US20050049708A1 - Devices and methods for the treatment of spinal disorders - Google Patents

Devices and methods for the treatment of spinal disorders Download PDF

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US20050049708A1
US20050049708A1 US10967042 US96704204A US2005049708A1 US 20050049708 A1 US20050049708 A1 US 20050049708A1 US 10967042 US10967042 US 10967042 US 96704204 A US96704204 A US 96704204A US 2005049708 A1 US2005049708 A1 US 2005049708A1
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member
bias
disc
vertebrae
implantable
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US10967042
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Robert Atkinson
Peter Keith
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Anulex Technologies Inc
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Anulex Technologies Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7002Longitudinal elements, e.g. rods
    • A61B17/7019Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other
    • A61B17/7025Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other with a sliding joint
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7002Longitudinal elements, e.g. rods
    • A61B17/7019Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other
    • A61B17/7026Longitudinal elements having flexible parts, or parts connected together, such that after implantation the elements can move relative to each other with a part that is flexible due to its form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7062Devices acting on, attached to, or simulating the effect of, vertebral processes, vertebral facets or ribs ; Tools for such devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7001Screws or hooks combined with longitudinal elements which do not contact vertebrae
    • A61B17/7002Longitudinal elements, e.g. rods
    • A61B17/7011Longitudinal element being non-straight, e.g. curved, angled or branched
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00535Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated
    • A61B2017/00557Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated inflatable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • A61F2002/4435Support means or repair of the natural disc wall, i.e. annulus, e.g. using plates, membranes or meshes

Abstract

Devices and methods for treating a damaged intervertebral disc to reduce or eliminate associated back pain. Dynamic bias devices and reinforcement devices are disclosed, which may be used individually or in combination, to eliminate nerve impingement associated with the damaged disc, and/or to reinforce the damaged disc, while permitting relative movement of the vertebrae adjacent the damaged disc.

Description

    FIELD OF THE INVENTION
  • The present invention generally relates to spinal implants. Specifically, the present invention relates to implantable devices and methods for the treatment of spinal disorders associated with the intervertebral disc.
  • BACKGROUND OF THE INVENTION
  • Back pain is one of the most common and often debilitating conditions affecting millions of people in all walks of life. Today, it is estimated that over ten million people in the United States alone suffer from persistent back pain. Approximately half of those suffering from persistent back pain are afflicted with chronic disabling pain, which seriously compromises a person's quality of life and is the second most common cause of worker absenteeism. Further, the cost of treating chronic back pain is very high, even though the majority of sufferers do not receive treatment due to health risks, limited treatment options and inadequate therapeutic results. Thus, chronic back pain has a significantly adverse effect on a person's quality of life, on industrial productivity, and on heath care expenditures.
  • Some forms of back pain are not chronic and may be simply treated by rest, posture adjustments and painkillers. For example, some forms of lower back pain (LBP) are very common and may be caused by unusual exertion or injury. Unusual exertion such has heavy lifting or strenuous exercise may result in back strain such as a pulled muscle, sprained muscle, sprained ligament, muscle spasm, or a combination thereof. An injury caused by falling down or a blow to the back may cause bruising. These forms of back pain are typically non-chronic and may be self-treated and cured in a few days or weeks.
  • Other types of non-chronic back pain may be treated by improvements in physical condition, posture and/or work conditions. For example, being pregnant, obese or otherwise significantly overweight may cause LBP. A mattress that does not provide adequate support may cause back pain in the morning. Working in an environment lacking good ergonomic design may also cause back pain. In these instances, the back pain may be cured by eliminating the culprit cause. Whether it is excess body weight, a bad mattress, or a bad office chair, these forms of back pain are readily treated.
  • However, some forms of back pain are chronic and are the result of spinal disorders which are not readily treated. Such spinal disorders may cause severe back pain, the origin of which may or may not be certain. A prevalent clinical theory is that pain arises from physical impingement of the nerve roots or the spinal cord. Such nerve impingement may have of a number of different causes, but generally results from either a disc protrusion or from narrowing of the intervertebral foramina which surround the nerve roots. Another clinical theory is that damage to the disc, either from injury, degradation or otherwise, causes physical impingement of the disc nerves, which are primarily disposed about the periphery of the annulus, but may grow into fissures of a damaged disc.
  • Disc protrusions may be caused by a physical injury to the disc or by natural degradation of the disc such as by degenerative disc disease (DDD). Physical injury may cause damage to the annulus fibrosus which allows a portion of the disc, such as the nucleus pulposus, to protrude from the normal disc space. DDD may cause the entire disc to degenerate to such a degree that the annulus fibrosus bulges outward, delaminates or otherwise separates such that a portion of the disc protrudes from the normal disc space. In either case, the disc protrusion may impinge on a spinal nerve root causing severe pain. Impingement on the nerve root may also be caused by conditions unrelated to the disc such as by a spinal tumor or spinal stenosis (abnormal bone growth), but disc protrusions are the most common cause. Depending on the cause and nature of the disc protrusion, the condition may be referred to as a disc stenosis, a disc bulge, a herniated disc, a slipped disc, a prolapsed disc or, if the protrusion separates from the disc, a sequestered disc.
  • Nerve root impingement most often occurs in the lumbar region of the spinal column since the lumbar discs bear significant vertical loads relative to discs in other regions of the spine. In addition, disc protrusions in the lumbar region typically occur posteriorly because the annulus fibrosus is thinner on the posterior side than on the anterior side and because normal posture places more compression on the posterior side. Posterior protrusions are particularly problematic since the nerve roots are posteriorly positioned relative to the intervertebral discs. When a posterior disc protrusion presses against a nerve root, the pain is often severe and radiating, and may be aggravated by such subtle movements as coughing, bending over, or remaining in a sitting position for an extended period of time.
  • A common treatment for disc protrusion is discectomy, which is a procedure wherein the protruding portion of the disc is surgically removed. However, discectomy procedures have an inherent risk since the portion of the disc to be removed is immediately adjacent the nerve root and any damage to the nerve root is clearly undesirable. Furthermore, discectomy procedures are not always successful long term because scar tissue may form and/or additional disc material may subsequently protrude from the disc space as the disc deteriorates further. The recurrence of a disc protrusion may necessitate a repeat discectomy procedure, along with its inherent clinical risks and less than perfect long term success rate. Thus, a discectomy procedure, at least as a stand-alone procedure, is clearly not an optimal solution.
  • Discectomy is also not a viable solution for DDD when no disc protrusion is involved. As mentioned above, DDD causes the entire disc to degenerate, narrowing of the intervertebral space, and shifting of the load to the facet joints. If the facet joints carry a substantial load, the joints may degrade over time and be a different cause of back pain. Furthermore, the narrowed disc space can result in the intervertebral foramina surrounding the nerve roots to directly impinge on one or more nerve roots. Such nerve impingement is very painful and cannot be corrected by a discectomy procedure.
  • As a result, spinal fusion, particularly with the assistance of interbody fusion cages, has become a preferred secondary procedure, and in some instances, a preferred primary procedure. Spinal fusion involves permanently fusing or fixing adjacent vertebrae. Hardware in the form of bars, plates, screws and cages may be utilized in combination with bone graft material to fuse adjacent vertebrae. Spinal fusion may be performed as a stand-alone procedure or may be performed in combination with a discectomy procedure. By placing the adjacent vertebrae in their nominal position and fixing them in place, relative movement therebetween may be significantly reduced and the disc space may be restored to its normal condition. Thus, theoretically, aggravation caused by relative movement between adjacent vertebrae (and thus impingement on the nerve root by a disc protrusion and/or impingement from bone may be reduced if not eliminated.
  • However, the success rate of spinal fusion procedures is certainly less than perfect for a number of different reasons, none of which are well understood. In addition, even if spinal fusion procedures are initially successful, they may cause accelerated degeneration of adjacent discs since the adjacent discs must accommodate a greater degree of motion. The degeneration of adjacent discs simply leads to the same problem at a different anatomical location, which is clearly not an optimal solution. Furthermore, spinal fusion procedures are invasive to the disc, risk nerve damage and, depending on the procedural approach, either technically complicated (endoscopic anterior approach), invasive to the bowel (surgical anterior approach), or invasive to the musculature of the back (surgical posterior approach).
  • Another procedure that has been less than clinically successful is total disc replacement with a prosthetic disc. This procedure is also very invasive to the disc and, depending on the procedural approach, either invasive to the bowel (surgical anterior approach) or invasive to the musculature of the back (surgical posterior approach). In addition, the procedure may actually complicate matters by creating instability in the spine, and the long term mechanical reliability of prosthetic discs has yet to be demonstrated.
  • Many other medical procedures have been proposed to solve the problems associated with disc protrusions. However, many of the proposed procedures have not been clinically proven and some of the allegedly beneficial procedures have controversial clinical data. From the foregoing, it should be apparent that there is a substantial need for improvements in the treatment of spinal disorders, particularly in the treatment of nerve impingement as the result of damage to the disc, whether by injury, degradation, or the like.
  • SUMMARY OF THE INVENTION
  • The present invention addresses this need by providing improved devices and methods for the treatment of spinal disorders. As used herein, the term spinal disorder generally refers to a degradation in spinal condition as the result of injury, aging or the like, as opposed to a spinal deformity resulting from growth defects. The improved devices and methods of the present invention specifically address nerve impingement as the result of damage to the disc, particularly in the lumbar region, but may have other significant applications not specifically mentioned herein. For purposes of illustration only, and without limitation, the present invention is discussed in detail with reference to the treatment of damaged discs in the lumbar region of the adult human spinal column.
  • As will become apparent from the following description, the improved devices and methods of the present invention reduce if not eliminate back pain while maintaining near normal anatomical motion. Specifically, the present invention provides dynamic bias devices and reinforcement devices, which may be used individually or in combination, to eliminate nerve impingement associated with a damaged disc, and/or to reinforce a damaged disc, while permitting relative movement of the vertebrae adjacent the damaged disc. The devices of the present invention are particularly well suited for minimally invasive methods of implantation.
  • The dynamic bias devices of the present invention basically apply a bias force to adjacent vertebrae on either side of a damaged disc, while permitting relative movement of the vertebrae. By applying a bias force, disc height may be restored, thereby reducing nerve impingement. Specifically, by restoring disc height, the dynamic bias devices of the present invention: retract disc protrusions into the normal disc space thereby reducing nerve impingement by the protrusions; reduce the load carried by the facet joints thereby eliminating nerve impingement originating at the joint; restore intervertebral spacing thereby eliminating nerve impingement by the intervertebral foramina; and reduce pressure on portions of the annulus thereby alleviating nerve impingement in disc fissures.
  • The reinforcement devices of the present invention basically reinforce a damaged disc, restore disc height and/or bear some or all of the load normally carried by a healthy disc, thereby reducing nerve impingement. Some embodiments of the reinforcement members of the present invention have a relatively small profile when implanted, but are very rigid, and thus serve to reinforce the disc, particularly the annulus. By reinforcing the disc, and particularly the annulus, disc protrusions may reduced or prevented, thereby eliminating nerve impingement by the protrusions. Other embodiments have a relatively large profile when implanted, and thus serve to increase disc height and/or to bear load. By increasing disc height, the advantages discussed previously may be obtained. By bearing some of the load normally carried by a healthy disc, the load may be redistributed as needed, such as when a dynamic bias device is used.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIGS. 1A and 1B illustrate left lateral and posterior views, respectively, of a portion of the adult human vertebral (spinal) column;
  • FIG. 2A illustrates a left lateral view of an intervertebral disc disposed between adjacent vertebrae, wherein the disc is partially protruding from the normal disc space and the disc height is reduced;
  • FIG. 2B illustrates a left lateral view of an intervertebral disc disposed between adjacent vertebrae as in FIG. 2A, wherein dynamic bias devices and reinforcement devices of the present invention, which are illustrated schematically, restore normal disc height and eliminate the disc protrusion;
  • FIGS. 3A-3C schematically illustrate a dynamic bias device 100 in accordance with the present invention;
  • FIGS. 4A-4B schematically illustrate left lateral and posterior views, respectively, of dynamic bias devices of the present invention mounted to adjacent vertebrae equidistant from the median plane;
  • FIGS. 5A-5B schematically illustrate left lateral and posterior views, respectively, of a dynamic bias device of the present invention mounted to adjacent vertebrae in the median plane;
  • FIGS. 6A-6B illustrate end and exploded views, respectively, of a bushing in accordance with a first embodiment of the present invention;
  • FIG. 6C illustrates a posterior view of the bushing shown in FIGS. 6A-6B mounted to a spinous process;
  • FIG. 6D illustrates a posterior view of the spinous process shown in FIG. 6C, detailing the counter-bore;
  • FIGS. 7A-7B illustrate end and exploded views, respectively, of a bushing in accordance with a second embodiment of the present invention;
  • FIGS. 8A-8B illustrate end and exploded views, respectively, of a bushing in accordance with a third embodiment of the present invention;
  • FIGS. 9A-9B illustrate end and exploded views, respectively, of a bushing in accordance with a fourth embodiment of the present invention;
  • FIG. 10A illustrates a side view of a dynamic bias device in accordance with a first embodiment of the present invention;
  • FIG. 10B illustrates a side view of the dynamic bias device shown in FIG. 10A subjected to a compression load;
  • FIG. 10C illustrates a cross-sectional view of the dynamic bias device shown in FIG. 10A;
  • FIG. 11A illustrates a cross-sectional view of a dynamic bias device in accordance with a second embodiment of the present invention;
  • FIG. 11B illustrates a cross-sectional view of a dynamic bias device in accordance with a third embodiment of the present invention;
  • FIGS. 12A-12B illustrate rear and side views, respectively, of a dynamic bias device in accordance with a fourth embodiment of the present invention;
  • FIG. 12C illustrates the dynamic bias device shown in FIGS. 12A-12B subjected to a compression load;
  • FIG. 13A illustrates a side view of a dynamic bias device in accordance with a fifth embodiment of the present invention;
  • FIG. 13B illustrates a side or rear view of a dynamic bias device in accordance with a sixth embodiment of the present invention;
  • FIG. 13C illustrates a rear view of a dynamic bias device in accordance with a seventh embodiment of the present invention;
  • FIGS. 14A-14D illustrate tools of the present invention for implanting the reinforcement members;
  • FIGS. 15A-15J illustrate steps for implanting a self-expanding reinforcement member;
  • FIGS. 15K-15L illustrate steps for implanting an inflatable reinforcement member;
  • FIGS. 15M-1SR illustrate steps for implanting reinforcement bars; AND
  • FIG. 16 illustrates a bias force v. displacement curve for the dynamic bias device.
  • DETAILED DESCRIPTION
  • The following detailed description should be read with reference to the drawings in which similar elements in different drawings are numbered the same. The drawings, which are not necessarily to scale, depict illustrative embodiments and are not intended to limit the scope of the invention.
  • With reference to FIGS. 1A and 1B, the lower portion of an adult human vertebral column 10 is illustrated in left lateral and posterior views, respectively. The upper portion of the vertebral column 10 includes the thoracic region and the cervical region, which are not shown for purposes of simplified illustration only. The lower portion of the vertebral column 10 includes the lumbar region 12, the sacrum 14 and the coccyx 16. The sacrum 14 and the coccyx 16 are sometimes collectively referred to as the pelvic curvature.
  • The vertebral column 10 includes an axis of curvature 60 which generally forms a double-S shape when viewed laterally. The vertebral column 10 also includes a median plane 70 which is a sagittal plane bisecting the vertebral column 10 into symmetrical left lateral and right lateral portions. In posterior views, the median plane 70 appears as a line.
  • The lumbar region 12 of the vertebral column 10 includes five (5) vertebrae 20 (labeled L1, L2, L3, L4 and L5) separated by intervertebral discs 50. The sacrum 14, which includes five (5) fused vertebrae 30 (superior vertebra 30 labeled S1), is separated by a single disc 50 from the coccyx 16, which includes four (4) fused vertebrae 40. Although not labeled, the intervertebral discs 50 may be referenced by their respective adjacent vertebrae. For example, the disc 50 between the L4 and L5 lumbar vertebrae 20 may be referred to as the L4L5 disc. Similarly, the disc 50 between the L5 lumbar vertebra 20 and the S1 sacral vertebra 30 may be referred to as the L5S1 disc.
  • Although each vertebra 20/30/40 is a unique and irregular bone structure, the vertebrae 20 of the lumbar region 12 (in addition to the thoracic and cervical regions) have common structures. Each vertebra 20 of the lumbar region 12 generally includes a body portion 21 and a vertebral arch portion 22/23 which encloses the vertebral foramen (not visible) in which the spinal cord is disposed. The vertebral arch 22/23 includes two pedicles 22 and two laminae 23. A spinous process 24 extends posteriorly from the juncture of the two laminae 23, and two transverse processes 25 extend laterally from each lamina 23. Four articular processes 26/27 extend inferiorly 26 and superiorly 27 from the laminae 23. The inferior articular process 26 rests in the superior articular process 27 of the adjacent vertebra to form a facet joint 28.
  • The five (5) vertebrae 30 of the sacrum 14 are fused together to form a single rigid structure. The sacrum 14 includes a median sacral crest 31 which roughly corresponds to the spinous processes of the vertebrae 30, and two intermediate sacral crests 32 which roughly correspond to the articular processes of the vertebrae 30. The sacral laminae 33 are disposed between the median 31 and intermediate 32 sacral crests. Two lateral sacral crests 34 are disposed on either side of the sacral foraminae 35. The sacrum 14 also includes a pair of sacral wings 36 which define auricular surfaces 39. The superior (S1) sacral vertebra 30 includes two superior articular processes 37 which engage the inferior articular processes 26 of the L5 lumber vertebra 20 to form a facet joint, and the base 38 of the superior sacral vertebra S1 is joined to the L5S1 disc 50.
  • Each intervertebral disc 50 includes an annulus fibrosus 52 surrounding a nucleus pulposus 54, which are more clearly visible in FIG. 15A. The posterior annulus 52 is generally thinner than the anterior annulus 52, which may account for the higher incidence of posterior disc protrusions. As used herein, a disc protrusion generically refers to any portion of the disc that protrudes from the normal disc space. Common clinical conditions that may be characterized as a disc protrusion include a disc stenosis, a disc bulge, a herniated or sequestered disc, a slipped disc, and a prolapsed disc. Generally, a disc protrusion results in a decrease in disc height proportional to the volume of the protrusion. A degenerative disc may sometimes only involve the loss of disc height, and may or may not involve any significant protrusion. However, both degenerative discs and a disc protrusions usually involve some loss in disc height.
  • A common theory is that each intervertebral disc 50 forms one support point and the facet joints form two support points of what may be characterized as a three point support structure between adjacent vertebrae. However, in the lumbar region 12, the facet joints 28 are substantially vertical, leaving the disc 50 to carry the vast majority of the load. As between the annulus fibrosus 52 and the nucleus pulposus 54 of the disc 50, it is commonly believed that the nucleus 54 bears the majority of the load. This belief is based on the theory that the disc 50 behaves much like a balloon or tire, wherein the annulus 22 merely serves to contain the pressurized nucleus 54, and the nucleus 54 bears all the load.
  • However, this theory is questionable since the annulus fibrosus 52 comprises 60% of the total disc 50 cross-section, and the nucleus pulposus 54 only comprises 40% of the total disc 50 cross-section. In addition, the annulus fibrosus 52 is made of 40-60% organized collagen in the form of a laminated structure, whereas the nucleus pulposus 54 is made of 18-30% collagen in the form of a relatively homogenous gel. It seems a more plausible theory is that the annulus fibrosus 52 is the primary load bearing portion of the disc 50.
  • With reference to FIG. 2A, a left lateral view of an intervertebral disc 50 disposed between adjacent vertebrae 20 S (superior) and 20 I (inferior) is illustrated, wherein the disc 50 is partially protruding 56 from the normal disc space and the disc height is reduced. Although the disc 50 is shown to include a protrusion 56, the reduction in disc height may or may not be accompanied with a protrusion 56 as discussed previously. For example, if the disc 50 is degenerated, the disc height may be reduced with or without a corresponding protrusion 56.
  • It should be understood that the vertebrae shown in FIGS. 2A and 2B generically refer to any two adjacent vertebrae or any series of adjacent vertebrae, and that lumbar vertebrae 20 S and 20 I are specifically shown for purposes of illustration only. This generic method of illustrating vertebrae also applies to the remainder of the Figures.
  • With reference to FIG. 2B, a left lateral view of the intervertebral disc 50 disposed between adjacent vertebrae 20 S and 20 I is illustrated as in FIG. 2A. However, in this Figure, devices 100 and 200 of the present invention, which are illustrated schematically, eliminate the disc protrusion 56 and restore normal disc height. Specifically, one or more dynamic bias devices 100 and one or more reinforcement members 200 are utilized, either in combination or individually.
  • The dynamic bias device 100 restores disc height and, by conservation of disc volume, retracts the protrusion into the normal disc space thereby reducing nerve impingement by the protrusion. Restoring disc height also reduces the load carried by the facet joints thereby eliminating nerve impingement originating at the joint, restores intervertebral spacing thereby eliminating nerve impingement by the intervertebral foramina, and reduces pressure on portions of the annulus thereby alleviating nerve impingement in disc fissures.
  • The dynamic bias device 100 basically applies a bias force to the adjacent vertebrae 20 S and 20 I to which it is connected, but allows relative movement of the vertebrae 20 S and 20 I. The dynamic bias device 100 is conceptually similar to a spring attached to the adjacent vertebrae 20 S and 20 I. The dynamic bias device 100 applies a bias force (usually repulsive) between the vertebrae 20 S and 20 I when the disc height is normal or less than normal. The bias force is preferably set such that the disc height is normal with normal posture and loading, and increases with posterior flexure and/or added vertical load. The details of the design and use of the dynamic bias device 100 will be discussed in greater detail hereinafter, particularly with reference to FIGS. 3A-3C, 4A-4B, 5A-5B, 10A-10C, 11A-11B, 12A-12C, and 13A-13C.
  • Because most protrusions 56 are posterior, the dynamic bias device 100 is preferably mounted posterior to the axis of curvature 60. Locating the dynamic bias device 100 posterior to the axis of curvature 60 shifts the load carried by the disc 50 from the posterior portion of the disc to the anterior portion of the disc 50. Locating the dynamic bias device 100 posterior to the axis of curvature 60 also reduces the load carried by the facet joints. Preferably, the dynamic bias device 100 applies a substantially vertical bias force, with the direction independent of displacement.
  • Because more load will be shifted to the anterior portion of the disc 50 with a posterior mounted dynamic bias device 100, reinforcement members 200 may be placed in the anterior annulus 52, to effectively bolster the anterior portion of the disc. The reinforcement members 200 may be used to reinforce the disc, restore disc height and/or bear the load normally carried by annulus. The reinforcement members 200 are relatively rigid and thus serve to reinforce the disc 50 where inserted. In addition, the reinforcement members 200 may have a relatively large profile when implanted and thus increase disc height. The reinforcement members 200 are particularly beneficial if the disc 50 is degenerated, or if the disc 50 will likely become degenerated with the change in load distribution. The details of the design and use of the reinforcement members 200 will be discussed in greater detail hereinafter, particularly with reference to FIGS. 14A-14D and 15A-15R.
  • As mentioned previously, one or more dynamic bias devices 100 and one or more reinforcement members 200 may be utilized, either alone or in combination. Specifically: one or more dynamic bias devices 100 may be used alone; one or more spacer devices 200 may be used alone; and one or more dynamic bias devices 100 and one or more reinforcement members 200 may be used in combination. If a combination of devices 100/200 is used, it is believed that the use of one or more posterior dynamic bias devices 100 in combination with one or more anterior reinforcement members 200 is most effective in treating posterior protrusions 56, facet joint degradation, and nerve impingement by intervertebral foraminae, which are believed to be the most common culprits of chronic LBP.
  • As an alternative to the arrangement shown in FIG. 2B, two or more dynamic bias devices 100 may be attached to the vertebrae on opposite sides of vertebrae 20 S and 20 I. Specifically, one or more dynamic bias devices 100 is connected to vertebra 20 S and the vertebra immediately superior to vertebra 20 S, and one or more dynamic bias devices 100 is connected to vertebra 20 I and the vertebra immediately inferior to vertebra 201. With this arrangement, the dynamic bias devices 100 are primarily applying a traction force to effectively pull vertebrae 20 S and 20 I apart, thereby eliminating the disc protrusion 56 and restoring normal disc height.
  • With reference to FIGS. 3A-3C, the dynamic bias device 100 is schematically illustrated under conditions of no-load, compression load (LC), and traction load (LT), respectively. The dynamic bias device 100 includes a pair of attachment members 102, a bias member 104, and a housing 106. Attachment members 102 facilitate attachment of the dynamic bias device 100 to vertebrae 20 S and 20 I, as shown in FIG. 2B. Bias member 104 functions to apply a bias force between the attachment members 102. Housing 106 functions to separate the moving portions of dynamic bias device 100 from the surrounding muscle, ligaments and other tissue when the dynamic bias device 100 is implanted.
  • Attachment members 102 may comprise a wide variety of mechanical connection designs, and may incorporate into their design, or be used in combination with, other machine elements not specifically mentioned herein. For purposes of illustration only, the each attachment member 102 is shown as loop which may be connected to the vertebrae by fasteners and bushings, specific examples of which are described in detail with reference to FIGS. 6A-6D, 7A-7B, 8A-8B and 9A-9B. These specific examples are provided by way of example, not limitation. Those skilled in the art will recognize that the attachment members 102 may comprise or include screws, rivets, spikes, keys, pins, cotters, splines, couplings, bushings, washers, and the like, without departing from the scope or spirit of the present invention.
  • The primary function of the attachment members 102 is to fixedly secure the ends of the bias member 104 to the vertebrae 20 S and 20 I. Preferably, the attachment members 102 are secured to the vertebrae 20 S and 20 I such that translational movement is minimized or eliminated, and such that rotational movement is permitted between each attachment member 102 and each vertebrae 20 S and 20 I. Providing attachment members 102 with these functional attributes permits the dynamic bias device 100 to effectively transmit a bias force to each vertebrae 20 S and 20 I, allow relative movement therebetween, and minimize stress on the vertebrae 20 S and 20 I at the attachment points.
  • Bias member 104 functions to apply a bias force, either attraction or repulsion, between the attachment members 102. The bias force generally increases or decreases with displacement of the ends of the bias member 104, as with a conventional spring. In addition, the bias force may increase or decrease with the time derivative of displacement (i.e., velocity) of the ends of the bias member 104, as with a conventional damper or shock absorber. As shown in FIG. 3B, the bias member 104 compresses in response to a compression load (LC), thereby increasing or decreasing the bias force. Similarly, as shown in FIG. 3C, the bias member 104 extends in response to a traction load (LT), thereby increasing or decreasing the bias force.
  • If the dynamic bias devices 100 are attached to vertebrae 20 S and 20 I (compression embodiment), as shown in FIG. 2B, the bias force of the bias member 104 increases in response to a compression load (LC), and decreases in response to a traction load (LT). In addition, the bias member 104 normally operates in compression. Preferably, the bias force of the bias member 104 is adjusted such that the disc is restored to a more normal height when the dynamic bias device 100 is implanted. Because the disc height is usually initially less than normal, the dynamic bias device 100 is attached to the vertebrae with the bias member 104 preloaded in compression or with the vertebrae 20 S and 20 I in traction or otherwise spread apart. In this manner, for a given posture, the disc height will be larger following implantation of the dynamic bias device 100 than prior to implantation.
  • If the dynamic bias devices 100 are attached to the vertebrae on opposite sides of vertebrae 20 S and 20 I (traction embodiment), as discussed as an alternative to the arrangement shown in FIG. 2B, the bias force of the bias member 104 decreases in response to a compression load (LC), and increases in response to a traction load (LT). With this latter arrangement, the bias member 104 normally operates in tension. Because the bias member 104 normally operates in tension with this arrangement, the bias member 104 may simply comprise a member that is rigid or semi-rigid in tension, such as a cable. Also with this arrangement, the bias force of the bias member 104 is adjusted such that the disc is restored to a more normal height when the dynamic bias device 100 is implanted. Further with this arrangement, because the disc height is usually initially less than normal, the dynamic bias device 100 is attached to the vertebrae with the bias member 104 preloaded in tension or with the vertebrae 20 S and 20 I in traction or otherwise spread apart.
  • With either arrangement, the dynamic bias device 100 preferably operates with substantially linear displacement substantially parallel to the axis of curvature 60. However, the amount of displacement will be evenly shared between the dynamic bias devices 100 in the traction embodiment, whereas the compression embodiment requires the full displacement to be assumed by each dynamic bias device 100. The following ranges of displacement are given with reference to the compression embodiment. When mounted near the posterior portion of adjacent spinous processes, the dynamic bias device 100 may have a total (i.e., maximum) displacement preferably in the range of 1.0 to 3.0 cm to accommodate full posterior to anterior flexure in the L5-S1 region, 0.5 to 1.5 cm to accommodate full posterior to anterior flexure in the L4-L5 region, and 0.25 to 1.0 cm to accommodate full posterior to anterior flexure in the L1-L4 region.
  • Within these ranges of displacement, it is preferable that bias member 104 operate within its elastic limit, as dictated by the chosen material and geometry of the bias member 104. In addition, because the bias member preferably should be able to withstand 1.0 to 10 million fatigue cycles, it is preferable that bias member 104 operate within its fatigue limit, as dictated by the chosen material and geometry, for the full range of displacement.
  • As mentioned previously, the bias force may generally increase or decrease with displacement of the ends of the bias member 104, as with a conventional spring. In this situation, the bias force (FB) is generally governed by Hooke's Law where FB=KΔX, wherein FB is linearly proportional to the displacement (ΔX) as dictated by the spring constant (K) of the bias member 104. Also as mentioned previously, the bias force may increase or decrease with the time derivative of displacement (i.e., velocity) of the ends of the bias member 104, as with a conventional damper or shock absorber. In this situation, the bias force (FB) is generally linearly proportional to the derivative of displacement (ΔX/ΔT) as dictated by the damper constant (P) of the bias member 104. Preferably, the bias force FB Of the bias member 104 is adjusted such that the disc is restored to a more normal height when the dynamic bias device 100 is implanted. The bias force FB may be adjusted by selecting the spring constant (K) and/or damper constant (P) of the bias member 104 and by pre-loading (compressing) the bias member 104 an initial displacement ΔXi.
  • The necessary bias force FB may be roughly calculated as a function of body weight (BW), the distance of the mounted dynamic bias device 100 from the axis of curvature 60, and the mechanical properties of the surrounding tissues (muscle tissue, connective tissue, joints). The normal net load carried by the lumbar region 12 is roughly 30% BW when laying down, 140% BW when standing, 185% BW when sitting, 215% BW when bending forward, and 250% BW when slouching.
  • With reference to FIG. 16, a bias force versus attachment point displacement curve for the dynamic bias device 100 is shown. The bias force is intended to be sufficiently high to spread the attachment points (e.g., processes of adjacent vertebrae) and restore normal disc height in all postures. For example, in normal standing posture, the bias force is sufficiently high to spread the attachment points as shown in FIG. 16, such that more normal disc size and shape is obtained. As the spine is placed in flexion and extension, the amount of force carried by the dynamic bias device 100 will change as a function of the spring properties, including the spring constant (K) and the compression length of the spring.
