US20060094983A1 - Methods and apparatus for securing medical instruments to desired locations in a patient's body - Google Patents

Methods and apparatus for securing medical instruments to desired locations in a patient's body Download PDF

Info

Publication number
US20060094983A1
US20060094983A1 US11303154 US30315405A US2006094983A1 US 20060094983 A1 US20060094983 A1 US 20060094983A1 US 11303154 US11303154 US 11303154 US 30315405 A US30315405 A US 30315405A US 2006094983 A1 US2006094983 A1 US 2006094983A1
Authority
US
Grant status
Application
Patent type
Prior art keywords
tissue
distal
end
instrument
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US11303154
Inventor
Fred Burbank
Paul Lubock
Michael Jones
Richard Quick
Original Assignee
Burbank Fred H
Paul Lubock
Jones Michael L
Quick Richard L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/04Endoscopic instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0241Pointed or sharp biopsy instruments for prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0266Pointed or sharp biopsy instruments means for severing sample
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491Surgical glue applicators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/32056Surgical snare instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1477Needle-like probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B90/14Fixators for body parts, e.g. skull clamps; Constructional details of fixators, e.g. pins
    • A61B90/17Fixators for body parts, e.g. skull clamps; Constructional details of fixators, e.g. pins for soft tissue, e.g. breast-holding devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3205Excision instruments
    • A61B17/3207Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320725Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with radially expandable cutting or abrading elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3417Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1487Trocar-like, i.e. devices producing an enlarged transcutaneous opening
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B2017/320064Surgical cutting instruments with tissue or sample retaining means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34Trocars; Puncturing needles
    • A61B2017/348Means for supporting the trocar against the body or retaining the trocar inside the body
    • A61B2017/3482Means for supporting the trocar against the body or retaining the trocar inside the body inside
    • A61B2017/3484Anchoring means, e.g. spreading-out umbrella-like structure
    • A61B2017/3488Fixation to inner organ or inner body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00184Moving parts
    • A61B2018/00202Moving parts rotating
    • A61B2018/00208Moving parts rotating actively driven, e.g. by a motor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00214Expandable means emitting energy, e.g. by elements carried thereon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00214Expandable means emitting energy, e.g. by elements carried thereon
    • A61B2018/00267Expandable means emitting energy, e.g. by elements carried thereon having a basket shaped structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00333Breast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00601Cutting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00898Alarms or notifications created in response to an abnormal condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/0091Handpieces of the surgical instrument or device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/0091Handpieces of the surgical instrument or device
    • A61B2018/00916Handpieces of the surgical instrument or device with means for switching or controlling the main function of the instrument or device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/1246Generators therefor characterised by the output polarity
    • A61B2018/1253Generators therefor characterised by the output polarity monopolar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/1246Generators therefor characterised by the output polarity
    • A61B2018/126Generators therefor characterised by the output polarity bipolar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1407Loop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1425Needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1475Electrodes retractable in or deployable from a housing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/16Indifferent or passive electrodes for grounding
    • A61B2018/162Indifferent or passive electrodes for grounding located on the probe body
    • A61B2019/5487
    • A61B2019/5491
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3904Markers, e.g. radio-opaque or breast lesions markers specially adapted for marking specified tissue
    • A61B2090/3908Soft tissue, e.g. breast tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3991Markers, e.g. radio-opaque or breast lesions markers having specific anchoring means to fixate the marker to the tissue, e.g. hooks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37Surgical systems with images on a monitor during operation

Abstract

Devices and methods are provided for securely affixing a medical instrument to desired tissue in a patient's body, using a fixation agent. Such medical instruments may comprise localization wires or tissue acquisition instruments, such as biopsy instruments, for example. In the case of tissue acquisition instruments, the inventors have discovered significant advantages for securely affixing the distal end of the tissue acquisition instrument to a particular tissue target area. For example, such an approach permits the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used. In a preferred embodiment, a bonding agent, such as adhesive, surgical glue, or a solvent, is used as the fixation agent.

