US20060172313A1 - Methods and compositions for improving fidelity in a nucleic acid synthesis reaction - Google Patents

Methods and compositions for improving fidelity in a nucleic acid synthesis reaction Download PDF

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Publication number
US20060172313A1
US20060172313A1 US11/046,448 US4644805A US2006172313A1 US 20060172313 A1 US20060172313 A1 US 20060172313A1 US 4644805 A US4644805 A US 4644805A US 2006172313 A1 US2006172313 A1 US 2006172313A1
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Prior art keywords
nucleotide
triphosphate
method
derivative
nucleic acid
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US11/046,448
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US7482120B2 (en
Inventor
Philip Buzby
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Fluidigm Corp
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Helicos BioSciences Corp
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Priority to US11/046,448 priority Critical patent/US7482120B2/en
Assigned to HELICOS BIOSCIENCES CORPORATION reassignment HELICOS BIOSCIENCES CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: BUZBY, PHILIP RICHARD
Publication of US20060172313A1 publication Critical patent/US20060172313A1/en
Publication of US7482120B2 publication Critical patent/US7482120B2/en
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Assigned to GENERAL ELECTRIC CAPITAL CORPORATION reassignment GENERAL ELECTRIC CAPITAL CORPORATION SECURITY AGREEMENT Assignors: HELICOS BIOSCIENCES CORPORATION
Assigned to HELICOS BIOSCIENCES CORPORATION reassignment HELICOS BIOSCIENCES CORPORATION RELEASE BY SECURED PARTY (SEE DOCUMENT FOR DETAILS). Assignors: GENERAL ELECTRIC CAPITAL CORPORATION
Assigned to SEQLL, LLC reassignment SEQLL, LLC LICENSE (SEE DOCUMENT FOR DETAILS). Assignors: FLUIDIGM CORPORATION
Assigned to ILLUMINA, INC. reassignment ILLUMINA, INC. LICENSE (SEE DOCUMENT FOR DETAILS). Assignors: FLUIDIGM CORPORATION
Assigned to COMPLETE GENOMICS, INC. reassignment COMPLETE GENOMICS, INC. LICENSE (SEE DOCUMENT FOR DETAILS). Assignors: FLUIDIGM CORPORATION
Assigned to PACIFIC BIOSCIENCES OF CALIFORNIA, INC. reassignment PACIFIC BIOSCIENCES OF CALIFORNIA, INC. LICENSE (SEE DOCUMENT FOR DETAILS). Assignors: FLUIDIGM CORPORATION
Assigned to FLUIDIGM CORPORATION reassignment FLUIDIGM CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HELICOS BIOSCIENCES CORPORATION
Application status is Active legal-status Critical
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