US20050187625A1 - Vertebral body replacement apparatus and method - Google Patents

Vertebral body replacement apparatus and method Download PDF

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Publication number
US20050187625A1
US20050187625A1 US11031362 US3136205A US2005187625A1 US 20050187625 A1 US20050187625 A1 US 20050187625A1 US 11031362 US11031362 US 11031362 US 3136205 A US3136205 A US 3136205A US 2005187625 A1 US2005187625 A1 US 2005187625A1
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US11031362
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Howard Wolek
Francesco Larosa
Jeffrey Kozak
Mark Lorenz
Michael Zindrick
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Blackstone Medical Inc
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Blackstone Medical Inc
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    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0033Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2220/00Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2220/0025Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
    • A61F2220/0041Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements using additional screws, bolts, dowels or rivets, e.g. connecting screws
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/006Additional features; Implant or prostheses properties not otherwise provided for modular
    • A61F2250/0063Nested prosthetic parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0082Additional features; Implant or prostheses properties not otherwise provided for specially designed for children, e.g. having means for adjusting to their growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0098Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers

Abstract

Various embodiments of the present invention relate to an apparatus for vertebral body replacement and methods associated therewith. In one embodiment, a vertebral body replacement apparatus may be used to correct and stabilize the spine (e.g., the thoracolumbar spine (T1-L5)). In another embodiment, a vertebral body (e.g., a diseased and/or damaged vertebral body) that has been resected or excised (e.g., for the treatment of a tumor or trauma) may be replaced (with the height of the resected or excised vertebral body being substantially replaced and restored by the apparatus of the present invention).