  • In a preferred embodiment, the bias force is sufficient to shift the pre-implant (normal posture) distance to the post-implant (normal posture) distance. To prevent excessive compression of the disc, particularly the posterior disc, it is also preferred that the bias force increase significantly as the attachment points come closer, as by extension, lifting and/or poor posture. This is facilitated by the natural increase in bias force of the spring as the distance decreases, and is aided by the damper pad and the compression limit (bottomed out) of the spring. In addition, because the dynamic bias device is intended to limit excessive compression of the posterior disc, and not necessarily intended to limit flexion of the spine, it is also preferable that the bias force approach zero (spring fully extended) at a distance which is less than the extension limit of the dynamic bias device.
  • Thus, by way of example, not limitation, the bias force may be in the range of 1% to 30% BW when laying down. With other postures after implantation, the bias force may be estimated by subtracting the contribution of body weight from the load carried by lumbar region 12, which is approximately 50% BW (head=5% BW; arms=9% BW; trunk=36% BW). As such, the bias force may be in the range of 10% to 90% BW when standing.
  • With reference to FIGS. 4A-4B and 5A-5B, left lateral and posterior views of dynamic bias devices 100 are schematically illustrated as being mounted to adjacent spinous processes 24 S and 24 I of adjacent vertebrae 20 S and 20 I. When two or more dynamic bias devices 100 are utilized per pair of vertebrae as shown in FIGS. 4A and 4B, the dynamic bias devices 100 are preferably mounted substantially equidistant from the median plane 70, or otherwise symmetric about the median plane 70, in order to avoid causing lateral bias or curvature of the spine 10. Note that the dynamic bias devices 100 may be mounted substantially vertical as shown or at an angle to the median plane 70 and satisfy these criteria. When only one dynamic bias device 100 is utilized per pair of vertebrae as shown in FIGS. 5A and 5B, the dynamic bias device 100 is preferably mounted in or near the median plane 70 for the same reason.
  • Although it is preferable to have the dynamic bias device(s) 100 near the median plane 70, substantially equidistant from the median plane 70, or otherwise symmetric about the median plane 70, it is possible to have multiple dynamic bias devices 100 mounted asymmetrically while maintaining balanced bias forces about the median plane 70. The objective is to avoid causing lateral bias or curvature of the spine 10, which is a function of balancing bias forces and moments about the median plane 70.
  • The bias forces are vectors which have a magnitude governed by the properties of the bias member 104, and a direction dictated by the mounting position of the dynamic bias device 100. Each dynamic bias device 100 has two bias force vectors, one for each attachment member 102 at each attachment point. Each bias force vector has a moment arm equal to the distance from the attachment point to the median plane 70. For each attachment point, the product of the moment arm and the vertical component of the bias force vector is the moment or torque applied to the spine 10, and the horizontal component of the bias force vector is the shear applied to the spine 10. Thus, in order to minimize curvature of the spine 10, all of the moments are balanced about the median plane 70 In order to minimize lateral bias on the spine 10, all of the horizontal components of the bias force vectors are balanced about the median plane 70. The easiest way to accomplish this result, of course, is to mount the dynamic bias devices 100 symmetrically about the median plane 70. However, those skilled in the art will recognize that asymmetric mounting arrangements that substantially meet these criteria are also possible.
  • Further, because most protrusions 56 are posterior, the dynamic bias device(s) 100 is/are preferably mounted posterior to the axis of curvature 60. This is advantageous because loss of disc height is most common in the posterior disc 50, the largest amount of mechanical advantage about the anterior disc is obtained posterior to the axis of curvature 60, and the posterior portions of the vertebrae are easiest to access less invasively. However, the dynamic bias device(s) 100 may be mounted at any position relative to the axis of curvature 60 depending on the location of the protrusion 56, as long as the dynamic bias device(s) 100 is/are near the median plane 70, substantially equidistant from the median plane 70, or otherwise symmetric about the median plane 70 as discussed above.
  • Given these criteria, there are many suitable mounting locations or attachment points for the dynamic bias device 100. Some of the possible attachment points are labeled A-N in FIGS. 1A and 1B. Attachment points A-G refer to the lumbar vertebrae 20 (L1-L5), and attachment points H-N refer to the sacral vertebrae 30 (particularly S1). The attachment points A-G of the lumbar region 12 are equally applicable to the thoracic and cervical regions of the spine 10, which are not illustrated for purposes of simplicity only.
  • In the lumbar region 12, attachment points A and B refer to the left lateral and right lateral surfaces of the spinous process 24; attachment point C refers to the posterior surface of the spinous process 24; attachment points D and E refer to the posterior surfaces of the left and right laminae 23; and attachment points F and G refer to the distal ends of the left and right transverse processes 25.
  • In the sacrum 14, attachment points H and I refer to the left lateral and right lateral surfaces of the superior median sacral crest 31; attachment points K and L refer to the posterior surfaces of the sacral laminae 33 between the median sacral crest 31 and the intermediate sacral crests 32; and attachment points M and N refer to posterior surface between the intermediate sacral crests 32 and the lateral sacral crests 34.
  • A wide variety of sets of attachment points are possible, a non-exhaustive list of which is set forth herein. For single dynamic bias device 100 mounting, the nomenclature is (X1Y1) where X1 is the attachment point on vertebra X, and Y1 is the attachment point on vertebra Y. For double dynamic bias device 100 mounting, the nomenclature is (X1Y1, X2Y2) where X1 is the attachment point of the first dynamic bias device 100 on vertebra X, Y1 is the attachment point of the first dynamic bias device 100 on vertebra Y, X2 is the attachment point of the second dynamic bias device 100 on vertebra X, and Y2 is the attachment point of the second dynamic bias device 100 on vertebra Y. Vertebrae X and Y refer to any two different vertebrae, which are usually, but not necessarily, adjacent. In addition, vertebrae X and Y may be superior and inferior, respectively, or vice-versa.
  • To illustrate the attachment point nomenclature, reference may be made to FIGS. 4B and 5B. In FIG. 4B, a first dynamic bias device 100 is attached to the left lateral surface of the two spinous processes, and a second dynamic bias device 100 is attached to the right lateral surface of the two spinous processes. Thus, the set of attachment points for the arrangement of FIG. 4B is (AA, BB). In FIG. 5B, only one dynamic bias device 100 is attached to the posterior surface of the two spinous processes. Thus, the set of attachment points for the arrangement of FIG. 5B is (CC).
  • By way of example, not limitation, the following sets of attachment points may be used to satisfy the above-referenced criteria with regard to balancing moments and forces about the median plane 70. For single dynamic bias device 100 mounting: (CC); and (CJ) are preferred. For double dynamic bias device 100 mounting: (AA, BB); (DD, EE); (FF, GG); (AH, BI); (DK, EL); (FK, GL); (DM, EN); and (FM, GN) are preferred. Also for double dynamic bias device 100 mounting: (AD, BE); (AF, BG); (AK, BL); (AM, BN); (DH, El); (DF, EG); (FH, GI); (CA, CB); (CH, CI); (CD, CE); (CF, CG); (CK, CL); (CM, CN); (JA, JB); (JH, JI); (JD, JE); and (JF, JG) are possible. For more than double mounting, any combination of these sets may be used. Generally, the more posterior the attachment points, the less invasive the procedure will be. Attachment points A, B, C, H and I are preferred for this reason. In addition, to avoid interfering with the motion of the vertebrae, the dynamic bias device 140 is preferably disposed laterally or posteriorly of the spinous processes 24, as opposed to under and between the spinous processes 24.
  • The dynamic bias device 100 may be attached to these points by conventional surgical techniques, except as described herein. The posterior musculature and connective tissues may be dissected to expose the desired attachment points. If desired, any disc protrusions 56 may be removed, in whole or in part, using a conventional discectomy procedure. Also if desired, any other abnormal spinal growths or protrusions may be removed. However, for many disc protrusions 56, it is anticipated that conventional traction or separation techniques may be employed to temporarily retract the protrusion 56 into the normal disc space until the dynamic bias devices are implanted.
  • In order to establish separation of the vertebrae, the spine may be placed in traction or conventional intervertebral separation tools may be used. Alternatively, the dynamic bias device 100 may be preloaded such that when the device is released after attachment, the bias force establishes the desired amount of separation.
  • Pilot holes are drilled as needed, such as for the use of bushings 330, 340 and/or 350 (described with reference to FIGS. 7A-7B, 8A-8B and 9A-9B hereinafter). If attachment points A, B, H and I are to be used, such as with the use of bushing 320 (described with reference to FIGS. 6A-6D hereinafter), a hole 90 and counter-bore 92 may be drilled into the spinous process 24. The device(s) 100 are then attached to the desired attachment points in accordance with the hardware being used, and the site is subsequently surgically closed.
  • With reference to FIGS. 6A-6D, 7A-7B, 8A-8B and 9A-9B, various embodiments of bushings 320, 330, 340, and 350, respectively, are illustrated. As mentioned previously, the attachment members 102 may comprise a wide variety of mechanical connection designs, and may incorporate into their design, or be used in combination with, other machine elements such as bushings 320, 330, 340, and 350. Bushings 320, 330, 340, and 350 are adapted to mount one or two dynamic bias devices 100. As illustrated, bushings 320, 330, 340, and 350 are adapted to receive attachment members 102 in the form of loops or the like, but may be modified to receive other structures. A primary function of bushings 320, 330, 340, and 350 is to isolate movement of the attachment members 102 from the vertebrae to which they are attached. Thus, the bushing to bone (vertebrae) interface is static, while the bushing to attachment member interface is dynamic. This reduces if not eliminates the abrasive degradation of the vertebrae due to the attachment of the dynamic bias device 100. The orientation of the vertebral surface at the attachment points will determine the best bushing scheme.
  • With reference to FIGS. 6A-6B, end and exploded views, respectively, of a bushing 320 are illustrated. Bushing 320 is particularly suitable for attachment to the spinous process 24 as shown in FIG. 6C, or attachment points A, B, H and I as illustrated in FIG. 1A. Bushing 320 may be attached to the spinous process 24 utilizing a conventional fastener 300, which includes bolt 302, nut 304 and washers 306 and 308. Preferably, the fastener 300 is a lock fastener such that it will not have a tendency to unscrew with relative motion of the attachment members 102. However, the nut 304 is not tightened so much as to inhibit rotational movement of the attachment members 102. Fastener 300 may alternatively comprise a key and pin (e.g., cotter pin). When fully assembled, the attachment members 102 are disposed around the shaft of the bolt 302 on either side of the bushing 320 and between the washers 306 and 308.
  • Bushing 320 includes a male fitting 321 which fits into a female fitting 324. The male fitting 321 includes a shank portion 322 and a head portion 323. Similarly, the female fitting 324 includes a shank portion 325 and a head portion 326. The female fitting 324 has an inside diameter sized to accommodate the shank 322 of the male fitting 321, and the male fitting 321 has an inside diameter sized to accommodate the bolt 302 of the fastener 300. The outside surface of the shank 322 of the male fitting 321 and the inside surface of the shank 325 of the female fitting 324 may include mating threads.
  • The size of the head 323/326 to bone interface is preferably maximized to minimize stress concentration and to distribute torsional loads over a large surface area. The size of the female shank 25 and the corresponding size of the hole 90 drilled through the spinous process 24 are chosen to minimize stress concentration and minimize the loss of bone integrity. A counter-bore 92 may be used to flatten and thereby maximize the contact surface area of the head 323/326 to bone interface, as illustrated in FIG. 6D.
  • The materials of the fastener 300 and bushing 320 may comprise any suitable implantable material capable of withstanding high fatigue. For example, all components could be comprised of 300 or 400 series stainless steel, titanium alloy 6-4, or MP35N alloy. Preferably, all components would be made of the same or similar material to reduce galvanic corrosion. The surfaces of the fastener 300 and bushing 320 that engage the attachment members 102 of the dynamic bias device 100 are preferably smooth to reduce friction and wear. The surfaces of the bushing 320 that engage the vertebrae may have a roughened surface (e.g., knurled) to reduce the likelihood of relative movement therebetween. In addition, the surfaces of the bushing 320 that engage the vertebrae may have a porous sintered surface to facilitate solid bone growth, thereby further securing the bushing 320. Coatings and surface treatments may be utilized to reduce or increase friction where desired, and biological response where tissue interface is likely.
  • With reference to FIGS. 7A-7B, end and exploded views, respectively, of a bushing 330 are illustrated. Except as described herein, bushing 330 is substantially the same in design, function and use as bushing 320. Bushing 330 is adapted to mount one or (preferably) two dynamic bias devices 100. Bushing 330 is particularly suitable for attachment points C and J as illustrated in FIG. 1B. Bushing 330 may be attached to the vertebrae 20/30 utilizing a conventional bone screw 310, which may be modified in diameter, length and thread type for the particular attachment site and condition.
  • Bushing 330 includes two male fittings 331 which fit into a female fitting 334. The male fittings 331 each include a shank portion 332 and a head portion 333. Similarly, the female fitting 334 includes two shank portions 335 and two head portions 336. The female fitting 334 has an inside diameter sized to accommodate the shanks 332 of the male fittings 331, and the male fittings 331 have an inside diameter sized to accommodate the bolt 302 of the fastener 300. The outside surfaces of the shanks 332 of the male fittings 331 and the inside surfaces of the shanks 335 of the female fitting 334 may include mating threads. When fully assembled, the attachment members 102 are disposed around the shanks 335 on either side of heads 336 of the female fitting 334 and between the heads 333 of the male fittings 331.
  • With reference to FIGS. 8A-8B, end and exploded views, respectively, of a bushing 340 are illustrated. Except as described herein, bushing 340 is substantially the same in design, function and use as bushing 330. Bushing 340 is adapted to mount one dynamic bias device 100. Bushing 340 is particularly suitable for attachment points C, D, E, F, G, J, K, L, M and N, but may also be used for attachment points A, B, H and I as illustrated in FIGS. 1A and 1B. Bushing 340 may be attached to the vertebrae 20/30 utilizing a conventional bone screw 310, which may be modified in diameter, length and thread type for the particular attachment site and condition.
  • Bushing 340 includes a male fitting 341 which fits into a female fitting 344. The male fitting 341 includes a shank portion 342 and a head portion 343. Similarly, the female fitting 344 includes a shank portion 345 and a head portion 346. The female fitting 344 also includes a flange 347 connecting the bone screw 310 to the bushing 340. The female fitting 344 has an inside diameter sized to accommodate the shank 342 of the male fitting 341, and the male fitting 341 has an inside diameter sized to accommodate the bolt 302 of the fastener 300. The outside surface of the shank 342 of the male fitting 341 and the inside surface of the shank 345 of the female fitting 344 may include mating threads. When fully assembled, the attachment member 102 is disposed around the shank 345 on the female fitting 344 and between the heads 343/346 of the fittings 341/344. When mounted, the axis of the shank 345 of bushing 340 is oriented parallel to the mounting surface.
  • With reference to FIGS. 9A-9B, end and exploded views, respectively, of a bushing 350 are illustrated. Except as described herein, bushing 350 is substantially the same in design, function and use as bushing 340. Bushing 350 is adapted to mount one dynamic bias device 100. Bushing 350 is particularly suitable for attachment points C, D, E, F, G, J, K, L, M and N, but may also be used for attachment points A, B, H and I as illustrated in FIGS. 1A and 1B. Bushing 350 may be attached to the vertebrae 20/30 utilizing a conventional bone screw 310, which may be modified in diameter, length and thread type for the particular attachment site and condition. In this particular embodiment, the fastener 300 is formed integrally with the bone screw 310.
  • Bushing 350 includes a male fitting 351 which fits into a female fitting 354. The male fitting 351 includes a shank portion 352 and a head portion 353. Similarly, the female fitting 354 includes a shank portion 355 and a head portion 356. The female fitting 354 has an inside diameter sized to accommodate the shank 352 of the male fitting 351, and the male fitting 351 has an inside diameter sized to accommodate the bolt 302, which is integral with the bone screw 310. The outside surface of the shank 352 of the male fitting 351 and the inside surface of the shank 355 of the female fitting 354 may include mating threads. When fully assembled, the attachment member 102 is disposed around the shank 355 on the female fitting 354 and between the heads 353/356 of the fittings 351/354. When mounted, the axis of the shank 355 of bushing 350 is oriented perpendicular to the mounting surface.
  • With reference to FIGS. 10A-10C, side views of a dynamic bias device 110 are illustrated in a no-load condition, in a compression load condition, and in cross-section, respectively. Except as described herein, dynamic bias device 110 is substantially the same in design, function and use as the generic device 100 described previously. Dynamic bias device 110 includes a barrel 111 in which piston 112 is slidably disposed. A bias member in the form of a spring 113 is disposed in the barrel 111. Longitudinal displacement of the barrel 111 relative to the piston 112 causes compression (or extension) of the spring 113. The spring 113 provides a bias force which increases (or decreases) linearly with displacement as discussed previously. A flexible housing (not shown) may be placed about the dynamic bias device 110 to isolate the moving parts 111/112 from the surrounding tissue when implanted.
  • An adjustable arm 114 may be connected to the piston 112. The arm 114 and the barrel 111 include holes 115 or other suitable attachment members, which may be used in combination bushings 320, 330, 340 and 350, to attach the dynamic bias device 110 to the vertebrae. The adjustable arm 114 and the piston 112 may include mating threads such that rotation of the arm 114 causes the arm 114 to effectively lengthen or shorten the piston 112. This allows the distance between the holes 115 to be varied to accommodate different attachment locations and different anatomies. This also allows the dynamic bias device to be preloaded by extending the effective length of the piston 112 beyond the distance between attachment points.
  • A collar 116 is provided to limit the extended length of the dynamic bias device 110. The collar 116 may include threads that mate with threads inside the barrel 111 such that the collar 116 is adjustable, and thus the extended length is adjustable. The collar 116 may also include an elastomeric bumper pad to dampen impact between the piston 112 and the collar when the device 110 is filly extended. Similarly, a elastomeric bumper pad 117 may be provided in the barrel 111 to dampen impact between the piston 112 and the barrel 111 when the device 110 is filly collapsed.
  • With reference to FIG. 11A, a cross-sectional view of a dynamic bias device 120 is illustrated. Except as described herein, dynamic bias device 120 is substantially the same in design, function and use as dynamic bias device 110 discussed with reference to FIGS. 10A-10C. Dynamic bias device 120 includes a barrel 121 in which piston 122 is slidably disposed. A bias member 123 in the form of a compressed or evacuated fluid (liquid or gas or a combination of both) is disposed in the barrel 121 and sealed relative to the piston 122 by piston ring 128. The barrel 121 and piston 122 may define a closed volume or an exhaust reservoir 129 may be used as shown. The bias fluid 123 is in fluid communication with the exhaust reservoir 129 by way of an exhaust port through the wall of the barrel 121. The exhaust reservoir 129 may comprise an expandable annular bag as shown, or other suitable structure. If a closed volume is used, longitudinal displacement of the barrel 121 relative to the piston 122 simply causes a change in pressure of the fluid 123. If an exhaust reservoir 129 is used as shown, longitudinal displacement of the barrel 121 relative to the piston 122 causes a change in pressure of the fluid 123 and flow of fluid 123 into the exhaust reservoir 129 via the exhaust port. The pressure of the fluid 123 and the size of the exhaust hole dictates the bias force which increases (or decreases) with the time derivative of displacement as discussed previously.
  • A flexible housing (not shown) may be placed about the dynamic bias device 130 to isolate the moving parts 121/122 from the surrounding tissue when implanted. The housing may be used to define the exhaust reservoir 129. An adjustable arm 124 may be connected to the piston 122. The arm 124 and the barrel 121 include holes 125 or other suitable attachment members to attach the dynamic bias device 120 to the vertebrae. The adjustable arm 124 and the piston 122 may include mating threads to effectively lengthen or shorten the piston 122. An adjustable collar 126 may be provided including mating threads such that the collar 126 is adjustable, and thus the extended length of the dynamic bias device 120 is adjustable. The collar 126 may include an elastomeric bumper pad (not shown) and an elastomeric bumper pad 127 may be provided in the barrel 121 to dampen impact between the piston 122 and the barrel 121.
  • With reference to FIG. 11B, a cross-sectional view of a dynamic bias device 130 is illustrated. Except as described herein, dynamic bias device 130 is substantially the same in design, function and use as the combination of dynamic bias device 110 discussed with reference to FIGS. 10A-10C and dynamic bias device 120 described with reference to FIG. 11A.
  • Dynamic bias device 130 includes a barrel 131 in which piston 132 is slidably disposed. A bias member is the form of a spring 133A is disposed in the barrel 131. Longitudinal displacement of the barrel 131 relative to the piston 132 causes compression (or extension) of the spring 133. The spring 133 provides a bias force which increases (or decreases) linearly with displacement as discussed previously. In addition, a bias member 133B in the form of a compressed or evacuated fluid (liquid or gas) is disposed in the barrel 131 and sealed relative to the piston 132 by piston ring 138.
  • The barrel 131 and piston 132 may define a closed volume or an exhaust reservoir 129 may be used as shown. The bias fluid 133 is in fluid communication with the exhaust reservoir 139 by way of an exhaust port through the wall of the barrel 131. The exhaust reservoir 139 may comprise an expandable annular bag as shown, or other suitable structure. If a closed volume is used, longitudinal displacement of the barrel 131 relative to the piston 132 simply causes a change in pressure of the fluid 133. If an exhaust reservoir 139 is used as shown, longitudinal displacement of the barrel 131 relative to the piston 132 causes a change in pressure of the fluid 133 and flow of fluid 133 into the exhaust reservoir 139 via the exhaust port. The pressure of the fluid 133 and the size of the exhaust hole dictates the bias force which increases (or decreases) with the time derivative of displacement as discussed previously. Thus, the bias members 133A/133B effectively act as a combined spring and damper.
  • A flexible housing (not shown) may be placed about the dynamic bias device 130 to isolate the moving parts 131/132 from the surrounding tissue when implanted. The housing may be used to define the exhaust reservoir 139. An adjustable arm 134 may be connected to the piston 132. The arm 134 and the barrel 131 include holes 135 or other suitable attachment members to attach the dynamic bias device 130 to the vertebrae. The adjustable arm 134 and the piston 132 may include mating threads to effectively lengthen or shorten the piston 132. An adjustable collar 136 may be provided including mating threads such that the collar 136 is adjustable, and thus the extended length of the dynamic bias device 130 is adjustable. The collar 136 may include an elastomeric bumper pad (not shown) and an elastomeric bumper pad 137 may be provided in the barrel 131 to dampen impact between the piston 132 and the barrel 131.
  • With reference to FIGS. 12A-12B, rear and side views of dynamic bias device 140 are illustrated in no-load condition. FIG. 12C illustrates the dynamic bias device 140 subjected to a compression load. Except as described herein, dynamic bias device 140 is substantially the same in design, function and use as the generic device 100 described previously. Although movement of the dynamic bias device 140 in compression and extension is substantially linear and parallel to the axis of curvature 60, as with dynamic bias device 100, some lateral or posterior-anterior motion is present, but preferably minimized. Dynamic bias device 140 includes bias member 142 and loops 144 or other suitable attachment members, which may be used in combination bushings 320, 330, 340 and 350, to attach the dynamic bias device 140 to the vertebrae. The bias member 142 is may be a semi-circular or semi-elliptical leaf spring, which may be a single plate as shown or a series of laminated plates. Relative longitudinal displacement of the attachment members 144 causes compression (or extension) of the leaf spring 142. The leaf spring 142 provides a bias force which increases (or decreases) with displacement as discussed previously.
  • The radius or axis of curvature of the leaf spring 142 is preferably maximized such that displacement of the attachment members 144 is substantially linear, but should not be so high as to result in buckling or inversion in compression. By way of example, not limitation, the radius or axis of curvature may range from half the distance between the attachment points to approximately 10 cm. Of course, half the distance between attachment points will vary depending on the location of each attachment point, but will likely be in the range of 1.0 to 3.0 cm for attachment points between adjacent processes.
  • The displacement of the apex 143 is preferably of the leaf spring 142 minimized to minimize disturbance of and interference from surrounding tissue (bone, muscle, connective tissue, nerves, etc.). The apex 143 may face anteriorly, but preferably faces posteriorly or laterally to reduce interference with tissue close to the spinal column. The dynamic bias device 140, and particularly the leaf spring 142, is preferably disposed laterally or posteriorly of the spinous processes 24 to avoid interference with movement of the vertebrae.
  • With reference to FIGS. 13A-13C, various alternative dynamic bias devices 150, 160 and 170 are illustrated in side and posterior views. Except as described herein, dynamic bias devices 150, 160 and 170 are substantially the same in design, function and use as the dynamic bias device 140 discussed with reference to FIGS. 12A-12C.
  • Dynamic bias device 150 as seen in FIG. 13A includes bias member 152 in the form of an articulated leaf spring, and attachment members 154. Articulated leaf spring 152 reduces the horizontal range of movement by utilizing a plurality of articulations 153 having a smaller radius or axis of curvature. The reduced horizontal range of movement of the bias member 152 reduces the amount of disturbance and interference from surrounding tissue (bone, muscle, connective tissue, nerves, etc.).
  • Dynamic bias device 160 as seen in FIG. 13B includes a plurality of bias members 162 in the form of leaf springs (shown) or articulated leaf springs (not shown), and attachment members 164. Utilizing a plurality of leaf springs 162 increases stability of the dynamic bias device 160 and allows for greater net bias forces to be delivered to the attachment members 164 and the vertebrae attached thereto.
  • Dynamic bias device 170 as seen in FIG. 13C includes a plurality of bias members 172 in the form of leaf springs (shown) or articulated leaf springs (not shown). The dynamic bias device 170 also includes attachment members 174 in the form of inverted semi-circular loops. The inverted semi-circular loops 174 permit the device 170 to be attached to the inferior and superior sides spinous processes of adjacent vertebrae, such that the attachment members 174 are disposed between adjacent spinous processes but the bias members 172 are disposed laterally of the spinous processes to avoid interference with movement of the vertebrae.
  • Dynamic bias devices 110, 120, 130, 140, 150, 160 and 170 may be used (i.e., implanted) substantially as described with reference to generic dynamic bias device 100. As mentioned previously, one or more reinforcement members 200 may be used in combination with one or more dynamic bias devices 100. The reinforcement members 200 may be used to reinforce the disc, restore disc height and/or bear some or all of the load normally carried by the annulus. The reinforcement members 200 are relatively rigid and thus serve to reinforce the disc 50, and particularly the annulus 52, where inserted. In addition, the reinforcement members 200 may have a relatively large profile when implanted and thus increase disc height.
  • The reinforcing members 200 may be used singularly or in groups, depending on the increase in disc 50 height desired and/or the amount of reinforcement of the annulus 52 desired. For example, the reinforcing members 200 may be stacked as illustrated in FIG. 2B or inserted side-by-side as illustrated in FIG. 15R. In addition, the reinforcing members 200 may be located in virtually any portion of the annulus 52. Preferably, the reinforcing members 200 are substantially symmetrically disposed about the median plane 70 to avoid causing curvature of the spine 10. Although the reinforcing members 200 may be inserted, in part or in whole, into the nucleus 54, it is preferable to insert them into the annulus 52 for purposes of stability and load carrying. Specifically, to provide stability, it is desirable to symmetrically locate the reinforcing members 200 as far as reasonably possible from the median plane 70, or to span as great a distance as possible across the median plane 70. In addition, because the annulus 52 of the disc 50 is believed to carry the majority of the load, particularly in the lumbar region 12, the reinforcing members 200 are preferably placed in the annulus 52 to assume the load normally carried thereby, and reinforce the load bearing capacity of the annulus 52, without hindering the normal mobility function of the disc 50.
  • The reinforcing members 200 may comprise expandable members such as self-expanding members 210 or inflatable members 220. Alternatively, the reinforcing members 200 may comprise unexpandable members such as reinforcement bars 230. When implanting each type of reinforcement member 210/220/230, it is preferable to maintain the integrity of the annulus 52. Accordingly, space in the annulus 52 for the reinforcing members 200 is preferably established by dilation or the like, although some amount of tissue removal may be used.
  • The expandable reinforcement members 210/220 are useful because they may be delivered in a low profile, unexpanded condition making it easier to traverse the very tough and fibrous collagen tissue of the annulus 52. For similar reasons, the reinforcement bars 230 are useful because they may have a small diameter and a sharpened tip. Although it is possible to insert the expandable reinforcing members 210/220 into the annulus 52 in their final expanded state, it is desirable to deliver the expandable reinforcing members 210/220 into the annulus 52 in an unexpanded state and subsequently expand them in order to minimize invasiveness and resistance to insertion.
  • The self-expanding reinforcing member 210 may comprise a solid or semi-solid member that self-expands (e.g., by hydration) after insertion into the annulus. Examples of suitable materials for such solid or semi-solid members include solid fibrous collagen or other suitable hard hydrophilic biocompatible material. If the selected material is degradable, the material may induce the formation of fibrous scar tissue which is favorable. If non-degradable material is selected, the material must be rigid and bio-inert. The self-expanding reinforcing member 210 preferably has an initial diameter that is minimized, but may be in the range of 25% to 75% of the final expanded diameter, which may be in the range of 0.3 to 0.75 cm, or 10% to 75% of the nominal disc height. The length of the self-expanding member 210 may be in the range of 1.0 to 6.0 cm, and preferably in the range of 2.0 to 4.0 cm.
  • The inflatable reinforcing member 220 may comprise an expandable hollow membrane capable of inflation after insertion into the annulus. An example of a suitable inflatable structure is detachable balloon membrane filled with a curable material. The membrane may consist of a biocompatible and bio-inert polymer material, such as polyurethane, silicone, or polycarbonate-polyurethane (e.g., Corethane). The curable filler material may consist of a curable silicone or polyurethane. The filler material may be curable by chemical reaction (e.g., moisture), photo-activation (e.g., UV light) or the like. The cure time is preferably sufficiently long to enable activation just prior to insertion (i.e., outside the body) and permit sufficient time for navigation and positioning of the member 220 in the disc. However, activation may also take place inside the body after implantation. The inflatable reinforcing member 220 preferably has an initial deflated diameter that is minimized, but may be in the range of 25% to 75% of the final inflated diameter, which may be in the range of 0.3 to 0.75 cm, or 10% to 75% of the nominal disc height. The length of the inflatable member 220 may be in the range of 1.0 to 6.0 cm, and preferably in the range of 2.0 to 4.0 cm.
  • The reinforcement bars 230 may comprise a rigid, solid or hollow bar having a sharpened tip. The reinforcement bars 230 may comprises stainless steel mandrels, for example, having a diameter in the range of 0.005 to 0.100 inches, preferably in the range of 0.010 to 0.050 inches, and most preferably in the range of 0.020 to 0.040 inches, and a length in the range of 1.0 to 6.0 cm, and preferably in the range of 2.0 to 4.0 cm. The reinforcement bars 230 may be straight for linear insertion, or curved to gently wrap with the curvature of the annulus during insertion. In addition, the outer surface of the reinforcement bars 230 may have circular ridges or the like that the permit easy insertion into the annulus 52 but resist withdrawal and motion in the annulus following implantation. Other suitable materials for reinforcement bars 230 include titanium alloy 6-4, MP35N alloy, or super-elastic nickel-titanium alloy.