Description

    FIELD OF THE INVENTION
  • [0001]
    The present invention relates to methods and devices for ensuring that a medical instrument remains in a desired location within a patient's body during a medical procedure, and more particularly to methods and devices for affixing a distal end of the medical instrument to the desired location using adhesives.
  • BACKGROUND OF THE INVENTION
  • [0002]
    It is often desirable and frequently necessary to sample or remove a portion of tissue from humans and other animals, particularly in the diagnosis and treatment of patients with cancerous tumors, pre-malignant conditions, and other diseases or disorders.
  • [0003]
    Typically, in the case of cancer, particularly cancer of the breast, there is a great emphasis on early detection and diagnosis through the use of screening modalities, such as physical examination, and particularly mammography, which is capable of detecting very small-abnormalities, often nonpalpable. When the physician establishes by means of a mammogram or other screening modality, such as ultrasound, that suspicious circumstances exist, a biopsy must be performed to capture tissue for a definitive diagnosis as to whether the suspicious lesion is cancerous. Biopsy may be done by an open or percutaneous technique. Open biopsy is a surgical procedure using a scalpel and involving direct vision of the target area, for removing the entire mass (excisional biopsy) or a part of the mass (incisional biopsy). Percutaneous biopsy, on the other hand, is usually done with a needle-like instrument through a relatively small incision, blindly or with the aid of an artificial imaging device, and may be either a fine needle aspiration (FNA) or a core biopsy. In FNA biopsy, individual cells or clusters of cells are obtained for cytologic examination and may be prepared such as in a Papanicolaou smear. In core biopsy, as the term suggests, a core or fragment of tissue is obtained for histologic examination which may be done via a frozen section or paraffin section.
  • [0004]
    The type of biopsy utilized depends in large part on circumstances present with respect to the patient, including the location of the lesion(s) within the body, and no single procedure is ideal for all cases. However, core biopsy is extremely useful in a number of conditions and is being used more frequently by the medical profession.
  • [0005]
    When an open surgical biopsy procedure is indicated, current practice dictates the use of lesion localization needles and devices, commonly referred to as “localization wires”, for use in localizing or marking non-palpable lesions and tumors within the body. These devices generally comprise a hypodermic needle or cannula which is inserted into the body under local anesthesia to the lesion or tissue of interest. The wire marker, or localization wire, is then passed through the cannula and extends through the lesion of interest so that the distal end thereof is anchored beyond the lesion. Thus, the lesion is marked for subsequent surgical procedures such as excision or biopsy. The anchoring procedure is typically accomplished by means of mechanical structure disposed at the distal end of the wire marker, such as a barb, hook, or the like, which is attached to surrounding tissue. After marking the lesion with the wire marker, the cannula is usually removed from the body, leaving the wire in place and extending from the body, for subsequent use by the surgeon during the biopsy procedure in identifying the lesion location. However, it often occurs that the barb or hook at the distal end of the wire marker attaches to something other than the tumor or lesion. For example, in the case of breast biopsies, the breast will typically be placed in compression during the imaging procedure in order to properly identify the location of the target lesion and place the localization wire. However, breast tissue is comprised of fibrous bands which, in compression, may be close to the target lesion and inadvertently engaged by the barb of the localization wire. Later, when the breast is released from compression prior to the surgical procedure, the fibrous bands will move away from the target lesion, and the distal end of the localization wire may thus move a substantial distance away from the target lesion.
  • [0006]
    It would be desirable, therefore, to develop a localization wire system and method wherein the distal end of the localization wire could be positively attached to the target lesion in order to minimize the possibility of migration of the distal end of the localization wire away from the target lesion between the imaging and surgical procedures.
  • [0007]
    In circumstances where a core biopsy procedure is indicated, various systems are available. Such systems are shown, for example, in U.S. Pat. No. 5,526,822 to Burbank et al, which discloses a probe having a laterally disposed tissue receiving port at the distal end thereof for acquiring relatively small tissue samples, and in U.S. Pat. No. 5,111,828 to Kornberg et al., which discloses a probe having an axially disposed tissue receiving port at the distal end thereof for acquiring relatively large intact tissue samples. Both of these patents are expressly incorporated by reference herein.
  • [0008]
    U.S. application Ser. No. 09/057,303 to Burbank et al., commonly assigned with the present application and expressly incorporated by reference herein, discloses still another core biopsy apparatus, which advantageously permits the acquisition of tissue samples which are larger in diameter than the diameter of the instrument lumen, thereby greatly increasing the chances of completely removing the target lesion and leaving “clean” margins thereabout.
  • [0009]
    As in the case of localization wires, there is some risk in using any of the foregoing devices that the distal end of the instrument will migrate away from the target lesion during the biopsy procedure, thereby reducing the likelihood of removing target tissue. Heretofore, in the case of core biopsy procedures, the risk of this occurrence is minimized by employing image guidance techniques during the entire tissue removal procedure. For example, in the case of the '822 Burbank et al. patent, a stereotactic imaging guidance system is typically utilized during the disclosed procedure. One disadvantage of this approach, however, is that the patient's breast must remain in compression during the entire procedure, with attendant discomfort and increased procedural difficulty, in order to properly utilize the imaging equipment. Furthermore, stereotactic imaging equipment or other suitable alternatives can cost as much as $400,000 or more and is not in the usual inventory of a typical community hospital. It would therefore be quite advantageous if a method and apparatus could be developed which would permit the uncoupling of the imaging environment from the procedural environment without undue risk that the active or cutting end of the core biopsy instrument would migrate away from the target lesion during the interval between the imaging procedure and the biopsy procedure.
  • SUMMARY OF THE INVENTION
  • [0010]
    The present invention solves the problems outlined above by describing devices and methods for securely affixing a localization wire to desired tissue in a patient's body, so that after the patient is moved from the imaging environment to the procedural environment, the practitioner will have assurance that the localization wire is still accurately placed. Additionally, devices and methods are described for ensuring that the distal end of a tissue acquisition instrument, such as a biopsy instrument, is securely affixed to a particular target area, such as a lesion, in a patient's body, thereby advantageously permitting the imaging environment to be uncoupled from the procedural environment so that expensive and often unavailable imaging equipment, such as stereotactic imaging equipment, need not be used.
  • [0011]
    More particularly, in one aspect of the invention a medical device is provided comprising a tube having a distal end, a proximal end, and a longitudinal axis, wherein the device is adapted for placement of the distal end thereof into a patient's body at a desired location. The medical device includes a fixation agent, which may comprise any one of a bonding agent, a mechanical fixation agent, or an electrosurgical coagulation element, disposed on the distal end thereof, which is adapted for affixing the distal end of the medical device at the desired location.
  • [0012]
    The medical device may comprise for example, a localization wire for use in connection with an open biopsy procedure. Alternatively, the device may comprise a tissue acquisition instrument, such as a biopsy instrument. In the preferred embodiment, the fixation agent is a bonding agent, comprising a surgical adhesive, glue, or solvent.
  • [0013]
    In another aspect of the invention, a tissue acquisition instrument is provided for retrieving body tissue, having a longitudinal axis and which comprises a distal end adapted for entry into a patient's body, a cutting element disposed on the instrument for cutting surrounding tissue, and structure disposed on the distal end for securing the tissue acquisition instrument at a predetermined desired location, in order to ensure that the tissue acquisition instrument remains in place during a tissue acquisition procedure so that desired tissue is properly acquired.
  • [0014]
    In yet another aspect of the invention, a method of performing a medical procedure is provided, using a medical device comprising a tube having a distal end, a proximal end, and a longitudinal axis. The method first comprises the step of placing the distal end of the tube in a patient's body, so that the distal end is disposed in a desired tissue location. Then, a bonding agent is dispensed for the tube into tissue surrounding the distal end, so that the distal end of the tube becomes affixed to the desired tissue location.
  • [0015]
    In still another aspect of the invention, a method is provided for performing a tissue acquisition procedure using a tissue acquisition instrument having a distal end, a proximal end, a longitudinal axis, and a cutting element. In this method, the distal end of the instrument is placed into a patient's body, so that the distal end is disposed in a desired tissue location. Then, the distal end of the instrument is affixed to the desired tissue location, so that the instrument does not move relative to the desired tissue location during the tissue acquisition procedure. The cutting element is then actuated to acquire one or more tissue samples.
  • [0016]
    The invention, together with additional features and advantages thereof, may best be understood by reference to the following description taken in conjunction with the accompanying illustrative drawing.
  • BRIEF DESCRIPTION OF THE DRAWING
  • [0017]
    FIG. 1 is a schematic plan view of a first embodiment of the present invention, illustrating a catheter for a localization wire introduction and infusion system wherein an introducer needle for introducing the localization wire into a patient's body remains in place during securement of the localization wire to surrounding tissue using a bonding agent;
  • [0018]
    FIG. 2 is a schematic plan view of the introducer needle used in conjunction with the catheter of FIG. 1;
  • [0019]
    FIG. 3 is a schematic plan view of one embodiment of a localization wire which may be used in conjunction with the infusion system shown in FIGS. 1 and 2;
  • [0020]
    FIG. 3 a is a perspective view of the distal end of the embodiment shown in FIGS. 1-3, wherein the introducer needle is inserted through the lumen of the catheter;
  • [0021]
    FIG. 3 b is a perspective view of the distal end of the embodiment shown in FIGS. 1-3, wherein the introducer needle is inserted through the lumen of the catheter, and its position within the catheter lumen is shown in phantom for illustrative purposes;
  • [0022]
    FIG. 3 c is a perspective view similar to FIG. 3 a, wherein the localization wire is inserted through the lumen of the catheter;
  • [0023]
    FIG. 4 is a perspective view of a second embodiment of the present invention, illustrating a second embodiment of a localization wire introduction and infusion system, wherein an introducer needle for introducing the localization wire into a patient's body is removed during securement of the localization wire to surrounding tissue using a bonding agent;
  • [0024]
    FIG. 5 is schematic plan view of the catheter for the system illustrated in FIG. 4;
  • [0025]
    FIG. 6 is a schematic plan view of the introducer needle for the system illustrated in FIGS. 4 and 5;
  • [0026]
    FIG. 6 a is a perspective view of the distal end of the embodiment shown in FIGS. 4-6, wherein the localization wire is inserted through a lumen of the catheter;
  • [0027]
    FIG. 7 is a schematic plan view of a second embodiment of a localization wire which may be utilized in conjunction with either of the embodiments of FIGS. 1-3 or 4-6;
  • [0028]
    FIG. 8 is a schematic view in isolation illustrating one embodiment of the present invention for storing and releasing a bonding agent which is dispensed from a medical instrument for affixing the medical instrument to surrounding tissue in a patient's body;
  • [0029]
    FIG. 9 is a perspective view of a third embodiment of the present invention, illustrating a catheter which may be used as a localization wire and infusion system;
  • [0030]
    FIG. 10 is an enlarged perspective view of the distal end of the cannula illustrated in FIG. 9, showing in greater detail the perforations in the distal end for infusing a bonding agent to surrounding tissue;
  • [0031]
    FIG. 11 is a perspective view of a modified version of the embodiment shown in FIGS. 9 and 10, wherein the cannula is comprised of a braided polymer tubing and the interstices between the braids function as the infusion openings for infusing bonding agent to surrounding tissue;
  • [0032]
    FIG. 12 is a perspective view of another modified version of the embodiment shown in FIGS. 9 and 10, wherein the cannula is comprised of a coil and the interstices between expanded coils function as the infusion openings for infusing bonding agent to surrounding tissue;
  • [0033]
    FIG. 13 is a perspective view of a biopsy instrument constructed in accordance with the principles of the present invention;
  • [0034]
    FIG. 14 is a perspective view of a second modified embodiment of a biopsy instrument having an expandable Mallicot structure at its distal end for anchoring the instrument at a particular tissue site;
  • [0035]
    FIG. 15 is a perspective view of a third modified embodiment of a biopsy instrument having a modified expandable Mallicot structure at its distal end for anchoring the instrument at a particular tissue site;
  • [0036]
    FIG. 16 is a perspective view of a fourth modified embodiment of a biopsy instrument having an expandable linkage structure at its distal end for anchoring the instrument at a particular tissue site, wherein the linkage structure is shown in its retracted position;
  • [0037]
    FIG. 17 is a perspective view of the embodiment shown in FIG. 16, wherein the linkage structure is shown in its expanded position;
  • [0038]
    FIG. 18 is a perspective view of a fourth modified embodiment of a biopsy instrument having an extendable “bottle brush” structure at its distal end for anchoring the instrument at a particular tissue site;
  • [0039]
    FIG. 19 is a perspective view of a fifth modified embodiment of a biopsy instrument having a nitinol flap structure at its distal end, expandable upon retraction of a surrounding sleeve, for anchoring the instrument at a particular tissue site;
  • [0040]
    FIG. 20 is a perspective view of a sixth modified embodiment of a biopsy instrument having a rolled stent structure at its distal end which unrolls upon retraction of a surrounding sleeve, for anchoring the instrument at a particular tissue site;
  • [0041]
    FIG. 21 is a perspective view of a seventh modified embodiment of a biopsy instrument having expandable spiral wires at its distal end for anchoring the instrument at a particular tissue site; and
  • [0042]
    FIG. 22 is a perspective view of an eighth modified embodiment of a biopsy instrument having an expandable basket at its distal end for anchoring the instrument at a particular tissue site.
  • DETAILED DESCRIPTION OF THE INVENTION
  • [0043]
    Referring now more particularly to the drawings, FIGS. 1-3 c illustrate a first embodiment of the invention, wherein a medical instrument 10 (FIGS. 3 a-3 c) comprises a catheter 12 (FIGS. 1, 3 a-3 c), an introducer needle 14 (FIGS. 2, 3 a, and 3 b), and a localization wire 16 (FIGS. 3, 3 c). In this embodiment, which may be styled as a “needle in” infusion system, the introducer needle 14 comprises a sharp distal end 18, which is inserted through an entry hole 20 in the catheter 12 (FIG. 1), so that its tip 18 extends beyond the distal end 22 of the catheter 12, as shown in FIGS. 3 a and 3 b. The introducer needle 14 may include a stop 24 having an enlarged diameter, which is adapted to engage the distally tapering inner sidewall of the catheter 12 at a predetermined point, as generally shown particularly in FIG. 3 b, to ensure that the tip 18 properly extends beyond the distal end 22 of the catheter 12. The introducer needle 14 and catheter 12 together are then introduced into a patient's body (not shown), using known imaging techniques for guiding localization wires to the site of tissue to be excised (“target tissue”).
  • [0044]
    Once the catheter 12 and introducer needle 14 are in position relative to the target tissue, the introducer needle 14 is removed proximally from the catheter 12, and the localization wire 16 is inserted distally through the entry hole 20 and pushed distally through the lumen in the catheter 12, so that the distal end of the localization wire 16 extends distally of the distal end of the introducer needle and catheter, as shown in FIG. 3 b. Indicator marks 25 preferably assist the practitioner in ensuring that the localization wire is properly inserted to the required depth.
  • [0045]
    Localization wires such as the wire 16 typically include some-type of mechanical anchoring means, such as a barb or hook 26, for securing the distal end of the localization wire 16 in position behind the target tissue. However, this approach is often inadequate, as discussed supra in the Background portion of the specification, because the tissue to which the hook 26 becomes attached will often shift relative to the target tissue between the imaging step of the medical procedure, which is usually a biopsy, such as a breast biopsy, and the ensuing surgical step, which usually takes place in a different area of the hospital and requires transportation and resultant jostling of the patient from the radiology department to the operating room. The present invention, therefore, contemplates an advantageous additional step of employing a bonding agent, which may comprise any known material which is capable of creating a bond between the distal end of the medical instrument 10 and surrounding tissue. Once the localization wire is properly placed at the desired target tissue site, under imaging guidance, the bonding agent is dispensed from the distal end of the medical instrument to the surrounding tissue to create the desired bond. In the embodiment of FIGS. 1-3 a, a plurality of infusion ports 28 are disposed along the length of the distal end of the catheter 12. Any number of infusion ports (one or more) may be employed in order to optimize the flow of bonding agent to the tissue, and they are preferably staggered circumferentially about the catheter in order to evenly deliver bonding agent about the circumference of the instrument 10. Various delivery means may be employed as well. For example, in the illustrated embodiment, the catheter 12 comprises a proximal hub 30 (FIG. 1), including a stopcock 32 which is engageable with a syringe (not shown) containing the bonding agent. When the localization wire is properly positioned, the practitioner injects the bonding agent into the lumen (not shown) of the catheter using the syringe with sufficient pressure that it flows distally through the lumen and is infused into surrounding body tissue through the infusion ports 28. The resultant bonding of the distal end of the localization wire 16 to the surrounding target tissue ensures with much greater certainty than the use of mechanical attachment means alone, such as the hook 26, that the localization wire will be properly positioned when the surgical procedure commences, thereby improving the likelihood that the proper target tissue will be excised with a minimum incision and resultant trauma to the patient.
  • [0046]
    Preferred bonding agents include any known effective biocompatible bonding materials, such as surgical adhesives, including cyanoacrylate, fibrin glue, and solvents.
  • [0047]
    An alternative to injection of the bonding agent through the lumen of the medical instrument 10 is illustrated in FIG. 8. The bonding agent 33 may be stored in a rupturable container 34 which is disposed in the distal end of the medical instrument 10, adjacent to the infusion ports 28. When it is desired to release the bonding agent 33 through the infusion ports, a puncturing device 36 may be actuated by the practitioner to rupture the container 34. In the illustrated embodiment, the device 36 comprises a simple “spear” which is actuated distally to rupture the container, but it may alternatively comprise any suitable configuration for functioning equivalently. Additionally, it is within the scope of the invention to employ a chamber for containing the bonding agent which includes a valved port, wherein the valve is actuated to an open position by the practitioner to release the bonding agent. Various other embodiments for accomplishing this function, as would be known to one of ordinary skill in the art, are deemed to fall within the scope of the invention as well.
  • [0048]
    Once the localization wire is securely bonded to the surrounding tissue, the practitioner may withdraw the catheter and introducer needle assembly, leaving the localization wire in place to mark the target tissue for the ensuing surgical step in the biopsy or other medical procedure.
  • [0049]
    FIGS. 4-7 illustrate a second “localization wire” embodiment, wherein like elements to those shown in the first embodiment are designated by like reference numerals, succeeded by the letter “a”. This system may be styled as a “needle out” infusion system. In this embodiment, the catheter 12 a comprises a dual lumen extrusion, including first and second lumens 38 and 40, respectively (FIG. 6 a). The first lumen 38 accommodates the bonding agent, while the second lumen accommodates the localization wire. The catheter 12 a further includes a dual lumen proximal hub 42, which comprises a localization wire entry port 44 and a stopcock 32 a.
  • [0050]
    In operation, the introducer needle 14 a is disposed coaxially outside of the catheter 12 a, as illustrated in FIG. 4, and the instrument 10 a is inserted into the patient's body in known fashion, under conventional imaging guidance. The localization wire 16 a is inserted distally through the port 44, either before or after introduction of the instrument 10 a into the patient's body. As in the first embodiment, once the instrument 10 a is placed, the localization wire 16 a is advanced distally until the indicator marks 25 a indicate to the practitioner that the distal hook 26 a is distal of the distal end of the catheter 12 a and of the target lesion, as shown by the imaging equipment. The localization wires of FIGS. 3 and 7 may be used interchangeably in either of the two disclosed embodiments, and are substantially identical except that the localization wire 16 a includes filaments 46 near its distal end which provide additional surface area for bonding.
  • [0051]
    As in the previous embodiment, once the localization wire is in the proper position, bonding agent is injected into the catheter 12 a, preferably using a syringe which is engaged with the stopcock 32 a, so that the bonding agent flows distally through the first lumen 38 and is infused through the infusion ports 28 a. Again, the infusion ports may be disposed about the catheter, in rows offset by 90 degrees with respect to one another, or otherwise staggered so that the bonding agent is evenly disposed about the catheter. Alternatively, as in the previous embodiment, the bonding agent may be stored in the distal end of the instrument 10 a using an apparatus like that illustrated in FIG. 8. It is within the scope of this invention, as well, to store or inject two or more bonding agent compounds, comprising a reactant and a catalyst, at the injection site, and to mix the reactant and catalyst together at the appropriate time to catalyze a bonding agent.
  • [0052]
    Once the bonding agent has been injected, but before it has solidified, the catheter 12 a and introducer needle 14 a are withdrawn from the patient's body, leaving the localization wire in place.
  • [0053]
    Still a third embodiment, which functions in a manner equivalent to that of a localization wire is illustrated in FIGS. 9 and 10. In this embodiment, a catheter 48, which comprises a proximal hub 50, a distal end 52, and a lumen 54, is insertable into a patient's body using conventional image guidance techniques, so that the distal end 52 is disposed at a desired target tissue site. Once properly located, a bonding agent 33 is infused through one or more infusion ports 56 to surrounding target tissue, in order to bond the distal end of the catheter 48 to the surrounding tissue. Again, as in the previous embodiments, the bonding agent may be injected into the lumen 54 of the catheter through the proximal hub 50, or may alternatively be stored in the distal end 52 of the catheter and selectively released at the desired time.
  • [0054]
    FIGS. 11 and 12 illustrate two alternative embodiments for the outer tube 58 of the catheter in any of the foregoing embodiments. In FIG. I 1, the tube 58 comprises a stainless steel braid, the proximal end 60 of which is encapsulated by a polymer, such as polyamide, and the distal end 62 of which is exposed. The exposed distal end is preferably approximately 1-2 centimeter (cm) in length, though it may be longer or shorter if desired. In operation, interstices 64 between bands 66 of the exposed braided portion 62 function as openings for permitting infusion of bonding agent to surrounding tissue, instead of the infusion ports disclosed in the preceding embodiments. If the exposed braided portion is expanded, the interstices will be enlarged and will permit the flow of more bonding agent therethrough.
  • [0055]
    In a manner in some respects similar to the embodiment of FIG. 11, the FIG. 12 embodiment comprises an outer tube 58 having a sleeve 68 surrounding a coil 70 of suitable material. In the distal end of the tube 58, the coil 70 may be stretched to create interstices 72 between bands 74 of the coil. Bonding material may be infused, as desired, outwardly through the interstices 72 of the expanded coil, and then through holes 76 in the sleeve 68 to surrounding tissue. Alternatively, the sleeve could be retracted to expose the coil, in which case the sleeve holes 76 would be unnecessary.
  • [0056]
    FIG. 13 illustrates the distal end of a medical instrument 78 which is shown and described in co-pending application Ser. No. 09/057,303, commonly assigned with the present application and expressly incorporated by reference herein. The instrument 78 comprises a tissue acquisition or biopsy instrument and preferably includes a tip 80 having an electrosurgical element 82 for entering tissue, and a shaft 84, on which is disposed a radially extendable and retractable cutting element or wire 86. The cutting element 86 is preferably energized by RF energy provided by an electrosurgical generator.
  • [0057]
    In operation, the instrument 78 is moved axially to a position wherein the distal tip 80 is preferably distal to a target lesion or tissue to be removed, using a suitable imaging technique; In the prior art, such imaging techniques for biopsy procedures and the like typically include the use of a stereotactic or sonographic imaging system, both of which are relatively expensive and not always available in an average community hospital. This approach is designed to combine the imaging and cutting steps so that both occur simultaneously. For example, in the case of a breast biopsy procedure, the breast is clamped in order to effectively utilize the imaging equipment, after which the instrument is inserted into the breast under imaging guidance to the lesion location. Then, under continued imaging guidance, the cutting element is actuated and the target tissue removed.
  • [0058]
    However, an important advantage of the present invention is the ability to “uncouple” the imaging environment from the procedural environment in a typical surgical or biopsy procedure, and the resultant important ability to utilize unmodified mammography equipment, readily available in most hospitals, to position the distal end of the instrument during the imaging step, rather than expensive and specialized stereotactic equipment. Then, the procedural step may occur later, in another area of the hospital. In the case of breast biopsies, this “uncoupling” also permits the patient's breast to be unclamped for the procedural step, resulting in increased patient comfort and easier working conditions for the practitioner.
  • [0059]
    These advantages are made possible because the inventive apparatus and technique permits the securement of the distal end of the instrument to the target tissue or lesion with sufficient confidence that the patient may be moved to the procedural environment without fear of having it slip away from the target tissue. This securement is accomplished using a fixation agent, which preferably comprises a bonding agent like that disclosed in connection with the foregoing localization wire and catheter embodiments. In a manner similar to those embodiments, once the instrument is positioned in a desired position, the bonding agent is injected into a lumen of the instrument, or, alternatively, in a manner like that described supra, released from a container or chamber in the distal end of the instrument, so that it may be infused from one or more infusion ports 88 disposed on the distal end of the instrument. Preferably, the ports 88 are disposed on a bushing or sleeve 90 which has a linear slot 92 for permitting passage of the cutting element 86 as it is extended and retracted radially, and which is rotatable relative to the shaft 84. Thus, when the bonding agent is infused to the surrounding tissue, so that the bushing 90 is affixed in place relative to the surrounding tissue, the cutting element 86 will still be rotatable on the underlying shaft 84 in order to permit circumferential cutting of tissue, as desired, during the later procedural step. Suitable care is taken that only a sufficient amount of bonding agent is dispensed to bond the bushing to surrounding tissue, and not the shaft or tip of the instrument, in order that the shaft and tip continue to be rotatable relative to the bushing.
  • [0060]
    Of course, the bushing 90 may be constructed in number of alternative ways, as will be apparent to those of ordinary skill in the art. For example, as shown in FIGS. 11 and 12, the bushing could be comprised of a braided or coil material, so that interstices between braids or coils thereof could function as the infusion openings.
  • [0061]
    Rather than using a bonding agent, a mechanical fixation agent may be utilized to secure the distal end of the instrument to surrounding tissue. For example, FIG. 14 illustrates an alternative embodiment to that of FIG. 13, wherein a mechanical fixation structure 94 is utilized to secure the distal end of the instrument to surrounding tissue, rather than a bonding agent. In this embodiment, wherein like elements to those of FIG. 13 are designated by like reference numerals, succeeded by the letter “b”, the mechanical fixation structure 94 comprises an expandable Mallicot structure, having a rotatable bushing 90 b and a plurality of expandable bands 96. Actuating pushrods 98, of which there are preferably four, arranged circumferentially 90 degrees apart, are provided to actuate the bands 96 between their expanded positions (as shown), in which they are positioned to anchor the distal tip 80 b to the desired tissue site, and their retracted positions.
  • [0062]
    FIG. 15 illustrates another modified embodiment which is similar to that of FIG. 14, and wherein like elements to those of FIG. 14 are designated by like reference numerals, succeeded by the letter “c”. The only difference between this embodiment and the FIG. 14 embodiment is that the bands 96 c are split at their centers, to form protruding portions 100, for the purpose of permitting further radial extension of each band and to also permit the protruding portions 100 to attach themselves to adjacent tissue.
  • [0063]
    FIGS. 16 and 17 schematically illustrate still another modified mechanical fixation structure 94 d, comprising a linkage, which may be substituted for the structures 94 and 94 c of FIGS. 14 and 15, respectively, wherein FIG. 16 illustrates the linkage in its retracted configuration and FIG. 17 illustrates it in its radially expanded configuration.
  • [0064]
    FIG. 18 schematically illustrates yet another modified mechanical fixation structure 94e, comprised of a plurality of radially retractable and extendable wires 102.
  • [0065]
    FIG. 19 schematically illustrates still another modified mechanical fixation structure 94 f, of the bone anchor type, comprised of a nitinol tube 104 and radially expandable flaps 106.
  • [0066]
    In FIG. 20, there is shown another modified mechanical fixation structure 94 g, comprised of a rolled stent which may be unrolled to expand radially and provide an anchoring function by axially retracting a sleeve 108.
  • [0067]
    FIG. 21 shows still another modified mechanical fixation structure 94 h comprised of a plurality of extendable wires 110.
  • [0068]
    FIG. 22 illustrates a modified mechanical fixation structure 94 i which comprises a radially expandable and retractable basket.
  • [0069]
    Any of the foregoing mechanical fixation structures may be interchangeably employed in the embodiments of FIGS. 14 and 15, and it is within the scope of this invention to also employ other mechanical fixation structures which are known conventionally for anchoring medical devices in the body.
  • [0070]
    Still another means for bonding the distal end of the instrument 78 to surrounding tissue, which is within the scope of the present invention, is to apply RF energy to the tissue, using an electrosurgical coagulation element. The electrosurgical coagulation element may comprise one of the existing electrosurgical elements 82 or 86, or preferably another coagulation element 112 (FIG. 13) which may be disposed on or near the bushing 90. Activation of the coagulation element 112 for a short interval coagulates the tissue surrounding the tissue, thereby bonding the bushing to the tissue. Alternatively, the element 112 could comprise a heating rod for cauterizing tissue, similar to the function of a branding iron, to produce the same type of bonding effect by “sticking” the cauterized tissue to the distal end of the instrument.
  • [0071]
    This approach may also be utilized in the localization wire embodiments illustrated in FIGS. 1-12, by employing an electrosurgical coagulation element on the distal end thereof, which is connected to a suitable-electrosurgical generator, or, alternatively, by employing an electrical heating element for cauterizing tissue.
  • [0072]
    While this invention has been described with respect to various specific examples and embodiments, it is to be understood that the invention is not limited thereto and that it can be variously practiced within the scope of the following claims.