Description

    CROSS-REFERENCE TO RELATED APPLICATIONS
  • This application is a continuation in part of U.S. application Ser. No. 10/968,586 filed Oct. 19, 2004, which claims the benefit under 35 U.S.C. 119(e) of U.S. Provisional Application Ser. No. 60/512,716, filed Oct. 20, 2003.
  • FIELD OF THE INVENTION
  • Various embodiments of the present invention relate to an apparatus for vertebral body replacement and methods associated therewith.
  • In one embodiment, a vertebral body replacement apparatus may be used to correct and stabilize the spine (e.g., the thoracolumbar spine (T1-L5)).
  • In another embodiment, a vertebral body (e.g., a diseased and/or damaged vertebral body) that has been resected or excised (e.g., for the treatment of a tumor or trauma) may be replaced (with the height of the resected or excised vertebral body being substantially replaced and restored by the apparatus of the present invention).
  • BACKGROUND OF THE INVENTION
  • Examples of various patent documents in the spinal implant area include the following:
  • U.S. Pat. No. 5,192,327 to Brantigan relates to a surgical prosthetic implant for vertebrae. More particularly, surgical prosthetic modular implants used singularly or stacked together are provided to support and fuse together adjacent vertebrae or to totally or partially replace one or more vertebrae in a vertebral column. The implants are rigid annular plugs, dimensionally similar to normal vertebral bodies, have simplified oval or hemi-oval shapes with ridged faces to engage adjacent vertebral bodies to resist displacement and allow bone ingrowth and fusion and to interdigitate with the ridges of an adjacent plug for modular stacking to allow variability of ultimate implant height. The implants can be provided in sets of different thicknesses and are internally grooved to receive an upstanding connecting bar to bind together the individual stacked implants into a stable unit. The annular implants have ample spaces to allow ingrowth of blood capillaries and packing of bone graft and are preferably made of a radiolucent material, preferably biocompatible carbon fiber reinforced polymers or are alternately made of traditional orthopaedic implant materials such as nickel, chromium, cobalt, stainless steel or titanium.
  • U.S. Pat. No. 5,397,364 to Kozak et al. relates to an anterior interbody fusion device. More particularly, an interbody fusion device includes a pair of lateral spacers and a pair of central spacers, each sized for percutaneous introduction through a disc resection portal in the disc annulus. Each of the lateral spacers includes opposing side faces defining a channel therein, while each of the central spacers includes arms at their opposite ends configured to be received within a channel of a corresponding lateral spacer. The arms and channels are interlocking to prevent separation of the components once assembled within the intradiscal space. The assembly of the central and lateral spacers defines a cavity therebetween for insertion of bone graft material. The central and lateral spacers are configured so that the bone graft cavity is oriented over the weakest, but most vascular and biologically active, bone of the vertebral body, while the lateral spacers are situated adjacent the disc annulus and over the strongest vertebral bone.
  • U.S. Pat. No. 6,159,211 to Boriani et al. relates to a stackable cage system for corpectomy/vertebrectomy. More particularly, surgical prosthetic modular devices used singularly or stacked together are provided for use to replace excised vertebral tissue. The devices are rigid plugs, dimensionally similar to normal vertebral bodies, and have ridged faces to engage adjacent vertebral bodies or to interdigitate when stacked. Ridges extend in both the medial/lateral and anterior/posterior directions to prevent slipping in the anterior/posterior and medial/lateral directions respectively. A locking screw may be used to secure a stack to form a singular rigid prosthetic device. The devices are also provided with a plurality of threaded openings. In the method of this invention, a device is used to replace excised vertebral tissue, threaded bolts are inserted into the threaded openings, and other spine stabilization devices are attached to the bolts. In corporectomies, the device can be bolted to a plate, which in turn is fixed to adjacent vertebrae. In spondylectomies, the device can be fixed to a series of posteriorly placed rods.
  • U.S. Pat. No. 6,468,311 to Boyd et al. relates to a modular interbody fusion implant. More particularly, an interbody fusion device for engagement between vertebrae includes a pair of lateral spacers for spacing the vertebrae, and a connecting member adapted to couple together the lateral spacers when inserted between the vertebrae. The connecting member, individual lateral spacers, or the entire spinal spacer can be made of bone in order to promote fusion of the vertebrae. The modular construction permits use of bone segments otherwise unsuitable due to size or strength in stable fusion devices.
  • U.S. Patent Application No. 2003/0040799 in the name of Boyd et al. relates to a modular interbody fusion implant. More particularly, an interbody fusion device for engagement between vertebrae includes a pair of lateral spacers for spacing the vertebrae, and a connecting member adapted to couple together the lateral spacers when inserted between the vertebrae. The connecting member, individual lateral spacers, or the entire spinal spacer can be made of bone in order to promote fusion of the vertebrae. The modular construction permits use of bone segments otherwise unsuitable due to size or strength in stable fusion devices.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 shows a perspective view of one embodiment of a vertebral body replacement implant assembly according to the present invention;
  • FIG. 2 shows another view of the implant assembly of FIG. 1 as it would look outside of the body;
  • FIGS. 3A and 3B show exploded perspective views of the implant assembly of FIGS. 1 and 2 (FIG. 3A shows an embodiment of the implant assembly from one angle and FIG. 3B shows an embodiment of the implant assembly from another angle);
  • FIG. 4 shows a perspective view of an endplate type component of an implant assembly according to an embodiment of the present invention;
  • FIG. 5 shows a perspective view of a non-lordotic lateral spacer type component of an implant assembly according to an embodiment of the present invention;
  • FIG. 6 shows a perspective view of a lordotic lateral spacer type component of an implant assembly according to an embodiment of the present invention;
  • FIG. 7 shows a plan view of an implant assembly according to an embodiment of the present invention;
  • FIG. 8 shows section A-A of FIG. 7;
  • FIG. 9 shows Detail B of FIG. 8;
  • FIG. 10 shows a plan view of another embodiment of the present invention;
  • FIGS. 11-14 show perspective views of other embodiments of the present invention;
  • FIGS. 15 and 16 show, respectively, a perspective view and an exploded perspective view of another embodiment of the present invention;
  • FIGS. 17A-17G show perspective views of various components according to an embodiment of the present invention;
  • FIGS. 18, 19A, 19B, 20A, 20B and 21 show perspective views of various implant assemblies using the components of FIGS. 17A-17G;
  • FIGS. 22A-22E show various views of an implant assembly using the components of FIGS. 17A-17G;
  • FIG. 23 shows a perspective view of another embodiment of a vertebral body replacement implant assembly according to the present invention;
  • FIG. 24 shows another view of the implant assembly of FIG. 23 as it would look outside of the body;
  • FIG. 25 shows an exploded perspective view of the implant assembly of FIGS. 23 and 24;
  • FIG. 26 shows a perspective view of an endplate type component of an implant assembly according to an embodiment of the present invention;
  • FIG. 27 shows a perspective view of a non-lordotic lateral spacer type component of an implant assembly according to an embodiment of the present invention;
  • FIG. 28 shows a perspective view of a lordotic lateral spacer type component of an implant assembly according to an embodiment of the present invention;
  • FIG. 29 shows a plan view of an implant assembly according to an embodiment of the present invention;
  • FIG. 30 shows section B-B of FIG. 29; and
  • FIG. 31 shows Detail C of FIG. 30.
  • Among those benefits and improvements that have been disclosed, other objects and advantages of this invention will become apparent from the following description taken in conjunction with the accompanying figures. The figures constitute a part of this specification and include illustrative embodiments of the present invention and illustrate various objects and features thereof.
  • DETAILED DESCRIPTION OF THE INVENTION
  • Detailed embodiments of the present invention are disclosed herein; however, it is to be understood that the disclosed embodiments are merely illustrative of the invention that may be embodied in various forms. In addition, each of the examples given in connection with the various embodiments of the invention are intended to be illustrative, and not restrictive. Further, the figures are not necessarily to scale, some features may be exaggerated to show details of particular components. Therefore, specific structural and functional details disclosed herein are not to be interpreted as limiting, but merely as a representative basis for teaching one skilled in the art to variously employ the present invention.
  • Referring now to FIG. 1, one embodiment of a vertebral body replacement implant assembly according to the present invention is shown. As seen in this FIG. 1, Implant Assembly 101 may be implanted between First Vertebra 103 a and Second Vertebra 103 b (FIG. 2 shows another view of Implant Assembly 101 as it would look outside of the body). Of note, Implant Assembly 101 may be formed of a number of components fitted together.
  • More particularly, as seen in FIGS. 3A and 3B, Implant Assembly 101 may be formed of, for example, four components: (a) First Endplate 301 (e.g., a top Endplate), Second Endplate 303 (e.g., a bottom Endplate), First Lateral Spacer 305 and Second Lateral Spacer 307.
  • First Endplate 301 may include: First Offset Aperture 301 a (e.g., offset relative to a centerline of Endplate 301); Second Offset Aperture 301 b (e.g., offset relative to a centerline of Endplate 301); Protrusions 301 c and 301 d (these Protrusions are seen most clearly in FIG. 3B; although in this embodiment there are four such Protrusions (two adjacent First Offset Aperture 301 a and two adjacent Second Offset Aperture 301 b) any number of protrusions may be utilized); Insertion Tool Mating Aperture 301 e (for mating with an insertion tool (not shown)); and various grooves disposed along the top surface (the grooves are not separately numbered in the Figs.).
  • Likewise, Second Endplate 303 may include: First Offset Aperture 303 a (e.g., offset relative to a centerline of Endplate 303); Second Offset Aperture 303 b (e.g., offset relative to a centerline of Endplate 303); Protrusions 303 c-303 f; Insertion Tool Mating Aperture 303 g (for mating with an insertion tool (not shown)); and various grooves disposed along the bottom surface (the grooves are not separately numbered in the Figs.).
  • Further, First Lateral Spacer 305 may include: Main Aperture 305 a (which may at least partially line-up with First Offset Aperture 301 a and First Offset Aperture 303 a; various Auxiliary Apertures (not separately numbered in the Figs.); and various grooves disposed along the top surface and the bottom surface (the grooves are not separately numbered in the Figs.).
  • Likewise, Second Lateral Spacer 307 may include: Main Aperture 307 a (which may at least partially line-up with Second Offset Aperture 301 b and Second Offset Aperture 303 b; various Auxiliary Apertures (not separately numbered in the Figs.); and various grooves disposed along the top surface and the bottom surface (the grooves are not separately numbered in the Figs.).
  • Of note, the embodiments of FIGS. 3A and 3B are similar, with the main differences being the shape of the internal centerline bosses on the inner faces of the First Endplate and Second Endplate and the fact that the Protrusions in the embodiment of FIG. 3A are essentially featureless (such that they provide lateral alignment/support) while the Protrusions of the embodiment of FIG. 3B provide locking features such as the ridges shown in the Fig. but not separately numbered (such that the ridges cooperate with mating indentations (shown in the Fig. but not separately numbered) in the First Lateral Spacer and the Second Lateral Spacer to provide both lateral alignment/support as well as up-down locking (e.g., removable locking) of the components). In another example (which example is intended to be illustrative and not restrictive), a tab and slot system may be utilized for locking.
  • Of further note, Implant Assembly 101 may provide for bony ingrowth and/or may be packed with bone matter. This may be accomplished via the hollow fenestrated design of the components (e.g., via First Offset Aperture 301 a; Second Offset Aperture 301 b; First Offset Aperture 303 a; Second Offset Aperture 303 b; Main Aperture 305 a; Main Aperture 307 a; and/or the various Auxiliary Apertures) and/or the hollow fenestrated design of the finished implant assembly (e.g., via the space(s) between First Lateral Spacer 305 and Second Lateral Spacer 307 at each end of the finished implant assembly).