  • Referring now to FIGS. 14A-14D, various tools 410, 420 and 430 are shown individually and assembled. The tools 410, 420 and 430 may be used to implant the reinforcement devices 210/220/230 discussed above. The tools include a rigid, sharpened, hollow needle 410, a semi-rigid, sharpened, hollow curved needle 420, and a sharpened stylet 430. As seen in FIG. 14D, the sharpened stylet 430 fits into the semi-rigid needle 420 which fits into the rigid needle 410.
  • With specific reference to FIG. 14A, the rigid hollow needle 410 includes a hollow shaft 412 and a grip or handle 414. The shaft 412 includes a sharpened tip 413 to facilitate insertion into and pass through the surrounding tissue. The shaft 412 is preferably made of a rigid metal such as a stainless steel hypodermic tube. The grip 414 may comprise a polymer and may be formed by insert injection molding with the shaft 412 inserted into the mold.
  • With specific reference to FIG. 14B, the semi-rigid curved needle 420 includes a hollow shaft 422 a hub 424. The shaft 422, which includes a sharpened tip 423, is longer than the rigid needle 410 and has an outside diameter sufficiently small to fit into the rigid needle 410. The shaft 422 is preferably made of a semi-rigid polymer or composite. The shaft 422 includes a curved distal portion 426 that may be straightened (shown in phantom) upon insertion of the semi-rigid needle 420 into the lumen of the rigid needle 410. The hub 424 may include a fitting 425 to facilitate connection to a fluid source or a pressure source (e.g., a syringe).
  • With specific reference to FIG. 14C, the sharpened stylet 430 includes a flexible shaft 432 and a sharpened distal end 433. The shaft 432 is longer than the both the rigid needle 410 and the semi-rigid needle 420, and may have a length on the order of 10 to 60 cm. The shaft 432 also has an outside diameter sufficiently small to fit into the semi-rigid needle 420. The shaft 422 preferably has a flexible but pushable construction incorporating a rigid metal such as stainless steel, or super-elastic nickel-titanium alloy. The sharpened stylet 430 is preferably highly elastic, to resist permanent set upon insertion into the curved portion 426 of the semi-rigid needle 420.
  • With general reference to FIGS. 15A-15J, the steps for implanting a self-expanding reinforcement member 210 are illustrated. It should be understood that the procedure for implanting a single member 210 in the anterior annulus 52 is shown for purposes of illustration, not limitation. All of the variables with regard to quantity, location, orientation, etc. discussed previously may be implemented by varying the generic procedure described hereinafter.
  • Initially, the sharpened stylet 430, semi-rigid needle 420 and rigid needle 410 are assembled as shown in FIG. 14D. As shown in FIG. 15A, the distal portion of the assembly 410/420/430 is inserted into the disc 50 as in a conventional discogram procedure. The assembly 410/420/430 is advanced until the distal tip 413 of the rigid needle is proximate the anterior curvature of the annulus 52, near the anterior side of the nucleus 54, as seen in FIG. 15B. The semi-rigid needle 420 (alone or with stylet 430) is advanced relative to the rigid needle 410 until the curved portion 426 of the semi-rigid needle exits the distal tip 413 of the rigid needle 410 and the desired amount of curvature is established, as seen in FIG. 15C. The curved portion 426 may be advanced until the tip 423 is substantially parallel to the tangent of the anterior annulus 52 curvature. The sharpened stylet 430 is advanced relative to the semi-rigid needle 420 to the desired position within the anterior annulus 52, as shown in FIG. 15D. The semi-rigid needle 420 and the rigid needle 410 are completely withdrawn from the stylet 430, leaving the stylet in position as shown in FIG. 15E.
  • A flexible dilator 440 is advanced over the stylet 430 to dilate the annulus 52, as seen in FIG. 15F. The flexible dilator 440 is similar to semi-rigid needle 420 except that the dilator includes a blunt distal tip and is relatively more flexible, and has larger inner and outer diameters. Note that one or more dilators 440 may be advanced co-axially about the stylet 430 until the annulus is sufficiently dilated to accept the self-expandable member 210. The stylet 430 is then withdrawn from the flexible dilator 440 and the self-expandable member 210 is introduced into the lumen of the flexible dilator 440 using a push bar 450, as shown in FIG. 15G. Alternatively, the dilator 440 may be removed in favor of a flexible hollow catheter with a large inner diameter to facilitate delivery of member 210. The push bar 450 is similar to stylet 430 except that the distal tip of the push bar 450 is blunt. Alternatively, the push bar 450 may simply comprise the stylet 430 turned around, thus using the proximal blunt end of the stylet 430 as the push bar 450. The push bar 450 is advanced until the member 210 is in the desired position, as seen in FIG. 15H. To facilitate positioning the member 210, radiographic visualization may be used to visualize the distal end of the push bar 450, which is formed of radiopaque material and may include radiopaque markers. In addition, the member may be loaded with a radiopaque material to facilitate radiographic visualization thereof.
  • After the member 210 is in the desired position, the flexible dilator 440 is retracted from the push bar 450 while maintaining position of the member 210 with the push bar. The push bar 450 is then removed leaving the member 210 in place. If necessary, the procedure may be repeated for additional member implants 210. The member 210 is then allowed to expand over time, perhaps augmented by placing the spine 10 in traction. Alternatively, the spine 10 may be placed in traction prior to beginning the procedure as discussed with reference to the procedure for implanting dynamic bias device 100.
  • With reference to FIGS. 15K-15L, the steps for implanting an inflatable reinforcement member 220 are illustrated. In this procedure, the steps outlined with reference to FIGS. 15A- 15F are followed. Specifically, the same steps are followed up to and including the step of advancing the flexible dilator 440 over the stylet 430 to dilate the annulus 52, and thereafter removing the stylet 430 from the flexible dilator 440. Using a catheter 460, the inflatable member 220 is introduced into the dilator 440 and advanced until the member 220 is in the desired position, as shown in FIG. 15K. The inflatable member 220 is connected to the distal end of the catheter 460, which includes a flexible but pushable shaft 462 and an inflation port 464. The flexible dilator 440 is retracted from the catheter 460 while maintaining position of the member 220.
  • With the member 220 in the desired position, which may be confirmed using radiographic visualization as described above, the proximal inflation port 464 is connected to a syringe (not shown) or other suitable inflation apparatus for injection of the curable filler material. The filler material is then activated and the desired volume is injected into the catheter 460 via the inflation port 464, as seen if FIG. 15L. The filler material is allowed to cure and the catheter 460 is gently torqued to break the catheter 460 from the solid member 220. This break-away step may be facilitated by an area of weakness at the juncture between the distal end of the catheter 460 and the proximal end of the member 220. The catheter 460 is then removed leaving the member 220 in place. If necessary, the procedure may be repeated for additional member implants 220.
  • With reference to FIGS. 15M-15R, the steps for implanting a reinforcement bar 230 are illustrated. As seen in FIG. 15M, the disc 50 includes a protrusion or bulge 56, which is preferably, but not necessarily, reduced or eliminated before insertion of the reinforcement bar 230. This may be done by separating the adjacent vertebrae 20. In order to establish separation of the vertebrae 20, the spine 10 may be placed in traction or conventional intervertebral separation tools may be used. After the bulge 56 is reduced or eliminated, similar steps are followed as outlined with reference to FIGS. 15A-15C.
  • Delivery of a single reinforcement bar 230 into the posterior annulus 52 is illustrated. Specifically, the distal portion of the assembly 410/420/450 is inserted into the disc 50 as in a conventional discogram procedure. The assembly 410/420/450 is advanced until the distal tip 413 of the rigid needle 410 just penetrates the posterior side of the annulus 52, as seen in FIG. 15N. The semi-rigid needle 420 (alone or with bar 230) is advanced relative to the rigid needle 410 until the curved portion 426 of the semi-rigid needle 420 exits the distal tip 413 of the rigid needle 410 and the desired amount of curvature is established, as shown in FIG. 15N. The curved portion 426 may be advanced until the tip 423 is substantially parallel to the posterior annulus 52.
  • Using the push bar 450, the reinforcement bar 230 with its sharpened tip is pushed into the annulus 52 as seen in FIG. 150. The reinforcement bar 230 is advanced into the annulus 52 with the push bar 450 until the bar 230 is in the desired position, as seen in FIG. 15P, which may be confirmed using radiographic visualization as described above. The push bar 450 is then retracted, leaving the reinforcement bar 230 in place, as shown in FIG. 15P. The semi-rigid needle 420 and the rigid needle 410 are then removed, as shown in FIG. 15Q, or, if necessary, the procedure may be repeated for additional reinforcement bar implants 230, as shown in FIG. 15R. Presence of the reinforcement bars 230 serves to keep the disc 50, and particularly the bulge 56, in a more normal condition, and to protect against continued bulging, thus easing nerve impingement.
  • From the foregoing, those skilled in the art will appreciate that the present invention provides dynamic bias devices 100, 110, 120, 130, 140, 150, 160, and 170, in addition to reinforcement devices 210, 220, and 230, which may be used individually or in combination, to eliminate nerve impingement associated with a damaged disc 50, and/or to reinforce a damaged disc, while permitting relative movement of the vertebrae 20 S and 20 I adjacent the damaged disc. The present invention also provides minimally invasive methods of implanting such devices as described above.
  • Those skilled in the art will recognize that the present invention may be manifested in a variety of forms other than the specific embodiments described and contemplated herein. Accordingly, departures in form and detail may be made without departing from the scope and spirit of the present invention as described in the appended claims.

Claims (20)

  1. 1. A method of treating pain associated an intervertebral disc disposed between a first vertebra and a second vertebra in an adult human spine having a median plane and an axis of curvature, the method comprising the steps of:
    identifying the intervertebral disc causing pain;
    providing one or more implantable devices, each having a first vertebral attachment member, a second vertebral attachment member, and a bias force member applying a bias force therebetween while permitting near normal relative motion therebetween;
    attaching the first attachment member of each implantable device to the first vertebra; and
    attaching the second attachment member of each implantable device to the second vertebra such that the bias force members exert a net bias force balanced about the median plane to increase separation of the first and second vertebrae.
  2. 2. A method as in claim 1, wherein the first and second vertebrae have spinous processes, and wherein the implantable device is disposed posterior of the spinous processes.
  3. 3. A method as in claim 1, wherein the first and second vertebrae have spinous processes, and wherein the implantable devices are disposed lateral of the spinous processes.
  4. 4. A method as in claim 1, wherein the bias force member of each implantable device is pre-loaded with a compression load prior to the step of attaching the second attachment member.
  5. 5. A method as in claim 1, wherein the first and second vertebrae are partially separated prior to the step of attaching the second attachment member.
  6. 6. A method as in claim 1, wherein the intervertebral disc has a protrusion, further comprising the step of cutting away at least a portion of the protrusion.
  7. 7. A method as in claim 1, wherein the intervertebral disc has an annulus, further comprising the steps of:
    providing an implantable reinforcement member; and
    implanting the reinforcement member into the annulus of the intervertebral disc.
  8. 8. An implantable system for treating an intervertebral disc disposed between a first vertebra and a second vertebra in an adult human spine having a median plane and an axis of curvature, the system comprising:
    a first vertebral attachment member;
    a second vertebral attachment member; and
    a bias member applying a net bias force between the first vertebral attachment member and the second vertebra attachment member, wherein the bias member permits near normal relative motion between the first and second vertebrae, and the net bias force is substantially symmetric about the median plane.
  9. 9. An implantable system as in claim 8, wherein the bias member has a substantially linear displacement.
  10. 10. An implantable system as in claim 9, wherein the displacement is substantially parallel to the axis of curvature of the first and second vertebrae.
  11. 11. An implantable system as in claim 8, wherein the bias member has a range of displacement and the bias member applies substantially no force over a portion of the range of displacement.
  12. 12. An implantable system as in claim 8, wherein the bias member has a range of displacement greater than 1.0 cm.
  13. 13. An implantable system as in claim 8, wherein the bias member includes a spring.
  14. 14. An implantable system as in claim 8, further including a bushing to isolate movement of the attachment members from the vertebrae.
  15. 15. A method of reinforcing an annulus of an intervertebral disc disposed between a first vertebra and a second vertebra in an adult human spine, the method comprising the steps of:
    providing an implantable reinforcement member; and
    implanting the reinforcement member into the annulus of the intervertebral disc.
  16. 16. A method as in claim 15, further comprising the step of partially separating the adjacent vertebrae prior to the step of implantation.
  17. 17. A method as in claim 15, wherein a plurality of implantable reinforcement members are provided, and wherein the plurality of reinforcement members are implanted substantially parallel in the annulus.
  18. 18. A method as in claim 15, wherein the reinforcement member is expandable, further comprising the step of expanding the reinforcement member.
  19. 19. A method as in claim 15, further comprising the steps of:
    providing a tubular member having a curved tip and a lumen extending therethrough;
    inserting the tip of the tubular member into the annulus; and
    inserting the reinforcement member through the lumen of the tubular member and into the annulus.
  20. 20. A method as in claim 15, further comprising the steps of:
    providing one or more implantable bias devices, each having a first vertebral attachment member, a second vertebral attachment member, and a bias force member applying a bias force therebetween while permitting near normal relative motion therebetween;
    attaching the first attachment member of each implantable bias device to the first vertebra; and
    attaching the second attachment member of each implantable bias device to the second vertebra.
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US11753649 US20080255616A1 (en) 2000-04-04 2007-05-25 Devices and Methods for the Treatment of Spinal Disorders
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Cited By (307)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040073215A1 (en) * 2002-10-14 2004-04-15 Scient ' X Dynamic intervertebral connection device with controlled multidirectional deflection
US20040097931A1 (en) * 2002-10-29 2004-05-20 Steve Mitchell Interspinous process and sacrum implant and method
US20040143264A1 (en) * 2002-08-23 2004-07-22 Mcafee Paul C. Metal-backed UHMWPE rod sleeve system preserving spinal motion
US20040153071A1 (en) * 1998-10-27 2004-08-05 St. Francis Medical Technologies, Inc. Interspinous process distraction system and method with positionable wing and method
US20040167520A1 (en) * 1997-01-02 2004-08-26 St. Francis Medical Technologies, Inc. Spinous process implant with tethers
US20050075634A1 (en) * 2002-10-29 2005-04-07 Zucherman James F. Interspinous process implant with radiolucent spacer and lead-in tissue expander
US20050124991A1 (en) * 2003-12-05 2005-06-09 Tae-Ahn Jahng Method and apparatus for flexible fixation of a spine
US20050171543A1 (en) * 2003-05-02 2005-08-04 Timm Jens P. Spine stabilization systems and associated devices, assemblies and methods
US20050177156A1 (en) * 2003-05-02 2005-08-11 Timm Jens P. Surgical implant devices and systems including a sheath member
US20050177157A1 (en) * 2003-09-24 2005-08-11 N Spine, Inc. Method and apparatus for flexible fixation of a spine
US20050203514A1 (en) * 2003-09-24 2005-09-15 Tae-Ahn Jahng Adjustable spinal stabilization system
US20050216017A1 (en) * 2004-03-09 2005-09-29 Louie Fielding Spinal implant and method for restricting spinal flexion
US20050222569A1 (en) * 2003-05-02 2005-10-06 Panjabi Manohar M Dynamic spine stabilizer
US20050245930A1 (en) * 2003-05-02 2005-11-03 Timm Jens P Dynamic spine stabilizer
US20050251170A1 (en) * 2004-05-07 2005-11-10 Ethicon Endo-Surgery, Inc. Instrument for effecting anastomosis of respective tissues defining two body lumens
US20050261680A1 (en) * 2001-03-28 2005-11-24 Imperial College Innovations Ltd. Bone fixated, articulated joint load control device
US20050261768A1 (en) * 2004-05-21 2005-11-24 Trieu Hai H Interspinous spacer
US20060064166A1 (en) * 2004-09-23 2006-03-23 St. Francis Medical Technologies, Inc. Interspinous process implant including a binder and method of implantation
US20060064165A1 (en) * 2004-09-23 2006-03-23 St. Francis Medical Technologies, Inc. Interspinous process implant including a binder and method of implantation
US20060084982A1 (en) * 2004-10-20 2006-04-20 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US20060084983A1 (en) * 2004-10-20 2006-04-20 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US20060084985A1 (en) * 2004-10-20 2006-04-20 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US20060084976A1 (en) * 2004-09-30 2006-04-20 Depuy Spine, Inc. Posterior stabilization systems and methods
US20060085076A1 (en) * 2004-10-15 2006-04-20 Manoj Krishna Posterior spinal arthroplasty-development of a new posteriorly inserted artificial disc and an artificial facet joint
US20060111715A1 (en) * 2004-02-27 2006-05-25 Jackson Roger P Dynamic stabilization assemblies, tool set and method
US20060122620A1 (en) * 2004-10-20 2006-06-08 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for stabilizing the motion or adjusting the position of the spine
US20060136060A1 (en) * 2002-09-10 2006-06-22 Jean Taylor Posterior vertebral support assembly
US20060149229A1 (en) * 2004-12-30 2006-07-06 Kwak Seungkyu Daniel Artificial facet joint
US20060155279A1 (en) * 2004-10-28 2006-07-13 Axial Biotech, Inc. Apparatus and method for concave scoliosis expansion
US20060184248A1 (en) * 2005-02-17 2006-08-17 Edidin Avram A Percutaneous spinal implants and methods
US20060184247A1 (en) * 2005-02-17 2006-08-17 Edidin Avram A Percutaneous spinal implants and methods
US20060189984A1 (en) * 2005-02-22 2006-08-24 Medicinelodge, Inc. Apparatus and method for dynamic vertebral stabilization
US20060202242A1 (en) * 2005-03-09 2006-09-14 Sony Corporation Solid-state imaging device
US20060212033A1 (en) * 2005-03-03 2006-09-21 Accin Corporation Vertebral stabilization using flexible rods
US20060224159A1 (en) * 2005-03-31 2006-10-05 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US20060229612A1 (en) * 2005-03-03 2006-10-12 Accin Corporation Methods and apparatus for vertebral stabilization using sleeved springs
US20060235387A1 (en) * 2005-04-15 2006-10-19 Sdgi Holdings, Inc. Transverse process/laminar spacer
US20060241614A1 (en) * 2005-04-12 2006-10-26 Sdgi Holdings, Inc. Implants and methods for posterior dynamic stabilization of a spinal motion segment
US20060241613A1 (en) * 2005-04-12 2006-10-26 Sdgi Holdings, Inc. Implants and methods for inter-transverse process dynamic stabilization of a spinal motion segment
US20060241757A1 (en) * 2005-03-31 2006-10-26 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of manufacturing same
US20060247640A1 (en) * 2005-04-29 2006-11-02 Sdgi Holdings, Inc. Spinous process stabilization devices and methods
US20060247637A1 (en) * 2004-08-09 2006-11-02 Dennis Colleran System and method for dynamic skeletal stabilization
US20060264939A1 (en) * 2003-05-22 2006-11-23 St. Francis Medical Technologies, Inc. Interspinous process implant with slide-in distraction piece and method of implantation
US20060264940A1 (en) * 2003-09-29 2006-11-23 Stephan Hartmann Dynamic damping element for two bones
US20060265074A1 (en) * 2004-10-21 2006-11-23 Manoj Krishna Posterior spinal arthroplasty-development of a new posteriorly inserted artificial disc, a new anteriorly inserted artifical disc and an artificial facet joint
US20060265066A1 (en) * 2005-03-21 2006-11-23 St. Francis Medical Technologies, Inc. Interspinous process implant having a thread-shaped wing and method of implantation
US20060264938A1 (en) * 2005-03-21 2006-11-23 St. Francis Medical Technologies, Inc. Interspinous process implant having deployable wing and method of implantation
US20060271049A1 (en) * 2005-04-18 2006-11-30 St. Francis Medical Technologies, Inc. Interspinous process implant having deployable wings and method of implantation
US20060282080A1 (en) * 2005-06-08 2006-12-14 Accin Corporation Vertebral facet stabilizer
WO2007019894A1 (en) * 2005-06-22 2007-02-22 Tutogen Medical Gmbh Vertebral implant made from bone material for relief of a narrowed vertebral channel
US20070043356A1 (en) * 2005-07-26 2007-02-22 Timm Jens P Dynamic spine stabilization device with travel-limiting functionality
US20070043359A1 (en) * 2005-07-22 2007-02-22 Moti Altarac Systems and methods for stabilization of bone structures
US20070049934A1 (en) * 2005-02-17 2007-03-01 Edidin Avram A Percutaneous spinal implants and methods
US20070049935A1 (en) * 2005-02-17 2007-03-01 Edidin Avram A Percutaneous spinal implants and methods
US20070055246A1 (en) * 1997-01-02 2007-03-08 St. Francis Medical Technologies, Inc. Spine distraction implant and method
US20070055237A1 (en) * 2005-02-17 2007-03-08 Edidin Avram A Percutaneous spinal implants and methods
US20070093814A1 (en) * 2005-10-11 2007-04-26 Callahan Ronald Ii Dynamic spinal stabilization systems
US20070093815A1 (en) * 2005-10-11 2007-04-26 Callahan Ronald Ii Dynamic spinal stabilizer
US20070093813A1 (en) * 2005-10-11 2007-04-26 Callahan Ronald Ii Dynamic spinal stabilizer
US20070100340A1 (en) * 2005-10-27 2007-05-03 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US20070100341A1 (en) * 2004-10-20 2007-05-03 Reglos Joey C Systems and methods for stabilization of bone structures
US20070123861A1 (en) * 2005-11-10 2007-05-31 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US20070167949A1 (en) * 2004-10-20 2007-07-19 Moti Altarac Screw systems and methods for use in stabilization of bone structures
US20070168038A1 (en) * 2006-01-13 2007-07-19 Sdgi Holdings, Inc. Materials, devices and methods for treating multiple spinal regions including the interbody region
US20070167945A1 (en) * 2006-01-18 2007-07-19 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of manufacturing same
US20070173820A1 (en) * 2006-01-13 2007-07-26 Sdgi Holdings, Inc. Materials, devices, and methods for treating multiple spinal regions including the anterior region
US20070173823A1 (en) * 2006-01-18 2007-07-26 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US20070191834A1 (en) * 2006-01-27 2007-08-16 Sdgi Holdings, Inc. Artificial spinous process for the sacrum and methods of use
US20070191953A1 (en) * 2006-01-27 2007-08-16 Sdgi Holdings, Inc. Intervertebral implants and methods of use
US20070191837A1 (en) * 2006-01-27 2007-08-16 Sdgi Holdings, Inc. Interspinous devices and methods of use
US20070191838A1 (en) * 2006-01-27 2007-08-16 Sdgi Holdings, Inc. Interspinous devices and methods of use
US20070191832A1 (en) * 2006-01-27 2007-08-16 Sdgi Holdings, Inc. Vertebral rods and methods of use
US20070198014A1 (en) * 2006-02-07 2007-08-23 Sdgi Holdings, Inc. Articulating connecting member and anchor systems for spinal stabilization
US20070225710A1 (en) * 2003-09-24 2007-09-27 Tae-Ahn Jahng Spinal stabilization device
US20070225810A1 (en) * 2006-03-23 2007-09-27 Dennis Colleran Flexible cage spinal implant
US20070225706A1 (en) * 2005-02-17 2007-09-27 Clark Janna G Percutaneous spinal implants and methods
US20070233076A1 (en) * 2006-03-31 2007-10-04 Sdgi Holdings, Inc. Methods and instruments for delivering interspinous process spacers
US20070233074A1 (en) * 2006-03-16 2007-10-04 Sdgi Holdings, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US20070233094A1 (en) * 2006-03-29 2007-10-04 Dennis Colleran Dynamic motion spinal stabilization system
US20070233068A1 (en) * 2006-02-22 2007-10-04 Sdgi Holdings, Inc. Intervertebral prosthetic assembly for spinal stabilization and method of implanting same
US20070233095A1 (en) * 2004-10-07 2007-10-04 Schlaepfer Fridolin J Device for dynamic stabilization of bones or bone fragments
US20070239159A1 (en) * 2005-07-22 2007-10-11 Vertiflex, Inc. Systems and methods for stabilization of bone structures
US20070265623A1 (en) * 2005-02-17 2007-11-15 Malandain Hugues F Percutaneous Spinal Implants and Methods
US20070270823A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Multi-chamber expandable interspinous process brace
US20070270825A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Expandable interspinous process implant and method of installing same
US20070270834A1 (en) * 2006-05-04 2007-11-22 Sdgi Holdings, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US20070270828A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Interspinous process brace
US20070270824A1 (en) * 2006-04-28 2007-11-22 Warsaw Orthopedic, Inc. Interspinous process brace
US20070270814A1 (en) * 2006-04-20 2007-11-22 Sdgi Holdings, Inc. Vertebral stabilizer
US20070270959A1 (en) * 2006-04-18 2007-11-22 Sdgi Holdings, Inc. Arthroplasty device
US20070270826A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Interosteotic implant
US20070270829A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Molding device for an expandable interspinous process implant
US20070276368A1 (en) * 2006-05-23 2007-11-29 Sdgi Holdings, Inc. Systems and methods for adjusting properties of a spinal implant
US20070276373A1 (en) * 2005-02-17 2007-11-29 Malandain Hugues F Percutaneous Spinal Implants and Methods
US20070276500A1 (en) * 2004-09-23 2007-11-29 St. Francis Medical Technologies, Inc. Interspinous process implant including a binder, binder aligner and method of implantation
US20070276372A1 (en) * 2005-02-17 2007-11-29 Malandain Hugues F Percutaneous Spinal Implants and Methods
US20070276370A1 (en) * 2004-10-20 2007-11-29 Vertiflex, Inc. Minimally invasive tooling for delivery of interspinous spacer
US20070276380A1 (en) * 2003-09-24 2007-11-29 Tae-Ahn Jahng Spinal stabilization device
US20070276496A1 (en) * 2006-05-23 2007-11-29 Sdgi Holdings, Inc. Surgical spacer with shape control
US20070276369A1 (en) * 2006-05-26 2007-11-29 Sdgi Holdings, Inc. In vivo-customizable implant
US20070276493A1 (en) * 2005-02-17 2007-11-29 Malandain Hugues F Percutaneous spinal implants and methods
US20070282340A1 (en) * 2005-02-17 2007-12-06 Malandain Hugues F Percutaneous spinal implants and methods
US20070282442A1 (en) * 2005-02-17 2007-12-06 Malandain Hugues F Percutaneous spinal implants and methods
US20070288094A1 (en) * 2006-06-08 2007-12-13 Manoj Krishna System and method for lumbar arthroplasty
US20070288012A1 (en) * 2006-04-21 2007-12-13 Dennis Colleran Dynamic motion spinal stabilization system and device
US20070288009A1 (en) * 2006-06-08 2007-12-13 Steven Brown Dynamic spinal stabilization device
US20080009866A1 (en) * 2004-03-09 2008-01-10 Todd Alamin Methods and systems for constraint of spinous processes with attachment
US20080021468A1 (en) * 2002-10-29 2008-01-24 Zucherman James F Interspinous process implants and methods of use
