-01-21 1994-08-02 Regents Of The University Of Minnesota Septal defect closure device
US6077281A (en) * 1992-01-21 2000-06-20 Regents Of The University Of Minnesota Septal defect closure device
US6077291A (en) * 1992-01-21 2000-06-20 Regents Of The University Of Minnesota Septal defect closure device
US5340360A (en) * 1992-03-06 1994-08-23 Ethicon, Inc. Ligating clip applier
US6063085A (en) * 1992-04-23 2000-05-16 Scimed Life Systems, Inc. Apparatus and method for sealing vascular punctures
US5413584A (en) * 1992-05-11 1995-05-09 Ethicon, Inc. "Omega"-shaped staple for surgical, especially endoscopic, purposes
US5547474A (en) * 1992-05-26 1996-08-20 Origin Medsystems, Incorporated Surgical clip closure apparatus with safety stop
US5431667A (en) * 1992-05-26 1995-07-11 Origin Medsystems, Inc. Gas-sealed instruments for use in laparoscopic surgery
US5282808A (en) * 1992-05-26 1994-02-01 Origin Medsystems, Inc. Closure prevention apparatus for surgical clip applier
US5192288A (en) * 1992-05-26 1993-03-09 Origin Medsystems, Inc. Surgical clip applier
US5618291A (en) * 1992-05-26 1997-04-08 Origin Medsystems, Inc. Gas-sealed instruments for use in laparoscopic surgery
US5304184A (en) * 1992-10-19 1994-04-19 Indiana University Foundation Apparatus and method for positive closure of an internal tissue membrane opening
US5507755A (en) * 1993-08-03 1996-04-16 Origin Medsystems, Inc. Apparatus and method for closing puncture wounds
US5423857A (en) * 1993-11-02 1995-06-13 Ethicon, Inc. Three piece surgical staple
US5527322A (en) * 1993-11-08 1996-06-18 Perclose, Inc. Device and method for suturing of internal puncture sites
US5728114A (en) * 1994-08-24 1998-03-17 Kensey Nash Corporation Apparatus and methods of use for preventing blood seepage at a percutaneous puncture site
US5904697A (en) * 1995-02-24 1999-05-18 Heartport, Inc. Devices and methods for performing a vascular anastomosis
US5782844A (en) * 1996-03-05 1998-07-21 Inbae Yoon Suture spring device applicator
US5879366A (en) * 1996-12-20 1999-03-09 W.L. Gore & Associates, Inc. Self-expanding defect closure device and method of making and using
US6080182A (en) * 1996-12-20 2000-06-27 Gore Enterprise Holdings, Inc. Self-expanding defect closure device and method of making and using
US5782861A (en) * 1996-12-23 1998-07-21 Sub Q Inc. Percutaneous hemostasis device
US5782860A (en) * 1997-02-11 1998-07-21 Biointerventional Corporation Closure device for percutaneous occlusion of puncture sites and tracts in the human body and method
US6056769A (en) * 1997-02-11 2000-05-02 Biointerventional Corporation Expansile device for use in blood vessels and tracts in the body and tension application device for use therewith and method
US6045570A (en) * 1997-02-11 2000-04-04 Biointerventional Corporation Biological sealant mixture and system for use in percutaneous occlusion of puncture sites and tracts in the human body and method
US5922009A (en) * 1997-02-11 1999-07-13 Biointerventional Coporation Expansile device for use in blood vessels and tracts in the body and tension application device for use therewith and method
US6409739B1 (en) * 1997-05-19 2002-06-25 Cardio Medical Solutions, Inc. Device and method for assisting end-to side anastomosis
US6030364A (en) * 1997-10-03 2000-02-29 Boston Scientific Corporation Apparatus and method for percutaneous placement of gastro-intestinal tubes
US6036720A (en) * 1997-12-15 2000-03-14 Target Therapeutics, Inc. Sheet metal aneurysm neck bridge
US5910155A (en) * 1998-06-05 1999-06-08 United States Surgical Corporation Vascular wound closure system
US20020026215A1 (en) * 1998-08-04 2002-02-28 Redmond Russell J. Percutaneous tissue track closure assembly and method
US6334865B1 (en) * 1998-08-04 2002-01-01 Fusion Medical Technologies, Inc. Percutaneous tissue track closure assembly and method
US6080183A (en) * 1998-11-24 2000-06-27 Embol-X, Inc. Sutureless vessel plug and methods of use
US6110184A (en) * 1999-08-04 2000-08-29 Weadock; Kevin S. Introducer with vascular sealing mechanism