  • In one set of examples (which examples are intended to be illustrative and not restrictive), Implant Assembly 101 may be provided in two footprint sizes. The “small” footprint may measure, for example, 28 mm wide×23 mm length (in this example each “small” footprint size Endplate may be 28 mm wide×23 mm length, and each Lateral Spacer may be 8 mm wide×23 mm length). The “large” footprint may measure, for example, 35 mm wide×28 mm length (in this example each “large” footprint size Endplate may be 35 mm wide×28 mm length, and each Lateral Spacer may be 8 mm wide×28 mm length). One or both footprint sizes may be available in height ranges from, for example, 12 mm to 60 mm (in increments of one millimeter, for example).
  • Reference will now be made to Tables 1-3, below, which identify example thicknesses of the components of a “large” implant assembly (of course, these examples are intended to be illustrative and not restrictive). More particularly, Table 1 identifies example thicknesses of a “large” End Plate (see, e.g., FIG. 4 for a perspective view of this type of component), Table 2 identifies example thicknesses of a “large” Non-Lordotic Lateral Spacer (see, e.g., FIG. 5 for a perspective view of this type of component) and Table 3 identifies example thicknesses of a “large” Lordotic Lateral Spacer (see, e.g., FIG. 6 for a perspective view of this type of component).
    TABLE 1
    (All measurements in mm)
    2 3 4
  • TABLE 2
    (All measurements in mm)
    8 10 12 14 16 21 26 31 36 41 46 51 56
  • TABLE 3
    (All measurements in mm)
    8 10 12 14 16 21 26 31 36 41 46 51 56
  • Reference will now be made to Tables 4-6, below, which identify example thicknesses of the components of a “small” implant assembly (of course, these examples are intended to be illustrative and not restrictive). More particularly, Table 4 identifies example thicknesses of a “small” End Plate (see, e.g., FIG. 4 for a perspective view of this type of component), Table 5 identifies example thicknesses of a “small” Non-Lordotic Lateral Spacer (see, e.g., FIG. 5 for a perspective view of this type of component) and Table 6 identifies example thicknesses of a “small” Lordotic Lateral Spacer (see, e.g., FIG. 6 for a perspective view of this type of component).
    TABLE 4
    (All measurements in mm)
    2 3 4
  • TABLE 5
    (All measurements in mm)
    8 10 12 14 16 21 26 31 36 41 46 51 56
  • TABLE 6
    (All measurements in mm)
    8 10 12 14 16 21 26 31 36 41 46 51 56
  • Referring now to construction of the implant assembly from its constituent components, it is noted that in one embodiment such construction may occur outside of the patient's body (e.g., outside of the wound). More particularly, after determining the correct height, footprint and/or lordotic requirement of the implant assembly, the surgeon may then select one or more lateral spacers (e.g., two) and/or one or more endplates (e.g., two) that would meet the requirements (e.g., a 30 mm tall implant assembly may utilize two lateral spacers of 26 mm tall and two 2 mm thick endplates). The components may be assembled by snapping the lateral spacers onto a first endplate and then snapping a second endplate onto the two lateral spacers. Such snapping construction may be carried out, for example, using a lip and undercut arrangement (see FIG. 7 (showing a plan view of an implant assembly according to an embodiment of the present invention), FIG. 8 (showing section A-A of FIG. 7), and FIG. 9 (showing Detail B of FIG. 8)). More particularly, with regard to such snapping construction, attention is directed to the features of FIG. 9 which show the undercut in the lateral spacer and the tapered lip on the endplate (wherein an interference may exist in the assembly until the tapered lip reaches the undercut and snaps into place creating a lock).
  • In another embodiment, some or all of the components may include or be made essentially entirely from polyetheretherketone (e.g., PEEK Optima). Of note, this PEEK polymer material has radiolucent properties, which may aid the surgeon in determining if fusion (e.g., in the operative site) has occurred. Since such PEEK material is essentially transparent to x-rays, markers (e.g., markers made of titanium) may be inserted into one or more of the components to give a surgeon a visual aid in determining the location of the component and/or entire implant assembly (e.g., both inter and postoperatively).
  • In another embodiment, Indications relating to use of the present invention may include (but not be limited to):
      • For use in thoracolumbar spine (i.e., T1 to L5) to replace a vertebral body (e.g., a diseased vertebral body) resected or excised (e.g., for the treatment of tumor(s)) to achieve anterior decompression of the spinal cord and neural tissues, and to restore the height of a collapsed vertebral body.
      • For treating fracture(s) of the thoracic and/or lumbar spine.
      • To restore the biomechanical integrity of the anterior, middle, and/or posterior spinal column (e.g., even in the absence of fusion for a prolonged period).
      • For use with supplemental internal fixation. Such supplemental internal fixation may include (but not be limited to) any appropriate screws, rods, staples, washers, cross connectors, and/or posterior hooks.
  • In another embodiment, Contraindications relating to use of the present invention may include (but not be limited to):
      • Morbid obesity
      • Mental illness
      • Alcoholism and/or drug abuse
      • Pregnancy
      • Mental sensitivity/allergies
      • Severe osteopenia
      • Patients unwilling or unable to follow post-operative care instructions
      • Certain circumstances not identified above as an Indication (e.g., as identified by any appropriate care giver)
  • In another embodiment, one or more of the components and/or the implant assembly may have a tapered lead-in (e.g., for easy insertion).
  • In another embodiment, each lateral spacer may be capable of supporting the vertebral column.
  • In another embodiment, the textured surface of the components and/or the implant assembly may allow for easy insertion and/or resistance to expulsion (see FIGS. 10-14 for additional textured surface examples (which examples are intended to be illustrative and not restrictive)).
  • In another embodiment, multiple lateral spacer type components may be assembled in a “bridge” configuration (see FIGS. 15 and 16, for example).
  • In another embodiment, the components may be assembled as desired (see FIGS. 17A-17G, 18, 19A, 19B, 20A, 20B, 21 and 22A-22E, for example).
  • Referring now to FIG. 23, another embodiment of a vertebral body replacement implant assembly according to the present invention is shown. As seen in this FIG. 23, Implant Assembly 2301 may be implanted between First Vertebra 2303 a and Second Vertebra 2303 b (FIG. 24 shows another view of Implant Assembly 2301 as it would look outside of the body). Of note, Implant Assembly 2301 may be formed of a number of components fitted together.
  • More particularly, as seen in FIG. 25, Implant Assembly 2301 may be formed of, for example, four components: (a) First Endplate 2501 (e.g., a top Endplate), Second Endplate 2503 (e.g., a bottom Endplate), First Lateral Spacer 2505 and Second Lateral Spacer 2507.
  • First Endplate 2501 may include: First Offset Aperture 2501 a (e.g., offset relative to a centerline of Endplate 2501); Second Offset Aperture 2501 b (e.g., offset relative to a centerline of Endplate 2501); Protrusions 2501 c and 2501 d (these Protrusions are not seen in this Fig. but are similar to the Protrusions of Second Endplate 2503 discussed below—although in this embodiment there are four such Protrusions (two adjacent First Offset Aperture 2501 a and two adjacent Second Offset Aperture 2501 b) any number of protrusions may be utilized); Insertion Tool Mating Aperture 2501 e (for mating with an insertion tool (not shown)); and various grooves disposed along the top surface (the grooves are not separately numbered in the Figs.).
  • Likewise, Second Endplate 2503 may include: First Offset Aperture 2503 a (e.g., offset relative to a centerline of Endplate 2503); Second Offset Aperture 2503 b (e.g., offset relative to a centerline of Endplate 2503); Protrusions 2503 c-2503 f; Insertion Tool Mating Aperture 2503 g (for mating with an insertion tool (not shown)); and various grooves disposed along the bottom surface (the grooves are not separately numbered in the Figs.).
  • Further, First Lateral Spacer 2505 may include: Main Aperture 2505 a (which may at least partially line-up with First Offset Aperture 2501 b and First Offset Aperture 2503 b; various Auxiliary Apertures (not separately numbered in the Figs.); and various grooves disposed along the top surface and the bottom surface (the grooves are not separately numbered in the Figs.).
  • Likewise, Second Lateral Spacer 2507 may include: Main Aperture 2507 a (which may at least partially line-up with Second Offset Aperture 2501 a and Second Offset Aperture 2503 a; various Auxiliary Apertures (not separately numbered in the Figs.); and various grooves disposed along the top surface and the bottom surface (the grooves are not separately numbered in the Figs.).
  • Of note, the embodiments of FIGS. 25 and 3A/3B are similar, with the main differences being that in the embodiment of FIG. 25 each of First Endplate 2501 and Second Endplate 2503 includes pockets into which each of First Lateral Spacer 2505 and Second Lateral Spacer 2507 fits (Pockets 2503 h and 2503 i are individually identified in FIG. 25 in connection with Second Endplate 2503—First Endplate 2501 has similar pockets which are not seen in this view).
  • In one example (which example is intended to be illustrative and not restrictive), the pockets may provide (either alone or in combination with the protrusions) lateral alignment/support of the components. In another example (which example is intended to be illustrative and not restrictive), the pockets may provide (either alone or in combination with the protrusions) both lateral alignment/support of the components as well as up-down locking (e.g., removable locking) of the components. In another example (which example is intended to be illustrative and not restrictive), a tab and slot system may be utilized for locking.
  • Of further note, Implant Assembly 2301 may provide for bony ingrowth and/or may be packed with bone matter. This may be accomplished via the hollow fenestrated design of the components (e.g., via First Offset Aperture 2501 a; Second Offset Aperture 2501 b; First Offset Aperture 2503 a; Second Offset Aperture 2503 b; Main Aperture 2505 a; Main Aperture 2507 a; and/or the various Auxiliary Apertures) and/or the hollow fenestrated design of the finished implant assembly (e.g., via the space(s) between First Lateral Spacer 2505 and Second Lateral Spacer 2507 at each end of the finished implant assembly).
  • Referring now to FIGS. 26-28, it is noted that these Figs. show, respectively, a perspective view of an endplate according to an embodiment of the present invention, a perspective view of a non-lordotic lateral spacer according to an embodiment of the present invention and a perspective view of a lordotic lateral spacer according to an embodiment of the present invention.
  • Referring now to construction of the implant assembly it is noted, as discussed above, that the lateral spacers may be snapped onto a first endplate and then a second endplate may be snapped onto the two lateral spacers. Such snapping construction may be carried out, for example, using a lip and undercut arrangement (see FIG. 29 (showing a plan view of an implant assembly according to an embodiment of the present invention), FIG. 30 (showing section B-B of FIG. 29), and FIG. 31 (showing Detail C of FIG. 30)). More particularly, with regard to such snapping construction, attention is directed to the features of FIG. 31 which show the undercut in the lateral spacer and the tapered lip on the endplate (wherein an interference may exist in the assembly until the tapered lip reaches the undercut and snaps into place creating a lock).
  • While a number of embodiments of the present invention have been described, it is understood that these embodiments are illustrative only, and not restrictive, and that many modifications may become apparent to those of ordinary skill in the art. For example, an implant assembly according to the present invention may be tested in accordance with ASTM F 2077-03 “Test Methods For Intervertebral Body Fusion Devices” (or a modified version thereof) and/or the FDA's Sep. 27, 2000 “Guidance for Spinal Systems 510(k)'s. Further, the lordotic angle may be any desired angle (e.g., 4°-8°). Further still, one or more components may be used separately from an implant assembly (e.g., one or more of the lateral spacers (non-lordotic and/or lordotic) may be implanted directly into the spine without use of a top and/or bottom endplate). Further still, the various components may take different shapes as desired and the various features may take on various specifics as desired (e.g., the various apertures may be of any desired number and/or shape). Further still, the apparatus (and/or its components) may, of course, have any desired dimensions (e.g., for any desired patient—man, woman or child). Further still, the apparatus (and/or its components) may be provided in a “line” or “family” of devices (e.g., small, medium and large; adult, child; male, female). Further still, the apparatus (and/or its components) may be provided in standard sizes. Further still, any desired locking mechanism(s) may be used to hold the various components together and/or in desired alignment. Further still, such locking may be capable of being unlocked (e.g., a mechanism and/or tool may be provided for unlocking the various components). Further still, lateral spacers(s) may be disposed adjacent one or more central spacers. Further still, any steps relating to manufacture and/or use may be performed in any desired order.