US20080021460A1 (en) * 2006-07-20 2008-01-24 Warsaw Orthopedic Inc. Apparatus for insertion between anatomical structures and a procedure utilizing same
US20080021471A1 (en) * 2003-02-12 2008-01-24 Kyphon Inc. System and Method for Immobilizing Adjacent Spinous Processes
US20080027552A1 (en) * 1997-01-02 2008-01-31 Zucherman James F Spine distraction implant and method
US20080027553A1 (en) * 1997-01-02 2008-01-31 Zucherman James F Spine distraction implant and method
US20080027433A1 (en) * 2005-02-17 2008-01-31 Kohm Andrew C Percutaneous spinal implants and methods
US20080033435A1 (en) * 2001-12-07 2008-02-07 Armin Studer Damping element and device for stabilization of adjacent vertebral bodies
US20080039944A1 (en) * 2005-02-17 2008-02-14 Malandain Hugues F Percutaneous Spinal Implants and Methods
US20080051894A1 (en) * 2005-02-17 2008-02-28 Malandain Hugues F Percutaneous spinal implants and methods
US20080051893A1 (en) * 2005-02-17 2008-02-28 Malandain Hugues F Percutaneous spinal implants and methods
US20080065219A1 (en) * 2006-09-08 2008-03-13 Justin Dye Offset radius lordosis
US20080065078A1 (en) * 1999-12-01 2008-03-13 Henry Graf Intervertebral stabilising device
US20080071376A1 (en) * 2005-02-17 2008-03-20 Kohm Andrew C Percutaneous spinal implants and methods
US20080071378A1 (en) * 1997-01-02 2008-03-20 Zucherman James F Spine distraction implant and method
US20080077241A1 (en) * 2006-09-22 2008-03-27 Linh Nguyen Removable rasp/trial member insert, kit and method of use
US20080091213A1 (en) * 2004-02-27 2008-04-17 Jackson Roger P Tool system for dynamic spinal implants
WO2008051801A2 (en) 2006-10-19 2008-05-02 Simpirica Spine, Inc. Structures and methods for constraining spinal processes with single connector
US20080114456A1 (en) * 2006-11-15 2008-05-15 Warsaw Orthopedic, Inc. Spinal implant system
US20080114357A1 (en) * 2006-11-15 2008-05-15 Warsaw Orthopedic, Inc. Inter-transverse process spacer device and method for use in correcting a spinal deformity
US20080114455A1 (en) * 2006-11-15 2008-05-15 Warsaw Orthopedic, Inc. Rotating Interspinous Process Devices and Methods of Use
US20080132952A1 (en) * 2005-02-17 2008-06-05 Malandain Hugues F Percutaneous spinal implants and methods
US20080161919A1 (en) * 2006-10-03 2008-07-03 Warsaw Orthopedic, Inc. Dynamic Devices and Methods for Stabilizing Vertebral Members
US20080161920A1 (en) * 2006-10-03 2008-07-03 Warsaw Orthopedic, Inc. Dynamizing Interbody Implant and Methods for Stabilizing Vertebral Members
US20080172090A1 (en) * 2007-01-12 2008-07-17 Warsaw Orthopedic, Inc. Spinal Prosthesis Systems
US20080172057A1 (en) * 1997-01-02 2008-07-17 Zucherman James F Spine distraction implant and method
US20080177391A1 (en) * 2006-10-24 2008-07-24 St. Francis Medical Technologies, Inc. Systems and Methods for In Situ Assembly of an Interspinous Process Distraction Implant
US20080177298A1 (en) * 2006-10-24 2008-07-24 St. Francis Medical Technologies, Inc. Tensioner Tool and Method for Implanting an Interspinous Process Implant Including a Binder
US20080177264A1 (en) * 2006-10-19 2008-07-24 Simpirica Spine, Inc. Methods and systems for laterally stabilized constraint of spinous processes
US20080177333A1 (en) * 2006-10-24 2008-07-24 Warsaw Orthopedic, Inc. Adjustable jacking implant
US20080195154A1 (en) * 2006-06-08 2008-08-14 Disc Motion Technologies, Inc. Dynamic spinal stabilization device
US20080234824A1 (en) * 2007-02-06 2008-09-25 Youssef Jim A Interspinous dynamic stabilization implant and method of implanting
US20080262549A1 (en) * 2006-10-19 2008-10-23 Simpirica Spine, Inc. Methods and systems for deploying spinous process constraints
US20080275560A1 (en) * 2007-05-01 2008-11-06 Exploramed Nc4, Inc. Femoral and tibial base components
US20080275559A1 (en) * 2007-05-01 2008-11-06 Exploramed Nc4, Inc. Adjustable absorber designs for implantable device
US20080275567A1 (en) * 2007-05-01 2008-11-06 Exploramed Nc4, Inc. Extra-Articular Implantable Mechanical Energy Absorbing Systems
US20080275561A1 (en) * 2007-05-01 2008-11-06 Exploramed Nc4, Inc. Extra-articular implantable mechanical energy absorbing systems and implantation method
US20080281361A1 (en) * 2007-05-10 2008-11-13 Shannon Marlece Vittur Posterior stabilization and spinous process systems and methods
US20080288078A1 (en) * 2005-02-17 2008-11-20 Kohm Andrew C Percutaneous spinal implants and methods
US20080287997A1 (en) * 2004-10-20 2008-11-20 Moti Altarac Interspinous spacer
EP1994900A1 (en) * 2007-05-22 2008-11-26 Flexismed SA Interspinous vertebral implant
US20080294199A1 (en) * 2007-05-25 2008-11-27 Andrew Kohm Spinous process implants and methods of using the same
US20080294263A1 (en) * 2004-10-20 2008-11-27 Moti Altarac Interspinous spacer
US20080319487A1 (en) * 2007-06-22 2008-12-25 Simpirica Spine, Inc. Methods and Devices for Controlled Flexion Restriction of Spinal Segments
US20090030523A1 (en) * 2001-08-08 2009-01-29 Jean Taylor Veretebra Stabilizing Assembly
US20090062915A1 (en) * 2007-08-27 2009-03-05 Andrew Kohm Spinous-process implants and methods of using the same
US20090088782A1 (en) * 2007-09-28 2009-04-02 Missoum Moumene Flexible Spinal Rod With Elastomeric Jacket
US20090125030A1 (en) * 2006-10-18 2009-05-14 Shawn Tebbe Dilator
US20090163955A1 (en) * 2007-12-19 2009-06-25 Missoum Moumene Polymeric Pedicle Rods and Methods of Manufacturing
US20090198245A1 (en) * 2008-02-04 2009-08-06 Phan Christopher U Tools and methods for insertion and removal of medical implants
US20090198337A1 (en) * 2008-02-04 2009-08-06 Phan Christopher U Medical implants and methods
US20090222043A1 (en) * 2004-10-20 2009-09-03 Moti Altarac Interspinous process spacer instrument system with deployment indicator
US20090227990A1 (en) * 2006-09-07 2009-09-10 Stoklund Ole Intercostal spacer device and method for use in correcting a spinal deformity
US20090240283A1 (en) * 2008-03-18 2009-09-24 Warsaw Orthopedic, Inc. Implants and methods for inter-spinous process dynamic stabilization of a spinal motion segment
US20090264932A1 (en) * 2006-10-19 2009-10-22 Simpirica Spine, Inc. Methods and systems for constraint of multiple spine segments
US20090275982A1 (en) * 2006-04-13 2009-11-05 Jean Taylor Device for treating vertebrae, including an interspinous implant
WO2009146428A1 (en) * 2008-05-30 2009-12-03 Synthes Usa, Llc Balloon-assisted annulus repair
WO2009149414A1 (en) 2008-06-06 2009-12-10 Simpirica Spine, Inc. Methods and apparatus for locking a band
WO2009149407A1 (en) 2008-06-06 2009-12-10 Simpirica Spine, Inc. Methods and apparatus for locking a band
US20090326584A1 (en) * 2008-06-27 2009-12-31 Michael Andrew Slivka Spinal Dynamic Stabilization Rods Having Interior Bumpers
US20090326583A1 (en) * 2008-06-25 2009-12-31 Missoum Moumene Posterior Dynamic Stabilization System With Flexible Ligament
US20100004744A1 (en) * 1997-01-02 2010-01-07 Kyphon Sarl Interspinous process distraction system and method with positionable wing and method
US20100030549A1 (en) * 2008-07-31 2010-02-04 Lee Michael M Mobile device having human language translation capability with positional feedback
US20100030269A1 (en) * 2006-09-07 2010-02-04 Jean Taylor Interspinous spinal prosthesis
US20100036424A1 (en) * 2007-06-22 2010-02-11 Simpirica Spine, Inc. Methods and systems for increasing the bending stiffness and constraining the spreading of a spinal segment
US20100070038A1 (en) * 2006-11-08 2010-03-18 Jean Taylor Interspinous implant
US20100069964A1 (en) * 2006-06-28 2010-03-18 Beat Lechmann Dynamic fixation system
US7691130B2 (en) 2006-01-27 2010-04-06 Warsaw Orthopedic, Inc. Spinal implants including a sensor and methods of use
US20100087862A1 (en) * 2008-10-08 2010-04-08 Lutz Biedermann Elongated implant device and bone stabilization device including the same
US7695513B2 (en) 2003-05-22 2010-04-13 Kyphon Sarl Distractible interspinous process implant and method of implantation
US20100094344A1 (en) * 2008-10-14 2010-04-15 Kyphon Sarl Pedicle-Based Posterior Stabilization Members and Methods of Use
US20100106252A1 (en) * 2008-10-29 2010-04-29 Kohm Andrew C Spinal implants having multiple movable members
US20100114166A1 (en) * 2008-11-05 2010-05-06 Andrew Kohm Extension limiting devices and methods of use for the spine
US20100137996A1 (en) * 2007-05-01 2010-06-03 Moximed, Inc. Femoral and tibial base components
US20100145449A1 (en) * 2007-05-01 2010-06-10 Moximed, Inc. Adjustable absorber designs for implantable device
US20100152776A1 (en) * 2008-12-17 2010-06-17 Synthes Usa, Llc Posterior spine dynamic stabilizer
US20100185241A1 (en) * 2009-01-16 2010-07-22 Malandain Hugues F Adjustable surgical cables and methods for treating spinal stenosis
US7766940B2 (en) 2004-12-30 2010-08-03 Depuy Spine, Inc. Posterior stabilization system
US7766915B2 (en) 2004-02-27 2010-08-03 Jackson Roger P Dynamic fixation assemblies with inner core and outer coil-like member
WO2010088621A1 (en) 2009-02-02 2010-08-05 Simpirica Spine, Inc. Sacral tether anchor and methods of use
US20100211104A1 (en) * 2009-02-13 2010-08-19 Missoum Moumene Dual Spring Posterior Dynamic Stabilization Device With Elongation Limiting Elastomers
US20100234894A1 (en) * 2009-03-10 2010-09-16 Simpirica Spine, Inc. Surgical tether apparatus and methods of use
WO2010104975A1 (en) 2009-03-10 2010-09-16 Simpirica Spine, Inc. Surgical tether apparatus and methods of use
US7803190B2 (en) 2002-10-29 2010-09-28 Kyphon SÀRL Interspinous process apparatus and method with a selectably expandable spacer
US20100262243A1 (en) * 1997-01-02 2010-10-14 Kyphon Sarl Spine distraction implant
WO2010121256A1 (en) 2009-04-17 2010-10-21 Simpirica Spine, Inc. Structures and methods for constraining spinal processes with single connector
US20100274287A1 (en) * 2009-04-24 2010-10-28 Warsaw Orthopedic, Inc. Flexible Articulating Spinal Rod
US20100286701A1 (en) * 2009-05-08 2010-11-11 Kyphon Sarl Distraction tool for distracting an interspinous space
US7846186B2 (en) 2005-06-28 2010-12-07 Kyphon SÀRL Equipment for surgical treatment of two vertebrae
US20100312277A1 (en) * 2009-06-05 2010-12-09 Kyphon Sarl Multi-level interspinous implants and methods of use
US20100318130A1 (en) * 2007-12-15 2010-12-16 Parlato Brian D Flexible rod assembly for spinal fixation
US20100318127A1 (en) * 2009-06-12 2010-12-16 Kyphon Sarl Interspinous implant and methods of use
US7854752B2 (en) 2004-08-09 2010-12-21 Theken Spine, Llc System and method for dynamic skeletal stabilization
US20100331886A1 (en) * 2009-06-25 2010-12-30 Jonathan Fanger Posterior Dynamic Stabilization Device Having A Mobile Anchor
US7862590B2 (en) 2005-04-08 2011-01-04 Warsaw Orthopedic, Inc. Interspinous process spacer
US20110040331A1 (en) * 2009-05-20 2011-02-17 Jose Fernandez Posterior stabilizer
US7901437B2 (en) 2007-01-26 2011-03-08 Jackson Roger P Dynamic stabilization member with molded connection
US20110077686A1 (en) * 2009-09-29 2011-03-31 Kyphon Sarl Interspinous process implant having a compliant spacer
US20110093079A1 (en) * 2009-10-20 2011-04-21 Slone Clinton N Extra-articular implantable mechanical energy absorbing assemblies having a tension member, and methods
FR2951365A1 (en) * 2009-10-20 2011-04-22 Henry Graf Extra-discal intervertebral stabilization assembly for arthrodesis, has spring plate for connecting rings of connection unit, where plate is bent for offering controlled resistance to connection, during connection of adjacent screws
US20110098745A1 (en) * 2009-10-28 2011-04-28 Kyphon Sarl Interspinous process implant and method of implantation
US20110106160A1 (en) * 2004-10-20 2011-05-05 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US7951170B2 (en) 2007-05-31 2011-05-31 Jackson Roger P Dynamic stabilization connecting member with pre-tensioned solid core
US7955392B2 (en) 2006-12-14 2011-06-07 Warsaw Orthopedic, Inc. Interspinous process devices and methods
US7976549B2 (en) 2006-03-23 2011-07-12 Theken Spine, Llc Instruments for delivering spinal implants
US20110172720A1 (en) * 2010-01-13 2011-07-14 Kyphon Sarl Articulating interspinous process clamp
US20110172596A1 (en) * 2010-01-13 2011-07-14 Kyphon Sarl Interspinous process spacer diagnostic balloon catheter and methods of use
US20110172708A1 (en) * 2007-06-22 2011-07-14 Simpirica Spine, Inc. Methods and systems for increasing the bending stiffness of a spinal segment with elongation limit
US7993342B2 (en) 2005-02-17 2011-08-09 Kyphon Sarl Percutaneous spinal implants and methods
US7998174B2 (en) 2005-02-17 2011-08-16 Kyphon Sarl Percutaneous spinal implants and methods
US20110213301A1 (en) * 2010-02-26 2011-09-01 Kyphon SÀRL Interspinous process spacer diagnostic parallel balloon catheter and methods of use
US8012177B2 (en) 2007-02-12 2011-09-06 Jackson Roger P Dynamic stabilization assembly with frusto-conical connection
US8012207B2 (en) 2004-10-20 2011-09-06 Vertiflex, Inc. Systems and methods for posterior dynamic stabilization of the spine
US20110230914A1 (en) * 2007-08-07 2011-09-22 Synthes (U.S.A.) Dynamic cable system
US8025680B2 (en) 2004-10-20 2011-09-27 Exactech, Inc. Systems and methods for posterior dynamic stabilization of the spine
US20110238119A1 (en) * 2010-03-24 2011-09-29 Missoum Moumene Composite Material Posterior Dynamic Stabilization Spring Rod
US8029548B2 (en) 2008-05-05 2011-10-04 Warsaw Orthopedic, Inc. Flexible spinal stabilization element and system
US8048118B2 (en) 2006-04-28 2011-11-01 Warsaw Orthopedic, Inc. Adjustable interspinous process brace
US8048117B2 (en) 2003-05-22 2011-11-01 Kyphon Sarl Interspinous process implant and method of implantation
US8057513B2 (en) 2005-02-17 2011-11-15 Kyphon Sarl Percutaneous spinal implants and methods
US8070778B2 (en) 2003-05-22 2011-12-06 Kyphon Sarl Interspinous process implant with slide-in distraction piece and method of implantation
US8092502B2 (en) 2003-04-09 2012-01-10 Jackson Roger P Polyaxial bone screw with uploaded threaded shank and method of assembly and use
US8092500B2 (en) 2007-05-01 2012-01-10 Jackson Roger P Dynamic stabilization connecting member with floating core, compression spacer and over-mold
US8092496B2 (en) 2004-09-30 2012-01-10 Depuy Spine, Inc. Methods and devices for posterior stabilization
US8096994B2 (en) 2005-02-17 2012-01-17 Kyphon Sarl Percutaneous spinal implants and methods
US8096996B2 (en) 2007-03-20 2012-01-17 Exactech, Inc. Rod reducer
US8100943B2 (en) 2005-02-17 2012-01-24 Kyphon Sarl Percutaneous spinal implants and methods
US8100915B2 (en) 2004-02-27 2012-01-24 Jackson Roger P Orthopedic implant rod reduction tool set and method
US8105368B2 (en) 2005-09-30 2012-01-31 Jackson Roger P Dynamic stabilization connecting member with slitted core and outer sleeve
US8109973B2 (en) 2005-10-31 2012-02-07 Stryker Spine Method for dynamic vertebral stabilization
US8114132B2 (en) 2010-01-13 2012-02-14 Kyphon Sarl Dynamic interspinous process device
US8118844B2 (en) 2006-04-24 2012-02-21 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US8118840B2 (en) 2009-02-27 2012-02-21 Warsaw Orthopedic, Inc. Vertebral rod and related method of manufacture
US8123782B2 (en) 2004-10-20 2012-02-28 Vertiflex, Inc. Interspinous spacer
US8123805B2 (en) 2007-05-01 2012-02-28 Moximed, Inc. Adjustable absorber designs for implantable device
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8152837B2 (en) 2004-10-20 2012-04-10 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8152810B2 (en) 2004-11-23 2012-04-10 Jackson Roger P Spinal fixation tool set and method
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US20120109201A1 (en) * 2010-04-30 2012-05-03 Neuraxis Llc Intersegmental motion preservation system for use in the spine and methods for use thereof
US20120109202A1 (en) * 2010-04-30 2012-05-03 Neuraxis Llc Intersegmental motion preservation system for use in the spine and methods for use thereof
US8187305B2 (en) 2008-06-06 2012-05-29 Simpirica Spine, Inc. Methods and apparatus for deploying spinous process constraints
US8252028B2 (en) 2007-12-19 2012-08-28 Depuy Spine, Inc. Posterior dynamic stabilization device
US8292922B2 (en) 2004-10-20 2012-10-23 Vertiflex, Inc. Interspinous spacer
US8292926B2 (en) 2005-09-30 2012-10-23 Jackson Roger P Dynamic stabilization connecting member with elastic core and outer sleeve
US8317864B2 (en) 2004-10-20 2012-11-27 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8353932B2 (en) 2005-09-30 2013-01-15 Jackson Roger P Polyaxial bone anchor assembly with one-piece closure, pressure insert and plastic elongate member
US8366745B2 (en) 2007-05-01 2013-02-05 Jackson Roger P Dynamic stabilization assembly having pre-compressed spacers with differential displacements
US8409282B2 (en) 2004-10-20 2013-04-02 Vertiflex, Inc. Systems and methods for posterior dynamic stabilization of the spine
US8425559B2 (en) 2004-10-20 2013-04-23 Vertiflex, Inc. Systems and methods for posterior dynamic stabilization of the spine
US8444681B2 (en) 2009-06-15 2013-05-21 Roger P. Jackson Polyaxial bone anchor with pop-on shank, friction fit retainer and winged insert
US8460319B2 (en) 2010-01-11 2013-06-11 Anulex Technologies, Inc. Intervertebral disc annulus repair system and method
US8475498B2 (en) 2007-01-18 2013-07-02 Roger P. Jackson Dynamic stabilization connecting member with cord connection
US8523865B2 (en) 2005-07-22 2013-09-03 Exactech, Inc. Tissue splitter
US8545538B2 (en) 2005-12-19 2013-10-01 M. Samy Abdou Devices and methods for inter-vertebral orthopedic device placement
US8556977B2 (en) 1999-10-20 2013-10-15 Anulex Technologies, Inc. Tissue anchoring system and method
US8556938B2 (en) 2009-06-15 2013-10-15 Roger P. Jackson Polyaxial bone anchor with non-pivotable retainer and pop-on shank, some with friction fit
US8562650B2 (en) 2011-03-01 2013-10-22 Warsaw Orthopedic, Inc. Percutaneous spinous process fusion plate assembly and method
US8591549B2 (en) 2011-04-08 2013-11-26 Warsaw Orthopedic, Inc. Variable durometer lumbar-sacral implant
US8591515B2 (en) 2004-11-23 2013-11-26 Roger P. Jackson Spinal fixation tool set and method
US8591548B2 (en) 2011-03-31 2013-11-26 Warsaw Orthopedic, Inc. Spinous process fusion plate assembly
US8597362B2 (en) 2009-08-27 2013-12-03 Cotera, Inc. Method and apparatus for force redistribution in articular joints
US8613747B2 (en) 2004-10-20 2013-12-24 Vertiflex, Inc. Spacer insertion instrument
US8668719B2 (en) 2009-03-30 2014-03-11 Simpirica Spine, Inc. Methods and apparatus for improving shear loading capacity of a spinal segment
US8696710B2 (en) 2010-10-06 2014-04-15 Simpirica Spine, Inc. Device and accessories for limiting flexion
US8709090B2 (en) 2007-05-01 2014-04-29 Moximed, Inc. Adjustable absorber designs for implantable device
US8740948B2 (en) 2009-12-15 2014-06-03 Vertiflex, Inc. Spinal spacer for cervical and other vertebra, and associated systems and methods
US8814908B2 (en) 2010-07-26 2014-08-26 Warsaw Orthopedic, Inc. Injectable flexible interspinous process device system
US8814913B2 (en) 2002-09-06 2014-08-26 Roger P Jackson Helical guide and advancement flange with break-off extensions
US8840646B2 (en) 2007-05-10 2014-09-23 Warsaw Orthopedic, Inc. Spinous process implants and methods
US8845649B2 (en) 2004-09-24 2014-09-30 Roger P. Jackson Spinal fixation tool set and method for rod reduction and fastener insertion
US8845724B2 (en) 2009-08-27 2014-09-30 Cotera, Inc. Method and apparatus for altering biomechanics of the articular joints
US8864828B2 (en) 2004-10-20 2014-10-21 Vertiflex, Inc. Interspinous spacer
US8894714B2 (en) 2007-05-01 2014-11-25 Moximed, Inc. Unlinked implantable knee unloading device
US8911477B2 (en) 2007-10-23 2014-12-16 Roger P. Jackson Dynamic stabilization member with end plate support and cable core extension
US8979904B2 (en) 2007-05-01 2015-03-17 Roger P Jackson Connecting member with tensioned cord, low profile rigid sleeve and spacer with torsion control
US9011494B2 (en) 2009-09-24 2015-04-21 Warsaw Orthopedic, Inc. Composite vertebral rod system and methods of use
US9044270B2 (en) 2011-03-29 2015-06-02 Moximed, Inc. Apparatus for controlling a load on a hip joint
US9050139B2 (en) 2004-02-27 2015-06-09 Roger P. Jackson Orthopedic implant rod reduction tool set and method
US9095442B2 (en) 1999-10-20 2015-08-04 Krt Investors, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US9107706B2 (en) 2009-03-10 2015-08-18 Simpirica Spine, Inc. Surgical tether apparatus and methods of use
US9114025B2 (en) 1999-10-20 2015-08-25 Krt Investors, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US9119680B2 (en) 2004-10-20 2015-09-01 Vertiflex, Inc. Interspinous spacer
US9161783B2 (en) 2004-10-20 2015-10-20 Vertiflex, Inc. Interspinous spacer
US9216041B2 (en) 2009-06-15 2015-12-22 Roger P. Jackson Spinal connecting members with tensioned cords and rigid sleeves for engaging compression inserts
US9259322B2 (en) * 2013-03-11 2016-02-16 Embark Enterprises, Inc. Canine internal stifle stabilization (CISS) system
US9282996B2 (en) * 2013-03-13 2016-03-15 Moximed, Inc. Extra-articular implantable mechanical energy absorbing assemblies
US9393055B2 (en) 2004-10-20 2016-07-19 Vertiflex, Inc. Spacer insertion instrument
US9398957B2 (en) 2007-05-01 2016-07-26 Moximed, Inc. Femoral and tibial bases
US9414863B2 (en) 2005-02-22 2016-08-16 Roger P. Jackson Polyaxial bone screw with spherical capture, compression insert and alignment and retention structures
US9451989B2 (en) 2007-01-18 2016-09-27 Roger P Jackson Dynamic stabilization members with elastic and inelastic sections
US9468466B1 (en) 2012-08-24 2016-10-18 Cotera, Inc. Method and apparatus for altering biomechanics of the spine
US9480517B2 (en) 2009-06-15 2016-11-01 Roger P. Jackson Polyaxial bone anchor with pop-on shank, shank, friction fit retainer, winged insert and low profile edge lock
KR20170022740A (en) 2015-08-21 2017-03-02 (주)나노테크 Apparatus for collecting waste heat
US9668868B2 (en) 2009-08-27 2017-06-06 Cotera, Inc. Apparatus and methods for treatment of patellofemoral conditions
US9675303B2 (en) 2013-03-15 2017-06-13 Vertiflex, Inc. Visualization systems, instruments and methods of using the same in spinal decompression procedures
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
US9743957B2 (en) 2004-11-10 2017-08-29 Roger P. Jackson Polyaxial bone screw with shank articulation pressure insert and method
US9861408B2 (en) 2009-08-27 2018-01-09 The Foundry, Llc Method and apparatus for treating canine cruciate ligament disease
US9907574B2 (en) 2009-06-15 2018-03-06 Roger P. Jackson Polyaxial bone anchors with pop-on shank, friction fit fully restrained retainer, insert and tool receiving features
US9980753B2 (en) 2009-06-15 2018-05-29 Roger P Jackson pivotal anchor with snap-in-place insert having rotation blocking extensions

Families Citing this family (367)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998020939A3 (en) 1996-11-15 1998-09-03 Advanced Bio Surfaces Inc Biomaterial system for in situ tissue repair
US20070038231A1 (en) * 1999-05-28 2007-02-15 Ferree Bret A Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US7273497B2 (en) 1999-05-28 2007-09-25 Anova Corp. Methods for treating a defect in the annulus fibrosis
US20060247665A1 (en) 1999-05-28 2006-11-02 Ferree Bret A Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US7553329B2 (en) 1999-08-18 2009-06-30 Intrinsic Therapeutics, Inc. Stabilized intervertebral disc barrier
US7717961B2 (en) 1999-08-18 2010-05-18 Intrinsic Therapeutics, Inc. Apparatus delivery in an intervertebral disc
US6508839B1 (en) 1999-08-18 2003-01-21 Intrinsic Orthopedics, Inc. Devices and methods of vertebral disc augmentation
US20040024465A1 (en) * 1999-08-18 2004-02-05 Gregory Lambrecht Devices and method for augmenting a vertebral disc
EP1624832A4 (en) 1999-08-18 2008-12-24 Intrinsic Therapeutics Inc Devices and method for augmenting a vertebral disc nucleus
WO2002054978A3 (en) * 1999-08-18 2002-11-07 Intrinsic Therapeutics, Inc. Devices and method for nucleus pulposus augmentation and retention
US7998213B2 (en) 1999-08-18 2011-08-16 Intrinsic Therapeutics, Inc. Intervertebral disc herniation repair
US7220281B2 (en) 1999-08-18 2007-05-22 Intrinsic Therapeutics, Inc. Implant for reinforcing and annulus fibrosis
US6821276B2 (en) * 1999-08-18 2004-11-23 Intrinsic Therapeutics, Inc. Intervertebral diagnostic and manipulation device
US6964674B1 (en) * 1999-09-20 2005-11-15 Nuvasive, Inc. Annulotomy closure device
US20040172019A1 (en) * 1999-10-08 2004-09-02 Ferree Bret A. Reinforcers for artificial disc replacement methods and apparatus
US6592625B2 (en) * 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US6830570B1 (en) * 1999-10-21 2004-12-14 Sdgi Holdings, Inc. Devices and techniques for a posterior lateral disc space approach
US7641657B2 (en) 2003-06-10 2010-01-05 Trans1, Inc. Method and apparatus for providing posterior or anterior trans-sacral access to spinal vertebrae
US6899716B2 (en) * 2000-02-16 2005-05-31 Trans1, Inc. Method and apparatus for spinal augmentation
US6558386B1 (en) 2000-02-16 2003-05-06 Trans1 Inc. Axial spinal implant and method and apparatus for implanting an axial spinal implant within the vertebrae of the spine
US6790210B1 (en) 2000-02-16 2004-09-14 Trans1, Inc. Methods and apparatus for forming curved axial bores through spinal vertebrae
US7727263B2 (en) 2000-02-16 2010-06-01 Trans1, Inc. Articulating spinal implant
DE60321720D1 (en) 2000-02-16 2008-07-31 Trans1 Inc Apparatus for wirbelsäulendistraktion and fusion
US6575979B1 (en) 2000-02-16 2003-06-10 Axiamed, Inc. Method and apparatus for providing posterior or anterior trans-sacral access to spinal vertebrae
US6558390B2 (en) 2000-02-16 2003-05-06 Axiamed, Inc. Methods and apparatus for performing therapeutic procedures in the spine
US7776042B2 (en) * 2002-12-03 2010-08-17 Trans1 Inc. Methods and apparatus for provision of therapy to adjacent motion segments
US6740093B2 (en) 2000-02-28 2004-05-25 Stephen Hochschuler Method and apparatus for treating a vertebral body
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
FR2808995B1 (en) 2000-05-18 2003-02-21 Aesculap Sa The intersomatic cage has unified grafts
US20100168751A1 (en) * 2002-03-19 2010-07-01 Anderson D Greg Method, Implant & Instruments for Percutaneous Expansion of the Spinal Canal
US9044279B2 (en) * 2002-03-19 2015-06-02 Innovative Surgical Designs, Inc. Device and method for expanding the spinal canal with spinal column stabilization and spinal deformity correction
US7166107B2 (en) * 2000-09-11 2007-01-23 D. Greg Anderson Percutaneous technique and implant for expanding the spinal canal
US6358254B1 (en) 2000-09-11 2002-03-19 D. Greg Anderson Method and implant for expanding a spinal canal
US6579291B1 (en) 2000-10-10 2003-06-17 Spinalabs, Llc Devices and methods for the treatment of spinal disorders
US20050080486A1 (en) 2000-11-29 2005-04-14 Fallin T. Wade Facet joint replacement
US6579319B2 (en) 2000-11-29 2003-06-17 Medicinelodge, Inc. Facet joint replacement
US6969610B2 (en) * 2001-01-12 2005-11-29 University Of Rochester Methods of modifying cell structure and remodeling tissue
US6419703B1 (en) * 2001-03-01 2002-07-16 T. Wade Fallin Prosthesis for the replacement of a posterior element of a vertebra
US7090698B2 (en) * 2001-03-02 2006-08-15 Facet Solutions Method and apparatus for spine joint replacement
US6595998B2 (en) 2001-03-08 2003-07-22 Spinewave, Inc. Tissue distraction device
US6887243B2 (en) 2001-03-30 2005-05-03 Triage Medical, Inc. Method and apparatus for bone fixation with secondary compression
US6632235B2 (en) 2001-04-19 2003-10-14 Synthes (U.S.A.) Inflatable device and method for reducing fractures in bone and in treating the spine
FR2824261B1 (en) * 2001-05-04 2004-05-28 Ldr Medical intervertebral disc prosthesis and method and implementation tools
FR2827156B1 (en) * 2001-07-13 2003-11-14 Ldr Medical A spinal cage modular fixture with
FR2827498B1 (en) * 2001-07-18 2004-05-14 Frederic Fortin flexible vertebral connecting device consists of elements which overcomes a deficiency of the spine
US6736815B2 (en) * 2001-09-06 2004-05-18 Core Medical, Inc. Apparatus and methods for treating spinal discs
EP1448089A4 (en) 2001-11-01 2008-06-04 Spine Wave Inc Devices and methods for the restoration of a spinal disc
US7799833B2 (en) 2001-11-01 2010-09-21 Spine Wave, Inc. System and method for the pretreatment of the endplates of an intervertebral disc
US9480503B2 (en) * 2002-01-03 2016-11-01 Rohit Khanna Universal laminoplasty implant
DE60207893T2 (en) 2002-03-14 2006-08-17 Yeung, Jeffrey E., San Jose Suture anchors and adaptation device
US6824278B2 (en) * 2002-03-15 2004-11-30 Memx, Inc. Self-shadowing MEM structures
US7682375B2 (en) * 2002-05-08 2010-03-23 Stephen Ritland Dynamic fixation device and method of use
US20030220643A1 (en) * 2002-05-24 2003-11-27 Ferree Bret A. Devices to prevent spinal extension
US6793678B2 (en) 2002-06-27 2004-09-21 Depuy Acromed, Inc. Prosthetic intervertebral motion disc having dampening
ES2336551T3 (en) 2002-07-19 2010-04-14 Interventional Spine, Inc. Device for fixing the spine.