US20030009180A1 (en) * 1999-09-13 2003-01-09 Hinchliffe Peter W.J. Vascular hole closure device
US20030093096A1 (en) * 1999-09-13 2003-05-15 Mcguckin James F. Vascular closure
US20030078598A1 (en) * 2000-01-05 2003-04-24 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US6391048B1 (en) * 2000-01-05 2002-05-21 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US6277140B2 (en) * 2000-01-05 2001-08-21 Integrated Vascular Systems, Inc. Vascular sheath with puncture site closure apparatus and methods of use
US6197042B1 (en) * 2000-01-05 2001-03-06 Medical Technology Group, Inc. Vascular sheath with puncture site closure apparatus and methods of use
US6547806B1 (en) * 2000-02-04 2003-04-15 Ni Ding Vascular sealing device and method of use
US20030125766A1 (en) * 2000-02-04 2003-07-03 Ni Ding Vascular sealing device and method of use
US6348064B1 (en) * 2000-09-01 2002-02-19 Angiolink Corporation Wound site management and wound closure device
US6582452B2 (en) * 2000-09-08 2003-06-24 James Coleman Surgical stapler
US7001398B2 (en) * 2000-12-07 2006-02-21 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US20020072768A1 (en) * 2000-12-07 2002-06-13 Ginn Richard S. Apparatus and methods for providing tactile feedback while delivering a closure device
US20040009289A1 (en) * 2000-12-07 2004-01-15 Carley Michael T. Closure device and methods for making and using them
US20060167484A1 (en) * 2000-12-07 2006-07-27 Carley Michael T Closure device and methods for making and using them
US6719777B2 (en) * 2000-12-07 2004-04-13 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US20060135989A1 (en) * 2000-12-07 2006-06-22 Carley Michael T Closure device
US7211101B2 (en) * 2000-12-07 2007-05-01 Abbott Vascular Devices Methods for manufacturing a clip and clip
US20040073236A1 (en) * 2000-12-07 2004-04-15 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US20050119695A1 (en) * 2000-12-07 2005-06-02 Carley Michael T. Closure device and methods for making and using them
US20020077657A1 (en) * 2000-12-14 2002-06-20 Integrated Vascular Systems, Inc. Apparatus and methods for sealing vascular punctures
US20070010854A1 (en) * 2001-06-07 2007-01-11 Christy Cummins Surgical Staple
US7163551B2 (en) * 2001-08-09 2007-01-16 Thomas Anthony Surgical stapling device
US7008435B2 (en) * 2001-08-09 2006-03-07 Christy Cummins Surgical stapling device and method
US20040073255A1 (en) * 2002-02-21 2004-04-15 Ginn Richard S Plunger apparatus and methods for delivering a closure device
US6695867B2 (en) * 2002-02-21 2004-02-24 Integrated Vascular Systems, Inc. Plunger apparatus and methods for delivering a closure device
US6749621B2 (en) * 2002-02-21 2004-06-15 Integrated Vascular Systems, Inc. Sheath apparatus and methods for delivering a closure device
US20060144479A1 (en) * 2002-12-31 2006-07-06 Integrated Vascular Systems, Inc. Methods for manufacturing a clip and clip
US20060020270A1 (en) * 2003-01-30 2006-01-26 Ronald Jabba Clip applier and methods of use

Cited By (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8758396B2 (en) 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US9050087B2 (en) 2000-01-05 2015-06-09 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US8758400B2 (en) 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Closure system and methods of use
US10111664B2 (en) 2000-01-05 2018-10-30 Integrated Vascular Systems, Inc. Closure system and methods of use
US7931669B2 (en) 2000-01-05 2011-04-26 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US7819895B2 (en) 2000-01-05 2010-10-26 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US7828817B2 (en) 2000-01-05 2010-11-09 Integrated Vascular Systems, Inc. Apparatus and methods for delivering a closure device
US7901428B2 (en) 2000-01-05 2011-03-08 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US8956388B2 (en) 2000-01-05 2015-02-17 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant
US9579091B2 (en) 2000-01-05 2017-02-28 Integrated Vascular Systems, Inc. Closure system and methods of use