Claims (63)

  1. 1. A medical device comprising a tube having a distal end, a proximal end, and a longitudinal axis, the device being adapted for placement of said distal end into a patient's body at a desired location, said medical device having a fixation agent disposed on said distal end, the fixation agent being adapted for affixing the distal end of said medical device at said desired location.
  2. 2-48. (canceled)
  3. 49. A medical device for securing a medical instrument to a desired location within a patient's body comprising:
    a. a shaft having a distal end, a proximal end, and a longitudinal axis, and having a distal tip configured for advancement within a patient's body to a desired location; and
    b. a fixation agent for fixing the distal end at the desired location which is selected from a group of fixation agents consisting of a bonding agent, an electrical heating agent, an electrosurgical cauterizing agent, and combinations thereof.
  4. 50. The medical device as recited in Clam 49, wherein the distal end of the device has at least one opening for dispensing bonding agent into the patient's body to fix the distal end at the desired location.
  5. 51. The medical device as recited in claim 50, wherein the bonding agent is a surgical adhesive.
  6. 52. The medical device as recited in claim 51, wherein the surgical adhesive is a cyanoacrylate.
  7. 53. The medical device as recited in claim 50, wherein the bonding agent is a fibrin glue.
  8. 54. The medical device as recited in claim 50, wherein the bonding agent is a solvent.
  9. 55. The medical device as recited in claim 50, wherein the tube has a braided outer wall.
  10. 56. The device of claim 55 wherein the braided outer wall has an interstice which forms at least in part the at least one opening for dispensing the bonding agent.
  11. 57. The medical device as recited in claim 50, wherein the shaft has an outer wall formed at least in part from a coil of material, which has at least one interstice for dispensing the bonding agent.
  12. 58. The medical device as recited in claim 50 having a tissue acquisition device with a longitudinal axis about which the medical device is rotatable, a cutting element disposed on the shaft for cutting surrounding tissue, and a bushing disposed on the shaft which has at least one opening and which is rotatable relative to the shaft, and wherein the bonding agent is dispensed through the at least one opening and affixes the bushing to the surrounding tissue, so that the instrument is secured to the desired location without preventing rotational movement thereof.
  13. 59. The medical device as recited in claim 49, wherein the fixation agent is an electrosurgical element disposed on the distal end of the shaft, which coagulates tissue surrounding the distal end of the shaft to affix tissue to the distal end of the shaft.
  14. 60. The medical device as recited in claim 49, wherein the fixation agent is an electrical heating element disposed on the shaft distal end which cauterizes tissue surrounding the shaft distal end and thereby causes the tissue to be affixed to the distal end of the shaft.
  15. 61. The medical device of claim 49, wherein the fixation agent is a, bonding agent selected from the group consisting of adhesives, solvents, and combinations thereof.
  16. 62. A medical device for securing medical instruments to a desired location in a patient's body comprising:
    a. a shaft having a distal end configured for advancement within a patient's body to a desired location, a proximal end, a localization wire, and a longitudinal axis;
    b. a fixation agent disposed on the distal end of the shaft which is adapted for affixing the distal end of the medical device at the desired location; and
    c. a catheter having a lumen through which the localization wire is introduced into the patient's body.
  17. 63. The medical device as recited in claim 62, wherein the fixation agent is a bonding agent, and the catheter has a second lumen which accommodates the bonding agent.
  18. 64. A medical device for securing medical instruments to a desired location in a patient's body comprising:
    a. a shaft having a distal end configured for advancement within a patient's body to a desired location, a proximal end, and a longitudinal axis and
    b. an expandable mechanical fixation agent which is configured for affixing the distal end of the shaft to the desired location.
  19. 65. The medical device as recited in claim 64, wherein the mechanical fixation agent is a Mallicot structure.
  20. 66. The medical device as recited in claim 64, wherein the mechanical fixation agent is a rolled stent and an axially movable sleeve, and the stent is exposed and unrolls to engage surrounding tissue and affix the distal end of the device when the sleeve is moved proximal to the stent.
  21. 67. The medical device as recited in claim 64, wherein the mechanical fixation agent is a radially expandable and retractable basket which is actuatable to extend outwardly into tissue surrounding the distal end of the device to engage the tissue and thereby anchor the distal end of the shaft to the desired location.
  22. 68. The medical device as recited-in claim 64, wherein the mechanical fixation agent is a wire.
  23. 69. The medical device as recited in claim 64, wherein the mechanical fixation agent is an anchor.
  24. 70. A tissue acquisition instrument for retrieving tissue at a body site comprising
    a. a longitudinal axis;
    b. a distal end with a distal tip configured for advancement within a patient's body;
    c. a cutting element having a contracted configuration for delivery to the body site and an expanded configuration for separating tissue from the body site;
    d. a lumen containing a bonding agent and at least one opening disposed at the distal end for dispensing the bonding agent to surrounding tissue; and
    e. a mechanical fixation element disposed proximal to the distal end which has an expanded configuration for securing the tissue acquisition instrument at a predetermined desired location, in order to insure that the tissue acquisition instrument remains in place during a tissue acquisition procedure and which has a fully retracted configuration with a transverse dimension of the bendable legs which is smaller than the expanded configuration.
  25. 71. The tissue acquisition instrument as recited in claim 70, wherein the instrument is rotatable about the longitudinal axis and wherein a bushing is disposed on the instrument which is rotatable relative to the instrument and which has an electrical heating element disposed on the bushing which cauterizes and bonds to the bushing when the electrical heating element is energized so that the instrument is secured to a location without preventing rotational movement thereof.
  26. 72. The tissue acquisition instrument as recited in claim 70, wherein the instrument is rotatable about the longitudinal axis and wherein the instrument has a bushing disposed on the instrument which is rotatable relative to the instrument and wherein the bonding agent dispensed through the at least one opening affixes the bushing to the surrounding tissue, so that the instrument is secured in a desired location without preventing rotational movement thereof.
  27. 73. The tissue acquisition instrument as recited in claim 70, wherein the bonding agent comprises a surgical adhesive.
  28. 74. The tissue acquisition instrument as recited in claim 73, wherein the surgical adhesive is a cyanoacrylate.
  29. 75. The tissue acquisition instrument as recited in claim 70, wherein the bonding agent is a fibrin glue.
  30. 76. The tissue acquisition as recited in claim 70 wherein the bonding agent is a solvent.
  31. 77. A tissue acquisition instrument for retrieving tissue at a body site comprising:
    a. a longitudinal axis;
    b. a distal end with a distal tip configured for advancement within a patient's body;
    c. a cutting element which has a contracted configuration for delivery to the body site and an expanded configuration for separating tissue from the body site;
    d. and a mechanical fixation element which is a Mallicot structure, which is disposed proximal to the distal end, which has an expanded configuration for securing the tissue acquisition instrument at a predetermined desired location, in order to insure that the tissue acquisition instrument remains in place during a tissue acquisition procedure and which has a fully retracted configuration with a transverse dimension of the bendable legs which is smaller than the expanded configuration.
  32. 78. The tissue acquisition instrument as recited in claim 77, wherein the mechanical fixation agent is a rolled stent and an axially movable sleeve and wherein the stent is exposed and unrolls to engage the surrounding tissue and affix to the distal end of the medical device when the sleeve is moved proximally to the stent.
  33. 79. The tissue acquisition instrument as recited in claim 77, wherein the tissue specimen has a transverse dimension and the Mallicot structure is configured to have a transverse dimension smaller than the transverse dimension of the tissue specimen.
  34. 80. The tissue acquisition instrument as recited in claim 77, wherein the cutting element has a transverse dimension and the Mallicot structure is configured to have a transverse dimension smaller than the transverse dimension of the cutting element.
  35. 81. A tissue acquisition instrument for retrieving a tissue specimen at a body site comprising:
    a. a longitudinal axis;
    b. a distal end with a distal tip configured for advancement within a patient's body;
    c. a cutting element which has a contracted configuration for delivery to the body site and an expanded configuration for separating tissue from the body site and
    d. a mechanical fixation element which is a radially expandable and retractable basket, which is disposed proximal to the distal end, which has an expanded configuration for securing the tissue acquisition instrument at a predetermined desired location, in order to insure that the tissue acquisition instrument remains in place during a tissue acquisition procedure and which has a fully retracted configuration with a transverse dimension which is smaller than the expanded configuration.
  36. 82. The tissue acquisition instrument as recited in claim 81, wherein the tissue specimen has a transverse dimension and the radially expandable and retractable basket is configured to have a transverse dimension smaller than the transverse dimension of the tissue specimen.
  37. 83. The tissue acquisition instrument as recited in claim 81, wherein the cutting element has a transverse dimension and the radially expandable and retractable basket is configured to have a transverse dimension smaller than the transverse dimension of the cutting element.
  38. 84. A tissue acquisition instrument for retrieving tissue at a body site comprising:
    a. a longitudinal axis;
    b. a distal end with a distal tip configured for advancement within a patient's body;
    c. a-cutting element which has a contracted configuration for delivery to the body site and an expanded configuration for separating tissue from the body site;
    d. a mechanical fixation element disposed proximal to the distal end which has an expanded configuration for securing the tissue acquisition instrument at a predetermined desired location, in order to insure that the tissue acquisition instrument remains in place during a tissue acquisition procedure and which has a contracted configuration with a transverse dimension which is smaller than the expanded configuration for delivery to a target site; and
    e. a bushing which is disposed on the instrument, which is rotatable relative to the instrument, and which has an electrosurgical element disposed on the bushing which coagulates and bonds surrounding tissue to the bushing when the electrosurgical element is energized so that the instrument is secured in a desired location without preventing movement thereof.
  39. 85. A tissue acquisition instrument for retrieving tissue at a body site comprising:
    a. an elongated shaft having a distal portion, a proximal portion and a longitudinal axis;
    b. a distal end with a distal tip configured for advancement within a patient's body;
    c. a cutting element which has a contracted configuration for delivery to the body site and an expanded configuration for separating tissue from the body site; and
    d. a mechanical fixation element disposed proximal to the distal end which has an expanded configuration for securing the tissue acquisition instrument at a predetermined desired location, in order to insure that the tissue acquisition instrument remains in place during a tissue acquisition procedure, and which has a fully retracted configuration with a transverse dimension which is smaller than the expanded configuration and a hinged linkage configured to have a transverse dimension smaller than a transverse dimension of a tissue specimen.
  40. 86. A method for performing a tissue acquisition procedure comprising the steps of:
    a.) providing a tissue acquisition instrument having a distal end, a proximal end, a longitudinal axis, and a cutting element;
    b) placing the distal end of the instrument in a patient's body, so that the distal end is disposed in a desired tissue location and
    c) affixing the distal end of the instrument to the desired tissue location by performing a step selected from the group consisting of dispensing a bonding agent from the distal end into surrounding tissue, activating an electrosurgical element, activating an electrical heating element, and combinations thereof.
  41. 87. The method as recited in claim 86, wherein the step of affixing the distal end of the instrument is performed by dispensing a bonding agent from the distal end into surrounding tissue.
  42. 88. The method of claim 87, wherein the bonding agent is selected from the group consisting of adhesives, solvents, and combinations thereof.
  43. 89. The method as recited in claim 86, wherein the step of affixing the distal end of the instrument is performed by activating an electrosurgical element and operating it to coagulate tissue surrounding the distal end of the instrument, to an extent that the tissue bonds to the instrument distal end.
  44. 90. The method as recited in claim 86, wherein the step of affixing the distal end of the instrument is performed by activating an electrical heating element and operating it to cauterize tissue surrounding the distal end of the instrument, to an extent that the tissue bonds to the instrument distal end.
  45. 91. A biopsy device for separating a tissue specimen from a target site within a patient, comprising:
    a. an elongated shaft having a distal shaft portion, a proximal shaft portion, a tissue penetrating distal tip and a longitudinal axis;
    b. a radially expandable, longitudinally oriented tissue cutting component which is secured to the distal shaft portion proximal to the distal tip, which has a distal end and a proximal end and which has a contracted configuration for delivery to the target site and an expanded configuration for cutting the tissue specimen from supporting tissue at the target site; and
    c. a tissue fixation component disposed on the elongated shaft between the proximal and distal ends of the tissue cutting component to be fixed to the tissue specimen.
  46. 92. The device of claim 91 wherein the tissue fixation component includes a bushing which is disposed on the shaft between the ends of the tissue cutting component, which has at least one discharge opening and which is rotatable relative to the shaft, and wherein a bonding agent is dispensed through the at least one opening to affix the bushing to the tissue specimen.
  47. 93. The device of claim 91, wherein the bonding agent is at least in part a surgical adhesive.
  48. 94. The device of claim 93 wherein the surgical adhesive is at least in part a cyanoacrylate.
  49. 95. The device of claim 91, wherein the bonding agent is at least in part a fibrin glue.
  50. 96. The device of claim 91 wherein the bonding agent is at least in part a solvent.
  51. 97. The device of claim 91, wherein the tissue fixation component includes a Mallicot structure.
  52. 98. The device of claim 91, wherein the tissue fixation component includes an expandable stent.
  53. 99. The device of claim. 98 wherein an axially movable sleeve is disposed about the expandable stent, and removal of the sleeve allows the stent to expand and thereby be fixed to the tissue specimen.
  54. 100. The device of claim 91, wherein the tissue fixation component includes a radially expandable and retractable basket.
  55. 101. The device of claim 91 wherein the tissue fixation component has at least one expandable band.
  56. 102. The device of claim 101 wherein the at least one expandable band is split at its center to form a tissue engaging protruding portion.
  57. 103. The device of claim 102 wherein the tissue engaging protruding portion extends distally.
  58. 104. The device of claim 103 wherein the tissue engaging protruding portion extends proximally.
  59. 105. The device of claim 101 wherein the tissue fixation component has a plurality of protruding portions, with at least one protruding portion extending distal and at least one protruding portion extending proximal.
  60. 106. The device of claim 105 wherein the protruding portions are part of split bands.
  61. 107. The device of claim 91 wherein the penetrating distal tip has an electrosurgical tissue cutting element.
  62. 108. The device of claim 107 wherein the electrosurgical tissue cutting element lies in a plane perpendicular to the longitudinal axis of the elongated shaft.
  63. 109. The device of claim 107 wherein the electrosurgical tissue cutting element is configured for connection to a RF power source.
US11303154 1998-03-03 2005-12-15 Methods and apparatus for securing medical instruments to desired locations in a patient's body Abandoned US20060094983A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US7697398 true 1998-03-03 1998-03-03
US09057303 US6331166B1 (en) 1998-03-03 1998-04-08 Breast biopsy system and method
US09146185 US6540693B2 (en) 1998-03-03 1998-09-01 Methods and apparatus for securing medical instruments to desired locations in a patients body
US10010213 US7264596B2 (en) 1998-03-03 2001-12-04 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US11303154 US20060094983A1 (en) 1998-03-03 2005-12-15 Methods and apparatus for securing medical instruments to desired locations in a patient's body

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11303154 US20060094983A1 (en) 1998-03-03 2005-12-15 Methods and apparatus for securing medical instruments to desired locations in a patient's body

Publications (1)

Publication Number Publication Date
US20060094983A1 true true US20060094983A1 (en) 2006-05-04

Family

ID=22516198

Family Applications (8)

Application Number Title Priority Date Filing Date
US09146185 Expired - Lifetime US6540693B2 (en) 1998-03-03 1998-09-01 Methods and apparatus for securing medical instruments to desired locations in a patients body
US10004987 Active 2019-01-14 US6958044B2 (en) 1998-03-03 2001-12-04 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US10010213 Active 2019-08-03 US7264596B2 (en) 1998-03-03 2001-12-04 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US11059992 Active 2022-03-16 US8229553B2 (en) 1998-03-03 2005-02-17 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US11179277 Expired - Lifetime US7329228B2 (en) 1998-03-03 2005-07-11 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US11303154 Abandoned US20060094983A1 (en) 1998-03-03 2005-12-15 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US13543309 Active 2020-06-24 US9216012B2 (en) 1998-03-03 2012-07-06 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US14939320 Pending US20160058433A1 (en) 1998-03-03 2015-11-12 Methods and apparatus for securing medical instruments to desired locations in a patient's body

Family Applications Before (5)

Application Number Title Priority Date Filing Date
US09146185 Expired - Lifetime US6540693B2 (en) 1998-03-03 1998-09-01 Methods and apparatus for securing medical instruments to desired locations in a patients body
US10004987 Active 2019-01-14 US6958044B2 (en) 1998-03-03 2001-12-04 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US10010213 Active 2019-08-03 US7264596B2 (en) 1998-03-03 2001-12-04 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US11059992 Active 2022-03-16 US8229553B2 (en) 1998-03-03 2005-02-17 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US11179277 Expired - Lifetime US7329228B2 (en) 1998-03-03 2005-07-11 Methods and apparatus for securing medical instruments to desired locations in a patient's body

Family Applications After (2)

Application Number Title Priority Date Filing Date
US13543309 Active 2020-06-24 US9216012B2 (en) 1998-03-03 2012-07-06 Methods and apparatus for securing medical instruments to desired locations in a patient's body
US14939320 Pending US20160058433A1 (en) 1998-03-03 2015-11-12 Methods and apparatus for securing medical instruments to desired locations in a patient's body

Country Status (5)

Country Link
US (8) US6540693B2 (en)
EP (1) EP1109496B1 (en)
JP (1) JP2002523170A (en)
CA (1) CA2341528C (en)
WO (1) WO2000012009A8 (en)