FR2843538B1 (en) * 2002-08-13 2005-08-12 Frederic Fortin Distraction device and adjustable damping to the growth of the spine
US7052497B2 (en) * 2002-08-14 2006-05-30 Sdgi Holdings, Inc. Techniques for spinal surgery and attaching constructs to vertebral elements
US8926672B2 (en) 2004-11-10 2015-01-06 Roger P. Jackson Splay control closure for open bone anchor
US8876868B2 (en) 2002-09-06 2014-11-04 Roger P. Jackson Helical guide and advancement flange with radially loaded lip
FR2844180B1 (en) * 2002-09-11 2005-08-05 Spinevision Connecting element for the dynamic stabilization of a spinal fixation system and spinal fixation system comprising such element
DE60331955D1 (en) * 2002-09-24 2010-05-12 Bogomir Gorensek Stabilizing device for intervertebral discs and methods for
JP2007521843A (en) 2003-05-15 2007-08-09 バイオメリクス コーポレーション Reticulated elastomeric matrix, their preparation and use in implantable devices
FR2846550B1 (en) 2002-11-05 2006-01-13 Ldr Medical Prothese of intervertebral disc
GB0301085D0 (en) * 2003-01-17 2003-02-19 Krishna Manoj Articulating spinal disc prosthesis
DE602004018903D1 (en) 2003-02-14 2009-02-26 Depuy Spine Inc intervertebral fusion device prepared in situ
US20050177164A1 (en) * 2003-05-02 2005-08-11 Carmen Walters Pedicle screw devices, systems and methods having a preloaded set screw
US20060229613A1 (en) * 2004-12-31 2006-10-12 Timm Jens P Sheath assembly for spinal stabilization device
US20050182401A1 (en) * 2003-05-02 2005-08-18 Timm Jens P. Systems and methods for spine stabilization including a dynamic junction
US7615068B2 (en) * 2003-05-02 2009-11-10 Applied Spine Technologies, Inc. Mounting mechanisms for pedicle screws and related assemblies
US20050182400A1 (en) 2003-05-02 2005-08-18 Jeffrey White Spine stabilization systems, devices and methods
US6997929B2 (en) * 2003-05-16 2006-02-14 Spine Wave, Inc. Tissue distraction device
DE10323566B4 (en) * 2003-05-26 2006-03-23 Fehling Ag Instrument for unipolar ablation of cardiac tissue
US8926670B2 (en) 2003-06-18 2015-01-06 Roger P. Jackson Polyaxial bone screw assembly
US7967850B2 (en) 2003-06-18 2011-06-28 Jackson Roger P Polyaxial bone anchor with helical capture connection, insert and dual locking assembly
USRE46431E1 (en) 2003-06-18 2017-06-13 Roger P Jackson Polyaxial bone anchor with helical capture connection, insert and dual locking assembly
EP1638485B1 (en) 2003-06-20 2011-03-02 Intrinsic Therapeutics, Inc. Device for delivering an implant through an annular defect in an intervertebral disc
US20050043796A1 (en) * 2003-07-01 2005-02-24 Grant Richard L. Spinal disc nucleus implant
US7753958B2 (en) 2003-08-05 2010-07-13 Gordon Charles R Expandable intervertebral implant
US7799082B2 (en) 2003-08-05 2010-09-21 Flexuspine, Inc. Artificial functional spinal unit system and method for use
US7909869B2 (en) 2003-08-05 2011-03-22 Flexuspine, Inc. Artificial spinal unit assemblies
US8118869B2 (en) * 2006-03-08 2012-02-21 Flexuspine, Inc. Dynamic interbody device
US7708766B2 (en) * 2003-08-11 2010-05-04 Depuy Spine, Inc. Distraction screw
WO2005034781A1 (en) * 2003-09-29 2005-04-21 Promethean Surgical Devices Llc Devices and methods for spine repair
US7255714B2 (en) 2003-09-30 2007-08-14 Michel H. Malek Vertically adjustable intervertebral disc prosthesis
DE10348329B3 (en) * 2003-10-17 2005-02-17 Biedermann Motech Gmbh Rod-shaped element used in spinal column and accident surgery for connecting two bone-anchoring elements comprises a rigid section and an elastic section that are made in one piece
EP1673048B1 (en) * 2003-10-17 2013-06-19 Biedermann Technologies GmbH & Co. KG Flexible implant
US8632570B2 (en) * 2003-11-07 2014-01-21 Biedermann Technologies Gmbh & Co. Kg Stabilization device for bones comprising a spring element and manufacturing method for said spring element
JP2007516738A (en) 2003-10-23 2007-06-28 トランスワン インコーポレイティッド Tools and tool kits for performing minimal intrusion process to the spine
WO2005041793A3 (en) * 2003-10-23 2005-11-10 Steven D Ainsworth Spinal mobility preservation apparatus and method
US7862586B2 (en) * 2003-11-25 2011-01-04 Life Spine, Inc. Spinal stabilization systems
US7553320B2 (en) * 2003-12-10 2009-06-30 Warsaw Orthopedic, Inc. Method and apparatus for replacing the function of facet joints
US7588590B2 (en) 2003-12-10 2009-09-15 Facet Solutions, Inc Spinal facet implant with spherical implant apposition surface and bone bed and methods of use
US8562649B2 (en) 2004-02-17 2013-10-22 Gmedelaware 2 Llc System and method for multiple level facet joint arthroplasty and fusion
US7588578B2 (en) 2004-06-02 2009-09-15 Facet Solutions, Inc Surgical measurement systems and methods
US7763077B2 (en) * 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
US7806914B2 (en) * 2003-12-31 2010-10-05 Spine Wave, Inc. Dynamic spinal stabilization system
US7789912B2 (en) 2004-01-08 2010-09-07 Spine Wave, Inc. Apparatus and method for injecting fluent material at a distracted tissue site
US7556651B2 (en) * 2004-01-09 2009-07-07 Warsaw Orthopedic, Inc. Posterior spinal device and method
US7771479B2 (en) * 2004-01-09 2010-08-10 Warsaw Orthopedic, Inc. Dual articulating spinal device and method
US7875077B2 (en) * 2004-01-09 2011-01-25 Warsaw Orthopedic, Inc. Support structure device and method
US20050171610A1 (en) * 2004-01-09 2005-08-04 Sdgi Holdings, Inc. Mobile bearing spinal device and method
US7901459B2 (en) * 2004-01-09 2011-03-08 Warsaw Orthopedic, Inc. Split spinal device and method
US20050171608A1 (en) * 2004-01-09 2005-08-04 Sdgi Holdings, Inc. Centrally articulating spinal device and method
US20050187631A1 (en) * 2004-01-27 2005-08-25 Sdgi Holdings, Inc. Prosthetic device
US20050165486A1 (en) * 2004-01-27 2005-07-28 Sdgi Holdings, Inc. Prosthetic device and method
US7297146B2 (en) 2004-01-30 2007-11-20 Warsaw Orthopedic, Inc. Orthopedic distraction implants and techniques
FR2865629B1 (en) 2004-02-04 2007-01-26 Ldr Medical Prothese of intervertebral disc
US9050148B2 (en) 2004-02-27 2015-06-09 Roger P. Jackson Spinal fixation tool attachment structure
US7763073B2 (en) 2004-03-09 2010-07-27 Depuy Spine, Inc. Posterior process dynamic spacer
US20050209602A1 (en) * 2004-03-22 2005-09-22 Disc Dynamics, Inc. Multi-stage biomaterial injection system for spinal implants
US20090264939A9 (en) * 2004-12-16 2009-10-22 Martz Erik O Instrument set and method for performing spinal nuclectomy
US20060135959A1 (en) * 2004-03-22 2006-06-22 Disc Dynamics, Inc. Nuclectomy method and apparatus
US7645294B2 (en) 2004-03-31 2010-01-12 Depuy Spine, Inc. Head-to-head connector spinal fixation system
US7717939B2 (en) 2004-03-31 2010-05-18 Depuy Spine, Inc. Rod attachment for head to head cross connector
US7282065B2 (en) 2004-04-09 2007-10-16 X-Spine Systems, Inc. Disk augmentation system and method
US7452351B2 (en) 2004-04-16 2008-11-18 Kyphon Sarl Spinal diagnostic methods and apparatus
US7824390B2 (en) 2004-04-16 2010-11-02 Kyphon SÀRL Spinal diagnostic methods and apparatus
FR2869528B1 (en) 2004-04-28 2007-02-02 Ldr Medical Prothese of intervertebral disc
DE102004021861A1 (en) * 2004-05-04 2005-11-24 Biedermann Motech Gmbh Implant for temporary or permanent replacement of vertebra or intervertebral disk, comprising solid central element and outer elements with openings
US7935136B2 (en) * 2004-06-17 2011-05-03 Alamin Todd F Facet joint fusion devices and methods
US7931675B2 (en) 2004-06-23 2011-04-26 Yale University Dynamic stabilization device including overhanging stabilizing member
US7789913B2 (en) 2004-06-29 2010-09-07 Spine Wave, Inc. Methods for injecting a curable biomaterial into an intervertebral space
WO2006020531A3 (en) * 2004-08-09 2006-04-06 Trans1 Inc Prosthetic nucleus apparatus and methods
US20060036241A1 (en) * 2004-08-11 2006-02-16 Tzony Siegal Spinal surgery system and method
WO2006026425A3 (en) 2004-08-25 2006-04-20 Spine Wave Inc Expandable interbody fusion device
US7717938B2 (en) 2004-08-27 2010-05-18 Depuy Spine, Inc. Dual rod cross connectors and inserter tools
US7887566B2 (en) * 2004-09-16 2011-02-15 Hynes Richard A Intervertebral support device with bias adjustment and related methods
US20060064145A1 (en) * 2004-09-21 2006-03-23 Podhajsky Ronald J Method for treatment of an intervertebral disc
WO2006034436A3 (en) 2004-09-21 2006-10-19 Stout Medical Group Lp Expandable support device and method of use
US20100145424A1 (en) * 2004-09-21 2010-06-10 Covidien Ag Method for Treatment of an Intervertebral Disc
US20080097486A1 (en) * 2004-10-06 2008-04-24 Ross Anthony C Systems and Methods for Direct Restoration of Foraminal Volume
US20080262554A1 (en) * 2004-10-20 2008-10-23 Stanley Kyle Hayes Dyanamic rod
US20090228045A1 (en) * 2004-10-20 2009-09-10 Stanley Kyle Hayes Dynamic rod
US20090030465A1 (en) * 2004-10-20 2009-01-29 Moti Altarac Dynamic rod
US20100036423A1 (en) * 2004-10-20 2010-02-11 Stanley Kyle Hayes Dynamic rod
WO2009042489A3 (en) * 2004-10-20 2009-05-22 Moti Altarac Dynamic rod
US9055981B2 (en) 2004-10-25 2015-06-16 Lanx, Inc. Spinal implants and methods
EP1807012B1 (en) * 2004-10-25 2016-07-06 Lanx, LLC Nterspinous distraction devices
US7833250B2 (en) 2004-11-10 2010-11-16 Jackson Roger P Polyaxial bone screw with helically wound capture connection
US20070162135A1 (en) * 2005-06-15 2007-07-12 Jerome Segal Mechanical apparatus and method for artificial disc replacement
US7648523B2 (en) * 2004-12-08 2010-01-19 Interventional Spine, Inc. Method and apparatus for spinal stabilization
US7857832B2 (en) * 2004-12-08 2010-12-28 Interventional Spine, Inc. Method and apparatus for spinal stabilization
FR2879436B1 (en) 2004-12-22 2007-03-09 Ldr Medical Prothese of intervertebral disc
US20060189985A1 (en) * 2005-02-09 2006-08-24 Lewis David W Device for providing a combination of flexibility and variable force to the spinal column for the treatment of scoliosis
US7294129B2 (en) * 2005-02-18 2007-11-13 Ebi, L.P. Spinal fixation device and associated method
US7993373B2 (en) 2005-02-22 2011-08-09 Hoy Robert W Polyaxial orthopedic fastening apparatus
US8353933B2 (en) 2007-04-17 2013-01-15 Gmedelaware 2 Llc Facet joint replacement
US7722647B1 (en) 2005-03-14 2010-05-25 Facet Solutions, Inc. Apparatus and method for posterior vertebral stabilization
US20060229607A1 (en) * 2005-03-16 2006-10-12 Sdgi Holdings, Inc. Systems, kits and methods for treatment of the spinal column using elongate support members
US7758581B2 (en) * 2005-03-28 2010-07-20 Facet Solutions, Inc. Polyaxial reaming apparatus and method
US8764801B2 (en) 2005-03-28 2014-07-01 Gmedelaware 2 Llc Facet joint implant crosslinking apparatus and method
US20060224219A1 (en) * 2005-03-31 2006-10-05 Sherwood Services Ag Method of using neural stimulation during nucleoplasty procedures
US8470000B2 (en) 2005-04-08 2013-06-25 Paradigm Spine, Llc Interspinous vertebral and lumbosacral stabilization devices and methods of use
US20060241566A1 (en) * 2005-04-11 2006-10-26 Orthox, Llc Nucleus Extraction from Spine Intervertebral Disc
US7674296B2 (en) 2005-04-21 2010-03-09 Globus Medical, Inc. Expandable vertebral prosthesis
WO2006116119A3 (en) * 2005-04-21 2007-11-15 Spine Wave Inc Dynamic stabilization system for the spine
US8702718B2 (en) 2005-04-29 2014-04-22 Jmea Corporation Implantation system for tissue repair
US7632313B2 (en) 2005-04-29 2009-12-15 Jmea Corporation Disc repair system
US7608108B2 (en) * 2005-04-29 2009-10-27 Jmea Corporation Tissue repair system
US20060247776A1 (en) * 2005-05-02 2006-11-02 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for augmenting intervertebral discs
US20060253198A1 (en) * 2005-05-03 2006-11-09 Disc Dynamics, Inc. Multi-lumen mold for intervertebral prosthesis and method of using same
US8795364B2 (en) 2005-05-06 2014-08-05 Kensey Nash Corporation System and devices for the repair of a vertebral disc defect
US20060254599A1 (en) * 2005-05-10 2006-11-16 Levin Bruce H Intervention techniques for post-laminectomy syndrome and other spinal disorders
US20060271048A1 (en) * 2005-05-12 2006-11-30 Jeffery Thramann Pedicle screw based vertebral body stabilization apparatus
US8157815B2 (en) 2005-05-20 2012-04-17 Neotract, Inc. Integrated handle assembly for anchor delivery system
US8491606B2 (en) 2005-05-20 2013-07-23 Neotract, Inc. Median lobe retraction apparatus and method
US8834492B2 (en) 2005-05-20 2014-09-16 Neotract, Inc. Continuous indentation lateral lobe apparatus and method
US8394113B2 (en) 2005-05-20 2013-03-12 Neotract, Inc. Coiled anchor device
US8333776B2 (en) 2005-05-20 2012-12-18 Neotract, Inc. Anchor delivery system
US8668705B2 (en) 2005-05-20 2014-03-11 Neotract, Inc. Latching anchor device
US8628542B2 (en) 2005-05-20 2014-01-14 Neotract, Inc. Median lobe destruction apparatus and method
EP2344048B1 (en) 2008-07-30 2016-09-07 Neotract, Inc. Slotted anchor device
US8425535B2 (en) 2005-05-20 2013-04-23 Neotract, Inc. Multi-actuating trigger anchor delivery system
US9504461B2 (en) 2005-05-20 2016-11-29 Neotract, Inc. Anchor delivery system
US9364212B2 (en) 2005-05-20 2016-06-14 Neotract, Inc. Suture anchoring devices and methods for use
US8603106B2 (en) 2005-05-20 2013-12-10 Neotract, Inc. Integrated handle assembly for anchor delivery system
US7896891B2 (en) 2005-05-20 2011-03-01 Neotract, Inc. Apparatus and method for manipulating or retracting tissue and anatomical structure
US7645286B2 (en) 2005-05-20 2010-01-12 Neotract, Inc. Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues or anatomical structures
US8529584B2 (en) 2005-05-20 2013-09-10 Neotract, Inc. Median lobe band implant apparatus and method
US9149266B2 (en) 2005-05-20 2015-10-06 Neotract, Inc. Deforming anchor device
US7758594B2 (en) 2005-05-20 2010-07-20 Neotract, Inc. Devices, systems and methods for treating benign prostatic hyperplasia and other conditions
US8945152B2 (en) 2005-05-20 2015-02-03 Neotract, Inc. Multi-actuating trigger anchor delivery system
US9549739B2 (en) 2005-05-20 2017-01-24 Neotract, Inc. Devices, systems and methods for treating benign prostatic hyperplasia and other conditions
US7909836B2 (en) 2005-05-20 2011-03-22 Neotract, Inc. Multi-actuating trigger anchor delivery system
US7547319B2 (en) 2005-06-15 2009-06-16 Ouroboros Medical Mechanical apparatus and method for artificial disc replacement
US7442210B2 (en) 2005-06-15 2008-10-28 Jerome Segal Mechanical apparatus and method for artificial disc replacement
US7601172B2 (en) 2005-06-15 2009-10-13 Ouroboros Medical, Inc. Mechanical apparatus and method for artificial disc replacement
US8021426B2 (en) * 2005-06-15 2011-09-20 Ouroboros Medical, Inc. Mechanical apparatus and method for artificial disc replacement
US7828825B2 (en) * 2005-06-20 2010-11-09 Warsaw Orthopedic, Inc. Multi-level multi-functional spinal stabilization systems and methods
FR2887762B1 (en) 2005-06-29 2007-10-12 Ldr Medical Soc Par Actions Si insertion instrumentation intervertebral disk prosthesis between vertebrae
US20070005140A1 (en) * 2005-06-29 2007-01-04 Kim Daniel H Fabrication and use of biocompatible materials for treating and repairing herniated spinal discs
US20070010846A1 (en) * 2005-07-07 2007-01-11 Leung Andrea Y Method of manufacturing an expandable member with substantially uniform profile
WO2007009107A3 (en) 2005-07-14 2008-08-07 Scott E Greenhalgh Expandable support device and method of use
US7824414B2 (en) * 2005-07-22 2010-11-02 Kensey Nash Corporation System and devices for the repair of a vertebral disc defect
US8221462B2 (en) * 2005-08-01 2012-07-17 Globus Medical, Inc. Interspinous internal fixation/distraction device
US7713288B2 (en) * 2005-08-03 2010-05-11 Applied Spine Technologies, Inc. Spring junction and assembly methods for spinal device
US20070055379A1 (en) * 2005-08-03 2007-03-08 Stone Corbett W Annular access devices
US8366773B2 (en) 2005-08-16 2013-02-05 Benvenue Medical, Inc. Apparatus and method for treating bone
US7666226B2 (en) 2005-08-16 2010-02-23 Benvenue Medical, Inc. Spinal tissue distraction devices
US20070073397A1 (en) * 2005-09-15 2007-03-29 Mckinley Laurence M Disc nucleus prosthesis and its method of insertion and revision
FR2891135B1 (en) 2005-09-23 2008-09-12 Ldr Medical Sarl Prothese of intervertebral disc
US7879074B2 (en) * 2005-09-27 2011-02-01 Depuy Spine, Inc. Posterior dynamic stabilization systems and methods
JP5047176B2 (en) * 2005-09-27 2012-10-10 パラダイム・スパイン・リミテッド・ライアビリティ・カンパニーParadigm Spine, LLC. Interspinous stabilization device
US8167915B2 (en) 2005-09-28 2012-05-01 Nuvasive, Inc. Methods and apparatus for treating spinal stenosis
FR2891727B1 (en) * 2005-10-06 2008-09-26 Frederic Fortin Self-blocking device perfected for costal Distractor
WO2007044740A3 (en) * 2005-10-10 2008-04-10 Chad Anthony Barrie Artificial spinal disc replacement system and method
FR2893838B1 (en) 2005-11-30 2008-08-08 Ldr Medical Soc Par Actions Si intervertebral disk prosthesis and instrumentation for inserting the prosthesis between the vertebrae
US8002802B2 (en) * 2005-12-19 2011-08-23 Samy Abdou Devices and methods for inter-vertebral orthopedic device placement
US7988695B2 (en) * 2005-12-21 2011-08-02 Theken Spine, Llc Articulated delivery instrument
US7972337B2 (en) 2005-12-28 2011-07-05 Intrinsic Therapeutics, Inc. Devices and methods for bone anchoring
US9668771B2 (en) 2009-06-15 2017-06-06 Roger P Jackson Soft stabilization assemblies with off-set connector
US7922745B2 (en) * 2006-01-09 2011-04-12 Zimmer Spine, Inc. Posterior dynamic stabilization of the spine
US9168069B2 (en) 2009-06-15 2015-10-27 Roger P. Jackson Polyaxial bone anchor with pop-on shank and winged insert with lower skirt for engaging a friction fit retainer
US8998959B2 (en) 2009-06-15 2015-04-07 Roger P Jackson Polyaxial bone anchors with pop-on shank, fully constrained friction fit retainer and lock and release insert
US7635389B2 (en) 2006-01-30 2009-12-22 Warsaw Orthopedic, Inc. Posterior joint replacement device
US7811326B2 (en) 2006-01-30 2010-10-12 Warsaw Orthopedic Inc. Posterior joint replacement device
US7776075B2 (en) * 2006-01-31 2010-08-17 Warsaw Orthopedic, Inc. Expandable spinal rods and methods of use
FR2897259B1 (en) * 2006-02-15 2008-05-09 Ldr Medical Soc Par Actions Si Transforaminal interbody fusion cage has intervetebrale graft and implanting tool of the cage
WO2007098423A3 (en) 2006-02-17 2007-12-06 Paradigm Spine L L C Method and system for performing interspinous space preparation for receiving an implant
US20070233252A1 (en) * 2006-02-23 2007-10-04 Kim Daniel H Devices, systems and methods for treating intervertebral discs
US7918889B2 (en) * 2006-02-27 2011-04-05 Warsaw Orthopedic, Inc. Expandable spinal prosthetic devices and associated methods
US20070233245A1 (en) * 2006-03-31 2007-10-04 Sdgi Holdings, Inc. Methods and instruments for delivering intervertebral devices
US7699875B2 (en) * 2006-04-17 2010-04-20 Applied Spine Technologies, Inc. Spinal stabilization device with weld cap
US20070255286A1 (en) * 2006-04-27 2007-11-01 Sdgi Holdings, Inc. Devices, apparatus, and methods for improved disc augmentation
US8133279B2 (en) * 2006-04-27 2012-03-13 Warsaw Orthopedic, Inc. Methods for treating an annulus defect of an intervertebral disc
US20070255406A1 (en) * 2006-04-27 2007-11-01 Sdgi Holdings, Inc. Devices, apparatus, and methods for bilateral approach to disc augmentation
DE102007018860A1 (en) * 2006-04-28 2007-10-31 Paradigm Spine, Llc Surgical instrument e.g. forceps, for implanting implantable interspinal device, has guide component connected with elongated sections in hinge area, such that component is held in fixed symmetrical position with respect to surface areas
US20070270821A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Vertebral stabilizer
US8012179B2 (en) * 2006-05-08 2011-09-06 Warsaw Orthopedic, Inc. Dynamic spinal stabilization members and methods
US20070270838A1 (en) * 2006-05-08 2007-11-22 Sdgi Holdings, Inc. Dynamic spinal stabilization device with dampener
US7785350B2 (en) * 2006-05-08 2010-08-31 Warsaw Orthopedic, Inc. Load bearing flexible spinal connecting element
WO2007134113A3 (en) * 2006-05-09 2008-07-24 Raymedica Llc Systems and methods for stabilizing a functional spinal unit
US20070265633A1 (en) * 2006-05-11 2007-11-15 Moon Jon K Implement and method to extract nucleus from spine intervertebral disc
US20070276491A1 (en) * 2006-05-24 2007-11-29 Disc Dynamics, Inc. Mold assembly for intervertebral prosthesis
US8092536B2 (en) * 2006-05-24 2012-01-10 Disc Dynamics, Inc. Retention structure for in situ formation of an intervertebral prosthesis
US9232938B2 (en) 2006-06-13 2016-01-12 Anova Corp. Method and apparatus for closing fissures in the annulus fibrosus
US8834496B2 (en) 2006-06-13 2014-09-16 Bret A. Ferree Soft tissue repair methods and apparatus
US8764835B2 (en) * 2006-06-13 2014-07-01 Bret A. Ferree Intervertebral disc treatment methods and apparatus
US20070299442A1 (en) * 2006-06-26 2007-12-27 Sdgi Holdings, Inc. Vertebral stabilizer
US7927356B2 (en) * 2006-07-07 2011-04-19 Warsaw Orthopedic, Inc. Dynamic constructs for spinal stabilization
WO2008013960A3 (en) * 2006-07-27 2008-12-04 Samy M Abdou Devices and methods for the minimally invasive treatment of spinal stenosis
US20080027444A1 (en) * 2006-07-28 2008-01-31 Malek Michel H Bone anchor device
US8834526B2 (en) 2006-08-09 2014-09-16 Rolando Garcia Methods and apparatus for treating spinal stenosis
US20080039847A1 (en) * 2006-08-09 2008-02-14 Mark Piper Implant and system for stabilization of the spine
US8425601B2 (en) * 2006-09-11 2013-04-23 Warsaw Orthopedic, Inc. Spinal stabilization devices and methods of use
US9017388B2 (en) * 2006-09-14 2015-04-28 Warsaw Orthopedic, Inc. Methods for correcting spinal deformities
US8361117B2 (en) 2006-11-08 2013-01-29 Depuy Spine, Inc. Spinal cross connectors
WO2008067452A1 (en) * 2006-11-30 2008-06-05 Paradigm Spine, Llc Interlaminar-interspinous vertebral stabilization system
EP2124835A4 (en) * 2006-12-22 2013-01-02 Pioneer Surgical Technology Inc Implant retention device and method
JP2010515543A (en) 2007-01-10 2010-05-13 ファセット ソリューションズ インコーポレイテッド Taper lock fixed system
US8241330B2 (en) 2007-01-11 2012-08-14 Lanx, Inc. Spinous process implants and associated methods
US9265532B2 (en) 2007-01-11 2016-02-23 Lanx, Inc. Interspinous implants and methods
US8377098B2 (en) 2007-01-19 2013-02-19 Flexuspine, Inc. Artificial functional spinal unit system and method for use
US8465546B2 (en) 2007-02-16 2013-06-18 Ldr Medical Intervertebral disc prosthesis insertion assemblies
EP2124777A4 (en) 2007-02-21 2013-06-05 Benvenue Medical Inc Devices for treating the spine
EP2124778A4 (en) 2007-02-21 2013-03-20 Benvenue Medical Inc Devices for treating the spine
US7799058B2 (en) * 2007-04-19 2010-09-21 Zimmer Gmbh Interspinous spacer
US8241362B2 (en) 2007-04-26 2012-08-14 Voorhies Rand M Lumbar disc replacement implant for posterior implantation with dynamic spinal stabilization device and method
JP5226066B2 (en) 2007-05-01 2013-07-03 スパイナル シンプリシティ エルエルシーSpinal Simplicity LLC Interspinous implants and methods for embedding it
US8142479B2 (en) * 2007-05-01 2012-03-27 Spinal Simplicity Llc Interspinous process implants having deployable engagement arms
EP2142146A4 (en) * 2007-05-01 2010-12-01 Spinal Simplicity Llc Interspinous implants and methods for implanting same
US20080275504A1 (en) * 2007-05-02 2008-11-06 Bonin Henry K Constructs for dynamic spinal stabilization
US8273124B2 (en) * 2007-05-17 2012-09-25 Depuy Spine, Inc. Self-distracting cage
US7967867B2 (en) 2007-05-31 2011-06-28 Spine Wave, Inc. Expandable interbody fusion device
US7998176B2 (en) 2007-06-08 2011-08-16 Interventional Spine, Inc. Method and apparatus for spinal stabilization
FR2916956B1 (en) 2007-06-08 2012-12-14 Ldr Medical The intersomatic cage, intervertebral prosthesis, the anchoring device and implant instrumentation
US8313515B2 (en) 2007-06-15 2012-11-20 Rachiotek, Llc Multi-level spinal stabilization system
US8864832B2 (en) 2007-06-20 2014-10-21 Hh Spinal Llc Posterior total joint replacement
US8900307B2 (en) 2007-06-26 2014-12-02 DePuy Synthes Products, LLC Highly lordosed fusion cage
US8758366B2 (en) * 2007-07-09 2014-06-24 Neotract, Inc. Multi-actuating trigger anchor delivery system
EP2170227B1 (en) * 2007-07-13 2014-09-03 George Frey Systems for spinal stabilization
US20150119939A1 (en) * 2007-07-13 2015-04-30 George Frey Systems and Methods for Spinal Stabilization
US8672977B2 (en) * 2007-08-09 2014-03-18 Nlt Spine Ltd. Device and method for spinous process distraction
US8080038B2 (en) * 2007-08-17 2011-12-20 Jmea Corporation Dynamic stabilization device for spine
WO2009032695A1 (en) * 2007-08-29 2009-03-12 Trinity Orthopedics, Llc Annulus fibrosus repair device and methods
US20110196492A1 (en) 2007-09-07 2011-08-11 Intrinsic Therapeutics, Inc. Bone anchoring systems
US8323341B2 (en) 2007-09-07 2012-12-04 Intrinsic Therapeutics, Inc. Impaction grafting for vertebral fusion
WO2009046399A1 (en) * 2007-10-05 2009-04-09 Hynes Richard A Spinal stabilization treatment methods for maintaining axial spine height and sagital plane spine balance
US8157844B2 (en) 2007-10-22 2012-04-17 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
US8182514B2 (en) 2007-10-22 2012-05-22 Flexuspine, Inc. Dampener system for a posterior stabilization system with a fixed length elongated member
US8523912B2 (en) 2007-10-22 2013-09-03 Flexuspine, Inc. Posterior stabilization systems with shared, dual dampener systems
US8267965B2 (en) 2007-10-22 2012-09-18 Flexuspine, Inc. Spinal stabilization systems with dynamic interbody devices
US8162994B2 (en) 2007-10-22 2012-04-24 Flexuspine, Inc. Posterior stabilization system with isolated, dual dampener systems
US8187330B2 (en) 2007-10-22 2012-05-29 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
US20090118833A1 (en) * 2007-11-05 2009-05-07 Zimmer Spine, Inc. In-situ curable interspinous process spacer
US20090125032A1 (en) * 2007-11-14 2009-05-14 Gutierrez Robert C Rod removal instrument
WO2009076239A3 (en) * 2007-12-06 2009-08-06 Moti Altarac Spondylolisthesis reduction system and method
US8617214B2 (en) 2008-01-07 2013-12-31 Mmsn Limited Partnership Spinal tension band
US7935133B2 (en) 2008-02-08 2011-05-03 Mmsn Limited Partnership Interlaminar hook
US8252029B2 (en) * 2008-02-21 2012-08-28 Zimmer Gmbh Expandable interspinous process spacer with lateral support and method for implantation
US8267939B2 (en) 2008-02-28 2012-09-18 Stryker Spine Tool for implanting expandable intervertebral implant
US20090222096A1 (en) * 2008-02-28 2009-09-03 Warsaw Orthopedic, Inc. Multi-compartment expandable devices and methods for intervertebral disc expansion and augmentation
US7909857B2 (en) * 2008-03-26 2011-03-22 Warsaw Orthopedic, Inc. Devices and methods for correcting spinal deformities
WO2009124269A1 (en) 2008-04-05 2009-10-08 Synthes Usa, Llc Expandable intervertebral implant
US8430912B2 (en) * 2008-05-05 2013-04-30 Warsaw Orthopedic, Inc. Dynamic stabilization rod
US8211149B2 (en) * 2008-05-12 2012-07-03 Warsaw Orthopedic Elongated members with expansion chambers for treating bony members
US8784453B1 (en) 2008-06-09 2014-07-22 Melvin Law Dynamic spinal stabilization system
US8043340B1 (en) 2008-06-09 2011-10-25 Melvin Law Dynamic spinal stabilization system
EP2339970A2 (en) 2008-07-30 2011-07-06 Neotract, Inc. Anchor delivery system with replaceable cartridge