US9402625B2 (en) 2000-09-08 2016-08-02 Abbott Vascular Inc. Surgical stapler
US8784447B2 (en) 2000-09-08 2014-07-22 Abbott Vascular Inc. Surgical stapler
US9089674B2 (en) 2000-10-06 2015-07-28 Integrated Vascular Systems, Inc. Apparatus and methods for positioning a vascular sheath
US8236026B2 (en) 2000-12-07 2012-08-07 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8690910B2 (en) 2000-12-07 2014-04-08 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7879071B2 (en) 2000-12-07 2011-02-01 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7842068B2 (en) 2000-12-07 2010-11-30 Integrated Vascular Systems, Inc. Apparatus and methods for providing tactile feedback while delivering a closure device
US7806904B2 (en) 2000-12-07 2010-10-05 Integrated Vascular Systems, Inc. Closure device
US8257390B2 (en) 2000-12-07 2012-09-04 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8128644B2 (en) 2000-12-07 2012-03-06 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US10245013B2 (en) 2000-12-07 2019-04-02 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8182497B2 (en) 2000-12-07 2012-05-22 Integrated Vascular Systems, Inc. Closure device
US9554786B2 (en) 2000-12-07 2017-01-31 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US9320522B2 (en) 2000-12-07 2016-04-26 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8603136B2 (en) 2000-12-07 2013-12-10 Integrated Vascular Systems, Inc. Apparatus and methods for providing tactile feedback while delivering a closure device
US9585646B2 (en) 2000-12-07 2017-03-07 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8486092B2 (en) 2000-12-07 2013-07-16 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8597325B2 (en) 2000-12-07 2013-12-03 Integrated Vascular Systems, Inc. Apparatus and methods for providing tactile feedback while delivering a closure device
US9345460B2 (en) 2001-04-24 2016-05-24 Cardiovascular Technologies, Inc. Tissue closure devices, device and systems for delivery, kits and methods therefor
US8992567B1 (en) 2001-04-24 2015-03-31 Cardiovascular Technologies Inc. Compressible, deformable, or deflectable tissue closure devices and method of manufacture
US8518063B2 (en) 2001-04-24 2013-08-27 Russell A. Houser Arteriotomy closure devices and techniques
US7918873B2 (en) 2001-06-07 2011-04-05 Abbott Vascular Inc. Surgical staple
US8728119B2 (en) 2001-06-07 2014-05-20 Abbott Vascular Inc. Surgical staple
US7887563B2 (en) 2001-06-07 2011-02-15 Abbott Vascular Inc. Surgical staple
US8579932B2 (en) 2002-02-21 2013-11-12 Integrated Vascular Systems, Inc. Sheath apparatus and methods for delivering a closure device
US10201340B2 (en) 2002-02-21 2019-02-12 Integrated Vascular Systems, Inc. Sheath apparatus and methods for delivering a closure device
US9498196B2 (en) 2002-02-21 2016-11-22 Integrated Vascular Systems, Inc. Sheath apparatus and methods for delivering a closure device
US8007512B2 (en) 2002-02-21 2011-08-30 Integrated Vascular Systems, Inc. Plunger apparatus and methods for delivering a closure device
US9295469B2 (en) 2002-06-04 2016-03-29 Abbott Vascular Inc. Blood vessel closure clip and delivery device
US9980728B2 (en) 2002-06-04 2018-05-29 Abbott Vascular Inc Blood vessel closure clip and delivery device
US7850709B2 (en) 2002-06-04 2010-12-14 Abbott Vascular Inc. Blood vessel closure clip and delivery device
US8469995B2 (en) 2002-06-04 2013-06-25 Abbott Vascular Inc. Blood vessel closure clip and delivery device
US8192459B2 (en) 2002-06-04 2012-06-05 Abbott Vascular Inc. Blood vessel closure clip and delivery device
US20080132915A1 (en) * 2002-09-13 2008-06-05 Buckman Robert F Method and apparatus for vascular and visceral clipping
US7322995B2 (en) * 2002-09-13 2008-01-29 Damage Control Surgical Technologies, Inc. Method and apparatus for vascular and visceral clipping
US20050251183A1 (en) * 2002-09-13 2005-11-10 Damage Control Surgical Technologies, Inc. Method and apparatus for vascular and visceral clipping