Claims (31)

  1. 1. A vertebral body replacement apparatus for placement between a first vertebra and a second vertebra, comprising:
    a first endplate including a generally outward facing surface for contacting at least a portion of a lower face of the first vertebra and a generally inward facing surface including thereon at least two pockets and at least two protrusions, wherein at least one protrusion is disposed within each of the pockets;
    a second endplate including a generally outward facing surface for contacting at least a portion of an upper face of the second vertebra and a generally inward facing surface including thereon at least two pockets and at least two protrusions, wherein at least one protrusion is disposed within each of the pockets;
    a first lateral spacer including at least one aperture; and
    a second lateral spacer including at least one aperture;
    wherein, when the first and second lateral spacers are disposed between the first and second endplates such that the first endplate is above the first and second lateral spacers and the second endplate is below the first and second lateral spacers, a first pair of opposed pockets of the first and second endplates are configured to receive therein at least a part of the first lateral spacer and a second pair of opposed pockets of the first and second endplates are configured to receive therein at least a part of the second lateral spacer; and
    wherein the aperture of the first lateral spacer is configured to receive at least one of the protrusions of each of the first and second endplates when the first lateral spacer is received within the first pair of pockets and the aperture of the second lateral spacer is configured to receive at least one of the protrusions of each of the first and second endplates when the second lateral spacer is received within the second pair of pockets.
  2. 2. The apparatus of claim 1, wherein at least one of: (a) the mating of each of the protrusions with a respective one of the apertures provides lateral alignment between each of the first endplate, the second endplate, the first lateral spacer and the second lateral spacer; and (b) the mating of each of the lateral spacers with a respective pocket provides lateral alignment between each of the first endplate, the second endplate, the first lateral spacer and the second lateral spacer.
  3. 3. The apparatus of claim 2, wherein at least one of the protrusions and at least one of a respective one of the apertures includes a locking mechanism for locking the protrusion in the aperture.
  4. 4. The apparatus of claim 3, wherein the locking mechanism of the protrusion and the locking mechanism of the aperture are configured to permit unlocking thereof.
  5. 5. The apparatus of claim 4, wherein the locking mechanism of the protrusion comprises a raised ridge and the locking mechanism of the aperture comprises an indentation.
  6. 6. The apparatus of claim 4, wherein the locking mechanism of the protrusion comprises a tab and the locking mechanism of the aperture comprises a slot.
  7. 7. The apparatus of claim 1, wherein the aperture of the first lateral spacer extends through the first lateral spacer and the aperture of the second lateral spacer extends through the second lateral spacer.
  8. 8. The apparatus of claim 1, wherein each of the first and second lateral spacers includes a respective upper aperture adjacent the generally inward facing surface of the first endplate for receiving at least one of the protrusions of the first endplate and each of the first and second lateral spacers includes a respective lower aperture adjacent the generally inward facing surface of the second endplate for receiving at least one of the protrusions of the second endplate.
  9. 9. The apparatus of claim 1, wherein each of the first and second lateral spacers has a lordotic angle between about 0-8 degrees.
  10. 10. The apparatus of claim 1, wherein the generally outward facing surface of the first endplate is textured and the generally outward facing surface of the second endplate is textured.
  11. 11. The apparatus of claim 10, wherein the texture is configured to resist expulsion of the apparatus from between the first and second vertebrae.
  12. 12. The apparatus of claim 10, wherein the texture is configured to aid in insertion of the apparatus between the first and second vertebrae.
  13. 13. The apparatus of claim 10, wherein the texture is configured to aid in permitting bony ingrowth from the first and second vertebrae.
  14. 14. The apparatus of claim 10, wherein the texture is selected from the group including: (a) teeth; (b) grooves; and (c) ridges.
  15. 15. The apparatus of claim 1, wherein the first endplate, the second endplate, the first lateral spacer and the second lateral spacer are configured to define at least one hollow area when the first and second lateral spacers are disposed between the first and second endplates such that the first endplate is above the first and second lateral spacers and the second endplate is below the first and second lateral spacers.
  16. 16. The apparatus of claim 15, wherein the hollow area is configured to aid in permitting bony ingrowth from the first and second vertebrae.
  17. 17. The apparatus of claim 1, wherein at least one of the first endplate, the second endplate, the first lateral spacer and the second lateral spacer comprises polyetheretherketone.
  18. 18. The apparatus of claim 1, wherein at least one of the first endplate, the second endplate, the first lateral spacer and the second lateral spacer includes a marker comprising a material which is substantially opaque to x-rays.
  19. 19. The apparatus of claim 1, further comprising at least one additional spacer disposed laterally between the first lateral spacer and the second lateral spacer.
  20. 20. The apparatus of claim 1, further comprising a mechanism for connecting the apparatus to a means for supplemental fixation.
  21. 21. The apparatus of claim 20, wherein the means for supplemental fixation is selected from the group including: (a) one or more screws; (b) one or more rods; (c) one or more staples; (d) one or more washers; (e) one or more cross connectors; and (f) one or more hooks.
  22. 22. A method of constructing a vertebral body replacement apparatus for placement between a first vertebra and a second vertebra, comprising:
    selecting a first endplate including a generally outward facing surface for contacting at least a portion of a lower face of the first vertebra and a generally inward facing surface including thereon at least two pockets and at least two protrusions, wherein at least one protrusion is disposed within each of the pockets;
    selecting a second endplate including a generally outward facing surface for contacting at least a portion of an upper face of the second vertebra and a generally inward facing surface including thereon at least two pockets and at least two protrusions, wherein at least one protrusion is disposed within each of the pockets;
    selecting a first lateral spacer including at least one aperture;
    selecting a second lateral spacer including at least one aperture; and
    placing the first and second lateral spacers between the first and second endplates such that the first endplate is above the first and second lateral spacers and the second endplate is below the first and second lateral spacers and such that a first pair of opposed pockets of the first and second endplates receive therein at least a part of the first lateral spacer and a second pair of opposed pockets of the first and second endplates receive therein at least a part of the second lateral spacer;
    wherein the aperture of the first lateral spacer receives at least one of the protrusions of each of the first and second endplates when the first lateral spacer is received within the first pair of pockets and the aperture of the second lateral spacer receives at least one of the protrusions of each of the first and second endplates when the second lateral spacer is received within the second pair of pockets.
  23. 23. The method of claim 22, wherein at least one of: (a) the mating of each of the protrusions with a respective one of the apertures provides lateral alignment between each of the first endplate, the second endplate, the first lateral spacer and the second lateral spacer; and (b) the mating of each of the lateral spacers with a respective pocket provides lateral alignment between each of the first endplate, the second endplate, the first lateral spacer and the second lateral spacer.
  24. 24. The method of claim 23, wherein at least one of the protrusions and at least one of a respective one of the apertures includes a locking mechanism for locking the protrusion in the aperture.
  25. 25. The method of claim 24, wherein the locking mechanism of the protrusion and the locking mechanism of the aperture are configured to permit unlocking thereof.
  26. 26. The method of claim 22, wherein the aperture of the first lateral spacer extends through the first lateral spacer and the aperture of the second lateral spacer extends through the second lateral spacer.
  27. 27. The method of claim 22, wherein each of the first and second lateral spacers includes a respective upper aperture adjacent the generally inward facing surface of the first endplate for receiving at least one of the protrusions of the first endplate and each of the first and second lateral spacers includes a respective lower aperture adjacent the generally inward facing surface of the second endplate for receiving at least one of the protrusions of the second endplate.
  28. 28. The method of claim 22, wherein the steps are carried out in the order recited.
  29. 29. A method of stabilizing a spine, comprising:
    selecting, for a vertebral body replacement apparatus, a first endplate including a generally outward facing surface for contacting at least a portion of a lower face of the first vertebra and a generally inward facing surface including thereon at least two pockets and at least two protrusions, wherein at least one protrusion is disposed within each of the pockets;
    selecting, for the vertebral body replacement apparatus, a second endplate including a generally outward facing surface for contacting at least a portion of an upper face of the second vertebra and a generally inward facing surface including thereon at least two pockets and at least two protrusions, wherein at least one protrusion is disposed within each of the pockets;
    selecting, for the vertebral body replacement apparatus, a first lateral spacer including at least one aperture;
    selecting, for the vertebral body replacement apparatus, a second lateral spacer including at least one aperture;
    constructing the vertebral body replacement apparatus by placing the first and second lateral spacers between the first and second endplates such that the first endplate is above the first and second lateral spacers and the second endplate is below the first and second lateral spacers, such that a first pair of opposed pockets of the first and second endplates receive therein at least a part of the first lateral spacer and a second pair of opposed pockets of the first and second endplates receive therein at least a part of the second lateral spacer, such that the aperture of the first lateral spacer receives at least one of the protrusions of each of the first and second endplates when the first lateral spacer is received within the first pair of pockets and such that the aperture of the second lateral spacer receives at least one of the protrusions of each of the first and second endplates when the second lateral spacer is received within the second pair of pockets; and
    placing the vertebral body replacement apparatus between the first and second vertebrae.
  30. 30. The method of claim 29, wherein the vertebral body replacement apparatus is configured to be placed in one of the thoracic and lumbar spinal regions.
  31. 31. The method of claim 29, wherein the steps are carried out in the order recited.
US11031362 2003-10-20 2005-01-07 Vertebral body replacement apparatus and method Abandoned US20050187625A1 (en)