US8840647B2 (en) 2008-08-05 2014-09-23 The Cleveland Clinic Foundation Facet augmentation
EP2328494B1 (en) * 2008-09-03 2014-10-22 Simpirica Spine, Inc. Apparatus for coupling a prosthesis to a spinal segment
US8187304B2 (en) * 2008-11-10 2012-05-29 Malek Michel H Facet fusion system
JP2012508597A (en) * 2008-11-12 2012-04-12 シンピライカ スパイン, インコーポレイテッド Restraint devices and methods of use are adjusted
WO2010062971A9 (en) 2008-11-26 2010-10-07 Anova Corporation Methods and apparatus for anulus repair
US9492214B2 (en) * 2008-12-18 2016-11-15 Michel H. Malek Flexible spinal stabilization system
US8721723B2 (en) 2009-01-12 2014-05-13 Globus Medical, Inc. Expandable vertebral prosthesis
US9861399B2 (en) 2009-03-13 2018-01-09 Spinal Simplicity, Llc Interspinous process implant having a body with a removable end portion
US8945184B2 (en) * 2009-03-13 2015-02-03 Spinal Simplicity Llc. Interspinous process implant and fusion cage spacer
US8535327B2 (en) 2009-03-17 2013-09-17 Benvenue Medical, Inc. Delivery apparatus for use with implantable medical devices
CN102448392A (en) 2009-03-31 2012-05-09 兰克斯股份有限公司 Spinous process implants and associated methods
WO2010129697A1 (en) 2009-05-06 2010-11-11 Thibodeau Lee L Expandable spinal implant apparatus and method of use
US20110166610A1 (en) * 2009-08-07 2011-07-07 Moti Altarac Systems and methods for stabilization of bone structures, including thorocolumbar stabilization systems and methods
US8747472B2 (en) * 2009-08-14 2014-06-10 Baxano Surgical, Inc. Spinal therapy device with fixated distraction distance
CN102596109B (en) 2009-09-17 2015-10-21 Ldr控股公司 Intervertebral implant having a bone fixation member extendable
US8211126B2 (en) 2009-09-22 2012-07-03 Jmea Corporation Tissue repair system
WO2011057394A1 (en) 2009-11-12 2011-05-19 Anchor Orthopedics Xt, Inc. Devices and methods for treating tissue defects
EP3323390A1 (en) 2009-12-31 2018-05-23 LDR Medical Système intervertébral avec un dispositif d'ancrage
US8591585B2 (en) 2010-04-12 2013-11-26 Globus Medical, Inc. Expandable vertebral implant
US8282683B2 (en) 2010-04-12 2012-10-09 Globus Medical, Inc. Expandable vertebral implant
US8870880B2 (en) 2010-04-12 2014-10-28 Globus Medical, Inc. Angling inserter tool for expandable vertebral implant
US8535380B2 (en) 2010-05-13 2013-09-17 Stout Medical Group, L.P. Fixation device and method
US8979860B2 (en) 2010-06-24 2015-03-17 DePuy Synthes Products. LLC Enhanced cage insertion device
EP2595577A1 (en) 2010-07-21 2013-05-29 NLT Spine Ltd. Spinal surgery implants and delivery system
US9301787B2 (en) 2010-09-27 2016-04-05 Mmsn Limited Partnership Medical apparatus and method for spinal surgery
US9149286B1 (en) 2010-11-12 2015-10-06 Flexmedex, LLC Guidance tool and method for use
US8496689B2 (en) 2011-02-23 2013-07-30 Farzad Massoudi Spinal implant device with fusion cage and fixation plates and method of implanting
US8425560B2 (en) 2011-03-09 2013-04-23 Farzad Massoudi Spinal implant device with fixation plates and lag screws and method of implanting
US9700425B1 (en) 2011-03-20 2017-07-11 Nuvasive, Inc. Vertebral body replacement and insertion methods
US8388687B2 (en) 2011-03-25 2013-03-05 Flexuspine, Inc. Interbody device insertion systems and methods
US9161749B2 (en) 2011-04-14 2015-10-20 Neotract, Inc. Method and apparatus for treating sexual dysfunction
US8814873B2 (en) 2011-06-24 2014-08-26 Benvenue Medical, Inc. Devices and methods for treating bone tissue
JP6047571B2 (en) 2011-08-16 2016-12-21 ストライカー・スピン Expandable graft
EP2747682A4 (en) 2011-08-23 2015-01-21 Flexmedex Llc Tissue removal device and method
US9526627B2 (en) 2011-11-17 2016-12-27 Exactech, Inc. Expandable interbody device system and method
US8911479B2 (en) 2012-01-10 2014-12-16 Roger P. Jackson Multi-start closures for open implants
FR2987256B1 (en) 2012-02-24 2014-08-08 Ldr Medical An anchoring device for intervertebral implant, intervertebral implant and implant instrumentation
CN104582639A (en) 2012-05-29 2015-04-29 Nlt-脊椎有限公司 Laterally deflectable implant
US20140067069A1 (en) 2012-08-30 2014-03-06 Interventional Spine, Inc. Artificial disc
US9433404B2 (en) 2012-10-31 2016-09-06 Suture Concepts Inc. Method and apparatus for closing fissures in the annulus fibrosus
US9949734B2 (en) 2012-10-31 2018-04-24 Suture Concepts Inc. Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations
US8911478B2 (en) 2012-11-21 2014-12-16 Roger P. Jackson Splay control closure for open bone anchor
US8715351B1 (en) 2012-11-29 2014-05-06 Spine Wave, Inc. Expandable interbody fusion device with graft chambers
US9011493B2 (en) * 2012-12-31 2015-04-21 Globus Medical, Inc. Spinous process fixation system and methods thereof
US9757164B2 (en) 2013-01-07 2017-09-12 Spinal Simplicity Llc Interspinous process implant having deployable anchor blades
US8852239B2 (en) 2013-02-15 2014-10-07 Roger P Jackson Sagittal angle screw with integral shank and receiver
US9492288B2 (en) 2013-02-20 2016-11-15 Flexuspine, Inc. Expandable fusion device for positioning between adjacent vertebral bodies
US9522070B2 (en) 2013-03-07 2016-12-20 Interventional Spine, Inc. Intervertebral implant
US8900312B2 (en) 2013-03-12 2014-12-02 Spine Wave, Inc. Expandable interbody fusion device with graft chambers
US8828019B1 (en) 2013-03-13 2014-09-09 Spine Wave, Inc. Inserter for expanding an expandable interbody fusion device
WO2014159225A3 (en) 2013-03-14 2014-11-27 Baxano Surgical, Inc. Spinal implants and implantation system
WO2014150786A1 (en) * 2013-03-15 2014-09-25 Moximed, Inc. Implantation approach and instrumentality for an energy absorbing system
US9522028B2 (en) 2013-07-03 2016-12-20 Interventional Spine, Inc. Method and apparatus for sacroiliac joint fixation
US9566092B2 (en) 2013-10-29 2017-02-14 Roger P. Jackson Cervical bone anchor with collet retainer and outer locking sleeve
US9717533B2 (en) 2013-12-12 2017-08-01 Roger P. Jackson Bone anchor closure pivot-splay control flange form guide and advancement structure
US9451993B2 (en) 2014-01-09 2016-09-27 Roger P. Jackson Bi-radial pop-on cervical bone anchor
US9445921B2 (en) 2014-03-06 2016-09-20 Spine Wave, Inc. Device for expanding and supporting body tissue
US9265623B2 (en) 2014-03-06 2016-02-23 Spine Wave, Inc. Method of expanding a spinal interbody fusion device
US9114026B1 (en) 2014-03-06 2015-08-25 Spine Wave, Inc. Inserter for an expandable spinal interbody fusion device
US9439783B2 (en) 2014-03-06 2016-09-13 Spine Wave, Inc. Inserter for expanding body tissue
US9517144B2 (en) 2014-04-24 2016-12-13 Exactech, Inc. Limited profile intervertebral implant with incorporated fastening mechanism
US9597119B2 (en) 2014-06-04 2017-03-21 Roger P. Jackson Polyaxial bone anchor with polymer sleeve
CN105310758B (en) * 2015-03-18 2017-08-01 周军 A stabilizer and method of using the disc
US9913727B2 (en) 2015-07-02 2018-03-13 Medos International Sarl Expandable implant
US9486323B1 (en) 2015-11-06 2016-11-08 Spinal Stabilization Technologies Llc Nuclear implant apparatus and method following partial nuclectomy

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3426364A (en) * 1966-08-25 1969-02-11 Colorado State Univ Research F Prosthetic appliance for replacing one or more natural vertebrae
US3648691A (en) * 1970-02-24 1972-03-14 Univ Colorado State Res Found Method of applying vertebral appliance
US5423816A (en) * 1993-07-29 1995-06-13 Lin; Chih I. Intervertebral locking device
US5458642A (en) * 1994-01-18 1995-10-17 Beer; John C. Synthetic intervertebral disc
US6610093B1 (en) * 2000-07-28 2003-08-26 Perumala Corporation Method and apparatus for stabilizing adjacent vertebrae
US6626916B1 (en) * 1998-12-31 2003-09-30 Teresa T. Yeung Tissue fastening devices and methods for sustained holding strength

Family Cites Families (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA992255A (en) * 1971-01-25 1976-07-06 Cutter Laboratories Prosthesis for spinal repair
US3875595A (en) * 1974-04-15 1975-04-08 Edward C Froning Intervertebral disc prosthesis and instruments for locating same
US4013078A (en) * 1974-11-25 1977-03-22 Feild James Rodney Intervertebral protector means
US4006747A (en) * 1975-04-23 1977-02-08 Ethicon, Inc. Surgical method
US4141365A (en) * 1977-02-24 1979-02-27 The Johns Hopkins University Epidural lead electrode and insertion needle
US4369788A (en) * 1980-01-31 1983-01-25 Goald Harold J Reversed forceps for microdisc surgery
US4494261A (en) * 1980-12-22 1985-01-22 Spinal Dynamics, Inc. Head and neck cushion
US4501261A (en) * 1982-06-28 1985-02-26 Toto Limited Instantaneous gas water heater
US4490139A (en) * 1983-01-28 1984-12-25 Eli Lilly And Company Implant needle and method
US4580563A (en) * 1983-10-24 1986-04-08 Gross R Michael Arthroscopic surgical instrument and method
US4743260A (en) 1985-06-10 1988-05-10 Burton Charles V Method for a flexible stabilization system for a vertebral column
US4890612A (en) * 1987-02-17 1990-01-02 Kensey Nash Corporation Device for sealing percutaneous puncture in a vessel
US4950234A (en) * 1987-05-26 1990-08-21 Sumitomo Pharmaceuticals Company, Limited Device for administering solid preparations
US4772287A (en) * 1987-08-20 1988-09-20 Cedar Surgical, Inc. Prosthetic disc and method of implanting
US5282856A (en) * 1987-12-22 1994-02-01 Ledergerber Walter J Implantable prosthetic device
US4936827A (en) * 1988-04-11 1990-06-26 Ivy Laboratories, Inc. Implanter applicator
DE8807485U1 (en) * 1988-06-06 1989-08-10 Mecron Medizinische Produkte Gmbh, 1000 Berlin, De
US4911718A (en) * 1988-06-10 1990-03-27 University Of Medicine & Dentistry Of N.J. Functional and biocompatible intervertebral disc spacer
FR2642645B1 (en) 1989-02-03 1992-08-14 Breard Francis flexible intervertebral stabilizer as well as process and apparatus for the control of its tension before installation on the rachis
US5100422A (en) * 1989-05-26 1992-03-31 Impra, Inc. Blood vessel patch
US5201729A (en) 1990-01-12 1993-04-13 Laserscope Method for performing percutaneous diskectomy using a laser
GB9002967D0 (en) * 1990-02-09 1990-04-04 Hundon Forge Ltd Implanting device
US5492697A (en) * 1990-03-05 1996-02-20 Board Of Regents, Univ. Of Texas System Biodegradable implant for fracture nonunions
EP0453393B1 (en) * 1990-04-20 1993-10-06 SULZER Medizinaltechnik AG Implant, particularly intervertebral prosthesis
FR2666981B1 (en) 1990-09-21 1993-06-25 Commarmond Jacques Synthetic vertebral ligament.
DE69123982T2 (en) * 1990-11-20 1997-12-04 Innerdyne Medical Inc Strain sustaining guide member and dilator
US5192326A (en) * 1990-12-21 1993-03-09 Pfizer Hospital Products Group, Inc. Hydrogel bead intervertebral disc nucleus
US5047055A (en) * 1990-12-21 1991-09-10 Pfizer Hospital Products Group, Inc. Hydrogel intervertebral disc nucleus
US5390683A (en) * 1991-02-22 1995-02-21 Pisharodi; Madhavan Spinal implantation methods utilizing a middle expandable implant
EP0525791A1 (en) * 1991-08-02 1993-02-03 DeMatteis, Ralph A. Method and apparatus for laparoscopic repair of hernias
DE4128332A1 (en) 1991-08-27 1993-03-04 Man Ceramics Gmbh Vertebral bone replacement
NL9101489A (en) * 1991-09-03 1993-04-01 Texas Instruments Holland Injector for hypodermically implanting an object into a living being.
US5195541A (en) * 1991-10-18 1993-03-23 Obenchain Theodore G Method of performing laparoscopic lumbar discectomy
US5282827A (en) * 1991-11-08 1994-02-01 Kensey Nash Corporation Hemostatic puncture closure system and method of use
DK168419B1 (en) * 1991-11-25 1994-03-28 Cook Inc A Cook Group Company A support device for abdominal wall and apparatus for the insertion thereof
US5439467A (en) * 1991-12-03 1995-08-08 Vesica Medical, Inc. Suture passer
US5176692A (en) * 1991-12-09 1993-01-05 Wilk Peter J Method and surgical instrument for repairing hernia
US5171279A (en) 1992-03-17 1992-12-15 Danek Medical Method for subcutaneous suprafascial pedicular internal fixation
FR2692952B1 (en) 1992-06-25 1996-04-05 Psi IMPROVED Shock has limit of displacement.
GB9217578D0 (en) * 1992-08-19 1992-09-30 Surgicarft Ltd Surgical implants,etc
US5279555A (en) * 1992-08-24 1994-01-18 Merck & Co., Inc. Device for injecting implants
CA2100532C (en) * 1992-09-21 2004-04-20 David T. Green Device for applying a meniscal staple
US5383905A (en) * 1992-10-09 1995-01-24 United States Surgical Corporation Suture loop locking device
US5383926A (en) * 1992-11-23 1995-01-24 Children's Medical Center Corporation Re-expandable endoprosthesis
US5417699A (en) * 1992-12-10 1995-05-23 Perclose Incorporated Device and method for the percutaneous suturing of a vascular puncture site
US5496318A (en) 1993-01-08 1996-03-05 Advanced Spine Fixation Systems, Inc. Interspinous segmental spine fixation device
US5725577A (en) * 1993-01-13 1998-03-10 Saxon; Allen Prosthesis for the repair of soft tissue defects
EP0683651B1 (en) * 1993-02-10 1999-09-29 Sulzer Spine-Tech Inc. Spinal stabilization surgical tool set
FR2701650B1 (en) 1993-02-17 1995-05-24 Psi Double damper for intervertebral stabilization.
US5439464A (en) * 1993-03-09 1995-08-08 Shapiro Partners Limited Method and instruments for performing arthroscopic spinal surgery
US5415661A (en) 1993-03-24 1995-05-16 University Of Miami Implantable spinal assist device
US5398861A (en) * 1993-04-16 1995-03-21 United States Surgical Corporation Device for driving surgical fasteners
US5534028A (en) * 1993-04-20 1996-07-09 Howmedica, Inc. Hydrogel intervertebral disc nucleus with diminished lateral bulging
EP0621020A1 (en) 1993-04-21 1994-10-26 SULZER Medizinaltechnik AG Intervertebral prosthesis and method of implanting such a prosthesis
US5500000A (en) * 1993-07-01 1996-03-19 United States Surgical Corporation Soft tissue repair system and method
FR2709247B1 (en) * 1993-08-27 1995-09-29 Martin Jean Raymond Device for anchoring a spinal instrumentation of a vertebra.
FR2709246B1 (en) 1993-08-27 1995-09-29 Martin Jean Raymond dynamic spinal orthosis implanted.
US5397332A (en) * 1993-09-02 1995-03-14 Ethicon, Inc. Surgical mesh applicator
US5433739A (en) 1993-11-02 1995-07-18 Sluijter; Menno E. Method and apparatus for heating an intervertebral disc for relief of back pain
FR2712481B1 (en) 1993-11-18 1996-01-12 Graf Henry Improvements to flexible inter-vertebral stabilizers.
CA2144211C (en) * 1994-03-16 2005-05-24 David T. Green Surgical instruments useful for endoscopic spinal procedures
US5571189A (en) * 1994-05-20 1996-11-05 Kuslich; Stephen D. Expandable fabric implant for stabilizing the spinal motion segment
US6187048B1 (en) * 1994-05-24 2001-02-13 Surgical Dynamics, Inc. Intervertebral disc implant
US5725552A (en) * 1994-07-08 1998-03-10 Aga Medical Corporation Percutaneous catheter directed intravascular occlusion devices
FR2722980B1 (en) 1994-07-26 1996-09-27 Samani Jacques inter-vertebral implant thorny
DE69522060D1 (en) * 1994-09-08 2001-09-13 Stryker Technologies Corp Spinal disc nucleus of hydrogel
US5730744A (en) * 1994-09-27 1998-03-24 Justin; Daniel F. Soft tissue screw, delivery device, and method
US6171318B1 (en) * 1994-09-29 2001-01-09 Bard Asdi Inc. Hernia mesh patch with stiffening layer
US5785705A (en) 1994-10-11 1998-07-28 Oratec Interventions, Inc. RF method for controlled depth ablation of soft tissue
US6022376A (en) * 1997-06-06 2000-02-08 Raymedica, Inc. Percutaneous prosthetic spinal disc nucleus and method of manufacture
US5824093A (en) * 1994-10-17 1998-10-20 Raymedica, Inc. Prosthetic spinal disc nucleus
US5674296A (en) * 1994-11-14 1997-10-07 Spinal Dynamics Corporation Human spinal disc prosthesis
US6171329B1 (en) * 1994-12-19 2001-01-09 Gore Enterprise Holdings, Inc. Self-expanding defect closure device and method of making and using
US5716413A (en) * 1995-10-11 1998-02-10 Osteobiologics, Inc. Moldable, hand-shapable biodegradable implant material
ES2211895T5 (en) 1995-11-08 2009-10-29 Zimmer Gmbh intervertebral prothesis.
US5645597A (en) * 1995-12-29 1997-07-08 Krapiva; Pavel I. Disc replacement method and apparatus
US5865845A (en) * 1996-03-05 1999-02-02 Thalgott; John S. Prosthetic intervertebral disc
US5823994A (en) 1996-03-15 1998-10-20 Oratec Interventions, Inc. Method and apparatus for soft tissue fixation
ES2213174T3 (en) 1996-03-27 2004-08-16 Josef Cech Device for correcting spinal deformities.
US5716408A (en) * 1996-05-31 1998-02-10 C.R. Bard, Inc. Prosthesis for hernia repair and soft tissue reconstruction
US5728150A (en) * 1996-07-29 1998-03-17 Cardiovascular Dynamics, Inc. Expandable microporous prosthesis
US6007570A (en) 1996-08-13 1999-12-28 Oratec Interventions, Inc. Apparatus with functional element for performing function upon intervertebral discs
US6126682A (en) 1996-08-13 2000-10-03 Oratec Interventions, Inc. Method for treating annular fissures in intervertebral discs
US5980504A (en) 1996-08-13 1999-11-09 Oratec Interventions, Inc. Method for manipulating tissue of an intervertebral disc
US6258086B1 (en) * 1996-10-23 2001-07-10 Oratec Interventions, Inc. Catheter for delivery of energy to a surgical site
US6068628A (en) 1996-08-20 2000-05-30 Oratec Interventions, Inc. Apparatus for treating chondromalacia
US5716416A (en) 1996-09-10 1998-02-10 Lin; Chih-I Artificial intervertebral disk and method for implanting the same
US5716409A (en) * 1996-10-16 1998-02-10 Debbas; Elie Reinforcement sheet for use in surgical repair
US6019793A (en) * 1996-10-21 2000-02-01 Synthes Surgical prosthetic device
FR2755844B1 (en) * 1996-11-15 1999-01-29 Stryker France Sa Osteosynthesis system of elastic deformation has to spine
US5860977A (en) 1997-01-02 1999-01-19 Saint Francis Medical Technologies, Llc Spine distraction implant and method
US6168593B1 (en) 1997-02-12 2001-01-02 Oratec Interventions, Inc. Electrode for electrosurgical coagulation of tissue
US6135999A (en) 1997-02-12 2000-10-24 Oratec Internationals, Inc. Concave probe for arthroscopic surgery
US5954716A (en) 1997-02-19 1999-09-21 Oratec Interventions, Inc Method for modifying the length of a ligament
US5984925A (en) 1997-07-30 1999-11-16 Cross Medical Products, Inc. Longitudinally adjustable bone plates and method for use thereof
US6511958B1 (en) * 1997-08-14 2003-01-28 Sulzer Biologics, Inc. Compositions for regeneration and repair of cartilage lesions
US6004320A (en) 1997-09-19 1999-12-21 Oratec Interventions, Inc. Clip on electrocauterizing sheath for orthopedic shave devices
US6007533A (en) 1997-09-19 1999-12-28 Oratec Interventions, Inc. Electrocauterizing tip for orthopedic shave devices
US6309420B1 (en) * 1997-10-14 2001-10-30 Parallax Medical, Inc. Enhanced visibility materials for implantation in hard tissue
US6146380A (en) * 1998-01-09 2000-11-14 Radionics, Inc. Bent tip electrical surgical probe
EP1054634A4 (en) * 1998-02-10 2006-03-29 Artemis Medical Inc Entrapping apparatus and method for use
US5989291A (en) 1998-02-26 1999-11-23 Third Millennium Engineering, Llc Intervertebral spacer device
US6019792A (en) * 1998-04-23 2000-02-01 Cauthen Research Group, Inc. Articulating spinal implant
JP2002512079A (en) * 1998-04-23 2002-04-23 コーゼン リサーチ グループ インク. Articulated spine implant
US6224630B1 (en) 1998-05-29 2001-05-01 Advanced Bio Surfaces, Inc. Implantable tissue repair device
DE69942858D1 (en) * 1998-06-01 2010-11-25 Kyphon S A R L Expandable, preformed structures for folding in regions within the body
US6132465A (en) * 1998-06-04 2000-10-17 Raymedica, Inc. Tapered prosthetic spinal disc nucleus
US6045561A (en) * 1998-06-23 2000-04-04 Orthopaedic Biosystems Ltd., Inc. Surgical knot manipulator
US6146422A (en) * 1999-01-25 2000-11-14 Lawson; Kevin Jon Prosthetic nucleus replacement for surgical reconstruction of intervertebral discs and treatment method
US6183518B1 (en) * 1999-02-22 2001-02-06 Anthony C. Ross Method of replacing nucleus pulposus and repairing the intervertebral disk
US6110210A (en) * 1999-04-08 2000-08-29 Raymedica, Inc. Prosthetic spinal disc nucleus having selectively coupled bodies
US6428576B1 (en) * 1999-04-16 2002-08-06 Endospine, Ltd. System for repairing inter-vertebral discs
US6387130B1 (en) * 1999-04-16 2002-05-14 Nuvasive, Inc. Segmented linked intervertebral implant systems
US6162217A (en) 1999-04-21 2000-12-19 Oratec Interventions, Inc. Method and apparatus for controlling a temperature-controlled probe
US6296643B1 (en) * 1999-04-23 2001-10-02 Sdgi Holdings, Inc. Device for the correction of spinal deformities through vertebral body tethering without fusion
US6245107B1 (en) * 1999-05-28 2001-06-12 Bret A. Ferree Methods and apparatus for treating disc herniation
US6371990B1 (en) * 1999-10-08 2002-04-16 Bret A. Ferree Annulus fibrosis augmentation methods and apparatus
US20030004574A1 (en) * 1999-10-08 2003-01-02 Ferree Bret A. Disc and annulus augmentation using biologic tissue
US6344058B1 (en) * 1999-08-13 2002-02-05 Bret A. Ferree Treating degenerative disc disease through transplantation of allograft disc and vertebral endplates
US6685695B2 (en) * 1999-08-13 2004-02-03 Bret A. Ferree Method and apparatus for providing nutrition to intervertebral disc tissue
US20030026788A1 (en) * 1999-10-08 2003-02-06 Ferree Bret A. Use of extracellular matrix tissue to preserve cultured cell phenotype
US6340369B1 (en) * 1999-08-13 2002-01-22 Bret A. Ferree Treating degenerative disc disease with harvested disc cells and analogues of the extracellular matrix
WO2002054978A3 (en) * 1999-08-18 2002-11-07 Intrinsic Therapeutics, Inc. Devices and method for nucleus pulposus augmentation and retention
US7717961B2 (en) * 1999-08-18 2010-05-18 Intrinsic Therapeutics, Inc. Apparatus delivery in an intervertebral disc
US6508839B1 (en) * 1999-08-18 2003-01-21 Intrinsic Orthopedics, Inc. Devices and methods of vertebral disc augmentation
US20040024465A1 (en) * 1999-08-18 2004-02-05 Gregory Lambrecht Devices and method for augmenting a vertebral disc
US6425919B1 (en) 1999-08-18 2002-07-30 Intrinsic Orthopedics, Inc. Devices and methods of vertebral disc augmentation
US7220281B2 (en) * 1999-08-18 2007-05-22 Intrinsic Therapeutics, Inc. Implant for reinforcing and annulus fibrosis
US6429013B1 (en) * 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
US6171317B1 (en) * 1999-09-14 2001-01-09 Perclose, Inc. Knot tying device and method
US6264695B1 (en) * 1999-09-30 2001-07-24 Replication Medical, Inc. Spinal nucleus implant
US20030040796A1 (en) * 1999-10-08 2003-02-27 Ferree Bret A. Devices used to treat disc herniation and attachment mechanisms therefore
WO2001028464A1 (en) 1999-10-20 2001-04-26 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US7153312B1 (en) * 1999-12-02 2006-12-26 Smith & Nephew Inc. Closure device and method for tissue repair
US6684886B1 (en) * 2000-01-21 2004-02-03 Prospine, Inc. Intervertebral disc repair methods and apparatus
US6558390B2 (en) * 2000-02-16 2003-05-06 Axiamed, Inc. Methods and apparatus for performing therapeutic procedures in the spine
US6558386B1 (en) * 2000-02-16 2003-05-06 Trans1 Inc. Axial spinal implant and method and apparatus for implanting an axial spinal implant within the vertebrae of the spine
US7014633B2 (en) * 2000-02-16 2006-03-21 Trans1, Inc. Methods of performing procedures in the spine
US6514255B1 (en) * 2000-02-25 2003-02-04 Bret Ferree Sublaminar spinal fixation apparatus
US6336930B1 (en) * 2000-03-07 2002-01-08 Zimmer, Inc. Polymer filled bone plate
US6689125B1 (en) * 2000-04-04 2004-02-10 Spinalabs, Llc Devices and methods for the treatment of spinal disorders
US20020026244A1 (en) * 2000-08-30 2002-02-28 Trieu Hai H. Intervertebral disc nucleus implants and methods
US6620196B1 (en) * 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
DE60035378T2 (en) * 2000-09-07 2008-02-28 Covidien Ag Device for the treatment of intervertebral discs
US6648893B2 (en) * 2000-10-27 2003-11-18 Blackstone Medical, Inc. Facet fixation devices
EP1328222B1 (en) * 2000-10-27 2005-03-30 SDGI Holdings, Inc. Annulus repair system
US6508828B1 (en) * 2000-11-03 2003-01-21 Radi Medical Systems Ab Sealing device and wound closure device
US20040024463A1 (en) * 2001-08-27 2004-02-05 Thomas James C. Expandable implant for partial disc replacement and reinforcement of a disc partially removed in a discectomy and for reduction and maintenance of alignment of cancellous bone fractures and methods and apparatuses for same
WO2003049669A3 (en) * 2001-12-10 2004-03-11 Colbar R & D Ltd Methods, devices, and preparations for intervertebral disc treatment
US20040010315A1 (en) * 2002-03-29 2004-01-15 Song John K. Self-expanding intervertebral device
US6878167B2 (en) * 2002-04-24 2005-04-12 Bret A. Ferree Methods and apparatus for placing intradiscal devices
WO2003095026A1 (en) * 2002-05-13 2003-11-20 Pflueger D Russell Spinal disc therapy system
US6945933B2 (en) * 2002-06-26 2005-09-20 Sdgi Holdings, Inc. Instruments and methods for minimally invasive tissue retraction and surgery
US20040002763A1 (en) * 2002-06-27 2004-01-01 Raymedica, Inc. Spinal disc anulus occlusion device and method of use
US7033393B2 (en) * 2002-06-27 2006-04-25 Raymedica, Inc. Self-transitioning spinal disc anulus occulsion device and method of use
US6723097B2 (en) * 2002-07-23 2004-04-20 Depuy Spine, Inc. Surgical trial implant
US6958078B2 (en) * 2002-08-19 2005-10-25 The University Of Toledo Bioartificial intervertebral disc

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3426364A (en) * 1966-08-25 1969-02-11 Colorado State Univ Research F Prosthetic appliance for replacing one or more natural vertebrae
US3648691A (en) * 1970-02-24 1972-03-14 Univ Colorado State Res Found Method of applying vertebral appliance
US5423816A (en) * 1993-07-29 1995-06-13 Lin; Chih I. Intervertebral locking device
US5458642A (en) * 1994-01-18 1995-10-17 Beer; John C. Synthetic intervertebral disc
US6626916B1 (en) * 1998-12-31 2003-09-30 Teresa T. Yeung Tissue fastening devices and methods for sustained holding strength
US6610093B1 (en) * 2000-07-28 2003-08-26 Perumala Corporation Method and apparatus for stabilizing adjacent vertebrae

Cited By (678)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070055246A1 (en) * 1997-01-02 2007-03-08 St. Francis Medical Technologies, Inc. Spine distraction implant and method
US7901432B2 (en) 1997-01-02 2011-03-08 Kyphon Sarl Method for lateral implantation of spinous process spacer
US7955356B2 (en) 1997-01-02 2011-06-07 Kyphon Sarl Laterally insertable interspinous process implant
US7993374B2 (en) 1997-01-02 2011-08-09 Kyphon Sarl Supplemental spine fixation device and method
US20040167520A1 (en) * 1997-01-02 2004-08-26 St. Francis Medical Technologies, Inc. Spinous process implant with tethers
US20040220568A1 (en) * 1997-01-02 2004-11-04 St. Francis Medical Technologies, Inc. Method for lateral implantation of spinous process spacer
US7828822B2 (en) 1997-01-02 2010-11-09 Kyphon SÀRL Spinous process implant
US20100262243A1 (en) * 1997-01-02 2010-10-14 Kyphon Sarl Spine distraction implant
US8029542B2 (en) 1997-01-02 2011-10-04 Kyphon Sarl Supplemental spine fixation device and method
US7918877B2 (en) 1997-01-02 2011-04-05 Kyphon Sarl Lateral insertion method for spinous process spacer with deployable member
US7758619B2 (en) 1997-01-02 2010-07-20 Kyphon SÀRL Spinous process implant with tethers
US7749253B2 (en) 1997-01-02 2010-07-06 Kyphon SÀRL Spine distraction implant and method
US20100082108A1 (en) * 1997-01-02 2010-04-01 Kyphon Sarl Spine distraction implant and method
US7666209B2 (en) 1997-01-02 2010-02-23 Kyphon Sarl Spine distraction implant and method
US20050228384A1 (en) * 1997-01-02 2005-10-13 St. Francis Medical Technologies, Inc. Spinous process implant with tethers
US20050228383A1 (en) * 1997-01-02 2005-10-13 St. Francis Medical Technologies, Inc. Lateral insertion method for spinous process spacer with deployable member
US8128661B2 (en) 1997-01-02 2012-03-06 Kyphon Sarl Interspinous process distraction system and method with positionable wing and method
US20100004744A1 (en) * 1997-01-02 2010-01-07 Kyphon Sarl Interspinous process distraction system and method with positionable wing and method
US8157840B2 (en) 1997-01-02 2012-04-17 Kyphon Sarl Spine distraction implant and method
US7635377B2 (en) 1997-01-02 2009-12-22 Kyphon Sarl Spine distraction implant and method
US8216277B2 (en) 1997-01-02 2012-07-10 Kyphon Sarl Spine distraction implant and method
US8349013B2 (en) 1997-01-02 2013-01-08 Kyphon Sarl Spine distraction implant
US8540751B2 (en) 1997-01-02 2013-09-24 Warsaw Orthopedic, Inc. Spine distraction implant and method
US8568454B2 (en) 1997-01-02 2013-10-29 Warsaw Orthopedic, Inc. Spine distraction implant and method
US8568460B2 (en) 1997-01-02 2013-10-29 Warsaw Orthopedic, Inc. Spine distraction implant and method
US20080183210A1 (en) * 1997-01-02 2008-07-31 Zucherman James F Supplemental spine fixation device and method
US8568455B2 (en) 1997-01-02 2013-10-29 Warsaw Orthopedic, Inc. Spine distraction implant and method
US20080172057A1 (en) * 1997-01-02 2008-07-17 Zucherman James F Spine distraction implant and method
US8617211B2 (en) 1997-01-02 2013-12-31 Warsaw Orthopedic, Inc. Spine distraction implant and method
US8672975B2 (en) 1997-01-02 2014-03-18 Warsaw Orthopedic, Inc Spine distraction implant and method
US8672974B2 (en) 1997-01-02 2014-03-18 Warsaw Orthopedic, Inc. Spine distraction implant and method
US20080071378A1 (en) * 1997-01-02 2008-03-20 Zucherman James F Spine distraction implant and method
US20080288075A1 (en) * 1997-01-02 2008-11-20 Zucherman James F Spine distraction implant and method
US20080065086A1 (en) * 1997-01-02 2008-03-13 Zucherman James F Spine distraction implant and method
US8740943B2 (en) 1997-01-02 2014-06-03 Warsaw Orthopedic, Inc. Spine distraction implant and method
US20080058941A1 (en) * 1997-01-02 2008-03-06 Zucherman James F Supplemental spine fixation device and method
US20080051785A1 (en) * 1997-01-02 2008-02-28 Zucherman James F Spine distraction implant and method
US20080051905A1 (en) * 1997-01-02 2008-02-28 Zucherman James F Supplemental spine fixation device and method
US20080046088A1 (en) * 1997-01-02 2008-02-21 Zucherman James F Spine distraction implant and method
US8821548B2 (en) 1997-01-02 2014-09-02 Warsaw Orthopedic, Inc. Spine distraction implant and method
US20080045959A1 (en) * 1997-01-02 2008-02-21 Zucherman James F Spine distraction implant and method
US20080046089A1 (en) * 1997-01-02 2008-02-21 Zucherman James F Spine distraction implant and method
US20080039859A1 (en) * 1997-01-02 2008-02-14 Zucherman James F Spine distraction implant and method
US20080039853A1 (en) * 1997-01-02 2008-02-14 Zucherman James F Spine distraction implant and method
US20060235521A1 (en) * 1997-01-02 2006-10-19 St. Francis Medical Technologies, Inc. Spinous process implant with tethers
US20080039858A1 (en) * 1997-01-02 2008-02-14 Zucherman James F Spine distraction implant and method
US20080033445A1 (en) * 1997-01-02 2008-02-07 Zucherman James F Spine distraction implant and method
US20080027553A1 (en) * 1997-01-02 2008-01-31 Zucherman James F Spine distraction implant and method
US20080027552A1 (en) * 1997-01-02 2008-01-31 Zucherman James F Spine distraction implant and method
US8828017B2 (en) 1997-01-02 2014-09-09 Warsaw Orthopedic, Inc. Spine distraction implant and method
US20080021560A1 (en) * 1997-01-02 2008-01-24 Zucherman James F Spine distraction implant and method
US20080015700A1 (en) * 1997-01-02 2008-01-17 Zucherman James F Spine distraction implant and method
US20070265624A1 (en) * 1997-01-02 2007-11-15 Zucherman Jamesq F Spine distraction implant and method
US20070208347A1 (en) * 1997-01-02 2007-09-06 Zucherman James F Spine distraction implant and method
US20070203493A1 (en) * 1997-01-02 2007-08-30 Zucherman James F Spine distraction implant and method
US20070203490A1 (en) * 1997-01-02 2007-08-30 Zucherman James F Spine distraction implant and method
US20070203495A1 (en) * 1997-01-02 2007-08-30 Zucherman James F Spine distraction implant and method
US20070203497A1 (en) * 1997-01-02 2007-08-30 Zucherman James F Spine distraction implant and method
US20070203501A1 (en) * 1997-01-02 2007-08-30 Zucherman James F Spine distraction implant and method
US8128663B2 (en) 1997-01-02 2012-03-06 Kyphon Sarl Spine distraction implant
US20040153071A1 (en) * 1998-10-27 2004-08-05 St. Francis Medical Technologies, Inc. Interspinous process distraction system and method with positionable wing and method
US8556977B2 (en) 1999-10-20 2013-10-15 Anulex Technologies, Inc. Tissue anchoring system and method
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US9095442B2 (en) 1999-10-20 2015-08-04 Krt Investors, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US9675347B2 (en) 1999-10-20 2017-06-13 Krt Investors, Inc. Apparatus for the treatment of tissue
US9114025B2 (en) 1999-10-20 2015-08-25 Krt Investors, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US8172880B2 (en) 1999-12-01 2012-05-08 Warsaw Orthopedic, Inc. Intervertebral stabilising device
US20080065078A1 (en) * 1999-12-01 2008-03-13 Henry Graf Intervertebral stabilising device
US20100145336A1 (en) * 2001-03-28 2010-06-10 Moximed, Inc. Bone fixated, articulated joint load control device
US20090248026A1 (en) * 2001-03-28 2009-10-01 Moximed, Inc. Bone fixated, articulated joint load control device
US9943336B2 (en) * 2001-03-28 2018-04-17 Moximed, Inc. Bone fixated, articulated joint load control device
US20050261680A1 (en) * 2001-03-28 2005-11-24 Imperial College Innovations Ltd. Bone fixated, articulated joint load control device
US7763020B2 (en) 2001-03-28 2010-07-27 Moximed, Inc. Bone fixated, articulated joint load control device
US9610103B2 (en) 2001-03-28 2017-04-04 Moximed, Inc. Bone fixated, articulated joint load control device
US20090030523A1 (en) * 2001-08-08 2009-01-29 Jean Taylor Veretebra Stabilizing Assembly
US8012180B2 (en) 2001-12-07 2011-09-06 Synthes Usa, Llc Damping element and device for stabilization of adjacent vertebral bodies
US20080033435A1 (en) * 2001-12-07 2008-02-07 Armin Studer Damping element and device for stabilization of adjacent vertebral bodies
US20040143264A1 (en) * 2002-08-23 2004-07-22 Mcafee Paul C. Metal-backed UHMWPE rod sleeve system preserving spinal motion
US8814913B2 (en) 2002-09-06 2014-08-26 Roger P Jackson Helical guide and advancement flange with break-off extensions
US20060136060A1 (en) * 2002-09-10 2006-06-22 Jean Taylor Posterior vertebral support assembly
US7776069B2 (en) 2002-09-10 2010-08-17 Kyphon SÀRL Posterior vertebral support assembly
US8043336B2 (en) 2002-09-10 2011-10-25 Warsaw Orthopedic, Inc. Posterior vertebral support assembly
US20100121456A1 (en) * 2002-09-10 2010-05-13 Kyphon Sarl Posterior vertebral support assembly
US7335200B2 (en) * 2002-10-14 2008-02-26 Scient'x Dynamic intervertebral connection device with controlled multidirectional deflection
US20040073215A1 (en) * 2002-10-14 2004-04-15 Scient ' X Dynamic intervertebral connection device with controlled multidirectional deflection
US8221463B2 (en) 2002-10-29 2012-07-17 Kyphon Sarl Interspinous process implants and methods of use
US7803190B2 (en) 2002-10-29 2010-09-28 Kyphon SÀRL Interspinous process apparatus and method with a selectably expandable spacer
US20080051899A1 (en) * 2002-10-29 2008-02-28 Zucherman James F Interspinous process implants and methods of use
US8007537B2 (en) 2002-10-29 2011-08-30 Kyphon Sarl Interspinous process implants and methods of use
US20080033558A1 (en) * 2002-10-29 2008-02-07 Zucherman James F Interspinous process implants and methods of use
US20080033559A1 (en) * 2002-10-29 2008-02-07 Zucherman James F Interspinous process implants and methods of use
US20050075634A1 (en) * 2002-10-29 2005-04-07 Zucherman James F. Interspinous process implant with radiolucent spacer and lead-in tissue expander
US7833246B2 (en) 2002-10-29 2010-11-16 Kyphon SÀRL Interspinous process and sacrum implant and method
US20080039947A1 (en) * 2002-10-29 2008-02-14 Zucherman James F Interspinous process implants and methods of use
US20080065212A1 (en) * 2002-10-29 2008-03-13 Zucherman James F Interspinous process implants and methods of use
US20100305611A1 (en) * 2002-10-29 2010-12-02 Kyphon Sarl Interspinous process apparatus and method with a selectably expandable spacer
US20080065213A1 (en) * 2002-10-29 2008-03-13 Zucherman James F Interspinous process implants and methods of use
US8454659B2 (en) 2002-10-29 2013-06-04 Kyphon Sarl Interspinous process implants and methods of use
US20040097931A1 (en) * 2002-10-29 2004-05-20 Steve Mitchell Interspinous process and sacrum implant and method
US8092535B2 (en) 2002-10-29 2012-01-10 Kyphon Sarl Interspinous process implants and methods of use
US20080027545A1 (en) * 2002-10-29 2008-01-31 Zucherman James F Interspinous process implants and methods of use
US20080033560A1 (en) * 2002-10-29 2008-02-07 Zucherman James F Interspinous process implants and methods of use
US7662187B2 (en) 2002-10-29 2010-02-16 Kyphon Sarl Interspinous process implants and methods of use
US8894686B2 (en) 2002-10-29 2014-11-25 Warsaw Orthopedic, Inc. Interspinous process implants and methods of use
US20080021468A1 (en) * 2002-10-29 2008-01-24 Zucherman James F Interspinous process implants and methods of use
US20080021471A1 (en) * 2003-02-12 2008-01-24 Kyphon Inc. System and Method for Immobilizing Adjacent Spinous Processes
US7588592B2 (en) 2003-02-12 2009-09-15 Kyphon Sarl System and method for immobilizing adjacent spinous processes
US8092502B2 (en) 2003-04-09 2012-01-10 Jackson Roger P Polyaxial bone screw with uploaded threaded shank and method of assembly and use
US8540753B2 (en) 2003-04-09 2013-09-24 Roger P. Jackson Polyaxial bone screw with uploaded threaded shank and method of assembly and use
US9655651B2 (en) 2003-05-02 2017-05-23 Yale University Dynamic spine stabilizer
US20050177156A1 (en) * 2003-05-02 2005-08-11 Timm Jens P. Surgical implant devices and systems including a sheath member
US9034016B2 (en) 2003-05-02 2015-05-19 Yale University Dynamic spine stabilizer
US20050171543A1 (en) * 2003-05-02 2005-08-04 Timm Jens P. Spine stabilization systems and associated devices, assemblies and methods
US20100174317A1 (en) * 2003-05-02 2010-07-08 Applied Spine Technologies, Inc. Dynamic Spine Stabilizer
US20050222569A1 (en) * 2003-05-02 2005-10-06 Panjabi Manohar M Dynamic spine stabilizer
US20050245930A1 (en) * 2003-05-02 2005-11-03 Timm Jens P Dynamic spine stabilizer
US8333790B2 (en) 2003-05-02 2012-12-18 Yale University Dynamic spine stabilizer
US7988707B2 (en) 2003-05-02 2011-08-02 Yale University Dynamic spine stabilizer
US8652175B2 (en) 2003-05-02 2014-02-18 Rachiotek, Llc Surgical implant devices and systems including a sheath member
US7713287B2 (en) 2003-05-02 2010-05-11 Applied Spine Technologies, Inc. Dynamic spine stabilizer
US7476238B2 (en) 2003-05-02 2009-01-13 Yale University Dynamic spine stabilizer
US7695513B2 (en) 2003-05-22 2010-04-13 Kyphon Sarl Distractible interspinous process implant and method of implantation
US8888816B2 (en) 2003-05-22 2014-11-18 Warsaw Orthopedic, Inc. Distractible interspinous process implant and method of implantation
US20060264939A1 (en) * 2003-05-22 2006-11-23 St. Francis Medical Technologies, Inc. Interspinous process implant with slide-in distraction piece and method of implantation
US8070778B2 (en) 2003-05-22 2011-12-06 Kyphon Sarl Interspinous process implant with slide-in distraction piece and method of implantation
US20100174316A1 (en) * 2003-05-22 2010-07-08 Kyphon Sarl Distractible interspinous process implant and method of implantation
US8048117B2 (en) 2003-05-22 2011-11-01 Kyphon Sarl Interspinous process implant and method of implantation
US20050203514A1 (en) * 2003-09-24 2005-09-15 Tae-Ahn Jahng Adjustable spinal stabilization system
US20080234746A1 (en) * 2003-09-24 2008-09-25 N Spine, Inc. Spinal stabilization device
US7988710B2 (en) 2003-09-24 2011-08-02 N Spine, Inc. Spinal stabilization device
US20070123871A1 (en) * 2003-09-24 2007-05-31 Tae-Ahn Jahng Method and apparatus for flexible fixation of a spine
US20060195093A1 (en) * 2003-09-24 2006-08-31 Tae-Ahn Jahng Method and apparatus for flexible fixation of a spine
US8623057B2 (en) 2003-09-24 2014-01-07 DePuy Synthes Products, LLC Spinal stabilization device
US20070276380A1 (en) * 2003-09-24 2007-11-29 Tae-Ahn Jahng Spinal stabilization device
US8968366B2 (en) 2003-09-24 2015-03-03 DePuy Synthes Products, LLC Method and apparatus for flexible fixation of a spine
US20050177157A1 (en) * 2003-09-24 2005-08-11 N Spine, Inc. Method and apparatus for flexible fixation of a spine
US8979900B2 (en) * 2003-09-24 2015-03-17 DePuy Synthes Products, LLC Spinal stabilization device
US20110106167A1 (en) * 2003-09-24 2011-05-05 Tae-Ahn Jahng Adjustable spinal stabilization system
US20070225710A1 (en) * 2003-09-24 2007-09-27 Tae-Ahn Jahng Spinal stabilization device
US7815665B2 (en) 2003-09-24 2010-10-19 N Spine, Inc. Adjustable spinal stabilization system
US7993370B2 (en) 2003-09-24 2011-08-09 N Spine, Inc. Method and apparatus for flexible fixation of a spine
US7632293B2 (en) 2003-09-29 2009-12-15 Synthes Usa, Llc Dynamic damping element for two bones
US20060264940A1 (en) * 2003-09-29 2006-11-23 Stephan Hartmann Dynamic damping element for two bones
US20050124991A1 (en) * 2003-12-05 2005-06-09 Tae-Ahn Jahng Method and apparatus for flexible fixation of a spine
US7763052B2 (en) 2003-12-05 2010-07-27 N Spine, Inc. Method and apparatus for flexible fixation of a spine
US8100915B2 (en) 2004-02-27 2012-01-24 Jackson Roger P Orthopedic implant rod reduction tool set and method
US8394133B2 (en) 2004-02-27 2013-03-12 Roger P. Jackson Dynamic fixation assemblies with inner core and outer coil-like member
US8162948B2 (en) 2004-02-27 2012-04-24 Jackson Roger P Orthopedic implant rod reduction tool set and method
US8377067B2 (en) 2004-02-27 2013-02-19 Roger P. Jackson Orthopedic implant rod reduction tool set and method
US8066739B2 (en) 2004-02-27 2011-11-29 Jackson Roger P Tool system for dynamic spinal implants
US8894657B2 (en) 2004-02-27 2014-11-25 Roger P. Jackson Tool system for dynamic spinal implants
US9050139B2 (en) 2004-02-27 2015-06-09 Roger P. Jackson Orthopedic implant rod reduction tool set and method
US7766915B2 (en) 2004-02-27 2010-08-03 Jackson Roger P Dynamic fixation assemblies with inner core and outer coil-like member
US9055978B2 (en) 2004-02-27 2015-06-16 Roger P. Jackson Orthopedic implant rod reduction tool set and method
US20080091213A1 (en) * 2004-02-27 2008-04-17 Jackson Roger P Tool system for dynamic spinal implants
US20110077692A1 (en) * 2004-02-27 2011-03-31 Jackson Roger P Dynamic spinal stabilization assemblies, tool set and method
US8292892B2 (en) 2004-02-27 2012-10-23 Jackson Roger P Orthopedic implant rod reduction tool set and method
US20060111715A1 (en) * 2004-02-27 2006-05-25 Jackson Roger P Dynamic stabilization assemblies, tool set and method
US9918751B2 (en) 2004-02-27 2018-03-20 Roger P. Jackson Tool system for dynamic spinal implants
US9216039B2 (en) 2004-02-27 2015-12-22 Roger P. Jackson Dynamic spinal stabilization assemblies, tool set and method
US8900272B2 (en) 2004-02-27 2014-12-02 Roger P Jackson Dynamic fixation assemblies with inner core and outer coil-like member
US7862587B2 (en) 2004-02-27 2011-01-04 Jackson Roger P Dynamic stabilization assemblies, tool set and method
US20050216017A1 (en) * 2004-03-09 2005-09-29 Louie Fielding Spinal implant and method for restricting spinal flexion
US20080009866A1 (en) * 2004-03-09 2008-01-10 Todd Alamin Methods and systems for constraint of spinous processes with attachment
US9149304B2 (en) 2004-03-09 2015-10-06 The Board Of Trustees Of The Leland Sanford Junior University Methods and systems for constraint of spinous processes with attachment
US7458981B2 (en) 2004-03-09 2008-12-02 The Board Of Trustees Of The Leland Stanford Junior University Spinal implant and method for restricting spinal flexion
US20090198282A1 (en) * 2004-03-09 2009-08-06 Louis Fielding Spinal implant and method for restricting spinal flexion
US8216275B2 (en) 2004-03-09 2012-07-10 The Board Of Trustees Of The Leland Stanford Junior University Spinal implant and method for restricting spinal flexion
US8105363B2 (en) 2004-03-09 2012-01-31 The Board Of Trustees Of The Leland Stanford Junior University Spinal implant and method for restricting spinal flexion
US8523904B2 (en) 2004-03-09 2013-09-03 The Board Of Trustees Of The Leland Stanford Junior University Methods and systems for constraint of spinous processes with attachment
US8486110B2 (en) 2004-03-09 2013-07-16 The Board Of Trustees Of The Leland Stanford Junior University Spinal implant and method for restricting spinal flexion
US20050251170A1 (en) * 2004-05-07 2005-11-10 Ethicon Endo-Surgery, Inc. Instrument for effecting anastomosis of respective tissues defining two body lumens
US8216276B2 (en) 2004-05-21 2012-07-10 Warsaw Orthopedic, Inc. Interspinous spacer
US20050261768A1 (en) * 2004-05-21 2005-11-24 Trieu Hai H Interspinous spacer
US20060247637A1 (en) * 2004-08-09 2006-11-02 Dennis Colleran System and method for dynamic skeletal stabilization
US7854752B2 (en) 2004-08-09 2010-12-21 Theken Spine, Llc System and method for dynamic skeletal stabilization
US20080046087A1 (en) * 2004-09-23 2008-02-21 Zucherman James F Interspinous process implant including a binder and method of implantation
US20060064165A1 (en) * 2004-09-23 2006-03-23 St. Francis Medical Technologies, Inc. Interspinous process implant including a binder and method of implantation
US20060064166A1 (en) * 2004-09-23 2006-03-23 St. Francis Medical Technologies, Inc. Interspinous process implant including a binder and method of implantation
US7909853B2 (en) 2004-09-23 2011-03-22 Kyphon Sarl Interspinous process implant including a binder and method of implantation
US8012209B2 (en) 2004-09-23 2011-09-06 Kyphon Sarl Interspinous process implant including a binder, binder aligner and method of implantation
US20070276500A1 (en) * 2004-09-23 2007-11-29 St. Francis Medical Technologies, Inc. Interspinous process implant including a binder, binder aligner and method of implantation
US8845649B2 (en) 2004-09-24 2014-09-30 Roger P. Jackson Spinal fixation tool set and method for rod reduction and fastener insertion
US7985244B2 (en) 2004-09-30 2011-07-26 Depuy Spine, Inc. Posterior dynamic stabilizer devices
US20060084976A1 (en) * 2004-09-30 2006-04-20 Depuy Spine, Inc. Posterior stabilization systems and methods
US8092496B2 (en) 2004-09-30 2012-01-10 Depuy Spine, Inc. Methods and devices for posterior stabilization
US20070233095A1 (en) * 2004-10-07 2007-10-04 Schlaepfer Fridolin J Device for dynamic stabilization of bones or bone fragments
US20110087290A1 (en) * 2004-10-07 2011-04-14 Fridolin Johannes Schlaepfer Device for dynamic stabilization of bones or bone fragments
US7867256B2 (en) 2004-10-07 2011-01-11 Synthes Usa, Llc Device for dynamic stabilization of bones or bone fragments
US20060085076A1 (en) * 2004-10-15 2006-04-20 Manoj Krishna Posterior spinal arthroplasty-development of a new posteriorly inserted artificial disc and an artificial facet joint
US8852235B2 (en) 2004-10-15 2014-10-07 Spinadyne, Inc. Posteriorly inserted artificial disc and an artificial facet joint
US20080033562A1 (en) * 2004-10-15 2008-02-07 Disc Motion Technologies, Inc. Posteriorly inserted artificial disc and an artificial facet joint
US20060089717A1 (en) * 2004-10-15 2006-04-27 Manoj Krishna Spinal prosthesis and facet joint prosthesis
US9956011B2 (en) 2004-10-20 2018-05-01 Vertiflex, Inc. Interspinous spacer
US8551142B2 (en) 2004-10-20 2013-10-08 Exactech, Inc. Methods for stabilization of bone structures
US20060084984A1 (en) * 2004-10-20 2006-04-20 The Board Of Trustees For The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8628574B2 (en) 2004-10-20 2014-01-14 Vertiflex, Inc. Systems and methods for posterior dynamic stabilization of the spine
US8075595B2 (en) 2004-10-20 2011-12-13 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US9572603B2 (en) 2004-10-20 2017-02-21 Vertiflex, Inc. Interspinous spacer
US20070276370A1 (en) * 2004-10-20 2007-11-29 Vertiflex, Inc. Minimally invasive tooling for delivery of interspinous spacer
US20110106160A1 (en) * 2004-10-20 2011-05-05 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8425559B2 (en) 2004-10-20 2013-04-23 Vertiflex, Inc. Systems and methods for posterior dynamic stabilization of the spine
US8409282B2 (en) 2004-10-20 2013-04-02 Vertiflex, Inc. Systems and methods for posterior dynamic stabilization of the spine
US8123782B2 (en) 2004-10-20 2012-02-28 Vertiflex, Inc. Interspinous spacer
US8267969B2 (en) 2004-10-20 2012-09-18 Exactech, Inc. Screw systems and methods for use in stabilization of bone structures
US8123807B2 (en) 2004-10-20 2012-02-28 Vertiflex, Inc. Systems and methods for posterior dynamic stabilization of the spine
US20060122620A1 (en) * 2004-10-20 2006-06-08 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for stabilizing the motion or adjusting the position of the spine
US9532812B2 (en) 2004-10-20 2017-01-03 Vertiflex, Inc. Interspinous spacer
US20060084983A1 (en) * 2004-10-20 2006-04-20 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US20080287997A1 (en) * 2004-10-20 2008-11-20 Moti Altarac Interspinous spacer
US8317864B2 (en) 2004-10-20 2012-11-27 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8292922B2 (en) 2004-10-20 2012-10-23 Vertiflex, Inc. Interspinous spacer
US20080294263A1 (en) * 2004-10-20 2008-11-27 Moti Altarac Interspinous spacer
US9861398B2 (en) 2004-10-20 2018-01-09 Vertiflex, Inc. Interspinous spacer
US9877749B2 (en) 2004-10-20 2018-01-30 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8277488B2 (en) 2004-10-20 2012-10-02 Vertiflex, Inc. Interspinous spacer
US20110144701A1 (en) * 2004-10-20 2011-06-16 Exactech, Inc. Methods for stabilization of bone structures
US9445843B2 (en) 2004-10-20 2016-09-20 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US20070100341A1 (en) * 2004-10-20 2007-05-03 Reglos Joey C Systems and methods for stabilization of bone structures
US8273108B2 (en) 2004-10-20 2012-09-25 Vertiflex, Inc. Interspinous spacer
US20070167949A1 (en) * 2004-10-20 2007-07-19 Moti Altarac Screw systems and methods for use in stabilization of bone structures
US8128662B2 (en) 2004-10-20 2012-03-06 Vertiflex, Inc. Minimally invasive tooling for delivery of interspinous spacer
US20060084982A1 (en) * 2004-10-20 2006-04-20 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US9393055B2 (en) 2004-10-20 2016-07-19 Vertiflex, Inc. Spacer insertion instrument
US9314279B2 (en) 2004-10-20 2016-04-19 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US9039742B2 (en) 2004-10-20 2015-05-26 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US9211146B2 (en) 2004-10-20 2015-12-15 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8900271B2 (en) 2004-10-20 2014-12-02 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US9161783B2 (en) 2004-10-20 2015-10-20 Vertiflex, Inc. Interspinous spacer
US20090222043A1 (en) * 2004-10-20 2009-09-03 Moti Altarac Interspinous process spacer instrument system with deployment indicator
US7998175B2 (en) 2004-10-20 2011-08-16 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US9155570B2 (en) 2004-10-20 2015-10-13 Vertiflex, Inc. Interspinous spacer
US9155572B2 (en) 2004-10-20 2015-10-13 Vertiflex, Inc. Minimally invasive tooling for delivery of interspinous spacer
US8012207B2 (en) 2004-10-20 2011-09-06 Vertiflex, Inc. Systems and methods for posterior dynamic stabilization of the spine
US8945183B2 (en) 2004-10-20 2015-02-03 Vertiflex, Inc. Interspinous process spacer instrument system with deployment indicator
US20060084985A1 (en) * 2004-10-20 2006-04-20 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8167944B2 (en) 2004-10-20 2012-05-01 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8162985B2 (en) 2004-10-20 2012-04-24 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8025680B2 (en) 2004-10-20 2011-09-27 Exactech, Inc. Systems and methods for posterior dynamic stabilization of the spine
US9125692B2 (en) 2004-10-20 2015-09-08 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8613747B2 (en) 2004-10-20 2013-12-24 Vertiflex, Inc. Spacer insertion instrument
US9119680B2 (en) 2004-10-20 2015-09-01 Vertiflex, Inc. Interspinous spacer
US20060084987A1 (en) * 2004-10-20 2006-04-20 Kim Daniel H Systems and methods for posterior dynamic stabilization of the spine
US7935134B2 (en) 2004-10-20 2011-05-03 Exactech, Inc. Systems and methods for stabilization of bone structures
US9023084B2 (en) 2004-10-20 2015-05-05 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for stabilizing the motion or adjusting the position of the spine
US9283005B2 (en) 2004-10-20 2016-03-15 Vertiflex, Inc. Systems and methods for posterior dynamic stabilization of the spine
US8152837B2 (en) 2004-10-20 2012-04-10 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for posterior dynamic stabilization of the spine
US8864828B2 (en) 2004-10-20 2014-10-21 Vertiflex, Inc. Interspinous spacer
US8673009B2 (en) 2004-10-21 2014-03-18 Spinadyne, Inc. Spinal prosthesis and facet joint prosthesis
US20060265074A1 (en) * 2004-10-21 2006-11-23 Manoj Krishna Posterior spinal arthroplasty-development of a new posteriorly inserted artificial disc, a new anteriorly inserted artifical disc and an artificial facet joint
US8673008B2 (en) 2004-10-21 2014-03-18 Spinadyne, Inc. Posterior spinal arthroplasty system
US20060155279A1 (en) * 2004-10-28 2006-07-13 Axial Biotech, Inc. Apparatus and method for concave scoliosis expansion
US9743957B2 (en) 2004-11-10 2017-08-29 Roger P. Jackson Polyaxial bone screw with shank articulation pressure insert and method
US9211150B2 (en) 2004-11-23 2015-12-15 Roger P. Jackson Spinal fixation tool set and method
US8273089B2 (en) 2004-11-23 2012-09-25 Jackson Roger P Spinal fixation tool set and method
US9629669B2 (en) 2004-11-23 2017-04-25 Roger P. Jackson Spinal fixation tool set and method
US8591515B2 (en) 2004-11-23 2013-11-26 Roger P. Jackson Spinal fixation tool set and method
US8152810B2 (en) 2004-11-23 2012-04-10 Jackson Roger P Spinal fixation tool set and method
US20060149229A1 (en) * 2004-12-30 2006-07-06 Kwak Seungkyu Daniel Artificial facet joint
US20060271046A1 (en) * 2004-12-30 2006-11-30 Kwak Seungkyu Daniel Facet joint replacement
US7766940B2 (en) 2004-12-30 2010-08-03 Depuy Spine, Inc. Posterior stabilization system
US8070783B2 (en) 2004-12-30 2011-12-06 Depuy Spine, Inc. Facet joint replacement
US7896906B2 (en) 2004-12-30 2011-03-01 Depuy Spine, Inc. Artificial facet joint
US8709043B2 (en) 2004-12-30 2014-04-29 Depuy Spine, Inc. Artificial facet joint
US7799054B2 (en) 2004-12-30 2010-09-21 Depuy Spine, Inc. Facet joint replacement
US20080058935A1 (en) * 2005-02-17 2008-03-06 Malandain Hugues F Percutaneous spinal implants and methods
US8097018B2 (en) 2005-02-17 2012-01-17 Kyphon Sarl Percutaneous spinal implants and methods
US20070282442A1 (en) * 2005-02-17 2007-12-06 Malandain Hugues F Percutaneous spinal implants and methods
US8092459B2 (en) 2005-02-17 2012-01-10 Kyphon Sarl Percutaneous spinal implants and methods
US20070282340A1 (en) * 2005-02-17 2007-12-06 Malandain Hugues F Percutaneous spinal implants and methods
US20070276493A1 (en) * 2005-02-17 2007-11-29 Malandain Hugues F Percutaneous spinal implants and methods
US8096994B2 (en) 2005-02-17 2012-01-17 Kyphon Sarl Percutaneous spinal implants and methods
US8100943B2 (en) 2005-02-17 2012-01-24 Kyphon Sarl Percutaneous spinal implants and methods
US20070299526A1 (en) * 2005-02-17 2007-12-27 Malandain Hugues F Percutaneous spinal implants and methods
US20070276372A1 (en) * 2005-02-17 2007-11-29 Malandain Hugues F Percutaneous Spinal Implants and Methods
US20070276373A1 (en) * 2005-02-17 2007-11-29 Malandain Hugues F Percutaneous Spinal Implants and Methods
US8057513B2 (en) 2005-02-17 2011-11-15 Kyphon Sarl Percutaneous spinal implants and methods
US20080027433A1 (en) * 2005-02-17 2008-01-31 Kohm Andrew C Percutaneous spinal implants and methods
US20070049934A1 (en) * 2005-02-17 2007-03-01 Edidin Avram A Percutaneous spinal implants and methods
US8029567B2 (en) 2005-02-17 2011-10-04 Kyphon Sarl Percutaneous spinal implants and methods
US7927354B2 (en) 2005-02-17 2011-04-19 Kyphon Sarl Percutaneous spinal implants and methods
US20080039944A1 (en) * 2005-02-17 2008-02-14 Malandain Hugues F Percutaneous Spinal Implants and Methods
US8147516B2 (en) 2005-02-17 2012-04-03 Kyphon Sarl Percutaneous spinal implants and methods
US8043335B2 (en) 2005-02-17 2011-10-25 Kyphon Sarl Percutaneous spinal implants and methods
US20070265623A1 (en) * 2005-02-17 2007-11-15 Malandain Hugues F Percutaneous Spinal Implants and Methods
US20070049935A1 (en) * 2005-02-17 2007-03-01 Edidin Avram A Percutaneous spinal implants and methods
US20070055237A1 (en) * 2005-02-17 2007-03-08 Edidin Avram A Percutaneous spinal implants and methods
US20080132952A1 (en) * 2005-02-17 2008-06-05 Malandain Hugues F Percutaneous spinal implants and methods
US8454693B2 (en) 2005-02-17 2013-06-04 Kyphon Sarl Percutaneous spinal implants and methods
US20070225706A1 (en) * 2005-02-17 2007-09-27 Clark Janna G Percutaneous spinal implants and methods
US8038698B2 (en) 2005-02-17 2011-10-18 Kphon Sarl Percutaneous spinal implants and methods
US8034080B2 (en) 2005-02-17 2011-10-11 Kyphon Sarl Percutaneous spinal implants and methods
US20080071376A1 (en) * 2005-02-17 2008-03-20 Kohm Andrew C Percutaneous spinal implants and methods
US8029549B2 (en) 2005-02-17 2011-10-04 Kyphon Sarl Percutaneous spinal implants and methods
US20080288078A1 (en) * 2005-02-17 2008-11-20 Kohm Andrew C Percutaneous spinal implants and methods
US20110144697A1 (en) * 2005-02-17 2011-06-16 Kyphon Sarl Percutaneous spinal implants and methods
US20080058937A1 (en) * 2005-02-17 2008-03-06 Malandain Hugues F Percutaneous spinal implants and methods
US7988709B2 (en) 2005-02-17 2011-08-02 Kyphon Sarl Percutaneous spinal implants and methods
US8167890B2 (en) 2005-02-17 2012-05-01 Kyphon Sarl Percutaneous spinal implants and methods
US20060184247A1 (en) * 2005-02-17 2006-08-17 Edidin Avram A Percutaneous spinal implants and methods
US20080051894A1 (en) * 2005-02-17 2008-02-28 Malandain Hugues F Percutaneous spinal implants and methods
US20060184248A1 (en) * 2005-02-17 2006-08-17 Edidin Avram A Percutaneous spinal implants and methods
US8007521B2 (en) 2005-02-17 2011-08-30 Kyphon Sarl Percutaneous spinal implants and methods
US20080051893A1 (en) * 2005-02-17 2008-02-28 Malandain Hugues F Percutaneous spinal implants and methods
US8679161B2 (en) 2005-02-17 2014-03-25 Warsaw Orthopedic, Inc. Percutaneous spinal implants and methods
US7998174B2 (en) 2005-02-17 2011-08-16 Kyphon Sarl Percutaneous spinal implants and methods
US20080058934A1 (en) * 2005-02-17 2008-03-06 Malandain Hugues F Percutaneous spinal implants and methods
US7993342B2 (en) 2005-02-17 2011-08-09 Kyphon Sarl Percutaneous spinal implants and methods
US7998208B2 (en) 2005-02-17 2011-08-16 Kyphon Sarl Percutaneous spinal implants and methods
US20080058936A1 (en) * 2005-02-17 2008-03-06 Malandain Hugues F Percutaneous spinal implants and methods
US8221458B2 (en) 2005-02-17 2012-07-17 Kyphon Sarl Percutaneous spinal implants and methods
US8096995B2 (en) 2005-02-17 2012-01-17 Kyphon Sarl Percutaneous spinal implants and methods
US8157841B2 (en) 2005-02-17 2012-04-17 Kyphon Sarl Percutaneous spinal implants and methods
US8974499B2 (en) * 2005-02-22 2015-03-10 Stryker Spine Apparatus and method for dynamic vertebral stabilization
US20100010544A1 (en) * 2005-02-22 2010-01-14 Stryker Spine Apparatus and method for dynamic vertebral stabilization
US20060189984A1 (en) * 2005-02-22 2006-08-24 Medicinelodge, Inc. Apparatus and method for dynamic vertebral stabilization
US20090099607A1 (en) * 2005-02-22 2009-04-16 Stryker Spine Apparatus and method for dynamic vertebral stabilization
US9414863B2 (en) 2005-02-22 2016-08-16 Roger P. Jackson Polyaxial bone screw with spherical capture, compression insert and alignment and retention structures
US9949762B2 (en) 2005-02-22 2018-04-24 Stryker European Holdings I, Llc Apparatus and method for dynamic vertebral stabilization
US9486244B2 (en) 2005-02-22 2016-11-08 Stryker European Holdings I, Llc Apparatus and method for dynamic vertebral stabilization
US8226687B2 (en) 2005-02-22 2012-07-24 Stryker Spine Apparatus and method for dynamic vertebral stabilization
US20060229612A1 (en) * 2005-03-03 2006-10-12 Accin Corporation Methods and apparatus for vertebral stabilization using sleeved springs
US7556639B2 (en) 2005-03-03 2009-07-07 Accelerated Innovation, Llc Methods and apparatus for vertebral stabilization using sleeved springs
US20060212033A1 (en) * 2005-03-03 2006-09-21 Accin Corporation Vertebral stabilization using flexible rods
US20060202242A1 (en) * 2005-03-09 2006-09-14 Sony Corporation Solid-state imaging device
US20080177272A1 (en) * 2005-03-21 2008-07-24 Zucherman James F Interspinous process implant having deployable wing and method of implantation
US8273107B2 (en) 2005-03-21 2012-09-25 Kyphon Sarl Interspinous process implant having a thread-shaped wing and method of implantation
US20070010813A1 (en) * 2005-03-21 2007-01-11 St. Francis Medical Technologies, Inc. Interspinous process implant having deployable wing and method of implantation
US8591546B2 (en) 2005-03-21 2013-11-26 Warsaw Orthopedic, Inc. Interspinous process implant having a thread-shaped wing and method of implantation
US20060265066A1 (en) * 2005-03-21 2006-11-23 St. Francis Medical Technologies, Inc. Interspinous process implant having a thread-shaped wing and method of implantation
US8147548B2 (en) 2005-03-21 2012-04-03 Kyphon Sarl Interspinous process implant having a thread-shaped wing and method of implantation
US20080046086A1 (en) * 2005-03-21 2008-02-21 Zucherman James F Interspinous process implant having a thread-shaped wing and method of implantation
US7749252B2 (en) 2005-03-21 2010-07-06 Kyphon Sarl Interspinous process implant having deployable wing and method of implantation
US20060264938A1 (en) * 2005-03-21 2006-11-23 St. Francis Medical Technologies, Inc. Interspinous process implant having deployable wing and method of implantation
US7931674B2 (en) 2005-03-21 2011-04-26 Kyphon Sarl Interspinous process implant having deployable wing and method of implantation
US20060241757A1 (en) * 2005-03-31 2006-10-26 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of manufacturing same
US20060224159A1 (en) * 2005-03-31 2006-10-05 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US20100042150A1 (en) * 2005-03-31 2010-02-18 Warsaw Orthopedic, Inc. Intervertebral prosthetic device for spinal stabilization and method of manufacturing same
US8066742B2 (en) 2005-03-31 2011-11-29 Warsaw Orthopedic, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US7862590B2 (en) 2005-04-08 2011-01-04 Warsaw Orthopedic, Inc. Interspinous process spacer
US20060241614A1 (en) * 2005-04-12 2006-10-26 Sdgi Holdings, Inc. Implants and methods for posterior dynamic stabilization of a spinal motion segment
US20060241613A1 (en) * 2005-04-12 2006-10-26 Sdgi Holdings, Inc. Implants and methods for inter-transverse process dynamic stabilization of a spinal motion segment
US8034079B2 (en) 2005-04-12 2011-10-11 Warsaw Orthopedic, Inc. Implants and methods for posterior dynamic stabilization of a spinal motion segment
US7780709B2 (en) 2005-04-12 2010-08-24 Warsaw Orthopedic, Inc. Implants and methods for inter-transverse process dynamic stabilization of a spinal motion segment
US20060235387A1 (en) * 2005-04-15 2006-10-19 Sdgi Holdings, Inc. Transverse process/laminar spacer
US7789898B2 (en) 2005-04-15 2010-09-07 Warsaw Orthopedic, Inc. Transverse process/laminar spacer
US7959652B2 (en) 2005-04-18 2011-06-14 Kyphon Sarl Interspinous process implant having deployable wings and method of implantation
US20060271049A1 (en) * 2005-04-18 2006-11-30 St. Francis Medical Technologies, Inc. Interspinous process implant having deployable wings and method of implantation
US20080045958A1 (en) * 2005-04-18 2008-02-21 Zucherman James F Interspinous process implant having deployable wings and method of implantation
US8109972B2 (en) 2005-04-18 2012-02-07 Kyphon Sarl Interspinous process implant having deployable wings and method of implantation
US20080046085A1 (en) * 2005-04-18 2008-02-21 Zucherman James F Interspinous process implant having deployable wings and method of implantation
US8128702B2 (en) 2005-04-18 2012-03-06 Kyphon Sarl Interspinous process implant having deployable wings and method of implantation
US20060247640A1 (en) * 2005-04-29 2006-11-02 Sdgi Holdings, Inc. Spinous process stabilization devices and methods
US8226653B2 (en) 2005-04-29 2012-07-24 Warsaw Orthopedic, Inc. Spinous process stabilization devices and methods
US7727233B2 (en) 2005-04-29 2010-06-01 Warsaw Orthopedic, Inc. Spinous process stabilization devices and methods
US20100211101A1 (en) * 2005-04-29 2010-08-19 Warsaw Orthopedic, Inc. Spinous Process Stabilization Devices and Methods
US20060282080A1 (en) * 2005-06-08 2006-12-14 Accin Corporation Vertebral facet stabilizer
WO2007019894A1 (en) * 2005-06-22 2007-02-22 Tutogen Medical Gmbh Vertebral implant made from bone material for relief of a narrowed vertebral channel
US20100217320A1 (en) * 2005-06-22 2010-08-26 Tutogen Medical Gmbh Vertebral implant made from bone material for relief of a narrowed vertebral channel
US7846186B2 (en) 2005-06-28 2010-12-07 Kyphon SÀRL Equipment for surgical treatment of two vertebrae
US20070239159A1 (en) * 2005-07-22 2007-10-11 Vertiflex, Inc. Systems and methods for stabilization of bone structures
US8523865B2 (en) 2005-07-22 2013-09-03 Exactech, Inc. Tissue splitter
US20070043359A1 (en) * 2005-07-22 2007-02-22 Moti Altarac Systems and methods for stabilization of bone structures
US8226690B2 (en) 2005-07-22 2012-07-24 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for stabilization of bone structures
US7811309B2 (en) 2005-07-26 2010-10-12 Applied Spine Technologies, Inc. Dynamic spine stabilization device with travel-limiting functionality
US20070043356A1 (en) * 2005-07-26 2007-02-22 Timm Jens P Dynamic spine stabilization device with travel-limiting functionality
US8613760B2 (en) 2005-09-30 2013-12-24 Roger P. Jackson Dynamic stabilization connecting member with slitted core and outer sleeve
US8696711B2 (en) 2005-09-30 2014-04-15 Roger P. Jackson Polyaxial bone anchor assembly with one-piece closure, pressure insert and plastic elongate member
US8353932B2 (en) 2005-09-30 2013-01-15 Jackson Roger P Polyaxial bone anchor assembly with one-piece closure, pressure insert and plastic elongate member
US8292926B2 (en) 2005-09-30 2012-10-23 Jackson Roger P Dynamic stabilization connecting member with elastic core and outer sleeve
US8105368B2 (en) 2005-09-30 2012-01-31 Jackson Roger P Dynamic stabilization connecting member with slitted core and outer sleeve
US8591560B2 (en) 2005-09-30 2013-11-26 Roger P. Jackson Dynamic stabilization connecting member with elastic core and outer sleeve
US20070093815A1 (en) * 2005-10-11 2007-04-26 Callahan Ronald Ii Dynamic spinal stabilizer
US20070093814A1 (en) * 2005-10-11 2007-04-26 Callahan Ronald Ii Dynamic spinal stabilization systems
US20070093813A1 (en) * 2005-10-11 2007-04-26 Callahan Ronald Ii Dynamic spinal stabilizer
US8357181B2 (en) 2005-10-27 2013-01-22 Warsaw Orthopedic, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US20070100340A1 (en) * 2005-10-27 2007-05-03 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US8623059B2 (en) 2005-10-31 2014-01-07 Stryker Spine System and method for dynamic vertebral stabilization
US8137385B2 (en) 2005-10-31 2012-03-20 Stryker Spine System and method for dynamic vertebral stabilization
US8109973B2 (en) 2005-10-31 2012-02-07 Stryker Spine Method for dynamic vertebral stabilization
US8529603B2 (en) 2005-10-31 2013-09-10 Stryker Spine System and method for dynamic vertebral stabilization
US10004539B2 (en) 2005-10-31 2018-06-26 Stryker European Holdings I, Llc System and method for dynamic vertebral stabilization
US9445846B2 (en) 2005-10-31 2016-09-20 Stryker European Holdings I, Llc System and method for dynamic vertebral stabilization
US7862591B2 (en) 2005-11-10 2011-01-04 Warsaw Orthopedic, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US20070123861A1 (en) * 2005-11-10 2007-05-31 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US8545538B2 (en) 2005-12-19 2013-10-01 M. Samy Abdou Devices and methods for inter-vertebral orthopedic device placement
US20070168038A1 (en) * 2006-01-13 2007-07-19 Sdgi Holdings, Inc. Materials, devices and methods for treating multiple spinal regions including the interbody region
US20070173820A1 (en) * 2006-01-13 2007-07-26 Sdgi Holdings, Inc. Materials, devices, and methods for treating multiple spinal regions including the anterior region
US8083795B2 (en) 2006-01-18 2011-12-27 Warsaw Orthopedic, Inc. Intervertebral prosthetic device for spinal stabilization and method of manufacturing same
US20070167945A1 (en) * 2006-01-18 2007-07-19 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of manufacturing same
US8029550B2 (en) 2006-01-18 2011-10-04 Warsaw Orthopedic, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US20070173823A1 (en) * 2006-01-18 2007-07-26 Sdgi Holdings, Inc. Intervertebral prosthetic device for spinal stabilization and method of implanting same
US7815663B2 (en) 2006-01-27 2010-10-19 Warsaw Orthopedic, Inc. Vertebral rods and methods of use
US20070191838A1 (en) * 2006-01-27 2007-08-16 Sdgi Holdings, Inc. Interspinous devices and methods of use
US8348977B2 (en) 2006-01-27 2013-01-08 Warsaw Orthopedic, Inc. Artificial spinous process for the sacrum and methods of use
US20070191834A1 (en) * 2006-01-27 2007-08-16 Sdgi Holdings, Inc. Artificial spinous process for the sacrum and methods of use
US8216279B2 (en) 2006-01-27 2012-07-10 Warsaw Orthopedic, Inc. Spinal implant kits with multiple interchangeable modules
US20100145387A1 (en) * 2006-01-27 2010-06-10 Warsaw Orthopedic, Inc. Spinal implants including a sensor and methods of use
US20100268277A1 (en) * 2006-01-27 2010-10-21 Warsaw Orthopedic, Inc. Artificial spinous process for the sacrum and methods of use
US7691130B2 (en) 2006-01-27 2010-04-06 Warsaw Orthopedic, Inc. Spinal implants including a sensor and methods of use
US20070191953A1 (en) * 2006-01-27 2007-08-16 Sdgi Holdings, Inc. Intervertebral implants and methods of use
US7578849B2 (en) 2006-01-27 2009-08-25 Warsaw Orthopedic, Inc. Intervertebral implants and methods of use
US7682376B2 (en) 2006-01-27 2010-03-23 Warsaw Orthopedic, Inc. Interspinous devices and methods of use
US20070191832A1 (en) * 2006-01-27 2007-08-16 Sdgi Holdings, Inc. Vertebral rods and methods of use
US9144439B2 (en) 2006-01-27 2015-09-29 Warsaw Orthopedic, Inc. Vertebral rods and methods of use
US8414619B2 (en) 2006-01-27 2013-04-09 Warsaw Orthopedic, Inc. Vertebral rods and methods of use
US20070191837A1 (en) * 2006-01-27 2007-08-16 Sdgi Holdings, Inc. Interspinous devices and methods of use
US7837711B2 (en) 2006-01-27 2010-11-23 Warsaw Orthopedic, Inc. Artificial spinous process for the sacrum and methods of use
US8029545B2 (en) 2006-02-07 2011-10-04 Warsaw Orthopedic Inc. Articulating connecting member and anchor systems for spinal stabilization
US20070198014A1 (en) * 2006-02-07 2007-08-23 Sdgi Holdings, Inc. Articulating connecting member and anchor systems for spinal stabilization
US20070233068A1 (en) * 2006-02-22 2007-10-04 Sdgi Holdings, Inc. Intervertebral prosthetic assembly for spinal stabilization and method of implanting same
US8262698B2 (en) 2006-03-16 2012-09-11 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US20070233074A1 (en) * 2006-03-16 2007-10-04 Sdgi Holdings, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US7976549B2 (en) 2006-03-23 2011-07-12 Theken Spine, Llc Instruments for delivering spinal implants
US20070225810A1 (en) * 2006-03-23 2007-09-27 Dennis Colleran Flexible cage spinal implant
US20070233094A1 (en) * 2006-03-29 2007-10-04 Dennis Colleran Dynamic motion spinal stabilization system
US8025681B2 (en) 2006-03-29 2011-09-27 Theken Spine, Llc Dynamic motion spinal stabilization system
US20070233076A1 (en) * 2006-03-31 2007-10-04 Sdgi Holdings, Inc. Methods and instruments for delivering interspinous process spacers
US7985246B2 (en) 2006-03-31 2011-07-26 Warsaw Orthopedic, Inc. Methods and instruments for delivering interspinous process spacers
US20090275982A1 (en) * 2006-04-13 2009-11-05 Jean Taylor Device for treating vertebrae, including an interspinous implant
US20070270959A1 (en) * 2006-04-18 2007-11-22 Sdgi Holdings, Inc. Arthroplasty device
US20070270814A1 (en) * 2006-04-20 2007-11-22 Sdgi Holdings, Inc. Vertebral stabilizer
US7942905B2 (en) * 2006-04-20 2011-05-17 Warsaw Orthopedic, Inc. Vertebral stabilizer
US20070288012A1 (en) * 2006-04-21 2007-12-13 Dennis Colleran Dynamic motion spinal stabilization system and device
US8118844B2 (en) 2006-04-24 2012-02-21 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US20070270823A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Multi-chamber expandable interspinous process brace
US8348978B2 (en) 2006-04-28 2013-01-08 Warsaw Orthopedic, Inc. Interosteotic implant
US8048118B2 (en) 2006-04-28 2011-11-01 Warsaw Orthopedic, Inc. Adjustable interspinous process brace
US8221465B2 (en) 2006-04-28 2012-07-17 Warsaw Orthopedic, Inc. Multi-chamber expandable interspinous process spacer
US20070270828A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Interspinous process brace
US8105357B2 (en) 2006-04-28 2012-01-31 Warsaw Orthopedic, Inc. Interspinous process brace
US20070270826A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Interosteotic implant
US20070270829A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Molding device for an expandable interspinous process implant
US20100249841A1 (en) * 2006-04-28 2010-09-30 Warsaw Orthopedic, Inc. Multi-chamber expandable interspinous process spacer
US7846185B2 (en) 2006-04-28 2010-12-07 Warsaw Orthopedic, Inc. Expandable interspinous process implant and method of installing same
US20070270825A1 (en) * 2006-04-28 2007-11-22 Sdgi Holdings, Inc. Expandable interspinous process implant and method of installing same
US8252031B2 (en) 2006-04-28 2012-08-28 Warsaw Orthopedic, Inc. Molding device for an expandable interspinous process implant
US20070270824A1 (en) * 2006-04-28 2007-11-22 Warsaw Orthopedic, Inc. Interspinous process brace
US20070270834A1 (en) * 2006-05-04 2007-11-22 Sdgi Holdings, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US8062337B2 (en) 2006-05-04 2011-11-22 Warsaw Orthopedic, Inc. Expandable device for insertion between anatomical structures and a procedure utilizing same
US8690919B2 (en) 2006-05-23 2014-04-08 Warsaw Orthopedic, Inc. Surgical spacer with shape control
US20070276496A1 (en) * 2006-05-23 2007-11-29 Sdgi Holdings, Inc. Surgical spacer with shape control
US20070276368A1 (en) * 2006-05-23 2007-11-29 Sdgi Holdings, Inc. Systems and methods for adjusting properties of a spinal implant
US8147517B2 (en) 2006-05-23 2012-04-03 Warsaw Orthopedic, Inc. Systems and methods for adjusting properties of a spinal implant
US20100114320A1 (en) * 2006-05-23 2010-05-06 Warsaw Orthopedic, Inc., An Indiana Corporation Surgical spacer with shape control
US20070276369A1 (en) * 2006-05-26 2007-11-29 Sdgi Holdings, Inc. In vivo-customizable implant
US20080228227A1 (en) * 2006-06-08 2008-09-18 Disc Motion Technologies, Inc. Dynamic connector for spinal device
US8147518B2 (en) 2006-06-08 2012-04-03 Spinadyne, Inc. Dynamic connector for spinal device
US20070288009A1 (en) * 2006-06-08 2007-12-13 Steven Brown Dynamic spinal stabilization device
US20080195154A1 (en) * 2006-06-08 2008-08-14 Disc Motion Technologies, Inc. Dynamic spinal stabilization device
US20070288094A1 (en) * 2006-06-08 2007-12-13 Manoj Krishna System and method for lumbar arthroplasty
US8858600B2 (en) 2006-06-08 2014-10-14 Spinadyne, Inc. Dynamic spinal stabilization device
US7905906B2 (en) 2006-06-08 2011-03-15 Disc Motion Technologies, Inc. System and method for lumbar arthroplasty
US8449576B2 (en) 2006-06-28 2013-05-28 DePuy Synthes Products, LLC Dynamic fixation system
US20100069964A1 (en) * 2006-06-28 2010-03-18 Beat Lechmann Dynamic fixation system
US8048119B2 (en) 2006-07-20 2011-11-01 Warsaw Orthopedic, Inc. Apparatus for insertion between anatomical structures and a procedure utilizing same
US20080021460A1 (en) * 2006-07-20 2008-01-24 Warsaw Orthopedic Inc. Apparatus for insertion between anatomical structures and a procedure utilizing same
US20090227990A1 (en) * 2006-09-07 2009-09-10 Stoklund Ole Intercostal spacer device and method for use in correcting a spinal deformity
US20100030269A1 (en) * 2006-09-07 2010-02-04 Jean Taylor Interspinous spinal prosthesis
US8043378B2 (en) 2006-09-07 2011-10-25 Warsaw Orthopedic, Inc. Intercostal spacer device and method for use in correcting a spinal deformity
US20080065219A1 (en) * 2006-09-08 2008-03-13 Justin Dye Offset radius lordosis
US8506636B2 (en) 2006-09-08 2013-08-13 Theken Spine, Llc Offset radius lordosis
US20080077241A1 (en) * 2006-09-22 2008-03-27 Linh Nguyen Removable rasp/trial member insert, kit and method of use
US20080161920A1 (en) * 2006-10-03 2008-07-03 Warsaw Orthopedic, Inc. Dynamizing Interbody Implant and Methods for Stabilizing Vertebral Members
US8092533B2 (en) 2006-10-03 2012-01-10 Warsaw Orthopedic, Inc. Dynamic devices and methods for stabilizing vertebral members
US20080161919A1 (en) * 2006-10-03 2008-07-03 Warsaw Orthopedic, Inc. Dynamic Devices and Methods for Stabilizing Vertebral Members
US20090125030A1 (en) * 2006-10-18 2009-05-14 Shawn Tebbe Dilator
US9566086B2 (en) 2006-10-18 2017-02-14 VeriFlex, Inc. Dilator
US8845726B2 (en) 2006-10-18 2014-09-30 Vertiflex, Inc. Dilator
US20090264932A1 (en) * 2006-10-19 2009-10-22 Simpirica Spine, Inc. Methods and systems for constraint of multiple spine segments
US8029541B2 (en) 2006-10-19 2011-10-04 Simpirica Spine, Inc. Methods and systems for laterally stabilized constraint of spinous processes
US20080262549A1 (en) * 2006-10-19 2008-10-23 Simpirica Spine, Inc. Methods and systems for deploying spinous process constraints
US20080108993A1 (en) * 2006-10-19 2008-05-08 Simpirica Spine, Inc. Methods and systems for deploying spinous process constraints
WO2008051423A1 (en) 2006-10-19 2008-05-02 The Board Of Trustees Of The Leland Stanford Junior University Methods and systems for constraint of spinous processes with attachment
WO2008051802A2 (en) 2006-10-19 2008-05-02 Simpirica Spine, Inc. Methods and systems for constraint of multiple spine segments
WO2008051801A2 (en) 2006-10-19 2008-05-02 Simpirica Spine, Inc. Structures and methods for constraining spinal processes with single connector
US8454660B2 (en) 2006-10-19 2013-06-04 Simpirica Spine, Inc. Methods and systems for laterally stabilized constraint of spinous processes
US9295499B2 (en) 2006-10-19 2016-03-29 Empirical Spine, Inc. Methods and systems for laterally stabilized constraint of spinous processes
US8162982B2 (en) 2006-10-19 2012-04-24 Simpirica Spine, Inc. Methods and systems for constraint of multiple spine segments
US8187307B2 (en) 2006-10-19 2012-05-29 Simpirica Spine, Inc. Structures and methods for constraining spinal processes with single connector
US20080177264A1 (en) * 2006-10-19 2008-07-24 Simpirica Spine, Inc. Methods and systems for laterally stabilized constraint of spinous processes
US8790372B2 (en) 2006-10-19 2014-07-29 Simpirica Spine, Inc. Methods and systems for constraint of multiple spine segments
US20080177391A1 (en) * 2006-10-24 2008-07-24 St. Francis Medical Technologies, Inc. Systems and Methods for In Situ Assembly of an Interspinous Process Distraction Implant
US8097019B2 (en) 2006-10-24 2012-01-17 Kyphon Sarl Systems and methods for in situ assembly of an interspinous process distraction implant
US8641762B2 (en) 2006-10-24 2014-02-04 Warsaw Orthopedic, Inc. Systems and methods for in situ assembly of an interspinous process distraction implant
US20080177333A1 (en) * 2006-10-24 2008-07-24 Warsaw Orthopedic, Inc. Adjustable jacking implant
US20080177298A1 (en) * 2006-10-24 2008-07-24 St. Francis Medical Technologies, Inc. Tensioner Tool and Method for Implanting an Interspinous Process Implant Including a Binder
US8118839B2 (en) 2006-11-08 2012-02-21 Kyphon Sarl Interspinous implant
US20100070038A1 (en) * 2006-11-08 2010-03-18 Jean Taylor Interspinous implant
US20100152779A1 (en) * 2006-11-15 2010-06-17 Warsaw Orthopedic, Inc. Inter-transverse process spacer device and method for use in correcting a spinal deformity
US20080114456A1 (en) * 2006-11-15 2008-05-15 Warsaw Orthopedic, Inc. Spinal implant system
US20080114455A1 (en) * 2006-11-15 2008-05-15 Warsaw Orthopedic, Inc. Rotating Interspinous Process Devices and Methods of Use
US7879104B2 (en) 2006-11-15 2011-02-01 Warsaw Orthopedic, Inc. Spinal implant system
US20080114357A1 (en) * 2006-11-15 2008-05-15 Warsaw Orthopedic, Inc. Inter-transverse process spacer device and method for use in correcting a spinal deformity
US7955392B2 (en) 2006-12-14 2011-06-07 Warsaw Orthopedic, Inc. Interspinous process devices and methods
US8075596B2 (en) 2007-01-12 2011-12-13 Warsaw Orthopedic, Inc. Spinal prosthesis systems
US20080172090A1 (en) * 2007-01-12 2008-07-17 Warsaw Orthopedic, Inc. Spinal Prosthesis Systems
US9451989B2 (en) 2007-01-18 2016-09-27 Roger P Jackson Dynamic stabilization members with elastic and inelastic sections
US8475498B2 (en) 2007-01-18 2013-07-02 Roger P. Jackson Dynamic stabilization connecting member with cord connection
US7901437B2 (en) 2007-01-26 2011-03-08 Jackson Roger P Dynamic stabilization member with molded connection
US9101404B2 (en) 2007-01-26 2015-08-11 Roger P. Jackson Dynamic stabilization connecting member with molded connection
US20080234824A1 (en) * 2007-02-06 2008-09-25 Youssef Jim A Interspinous dynamic stabilization implant and method of implanting
US8034081B2 (en) * 2007-02-06 2011-10-11 CollabComl, LLC Interspinous dynamic stabilization implant and method of implanting