Cited By (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040102671A1 (en) * 2001-11-02 2004-05-27 Terwilliger Richard A. Delivery system and method for interstitial radiation therapy using seed strands constructed with preformed strand housing
US20060074270A1 (en) * 2003-05-13 2006-04-06 World Wide Medical Technologies, Llc Delivery system and method for interstitial radiation therapy using seed strands with custom end spacing
US20060217635A1 (en) * 2005-03-24 2006-09-28 Mccombs Elizabeth S Biopsy device marker deployment
US20070021642A1 (en) * 2005-07-22 2007-01-25 Worldwide Medical Technologies Llc Devices to resist migration and rotation of implants used in brachytherapy and other radiation therapy
US20070197971A1 (en) * 2006-02-22 2007-08-23 Krueger John A Curable material delivery device with a rotatable supply section
US20070197854A1 (en) * 2006-01-27 2007-08-23 Circulite, Inc. Heart assist system
US20070265488A1 (en) * 2006-05-09 2007-11-15 Worldwide Medical Technologies Llc After-loader for positioning implants for needle delivery in brachytherapy and other radiation therapy
US20080076960A1 (en) * 2006-08-30 2008-03-27 Circulite, Inc. Cannula insertion devices, systems, and methods including a compressible member
US20080076959A1 (en) * 2006-08-30 2008-03-27 Circulite, Inc. Devices, methods and systems for establishing supplemental blood flow in the circulatory system
US20080269540A1 (en) * 2007-04-27 2008-10-30 Worldwide Medical Technologies Llc Seed cartridge adaptor and methods for use therewith
US20090023975A1 (en) * 2007-07-19 2009-01-22 Circulite, Inc. Cannula for heart chamber implantation and related systems and methods
US20090088730A1 (en) * 2007-09-28 2009-04-02 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US20090088695A1 (en) * 2007-09-28 2009-04-02 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US20090171137A1 (en) * 2006-09-14 2009-07-02 Circulite, Inc. Intravascular blood pump and catheter
US20090182188A1 (en) * 2006-08-30 2009-07-16 Circulite, Inc. Devices, methods and systems for establishing supplemental blood flow in the circulatory system
US20090216063A1 (en) * 2008-01-29 2009-08-27 Biocompatibles Uk Limited Bio-absorbable brachytherapy strands
US20090318950A1 (en) * 2006-07-24 2009-12-24 Yossi Gross Fibroid treatment apparatus and method
US20100121130A1 (en) * 2001-11-02 2010-05-13 Biocompatibles Uk Limited Delivery system and method for interstitial radiation therapy
US20100204678A1 (en) * 2009-02-12 2010-08-12 Mir Imran Skin penetrating device and method for subcutaneous solid drug delivery
US20100249490A1 (en) * 2009-03-27 2010-09-30 Circulite, Inc. Transseptal cannula device, coaxial balloon delivery device, and methods of using the same
US20100249491A1 (en) * 2009-03-27 2010-09-30 Circulite, Inc. Two-piece transseptal cannula, delivery system, and method of delivery
WO2010093837A3 (en) * 2009-02-11 2010-12-16 Tendyne Medical, Inc. Percutaneous mitral annular stitch to decrease mitral regurgitation
US7874976B1 (en) 2006-09-07 2011-01-25 Biocompatibles Uk Limited Echogenic strands and spacers therein
US20110022073A1 (en) * 2009-07-27 2011-01-27 Fibro Control, Inc. Balloon with rigid tube for occluding the uterine artery
US7878964B1 (en) 2006-09-07 2011-02-01 Biocompatibles Uk Limited Echogenic spacers and strands
US20110040281A1 (en) * 2009-08-14 2011-02-17 White Steven B Integrated vascular delivery system
US20110054487A1 (en) * 2009-09-02 2011-03-03 Circulite, Inc. Coaxial transseptal guide-wire and needle assembly
US20110112353A1 (en) * 2009-11-09 2011-05-12 Circulite, Inc. Bifurcated outflow cannulae
US20110118668A1 (en) * 2009-11-13 2011-05-19 Circulite, Inc. Cannula stabilizer
US20110196191A1 (en) * 2010-02-11 2011-08-11 Circulite, Inc. Cannula lined with tissue in-growth material and method of using the same
US20110251516A1 (en) * 2010-04-13 2011-10-13 Thomas Doerr Implant and applicator
US8066627B2 (en) 2001-11-02 2011-11-29 Biocompatibles Uk Limited Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings
US8187159B2 (en) 2005-07-22 2012-05-29 Biocompatibles, UK Therapeutic member including a rail used in brachytherapy and other radiation therapy
KR101212412B1 (en) 2010-08-24 2012-12-13 사회복지법인 삼성생명공익재단 Needle for Vats
US8343029B2 (en) 2007-10-24 2013-01-01 Circulite, Inc. Transseptal cannula, tip, delivery system, and method
US8439892B2 (en) 2007-09-28 2013-05-14 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US8470294B2 (en) 2000-11-16 2013-06-25 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
WO2014009420A1 (en) * 2012-07-12 2014-01-16 Bowa-Electronic Gmbh & Co. Kg Instrument for cutting body tissue
WO2014055686A1 (en) * 2012-10-02 2014-04-10 Wallace Robert F Implant insertion system
US8771230B2 (en) 2010-05-19 2014-07-08 Tangent Medical Technologies, Llc Integrated vascular delivery system
US8814833B2 (en) 2010-05-19 2014-08-26 Tangent Medical Technologies Llc Safety needle system operable with a medical device
US9078749B2 (en) 2007-09-13 2015-07-14 Georg Lutter Truncated cone heart valve stent
US9216012B2 (en) 1998-09-01 2015-12-22 Senorx, Inc Methods and apparatus for securing medical instruments to desired locations in a patient's body
US9480559B2 (en) 2011-08-11 2016-11-01 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US9510809B2 (en) 1999-01-27 2016-12-06 Senorx, Inc. Tissue specimen isolating and damaging device and method
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
US9597181B2 (en) 2013-06-25 2017-03-21 Tendyne Holdings, Inc. Thrombus management and structural compliance features for prosthetic heart valves
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
US9675454B2 (en) 2012-07-30 2017-06-13 Tendyne Holdings, Inc. Delivery systems and methods for transcatheter prosthetic valves
US9750866B2 (en) 2010-02-11 2017-09-05 Circulite, Inc. Cannula lined with tissue in-growth material
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
US9895221B2 (en) 2012-07-28 2018-02-20 Tendyne Holdings, Inc. Multi-component designs for heart valve retrieval device, sealing structures and stent assembly

Families Citing this family (146)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852487B1 (en) * 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US20020058882A1 (en) * 1998-06-22 2002-05-16 Artemis Medical, Incorporated Biopsy localization method and device
JP4255208B2 (en) * 1997-07-24 2009-04-15 レックス メディカル リミテッド パートナーシップ Apparatus for ablating a subcutaneous target tissue mass was
US6626903B2 (en) 1997-07-24 2003-09-30 Rex Medical, L.P. Surgical biopsy device
US8668737B2 (en) 1997-10-10 2014-03-11 Senorx, Inc. Tissue marking implant
DE69839888D1 (en) * 1997-11-12 2008-09-25 Genesis Technologies Llc A device for removing occlusions in biological passages
US9498604B2 (en) 1997-11-12 2016-11-22 Genesis Technologies Llc Medical device and method
US20100030256A1 (en) 1997-11-12 2010-02-04 Genesis Technologies Llc Medical Devices and Methods
US6599312B2 (en) 1998-03-24 2003-07-29 Innercool Therapies, Inc. Isolated selective organ cooling apparatus
US6312452B1 (en) 1998-01-23 2001-11-06 Innercool Therapies, Inc. Selective organ cooling catheter with guidewire apparatus and temperature-monitoring device
EP1054634A4 (en) 1998-02-10 2006-03-29 Artemis Medical Inc Entrapping apparatus and method for use
US6602265B2 (en) * 1998-02-10 2003-08-05 Artemis Medical, Inc. Tissue separation medical device and method
US6530923B1 (en) * 1998-02-10 2003-03-11 Artemis Medical, Inc. Tissue removal methods and apparatus
US6602204B2 (en) 1998-02-10 2003-08-05 Artemis Medical, Inc Intraoperative tissue treatment methods
US20040010206A1 (en) * 1998-02-10 2004-01-15 Dubrul William R. Intraoperative tissue treatment methods
US6997885B2 (en) * 1998-04-08 2006-02-14 Senorx, Inc. Dilation devices and methods for removing tissue specimens
US6540695B1 (en) * 1998-04-08 2003-04-01 Senorx, Inc. Biopsy anchor device with cutter
US6638234B2 (en) * 1998-03-03 2003-10-28 Senorx, Inc. Sentinel node location and biopsy
US6905494B2 (en) 1998-03-31 2005-06-14 Innercool Therapies, Inc. Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection
US6363940B1 (en) 1998-05-14 2002-04-02 Calypso Medical Technologies, Inc. System and method for bracketing and removing tissue
US6270464B1 (en) * 1998-06-22 2001-08-07 Artemis Medical, Inc. Biopsy localization method and device
US6179860B1 (en) 1998-08-19 2001-01-30 Artemis Medical, Inc. Target tissue localization device and method
US6022362A (en) 1998-09-03 2000-02-08 Rubicor Medical, Inc. Excisional biopsy devices and methods
US6440147B1 (en) 1998-09-03 2002-08-27 Rubicor Medical, Inc. Excisional biopsy devices and methods
US6862470B2 (en) 1999-02-02 2005-03-01 Senorx, Inc. Cavity-filling biopsy site markers
US8361082B2 (en) 1999-02-02 2013-01-29 Senorx, Inc. Marker delivery device with releasable plug
US9820824B2 (en) 1999-02-02 2017-11-21 Senorx, Inc. Deployment of polysaccharide markers for treating a site within a patent
CA2775170C (en) 2000-11-20 2017-09-05 Senorx, Inc. An intracorporeal marker delivery system for marking a tissue site
US6306132B1 (en) 1999-06-17 2001-10-23 Vivant Medical Modular biopsy and microwave ablation needle delivery apparatus adapted to in situ assembly and method of use
US6575991B1 (en) 1999-06-17 2003-06-10 Inrad, Inc. Apparatus for the percutaneous marking of a lesion
US20040097996A1 (en) 1999-10-05 2004-05-20 Omnisonics Medical Technologies, Inc. Apparatus and method of removing occlusions using an ultrasonic medical device operating in a transverse mode
US20040158150A1 (en) * 1999-10-05 2004-08-12 Omnisonics Medical Technologies, Inc. Apparatus and method for an ultrasonic medical device for tissue remodeling
US6660013B2 (en) * 1999-10-05 2003-12-09 Omnisonics Medical Technologies, Inc. Apparatus for removing plaque from blood vessels using ultrasonic energy
US6564806B1 (en) 2000-02-18 2003-05-20 Thomas J. Fogarty Device for accurately marking tissue
EP1259155B1 (en) 2000-02-18 2010-12-08 Fogarty, Thomas J. Improved device for accurately marking tissue
US6722371B1 (en) 2000-02-18 2004-04-20 Thomas J. Fogarty Device for accurately marking tissue
US6494844B1 (en) 2000-06-21 2002-12-17 Sanarus Medical, Inc. Device for biopsy and treatment of breast tumors
US6482184B1 (en) * 2000-09-29 2002-11-19 Advanced Infusion, Inc. Attachable catheter
US6540694B1 (en) 2000-10-16 2003-04-01 Sanarus Medical, Inc. Device for biopsy tumors
WO2002032318A1 (en) 2000-10-16 2002-04-25 Sanarus Medical, Inc. Device for biopsy of tumors
US20030204188A1 (en) * 2001-11-07 2003-10-30 Artemis Medical, Inc. Tissue separating and localizing catheter assembly
WO2002076281A3 (en) * 2000-11-07 2003-06-19 Artemis Medical Inc Tissue separator assembly and method
US20020072739A1 (en) 2000-12-07 2002-06-13 Roberta Lee Methods and devices for radiofrequency electrosurgery
GB0120645D0 (en) 2001-08-24 2001-10-17 Smiths Group Plc Medico-surgical devices
US6589240B2 (en) 2001-08-28 2003-07-08 Rex Medical, L.P. Tissue biopsy apparatus with collapsible cutter
US6623437B2 (en) 2001-08-28 2003-09-23 Rex Medical, L.P. Tissue biopsy apparatus
CN100502806C (en) 2001-11-09 2009-06-24 诺沃斯特公司 Balloon catheter with non-deployable stent
US20030163147A1 (en) * 2002-02-22 2003-08-28 Rabiner Robert A. Apparatus and method for using a vascular introducer with an ultrasonic probe
US20030163143A1 (en) * 2002-02-26 2003-08-28 Akio Wakabayashi Apparatus and method for suturing in restricted space
US7197363B2 (en) 2002-04-16 2007-03-27 Vivant Medical, Inc. Microwave antenna having a curved configuration
US6752767B2 (en) 2002-04-16 2004-06-22 Vivant Medical, Inc. Localization element with energized tip
US7651505B2 (en) 2002-06-17 2010-01-26 Senorx, Inc. Plugged tip delivery for marker placement
US7044956B2 (en) 2002-07-03 2006-05-16 Rubicor Medical, Inc. Methods and devices for cutting and collecting soft tissue
WO2004020024A1 (en) * 2002-08-30 2004-03-11 Inrad, Inc. Localizing needle with fluid delivery
US7931658B2 (en) 2002-09-20 2011-04-26 Interrad Medical, Inc. Temporary retention device
US6936014B2 (en) 2002-10-16 2005-08-30 Rubicor Medical, Inc. Devices and methods for performing procedures on a breast
US7029451B2 (en) 2002-11-06 2006-04-18 Rubicor Medical, Inc. Excisional devices having selective cutting and atraumatic configurations and methods of using same
EP2110094B1 (en) 2002-11-18 2012-06-27 Bard Peripheral Vascular, Inc. Apparatus and method for implanting a preloaded localization wire
US20060036158A1 (en) 2003-11-17 2006-02-16 Inrad, Inc. Self-contained, self-piercing, side-expelling marking apparatus
US7289839B2 (en) 2002-12-30 2007-10-30 Calypso Medical Technologies, Inc. Implantable marker with a leadless signal transmitter compatible for use in magnetic resonance devices
US6889833B2 (en) 2002-12-30 2005-05-10 Calypso Medical Technologies, Inc. Packaged systems for implanting markers in a patient and methods for manufacturing and using such systems
US8080026B2 (en) 2003-01-21 2011-12-20 Angioscore, Inc. Apparatus and methods for treating hardened vascular lesions
US9408592B2 (en) 2003-12-23 2016-08-09 Senorx, Inc. Biopsy device with aperture orientation and improved tip
US7189206B2 (en) 2003-02-24 2007-03-13 Senorx, Inc. Biopsy device with inner cutter
US7534242B2 (en) 2003-02-25 2009-05-19 Artemis Medical, Inc. Tissue separating catheter assembly and method
US6994677B1 (en) 2003-02-25 2006-02-07 Artemis Medical, Inc. Tissue localizing and separating assembly
US7983734B2 (en) 2003-05-23 2011-07-19 Senorx, Inc. Fibrous marker and intracorporeal delivery thereof
US7122011B2 (en) 2003-06-18 2006-10-17 Rubicor Medical, Inc. Methods and devices for cutting and collecting soft tissue
US7066879B2 (en) * 2003-07-15 2006-06-27 The Trustees Of Columbia University In The City Of New York Insertable device and system for minimal access procedure
US20090012530A1 (en) * 2003-07-15 2009-01-08 Fowler Dennis L Insertable Device and System For Minimal Access Procedure
US7494473B2 (en) * 2003-07-30 2009-02-24 Intact Medical Corp. Electrical apparatus and system with improved tissue capture component
DE10345023A1 (en) * 2003-09-24 2005-04-21 Biotronik Gmbh & Co Kg Ablation catheter, comprising electrode holding elements in radial extended position when released
US7429259B2 (en) * 2003-12-02 2008-09-30 Cadeddu Jeffrey A Surgical anchor and system
US7273471B1 (en) 2003-12-23 2007-09-25 Advanced Cardiovascular Systems, Inc. Catheter balloon having a porous layer with ridges
US20050149072A1 (en) * 2003-12-31 2005-07-07 Devries Robert B. Devices and methods for tissue invagination
US7316709B2 (en) * 2004-01-13 2008-01-08 Advanced Cardiovascular Systems, Inc. Balloon catheter having a textured member for enhancing balloon or stent retention
US7794414B2 (en) * 2004-02-09 2010-09-14 Emigrant Bank, N.A. Apparatus and method for an ultrasonic medical device operating in torsional and transverse modes
US20050187514A1 (en) * 2004-02-09 2005-08-25 Omnisonics Medical Technologies, Inc. Apparatus and method for an ultrasonic medical device operating in a torsional mode
US7402140B2 (en) 2004-02-12 2008-07-22 Sanarus Medical, Inc. Rotational core biopsy device with liquid cryogen adhesion probe
US20050267488A1 (en) * 2004-05-13 2005-12-01 Omnisonics Medical Technologies, Inc. Apparatus and method for using an ultrasonic medical device to treat urolithiasis
US20050256410A1 (en) * 2004-05-14 2005-11-17 Omnisonics Medical Technologies, Inc. Apparatus and method for an ultrasonic probe capable of bending with aid of a balloon
CA2563827A1 (en) * 2004-06-09 2005-12-22 Ovalum Ltd. Blood vessel occlusion auger
US20060047253A1 (en) * 2004-08-24 2006-03-02 Hayman Michael H Needle assembly
US8409111B2 (en) * 2004-11-22 2013-04-02 Bard Peripheral Vascular, Inc. Removable localizing wire
US20060116610A1 (en) * 2004-11-30 2006-06-01 Omnisonics Medical Technologies, Inc. Apparatus and method for an ultrasonic medical device with variable frequency drive
GB0503730D0 (en) * 2005-02-23 2005-03-30 Medical Device Innovations Ltd Pneumothorax relief device
KR100766340B1 (en) 2005-03-28 2007-10-11 (주)메드멕스 Brush for liquid based cytology of cervix carcinoma
CA2602795A1 (en) * 2005-03-31 2006-10-05 Cytyc Corporation Internal biopsy marking
US20060259005A1 (en) 2005-05-11 2006-11-16 Angioscore, Inc. Methods and systems for delivering substances into luminal walls
US7556042B2 (en) * 2005-05-18 2009-07-07 Apmed Solutions, Inc. Methods and systems for tracheal access and ventilation
US20060260617A1 (en) * 2005-05-18 2006-11-23 Apmed Solutions, Inc. Methods and systems for tracheal access and ventilation
US9095325B2 (en) 2005-05-23 2015-08-04 Senorx, Inc. Tissue cutting member for a biopsy device
US8715294B2 (en) * 2005-08-05 2014-05-06 Ethicon Endo-Surgery, Inc. Gastric instrument sleeve to prevent cross contamination of stomach content and provide fixation and repeatable path
US7572236B2 (en) 2005-08-05 2009-08-11 Senorx, Inc. Biopsy device with fluid delivery to tissue specimens
US8317725B2 (en) 2005-08-05 2012-11-27 Senorx, Inc. Biopsy device with fluid delivery to tissue specimens
US7473232B2 (en) * 2006-02-24 2009-01-06 Boston Scientific Scimed, Inc. Obtaining a tissue sample
US8016794B2 (en) * 2006-03-09 2011-09-13 Interrad Medical, Inc. Anchor device and method
US20070219460A1 (en) * 2006-03-15 2007-09-20 Goldenberg Alec S Aspiration needles
US7691103B2 (en) * 2006-04-29 2010-04-06 Board Of Regents, The University Of Texas System Devices for use in transluminal and endoluminal surgery
US20070255303A1 (en) * 2006-05-01 2007-11-01 Ethicon Endo-Surgery, Inc. Integrated Guidewire Needle Knife Device
US20090216118A1 (en) 2007-07-26 2009-08-27 Senorx, Inc. Polysaccharide markers
US20080058846A1 (en) * 2006-08-31 2008-03-06 Khashayar Vosough Mechanical tissue morcellator
US8068921B2 (en) 2006-09-29 2011-11-29 Vivant Medical, Inc. Microwave antenna assembly and method of using the same
US20080140022A1 (en) * 2006-12-08 2008-06-12 Warsaw Orthopedic, Inc. Coated Cannula with Protective Tip for Insertion Into a Patient
EP2109409A4 (en) 2006-12-12 2012-11-21 Bard Inc C R Multiple imaging mode tissue marker
WO2008076973A3 (en) 2006-12-18 2008-08-14 Bard Inc C R Biopsy marker with in situ-generated imaging properties
US20080243082A1 (en) * 2007-03-30 2008-10-02 Closure Medical Corporation System for surgical drain fixation
WO2008137587A1 (en) * 2007-05-03 2008-11-13 I-Flow Corporation Apparatus for securing a catheter within an anatomy
US7753889B2 (en) 2007-06-15 2010-07-13 Interrad Medical, Inc. Anchor instrumentation and methods
US8292880B2 (en) 2007-11-27 2012-10-23 Vivant Medical, Inc. Targeted cooling of deployable microwave antenna
US8287538B2 (en) 2008-01-14 2012-10-16 Conventus Orthopaedics, Inc. Apparatus and methods for fracture repair
JP2009247696A (en) 2008-04-08 2009-10-29 Olympus Medical Systems Corp High-frequency treatment equipment
US8235948B2 (en) 2008-06-27 2012-08-07 Interrad Medical, Inc. System for anchoring medical devices
US8038653B2 (en) 2008-07-16 2011-10-18 Interrad Medical, Inc. Anchor systems and methods
US8328764B2 (en) * 2009-02-06 2012-12-11 Interrad Medical, Inc. System for anchoring medical devices
US20110087224A1 (en) * 2009-10-09 2011-04-14 Cadeddu Jeffrey A Magnetic surgical sled with variable arm
US20110178520A1 (en) 2010-01-15 2011-07-21 Kyle Taylor Rotary-rigid orthopaedic rod
CA2823873A1 (en) 2010-01-20 2011-07-28 Conventus Orthopaedics, Inc. Apparatus and methods for bone access and cavity preparation
JP2013521880A (en) * 2010-03-08 2013-06-13 コンベンタス オーソピディックス, インコーポレイテッド Apparatus and method for securing a bone implant
US8529466B2 (en) 2010-03-30 2013-09-10 Siteselect Medical Technologies, Inc. Tissue excision device with rotating stylet blades
EP2380604A1 (en) 2010-04-19 2011-10-26 InnoRa Gmbh Improved coating formulations for scoring or cutting balloon catheters
US9561094B2 (en) 2010-07-23 2017-02-07 Nfinium Vascular Technologies, Llc Devices and methods for treating venous diseases
US9078639B2 (en) 2010-08-03 2015-07-14 Biomet Biologics, Llc Bone marrow aspiration needle
US8728008B2 (en) * 2010-08-03 2014-05-20 Biomet Biologics, Llc Bone marrow aspiration needle
WO2012021976A1 (en) * 2010-08-20 2012-02-23 Queen's University At Kingston Probe for diagnosis and treatment of muscle contraction dysfunction
US8632559B2 (en) 2010-09-21 2014-01-21 Angioscore, Inc. Method and system for treating valve stenosis
US8343108B2 (en) 2010-09-29 2013-01-01 Interrad Medical, Inc. Systems and methods for anchoring medical devices
KR101211397B1 (en) 2010-11-18 2012-12-12 서울대학교병원 (분사무소) Wire position indication for thoracoscopic surgery for pulmonary nodules
US20120303018A1 (en) * 2011-05-23 2012-11-29 Tyco Healthcare Group Lp Tissue Dissectors
US8758264B2 (en) * 2011-06-29 2014-06-24 Cook Medical Technologies Llc Expandable device for full thickness biopsy
US8936576B2 (en) 2011-09-15 2015-01-20 Interrad Medical, Inc. System for anchoring medical devices
GB201120023D0 (en) * 2011-11-21 2012-01-04 Univ Dundee Radio frequency surgical probe
US8932263B2 (en) 2012-02-17 2015-01-13 Interrad Medical, Inc. Anchoring an intravenous cannula
US9314596B2 (en) 2012-10-11 2016-04-19 Interrad Medical, Inc. Systems and methods for anchoring medical devices
US9550043B2 (en) 2012-12-13 2017-01-24 Interrad Medical, Inc. Systems and methods for anchoring medical devices
US9415190B2 (en) 2013-02-13 2016-08-16 Interrad Medical, Inc. Systems and methods for anchoring medical devices
CN103142256B (en) * 2013-03-15 2015-02-25 江苏苏云医疗器材有限公司 Urethral sampler
US9381321B2 (en) 2013-05-03 2016-07-05 Interrad Medical, Inc. Systems and methods for anchoring medical devices
US20150057531A1 (en) * 2013-08-26 2015-02-26 Tera Dennis Soft tissue lesion excision guide
USD716450S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715942S1 (en) 2013-09-24 2014-10-21 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD715442S1 (en) 2013-09-24 2014-10-14 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
USD716451S1 (en) 2013-09-24 2014-10-28 C. R. Bard, Inc. Tissue marker for intracorporeal site identification
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
US9848947B2 (en) * 2013-12-11 2017-12-26 Boston Scientific Scimed, Inc. Devices and methods for prostate tissue ablation and/or resection
CN106236248A (en) * 2016-08-30 2016-12-21 苏州品诺维新医疗科技有限公司 Radio-frequency ablation device, system and method