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Cited By (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050171608A1 (en) * 2004-01-09 2005-08-04 Sdgi Holdings, Inc. Centrally articulating spinal device and method
US20060178746A1 (en) * 2005-02-10 2006-08-10 Depuy Spine, Inc. Intervertebral prosthetic disc and method for installing using a guidewire
US20070093898A1 (en) * 2005-09-26 2007-04-26 Schwab Frank J Transforaminal hybrid implant
US20070233247A1 (en) * 2005-09-26 2007-10-04 Schwab Frank J Hybrid intervertebral spinal fusion implant
US20070233248A1 (en) * 2005-09-26 2007-10-04 Schwab Frank J Anterior hybrid implant
US20070239278A1 (en) * 2006-04-06 2007-10-11 Sdgi Holdings, Inc. Intervertebral prosthetic devices and methods
WO2008065450A1 (en) 2006-11-29 2008-06-05 Surgicraft Limited Orthopaedic implants and prostheses
US20080140204A1 (en) * 2006-12-07 2008-06-12 Warsaw Orthopedic, Inc. Vertebral Implant Systems and Methods of Use
US20090306715A1 (en) * 2006-02-01 2009-12-10 Jackson Benjamin L Interspinous process spacer
US7811326B2 (en) 2006-01-30 2010-10-12 Warsaw Orthopedic Inc. Posterior joint replacement device
US20110087329A1 (en) * 2009-10-13 2011-04-14 Nicholas Poulos Lumbar implant
US20110160860A1 (en) * 2009-12-31 2011-06-30 Rhausler, Inc. Cervical spacer
US7976549B2 (en) 2006-03-23 2011-07-12 Theken Spine, Llc Instruments for delivering spinal implants
US7988695B2 (en) 2005-12-21 2011-08-02 Theken Spine, Llc Articulated delivery instrument
US8372150B2 (en) 2004-01-09 2013-02-12 Warsaw Orthpedic, Inc. Spinal device and method
US20130178939A1 (en) * 2009-10-13 2013-07-11 Nicholas Poulos Expandable interbody implant and method
US8506636B2 (en) 2006-09-08 2013-08-13 Theken Spine, Llc Offset radius lordosis
US8574301B2 (en) * 2004-03-29 2013-11-05 Nuvasive, Inc. Systems and methods for spinal fusion
US20140100663A1 (en) * 2006-02-27 2014-04-10 DePuy Synthes Products, LLC Intervertebral implant with fixation geometry
US8864832B2 (en) 2007-06-20 2014-10-21 Hh Spinal Llc Posterior total joint replacement
US9168152B2 (en) 2008-02-29 2015-10-27 Nuvasive, Inc. Implants and methods for spinal fusion
US9186261B2 (en) 2007-03-07 2015-11-17 Nuvasive, Inc. System and methods for spinal fusion
US9198765B1 (en) 2011-10-31 2015-12-01 Nuvasive, Inc. Expandable spinal fusion implants and related methods
US9211195B2 (en) 2009-10-13 2015-12-15 Nicholas Poulos Expandable interbody implant and method
US9211193B2 (en) 2013-08-30 2015-12-15 Aesculap Implant Systems, Llc Prosthesis, system and method
USD754346S1 (en) 2009-03-02 2016-04-19 Nuvasive, Inc. Spinal fusion implant
US9326861B2 (en) 2012-08-03 2016-05-03 Globus Medical, Inc. Stabilizing joints
US9358127B2 (en) 2008-09-02 2016-06-07 Globus Medical, Inc. Intervertebral fusion implant
US9364340B2 (en) 2013-03-05 2016-06-14 Globus Medical, Inc. Low profile plate
US9408718B2 (en) 2009-12-31 2016-08-09 Rhausler, Inc. Inter-vertebral implant with angled plate
US9456906B2 (en) 2013-03-15 2016-10-04 Globus Medical, Inc. Expandable intervertebral implant
US9474622B2 (en) 2013-03-15 2016-10-25 Globus Medical, Inc Expandable intervertebral implant
US9486327B2 (en) 2014-05-15 2016-11-08 Globus Medical, Inc. Standalone interbody implants
US9486325B2 (en) 2013-03-15 2016-11-08 Globus Medical, Inc. Expandable intervertebral implant
US9492289B2 (en) 2013-03-15 2016-11-15 Globus Medical, Inc. Expandable intervertebral implant
US9526630B2 (en) 2011-09-16 2016-12-27 Globus Medical, Inc. Low profile plate
US9539103B2 (en) 2013-03-15 2017-01-10 Globus Medical, Inc. Expandable intervertebral implant
US9539109B2 (en) 2011-09-16 2017-01-10 Globus Medical, Inc. Low profile plate
US9545320B2 (en) 2014-05-15 2017-01-17 Globus Medical, Inc. Standalone interbody implants
US9585765B2 (en) 2013-02-14 2017-03-07 Globus Medical, Inc Devices and methods for correcting vertebral misalignment
US9615936B2 (en) 2009-06-04 2017-04-11 Globus Medical, Inc. Intervertebral fusion implant
US9675465B2 (en) 2014-05-15 2017-06-13 Globus Medical, Inc. Standalone interbody implants
US9681959B2 (en) 2011-09-16 2017-06-20 Globus Medical, Inc. Low profile plate
US9700425B1 (en) 2011-03-20 2017-07-11 Nuvasive, Inc. Vertebral body replacement and insertion methods
US9707092B2 (en) 2013-03-15 2017-07-18 Globus Medical, Inc. Expandable intervertebral implant
US9848994B2 (en) 2011-09-16 2017-12-26 Globus Medical, Inc. Low profile plate
US9895237B2 (en) 2010-04-08 2018-02-20 Globus Medical, Inc. Intervertebral implant
US9943418B2 (en) 2013-03-15 2018-04-17 Globus Medical, Inc. Expandable intervertebral implant
US9968461B2 (en) 2014-05-15 2018-05-15 Globus Medical, Inc. Standalone interbody implants
US10028842B2 (en) 2013-03-15 2018-07-24 Globus Medical, Inc. Expandable intervertebral implant
US10034768B2 (en) * 2015-09-02 2018-07-31 Globus Medical, Inc. Implantable systems, devices and related methods