US8187290B2 (en) 2002-09-13 2012-05-29 Damage Control Surgical Technologies, Inc. Method and apparatus for vascular and visceral clipping
US8202283B2 (en) 2002-12-31 2012-06-19 Integrated Vascular Systems, Inc. Methods for manufacturing a clip and clip
US8585836B2 (en) 2002-12-31 2013-11-19 Integrated Vascular Systems, Inc. Methods for manufacturing a clip and clip
US7854810B2 (en) 2002-12-31 2010-12-21 Integrated Vascular Systems, Inc. Methods for manufacturing a clip and clip
US9271707B2 (en) 2003-01-30 2016-03-01 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8398656B2 (en) 2003-01-30 2013-03-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8202293B2 (en) 2003-01-30 2012-06-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US7905900B2 (en) 2003-01-30 2011-03-15 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8926656B2 (en) 2003-01-30 2015-01-06 Integated Vascular Systems, Inc. Clip applier and methods of use
US7857828B2 (en) 2003-01-30 2010-12-28 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8529587B2 (en) 2003-01-30 2013-09-10 Integrated Vascular Systems, Inc. Methods of use of a clip applier
US9398914B2 (en) 2003-01-30 2016-07-26 Integrated Vascular Systems, Inc. Methods of use of a clip applier
US9241706B2 (en) 2003-09-15 2016-01-26 Abbott Laboratories Suture locking device and methods
US8590760B2 (en) 2004-05-25 2013-11-26 Abbott Vascular Inc. Surgical stapler
US8926633B2 (en) 2005-06-24 2015-01-06 Abbott Laboratories Apparatus and method for delivering a closure element
US9050068B2 (en) 2005-07-01 2015-06-09 Abbott Laboratories Clip applier and methods of use
US8518057B2 (en) 2005-07-01 2013-08-27 Abbott Laboratories Clip applier and methods of use
US10085753B2 (en) 2005-07-01 2018-10-02 Abbott Laboratories Clip applier and methods of use
US8920442B2 (en) 2005-08-24 2014-12-30 Abbott Vascular Inc. Vascular opening edge eversion methods and apparatuses
US8808310B2 (en) 2006-04-20 2014-08-19 Integrated Vascular Systems, Inc. Resettable clip applier and reset tools
US9962144B2 (en) 2006-06-28 2018-05-08 Abbott Laboratories Vessel closure device
USD611144S1 (en) 2006-06-28 2010-03-02 Abbott Laboratories Apparatus for delivering a closure element
US8556930B2 (en) 2006-06-28 2013-10-15 Abbott Laboratories Vessel closure device
US8758398B2 (en) 2006-09-08 2014-06-24 Integrated Vascular Systems, Inc. Apparatus and method for delivering a closure element
US8226681B2 (en) 2007-06-25 2012-07-24 Abbott Laboratories Methods, devices, and apparatus for managing access through tissue
US8961541B2 (en) 2007-12-03 2015-02-24 Cardio Vascular Technologies Inc. Vascular closure devices, systems, and methods of use
US8893947B2 (en) 2007-12-17 2014-11-25 Abbott Laboratories Clip applier and methods of use
US8672953B2 (en) 2007-12-17 2014-03-18 Abbott Laboratories Tissue closure system and methods of use
US7841502B2 (en) 2007-12-18 2010-11-30 Abbott Laboratories Modular clip applier
US8820602B2 (en) 2007-12-18 2014-09-02 Abbott Laboratories Modular clip applier
US9282965B2 (en) 2008-05-16 2016-03-15 Abbott Laboratories Apparatus and methods for engaging tissue
US8657852B2 (en) 2008-10-30 2014-02-25 Abbott Vascular Inc. Closure device
US9241696B2 (en) 2008-10-30 2016-01-26 Abbott Vascular Inc. Closure device
US8858594B2 (en) 2008-12-22 2014-10-14 Abbott Laboratories Curved closure device
US9314230B2 (en) 2009-01-09 2016-04-19 Abbott Vascular Inc. Closure device with rapidly eroding anchor
US9089311B2 (en) 2009-01-09 2015-07-28 Abbott Vascular Inc. Vessel closure devices and methods
US9486191B2 (en) 2009-01-09 2016-11-08 Abbott Vascular, Inc. Closure devices
US9414824B2 (en) 2009-01-16 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US9585647B2 (en) 2009-08-26 2017-03-07 Abbott Laboratories Medical device for repairing a fistula
US8758399B2 (en) 2010-08-02 2014-06-24 Abbott Cardiovascular Systems, Inc. Expandable bioabsorbable plug apparatus and method
US8603116B2 (en) 2010-08-04 2013-12-10 Abbott Cardiovascular Systems, Inc. Closure device with long tines