Citations (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2032860A (en) * 1933-03-24 1936-03-03 Wappler Frederick Charles Method for electrosurgical treatment of tissue
US3805791A (en) * 1971-07-01 1974-04-23 K Seuberth Apparatus for the diathermic removal of growths
US3955578A (en) * 1974-12-23 1976-05-11 Cook Inc. Rotatable surgical snare
US4007732A (en) * 1975-09-02 1977-02-15 Robert Carl Kvavle Method for location and removal of soft tissue in human biopsy operations
US4202338A (en) * 1977-11-18 1980-05-13 Richard Wolf Gmbh Device for removing excrescences and polyps
US4294254A (en) * 1977-12-08 1981-10-13 Chamness Dale L Surgical apparatus
US4311143A (en) * 1978-10-12 1982-01-19 Olympus Optical Co., Ltd. Apparatus for resecting tissue inside the body cavity utilizing high-frequency currents
US4425908A (en) * 1981-10-22 1984-01-17 Beth Israel Hospital Blood clot filter
US4503855A (en) * 1981-12-31 1985-03-12 Harald Maslanka High frequency surgical snare electrode
US4576162A (en) * 1983-03-30 1986-03-18 Mccorkle Charles E Apparatus and method for separation of scar tissue in venous pathway
US4592356A (en) * 1984-09-28 1986-06-03 Pedro Gutierrez Localizing device
US4616656A (en) * 1985-03-19 1986-10-14 Nicholson James E Self-actuating breast lesion probe and method of using
US4638802A (en) * 1984-09-21 1987-01-27 Olympus Optical Co., Ltd. High frequency instrument for incision and excision
US4682606A (en) * 1986-02-03 1987-07-28 Decaprio Vincent H Localizing biopsy apparatus
US4718419A (en) * 1985-08-05 1988-01-12 Olympus Optical Co., Ltd. Snare assembly for endoscope
US4724836A (en) * 1985-01-08 1988-02-16 Olympus Optical Co., Ltd. High-frequency incision tool
US4774948A (en) * 1986-11-24 1988-10-04 Markham Charles W Marking and retraction needle having retrievable stylet
US4966583A (en) * 1989-02-03 1990-10-30 Elie Debbas Apparatus for locating a breast mass
US5007908A (en) * 1989-09-29 1991-04-16 Everest Medical Corporation Electrosurgical instrument having needle cutting electrode and spot-coag electrode
US5024617A (en) * 1989-03-03 1991-06-18 Wilson-Cook Medical, Inc. Sphincterotomy method and device having controlled bending and orientation
US5035696A (en) * 1990-02-02 1991-07-30 Everest Medical Corporation Electrosurgical instrument for conducting endoscopic retrograde sphincterotomy
US5047027A (en) * 1990-04-20 1991-09-10 Everest Medical Corporation Tumor resector
US5059197A (en) * 1989-04-15 1991-10-22 Urie Robert G Lesion location device
US5078716A (en) * 1990-05-11 1992-01-07 Doll Larry F Electrosurgical apparatus for resecting abnormal protruding growth
US5080660A (en) * 1990-05-11 1992-01-14 Applied Urology, Inc. Electrosurgical electrode
USRE33925E (en) * 1984-05-22 1992-05-12 Cordis Corporation Electrosurgical catheter aned method for vascular applications
US5111828A (en) * 1990-09-18 1992-05-12 Peb Biopsy Corporation Device for percutaneous excisional breast biopsy
USRE34056E (en) * 1989-07-31 1992-09-08 C.R. Bard, Inc. Tissue sampling device
US5158084A (en) * 1989-11-22 1992-10-27 Board Of Regents, The University Of Texas System Modified localization wire for excisional biopsy
US5158561A (en) * 1992-03-23 1992-10-27 Everest Medical Corporation Monopolar polypectomy snare with coagulation electrode
US5196007A (en) * 1991-06-07 1993-03-23 Alan Ellman Electrosurgical handpiece with activator
US5201741A (en) * 1990-07-24 1993-04-13 Andrew Surgical, Inc. Surgical snare with shape memory effect wire
US5207686A (en) * 1992-04-15 1993-05-04 Stuart Dolgin Surgical snare
US5210732A (en) * 1990-11-27 1993-05-11 Matsushita Electric Industrial Co., Ltd. Optical disk apparatus
US5221269A (en) * 1990-10-15 1993-06-22 Cook Incorporated Guide for localizing a nonpalpable breast lesion
US5224488A (en) * 1992-08-31 1993-07-06 Neuffer Francis H Biopsy needle with extendable cutting means
US5234426A (en) * 1989-06-15 1993-08-10 Research Corporation Technologies, Inc. Helical-tipped lesion localization needle device and method of using the same
US5312400A (en) * 1992-10-09 1994-05-17 Symbiosis Corporation Cautery probes for endoscopic electrosurgical suction-irrigation instrument
US5318564A (en) * 1992-05-01 1994-06-07 Hemostatic Surgery Corporation Bipolar surgical snare and methods of use
US5324288A (en) * 1991-04-30 1994-06-28 Utah Medical Products, Inc. Electrosurgical loop with a depth gauge
US5323768A (en) * 1991-04-22 1994-06-28 Olympus Optical Co., Ltd. Diathermic dissector with a bifurcation having substantially the same cross-sectional area as a lumen for guiding a wire
US5335671A (en) * 1989-11-06 1994-08-09 Mectra Labs, Inc. Tissue removal assembly with provision for an electro-cautery device
US5344420A (en) * 1991-02-13 1994-09-06 Applied Medical Resources Corporation Surgical trocar
US5353804A (en) * 1990-09-18 1994-10-11 Peb Biopsy Corporation Method and device for percutaneous exisional breast biopsy
US5380321A (en) * 1992-11-04 1995-01-10 Yoon; Inbae Shielded energy transmitting surgical instrument and methods therefor
US5395312A (en) * 1991-10-18 1995-03-07 Desai; Ashvin Surgical tool
US5395313A (en) * 1993-08-13 1995-03-07 Naves; Neil H. Reciprocating arthroscopic shaver
US5409004A (en) * 1993-06-11 1995-04-25 Cook Incorporated Localization device with radiopaque markings
US5415656A (en) * 1993-09-28 1995-05-16 American Medical Systems, Inc. Electrosurgical apparatus
US5417687A (en) * 1993-04-30 1995-05-23 Medical Scientific, Inc. Bipolar electrosurgical trocar
US5417697A (en) * 1993-07-07 1995-05-23 Wilk; Peter J. Polyp retrieval assembly with cauterization loop and suction web
US5423814A (en) * 1992-05-08 1995-06-13 Loma Linda University Medical Center Endoscopic bipolar coagulation device
US5423770A (en) * 1991-12-06 1995-06-13 Yoon; Inbae Automatic retractable safety penetrating instrument
US5437665A (en) * 1993-10-12 1995-08-01 Munro; Malcolm G. Electrosurgical loop electrode instrument for laparoscopic surgery
US5441503A (en) * 1988-09-24 1995-08-15 Considine; John Apparatus for removing tumors from hollow organs of the body
US5449382A (en) * 1992-11-04 1995-09-12 Dayton; Michael P. Minimally invasive bioactivated endoprosthesis for vessel repair
US5484436A (en) * 1991-06-07 1996-01-16 Hemostatic Surgery Corporation Bi-polar electrosurgical instruments and methods of making
US5494881A (en) * 1993-07-29 1996-02-27 Ngk Insulators, Ltd. Ceramic honeycomb structural body and catalyst comprising the same
US5501654A (en) * 1993-07-15 1996-03-26 Ethicon, Inc. Endoscopic instrument having articulating element
US5526822A (en) * 1994-03-24 1996-06-18 Biopsys Medical, Inc. Method and apparatus for automated biopsy and collection of soft tissue
US5527331A (en) * 1993-10-13 1996-06-18 Femrx Method for prostatic tissue resection
US5542948A (en) * 1994-05-24 1996-08-06 Arrow Precision Products, Inc. Surgical combination inject and snare apparatus
US5562102A (en) * 1994-11-21 1996-10-08 Taylor; Thomas V. Multiple biopsy device
US5611803A (en) * 1994-12-22 1997-03-18 Urohealth Systems, Inc. Tissue segmentation device
US5643282A (en) * 1994-08-22 1997-07-01 Kieturakis; Maciej J. Surgical instrument and method for removing tissue from an endoscopic workspace
US5649547A (en) * 1994-03-24 1997-07-22 Biopsys Medical, Inc. Methods and devices for automated biopsy and collection of soft tissue
US5653718A (en) * 1994-05-16 1997-08-05 Yoon; Inbae Cannula anchoring system
US5665085A (en) * 1991-11-01 1997-09-09 Medical Scientific, Inc. Electrosurgical cutting tool
US5674184A (en) * 1994-03-15 1997-10-07 Ethicon Endo-Surgery, Inc. Surgical trocars with cutting electrode and viewing rod
US5735847A (en) * 1995-08-15 1998-04-07 Zomed International, Inc. Multiple antenna ablation apparatus and method with cooling element
US5749887A (en) * 1994-07-13 1998-05-12 C. R. Bard, Inc. Twisted strand localization wire
US5752972A (en) * 1995-11-09 1998-05-19 Hoogeboom; Thomas J. Modular endoscopic surgical instrument
US5755697A (en) * 1995-11-22 1998-05-26 Jones; Calvin E. Self-tunneling, self-securing percutaneous catheterization device and method of use thereof
US5766163A (en) * 1996-07-03 1998-06-16 Eclipse Surgical Technologies, Inc. Controllable trocar for transmyocardial revascularization (TMR) via endocardium method and apparatus
US5769086A (en) * 1995-12-06 1998-06-23 Biopsys Medical, Inc. Control system and method for automated biopsy device
US5794626A (en) * 1994-08-18 1998-08-18 Kieturakis; Maciej J. Excisional stereotactic apparatus
US5795308A (en) * 1995-03-09 1998-08-18 Russin; Lincoln D. Apparatus for coaxial breast biopsy
US5800445A (en) * 1995-10-20 1998-09-01 United States Surgical Corporation Tissue tagging device
US5810764A (en) * 1992-01-07 1998-09-22 Arthrocare Corporation Resecting loop electrode and method for electrosurgical cutting and ablation
US5810806A (en) * 1996-08-29 1998-09-22 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
US5868740A (en) * 1995-03-24 1999-02-09 Board Of Regents-Univ Of Nebraska Method for volumetric tissue ablation
US5879357A (en) * 1995-10-20 1999-03-09 United States Surgical Corporation Apparatus for marking tissue location
US5947964A (en) * 1995-03-03 1999-09-07 Neothermia Corporation Methods and apparatus for therapeutic cauterization of predetermined volumes of biological tissue
US5954670A (en) * 1994-10-05 1999-09-21 Baker; Gary H. Mandrel-guided tandem multiple channel biopsy guide device and method of use
US6022362A (en) * 1998-09-03 2000-02-08 Rubicor Medical, Inc. Excisional biopsy devices and methods
US6059734A (en) * 1995-01-06 2000-05-09 Yoon; Inbae Methods of collecting tissue at obstructed anatomical sites
US6117153A (en) * 1996-10-03 2000-09-12 Interventional Technologies, Inc. Neovascularization catheter
US6133359A (en) * 1992-01-07 2000-10-17 Whitford Plastics Limited Non-stick coatings
US6280450B1 (en) * 1997-07-24 2001-08-28 Rex Medical, Lp Breast surgery method and apparatus
US6363940B1 (en) * 1998-05-14 2002-04-02 Calypso Medical Technologies, Inc. System and method for bracketing and removing tissue
US20020068879A1 (en) * 1998-04-08 2002-06-06 Paul Lubock Dilation devices and methods for removing tissue specimens
US20020077628A1 (en) * 1998-09-01 2002-06-20 Senorx, Inc. Electrosurgical lesion location device
US6454727B1 (en) * 1998-03-03 2002-09-24 Senorx, Inc. Tissue acquisition system and method of use
US6540695B1 (en) * 1998-04-08 2003-04-01 Senorx, Inc. Biopsy anchor device with cutter
US6679851B2 (en) * 1998-09-01 2004-01-20 Senorx, Inc. Tissue accessing and anchoring device and method
US6716179B2 (en) * 1998-03-03 2004-04-06 Senorx, Inc. Sentinel node location and biopsy

Family Cites Families (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US33925A (en) * 1861-12-17 Improvement in fastenings for shoulder-straps
US34056A (en) * 1862-01-07 Edwin gomez
US2447169A (en) 1945-01-16 1948-08-17 Sousa Eugenio De Surgical instrument and technique
DE1225813B (en) 1961-10-23 1966-09-29 Optique Et Prec De Levallois S Saugbiopsiesonde
US3945375A (en) 1972-04-04 1976-03-23 Surgical Design Corporation Rotatable surgical instrument
US3844272A (en) 1969-02-14 1974-10-29 A Banko Surgical instruments
US3598108A (en) 1969-02-28 1971-08-10 Khosrow Jamshidi Biopsy technique and biopsy device
JPS5727445Y2 (en) 1973-06-20 1982-06-15
US3847153A (en) 1973-09-14 1974-11-12 B Weissman Disposable probe tip for electro-surgical device
US4243048A (en) 1976-09-21 1981-01-06 Jim Zegeer Biopsy device
GB2053691B (en) 1979-07-24 1983-04-27 Wolf Gmbh Richard Endoscopes
US4532924A (en) 1980-05-13 1985-08-06 American Hospital Supply Corporation Multipolar electrosurgical device and method
US4565200A (en) 1980-09-24 1986-01-21 Cosman Eric R Universal lesion and recording electrode system
US4493320A (en) 1982-04-02 1985-01-15 Treat Michael R Bipolar electrocautery surgical snare
DE3419962A1 (en) 1983-05-30 1984-12-06 Olympus Optical Co RF incisional and exzisionsinstrument
US4773413A (en) 1983-06-13 1988-09-27 Trimedyne Laser Systems, Inc. Localized heat applying medical device
JPH0414018B2 (en) 1983-11-10 1992-03-11 Tokyo Shibaura Electric Co
EP0146699A1 (en) 1983-12-22 1985-07-03 Gebrüder Sulzer Aktiengesellschaft Implanted marker
US4611594A (en) 1984-04-11 1986-09-16 Northwestern University Medical instrument for containment and removal of calculi
US5066295A (en) 1986-05-13 1991-11-19 Mill-Rose Laboratories, Inc. Rotatable surgical snare
DE3804849A1 (en) 1987-02-19 1988-09-01 Cramer Bernhard M Priv Doz Dr Device for removing blood clots from vessels
DE3721663C3 (en) * 1987-06-26 1997-10-09 Lignotock Gmbh A method for hot pressing of molded articles
US5372138A (en) 1988-03-21 1994-12-13 Boston Scientific Corporation Acousting imaging catheters and the like
DE3916161C2 (en) 1989-05-18 1991-06-13 Richard Wolf Gmbh, 7134 Knittlingen, De
US5041124A (en) 1989-07-14 1991-08-20 Kensey Nash Corporation Apparatus and method for sclerosing of body tissue
US4997435A (en) 1989-09-25 1991-03-05 Methodist Hospital Of Indiana Inc. Percutaneous catheter with encapsulating receptacle
US5797907A (en) 1989-11-06 1998-08-25 Mectra Labs, Inc. Electrocautery cutter
EP0448857A1 (en) 1990-03-27 1991-10-02 Jong-Khing Huang An apparatus of a spinning type of resectoscope for prostatectomy
US5195958A (en) 1990-05-25 1993-03-23 Phillips Edward H Tool for laparoscopic surgery
US5527298A (en) 1990-06-11 1996-06-18 Schneider (Usa) Inc. Tracking guidewire
US5037379A (en) 1990-06-22 1991-08-06 Vance Products Incorporated Surgical tissue bag and method for percutaneously debulking tissue
US5234288A (en) * 1990-06-29 1993-08-10 State Paving Corporation Integrated column and pile
US5163938A (en) 1990-07-19 1992-11-17 Olympus Optical Co., Ltd. High-frequency surgical treating device for use with endoscope
WO1992001425A1 (en) * 1990-07-26 1992-02-06 Rodney James Lane Self expanding vascular endoprosthesis for aneurysms
US5100423A (en) 1990-08-21 1992-03-31 Medical Engineering & Development Institute, Inc. Ablation catheter
US5282799A (en) 1990-08-24 1994-02-01 Everest Medical Corporation Bipolar electrosurgical scalpel with paired loop electrodes
US5133359A (en) 1990-11-14 1992-07-28 Du-Kedem Technologies Ltd. Hard tissue biopsy instrument with rotary drive
US5192270A (en) 1990-11-19 1993-03-09 Carswell Jr Donald D Hypodermic syringe and a method for marking injections
US5085659A (en) 1990-11-21 1992-02-04 Everest Medical Corporation Biopsy device with bipolar coagulation capability
US5984919A (en) 1991-02-13 1999-11-16 Applied Medical Resources Corporation Surgical trocar
US5599347A (en) 1991-02-13 1997-02-04 Applied Medical Resources Corporation Surgical trocar with cutoff circuit
US5133360A (en) 1991-03-07 1992-07-28 Spears Colin P Spears retriever
US5147307A (en) 1991-06-17 1992-09-15 Gluck Seymour M Anatomical marker device and method
US5902272A (en) 1992-01-07 1999-05-11 Arthrocare Corporation Planar ablation probe and method for electrosurgical cutting and ablation
DE69210181D1 (en) * 1991-10-18 1996-05-30 Ethicon Inc Applicator for anti-adhesion layer
US5217468A (en) 1991-10-24 1993-06-08 Mectra Labs, Inc. Tissue encapsulating sheath
DE4235527C2 (en) 1991-10-25 1998-07-09 Morita Mfg Means for detecting a medical X-ray images with automatic exposure
US5308327A (en) 1991-11-25 1994-05-03 Advanced Surgical Inc. Self-deployed inflatable retractor
US5215521A (en) 1991-11-26 1993-06-01 Cochran James C Laparoscopy organ retrieval apparatus and procedure
WO1993013718A1 (en) 1992-01-21 1993-07-22 Valleylab, Inc. Electrosurgical control for a trocar
US5509900A (en) * 1992-03-02 1996-04-23 Kirkman; Thomas R. Apparatus and method for retaining a catheter in a blood vessel in a fixed position
US5201732A (en) 1992-04-09 1993-04-13 Everest Medical Corporation Bipolar sphincterotomy utilizing side-by-side parallel wires
US5217458A (en) * 1992-04-09 1993-06-08 Everest Medical Corporation Bipolar biopsy device utilizing a rotatable, single-hinged moving element
US5562720A (en) * 1992-05-01 1996-10-08 Vesta Medical, Inc. Bipolar/monopolar endometrial ablation device and method
US5281218A (en) 1992-06-05 1994-01-25 Cardiac Pathways Corporation Catheter having needle electrode for radiofrequency ablation
US5311858A (en) 1992-06-15 1994-05-17 Adair Edwin Lloyd Imaging tissue or stone removal basket
US5221281A (en) 1992-06-30 1993-06-22 Valleylab Inc. Electrosurgical tubular trocar
WO1994001536A1 (en) 1992-07-07 1994-01-20 University Research Corporation Cancer immunotherapy with antibodies to cancer procoagulant
DK91092D0 (en) 1992-07-10 1992-07-10 Novo Nordisk As
WO1994002077A3 (en) 1992-07-15 1994-04-14 Angelase Inc Ablation catheter system
US5370675A (en) 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
US5470308A (en) 1992-08-12 1995-11-28 Vidamed, Inc. Medical probe with biopsy stylet
US5409453A (en) 1992-08-12 1995-04-25 Vidamed, Inc. Steerable medical probe with stylets
US5542916A (en) 1992-08-12 1996-08-06 Vidamed, Inc. Dual-channel RF power delivery system
US5741225A (en) 1992-08-12 1998-04-21 Rita Medical Systems Method for treating the prostate
US5295990A (en) 1992-09-11 1994-03-22 Levin John M Tissue sampling and removal device
US5549108A (en) 1992-09-25 1996-08-27 Ep Technologies, Inc. Cardiac mapping and ablation systems
US5441498A (en) 1994-02-16 1995-08-15 Envision Surgical Systems, Inc. Method of using a multimodality probe with extendable bipolar electrodes
US5401272A (en) 1992-09-25 1995-03-28 Envision Surgical Systems, Inc. Multimodality probe with extendable bipolar electrodes
US5471982A (en) * 1992-09-29 1995-12-05 Ep Technologies, Inc. Cardiac mapping and ablation systems
CA2102084A1 (en) 1992-11-09 1994-05-10 Howard C. Topel Surgical cutting instrument for coring tissue affixed thereto
US5501694A (en) 1992-11-13 1996-03-26 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5330483A (en) 1992-12-18 1994-07-19 Advanced Surgical Inc. Specimen reduction device
US5425705A (en) * 1993-02-22 1995-06-20 Stanford Surgical Technologies, Inc. Thoracoscopic devices and methods for arresting the heart
US5578031A (en) 1993-05-10 1996-11-26 Wilk; Peter J. Laparoscopic instrument assembly and associated method
WO1994027670A1 (en) 1993-06-02 1994-12-08 Cardiac Pathways Corporation Catheter having tip with fixation means
DE69432148D1 (en) 1993-07-01 2003-03-27 Boston Scient Ltd Catheter for image display, for displaying electrical signals and for ablation
GB9314640D0 (en) 1993-07-15 1993-08-25 Salim Aws S M Tunnellimg catheter
GB9314641D0 (en) 1993-07-15 1993-08-25 Salim Aws S M Tunnelling umbrella
US5374188A (en) 1993-07-19 1994-12-20 Bei Medical Systems, Inc. Electro-surgical instrument and method for use with dental implantations
WO1995003843A1 (en) 1993-07-30 1995-02-09 The Regents Of The University Of California Endocardial infusion catheter
US5376094A (en) 1993-08-19 1994-12-27 Boston Scientific Corporation Improved actuating handle with pulley system for providing mechanical advantage to a surgical working element
US5431649A (en) 1993-08-27 1995-07-11 Medtronic, Inc. Method and apparatus for R-F ablation
US5840044A (en) 1993-09-30 1998-11-24 Boston Scientific Corporation Multiple biopsy sampling forceps
US5573008A (en) 1993-10-29 1996-11-12 Boston Scientific Corporation Multiple biopsy sampling coring device
US5683384A (en) 1993-11-08 1997-11-04 Zomed Multiple antenna ablation apparatus
US5728143A (en) 1995-08-15 1998-03-17 Rita Medical Systems, Inc. Multiple antenna ablation apparatus and method
US5507743A (en) 1993-11-08 1996-04-16 Zomed International Coiled RF electrode treatment apparatus
US6090105A (en) 1995-08-15 2000-07-18 Rita Medical Systems, Inc. Multiple electrode ablation apparatus and method
US5487385A (en) 1993-12-03 1996-01-30 Avitall; Boaz Atrial mapping and ablation catheter system
US5554159A (en) 1994-02-04 1996-09-10 Fischer; Nathan R. Instrument for electro-surgical excisor for the transformation zone of the uterine cervix and method of using same
US5403310A (en) 1994-02-04 1995-04-04 Fischer; Nathan R. Instrument for electro-surgical excisor for the transformation zone of the uterine cervix and method of using same
US5397320A (en) 1994-03-03 1995-03-14 Essig; Mitchell N. Dissecting surgical device and associated method
US5477862A (en) 1994-03-14 1995-12-26 Haaga; John R. Cutting tip for biopsy needle
US5595185A (en) 1994-08-11 1997-01-21 N.M.B. Medical Applications Ltd. Single puncture multi-biopsy gun
US5509916A (en) 1994-08-12 1996-04-23 Valleylab Inc. Laser-assisted electrosurgery system
US5697946A (en) 1994-10-07 1997-12-16 Origin Medsystems, Inc. Method and apparatus for anchoring laparoscopic instruments
US6032673A (en) 1994-10-13 2000-03-07 Femrx, Inc. Methods and devices for tissue removal
US5578030A (en) 1994-11-04 1996-11-26 Levin; John M. Biopsy needle with cauterization feature
US5684739A (en) 1994-11-30 1997-11-04 Nkk Corporation Apparatus and method for determining current or voltage of a semiconductor device
US5603711A (en) 1995-01-20 1997-02-18 Everest Medical Corp. Endoscopic bipolar biopsy forceps
US5814044A (en) 1995-02-10 1998-09-29 Enable Medical Corporation Apparatus and method for morselating and removing tissue from a patient
CA2168694A1 (en) 1995-03-20 1996-09-21 Wayne P. Young Trocar assembly with electrocautery penetrating tip
DE19515280C2 (en) 1995-04-26 1997-06-12 Siegfried Riek Device like from the peritoneal cavity to remove tissue or
US5700273A (en) 1995-07-14 1997-12-23 C.R. Bard, Inc. Wound closure apparatus and method
DE19528440C2 (en) 1995-08-02 1998-09-10 Harald Dr Med Kuebler A surgical cutting instrument
US5817034A (en) 1995-09-08 1998-10-06 United States Surgical Corporation Apparatus and method for removing tissue
US5857982A (en) 1995-09-08 1999-01-12 United States Surgical Corporation Apparatus and method for removing tissue
US5782775A (en) 1995-10-20 1998-07-21 United States Surgical Corporation Apparatus and method for localizing and removing tissue
US5857981A (en) 1995-09-12 1999-01-12 Bucalo; Brian D. Biopsy instrument with tissue specimen retaining and retrieval device
US5853374A (en) 1995-10-11 1998-12-29 Applied Medical Resources Corporation Tissue collection and retrieval bag
US5848978A (en) * 1995-11-14 1998-12-15 Genx International, Inc. Surgical biopsy device
US5676663A (en) 1995-11-21 1997-10-14 Kim; David S. Cone biopsy instrument
US5687739A (en) 1995-12-06 1997-11-18 Interventional Concepts, Inc. Biopsy specimen cutter
US6126656A (en) 1996-01-30 2000-10-03 Utah Medical Products, Inc. Electrosurgical cutting device
US5730726A (en) 1996-03-04 1998-03-24 Klingenstein; Ralph James Apparatus and method for removing fecal impaction
US6139527A (en) 1996-03-05 2000-10-31 Vnus Medical Technologies, Inc. Method and apparatus for treating hemorrhoids
DE69725005D1 (en) 1996-03-25 2003-10-23 Safe Conduct Ab Varberg A device for removal of tissue or the like
DE19706751A1 (en) 1996-03-27 1997-10-02 Valleylab Inc An electrosurgical instrument for ablating tissue in body spaces
US5725521A (en) 1996-03-29 1998-03-10 Eclipse Surgical Technologies, Inc. Depth stop apparatus and method for laser-assisted transmyocardial revascularization and other surgical applications
US5733283A (en) 1996-06-05 1998-03-31 Malis; Jerry L. Flat loop bipolar electrode tips for electrosurgical instrument
DE19626408A1 (en) 1996-07-01 1998-01-08 Berchtold Gmbh & Co Geb Trocar for laparoscopic surgery
WO1998004441A1 (en) 1996-07-26 1998-02-05 Cascade Engineering, Inc. System for fastening sheet materials together
US5902310A (en) 1996-08-12 1999-05-11 Ethicon Endo-Surgery, Inc. Apparatus and method for marking tissue
US5882316A (en) 1996-08-29 1999-03-16 City Of Hope Minimally invasive biopsy device
US5913857A (en) 1996-08-29 1999-06-22 Ethicon End0-Surgery, Inc. Methods and devices for collection of soft tissue
US5769794A (en) 1996-09-04 1998-06-23 Smith & Nephew Endoscopy, Inc Tissue retrieval bag and method for removing cancerous tissue
US5827268A (en) 1996-10-30 1998-10-27 Hearten Medical, Inc. Device for the treatment of patent ductus arteriosus and method of using the device
CA2273149A1 (en) * 1996-12-02 1998-06-11 Angiotrax, Inc. Apparatus and methods for percutaneously performing surgery
US6254628B1 (en) * 1996-12-09 2001-07-03 Micro Therapeutics, Inc. Intracranial stent
US5882329A (en) 1997-02-12 1999-03-16 Prolifix Medical, Inc. Apparatus and method for removing stenotic material from stents
CA2201458C (en) 1997-04-01 2001-06-12 George A. Vilos Improved resectoscope
US5759202A (en) * 1997-04-28 1998-06-02 Sulzer Intermedics Inc. Endocardial lead with lateral active fixation
US5984920A (en) 1997-05-09 1999-11-16 Medi-Globe Corporation Rotatable sphincterotome/papillotome and method of use
US6050992A (en) 1997-05-19 2000-04-18 Radiotherapeutics Corporation Apparatus and method for treating tissue with multiple electrodes
US6383145B1 (en) 1997-09-12 2002-05-07 Imagyn Medical Technologies California, Inc. Incisional breast biopsy device
US6142955A (en) 1997-09-19 2000-11-07 United States Surgical Corporation Biopsy apparatus and method
US6050955A (en) 1997-09-19 2000-04-18 United States Surgical Corporation Biopsy apparatus and method
US6494881B1 (en) 1997-09-30 2002-12-17 Scimed Life Systems, Inc. Apparatus and method for electrode-surgical tissue removal having a selectively insulated electrode
US6063082A (en) 1997-11-04 2000-05-16 Scimed Life Systems, Inc. Percutaneous myocardial revascularization basket delivery system and radiofrequency therapeutic device
US6484050B1 (en) 1997-11-18 2002-11-19 Care Wise Medical Products Corporation Minimally invasive surgical instrument for tissue identification, dislodgment and retrieval and methods of use
US6106542A (en) 1998-01-23 2000-08-22 Microsurgical Laboratories, Inc. Surgical forceps
US6659105B2 (en) 1998-02-26 2003-12-09 Senorx, Inc. Tissue specimen isolating and damaging device and method
US6758848B2 (en) 1998-03-03 2004-07-06 Senorx, Inc. Apparatus and method for accessing a body site
US6497706B1 (en) 1998-03-03 2002-12-24 Senorx, Inc. Biopsy device and method of use
US6540693B2 (en) * 1998-03-03 2003-04-01 Senorx, Inc. Methods and apparatus for securing medical instruments to desired locations in a patients body
US6471700B1 (en) 1998-04-08 2002-10-29 Senorx, Inc. Apparatus and method for accessing biopsy site
US6331166B1 (en) 1998-03-03 2001-12-18 Senorx, Inc. Breast biopsy system and method
US6344026B1 (en) 1998-04-08 2002-02-05 Senorx, Inc. Tissue specimen encapsulation device and method thereof
US6261241B1 (en) 1998-03-03 2001-07-17 Senorx, Inc. Electrosurgical biopsy device and method
US5951550A (en) 1998-03-11 1999-09-14 Utah Medical Products, Inc. Endocervical conization electrode apparatus
US6007497A (en) 1998-06-30 1999-12-28 Ethicon Endo-Surgery, Inc. Surgical biopsy device
US6120462A (en) 1999-03-31 2000-09-19 Ethicon Endo-Surgery, Inc. Control method for an automated surgical biopsy device
US6514248B1 (en) 1999-10-15 2003-02-04 Neothermia Corporation Accurate cutting about and into tissue volumes with electrosurgically deployed electrodes
US20020072739A1 (en) 2000-12-07 2002-06-13 Roberta Lee Methods and devices for radiofrequency electrosurgery
US6520421B2 (en) * 2000-12-29 2003-02-18 Siemens Automotive Corporation Modular fuel injector having an integral filter and o-ring retainer
US6671637B2 (en) 2002-01-29 2003-12-30 Sumitomo Heavy Industries, Ltd. Thrust ripple measuring apparatus and method in linear motor

Patent Citations (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2032860A (en) * 1933-03-24 1936-03-03 Wappler Frederick Charles Method for electrosurgical treatment of tissue
US3805791A (en) * 1971-07-01 1974-04-23 K Seuberth Apparatus for the diathermic removal of growths
US3955578A (en) * 1974-12-23 1976-05-11 Cook Inc. Rotatable surgical snare
US4007732A (en) * 1975-09-02 1977-02-15 Robert Carl Kvavle Method for location and removal of soft tissue in human biopsy operations
US4202338A (en) * 1977-11-18 1980-05-13 Richard Wolf Gmbh Device for removing excrescences and polyps
US4294254A (en) * 1977-12-08 1981-10-13 Chamness Dale L Surgical apparatus
US4311143A (en) * 1978-10-12 1982-01-19 Olympus Optical Co., Ltd. Apparatus for resecting tissue inside the body cavity utilizing high-frequency currents
US4425908A (en) * 1981-10-22 1984-01-17 Beth Israel Hospital Blood clot filter
US4503855A (en) * 1981-12-31 1985-03-12 Harald Maslanka High frequency surgical snare electrode
US4576162A (en) * 1983-03-30 1986-03-18 Mccorkle Charles E Apparatus and method for separation of scar tissue in venous pathway
USRE33925E (en) * 1984-05-22 1992-05-12 Cordis Corporation Electrosurgical catheter aned method for vascular applications
US4638802A (en) * 1984-09-21 1987-01-27 Olympus Optical Co., Ltd. High frequency instrument for incision and excision
US4592356A (en) * 1984-09-28 1986-06-03 Pedro Gutierrez Localizing device
US4724836A (en) * 1985-01-08 1988-02-16 Olympus Optical Co., Ltd. High-frequency incision tool
US4616656A (en) * 1985-03-19 1986-10-14 Nicholson James E Self-actuating breast lesion probe and method of using
US4718419A (en) * 1985-08-05 1988-01-12 Olympus Optical Co., Ltd. Snare assembly for endoscope
US4682606A (en) * 1986-02-03 1987-07-28 Decaprio Vincent H Localizing biopsy apparatus
US4774948A (en) * 1986-11-24 1988-10-04 Markham Charles W Marking and retraction needle having retrievable stylet
US5441503A (en) * 1988-09-24 1995-08-15 Considine; John Apparatus for removing tumors from hollow organs of the body
US4966583A (en) * 1989-02-03 1990-10-30 Elie Debbas Apparatus for locating a breast mass
US5024617A (en) * 1989-03-03 1991-06-18 Wilson-Cook Medical, Inc. Sphincterotomy method and device having controlled bending and orientation
US5059197A (en) * 1989-04-15 1991-10-22 Urie Robert G Lesion location device
US5234426A (en) * 1989-06-15 1993-08-10 Research Corporation Technologies, Inc. Helical-tipped lesion localization needle device and method of using the same
USRE34056E (en) * 1989-07-31 1992-09-08 C.R. Bard, Inc. Tissue sampling device
US5007908A (en) * 1989-09-29 1991-04-16 Everest Medical Corporation Electrosurgical instrument having needle cutting electrode and spot-coag electrode
US5335671A (en) * 1989-11-06 1994-08-09 Mectra Labs, Inc. Tissue removal assembly with provision for an electro-cautery device
US5158084A (en) * 1989-11-22 1992-10-27 Board Of Regents, The University Of Texas System Modified localization wire for excisional biopsy
US5035696A (en) * 1990-02-02 1991-07-30 Everest Medical Corporation Electrosurgical instrument for conducting endoscopic retrograde sphincterotomy
US5047027A (en) * 1990-04-20 1991-09-10 Everest Medical Corporation Tumor resector
US5078716A (en) * 1990-05-11 1992-01-07 Doll Larry F Electrosurgical apparatus for resecting abnormal protruding growth
US5080660A (en) * 1990-05-11 1992-01-14 Applied Urology, Inc. Electrosurgical electrode
US5201741A (en) * 1990-07-24 1993-04-13 Andrew Surgical, Inc. Surgical snare with shape memory effect wire
US5353804A (en) * 1990-09-18 1994-10-11 Peb Biopsy Corporation Method and device for percutaneous exisional breast biopsy
US5111828A (en) * 1990-09-18 1992-05-12 Peb Biopsy Corporation Device for percutaneous excisional breast biopsy
US5221269A (en) * 1990-10-15 1993-06-22 Cook Incorporated Guide for localizing a nonpalpable breast lesion
US5210732A (en) * 1990-11-27 1993-05-11 Matsushita Electric Industrial Co., Ltd. Optical disk apparatus
US5344420A (en) * 1991-02-13 1994-09-06 Applied Medical Resources Corporation Surgical trocar
US5323768A (en) * 1991-04-22 1994-06-28 Olympus Optical Co., Ltd. Diathermic dissector with a bifurcation having substantially the same cross-sectional area as a lumen for guiding a wire
US5324288A (en) * 1991-04-30 1994-06-28 Utah Medical Products, Inc. Electrosurgical loop with a depth gauge
US5484436A (en) * 1991-06-07 1996-01-16 Hemostatic Surgery Corporation Bi-polar electrosurgical instruments and methods of making
US5196007A (en) * 1991-06-07 1993-03-23 Alan Ellman Electrosurgical handpiece with activator
US5395312A (en) * 1991-10-18 1995-03-07 Desai; Ashvin Surgical tool
US5665085A (en) * 1991-11-01 1997-09-09 Medical Scientific, Inc. Electrosurgical cutting tool
US5423770A (en) * 1991-12-06 1995-06-13 Yoon; Inbae Automatic retractable safety penetrating instrument
US5810764A (en) * 1992-01-07 1998-09-22 Arthrocare Corporation Resecting loop electrode and method for electrosurgical cutting and ablation
US6133359A (en) * 1992-01-07 2000-10-17 Whitford Plastics Limited Non-stick coatings
US5158561A (en) * 1992-03-23 1992-10-27 Everest Medical Corporation Monopolar polypectomy snare with coagulation electrode
US5207686A (en) * 1992-04-15 1993-05-04 Stuart Dolgin Surgical snare
US5462553A (en) * 1992-04-15 1995-10-31 Dolgin; Stuart Surgical snare with a frangible loop
US5318564A (en) * 1992-05-01 1994-06-07 Hemostatic Surgery Corporation Bipolar surgical snare and methods of use
US5423814A (en) * 1992-05-08 1995-06-13 Loma Linda University Medical Center Endoscopic bipolar coagulation device
US5224488A (en) * 1992-08-31 1993-07-06 Neuffer Francis H Biopsy needle with extendable cutting means
US5312400A (en) * 1992-10-09 1994-05-17 Symbiosis Corporation Cautery probes for endoscopic electrosurgical suction-irrigation instrument
US5449382A (en) * 1992-11-04 1995-09-12 Dayton; Michael P. Minimally invasive bioactivated endoprosthesis for vessel repair
US5380321A (en) * 1992-11-04 1995-01-10 Yoon; Inbae Shielded energy transmitting surgical instrument and methods therefor
US5417687A (en) * 1993-04-30 1995-05-23 Medical Scientific, Inc. Bipolar electrosurgical trocar
US5409004A (en) * 1993-06-11 1995-04-25 Cook Incorporated Localization device with radiopaque markings
US5417697A (en) * 1993-07-07 1995-05-23 Wilk; Peter J. Polyp retrieval assembly with cauterization loop and suction web
US5501654A (en) * 1993-07-15 1996-03-26 Ethicon, Inc. Endoscopic instrument having articulating element
US5494881A (en) * 1993-07-29 1996-02-27 Ngk Insulators, Ltd. Ceramic honeycomb structural body and catalyst comprising the same
US5395313A (en) * 1993-08-13 1995-03-07 Naves; Neil H. Reciprocating arthroscopic shaver
US5415656A (en) * 1993-09-28 1995-05-16 American Medical Systems, Inc. Electrosurgical apparatus
US5437665A (en) * 1993-10-12 1995-08-01 Munro; Malcolm G. Electrosurgical loop electrode instrument for laparoscopic surgery
US5527331A (en) * 1993-10-13 1996-06-18 Femrx Method for prostatic tissue resection
US5674184A (en) * 1994-03-15 1997-10-07 Ethicon Endo-Surgery, Inc. Surgical trocars with cutting electrode and viewing rod
US5649547A (en) * 1994-03-24 1997-07-22 Biopsys Medical, Inc. Methods and devices for automated biopsy and collection of soft tissue
US5526822A (en) * 1994-03-24 1996-06-18 Biopsys Medical, Inc. Method and apparatus for automated biopsy and collection of soft tissue
US5653718A (en) * 1994-05-16 1997-08-05 Yoon; Inbae Cannula anchoring system
US5542948A (en) * 1994-05-24 1996-08-06 Arrow Precision Products, Inc. Surgical combination inject and snare apparatus
US5749887A (en) * 1994-07-13 1998-05-12 C. R. Bard, Inc. Twisted strand localization wire
US5794626A (en) * 1994-08-18 1998-08-18 Kieturakis; Maciej J. Excisional stereotactic apparatus
US5643282A (en) * 1994-08-22 1997-07-01 Kieturakis; Maciej J. Surgical instrument and method for removing tissue from an endoscopic workspace
US5954670A (en) * 1994-10-05 1999-09-21 Baker; Gary H. Mandrel-guided tandem multiple channel biopsy guide device and method of use
US5562102A (en) * 1994-11-21 1996-10-08 Taylor; Thomas V. Multiple biopsy device
US5611803A (en) * 1994-12-22 1997-03-18 Urohealth Systems, Inc. Tissue segmentation device
US6059734A (en) * 1995-01-06 2000-05-09 Yoon; Inbae Methods of collecting tissue at obstructed anatomical sites
US5947964A (en) * 1995-03-03 1999-09-07 Neothermia Corporation Methods and apparatus for therapeutic cauterization of predetermined volumes of biological tissue
US5795308A (en) * 1995-03-09 1998-08-18 Russin; Lincoln D. Apparatus for coaxial breast biopsy
US5868740A (en) * 1995-03-24 1999-02-09 Board Of Regents-Univ Of Nebraska Method for volumetric tissue ablation
US5735847A (en) * 1995-08-15 1998-04-07 Zomed International, Inc. Multiple antenna ablation apparatus and method with cooling element
US5800445A (en) * 1995-10-20 1998-09-01 United States Surgical Corporation Tissue tagging device
US5879357A (en) * 1995-10-20 1999-03-09 United States Surgical Corporation Apparatus for marking tissue location
US5752972A (en) * 1995-11-09 1998-05-19 Hoogeboom; Thomas J. Modular endoscopic surgical instrument
US5755697A (en) * 1995-11-22 1998-05-26 Jones; Calvin E. Self-tunneling, self-securing percutaneous catheterization device and method of use thereof
US5769086A (en) * 1995-12-06 1998-06-23 Biopsys Medical, Inc. Control system and method for automated biopsy device
US5766163A (en) * 1996-07-03 1998-06-16 Eclipse Surgical Technologies, Inc. Controllable trocar for transmyocardial revascularization (TMR) via endocardium method and apparatus
US5810806A (en) * 1996-08-29 1998-09-22 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
US6117153A (en) * 1996-10-03 2000-09-12 Interventional Technologies, Inc. Neovascularization catheter
US6280450B1 (en) * 1997-07-24 2001-08-28 Rex Medical, Lp Breast surgery method and apparatus
US6716179B2 (en) * 1998-03-03 2004-04-06 Senorx, Inc. Sentinel node location and biopsy
US6454727B1 (en) * 1998-03-03 2002-09-24 Senorx, Inc. Tissue acquisition system and method of use
US6712775B2 (en) * 1998-03-03 2004-03-30 Senorx, Inc. Tissue acquisition system and method of use
US20020068879A1 (en) * 1998-04-08 2002-06-06 Paul Lubock Dilation devices and methods for removing tissue specimens
US20030144605A1 (en) * 1998-04-08 2003-07-31 Senorx, Inc. Biopsy anchor device with cutter
US6540695B1 (en) * 1998-04-08 2003-04-01 Senorx, Inc. Biopsy anchor device with cutter
US6363940B1 (en) * 1998-05-14 2002-04-02 Calypso Medical Technologies, Inc. System and method for bracketing and removing tissue
US6679851B2 (en) * 1998-09-01 2004-01-20 Senorx, Inc. Tissue accessing and anchoring device and method
US20020077628A1 (en) * 1998-09-01 2002-06-20 Senorx, Inc. Electrosurgical lesion location device
US6022362A (en) * 1998-09-03 2000-02-08 Rubicor Medical, Inc. Excisional biopsy devices and methods

Cited By (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9216012B2 (en) 1998-09-01 2015-12-22 Senorx, Inc Methods and apparatus for securing medical instruments to desired locations in a patient's body
US9510809B2 (en) 1999-01-27 2016-12-06 Senorx, Inc. Tissue specimen isolating and damaging device and method
US8821835B2 (en) 2000-11-16 2014-09-02 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
US8470294B2 (en) 2000-11-16 2013-06-25 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
US9636401B2 (en) 2000-11-16 2017-05-02 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
US9636402B2 (en) 2000-11-16 2017-05-02 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
US8066627B2 (en) 2001-11-02 2011-11-29 Biocompatibles Uk Limited Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings
US20040102671A1 (en) * 2001-11-02 2004-05-27 Terwilliger Richard A. Delivery system and method for interstitial radiation therapy using seed strands constructed with preformed strand housing
US20100121130A1 (en) * 2001-11-02 2010-05-13 Biocompatibles Uk Limited Delivery system and method for interstitial radiation therapy
US7942803B2 (en) 2001-11-02 2011-05-17 Biocompatibles Uk Limited Delivery system and method for interstitial radiation therapy
US7874974B2 (en) 2001-11-02 2011-01-25 Biocompatibles Uk Limited Delivery system and method for interstitial radiation therapy
US7736295B2 (en) 2003-05-13 2010-06-15 Biocompatibles Uk Limited Delivery system and method for interstitial radiation therapy using custom end spacing
US20060074270A1 (en) * 2003-05-13 2006-04-06 World Wide Medical Technologies, Llc Delivery system and method for interstitial radiation therapy using seed strands with custom end spacing
US7736294B2 (en) 2003-05-13 2010-06-15 Biocompatibles Uk Limited Delivery system and method for interstitial radiation therapy using seed strands with custom end spacing
US20060217635A1 (en) * 2005-03-24 2006-09-28 Mccombs Elizabeth S Biopsy device marker deployment
US20090149692A1 (en) * 2005-07-22 2009-06-11 Biocompatibles Uk Limited Implants for use in brachytherapy and other radiation therapy that resist migration and rotation
US8790235B2 (en) 2005-07-22 2014-07-29 Eckert & Ziegler Debig S.A. Devices to resist migration and rotation of implants used in brachytherapy and other radiation therapy
US20090099402A1 (en) * 2005-07-22 2009-04-16 Biocompatibles Uk Limited Implants for use in brachytherapy and other radiation therapy that resist migration and rotation
US20090124846A1 (en) * 2005-07-22 2009-05-14 Biocompatibles Uk Limited Anchor seed cartridge for use with brachytherapy applicator
US7972261B2 (en) 2005-07-22 2011-07-05 Biocompatibles Uk Limited Devices to resist migration and rotation of implants used in brachytherapy and other radiation therapy
US8795146B2 (en) 2005-07-22 2014-08-05 Eckert & Ziegler Bebig S.A. Implants including spacers for use in brachytherapy and other radiation therapy that resist migration and rotation
US20070021643A1 (en) * 2005-07-22 2007-01-25 World Wide Medical Technologies, Llc Implants for use in brachytherapy and other radiation therapy that resist migration and rotation
US20070021642A1 (en) * 2005-07-22 2007-01-25 Worldwide Medical Technologies Llc Devices to resist migration and rotation of implants used in brachytherapy and other radiation therapy
US8192345B2 (en) 2005-07-22 2012-06-05 Biocompatibles, UK Cartridge for use with brachytherapy applicator
US8021291B2 (en) 2005-07-22 2011-09-20 Biocompatibles Uk Limited Markers for use in brachytherapy and other radiation therapy that resist migration and rotation
US7736293B2 (en) 2005-07-22 2010-06-15 Biocompatibles Uk Limited Implants for use in brachytherapy and other radiation therapy that resist migration and rotation
US8187159B2 (en) 2005-07-22 2012-05-29 Biocompatibles, UK Therapeutic member including a rail used in brachytherapy and other radiation therapy
US8114007B2 (en) 2005-07-22 2012-02-14 Biocompatibles Uk Limited Implants for use in brachytherapy and other radiation therapy that resist migration and rotation
US20070197854A1 (en) * 2006-01-27 2007-08-23 Circulite, Inc. Heart assist system
US8157720B2 (en) 2006-01-27 2012-04-17 Circulite, Inc. Heart assist system
US8361032B2 (en) * 2006-02-22 2013-01-29 Carefusion 2200 Inc. Curable material delivery device with a rotatable supply section
US20070197971A1 (en) * 2006-02-22 2007-08-23 Krueger John A Curable material delivery device with a rotatable supply section
US20070265488A1 (en) * 2006-05-09 2007-11-15 Worldwide Medical Technologies Llc After-loader for positioning implants for needle delivery in brachytherapy and other radiation therapy
US20080009660A1 (en) * 2006-05-09 2008-01-10 Worldwide Medical Technologies Llc After-Loader Devices and Kits
US20080009661A1 (en) * 2006-05-09 2008-01-10 Worldwide Medical Technologies Llc Methods for Using After-Loaders
US7988611B2 (en) 2006-05-09 2011-08-02 Biocompatibles Uk Limited After-loader for positioning implants for needle delivery in brachytherapy and other radiation therapy
US7985172B2 (en) 2006-05-09 2011-07-26 Biocompatibles Uk Limited After-loader devices and kits
US20090318950A1 (en) * 2006-07-24 2009-12-24 Yossi Gross Fibroid treatment apparatus and method
US8357176B2 (en) 2006-07-24 2013-01-22 Fibro Control, Inc. Fibroid treatment apparatus and method
US8333686B2 (en) * 2006-08-30 2012-12-18 Circulite, Inc. Cannula insertion devices, systems, and methods including a compressible member
US9572917B2 (en) 2006-08-30 2017-02-21 Circulite, Inc. Devices, methods and systems for establishing supplemental blood flow in the circulatory system
US20080076960A1 (en) * 2006-08-30 2008-03-27 Circulite, Inc. Cannula insertion devices, systems, and methods including a compressible member
US20080076959A1 (en) * 2006-08-30 2008-03-27 Circulite, Inc. Devices, methods and systems for establishing supplemental blood flow in the circulatory system
US20090182188A1 (en) * 2006-08-30 2009-07-16 Circulite, Inc. Devices, methods and systems for establishing supplemental blood flow in the circulatory system
US7905823B2 (en) 2006-08-30 2011-03-15 Circulite, Inc. Devices, methods and systems for establishing supplemental blood flow in the circulatory system
US7874976B1 (en) 2006-09-07 2011-01-25 Biocompatibles Uk Limited Echogenic strands and spacers therein
US7878964B1 (en) 2006-09-07 2011-02-01 Biocompatibles Uk Limited Echogenic spacers and strands
US20090171137A1 (en) * 2006-09-14 2009-07-02 Circulite, Inc. Intravascular blood pump and catheter
US8545380B2 (en) 2006-09-14 2013-10-01 Circulite, Inc. Intravascular blood pump and catheter
US20080269540A1 (en) * 2007-04-27 2008-10-30 Worldwide Medical Technologies Llc Seed cartridge adaptor and methods for use therewith
US20090023975A1 (en) * 2007-07-19 2009-01-22 Circulite, Inc. Cannula for heart chamber implantation and related systems and methods
US8545379B2 (en) 2007-07-19 2013-10-01 Circulite, Inc. Cannula for heart chamber implantation and related systems and methods
EP2891502A1 (en) * 2007-08-29 2015-07-08 CircuLite, Inc. Cannula insertion devices, systems, and methods including a compressible member
WO2009029387A1 (en) * 2007-08-29 2009-03-05 Circulite, Inc. Cannula insertion devices, systems, and methods including a compressible member
US9730792B2 (en) 2007-09-13 2017-08-15 Georg Lutter Truncated cone heart valve stent
US9254192B2 (en) 2007-09-13 2016-02-09 Georg Lutter Truncated cone heart valve stent
US9078749B2 (en) 2007-09-13 2015-07-14 Georg Lutter Truncated cone heart valve stent
US8147480B2 (en) 2007-09-28 2012-04-03 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US8439892B2 (en) 2007-09-28 2013-05-14 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US20090088695A1 (en) * 2007-09-28 2009-04-02 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US20090088730A1 (en) * 2007-09-28 2009-04-02 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US7766875B2 (en) * 2007-09-28 2010-08-03 Codman & Shurtleff, Inc. Catheter for reduced reflux in targeted tissue delivery of a therapeutic agent
US8343029B2 (en) 2007-10-24 2013-01-01 Circulite, Inc. Transseptal cannula, tip, delivery system, and method
US20090216063A1 (en) * 2008-01-29 2009-08-27 Biocompatibles Uk Limited Bio-absorbable brachytherapy strands
WO2010093837A3 (en) * 2009-02-11 2010-12-16 Tendyne Medical, Inc. Percutaneous mitral annular stitch to decrease mitral regurgitation
WO2010093834A2 (en) * 2009-02-12 2010-08-19 Incube Labs, Llc Skin penetrating device and method for subcutaneous solid drug delivery
US20100204678A1 (en) * 2009-02-12 2010-08-12 Mir Imran Skin penetrating device and method for subcutaneous solid drug delivery
WO2010093834A3 (en) * 2009-02-12 2010-12-09 Incube Labs, Llc Skin penetrating device and method for subcutaneous solid drug delivery
US8353863B2 (en) 2009-02-12 2013-01-15 InCube Labs, Inc. Skin penetrating device and method for subcutaneous solid drug delivery
US20100249490A1 (en) * 2009-03-27 2010-09-30 Circulite, Inc. Transseptal cannula device, coaxial balloon delivery device, and methods of using the same
US20100249491A1 (en) * 2009-03-27 2010-09-30 Circulite, Inc. Two-piece transseptal cannula, delivery system, and method of delivery
US8460168B2 (en) 2009-03-27 2013-06-11 Circulite, Inc. Transseptal cannula device, coaxial balloon delivery device, and methods of using the same
US20110022073A1 (en) * 2009-07-27 2011-01-27 Fibro Control, Inc. Balloon with rigid tube for occluding the uterine artery
US8403953B2 (en) 2009-07-27 2013-03-26 Fibro Control, Inc. Balloon with rigid tube for occluding the uterine artery
US9962526B2 (en) 2009-08-14 2018-05-08 The Regents Of The University Of Michigan Integrated vascular delivery system
US8668674B2 (en) 2009-08-14 2014-03-11 The Regents Of The University Of Michigan Integrated vascular delivery system
WO2011019985A3 (en) * 2009-08-14 2011-06-16 The Regents Of The University Of Michigan Integrated vascular delivery system
CN102573980A (en) * 2009-08-14 2012-07-11 密执安州立大学董事会 Integrated vascular delivery system
US8968252B2 (en) 2009-08-14 2015-03-03 The Regents Of The University Of Michigan Integrated vascular delivery system
US8790310B2 (en) 2009-08-14 2014-07-29 The Regents Of The University Of Michigan Integrated vascular delivery system
US20110040281A1 (en) * 2009-08-14 2011-02-17 White Steven B Integrated vascular delivery system
US8323249B2 (en) 2009-08-14 2012-12-04 The Regents Of The University Of Michigan Integrated vascular delivery system
US9592366B2 (en) 2009-08-14 2017-03-14 The Regents Of The University Of Michigan Integrated vascular delivery system
US20110054487A1 (en) * 2009-09-02 2011-03-03 Circulite, Inc. Coaxial transseptal guide-wire and needle assembly
US20110112353A1 (en) * 2009-11-09 2011-05-12 Circulite, Inc. Bifurcated outflow cannulae
US8308715B2 (en) 2009-11-13 2012-11-13 Circulite, Inc. Cannula stabilizer
US20110118668A1 (en) * 2009-11-13 2011-05-19 Circulite, Inc. Cannula stabilizer
US9750866B2 (en) 2010-02-11 2017-09-05 Circulite, Inc. Cannula lined with tissue in-growth material
US9132216B2 (en) 2010-02-11 2015-09-15 Circulite, Inc. Devices, methods and systems for establishing supplemental blood flow in the circulatory system
US20110196190A1 (en) * 2010-02-11 2011-08-11 Circulite, Inc. Devices, methods and systems for establishing supplemental blood flow in the circulatory system
US20110196191A1 (en) * 2010-02-11 2011-08-11 Circulite, Inc. Cannula lined with tissue in-growth material and method of using the same
US9504776B2 (en) 2010-02-11 2016-11-29 Circulite, Inc. Cannula lined with tissue in-growth material and method of using the same
US8768487B2 (en) 2010-02-11 2014-07-01 Circulite, Inc. Devices, methods and systems for establishing supplemental blood flow in the circulatory system
US9462962B2 (en) * 2010-04-13 2016-10-11 Biotronik Se & Co. Kg Implant and applicator
US20110251516A1 (en) * 2010-04-13 2011-10-13 Thomas Doerr Implant and applicator
US8814833B2 (en) 2010-05-19 2014-08-26 Tangent Medical Technologies Llc Safety needle system operable with a medical device
US8771230B2 (en) 2010-05-19 2014-07-08 Tangent Medical Technologies, Llc Integrated vascular delivery system
US9308354B2 (en) 2010-05-19 2016-04-12 Tangent Medical Technologies Llc Safety needle system operable with a medical device
US9827398B2 (en) 2010-05-19 2017-11-28 Tangent Medical Technologies, Inc. Integrated vascular delivery system
KR101212412B1 (en) 2010-08-24 2012-12-13 사회복지법인 삼성생명공익재단 Needle for Vats
US9833315B2 (en) 2011-08-11 2017-12-05 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9480559B2 (en) 2011-08-11 2016-11-01 Tendyne Holdings, Inc. Prosthetic valves and related inventions
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
US9855093B2 (en) 2012-07-12 2018-01-02 Bowa-Electronic Gmbh & Co. Kg Instrument for cutting body tissue
WO2014009420A1 (en) * 2012-07-12 2014-01-16 Bowa-Electronic Gmbh & Co. Kg Instrument for cutting body tissue
US9895221B2 (en) 2012-07-28 2018-02-20 Tendyne Holdings, Inc. Multi-component designs for heart valve retrieval device, sealing structures and stent assembly
US9675454B2 (en) 2012-07-30 2017-06-13 Tendyne Holdings, Inc. Delivery systems and methods for transcatheter prosthetic valves
WO2014055686A1 (en) * 2012-10-02 2014-04-10 Wallace Robert F Implant insertion system
CN104822410A (en) * 2012-10-02 2015-08-05 马修·Q·肖 Implant insertion system
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
US9597181B2 (en) 2013-06-25 2017-03-21 Tendyne Holdings, Inc. Thrombus management and structural compliance features for prosthetic heart valves
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves

Also Published As

Publication number Publication date Type
US20020052564A1 (en) 2002-05-02 application
EP1109496A2 (en) 2001-06-27 application
US20050245842A1 (en) 2005-11-03 application
WO2000012009A3 (en) 2000-06-29 application
US20020007130A1 (en) 2002-01-17 application
US6958044B2 (en) 2005-10-25 grant
US6540693B2 (en) 2003-04-01 grant
CA2341528C (en) 2010-01-05 grant
US8229553B2 (en) 2012-07-24 grant
US7264596B2 (en) 2007-09-04 grant
CA2341528A1 (en) 2000-03-09 application
JP2002523170A (en) 2002-07-30 application
EP1109496B1 (en) 2012-05-09 grant
US9216012B2 (en) 2015-12-22 grant
US20160058433A1 (en) 2016-03-03 application
US20120277626A1 (en) 2012-11-01 application
US20050143674A1 (en) 2005-06-30 application
US7329228B2 (en) 2008-02-12 grant
US20020087095A1 (en) 2002-07-04 application
WO2000012009A8 (en) 2000-08-03 application
WO2000012009A2 (en) 2000-03-09 application

Similar Documents

Publication Publication Date Title
US6036698A (en) Expandable ring percutaneous tissue removal device
US6673023B2 (en) Micro-invasive breast biopsy device
Liberman et al. Clip placement after stereotactic vacuum-assisted breast biopsy.
US6231518B1 (en) Intrapericardial electrophysiological procedures
US7416533B2 (en) Marking biopsy sites
US6165137A (en) Apparatus and method for localizing and removing tissue
US7160292B2 (en) Needle kit and method for microwave ablation, track coagulation, and biopsy
US4799495A (en) Localization needle assembly
US6758848B2 (en) Apparatus and method for accessing a body site
US6589252B2 (en) Breast surgery method and apparatus
US6840948B2 (en) Device for removal of tissue lesions
US20050143650A1 (en) Tissue marker and method and apparatus for deploying the marker
US6855140B2 (en) Method of tissue lesion removal
US20030097079A1 (en) Biopsy needle sheath
US5127916A (en) Localization needle assembly
US6142955A (en) Biopsy apparatus and method
US6056700A (en) Biopsy marker assembly and method of use
US6752767B2 (en) Localization element with energized tip
US20050165329A1 (en) Multiple biopsy collection device
US20030233101A1 (en) Plugged tip delivery tube for marker placement
US5810806A (en) Methods and devices for collection of soft tissue
US7347829B2 (en) Introduction system for minimally invasive surgical instruments
US6638234B2 (en) Sentinel node location and biopsy
US7488295B2 (en) Tissue acquisition system and method of use
US6019733A (en) Biopsy apparatus and method