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2858546B1 (en) * 2003-08-04 2006-04-28 Spine Next Sa Prothese of intervertebral disc
US7780732B2 (en) * 2005-03-16 2010-08-24 Dennis Lee Abernathie Spinal fusion cage and method of use
US9744052B2 (en) 2005-04-12 2017-08-29 Nathan C. Moskowitz Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs
US9848993B2 (en) 2005-04-12 2017-12-26 Nathan C. Moskowitz Zero-profile expandable intervertebral spacer devices for distraction and spinal fusion and a universal tool for their placement and expansion
US7942903B2 (en) 2005-04-12 2011-05-17 Moskowitz Ahmnon D Bi-directional fixating transvertebral body screws and posterior cervical and lumbar interarticulating joint calibrated stapling devices for spinal fusion
US9532821B2 (en) 2005-04-12 2017-01-03 Nathan C. Moskowitz Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs with vertical hemi-bracket screw locking mechanism
US9814601B2 (en) 2005-04-12 2017-11-14 Nathan C. Moskowitz Bi-directional fixating/locking transvertebral body screw/intervertebral cage stand-alone constructs
US20070005064A1 (en) * 2005-06-27 2007-01-04 Sdgi Holdings Intervertebral prosthetic device for spinal stabilization and method of implanting same
US7731752B2 (en) * 2006-07-21 2010-06-08 Warsaw Orthopedic, Inc. Implant with nested members and methods of use
US8057545B2 (en) * 2006-08-25 2011-11-15 Warsaw Orthopedic, Inc. Revision spacer
US20080177387A1 (en) * 2006-11-01 2008-07-24 Warsaw Orthopedic, Inc. Implants and Related Devices for Monitoring Bony Fusion
US8034081B2 (en) 2007-02-06 2011-10-11 CollabComl, LLC Interspinous dynamic stabilization implant and method of implanting
JP2010521242A (en) 2007-03-13 2010-06-24 ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング Adjustable intervertebral implant
US8545566B2 (en) 2008-10-13 2013-10-01 Globus Medical, Inc. Articulating spacer
US8147554B2 (en) 2008-10-13 2012-04-03 Globus Medical, Inc. Intervertebral spacer
US8870957B2 (en) * 2009-03-04 2014-10-28 Amendia, Inc. Implant for mammalian bony segment stabilization
US8740983B1 (en) 2009-11-11 2014-06-03 Nuvasive, Inc. Spinal fusion implants and related methods
US8840668B1 (en) 2009-11-11 2014-09-23 Nuvasive, Inc. Spinal implants, instruments and related methods
EP2547292A4 (en) 2010-03-16 2013-09-18 Pinnacle Spine Group Llc Intervertebral implants and graft delivery systems and methods
US8282683B2 (en) * 2010-04-12 2012-10-09 Globus Medical, Inc. Expandable vertebral implant
WO2012103254A3 (en) * 2011-01-25 2014-04-10 Nuvasive, Inc. Spinal implants for rotationally adjusting vertebrae
DE102011000377A1 (en) * 2011-01-27 2012-08-02 Aesculap Ag Vertebral cage implant has through-hole or recess that is formed along height direction, and is provided with inhomogeneous cross-section along longitudinal direction
US8496689B2 (en) * 2011-02-23 2013-07-30 Farzad Massoudi Spinal implant device with fusion cage and fixation plates and method of implanting
EP2608749B1 (en) * 2011-03-11 2016-08-10 FBC Device Aps Spinal implant
US9913732B2 (en) * 2011-11-02 2018-03-13 Spinesmith Partners, L.P. Interbody fusion device with separable retention component for lateral approach and associated methods
US9380932B1 (en) 2011-11-02 2016-07-05 Pinnacle Spine Group, Llc Retractor devices for minimally invasive access to the spine
US9238319B2 (en) 2013-03-14 2016-01-19 DePuy Synthes Products, Inc. Hybrid intervertebral disc spacer device and method of manufacturing the same
US9968460B2 (en) 2013-03-15 2018-05-15 Medsmart Innovation Inc. Dynamic spinal segment replacement
USD745159S1 (en) 2013-10-10 2015-12-08 Nuvasive, Inc. Intervertebral implant

Citations (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892545A (en) * 1988-07-14 1990-01-09 Ohio Medical Instrument Company, Inc. Vertebral lock
US5192327A (en) * 1991-03-22 1993-03-09 Brantigan John W Surgical prosthetic implant for vertebrae
US5360430A (en) * 1993-07-29 1994-11-01 Lin Chih I Intervertebral locking device
US5397364A (en) * 1993-10-12 1995-03-14 Danek Medical, Inc. Anterior interbody fusion device
US5458641A (en) * 1993-09-08 1995-10-17 Ramirez Jimenez; Juan J. Vertebral body prosthesis
US5916267A (en) * 1997-04-07 1999-06-29 Arthit Sitiso Anterior spinal implant system for vertebral body prosthesis
US6039761A (en) * 1997-02-12 2000-03-21 Li Medical Technologies, Inc. Intervertebral spacer and tool and method for emplacement thereof
US6159211A (en) * 1998-10-22 2000-12-12 Depuy Acromed, Inc. Stackable cage system for corpectomy/vertebrectomy
US20020052656A1 (en) * 2000-02-04 2002-05-02 Michelson Gary Karlin Expandable push-in interbody spinal fusion implant
US6395030B1 (en) * 1998-06-18 2002-05-28 Michigan Technological University Spinal fixation system
US20020077702A1 (en) * 2000-12-19 2002-06-20 Cortek, Inc. Dynamic implanted intervertebral spacer
US6409766B1 (en) * 1998-07-30 2002-06-25 Expanding Concepts, Llc Collapsible and expandable interbody fusion device
US20020091446A1 (en) * 1997-10-27 2002-07-11 Zucherman James F. Interspinous process distraction system and method with positionable wing and method
US6432107B1 (en) * 2000-01-15 2002-08-13 Bret A. Ferree Enhanced surface area spinal fusion devices
US6447544B1 (en) * 1995-06-07 2002-09-10 Gary Karlin Michelson Lordotic interbody spinal fusion implants
US20020128715A1 (en) * 2000-08-08 2002-09-12 Vincent Bryan Implantable joint prosthesis
US6468311B2 (en) * 2001-01-22 2002-10-22 Sdgi Holdings, Inc. Modular interbody fusion implant
US6475219B1 (en) * 2001-06-07 2002-11-05 Alexis P. Shelokov Anterior vertebral protection method and device
US20020169508A1 (en) * 1998-06-18 2002-11-14 Pioneer Laboratories, Inc. Spinal fixation system
US6500205B1 (en) * 2000-04-19 2002-12-31 Gary K. Michelson Expandable threaded arcuate interbody spinal fusion implant with cylindrical configuration during insertion
US20030023312A1 (en) * 2000-08-15 2003-01-30 Thalgott John S. Disc prosthesis
US20030045940A1 (en) * 2001-08-24 2003-03-06 Robert Eberlein Artificial intervertebral disc
US6562074B2 (en) * 2001-10-17 2003-05-13 Medicinelodge, Inc. Adjustable bone fusion implant and method
US20030100950A1 (en) * 2000-03-22 2003-05-29 Olivier Moret Cage-type intervertebral implant
US6579290B1 (en) * 1997-11-29 2003-06-17 Surgicraft Limited Surgical implant and surgical fixing screw
US20030125739A1 (en) * 2001-12-12 2003-07-03 Bagga Charanpreet S. Bioactive spinal implants and method of manufacture thereof
US6613051B1 (en) * 1999-11-17 2003-09-02 The University Of Hong Kong Anterior transpedicular fixation system and method for maintaining a vertebral column
US20030171813A1 (en) * 2002-03-05 2003-09-11 P. Douglas Kiester Method and apparatus for providing an expandable spinal fusion cage
US20040030387A1 (en) * 2002-03-11 2004-02-12 Landry Michael E. Instrumentation and procedure for implanting spinal implant devices
US20040068318A1 (en) * 2002-10-02 2004-04-08 Coates Bradley J. Modular intervertebral prosthesis system
US20040073314A1 (en) * 2002-03-21 2004-04-15 White John L. Vertebral body and disc space replacement devices
US6723126B1 (en) * 2002-11-01 2004-04-20 Sdgi Holdings, Inc. Laterally expandable cage
US20050060034A1 (en) * 2003-09-15 2005-03-17 Sdgi Holdings, Inc. Revisable prosthetic device
US20050060036A1 (en) * 2003-05-21 2005-03-17 Robert Schultz Spinal column implant
US20060058877A1 (en) * 2002-12-06 2006-03-16 Michael Gutlin Intervertebral implant

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1283501C (en) * 1987-02-12 1991-04-30 Thomas P. Hedman Artificial spinal disc
US6039762A (en) * 1995-06-07 2000-03-21 Sdgi Holdings, Inc. Reinforced bone graft substitutes
US6045579A (en) * 1997-05-01 2000-04-04 Spinal Concepts, Inc. Adjustable height fusion device
FR2762778B1 (en) * 1997-05-02 1999-07-16 Stryker France Sa Implant particularly to replace a vertebral body in spine surgery
US6086613A (en) * 1997-12-23 2000-07-11 Depuy Acromed, Inc. Spacer assembly for use in spinal surgeries
US6241769B1 (en) * 1998-05-06 2001-06-05 Cortek, Inc. Implant for spinal fusion
CA2338379A1 (en) * 1998-07-22 2000-02-03 Spinal Dynamics Corporation Threaded cylindrical multidiscoid single or multiple array disc prosthesis
US6749635B1 (en) * 1998-09-04 2004-06-15 Sdgi Holdings, Inc. Peanut spectacle multi discoid thoraco-lumbar disc prosthesis
CA2342633C (en) * 1998-09-04 2007-11-13 Spinal Dynamics Corporation Peanut spectacle multi discoid thoraco-lumbar disc prosthesis
FR2787019B1 (en) * 1998-12-11 2001-03-02 Dimso Sa intervertebral disk prosthesis has mechanical behavior improves
DE60018924D1 (en) * 1999-06-04 2005-04-28 Sdgi Holdings Inc Artificial intervertebral implant
JP2003511202A (en) * 1999-10-21 2003-03-25 エスディージーアイ・ホールディングス・インコーポレーテッド Apparatus and techniques for the rear lateral disc space approach
JP3785301B2 (en) * 2000-02-22 2006-06-14 トヨタ紡織株式会社 Hollow weave air bag
US6767369B2 (en) * 2000-03-22 2004-07-27 Synthes (Usa) Plugs for filling bony defects
US6610093B1 (en) * 2000-07-28 2003-08-26 Perumala Corporation Method and apparatus for stabilizing adjacent vertebrae
DK1409032T3 (en) 2001-05-30 2005-12-19 Tecres Spa Röntgenabsorberende, acrylic-based bone cement and method for manufacturing the same
JP2003038535A (en) * 2001-07-30 2003-02-12 Robert Reed Shokai Co Ltd Prosthetic device for spine
US6808538B2 (en) * 2002-03-15 2004-10-26 Stryker Spine Vertebral body spacer having variable wedged endplates
US6758862B2 (en) * 2002-03-21 2004-07-06 Sdgi Holdings, Inc. Vertebral body and disc space replacement devices
US6726720B2 (en) * 2002-03-27 2004-04-27 Depuy Spine, Inc. Modular disc prosthesis
WO2003090650A1 (en) * 2002-04-25 2003-11-06 Blackstone Medical, Inc. Artificial intervertebral disc
US7018415B1 (en) * 2002-09-23 2006-03-28 Sdgi Holdings, Inc. Expandable spinal fusion device and methods of promoting spinal fusion

Patent Citations (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892545A (en) * 1988-07-14 1990-01-09 Ohio Medical Instrument Company, Inc. Vertebral lock
US5192327A (en) * 1991-03-22 1993-03-09 Brantigan John W Surgical prosthetic implant for vertebrae
US5360430A (en) * 1993-07-29 1994-11-01 Lin Chih I Intervertebral locking device
US5458641A (en) * 1993-09-08 1995-10-17 Ramirez Jimenez; Juan J. Vertebral body prosthesis
US5397364A (en) * 1993-10-12 1995-03-14 Danek Medical, Inc. Anterior interbody fusion device
US6447544B1 (en) * 1995-06-07 2002-09-10 Gary Karlin Michelson Lordotic interbody spinal fusion implants
US6039761A (en) * 1997-02-12 2000-03-21 Li Medical Technologies, Inc. Intervertebral spacer and tool and method for emplacement thereof
US5916267A (en) * 1997-04-07 1999-06-29 Arthit Sitiso Anterior spinal implant system for vertebral body prosthesis
US20020091446A1 (en) * 1997-10-27 2002-07-11 Zucherman James F. Interspinous process distraction system and method with positionable wing and method
US6579290B1 (en) * 1997-11-29 2003-06-17 Surgicraft Limited Surgical implant and surgical fixing screw
US6682561B2 (en) * 1998-06-18 2004-01-27 Pioneer Laboratories, Inc. Spinal fixation system
US6395030B1 (en) * 1998-06-18 2002-05-28 Michigan Technological University Spinal fixation system
US20020169508A1 (en) * 1998-06-18 2002-11-14 Pioneer Laboratories, Inc. Spinal fixation system
US6409766B1 (en) * 1998-07-30 2002-06-25 Expanding Concepts, Llc Collapsible and expandable interbody fusion device
US6159211A (en) * 1998-10-22 2000-12-12 Depuy Acromed, Inc. Stackable cage system for corpectomy/vertebrectomy
US6613051B1 (en) * 1999-11-17 2003-09-02 The University Of Hong Kong Anterior transpedicular fixation system and method for maintaining a vertebral column
US20020128652A1 (en) * 1999-12-03 2002-09-12 Ferree Bret A. Version with markings to show changes made
US6432107B1 (en) * 2000-01-15 2002-08-13 Bret A. Ferree Enhanced surface area spinal fusion devices
US20020052656A1 (en) * 2000-02-04 2002-05-02 Michelson Gary Karlin Expandable push-in interbody spinal fusion implant
US20030100950A1 (en) * 2000-03-22 2003-05-29 Olivier Moret Cage-type intervertebral implant
US6500205B1 (en) * 2000-04-19 2002-12-31 Gary K. Michelson Expandable threaded arcuate interbody spinal fusion implant with cylindrical configuration during insertion
US20020128715A1 (en) * 2000-08-08 2002-09-12 Vincent Bryan Implantable joint prosthesis
US20030023312A1 (en) * 2000-08-15 2003-01-30 Thalgott John S. Disc prosthesis
US20020077702A1 (en) * 2000-12-19 2002-06-20 Cortek, Inc. Dynamic implanted intervertebral spacer
US20030040799A1 (en) * 2001-01-22 2003-02-27 Boyd Lawrence M. Modular interbody fusion implant
US6468311B2 (en) * 2001-01-22 2002-10-22 Sdgi Holdings, Inc. Modular interbody fusion implant
US6475219B1 (en) * 2001-06-07 2002-11-05 Alexis P. Shelokov Anterior vertebral protection method and device
US20030045940A1 (en) * 2001-08-24 2003-03-06 Robert Eberlein Artificial intervertebral disc
US6852129B2 (en) * 2001-10-17 2005-02-08 Movdice Holding, Inc. Adjustable bone fusion implant and method
US6562074B2 (en) * 2001-10-17 2003-05-13 Medicinelodge, Inc. Adjustable bone fusion implant and method
US20030125739A1 (en) * 2001-12-12 2003-07-03 Bagga Charanpreet S. Bioactive spinal implants and method of manufacture thereof
US20030171813A1 (en) * 2002-03-05 2003-09-11 P. Douglas Kiester Method and apparatus for providing an expandable spinal fusion cage
US20040030387A1 (en) * 2002-03-11 2004-02-12 Landry Michael E. Instrumentation and procedure for implanting spinal implant devices
US20040073314A1 (en) * 2002-03-21 2004-04-15 White John L. Vertebral body and disc space replacement devices
US20040068318A1 (en) * 2002-10-02 2004-04-08 Coates Bradley J. Modular intervertebral prosthesis system
US6723126B1 (en) * 2002-11-01 2004-04-20 Sdgi Holdings, Inc. Laterally expandable cage
US20060058877A1 (en) * 2002-12-06 2006-03-16 Michael Gutlin Intervertebral implant
US20050060036A1 (en) * 2003-05-21 2005-03-17 Robert Schultz Spinal column implant
US20050060034A1 (en) * 2003-09-15 2005-03-17 Sdgi Holdings, Inc. Revisable prosthetic device

Cited By (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8888852B2 (en) 2004-01-09 2014-11-18 Hh Spinal Llc Spinal athroplasty device and method
US8372150B2 (en) 2004-01-09 2013-02-12 Warsaw Orthpedic, Inc. Spinal device and method
US20050171608A1 (en) * 2004-01-09 2005-08-04 Sdgi Holdings, Inc. Centrally articulating spinal device and method
US9744053B2 (en) 2004-03-29 2017-08-29 Nuvasive, Inc. Systems and methods for spinal fusion
US8814940B2 (en) * 2004-03-29 2014-08-26 Nuvasive, Inc. Systems and methods for spinal fusion
US8608804B2 (en) * 2004-03-29 2013-12-17 Nuvasive, Inc. Systems and methods for spinal fusion
US9474627B2 (en) 2004-03-29 2016-10-25 Nuvasive, Inc. Systems and methods for spinal fusion
US9180021B2 (en) 2004-03-29 2015-11-10 Nuvasive, Inc. Systems and methods for spinal fusion
US8574301B2 (en) * 2004-03-29 2013-11-05 Nuvasive, Inc. Systems and methods for spinal fusion
US20060178746A1 (en) * 2005-02-10 2006-08-10 Depuy Spine, Inc. Intervertebral prosthetic disc and method for installing using a guidewire
US7690381B2 (en) * 2005-02-10 2010-04-06 Depuy Spine, Inc. Intervertebral prosthetic disc and method for installing using a guidewire
US7875075B2 (en) 2005-09-26 2011-01-25 Warsaw Orthopedic, Inc. Hybrid intervertebral spinal fusion implant
US20070233248A1 (en) * 2005-09-26 2007-10-04 Schwab Frank J Anterior hybrid implant
US20110112643A1 (en) * 2005-09-26 2011-05-12 Schwab Frank J Hybrid Intervertebral Spinal Fusion Implant
US20140257492A1 (en) * 2005-09-26 2014-09-11 Warsaw Orthopedic, Inc. Anterior hybrid implant
US8728166B2 (en) 2005-09-26 2014-05-20 Warsaw Orthopedic, Inc. Hybrid intervertebral spinal fusion implant
US8764832B2 (en) * 2005-09-26 2014-07-01 Warsaw Orhtopedic, Inc. Anterior hybrid implant
US7998212B2 (en) * 2005-09-26 2011-08-16 Warsaw Orthopedic, Inc. Transforaminal hybrid implant
US20070233247A1 (en) * 2005-09-26 2007-10-04 Schwab Frank J Hybrid intervertebral spinal fusion implant
US20070093898A1 (en) * 2005-09-26 2007-04-26 Schwab Frank J Transforaminal hybrid implant
US7988695B2 (en) 2005-12-21 2011-08-02 Theken Spine, Llc Articulated delivery instrument
US7811326B2 (en) 2006-01-30 2010-10-12 Warsaw Orthopedic Inc. Posterior joint replacement device
US20090306715A1 (en) * 2006-02-01 2009-12-10 Jackson Benjamin L Interspinous process spacer
US8500778B2 (en) * 2006-02-01 2013-08-06 DePuy Synthes Products, LLC Interspinous process spacer
US20140100663A1 (en) * 2006-02-27 2014-04-10 DePuy Synthes Products, LLC Intervertebral implant with fixation geometry
US7976549B2 (en) 2006-03-23 2011-07-12 Theken Spine, Llc Instruments for delivering spinal implants
US20070239278A1 (en) * 2006-04-06 2007-10-11 Sdgi Holdings, Inc. Intervertebral prosthetic devices and methods
US8506636B2 (en) 2006-09-08 2013-08-13 Theken Spine, Llc Offset radius lordosis
WO2008065450A1 (en) 2006-11-29 2008-06-05 Surgicraft Limited Orthopaedic implants and prostheses
US20080140204A1 (en) * 2006-12-07 2008-06-12 Warsaw Orthopedic, Inc. Vertebral Implant Systems and Methods of Use
US9186261B2 (en) 2007-03-07 2015-11-17 Nuvasive, Inc. System and methods for spinal fusion
US9486329B2 (en) 2007-03-07 2016-11-08 Nuvasive, Inc. System and methods for spinal fusion
US9918852B2 (en) 2007-03-07 2018-03-20 Nuvasive, Inc. System and methods for spinal fusion
US8864832B2 (en) 2007-06-20 2014-10-21 Hh Spinal Llc Posterior total joint replacement
US9168152B2 (en) 2008-02-29 2015-10-27 Nuvasive, Inc. Implants and methods for spinal fusion
US9907672B1 (en) 2008-02-29 2018-03-06 Nuvasive, Inc. Implants and methods for spinal fusion
US9833333B2 (en) 2008-09-02 2017-12-05 Globus Medical, Inc. Intervertebral fusion implant
US9675467B2 (en) 2008-09-02 2017-06-13 Globus Medical, Inc. Intervertebral fusion implant
US9364343B2 (en) 2008-09-02 2016-06-14 Globus Medical, Inc. Intervertebral fusion implant
US9358127B2 (en) 2008-09-02 2016-06-07 Globus Medical, Inc. Intervertebral fusion implant
USD797934S1 (en) 2009-03-02 2017-09-19 Nuvasive, Inc. Spinal fusion implant
USD754346S1 (en) 2009-03-02 2016-04-19 Nuvasive, Inc. Spinal fusion implant
US9615936B2 (en) 2009-06-04 2017-04-11 Globus Medical, Inc. Intervertebral fusion implant
US9211195B2 (en) 2009-10-13 2015-12-15 Nicholas Poulos Expandable interbody implant and method
US20110087329A1 (en) * 2009-10-13 2011-04-14 Nicholas Poulos Lumbar implant
US9180017B2 (en) * 2009-10-13 2015-11-10 Nicholas Poulos Lumbar implant
US20130178939A1 (en) * 2009-10-13 2013-07-11 Nicholas Poulos Expandable interbody implant and method
US8906099B2 (en) * 2009-10-13 2014-12-09 Nicholas Poulos Expandable interbody implant and method
US9408718B2 (en) 2009-12-31 2016-08-09 Rhausler, Inc. Inter-vertebral implant with angled plate
US8945226B2 (en) * 2009-12-31 2015-02-03 Rhausler Vertebral spacer
US20110160860A1 (en) * 2009-12-31 2011-06-30 Rhausler, Inc. Cervical spacer
US9895237B2 (en) 2010-04-08 2018-02-20 Globus Medical, Inc. Intervertebral implant
US9700425B1 (en) 2011-03-20 2017-07-11 Nuvasive, Inc. Vertebral body replacement and insertion methods
US9848994B2 (en) 2011-09-16 2017-12-26 Globus Medical, Inc. Low profile plate
US9526630B2 (en) 2011-09-16 2016-12-27 Globus Medical, Inc. Low profile plate
US9681959B2 (en) 2011-09-16 2017-06-20 Globus Medical, Inc. Low profile plate
US9539109B2 (en) 2011-09-16 2017-01-10 Globus Medical, Inc. Low profile plate
US9198765B1 (en) 2011-10-31 2015-12-01 Nuvasive, Inc. Expandable spinal fusion implants and related methods
US9655744B1 (en) 2011-10-31 2017-05-23 Nuvasive, Inc. Expandable spinal fusion implants and related methods
US9326861B2 (en) 2012-08-03 2016-05-03 Globus Medical, Inc. Stabilizing joints
US9585765B2 (en) 2013-02-14 2017-03-07 Globus Medical, Inc Devices and methods for correcting vertebral misalignment
US9364340B2 (en) 2013-03-05 2016-06-14 Globus Medical, Inc. Low profile plate
US10028842B2 (en) 2013-03-15 2018-07-24 Globus Medical, Inc. Expandable intervertebral implant
US9539103B2 (en) 2013-03-15 2017-01-10 Globus Medical, Inc. Expandable intervertebral implant
US9492289B2 (en) 2013-03-15 2016-11-15 Globus Medical, Inc. Expandable intervertebral implant
US9707092B2 (en) 2013-03-15 2017-07-18 Globus Medical, Inc. Expandable intervertebral implant
US9486325B2 (en) 2013-03-15 2016-11-08 Globus Medical, Inc. Expandable intervertebral implant
US9943418B2 (en) 2013-03-15 2018-04-17 Globus Medical, Inc. Expandable intervertebral implant
US9833336B2 (en) 2013-03-15 2017-12-05 Globus Medical, Inc. Expandable intervertebral implant
US9480579B2 (en) 2013-03-15 2016-11-01 Globus Medical, Inc. Expandable intervertebral implant
US9474622B2 (en) 2013-03-15 2016-10-25 Globus Medical, Inc Expandable intervertebral implant
US9456906B2 (en) 2013-03-15 2016-10-04 Globus Medical, Inc. Expandable intervertebral implant
US10034773B2 (en) 2013-03-15 2018-07-31 Globus Medical, Inc. Expandable intervertebral implant
US9211193B2 (en) 2013-08-30 2015-12-15 Aesculap Implant Systems, Llc Prosthesis, system and method
US9486327B2 (en) 2014-05-15 2016-11-08 Globus Medical, Inc. Standalone interbody implants
US9968461B2 (en) 2014-05-15 2018-05-15 Globus Medical, Inc. Standalone interbody implants
US9980826B2 (en) 2014-05-15 2018-05-29 Globus Medical, Inc. Standalone interbody implants
US9545320B2 (en) 2014-05-15 2017-01-17 Globus Medical, Inc. Standalone interbody implants
US9675465B2 (en) 2014-05-15 2017-06-13 Globus Medical, Inc. Standalone interbody implants
US10034768B2 (en) * 2015-09-02 2018-07-31 Globus Medical, Inc. Implantable systems, devices and related methods

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US7776093B2 (en) 2010-08-17 grant
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WO2005041816A2 (en) 2005-05-12 application
WO2005041816A3 (en) 2006-05-11 application

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