US20120109189A1 (en) * 2010-11-01 2012-05-03 Abbott Cardiovascular Systems, Inc. Methods and systems for establishing hemostasis relative to a puncture
US8603137B2 (en) * 2010-11-01 2013-12-10 Abbott Cardiovascular Systems, Inc. Methods and systems for establishing hemostasis relative to a puncture
US8821534B2 (en) 2010-12-06 2014-09-02 Integrated Vascular Systems, Inc. Clip applier having improved hemostasis and methods of use
US8685047B2 (en) 2011-02-07 2014-04-01 Abbott Vascular, Inc. Scaffold device for preventing tissue trauma
US8617184B2 (en) 2011-02-15 2013-12-31 Abbott Cardiovascular Systems, Inc. Vessel closure system
US9149265B2 (en) 2011-02-26 2015-10-06 Abbott Cardiovascular Systems, Inc. Hinged tissue support device
US9468431B2 (en) 2011-02-26 2016-10-18 Abbott Cardiovascular Systems, Inc. Hinged tissue support device
US9955960B2 (en) 2011-02-26 2018-05-01 Abbott Cardiovascular Systems, Inc. Hinged tissue support device
US9149276B2 (en) 2011-03-21 2015-10-06 Abbott Cardiovascular Systems, Inc. Clip and deployment apparatus for tissue closure
US20140052125A1 (en) * 2011-04-08 2014-02-20 Coviden Lp Flexible microwave catheters for natural or artificial lumens
US8556932B2 (en) 2011-05-19 2013-10-15 Abbott Cardiovascular Systems, Inc. Collapsible plug for tissue closure
US9055932B2 (en) 2011-08-26 2015-06-16 Abbott Cardiovascular Systems, Inc. Suture fastener combination device
US9332976B2 (en) 2011-11-30 2016-05-10 Abbott Cardiovascular Systems, Inc. Tissue closure device
US9138214B2 (en) 2012-03-02 2015-09-22 Abbott Cardiovascular Systems, Inc. Suture securing systems, devices and methods
US9364209B2 (en) 2012-12-21 2016-06-14 Abbott Cardiovascular Systems, Inc. Articulating suturing device
US10143460B2 (en) 2013-01-17 2018-12-04 Abbott Cardiovascular Systems, Inc. Access device for accessing tissue
USD847988S1 (en) 2015-11-13 2019-05-07 Access Closure, Inc. Handle grip
USD843573S1 (en) 2015-11-13 2019-03-19 Access Closure, Inc. Vascular closure apparatus

Also Published As

Publication number Publication date
US20010007077A1 (en) 2001-07-05
US6632238B2 (en) 2003-10-14
US6197042B1 (en) 2001-03-06
US20020002386A1 (en) 2002-01-03
US6277140B2 (en) 2001-08-21
US20060190014A1 (en) 2006-08-24

Similar Documents

Publication Publication Date Title
EP1229841B1 (en) System for wound closure
US7150750B2 (en) Method and device for endoscopic suturing
US5972005A (en) Wound closure assembly and method of use
US6071300A (en) Apparatus and method for percutaneous sealing of blood vessel punctures
US7449024B2 (en) Suturing device with split arm and method of suturing tissue
US6964668B2 (en) Articulating suturing device and method
JP4313574B2 (en) Device for delivering the device and the device for sealing an opening through tissue
EP1322230B1 (en) Apparatus for positioning a vascular sheath
CA2417962C (en) Method and apparatus for closing vascular puncture using hemostatic material
AU758665B2 (en) Vascular suction cannula, dilator and surgical stapler
US9375214B2 (en) Apparatus and methods for facilitating hemostasis within a vascular puncture
US6077279A (en) Device and method employing adhesive for sealing blood vessels and the like
US8348962B2 (en) Suturing device and method
US6451031B1 (en) Blood vessel suturing device with single guide-wire/needle receiving lumen
US7850701B2 (en) Articulating suturing device and method
ES2264130T3 (en) Vascular hole closure.
CA2473451C (en) Vascular hole closure device
EP1750590B1 (en) Locator and delivery device
JP4399035B2 (en) Suturing apparatus for sealing an opening in the wall of the organism tissue
EP1416856B8 (en) Surgical stapling device and method
JP5028556B2 (en) Multi - clipping device
US8449572B2 (en) Tissue closure and tissue closing device
US6036699A (en) Device and method for suturing tissue
US4890612A (en) Device for sealing percutaneous puncture in a vessel
US5507744A (en) Apparatus and method for sealing vascular punctures

Legal Events

Date Code Title Description
STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION