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Embolic protection device

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Publication number
US20040039411A1
US20040039411A1 US10410606 US41060603A US20040039411A1 US 20040039411 A1 US20040039411 A1 US 20040039411A1 US 10410606 US10410606 US 10410606 US 41060603 A US41060603 A US 41060603A US 20040039411 A1 US20040039411 A1 US 20040039411A1
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Prior art keywords
filter
element
end
distal
device
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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US10410606
Inventor
Paul Gilson
Eamon Brady
Padraig Maher
David Vale
Charles Taylor
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Paul Gilson
Eamon Brady
Padraig Maher
David Vale
Charles Taylor
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2/013Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stending
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • A61B2017/22065Functions of balloons
    • A61B2017/22067Blocking; Occlusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2002/011Instruments for their placement or removal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2/013Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stending
    • A61F2002/015Stop means therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2002/016Filters implantable into blood vessels made from wire-like elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/01Filters implantable into blood vessels
    • A61F2002/018Filters implantable into blood vessels made from tubes or sheets of material, e.g. by etching or laser-cutting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004Rounded shapes, e.g. with rounded corners
    • A61F2230/0006Rounded shapes, e.g. with rounded corners circular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0067Three-dimensional shapes conical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0093Umbrella-shaped, e.g. mushroom-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0097Harpoon-shaped

Abstract

An embolic protection device has a collapsible filter element (105) mounted on a carrier such as a guidewire (101). The filter element (105) collapses into the outer end of a catheter (118) for deployment and retrieval through a vascular system of a patient. The filter element (105) has a collapsible filter body with a proximal inlet end and a distal outlet end. The proximal inlet end has inlet openings sized to allow blood and embolic material enter the filter body. The outlet end has outlet openings which allow through passage of blood but retain embolic material within the filter body. After use, the catheter (118) is movable along the guidewire (101) to engage the proximal end of the filter element and close the inlet openings before sliding over the filter element from the proximal end to the distal end to progressively collapse the filter body on the guidewire (101) for retrieval. The filter element (105) may conveniently be mounted on a tubular sleeve (104) which is slidable and rotatable on the guidewire (101) between spaced-apart stops (106, 120) on the guidewire (101) which allows some manipulation of the guidewire independently of the filter when the filter is in use.

Description

  • [0001]
    The invention relates to an embolic protection device
  • [0002]
    The term “STROKE” is used to describe a medical event whereby blood supply to the brain or specific areas of the brain is restricted or blocked to the extent that the supply is inadequate to provide the required flow of oxygenated blood to maintain function. The brain will be impaired either temporarily or permanently, with the patient experiencing a loss of function such as sight, speech or control of limbs There are two distinct types of stroke, haemorrhagic and embolic. This invention addresses embolic stroke.
  • [0003]
    Medical literature describes carotid artery disease as a significant source of embolic material. Typically, an atherosclerotic plaque builds up in the carotid arteries, The nature of the plaque varies considerably, but in a significant number of cases pieces of the plaque can break away and flow distally and block bloodflow to specific areas of the brain and cause neurological impairment. Treatment of the disease is classically by way of surgical carotid endarterectomy whereby, the carotid artery is cut and the plaque is physically removed from the vessel. The procedure has broad acceptance with neurological complication rates quoted as being low, somewhere in the order of 6% although claims vary widely on this.
  • [0004]
    Not all patients are candidates for surgery. A number of reasons may exist such that the patients could not tolerate surgical intervention. In these cases and an increasing number of candidates that are surgical candidates are being treated using transcatheter techniques. In this case, the evolving approach uses devices inserted in the femoral artery and manipulated to the site of the stenosis A balloon angioplasty catheter is inflated to open the artery and an intravascular stent is sometimes deployed at the site of the stenosis. The action of these devices as with surgery can dislodge embolic material which will flow with the arterial blood and if large enough, eventually block a blood vessel and cause a stroke.
  • [0005]
    It Is known to permanently implant a filter in human vasculature to catch embolic material. It is also known to use a removable filter for this purpose. Such removable filters typically comprise umbrella type filters comprising a filter membrane supported on a collapsible frame on a guidewire for movement of the filter membrane between a collapsed position against the guidewire and a laterally extending position occluding a vessel. Examples of such filters are shown in U.S. Pat. No. 4,723,549, U.S. Pat. No. 5,053,008, U.S. Pat. No. 5,108,419 and WO 98/33443. Various deployment and/or collapsing arrangements are provided for the umbrella filter. However, as the filter collapses, the captured embolic material tends to be squeezed outwardly towards an open end of the filter and pieces of embolic material may escape from the filter with potentially catastrophic results. More usually, the filter umbrella is collapsed against the guidewire before removal through a catheter or the like. Again, as the filter membrane is collapsed, it will tend to squeeze out the embolic material. Further, the umbrella filter is generally fixed to the guidewire and any inadvertent movement of the guidewire during an Interventional procedure can dislodge the filter.
  • [0006]
    The present invention is directed towards overcoming these problems.
  • [0007]
    There is a need for an embolic protection device which will overcome this problem.
  • [0008]
    Statements of Invention
  • [0009]
    According to the invention, there is provided an embolic protection device comprising:
  • [0010]
    a collapsible filter element mounted on a filter carrier for delivery through a vascular system of a patient,
  • [0011]
    the filter element being movable between a collapsed stored position against the filter carrier for movement through the vascular system, and an expanded position for occluding a blood vessel such that blood passing through the blood vessel is delivered through the filter element,
  • [0012]
    the filter element comprising a collapsible filter body having an inlet end and an outlet end,
  • [0013]
    the inlet end of the filter body having one or more inlet openings sized to allow blood and embolic material enter the filter body,
  • [0014]
    the outlet end of the filter body having a plurality of outlet openings sized to allow through passage of blood but to retain undesired embolic material within the filter body,
  • [0015]
    means for closing the inlet openings at he inlet end of the filter body, and
  • [0016]
    means for collapsing the filter body on the support.
  • [0017]
    Advantageously, the inlet openings in the filter are closed before the filter is collapsed ensuring retention of all embolic material within the filter element.
  • [0018]
    In a particularly preferred embodiment of the invention, the means for closing the inlet comprises:
  • [0019]
    a tubular filter retrieval device having an open distal end for reception of the filter element,
  • [0020]
    said distal end being engagable with a proximal inlet end of the filter body to close the inlet openings and being slidable over the filter body from the inlet end to the outlet end to progressively collapse the filter body on the filter carrier and receive the filter body within the retrieval device.
  • [0021]
    Conveniently, the retrieval device which may be a catheter or pod or the like which engages and collapses the filter element firstly closing the inlet openings to prevent any escape of embolic material and then collapsing the remainder of the filter, being slid from the proximal end over the filter to the distal end of the filter.
  • [0022]
    In a particularly preferred embodiment, the collapsible filter element is slidably mounted on the filter carrier between the a pair of spaced-apart stops on the filter carrier for axial movement of the filter element along the filter carrier between the stops.
  • [0023]
    Advantageously, the filter carrier which may for example be a guidewire can be moved independently of the filter element and thus accidental movement of the guidewire is accommodated without unintentionally moving the filter, for example, during exchange of medical devices.
  • [0024]
    In a further embodiment, the filter element is rotatably mounted on the filter carrier.
  • [0025]
    In a preferred embodiment, a sleeve is slidably mounted on the filter carrier between the stops, the length of the sleeve being less than the distance between the stops, the filter element being mounted on the sleeve.
  • [0026]
    In a particularly preferred embodiment, the filter element comprises:
  • [0027]
    a collapsible filter net mounted on the filter carrier,
  • [0028]
    the filter net being movable between a collapsed stored position against the filter carrier and an expanded position extending outwardly of the filter carrier for deployment across a blood vessel.
  • [0029]
    Preferably, the tubular filter retrieval device comprises a catheter slidable along the filter carrier, an open distal end of the catheter forming a housing for reception of the filter element.
  • [0030]
    In another embodiment, a proximal inlet end of the filter body is fixed to the filter carrier and a distal end of the filter body is slidably mounted on the filter carrier, although this arrangement may be reversed.
  • [0031]
    In a further embodiment, the distal end of the filter body is attached to a collar which is slidable along the filter carrier.
  • [0032]
    In a preferred embodiment, a filter support frame is mounted on the filter carrier., the support frame being movable between a collapsed position along the filter carrier and an extended outwardly projecting position to support the filter body in the expanded position.
  • [0033]
    In another embodiment, the filter support frame is fixed on the filter carrier at a proximal end of the filter body.
  • [0034]
    Preferably, the filter support frame slidably engages the filter carrier at a distal end of the filter body ideally, the filter support frame Is biased into a normally extended position.
  • [0035]
    In a further embodiment, a circumferential groove is provided in the filter body intermediate the ends of the filter body.
  • [0036]
    In another embodiment, a guide olive is provided on the filter carrier distally of the filter body, the guide olive having a cylindrical body with a tapered distal end, the cylindrical body being engagable within a distal end of a deployment catheter, said tapered distal end projecting outwardly of the deployment catheter to provide a smooth transition between the catheter and the filter carrier.
  • [0037]
    In a further embodiment, the net is gathered into the filter carrier at each end of the net.
  • [0038]
    In another embodiment of the invention, there is provided an embolic protection device comprising a filter element for placing in a desired position, the filter element providing a pathway for blood and having means for capturing, retaining and removing undesired embolic material.
  • [0039]
    In one embodiment of the invention, the pathway has means for constricting flow to capture undesired embolic material.
  • [0040]
    In another embodiment of the invention, the filter has a proximal end and a distal end, openings in the proximal end being larger than openings In the distal end, the proximal end openings being sized to allow the flow of blood and embolic material to enter the filter element and the distal end openings being sized to allow the flow of blood while capturing undesired emboli within the filter element.
  • [0041]
    In a further embodiment of the invention, the filter element includes storage means to store captured undesired embolic material in the filter element. Preferably, the storage means comprises additional storage pathways Within the filter element. Preferably, the filter element defines a three dimensional matrix.
  • [0042]
    In another embodiment of the invention, the fitter element is of a polymeric porous structure. In a further embodiment of the invention, the matrix comprises a porous structure dimensioned to entrap embolic material which typically ranges in size from about 100 microns to 3500 microns. In a still further embodiment of the invention, the filter element is compressible and/or foldable for loading into a delivery device to deliver the filter element to a desired location In the compressed or folded state.
  • [0043]
    In one embodiment of the invention the filter element has material removed from its structure to aid compressibility.
  • [0044]
    In another embodiment of the invention, the filter element has material removed from its structure to provide specific sizing in relation to the size of embolic material to be trapped.
  • [0045]
    In a further embodiment of the invention, the filter element has pathways through the filter body that are inter-linked such that the flow rate through the filter may be tailored.
  • [0046]
    In another embodiment of the invention, the filter element has a distal end which is tapered such that there is a smooth transition in lateral stiffness to improve the manoeuvrability of the filter element in the vascular system.
  • [0047]
    In a further embodiment of the invention, the filter element has a soft distal portion to aid in atraumatic transport through the vascular system. Preferably, the filter element has circumferential grooves to reduce the lateral flexibility of the fitter element.
  • [0048]
    In one embodiment of the invention, the filter element has a tapered proximal end to facilitate retrieval by a removal catheter.
  • [0049]
    In another embodiment of the invention, the filter element has inlet holes that close on pulling back into a retrieval catheter to ensure retention of any collected emboli.
  • [0050]
    In a further embodiment of the invention, the filler element has outlet openings sized to capture embolic material of a size large enough to impair the function of the organ receiving the blood downstream of the filter body element. Preferably, the filter element is sized to capture embolic material of a size greater than 100 microns. Most preferably, the filter element is sized to capture embolic material of a size greater than 200 microns. Most preferably, the filter element is sized to capture embolic material of a size greater than 500 microns.
  • [0051]
    In one embodiment of the invention, the filter element is sized for complete coverage of a vessel cross-section that allows passage of blood and blood components.
  • [0052]
    In a still further embodiment of the invention, there is provided a device having means for placing over a medical guidewire.
  • [0053]
    In another embodiment of the invention, there is provided a device which may be placed under a balloon or stent delivery catheter.
  • [0054]
    In a further embodiment of the invention, there is provided a device having means for insertion through, femoral, brachial, radial, subclavian or other arterial puncture by means of a transcatheter approach.
  • [0055]
    In one embodiment of the invention, there is provided a device for protection of neurological function which is inserted for the duration of a surgical intervention at or near the site of surgical opening.
  • [0056]
    It is envisaged that two devices could be used bilaterally in left and right carotid arteries allowing sufficient cerebral blood flow to maintain neurological function during procedures with a high risk of generating clot such as electrophysiological treatment of coronary arrhythmias.
  • [0057]
    In a further embodiment of the invention, there is provided a device including a delivery catheter in which an external sheath is engagable with the filter element or filter carrier to provide push during delivery and is removable to allow maximum space in the vascular cross-section during an interventional procedure.
  • [0058]
    In one embodiment of the invention, the external sheath is joined to the filter element or filter carrier by a joining means. The joining means may be a removable shrink tube or a removable clip. Preferably the joining means is a compression connector such as a Tuohy Borst adapter.
  • [0059]
    In another embodiment of the invention, the delivery catheter has a central lumen for at least part of it's length to allow it to track over a steerable guidewire.
  • [0060]
    In a further embodiment of the invention, the external sheath is sufficiently long to extend to the outside of the vasculature and is movable proximally to release the filter element from the catheter.
  • [0061]
    In one embodiment of the invention, the delivery catheter has an external covering which extends beyond the push element to define a filter retention sleeve.
  • [0062]
    In another embodiment of the invention, the delivery catheter has a spring component with a localised stepwise increasing pitch to alter stiffness characteristics to suit the target vasculature.
  • [0063]
    In a further embodiment of the invention, the delivery catheter has a spring component with a localised gradually increasing pitch to alter stiffness characteristics to suit the target vasculature.
  • [0064]
    In one embodiment of the invention, the filter element is mounted on a collapsible support structure which is movable between a collapsed position for deployment and an extended in-use position, means being provided for retaining the support structure in the collapsed position. Preferably, the support structure comprises support arms. Preferably, the support arms are formed from a shape memory or elastic memory material. Most preferably, the support arms are formed from Nitinol.
  • [0065]
    In one embodiment of the invention, the support arms are configured to open co-axially with the filter carrier such that they may be restrained for removal by pulling the filter element proximally into an appropriately dimensioned sheath.
  • [0066]
    In another embodiment of the invention, the filter element has an associated support structure with a pre-shaped spiral arrangement such that it provides radial support to the filter element.
  • [0067]
    In a further embodiment of the invention, the filter support structure is adapted to fold into the collapsed position when pulled into a retrieval catheter.
  • [0068]
    In one embodiment of the invention, the filter element comprises a flexible shaped polymeric component.
  • [0069]
    In another embodiment of the invention, the shaped polymeric component is constructed such that fluid flow through the component assists in opening the component from the collapsed position.
  • [0070]
    In a further embodiment of the invention, the shaped polymeric component is flexible and opens to make circumferential contact with the vessel wall by way of using the pressure drop across the exit filter face.
  • [0071]
    In a further embodiment of the invention the fitter element is mounted on a guidewire such that the guidewire has freedom to rotate and/or move axially independently of the filter. More preferably the wire has complete freedom to rotate independently of the filter and has limited axial movement. The limit of axial movement is determined by stops mounted on or connected to the wire. Ideally the wire can move 100 mm in the axial direction independent of the filter. More ideally the wire can move less than 50 mm independently of the filter. This embodiment facilitates the maintenance of filter position during the exchange of catheters and permits the steering of the wire independent of the filter.
  • [0072]
    In a further embodiment of this invention the filter element is bonded to the filter mount at its proximal end and its distal end is free to move relative to the filter mount and proximal bond so as to aid the collapse of the filter for deployment.
  • [0073]
    In a further embodiment of the invention the filter element is tapered over part or all of its length such that it is accurately sized to the vessel over some portion of its length.
  • [0074]
    In a further embodiment of the invention the shaped polymeric component contains one or more circumferential grooves along its body to maintain the circular shape of the filter element In an under sized artery.
  • [0075]
    In one embodiment of the invention, the filter element is directly bonded onto a steerable medical guide wire incorporating a slidable sheath that is movable to deploy the filter.
  • [0076]
    In another embodiment of the invention, there is provided a device incorporating a medical guidewire with a flexible segment of wire distal to the filter so as to provide steerability of the wire particularly prior to it being deployed.
  • [0077]
    In a further embodiment of the invention, there is provided a device incorporating a medical guide wire with a soft distal segment so as to provide a tip section that will be atraumatic.
  • [0078]
    In a still further embodiment of the invention, there is provided a device with a porous coating on a distal end of the filter element only with a means for opening and closing the filter by slidable motion.
  • [0079]
    In one embodiment of the invention, the filter element incorporates proximal tapering such that it may be pulled proximally into a sheath for removal in order that such pulling action will effectively reduce the diameter of the filter and assist retrieval.
  • [0080]
    In another embodiment of the invention, the filter element has a porous structure that can be deployed and closed by way of a slidable motion, the closure thereof caused by way of snap-fit to a protruding rim that allows the support elements be pulled proximally, thus closing the structure with the filter membrane attached.
  • [0081]
    In a further embodiment of the invention, there is provided a device having a filter element which permits the incorporation of a medical guide wire in the outer wall of the filter element to facilitate the incorporation of large inlet holes on the proximal inlet end of the filter element.
  • [0082]
    In one embodiment of the invention, the filter element comprises a mesh work structure with large proximal inlet holes and small distal outlet holes wherein the mesh structure is collapsible into a small diameter delivery catheter and is expandable upon deployment to a shape which is remembered by the mesh structure either through shape memory characteristics or elastic memory characteristics.
  • [0083]
    In another embodiment of the invention, the filter element comprises a mesh work structure wherein the expansion of the filter element within the vessel causes blood flowing through the vessel to flow through the filter element due to the filter element engaging with the wall of the vessel to conform to the shape of the vessel bore.
  • [0084]
    In another embodiment, the filter element comprises a braided fibrous mesh work. Preferably, distal outlet openings are defined by an area enclosed by a series of crossing interwoven fibres. Larger proximal inlet holes are provided by the convergence of the fibres of the braid into a few bundles which are mounted to the filter carrier. Preferably, the fibrous meshwork material is an elastic or shape memory material such that it can be collapsed into a delivery catheter and recover its enlarged shape upon deployment. The fibres of the meshwork are bonded at the points where they cross one another. The fibres may be made from either a polymer or metal or a composite material.
  • [0085]
    In a further embodiment, the distal end of the filter element has the facility to move in the axial direction relative to the proximal end of the filter element so as to take up the exact shape of the blood vessel.
  • [0086]
    In a further embodiment, the device has a porous coating on a distal end of the filter element only with means for opening and closing the filter element by slidable motion. Preferably, the filter element comprises a collapsible wire frame having a plurality of wires, outer ends of the wires being hingedly mounted on the filter carrier, the wires being hinged intermediate their ends, at one end the wires being fixed on the filter carrier and at the other end the wires being mounted on a collar which is slidable along the filter carrier, a porous filter mesh being mounted on the wire frame. An actuating sleeve is slidable over the filter carrier to push the collar towards the fixed end of the filter element, and a collapsing device is engagable with the collar to pull back the collar away from the fixed end of the filter element to collapse the wire frame against the filter carrier for retrieval of the filter element.
  • [0087]
    In a still further embodiment of the invention, there is provided a filter retrieval system for use with the device comprising a longitudinal catheter with a radially deformable or elastic up to assist the pull back of the filter Into the tip.
  • [0088]
    In another embodiment of the invention, there is provided a system incorporating a filter, a delivery catheter and a retrieval catheter for temporary filtration of the vascular system during an Interventional procedure.
  • [0089]
    In another aspect the invention provides an embolic protection device comprising:
  • [0090]
    a collapsible filter element mounted on a filter carrier for delivery through a vascular system of a patient.
  • [0091]
    the filler element being movable between a collapsed stored position against the filter carrier for movement through the vascular system, and an expanded position for occluding a blood vessel such that blood passing through the blood vessel is delivered through the filter element, a pair of spaced-apart stops on the filter carrier, the collapsible filter element being slidably mounted on the filter carrier for axial movement along the filter carrier between the stops, and means for collapsing the filter element on the filter carrier.
  • BRIEF DESCRIPTION OF DRAWINGS
  • [0092]
    The invention will be more clearly understood from the following description thereof given by way of example only with reference to the accompanying drawings in which:
  • [0093]
    [0093]FIG. 1 is a side view of an embolic protection device according to the invention, in use;
  • [0094]
    [0094]FIG. 2 is a side view of the device of FIG. 1 in a pre-loaded position for insertion;
  • [0095]
    [0095]FIG. 3A is a side view illustrating one method of fixing the device to catheter;
  • [0096]
    [0096]FIG. 3B is a side view of an embolic protection device incorporating the fixing of FIG. 3A;
  • [0097]
    [0097]FIG. 4 is a side view illustrating another method of fixing;
  • [0098]
    [0098]FIG. 5 is an end view of a split collar used in the fixing of FIG. 4;
  • [0099]
    [0099]FIG. 6 is a side view illustrating a further method of fixing;
  • [0100]
    [0100]FIG. 7 is an end view of a jubilee clip used in the fixing of FIG. 6;
  • [0101]
    [0101]Fig. 8 is a side view of one filter element used in the device of the invention;
  • [0102]
    [0102]FIG. 9 is a side view of another filter element;
  • [0103]
    [0103]FIG. 10 is a side view of the filter element of FIG. 8 being removed;
  • [0104]
    [0104]FIG. 11 is an isometric view of another filer element in an in-use placed configuration,
  • [0105]
    [0105]FIG. 12 is a side view of the filter element of FIG. 11 in a retracted position for insertion and withdrawal;
  • [0106]
    FIGS. 13 to 15 are side views of another filter element in different positions;
  • [0107]
    [0107]FIGS. 16 and 17 are side views of part of a further filter element with a snap fit retrieval arrangement;
  • [0108]
    [0108]FIG. 18 is a perspective, partially cross-sectional view of another embolic protection device shown mounted in a vessel;
  • [0109]
    [0109]FIGS. 19a to 19 c are perspective views illustrating the formation of a collapsible fitter support for use in the device of FIG. 18;
  • [0110]
    FIGS. 20 to 22 are perspective views of other filter elements;
  • [0111]
    [0111]FIG. 23 is an elevational view of another filter element;
  • [0112]
    [0112]FIG. 24 is a sectional view taken along the line XXIV-XXIV of FIG. 23;
  • [0113]
    [0113]FIG. 25 is a sectional view taken along the line XXV-XXV of FIG. 23;
  • [0114]
    [0114]FIG. 26 is an enlarged detail view of portion of the filter;
  • [0115]
    [0115]FIG. 27 is an expanded view of the filter element of FIG. 23;
  • [0116]
    [0116]FIG. 28 is a side view illustrating one method in which the substrate tubing that the filter element is attached to can run over the primary crossing guidewire;
  • [0117]
    [0117]FIG. 29 is a side view illustrating the position In which the ‘olive’ component will sit in order to provide a smooth transition between the primary crossing guidewire and the loading pod; FIG. 30 is a perspective view of the filter element in its most distal position; FIG. 31 is a perspective view of the filter element in its most proximal position; FIG. 32 Is a perspective view of the filter element when the distal end of the filter is not bonded to the substrate tubing; FRg. 33 is a side view of a concertina shaped filter; A being when the filter is deployed and B when the filter Is In its loaded shape;
  • [0118]
    [0118]FIG. 34 is a perspective view of the floating distal tip design with a spring element incorporated distal to the floating tip;
  • [0119]
    [0119]FIG. 35 is a side view of another floating distal tip design with a spring incorporated into the distal tip;
  • [0120]
    [0120]FIG. 36 is a side view of the floating distal tip design with the shape memory alloy extending from the proximal end to the distal end;
  • [0121]
    [0121]FIG. 37 is a perspective view of the mesh design incorporating a floating distal tip;
  • [0122]
    [0122]FIG. 38 illustrates perspective views of filter geometries;
  • [0123]
    [0123]FIG. 39 shows a fibrous mesh filter design with fibres woven at the distal end and converging into a number of bundles at the proximal end;
  • [0124]
    [0124]FIG. 40 is partially sectioned elevational view an embolic protection device according to the invention;
  • [0125]
    [0125]FIG. 41 is a schematic sectional elevational view of the embolic protection device of FIG. 40; and
  • [0126]
    [0126]FIG. 42 is a detail sectional view of portion of the device of FIG. 40.
  • DETAILED DESCRIPTION
  • [0127]
    Referring to the drawings there are illustrated various embolic protection devices according to the invention. The devices, in general, comprise a filter element for temporary placing in a desired position during a surgical or interventional procedure, typically using a guidewire and catheter. The filter element provides a pathway for blood and has means for capturing and retaining undesired embolic material released during the surgical procedure. The filter element containing the retained embolic material is removed when the interventional procedure is completed. In this way the patient is protected against the risk of stroke or other complications caused by the release of undesired embolic material during the procedure.
  • [0128]
    In one embodiment of the device it will be used in an over the wire transcatheter configuration. The clinician will cross the lesion with a steerable guidewire. The cerebral protection device will then be threaded over the guidewire and will be placed distal to the site of the lesion being treated by means of actuation, or other means, the filter is deployed into the vessel and will capture emboli that are generated or dislodged during balloon inflation and stent placement. The device consists of a filter attached to a shaft that can run over the primary crossing guidewire.
  • [0129]
    Referring initially to FIGS. 1 and 2 In this case the filter element consists of a compressible porous structure polymeric foam filter element 1 overmoulded onto or joined to a polymeric or metallic tube or spring or other hollow support element 2. The foam filter element 1 is compressed into a housing or pod 3 at a distal end of a catheter 6 to advance it to the required location. Once In situ the housing 3 is withdrawn or the filter element 1 is advanced. This action allows the compressed filter element 1 to expand to the required size and occlude a blood vessel 4 except for the path or paths provided through the filter element 1. The filter element 1 is designed to provide a pathway or multiple pathways through for blood cells and other blood constituents but to capture emboli of a size greater than the filter pore size. Blood flow rate is maintained by forming the filter element such that a local pressure drop across the filter is minimised. The filter element 1 has a proximal inlet end 7 and a distal outlet end B. The inlet end 7 has a plurality of inlet openings sized to allow blood and embolic material enter the filter element. The outlet end 8 has a plurality of outlet openings sized to allow through passage of blood but to retain undesired embolic material within the body of the filter element 1.
  • [0130]
    The filter element 1 in this case is of a porous structure or polymeric foam which has a open cell structure with a typical density less than 400 kg per cubic meter. Preferably the density will be less than 100 kg per cubic meter and ideally will be less than 50 kg per cubic meter. The filter properties may be achieved through appropriately sizing the pores of the foam body or additionally by removing material to create appropriately sized pathways for blood to flow through and means of capturing larger sized particles. A number of configurations for this will be described that can tailor both the sizing and flow rate characteristics of the filter element 1 either independently or simultaneously. The actuation and deployment of the filter element 1 are achieved by providing relative motion between the filter element 1 and the covering housing 3.
  • [0131]
    It is not desirable that the catheter moves relative to the support element 2 during manipulation. Motion may be prevented by fixing the inner support element 2 to the catheter 6 in a number of different ways. In the embodiment described this is achieved by way of having a catheter 6 covering the support element 2 and filter element 1 to which it is fixed. As illustrated in FIGS. 5A and 3B the fixing may be achieved by means of a shrink wrap tube 5 that is shrunk to capture both the covering catheter 6 and the inner support element 2. Once the filter element 1 is in the desired position, the shrink-wrap joint is broken using the peel-away tab 7 to allow the outer catheter 6 to be removed proximally and leave the support element 2 and filter element 1 in place.
  • [0132]
    A number of other workable arrangements could be used to join the support element 2 and catheter 6. A split collar arrangement 10 (FIGS. 4 & 5) could be used that was removable by means of unlocking a screw or a number of screws or an arrangement such as a jubilee clip 11 (FIGS. 6 & 7) which could be loosened to free the bond between the components.
  • [0133]
    Another method that could be used to temporarily fix the inner support element 2 to the outer sheath or catheter 6 is a Hemostasis High Pressure Touhy Borst Y adapter. This commercially available adapter is needed to enable the physician to flush the sheath before being inserted into the artery. The outer sheath or catheter may be permanently attached to this adapter. The inner tubular support element 2 runs through the Touhy Borst section of the adapter and thus through the centre of the sheath. Tightening the Touhy Borst section releases this grip, thus allowing the inner tubular support element 2 and the outer sheath to move relative to each other once again.
  • [0134]
    The design of the filter element 1 is shown in a typical embodiment in Fig. B, where a foam substrate fitter body has material removed to create a series of channels or pathways 20 for the blood to flow through but which would cause a restriction for embolic material to prevent it going through the filter. The pathways 20 may be machined using a variety of methods such as laser cutting with excimer, YAG, CO2, or other laser type, freezing and machining or lost wax machining. A number of arrangements are possible with the sizing reflective of the requirements. In the configuration shown, the inlet holes are preferably 0.5 mm or greater in size to capture large emboli while the outlet holes are less than 300 microns. These can be easily varied as required to filter differing sized particles from a variety of fluid media in a variety of vessel sizes.
  • [0135]
    The filter media can be bonded to the tubing substrate by way of a variety of available technologies such as mechanical, solvent or adhesive bonding and overmoulding in an arrangement such that the substrate is placed in the mould and the polymer material is then shot into the mould and forms a bond at the interface between the substrate and the polymer element. Additionally, the foam or porous element could be extruded onto or bonded to a substrate.
  • [0136]
    It will be noted that the filter element 1 has a rounded distal end 21 to facilitate insertion and the proximal end 22 is tapered to facilitate withdrawal. Alternatively, as illustrated In FIG. 9 the distal end 23 may be tapered.
  • [0137]
    Referring particularly to FIG. 10 at the end of the interventional procedure, the device can be withdrawn by means of advancing a large bore catheter 25 to the proximal end 22 of the filter 1 and pulling the filter 1 Into the catheter 25. The filter 1 will compress and seal the proximal filter inlet openings after the initial taper is drawn into the catheter 25 before collapsing the rest of the filter body. Once the filter 1 has been withdrawn fully into the catheter 25 it can then be readily removed from the patient. The filter 1 will contain the captured emboli.
  • [0138]
    In another embodiment of the invention as illustrated In FIGS. 11 to 15, an arrangement of spokes 30 covered with a membrane or porous fabric or mesh 31 can be folded down into a delivery sheath or pod for subsequent deployment in the target vessel. The design consists of a substrate shaft 33 onto which are radially or circumferentially bonded a series of pre-shaped wires 30. The wires 30 are joined on the proximal end into a movable collar or tube 32 mounted on the substrate shaft 33 and at the distal end into a fixed tube 34. The tube 32 can move proximally and distally to the extent that it will open and close the assembly in a manner similar to an umbrella and thereby occlude the vessel. The spokes 30 may be fabricated in a range of metallic, polymeric and composite materials. The frame is covered with a porous material 31, whose pore size is selected to allow the media through, effectively creating a screen filter. The covering fabric 31 could be bonded to the frame 30 by means of casting a material such as a polyurethane or PET onto the pre-formed shape. The film may then be lazed or made porous by other means such as mechanical or heat punching or by chemical etching Additionally, incorporating a soluble particle in the polymer matrix, subsequent removal of the particle would render the polymer porous. Control of porosity is achieved by tailoring the ratio and distribution of the particulate within the polymer matrix.
  • [0139]
    When the assembly is configured longitudinally a sheath or pod may be slid over it to cover it. As with the previous embodiment, the loaded catheter is positioned in the required location by threading it over the guidewire. Once the desired location has been reached, the sheath may be moved back and allow the assembly be exposed in the vessel. A sleeve 35 can then be moved forward to open or deploy the assembly. The relative sizing and choice of materials operates such that the sleeve 35 will not slide on the inner tubing unless an external force is applied to move it. When deployed, the device will remain open and catch whatever embolic material is moving towards the brain. At the end of the procedure, a pre-shaped component advanced over the inner tube will dock with the movable tube 32 and allow it to be slid towards the proximal end of the device with the result that the structure is closed A larger sheath can then separately be advanced to the site of the filter and the filter may be pulled or manipulated proximally into it. When withdrawn into the sheath or catheter, the device may then be removed either over the guidewire or with it.
  • [0140]
    Referring to FIGS. 16 and 17 there is illustrated another embolic protection device. In this case the filter element has a design based on a shaped thin film component bonded onto the tubing substrate. A wide number of shapes could be made to work in the application. An element which through it's preshaped form will open into a framework 40 when the restraining force is removed is attached to a tubing substrate 41. The frame element 40 can be manufactured from a range of metallic or polymeric components such as a shape memory alloy like Nitinol or a shape memory polymer or a shaped stainless steel or metal with similar properties that will recover from deformation sufficiently to cause the film component to open. Otherwise a mechanical movement or actuation can cause the device to open. The shaped film component is attached over the frame 40. The film component can be formed by a number of known commercial technologies. These include blow-moulding, dip casting, solution casting, spin casting and film welding as well as adhesive joining. The object is to produce a formed shape that can be opened in the vessel to a size and shape to occlude it. Filtration is achieved by creating a pattern or series of openings in the proximal and distal ends of the element that allows emboli and blood to enter the device but having a range of smaller openings in the distal end to allow the blood to pass through to the distal vasculature while retaining the emboli.
  • [0141]
    While being delivered to the required site, the filter element is covered or restrained by a sheath. By withdrawing the sheath or advancing the filter device, the filter is uncovered and opens to occlude the vessel. During the procedure, the filter acts to capture all embolic material that attempts to flow distally. At the end of the procedure, a sheath is advanced to the proximal end of the device and the filter is pulled proximally into it with the retained emboli captured in this design configuration, the emboli can easily be removed for analysis afterwards.
  • [0142]
    The invention above is described as it relates to a device that can be used over a medical guidewire. The opportunity exists to configure the invention in a manner that it could in itself be used as the primary crossing device. All of the filter designs described above could be mounted onto either the over the wire or the primary crossing device as described hereunder. For a primary crossing device the filter would be bonded to a solid substrate. Some benefits would accrue in that the inner diameter onto which the filter could be wrapped down would be smaller because it would not need to move over another instrument. FIG. 18 illustrates the differences involved. The filter element 1 is mounted on the substrate shaft 33. A collapsible filter support element 50 is mounted on the substrate shaft 33 at a proximal end of the filter 1. The support element 50 has a number of foldable arms 51 which collapse against the shaft 33 for deployment and upon release extend outwardly to expand the filter 1 in the vessel.
  • [0143]
    Referring to FIGS. 20 to 22 there is shown alternative constructions of filter element comprising a compressible filter 1 shown in an expanded position with a large inlet opening 60 and smaller outlet openings 61. A collapsible wire support 62 is provided at a proximal end of the filter 1. The wire support 62 is collapsible with the filter 1 within a housing or pod for deployment and upon release expands to support the filter 1 in the vessel 4.
  • [0144]
    An alternative filter arrangement is shown in FIGS. 23 to 27. In this case, the filter comprises a Nitinol mesh which is expandable from a collapsed position shown in FIG. 23 for deployment to an expanded in use position shown in FIG. 27 to provide a filter body 65 with proximal inlet 66 and distal outlets 67.
  • [0145]
    For a primary crossing device, the distal end of the device will be flexible and atraumatic. This can be achieved by a number of means such as fabricating a spring or polymeric element to be flexible enough to deflect when it comes into contact with the walls of the vessel. The tip section would be mounted distally to the filter element. An intermediate section of the device will house the filter 1 which would be covered prior to deployment. A sheath could be fully the length of the device or attached by an actuator to a shorter sheath that covers the filter only. The proximal section of the device will provide a platform for the balloon dilatation and stent devices. The provision of a platform may be achieved as shown by removing the proximal covering to expose a wire or spring assembly. Alternatively, the whole proximal section could function as the platform. Essentially, to function as the platform for balloon catheter and stent, the devices should be sized with an outside diameter dimension that allows free movement of the catheter systems over it. Typical industry standards for coronary products permit free movement of devices over a 0.014″ or 0.018″ diameter while peripheral angioplasty applications use a 0.035″ OD.
  • [0146]
    Referring to FIG. 28 the tubing substrate 33 onto which the filter element is bonded can move between two stoppers 63 and 64, the stoppers are mounted on the primary crossing guidewire 2. The stoppers can be manufactured from a range of metallic or polymeric components, which will permit movement of the tubing substrate 33 between them. The stoppers may also be in the form of a step in the actual medical guidewire. A large variation in distances between stoppers 63 and 64 could be made to work in this application. The stoppers are sized to prevent movement of the tubing substrate either over or under them so that they act as a stop position for the tubing substrate in both their proximal and distal locations. The stoppers can be mounted onto the primary crossing guidewire by a number of known commercial technologies; these include soldering, welding, braising, crimping and adhesive bonding. The proximal stopper will be small enough in size to fit into the internal shaft of the delivery catheter. The filter element can move axially and rotationally independently of the guidewire. This allows for good wire movement and control of filter position. The filter position will be maintained during the exchange of catheters. Any commercially known available guidewire can be adapted accordingly and used with this technique.
  • [0147]
    [0147]FIG. 29 refers to an “olive” 65; the olive component can be manufactured from a range of metallic or polymeric components such as polymeric foams, plastics, stainless steel or metal. The olive will allow a smooth transition between the guidewire 2 and the pod 3 into which the filter element is loaded and also allows for easy positioning of the filter element within the pod. The olive can be directly attached to the guidewire or it may also be attached to a tubing substrate 33. The olive can be attached to the guidewire or tubing substrate by a range of known techniques such as adhesive bonding and soldering. The olive will work as required for a range of distances distal to the filter element. A wide number of shapes and sizes could be made to work as the olive component.
  • [0148]
    [0148]FIG. 30 refers to the filter element 1 when it is positioned in its most distal position. The filter element may achieve this position during loading or after deployment. The stopper element 64 prevents the filter element 1 from moving beyond it in the distal direction.
  • [0149]
    [0149]FIG. 31 illustrates the filter element in its most proximal location the filter element may achieve this position when deploying the device or after deployment. The stopper element 63 prevents the filter element 1 from moving beyond it in the proximal direction.
  • [0150]
    [0150]FIG. 32 refers to a floating distal tip in this case a stopper component 66 is placed proximal to the distal end of the filter. The most distal end of the filter being fixed to a marker band 70 or other suitable substrate. The marker band 70 is not fixed to the substrate tubing 33. This allows the distal end of the filter freedom of movement in the axial direction beyond the stopper component. The stopper component can be made to work using any shape or form so as to prevent movement of the distal end of the filter in the proximal direction beyond the point of fixturing of the stopper component. The stopper component may be manufactured from metals or polymeric material, it can be joined to the tubing substrate 33 by a number of existing technologies including adhesive bonding and soldering. The stopper component 65 will work when placed in any location between 50 and 70. A floating distal tip on the filter element will facilitate the loading of the filter element Into the loading pod as the filter can now extend in the axial direction and therefore be wrapped down over a greater length. This will reduce the loading force required and also reduce the profile of the loaded filter. The floating distal tip design will facilitate the loading of a large range of filter designs.
  • [0151]
    [0151]FIG. 33 refers to a concertina shaped filter with a floating distal tip. This filter geometry adds to the circumferential integrity of the filter and thus prevents the formation of creases along the length of the filter. “A” illustrates the filter as it will be when in position. “B” illustrates how the distal tip will extend in the axial direction when the filter element is loaded into a loading pod. The floating tip design can be used to accommodate the loading of many filter shape designs. For the fitter design shown a longer pod is needed to accommodate the increase in axial length of the filter element when loaded.
  • [0152]
    [0152]FIG. 34 refers to the floating distal tip design with a spring element 67 incorporated into the design. The spring is placed distal to the filter element. As previously illustrated in FIG. 33, the floating distal tip extends in the axial direction when loaded. The spring acts as a safety device when the filter is deployed and ensures the return of the floating distal tip to its primary location. The spring element will be soft enough to allow the distal tip to extend freely in the distal direction during loading but stiff enough to push the distal tip back to its primary location after deployment. The spring element can be manufactured from either a polymeric or metal component. The spring element can be mounted onto a substrate 33 and a stopper component used to prevent axial movement of the spring in the distal direction. Other methods of keeping the distal end of the spring element stationary could be used such as bonding, welding, crimping, soldering or crimping the distal end of the spring onto the substrate 33. This technique could also be made to work with the spring being part of the actual guidewire. There are many other configurations by which a return spring element may be incorporated into the filter as shown in FIGS. 35 and 36.
  • [0153]
    In FIG. 35 the spring element 67 is bonded to the substrate 33 at its proximal end and the distal end of the filter element is bonded to the spring shaft. This design allows the distal end of the filter element to extend in the distal direction. The extension length could be determined by either the positioning of a stopper 68 or the stiffness of the spring. When external forces are removed from the filter the spring will return the filter to its primary location. In FIG. 36 a shape memory alloy such as nitinol is used to return the filter to its primary location. The nitinol support frame 69 is fixed to the substrate 33 at its proximal end 70 and is floating at the distal end 71. The shape memory properties of the nitinol will ensure that the filter element returns to its primary location. This design can facilitate the use of any other commercially available or known shape memory alloys. This design could also be made to work using a spring component.
  • [0154]
    [0154]FIG. 37 again incorporates the floating distal tip design. The filter body 65 as previously illustrated in FIG. 27 is mounted onto a substrate 33. At the proximal end the stent is fixed to the substrate. The floating distal tip design allows the filter body 65 to extend in the distal direction. As the filter body 65 extends there is a reduction in its outside diameter and an increase in its overall length. There may or may not be need for a stopper 68 as the filter body 65 will extend up to its own elastic limit which is determined by its size and geometry. The shape memory function of the filter body 65 will cause the distal tip to return to its primary location when external forces are removed from it. The proximal end of the filter body 65 may be fixed to the substrate by a number of known technologies such as bonding, soldering or crimping.
  • [0155]
    [0155]FIG. 38 illustrates a number of different filter designs which could be made to work as embolic protection devices. These filter designs all work to reduce the longitudinal length of creases which may occur should the filter be oversized, therefore acting as crease breakers. Either ends of the filters shown could act as both proximal and distal ends for the filter. The filter body may be tubular or frusto-conical.
  • [0156]
    Referring to FIGS. 40 to 42 there is illustrated an embolic protection device according to the invention indicated generally by the reference number 100. The device 100 has a guidewire 101 with a proximal end 102 and a distal end 103. A tubular sleeve 104 is slidably mounted on the guidewire 101. A collapsible filter 105 is mounted on the sleeve 104, the filter 105 being movable between a collapsed stored position against the sleeve 104 and an expanded position as shown in the drawings extended outwardly of the sleeve 104 for deployment in a blood vessel.
  • [0157]
    The sleeve 104 is slidable on the guidewire 101 between a pair of spaced-apart end stops, namely an inner stop 106 and an outer stop which in this case is formed by a spring tip 107 at the distal end 103 of the guidewire 101.
  • [0158]
    The filter 105 comprises a mesh net 110 mounted over a collapsible support frame 111. The mesh net 110 is gathered into the sleeve 104 at each end, the net 110 being rigidly attached to a proximal end 112 of the sleeve 104 and the net 110 being attached to a collar 115 which is slidable along a distal end 114 of the sleeve 104 Thus the distal end of the net 110 is longitudinally slidable along the sleeve 104. The support frame 111 is also fixed at the proximal end 112 of the sleeve 104. A distal end 116 of the support frame 111 is not attached to the sleeve 104 and is thus also free to move longitudinally along the sleeve 104 to facilitate collapsing the support frame 111 against the sleeve 104. The support frame 111 is such that it is naturally expanded as shown in the drawings and can be collapsed inwardly against the sleeve 104 for loading in a catheter 118 or the like.
  • [0159]
    The filter 105 has large proximal inlet openings 117 and small distal outlet openings 119. The proximal inlet openings 117 allow blood and embolic material to enter the filter body, however, the distal outlet openings 119 allow through passage of blood but retain undesired embolic material within the filter body.
  • [0160]
    An olive guide 120 is mounted at a distal end of the sleeve 104 and has a cylindrical central portion 121 with tapered ends 122, 123. The distal end 112 may be an arrowhead configuration for smooth transition between the catheter and olive surfaces. The support frame 111 is shaped to provide a circumferential groove 125 in the filter net 110. If the filter is too large for a vessel, the net may crease and this groove 125 ensures any crease does not propagate along the fitter.
  • [0161]
    Enlarged openings are provided at a proximal end of the filter net 110 to allow ingress of blood and embolic material into an interior of the net 110.
  • [0162]
    In use, the filter 105 is mounted in a collapsed state within a distal end of the catheter 118 and delivered to a deployment site. When the filter is correctly positioned the catheter 118 is retracted allowing the support frame 111 to expand inflating the net 110 across the vessel in which the filter is mounted. Blood and emboli can enter the enlarged openings at a proximal end of the net 110. The blood Will pass through the net wall, however, the openings or pores in the net are sized so as to retain the embolic material. After use the catheter is delivered along the guidewire 101 and slid over the filter 105 engaging the proximal inlet end 112 first to close the openings and then gradually collapsing the net against the sleeve 104 as the catheter 118 advances over the filter 105. Once the filter 105 is fully loaded in the catheter 118, it can then be withdrawn.
  • [0163]
    It will be noted that a proximal end of the filter is fixed and a distal end of the filter is longitudinally movable along the sleeve to facilitate collapsing of the filter net.
  • [0164]
    Further, the catheter engages the proximal end of the filter net first thus closing the filter net inlet and preventing escape of embolic material from the filter net as the filter net is being collapsed.
  • [0165]
    Conveniently the tip of the catheter which forms a housing or pod for reception of the filter is of an elastic material which can radially expand to accommodate the filter with the captured embolic material. By correct choice of material, the same catheter or pod can be used to deploy and retrieve the filter. For deployment, the elastic material holds the filter in a tightly collapsed position to minimise the size of the catheter tip or pod. Then, when retrieving the filter, the catheter tip or pod is sufficiently elastic to accommodate the extra bulk of the filter due to the embolic material.
  • [0166]
    Also, the filter is not fast on the guidewire and thus accidental movement of the guidewire is accommodated without unintentionally moving the filter, for example, during exchange of medical devices or when changing catheters.
  • [0167]
    It will also be noted that the filter according to the invention does not have a sharp outer edge as with many umbrella type filters. Rather, the generally tubular filter shape is more accommodating of the interior walls of blood vessels.
  • [0168]
    Conveniently also when the filter has been deployed in a blood vessel, the catheter can be removed leaving a bare guidewire proximal to the filter for use with known devices such as balloon catheter and stent devices upstream of the filter.

Claims (42)

1. An embolic protection device comprising:
a collapsible filter element mounted on a filter carrier for delivery through a vascular system of a patient,
the filter element being movable between a collapsed stored position against the filter carrier for movement through the vascular system, and an expanded position for occluding a blood vessel such that blood passing through the blood vessel is delivered through the filter element,
the fitter element comprising a collapsible filter body having an inlet end and an outlet end,
the inlet end of the filter body having one or more inlet openings sized to allow blood and embolic material enter the filter body,
the outlet end of the filter body having a plurality of outlet openings sized to allow through passage of blood but to retain undesired embolic material within the filter body;
means for closing the inlet openings at the inlet end of the filter body, and
means for collapsing the filter body on the support.
2. A device as claimed in claim 1, wherein the means for closing the inlet openings comprises:
a tubular filter retrieval device having an open distal end for reception of the filter element,
said distal end being engagable with a proximal inlet end of the filter body to close the inlet openings and being slidable over the filter body from the inlet end to the outlet end to progressively collapse the filter body on the filter carrier and receive the filter body within the retrieval device.
3. A device as claimed in claim 1 wherein the collapsible filter element is slidably mounted on the filter carrier between a pair of spaced-apart stops on the filter carrier for axial movement of the filter element along the filter carrier between the stops.
4. A device as claimed in claim 3, wherein the filter element is rotatably mounted on the filter carrier.
5. A device as claimed in claim 3, wherein a sleeve is slidably mounted on the filter carrier between the stops, the length of the sleeve being less than the distance between the stops, the filter element being mounted on the sleeve.
6. A device as claimed in claim 1, wherein the filter element comprises:
a collapsible filter net mounted on the filter carrier,
the filter net being movable between a collapsed stored position against the filter carrier and an expanded position extending outwardly of the filter carrier for deployment across a blood vessel
7. A device as claimed in claim 2, wherein the tubular filter retrieval device comprises a catheter slidable along the filter carrier, an open distal end of the catheter forming a housing for reception of the filter element.
8. A device as claimed in claim 1, wherein a proximal inlet nd of the filter body is fixed to the filter carrier and a distal end of the filter body is slidably mounted on the filter carrier.
9. A device claimed in claims 1 wherein a filter support frame is mounted on the filter carrier, the support frame being movable between a collapsed position along the filter carrier and an extended outwardly projecting position to support the filter body in the expanded position.
10. A device as claimed in claim 9 wherein the filter support frame is fixed on the filter carrier at a proximal end of the filter body, and the filter support frame slidably engages the filter carrier at a distal end of the fitter body.
11. A device as claimed in claim 9 wherein the filter support frame is biased into a normally extend position.
12. A device as claimed in claim 9 wherein a circumferential groove is provided in the filter body intermediate the ends of the filter body.
13. A device as claimed in claim 1, wherein a guide olive is provided on the filter carrier distally of the fitter body, the guide olive having a cylindrical body with a tapered distal end, the cylindrical body being engagable within a distal end of a deployment catheter, said tapered distal end projecting outwardly of the deployment catheter to provide a smooth transition between the catheter and the filter carrier.
14. A device as claimed in claim 1 wherein the filter element includes storage means to store captured undesired embolic material in the filter element.
15. A device as claimed in claim 14 wherein the storage means comprises additional storage pathways within the filter element.
16. A device as claimed in claim 1 wherein the filter element defines a three dimensional matrix.
17. A device as claimed in claim 16 wherein the filter element is of a polymeric porous structure.
18. A device as claimed in claim 16 wherein the matrix comprises a porous structure dimensioned to entrap embolic material ranging in siZe from 100 microns to 3500 microns.
19. A device as claimed in claim 1 wherein the filter element has a distal end which is tapered such that there is a smooth transition in lateral stiffness to improve the manoeuvrability of the filter element in the vascular system.
20. A device as claimed in claim 1 wherein the filter element has a soft distal portion to aid in atraumatic transport through the vascular system.
21. A device as claimed in claim 1 wherein the filter element has a tapered proximal end to facilitate retrieval by a removal catheter.
22. A device as claimed in claim 1 wherein the filter element has hlet holes that close on pulling back into a retrieval catheter to ensure retention of any collected emboli.
23. A device as claimed claim 1 having means for placing the device over a medical guidewire.
24. A device as claimed in claim 23 which may be placed under a balloon or stent delivery catheter.
25. A device as claimed in any proceeding claim including a delivery catheter in which an external sheath is engagable with the filter element or filter carrier to provide push during delivery and is removable to allow maximum space in the vascular cross-section during an interventional procedure.
26. A device as claimed in claim 25 wherein the external sheath is joined to the filter element or filter carrier by a joining means.
27. A device as claimed in claim 25 wherein the delivery catheter has a central lumen for at least part of it's length to allow it to track over a steerable guidewire.
28. A device as claimed in claim 25, wherein the external sheath is sufficiently long to extend to the outside of the vasculature and is removable proximally to release the filter element from the catheter.
29. A device as claimed in claim 25, wherein the delivery catheter has an external covering which extends beyond the push element to define a filter retention sleeve.
30. A device a claimed in claim 1 wherein the filter element is mounted on a collapsible support frame which is removable between a collapsed position for deployment and an extended in-use position, means being provided for retaining the support structure in the collapsed position.
31. A device as claimed in claim 30 wherein the support frame is formed from a shape memory elastic memory material.
32. A device as claimed in claim 1 wherein the filter element has an associated support structure with a pre-shaped spiral arrangement such that it provides radial support to the filter element.
33. A device as claimed in claim 1 wherein the filter has a support structure adapted to fold into the collapsed position when pulled into a retrieval catheter.
34. A device as claimed in claim 1 wherein the filter element comprises a flexible shaped polymeric component.
35. A device as claimed in claim 1 wherein the filter element is directly bonded onto a steerable medical guide wire incorporating slidable sheath that is movable to deploy the filter.
36. A device as claimed in claim 1 incorporating a medical guidewire with a flexible segment of wire distal to the filter so as to provide steerability of the wire particularly prior to it being deployed.
37. A device as claimed in claim 1 incorporating a medical guide wire with a soft distal segment so as to provide a tip section that will be atraumatic.
38. A device as claimed in claim 1 having a filter element which permits the incorporation of a medical guide wire in or near the outer wall of the filter element to facilitate the incorporation of large inlet holes on the proximal inlet end of the filter element.
39. A device as claimed in claim wherein the filter element comprises a mesh work structure with large proximal inlet holes and small distal outlet holes wherein the mesh structure is collapsible into a small diameter delivery catheter and is expandable upon deployment to a shape which is remembered by the mesh structure either through shape memory characteristics or elastic memory characteristics.
40. A device as claimed in claim 1 wherein the filter element comprises a braided fibrous meshwork.
41. A filter retrieval system for use with the device as claimed in any proceeding claim comprising a longitudinal catheter with a deformable tip to assist the pull back of the filter into it.
42. A method for the capture and removal of embolic material from a blood vessel during an interventional procedure comprising the steps:
preparing an embolic protection device comprising guidewire having a proximal end and a distal end, a collapsible filter element mounted adjacent the distal end of the guidewire, the filter element being movable between a collapsed stored position against the guidewire and an expanded position extending laterally outwardly of the guidewire,
sliding a catheter along the guidewire and over the filter element from a proximal inlet end of the fiter to collapse and house the filter in a distal end of the catheter,
introducing the distal end of the catheter into the vascular system of a patient,
positioning the distal end at a desired location in the blood vessel,
holding the guidewire and retracting the catheter to release the filter element from the catheter into the expanded position,
filtering blood in the vessel during the interventional procedure,
after the interventional procedure advancing a retrieval catheter along the guidewire to engage a proximal inlet end of the filter,
collapsing the filter into the distal end of the catheter, and
withdrawing the catheter from the patient.
US10410606 1997-11-07 2003-04-10 Embolic protection device Abandoned US20040039411A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IE970789 1997-11-07
IE970789 1997-11-07
IE980267 1998-04-08
IE980267 1998-04-08
US09188472 US6336934B1 (en) 1997-11-07 1998-11-09 Embolic protection device
US09921596 US6432122B1 (en) 1997-11-07 2001-08-06 Embolic protection device
US10058828 US7901426B2 (en) 1997-11-07 2002-01-30 Embolic protection device
US10410606 US20040039411A1 (en) 1997-11-07 2003-04-10 Embolic protection device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10410606 US20040039411A1 (en) 1997-11-07 2003-04-10 Embolic protection device
US11073936 US7837701B2 (en) 1997-11-07 2005-03-08 Embolic protection device

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US10058828 Continuation US7901426B2 (en) 1997-11-07 2002-01-30 Embolic protection device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11073936 Continuation US7837701B2 (en) 1997-11-07 2005-03-08 Embolic protection device

Publications (1)

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US20040039411A1 true true US20040039411A1 (en) 2004-02-26

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US09188472 Active US6336934B1 (en) 1997-11-07 1998-11-09 Embolic protection device
US09921596 Active US6432122B1 (en) 1997-11-07 2001-08-06 Embolic protection device
US09938548 Active 2018-11-11 US6645224B2 (en) 1997-11-07 2001-08-27 Embolic protection device
US10058828 Active 2026-04-19 US7901426B2 (en) 1997-11-07 2002-01-30 Embolic protection device
US10396704 Abandoned US20040073198A1 (en) 1997-11-07 2003-03-26 Embolic protection device
US10410606 Abandoned US20040039411A1 (en) 1997-11-07 2003-04-10 Embolic protection device
US10442259 Active 2019-08-29 US7662165B2 (en) 1997-11-07 2003-05-21 Embolic protection device
US10442115 Active 2019-02-17 US7785342B2 (en) 1997-11-07 2003-05-21 Embolic protection device
US11011789 Active 2019-07-09 US7842063B2 (en) 1997-11-07 2004-12-15 Embolic protection device
US11068529 Abandoned US20050209635A1 (en) 1997-11-07 2005-03-01 Embolic protection device
US11074017 Active 2022-03-18 US8057504B2 (en) 1997-11-07 2005-03-08 Embolic protection device
US11073936 Active 2022-03-08 US7837701B2 (en) 1997-11-07 2005-03-08 Embolic protection device
US11115398 Abandoned US20060095070A1 (en) 1997-11-07 2005-04-27 Embolic portection device
US11325480 Active US7510565B2 (en) 1997-11-07 2006-01-05 Embolic protection device
US11389544 Abandoned US20060259069A1 (en) 1997-11-07 2006-03-27 Embolic protection device
US11610144 Abandoned US20070162069A1 (en) 1997-11-07 2006-12-13 Embolic protection device
US11610167 Abandoned US20070173884A1 (en) 1997-11-07 2006-12-13 Embolic protection device
US11610208 Active 2022-11-09 US8603131B2 (en) 1997-11-07 2006-12-13 Embolic protection device
US11613480 Abandoned US20080188884A1 (en) 1997-11-07 2006-12-20 Embolic protection device
US11614502 Active 2020-12-25 US8216270B2 (en) 1997-11-07 2006-12-21 Embolic protection device
US11617249 Active 2021-07-28 US7833242B2 (en) 1997-11-07 2006-12-28 Embolic protection device
US11762283 Active 2020-03-17 US8221448B2 (en) 1997-11-07 2007-06-13 Embolic protection device
US11762462 Active 2020-04-02 US8226678B2 (en) 1997-11-07 2007-06-13 Embolic protection device
US11762440 Active 2020-01-17 US8430901B2 (en) 1997-11-07 2007-06-13 Embolic protection device
US12336572 Abandoned US20090099593A1 (en) 1997-11-07 2008-12-17 Embolic protection device
US12366249 Abandoned US20090143814A1 (en) 1997-11-07 2009-02-05 Embolic protection device
US13183583 Active 2019-03-22 US8852226B2 (en) 1997-11-07 2011-07-15 Vascular device for use during an interventional procedure

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US09188472 Active US6336934B1 (en) 1997-11-07 1998-11-09 Embolic protection device
US09921596 Active US6432122B1 (en) 1997-11-07 2001-08-06 Embolic protection device
US09938548 Active 2018-11-11 US6645224B2 (en) 1997-11-07 2001-08-27 Embolic protection device
US10058828 Active 2026-04-19 US7901426B2 (en) 1997-11-07 2002-01-30 Embolic protection device
US10396704 Abandoned US20040073198A1 (en) 1997-11-07 2003-03-26 Embolic protection device

Family Applications After (21)

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US10442259 Active 2019-08-29 US7662165B2 (en) 1997-11-07 2003-05-21 Embolic protection device
US10442115 Active 2019-02-17 US7785342B2 (en) 1997-11-07 2003-05-21 Embolic protection device
US11011789 Active 2019-07-09 US7842063B2 (en) 1997-11-07 2004-12-15 Embolic protection device
US11068529 Abandoned US20050209635A1 (en) 1997-11-07 2005-03-01 Embolic protection device
US11074017 Active 2022-03-18 US8057504B2 (en) 1997-11-07 2005-03-08 Embolic protection device
US11073936 Active 2022-03-08 US7837701B2 (en) 1997-11-07 2005-03-08 Embolic protection device
US11115398 Abandoned US20060095070A1 (en) 1997-11-07 2005-04-27 Embolic portection device
US11325480 Active US7510565B2 (en) 1997-11-07 2006-01-05 Embolic protection device
US11389544 Abandoned US20060259069A1 (en) 1997-11-07 2006-03-27 Embolic protection device
US11610144 Abandoned US20070162069A1 (en) 1997-11-07 2006-12-13 Embolic protection device
US11610167 Abandoned US20070173884A1 (en) 1997-11-07 2006-12-13 Embolic protection device
US11610208 Active 2022-11-09 US8603131B2 (en) 1997-11-07 2006-12-13 Embolic protection device
US11613480 Abandoned US20080188884A1 (en) 1997-11-07 2006-12-20 Embolic protection device
US11614502 Active 2020-12-25 US8216270B2 (en) 1997-11-07 2006-12-21 Embolic protection device
US11617249 Active 2021-07-28 US7833242B2 (en) 1997-11-07 2006-12-28 Embolic protection device
US11762283 Active 2020-03-17 US8221448B2 (en) 1997-11-07 2007-06-13 Embolic protection device
US11762462 Active 2020-04-02 US8226678B2 (en) 1997-11-07 2007-06-13 Embolic protection device
US11762440 Active 2020-01-17 US8430901B2 (en) 1997-11-07 2007-06-13 Embolic protection device
US12336572 Abandoned US20090099593A1 (en) 1997-11-07 2008-12-17 Embolic protection device
US12366249 Abandoned US20090143814A1 (en) 1997-11-07 2009-02-05 Embolic protection device
US13183583 Active 2019-03-22 US8852226B2 (en) 1997-11-07 2011-07-15 Vascular device for use during an interventional procedure

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JP (2) JP4328888B2 (en)
KR (1) KR20010052095A (en)
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DE (5) DE29880158U1 (en)
EP (2) EP1752112B1 (en)
ES (2) ES2300124T3 (en)
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Cited By (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030004536A1 (en) * 2001-06-29 2003-01-02 Boylan John F. Variable thickness embolic filtering devices and method of manufacturing the same
US20030032941A1 (en) * 2001-08-13 2003-02-13 Boyle William J. Convertible delivery systems for medical devices
US20030065354A1 (en) * 2001-09-28 2003-04-03 Boyle William J. Embolic filtering devices
US20030120303A1 (en) * 2001-12-21 2003-06-26 Boyle William J. Flexible and conformable embolic filtering devices
US20030212361A1 (en) * 1999-12-30 2003-11-13 Boyle William J. Embolic protection devices
US20040064099A1 (en) * 2002-09-30 2004-04-01 Chiu Jessica G. Intraluminal needle injection substance delivery system with filtering capability
US20040068288A1 (en) * 1999-12-23 2004-04-08 Olin Palmer Intravascular device and system
US20040088002A1 (en) * 2001-04-30 2004-05-06 Boyle William J. Deployment and recovery control systems for embolic protection devices
US20040093009A1 (en) * 2002-09-30 2004-05-13 Denison Andy E. Embolic filtering devices
US20040167568A1 (en) * 1999-12-30 2004-08-26 Boyle William J. Embolic protection devices
US20040167567A1 (en) * 2001-03-23 2004-08-26 Cano Gerald G. Method and apparatus for capturing objects beyond an operative site in medical procedures
US20040172055A1 (en) * 2003-02-27 2004-09-02 Huter Scott J. Embolic filtering devices
US20050004595A1 (en) * 2003-02-27 2005-01-06 Boyle William J. Embolic filtering devices
US20050075663A1 (en) * 2001-11-27 2005-04-07 Boyle William J. Offset proximal cage for embolic filtering devices
US20050182441A1 (en) * 2002-06-26 2005-08-18 Denison Andy E. Embolic filtering devices for bifurcated vessels
US20050222583A1 (en) * 2000-11-09 2005-10-06 Cano Gerald G Apparatus for capturing objects beyond an operative site utilizing a capture device delivered on a medical guide wire
US20050228439A1 (en) * 2001-06-01 2005-10-13 Andrews Christopher C Delivery and recovery system for embolic protection system
US20060095069A1 (en) * 2000-07-13 2006-05-04 Shah Niraj A Embolic protection guide wire
US20060129183A1 (en) * 2000-12-19 2006-06-15 Advanced Cardiovascular Systems Sheathless embolic protection system
WO2006104910A1 (en) * 2005-03-29 2006-10-05 Boston Scientific Limited Methods and apparatuses for disposition of a medical device onto an elongate medical device
US20070088382A1 (en) * 2005-10-13 2007-04-19 Bei Nianjiong J Embolic protection recovery catheter assembly
US20070149997A1 (en) * 2002-10-31 2007-06-28 Muller Paul F Single-wire expandable cages for embolic filtering devices
US20070162071A1 (en) * 2004-03-19 2007-07-12 Burkett David H Locking component for an embolic filter assembly
US20070276429A1 (en) * 2001-06-29 2007-11-29 Advanced Cardiovascular Systems, Inc. Filter device for embolic protection systems
US20080215084A1 (en) * 2000-10-17 2008-09-04 Advanced Cardiovascular Systems, Inc. Delivery systems for embolic filter devices
US20100004674A1 (en) * 1999-12-30 2010-01-07 Advanced Cardiovascular Systems, Inc. Device for, and method of, blocking emboli in vessels such as blood arteries
US7815660B2 (en) 2002-09-30 2010-10-19 Advanced Cardivascular Systems, Inc. Guide wire with embolic filtering attachment
US7842064B2 (en) 2001-08-31 2010-11-30 Advanced Cardiovascular Systems, Inc. Hinged short cage for an embolic protection device
US7867273B2 (en) 2007-06-27 2011-01-11 Abbott Laboratories Endoprostheses for peripheral arteries and other body vessels
US7892251B1 (en) 2003-11-12 2011-02-22 Advanced Cardiovascular Systems, Inc. Component for delivering and locking a medical device to a guide wire
US7959647B2 (en) 2001-08-30 2011-06-14 Abbott Cardiovascular Systems Inc. Self furling umbrella frame for carotid filter
US8137377B2 (en) 1999-12-23 2012-03-20 Abbott Laboratories Embolic basket
US8142442B2 (en) 1999-12-23 2012-03-27 Abbott Laboratories Snare
US8216209B2 (en) 2007-05-31 2012-07-10 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
US9259305B2 (en) 2005-03-31 2016-02-16 Abbott Cardiovascular Systems Inc. Guide wire locking mechanism for rapid exchange and other catheter systems
US9295393B2 (en) 2012-11-09 2016-03-29 Elwha Llc Embolism deflector
US9579116B1 (en) 2015-08-06 2017-02-28 Kp Medcure, Inc. Axial lengthening thrombus capture system
US9744024B2 (en) 2015-08-06 2017-08-29 Kp Medcure, Inc. Axial lengthening thrombus capture system

Families Citing this family (471)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10504738A (en) 1994-07-08 1998-05-12 マイクロベナ コーポレイション Forming method and vascular embolization device of the medical device
US6991641B2 (en) * 1999-02-12 2006-01-31 Cordis Corporation Low profile vascular filter system
US20020138094A1 (en) * 1999-02-12 2002-09-26 Thomas Borillo Vascular filter system
DE69830340D1 (en) 1997-02-03 2005-06-30 Angioguard Inc vascular filters
WO1998039053A1 (en) * 1997-03-06 1998-09-11 Scimed Life Systems, Inc. Distal protection device and method
US6726703B2 (en) 2000-11-27 2004-04-27 Scimed Life Systems, Inc. Distal protection device and method
US5911734A (en) 1997-05-08 1999-06-15 Embol-X, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
US6761727B1 (en) 1997-06-02 2004-07-13 Medtronic Ave, Inc. Filter assembly
DE29880158U1 (en) * 1997-11-07 2000-11-30 Salviac Ltd Embolic protection device
US7491216B2 (en) * 1997-11-07 2009-02-17 Salviac Limited Filter element with retractable guidewire tip
CA2323655A1 (en) 1998-04-02 1999-10-14 Salviac Limited Delivery catheter
EP1087724A1 (en) * 1998-06-16 2001-04-04 Mind-Guard Ltd. Implantable blood filtering device
US6755856B2 (en) 1998-09-05 2004-06-29 Abbott Laboratories Vascular Enterprises Limited Methods and apparatus for stenting comprising enhanced embolic protection, coupled with improved protection against restenosis and thrombus formation
US7314477B1 (en) 1998-09-25 2008-01-01 C.R. Bard Inc. Removable embolus blood clot filter and filter delivery unit
US7128073B1 (en) 1998-11-06 2006-10-31 Ev3 Endovascular, Inc. Method and device for left atrial appendage occlusion
US7044134B2 (en) 1999-11-08 2006-05-16 Ev3 Sunnyvale, Inc Method of implanting a device in the left atrial appendage
US6171327B1 (en) 1999-02-24 2001-01-09 Scimed Life Systems, Inc. Intravascular filter and method
US6918921B2 (en) * 1999-05-07 2005-07-19 Salviac Limited Support frame for an embolic protection device
WO2000067666A1 (en) * 1999-05-07 2000-11-16 Salviac Limited Improved filter element for embolic protection device
WO2000067667A1 (en) 1999-05-07 2000-11-16 Salviac Limited A filter element with retractable guidewire tip
US20020058911A1 (en) 1999-05-07 2002-05-16 Paul Gilson Support frame for an embolic protection device
JP2002543877A (en) * 1999-05-07 2002-12-24 サルヴィアック・リミテッド The embolic protection device
WO2000067665A1 (en) 1999-05-07 2000-11-16 Salviac Limited Support frame for embolic protection device
US6964672B2 (en) * 1999-05-07 2005-11-15 Salviac Limited Support frame for an embolic protection device
WO2000067829A1 (en) 1999-05-07 2000-11-16 Salviac Limited Improvements in medical guidewires
US6468291B2 (en) * 1999-07-16 2002-10-22 Baff Llc Emboli filtration system having integral strut arrangement and methods of use
US6179859B1 (en) * 1999-07-16 2001-01-30 Baff Llc Emboli filtration system and methods of use
US20030150821A1 (en) * 1999-07-16 2003-08-14 Bates Mark C. Emboli filtration system and methods of use
US6203561B1 (en) 1999-07-30 2001-03-20 Incept Llc Integrated vascular device having thrombectomy element and vascular filter and methods of use
US6179861B1 (en) 1999-07-30 2001-01-30 Incept Llc Vascular device having one or more articulation regions and methods of use
WO2001008742A9 (en) 1999-07-30 2002-09-06 Incept Llc Vascular filter having articulation region and methods of use in the ascending aorta
US6214026B1 (en) 1999-07-30 2001-04-10 Incept Llc Delivery system for a vascular device with articulation region
USRE43882E1 (en) 1999-07-30 2012-12-25 Incept, Llc Vascular device for emboli, thrombus and foreign body removal and methods of use
US7229463B2 (en) * 1999-07-30 2007-06-12 Angioguard, Inc. Vascular filter system for cardiopulmonary bypass
US6530939B1 (en) * 1999-07-30 2003-03-11 Incept, Llc Vascular device having articulation region and methods of use
US7229462B2 (en) * 1999-07-30 2007-06-12 Angioguard, Inc. Vascular filter system for carotid endarterectomy
US6602271B2 (en) 2000-05-24 2003-08-05 Medtronic Ave, Inc. Collapsible blood filter with optimal braid geometry
US6346116B1 (en) * 1999-08-03 2002-02-12 Medtronic Ave, Inc. Distal protection device
WO2001012082A1 (en) 1999-08-12 2001-02-22 Salviac Limited Retrieval device
DE69939753D1 (en) * 1999-08-27 2008-11-27 Ev3 Inc Sliding vascular filter
DE29916162U1 (en) * 1999-09-14 2000-01-13 Cormedics Gmbh Vascular filter system
US6325815B1 (en) * 1999-09-21 2001-12-04 Microvena Corporation Temporary vascular filter
US6939361B1 (en) * 1999-09-22 2005-09-06 Nmt Medical, Inc. Guidewire for a free standing intervascular device having an integral stop mechanism
US8414543B2 (en) * 1999-10-22 2013-04-09 Rex Medical, L.P. Rotational thrombectomy wire with blocking device
US6217589B1 (en) 1999-10-27 2001-04-17 Scimed Life Systems, Inc. Retrieval device made of precursor alloy cable and method of manufacturing
US6371971B1 (en) * 1999-11-15 2002-04-16 Scimed Life Systems, Inc. Guidewire filter and methods of use
FR2801493B1 (en) * 1999-11-26 2003-10-03 Braun Celsa Sa Method of manufacturing an integral blood filter
US6623450B1 (en) 1999-12-17 2003-09-23 Advanced Cardiovascular Systems, Inc. System for blocking the passage of emboli through a body vessel
US6443971B1 (en) 1999-12-21 2002-09-03 Advanced Cardiovascular Systems, Inc. System for, and method of, blocking the passage of emboli through a vessel
US6290710B1 (en) 1999-12-29 2001-09-18 Advanced Cardiovascular Systems, Inc. Embolic protection device
WO2002043595A3 (en) * 2000-11-28 2003-12-18 Advanced Cardiovascular System Embolic protection devices
US6383206B1 (en) * 1999-12-30 2002-05-07 Advanced Cardiovascular Systems, Inc. Embolic protection system and method including filtering elements
US6511503B1 (en) * 1999-12-30 2003-01-28 Advanced Cardiovascular Systems, Inc. Catheter apparatus for treating occluded vessels and filtering embolic debris and method of use
US6702834B1 (en) 1999-12-30 2004-03-09 Advanced Cardiovascular Systems, Inc. Embolic protection devices
US6361546B1 (en) * 2000-01-13 2002-03-26 Endotex Interventional Systems, Inc. Deployable recoverable vascular filter and methods for use
US6540768B1 (en) 2000-02-09 2003-04-01 Cordis Corporation Vascular filter system
US6485500B1 (en) 2000-03-21 2002-11-26 Advanced Cardiovascular Systems, Inc. Emboli protection system
GB0127195D0 (en) * 2000-04-20 2002-01-02 Salviac Ltd An embolic protection system
EP1149566A3 (en) * 2000-04-24 2003-08-06 Cordis Corporation Vascular filter systems with guidewire and capture mechanism
US7321677B2 (en) * 2000-05-09 2008-01-22 Paieon Inc. System and method for three-dimensional reconstruction of an artery
US6520978B1 (en) 2000-05-15 2003-02-18 Intratherapeutics, Inc. Emboli filter
US6645221B1 (en) * 2000-05-30 2003-11-11 Zuli, Holdings Ltd. Active arterial embolization filter
US7555333B2 (en) * 2000-06-19 2009-06-30 University Of Washington Integrated optical scanning image acquisition and display
WO2001097697A1 (en) * 2000-06-22 2001-12-27 White Geoffrey H Method and apparatus for performing percutaneous thromboembolectomies
US6565591B2 (en) 2000-06-23 2003-05-20 Salviac Limited Medical device
DE60126084T2 (en) * 2000-06-23 2007-08-09 Salviac Ltd. Filter element for an embolic protection device
US6679902B1 (en) 2000-07-19 2004-01-20 Advanced Cardiovascular Systems, Inc. Reduced profile delivery sheath for use in interventional procedures
US6740061B1 (en) 2000-07-28 2004-05-25 Ev3 Inc. Distal protection device
US6544279B1 (en) 2000-08-09 2003-04-08 Incept, Llc Vascular device for emboli, thrombus and foreign body removal and methods of use
US6485501B1 (en) 2000-08-11 2002-11-26 Cordis Corporation Vascular filter system with guidewire and capture mechanism
JP2002078809A (en) * 2000-09-07 2002-03-19 Shutaro Satake Balloon catheter for electrically isolating pulmonary vein
US6511496B1 (en) 2000-09-12 2003-01-28 Advanced Cardiovascular Systems, Inc. Embolic protection device for use in interventional procedures
DE10049812B4 (en) * 2000-10-09 2004-06-03 Universitätsklinikum Freiburg Apparatus for filtering of macroscopic particles from the blood stream to the local removal of an aortic valve on the human or animal heart
US6616680B1 (en) * 2000-11-01 2003-09-09 Joseph M. Thielen Distal protection and delivery system and method
DE60123990D1 (en) * 2000-11-03 2006-11-30 Cook Inc Medical cross device
US7713275B2 (en) 2000-11-03 2010-05-11 Cook Incorporated Medical grasping device
US7727253B2 (en) * 2000-11-03 2010-06-01 Cook Incorporated Medical grasping device having embolic protection
US7753917B2 (en) * 2000-11-03 2010-07-13 Cook Incorporated Medical grasping device
US6663651B2 (en) 2001-01-16 2003-12-16 Incept Llc Systems and methods for vascular filter retrieval
US6689151B2 (en) * 2001-01-25 2004-02-10 Scimed Life Systems, Inc. Variable wall thickness for delivery sheath housing
US20020128680A1 (en) * 2001-01-25 2002-09-12 Pavlovic Jennifer L. Distal protection device with electrospun polymer fiber matrix
US6979343B2 (en) * 2001-02-14 2005-12-27 Ev3 Inc. Rolled tip recovery catheter
US6569184B2 (en) 2001-02-27 2003-05-27 Advanced Cardiovascular Systems, Inc. Recovery system for retrieving an embolic protection device
US6974468B2 (en) * 2001-02-28 2005-12-13 Scimed Life Systems, Inc. Filter retrieval catheter
US6562058B2 (en) 2001-03-02 2003-05-13 Jacques Seguin Intravascular filter system
US6579302B2 (en) 2001-03-06 2003-06-17 Cordis Corporation Total occlusion guidewire device
EP1539031B1 (en) * 2002-09-19 2013-01-02 Memory Metal Holland BV Vascular filter with improved strength and flexibility
US6706055B2 (en) * 2001-04-03 2004-03-16 Medtronic Ave Inc. Guidewire apparatus for temporary distal embolic protection
US7044958B2 (en) 2001-04-03 2006-05-16 Medtronic Vascular, Inc. Temporary device for capturing embolic material
US20020161395A1 (en) * 2001-04-03 2002-10-31 Nareak Douk Guide wire apparatus for prevention of distal atheroembolization
US6866677B2 (en) 2001-04-03 2005-03-15 Medtronic Ave, Inc. Temporary intraluminal filter guidewire and methods of use
US6818006B2 (en) 2001-04-03 2004-11-16 Medtronic Vascular, Inc. Temporary intraluminal filter guidewire
DE60210059D1 (en) 2001-04-17 2006-05-11 Salviac Ltd catheter
US20020188314A1 (en) * 2001-06-07 2002-12-12 Microvena Corporation Radiopaque distal embolic protection device
US6962598B2 (en) * 2001-07-02 2005-11-08 Rubicon Medical, Inc. Methods, systems, and devices for providing embolic protection
ES2264468T3 (en) 2001-07-13 2007-01-01 B. Braun Medical Sas Vascular protection system and apparatus so equipped angioplasty.
FR2827152B1 (en) * 2001-07-13 2004-03-05 Braun Medical vascular protection system double branches
US7029488B2 (en) * 2001-08-22 2006-04-18 Gore Enterprise Holdings, Inc. Mechanical thrombectomy device for use in cerebral vessels
US6616682B2 (en) * 2001-09-19 2003-09-09 Jomed Gmbh Methods and apparatus for distal protection during a medical procedure
US6878151B2 (en) * 2001-09-27 2005-04-12 Scimed Life Systems, Inc. Medical retrieval device
US20030060843A1 (en) * 2001-09-27 2003-03-27 Don Boucher Vascular filter system with encapsulated filter
CA2456918C (en) 2001-09-28 2011-02-22 Edward Parsonage Medical devices comprising nanocomposites
DE60138969D1 (en) * 2001-09-28 2009-07-23 Kanji Inoue Tool to capture free thrombi
US20030078614A1 (en) * 2001-10-18 2003-04-24 Amr Salahieh Vascular embolic filter devices and methods of use therefor
US6887257B2 (en) 2001-10-19 2005-05-03 Incept Llc Vascular embolic filter exchange devices and methods of use thereof
US7438710B2 (en) * 2001-11-07 2008-10-21 Anderson Kent D Distal protection device with local drug infusion by physician to maintain patency
JP4350515B2 (en) 2001-11-09 2009-10-21 ルビコン・メデイカル・インコーポレイテツド Stent delivery system
US6837898B2 (en) 2001-11-30 2005-01-04 Advanced Cardiovascular Systems, Inc. Intraluminal delivery system for an attachable treatment device
EP1455686A2 (en) * 2001-12-21 2004-09-15 Salviac Limited A support frame for an embolic protection device
US7322958B2 (en) * 2001-12-27 2008-01-29 Wholey Mark H Apparatus for thromboembolic protection
US6958074B2 (en) 2002-01-07 2005-10-25 Cordis Corporation Releasable and retrievable vascular filter system
US7344549B2 (en) * 2002-01-31 2008-03-18 Advanced Cardiovascular Systems, Inc. Expandable cages for embolic filtering devices
US9204956B2 (en) 2002-02-20 2015-12-08 C. R. Bard, Inc. IVC filter with translating hooks
WO2003073961A1 (en) * 2002-03-05 2003-09-12 Salviac Limited System with embolic filter and retracting snare
WO2003075793A1 (en) * 2002-03-06 2003-09-18 Boston Scientific Limited Medical retrieval device
US6773448B2 (en) 2002-03-08 2004-08-10 Ev3 Inc. Distal protection devices having controllable wire motion
US20030176886A1 (en) * 2002-03-12 2003-09-18 Wholey Mark H. Vascular catheter with expanded distal tip for receiving a thromboembolic protection device and method of use
US20030199112A1 (en) * 2002-03-22 2003-10-23 Applied Materials, Inc. Copper wiring module control
US20030187495A1 (en) 2002-04-01 2003-10-02 Cully Edward H. Endoluminal devices, embolic filters, methods of manufacture and use
DE60324787D1 (en) * 2002-05-10 2009-01-02 Salviac Ltd System for filtering of emboli
WO2003094790A3 (en) * 2002-05-13 2004-04-08 Salviac Ltd Catheter system with procedural catheter and embolic proctection system
US7399307B2 (en) 2002-05-14 2008-07-15 Bacchus Vascular, Inc. Apparatus and method for removing occlusive material within blood vessels
US7001406B2 (en) * 2002-05-23 2006-02-21 Scimed Life Systems Inc. Cartridge embolic protection filter and methods of use
US7959584B2 (en) * 2002-05-29 2011-06-14 Boston Scientific Scimed, Inc. Dedicated distal protection guidewires
US7172614B2 (en) * 2002-06-27 2007-02-06 Advanced Cardiovascular Systems, Inc. Support structures for embolic filtering devices
US7166120B2 (en) * 2002-07-12 2007-01-23 Ev3 Inc. Catheter with occluding cuff
DE10233085B4 (en) * 2002-07-19 2014-02-20 Dendron Gmbh Stent with guidewire
US7479151B2 (en) * 2002-08-05 2009-01-20 Gardia Medical Ltd. Embolism filter with self-deployable guidewire stop
EP1402826B1 (en) 2002-08-20 2013-06-12 Nipro Corporation Thrombus capture catheter
US7056328B2 (en) * 2002-09-18 2006-06-06 Arnott Richard J Apparatus for capturing objects beyond an operative site utilizing a capture device delivered on a medical guide wire
US8468678B2 (en) 2002-10-02 2013-06-25 Boston Scientific Scimed, Inc. Expandable retrieval device
US7998163B2 (en) * 2002-10-03 2011-08-16 Boston Scientific Scimed, Inc. Expandable retrieval device
US20040093012A1 (en) 2002-10-17 2004-05-13 Cully Edward H. Embolic filter frame having looped support strut elements
JP2007521843A (en) 2003-05-15 2007-08-09 バイオメリクス コーポレーション Reticulated elastomeric matrix, their preparation and use in implantable devices
US20040102789A1 (en) * 2002-11-22 2004-05-27 Scimed Life Systems, Inc. Selectively locking device
US20040111110A1 (en) * 2002-12-05 2004-06-10 Melker Richard J Temporary peripheral blood filtration methods to reduce or prevent post-surgery related cognitive dysfunction
US7128752B2 (en) * 2002-12-23 2006-10-31 Syntheon, Llc Emboli and thrombi filter device and method of using the same
US7625389B2 (en) * 2002-12-30 2009-12-01 Boston Scientific Scimed, Inc. Embolic protection device
US20040138693A1 (en) * 2003-01-14 2004-07-15 Scimed Life Systems, Inc. Snare retrievable embolic protection filter with guidewire stopper
US7323001B2 (en) 2003-01-30 2008-01-29 Ev3 Inc. Embolic filters with controlled pore size
US7220271B2 (en) * 2003-01-30 2007-05-22 Ev3 Inc. Embolic filters having multiple layers and controlled pore size
US20040153119A1 (en) * 2003-01-30 2004-08-05 Kusleika Richard S. Embolic filters with a distal loop or no loop
US6878291B2 (en) * 2003-02-24 2005-04-12 Scimed Life Systems, Inc. Flexible tube for cartridge filter
US7740644B2 (en) 2003-02-24 2010-06-22 Boston Scientific Scimed, Inc. Embolic protection filtering device that can be adapted to be advanced over a guidewire
US20040167566A1 (en) * 2003-02-24 2004-08-26 Scimed Life Systems, Inc. Apparatus for anchoring an intravascular device along a guidewire
CA2523777C (en) 2003-03-14 2016-05-10 Light Sciences Corporation Light generating device to intravascular use
US20050131510A1 (en) * 2003-03-14 2005-06-16 Chen James C. Device for distal protection and treatment of blood vessels
US20070002582A1 (en) * 2003-03-14 2007-01-04 Light Sciences Corporation Medical apparatus employing flexible light structures and methods for manufacturing same
US20080269846A1 (en) * 2003-03-14 2008-10-30 Light Sciences Oncology, Inc. Device for treatment of blood vessels using light
US20080033519A1 (en) * 2003-03-14 2008-02-07 Light Sciences Oncology, Inc. Light generating device for intravascular use
EP1607045A4 (en) 2003-03-27 2011-02-16 Univ Nihon Wire for inserting into biological duct
US20040193208A1 (en) * 2003-03-27 2004-09-30 Scimed Life Systems, Inc. Radiopaque embolic protection filter membrane
US20040199199A1 (en) * 2003-04-02 2004-10-07 Scimed Life Systems, Inc. Filter and method of making a filter
US7604649B2 (en) * 2003-04-29 2009-10-20 Rex Medical, L.P. Distal protection device
US7331976B2 (en) 2003-04-29 2008-02-19 Rex Medical, L.P. Distal protection device
US7780611B2 (en) 2003-05-01 2010-08-24 Boston Scientific Scimed, Inc. Medical instrument with controlled torque transmission
US6969396B2 (en) * 2003-05-07 2005-11-29 Scimed Life Systems, Inc. Filter membrane with increased surface area
US7537600B2 (en) * 2003-06-12 2009-05-26 Boston Scientific Scimed, Inc. Valved embolic protection filter
EP1658011B1 (en) * 2003-07-03 2007-08-15 Cook Incorporated Occluding device for occluding fluid flow through a body vessel
EP1644082A2 (en) * 2003-07-08 2006-04-12 Light Sciences Corporation Light generating device that self centers within a lumen to render photodynamic therapy
US8337519B2 (en) * 2003-07-10 2012-12-25 Boston Scientific Scimed, Inc. Embolic protection filtering device
US9301829B2 (en) 2003-07-30 2016-04-05 Boston Scientific Scimed, Inc. Embolic protection aspirator
US7896898B2 (en) * 2003-07-30 2011-03-01 Boston Scientific Scimed, Inc. Self-centering blood clot filter
US7316692B2 (en) 2003-08-12 2008-01-08 Boston Scientific Scimed, Inc. Laser-cut clot puller
US8393328B2 (en) 2003-08-22 2013-03-12 BiO2 Medical, Inc. Airway assembly and methods of using an airway assembly
US8545418B2 (en) 2004-08-25 2013-10-01 Richard R. Heuser Systems and methods for ablation of occlusions within blood vessels
US20070135907A1 (en) * 2003-10-02 2007-06-14 The Regents Of The University Of California Stent with expandable foam
US20050085826A1 (en) * 2003-10-21 2005-04-21 Scimed Life Systems, Inc. Unfolding balloon catheter for proximal embolus protection
US6994718B2 (en) * 2003-10-29 2006-02-07 Medtronic Vascular, Inc. Distal protection device for filtering and occlusion
US7105064B2 (en) * 2003-11-20 2006-09-12 International Flavors & Fragrances Inc. Particulate fragrance deposition on surfaces and malodour elimination from surfaces
US7716801B2 (en) * 2003-11-24 2010-05-18 Medtronic Vascular, Inc. Low-profile distal protection device
US7651514B2 (en) * 2003-12-11 2010-01-26 Boston Scientific Scimed, Inc. Nose rider improvement for filter exchange and methods of use
EP1691666B1 (en) 2003-12-12 2012-05-30 University of Washington Catheterscope 3d guidance and interface system
WO2005058197A1 (en) * 2003-12-16 2005-06-30 Wholey Mark H Vascular catheter with an expandable section and a distal tip for delivering a thromboembolic protection device and method of use
US7824443B2 (en) 2003-12-23 2010-11-02 Sadra Medical, Inc. Medical implant delivery and deployment tool
US7381219B2 (en) * 2003-12-23 2008-06-03 Sadra Medical, Inc. Low profile heart valve and delivery system
US20050137686A1 (en) * 2003-12-23 2005-06-23 Sadra Medical, A Delaware Corporation Externally expandable heart valve anchor and method
US7329279B2 (en) * 2003-12-23 2008-02-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8579962B2 (en) * 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US7748389B2 (en) * 2003-12-23 2010-07-06 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
EP2529696B1 (en) * 2003-12-23 2014-01-29 Sadra Medical, Inc. Repositionable heart valve
US20050137687A1 (en) * 2003-12-23 2005-06-23 Sadra Medical Heart valve anchor and method
US20050137691A1 (en) * 2003-12-23 2005-06-23 Sadra Medical Two piece heart valve and anchor
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8052749B2 (en) * 2003-12-23 2011-11-08 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US9526609B2 (en) * 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8182528B2 (en) * 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US9005273B2 (en) * 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US20050137694A1 (en) 2003-12-23 2005-06-23 Haug Ulrich R. Methods and apparatus for endovascularly replacing a patient's heart valve
US8603160B2 (en) * 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US7959666B2 (en) 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US7824442B2 (en) * 2003-12-23 2010-11-02 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US7445631B2 (en) 2003-12-23 2008-11-04 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US7763077B2 (en) 2003-12-24 2010-07-27 Biomerix Corporation Repair of spinal annular defects and annulo-nucleoplasty regeneration
US8231649B2 (en) * 2004-01-20 2012-07-31 Boston Scientific Scimed, Inc. Retrievable blood clot filter with retractable anchoring members
US20050165480A1 (en) * 2004-01-23 2005-07-28 Maybelle Jordan Endovascular treatment devices and methods
US20060106447A1 (en) * 2004-01-26 2006-05-18 Nmt Medical, Inc. Adjustable stiffness medical system
US8585771B2 (en) * 2004-02-26 2013-11-19 Endosphere, Inc. Methods and devices to curb appetite and/or to reduce food intake
US9060835B2 (en) * 2006-05-26 2015-06-23 Endosphere, Inc. Conformationally-stabilized intraluminal device for medical applications
US7931693B2 (en) * 2004-02-26 2011-04-26 Endosphere, Inc. Method and apparatus for reducing obesity
US8147561B2 (en) 2004-02-26 2012-04-03 Endosphere, Inc. Methods and devices to curb appetite and/or reduce food intake
US8313505B2 (en) * 2004-03-19 2012-11-20 Aga Medical Corporation Device for occluding vascular defects
US8777974B2 (en) 2004-03-19 2014-07-15 Aga Medical Corporation Multi-layer braided structures for occluding vascular defects
US8398670B2 (en) * 2004-03-19 2013-03-19 Aga Medical Corporation Multi-layer braided structures for occluding vascular defects and for occluding fluid flow through portions of the vasculature of the body
US9039724B2 (en) * 2004-03-19 2015-05-26 Aga Medical Corporation Device for occluding vascular defects
US9707071B2 (en) 2004-11-24 2017-07-18 Contego Medical Llc Percutaneous transluminal angioplasty device with integral embolic filter
US20050234501A1 (en) * 2004-04-15 2005-10-20 Barone David D Braided intraluminal filter
US20050240215A1 (en) * 2004-04-21 2005-10-27 Scimed Life Systems, Inc. Magnetic embolic protection device and method
US8801746B1 (en) 2004-05-04 2014-08-12 Covidien Lp System and method for delivering a left atrial appendage containment device
US7799050B2 (en) * 2004-05-05 2010-09-21 Boston Scientific Scimed, Inc. Devices and methods for magnetically manipulating intravascular devices
US20050251198A1 (en) * 2004-05-06 2005-11-10 Scimed Life Systems, Inc. Intravascular filter membrane and method of forming
US20050267570A1 (en) * 2004-05-27 2005-12-01 Shadduck John H Endovascular occlusion devices and methods of use
US7780725B2 (en) 2004-06-16 2010-08-24 Sadra Medical, Inc. Everting heart valve
US7704267B2 (en) 2004-08-04 2010-04-27 C. R. Bard, Inc. Non-entangling vena cava filter
US7819841B2 (en) * 2004-08-18 2010-10-26 Medtronic Vascular, Inc. Vessel isolation device
US20060047286A1 (en) * 2004-08-31 2006-03-02 Stephen West Clot retrieval device
US8795315B2 (en) * 2004-10-06 2014-08-05 Cook Medical Technologies Llc Emboli capturing device having a coil and method for capturing emboli
US7621904B2 (en) 2004-10-21 2009-11-24 Boston Scientific Scimed, Inc. Catheter with a pre-shaped distal tip
US7794473B2 (en) 2004-11-12 2010-09-14 C.R. Bard, Inc. Filter delivery system
US8771294B2 (en) * 2004-11-26 2014-07-08 Biomerix Corporation Aneurysm treatment devices and methods
US20060116713A1 (en) * 2004-11-26 2006-06-01 Ivan Sepetka Aneurysm treatment devices and methods
US20060149312A1 (en) * 2004-12-30 2006-07-06 Edward Arguello Distal protection device with improved wall apposition
US7295874B2 (en) * 2005-01-06 2007-11-13 Cardiac Pacemakers, Inc. Intermittent stress augmentation pacing for cardioprotective effect
US8252016B2 (en) * 2005-01-13 2012-08-28 Azam Anwar System and method for providing embolic protection
US8480629B2 (en) 2005-01-28 2013-07-09 Boston Scientific Scimed, Inc. Universal utility board for use with medical devices and methods of use
US8267954B2 (en) 2005-02-04 2012-09-18 C. R. Bard, Inc. Vascular filter with sensing capability
US20060184194A1 (en) * 2005-02-15 2006-08-17 Cook Incorporated Embolic protection device
US7993362B2 (en) * 2005-02-16 2011-08-09 Boston Scientific Scimed, Inc. Filter with positioning and retrieval devices and methods
ES2380356T3 (en) * 2005-02-18 2012-05-10 Tyco Healthcare Group Lp Rapid exchange catheter
US20060190024A1 (en) * 2005-02-24 2006-08-24 Bei Nianjiong Recovery catheter apparatus and method
US7530948B2 (en) * 2005-02-28 2009-05-12 University Of Washington Tethered capsule endoscope for Barrett's Esophagus screening
US8945169B2 (en) 2005-03-15 2015-02-03 Cook Medical Technologies Llc Embolic protection device
US8221446B2 (en) 2005-03-15 2012-07-17 Cook Medical Technologies Embolic protection device
US20060224178A1 (en) * 2005-04-05 2006-10-05 Boston Scientific Scimed, Inc. Expandable medical retrieval device and related methods of use
US20060229658A1 (en) * 2005-04-07 2006-10-12 Stivland Timothy M Embolic protection filter with reduced landing zone
US7962208B2 (en) * 2005-04-25 2011-06-14 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US20070055365A1 (en) * 2005-04-28 2007-03-08 The Cleveland Clinic Foundation Stent with integrated filter
US20060259132A1 (en) * 2005-05-02 2006-11-16 Cook Incorporated Vascular stent for embolic protection
WO2006119144A1 (en) * 2005-05-04 2006-11-09 Wilson-Cook Medical Inc. Expandable and retrievable stent
EP1880313A4 (en) 2005-05-12 2015-08-05 Bard Inc C R Removable embolus blood clot filter
US7894896B2 (en) * 2005-05-13 2011-02-22 Cardiac Pacemakers, Inc. Method and apparatus for initiating and delivering cardiac protection pacing
US7917210B2 (en) * 2005-05-13 2011-03-29 Cardiac Pacemakers, Inc. Method and apparatus for cardiac protection pacing
US20060259088A1 (en) * 2005-05-13 2006-11-16 Pastore Joseph M Method and apparatus for delivering pacing pulses using a coronary stent
US8109962B2 (en) 2005-06-20 2012-02-07 Cook Medical Technologies Llc Retrievable device having a reticulation portion with staggered struts
US7850708B2 (en) * 2005-06-20 2010-12-14 Cook Incorporated Embolic protection device having a reticulated body with staggered struts
US20070009564A1 (en) * 2005-06-22 2007-01-11 Mcclain James B Drug/polymer composite materials and methods of making the same
US7766934B2 (en) * 2005-07-12 2010-08-03 Cook Incorporated Embolic protection device with an integral basket and bag
US7771452B2 (en) 2005-07-12 2010-08-10 Cook Incorporated Embolic protection device with a filter bag that disengages from a basket
CA2615452C (en) 2005-07-15 2015-03-31 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
US7818648B2 (en) * 2005-12-18 2010-10-19 Pmc-Sierra Israel Ltd. GPON rogue-ONU detection based on error counts
US20110118773A1 (en) * 2005-07-25 2011-05-19 Rainbow Medical Ltd. Elliptical device for treating afterload
US8187298B2 (en) * 2005-08-04 2012-05-29 Cook Medical Technologies Llc Embolic protection device having inflatable frame
CA2616818C (en) 2005-08-09 2014-08-05 C.R. Bard, Inc. Embolus blood clot filter and delivery system
US7668594B2 (en) 2005-08-19 2010-02-23 Cardiac Pacemakers, Inc. Method and apparatus for delivering chronic and post-ischemia cardiac therapies
US7712606B2 (en) 2005-09-13 2010-05-11 Sadra Medical, Inc. Two-part package for medical implant
US7972359B2 (en) 2005-09-16 2011-07-05 Atritech, Inc. Intracardiac cage and method of delivering same
US8377092B2 (en) 2005-09-16 2013-02-19 Cook Medical Technologies Llc Embolic protection device
US8632562B2 (en) * 2005-10-03 2014-01-21 Cook Medical Technologies Llc Embolic protection device
US8182508B2 (en) 2005-10-04 2012-05-22 Cook Medical Technologies Llc Embolic protection device
US8252017B2 (en) * 2005-10-18 2012-08-28 Cook Medical Technologies Llc Invertible filter for embolic protection
US20070100372A1 (en) * 2005-11-02 2007-05-03 Cook Incorporated Embolic protection device having a filter
US8216269B2 (en) 2005-11-02 2012-07-10 Cook Medical Technologies Llc Embolic protection device having reduced profile
US8287584B2 (en) * 2005-11-14 2012-10-16 Sadra Medical, Inc. Medical implant deployment tool
US8152831B2 (en) * 2005-11-17 2012-04-10 Cook Medical Technologies Llc Foam embolic protection device
US9131999B2 (en) 2005-11-18 2015-09-15 C.R. Bard Inc. Vena cava filter with filament
EP1954193B1 (en) 2005-11-23 2013-03-06 University of Washington Scanning beam with variable sequential framing using interrupted scanning resonance
US8108034B2 (en) 2005-11-28 2012-01-31 Cardiac Pacemakers, Inc. Systems and methods for valvular regurgitation detection
EP1986568B1 (en) * 2006-02-03 2017-04-05 Covidien LP Methods and devices for restoring blood flow within blocked vasculature
US20070185525A1 (en) * 2006-02-07 2007-08-09 White Bradley R Floating on the wire filter wire
EP1988851A2 (en) 2006-02-14 2008-11-12 Sadra Medical, Inc. Systems and methods for delivering a medical implant
WO2007099945A1 (en) 2006-03-02 2007-09-07 Nec Corporation Communication system, mobile terminal, information terminal, communication method, and program
JP2009528128A (en) * 2006-03-03 2009-08-06 ユニヴァーシティ オブ ワシントン Multi clad optical fiber scanner
US20070239198A1 (en) * 2006-04-03 2007-10-11 Boston Scientific Scimed, Inc. Filter and wire with distal isolation
US20070244503A1 (en) * 2006-04-14 2007-10-18 Salviac Limited Method for filtering embolic material
ES2540059T3 (en) 2006-04-26 2015-07-08 Micell Technologies, Inc. Coatings containing multidrug
US20070265655A1 (en) * 2006-05-09 2007-11-15 Boston Scientific Scimed, Inc. Embolic protection filter with enhanced stability within a vessel
US8409238B2 (en) * 2006-05-18 2013-04-02 Boston Scientific Scimed, Inc. Mini cams on support loop for vessel stabilization
DE102006024176B4 (en) 2006-05-23 2008-08-28 Pah, Gunnar M. Device for filtering blood and heart valve stenosis while eliminating a process for removing a heart valve stenosis
WO2007143602A3 (en) 2006-06-05 2008-11-06 Bard Inc C R Embolus blood clot filter utilizable with a single delivery system or a single retrieval system in one of a femoral or jugular access
US20080058629A1 (en) * 2006-08-21 2008-03-06 University Of Washington Optical fiber scope with both non-resonant illumination and resonant collection/imaging for multiple modes of operation
US20080071315A1 (en) * 2006-08-31 2008-03-20 Tamara Colette Baynham Integrated catheter and pulse generator systems and methods
US20100179583A1 (en) * 2006-09-11 2010-07-15 Carpenter Judith T Methods of deploying and retrieving an embolic diversion device
US9339367B2 (en) * 2006-09-11 2016-05-17 Edwards Lifesciences Ag Embolic deflection device
US20100179647A1 (en) * 2006-09-11 2010-07-15 Carpenter Judith T Methods of reducing embolism to cerebral circulation as a consequence of an index cardiac procedure
US8460335B2 (en) 2006-09-11 2013-06-11 Embrella Cardiovascular, Inc. Method of deflecting emboli from the cerebral circulation
US9480548B2 (en) * 2006-09-11 2016-11-01 Edwards Lifesciences Ag Embolic protection device and method of use
US20080071307A1 (en) * 2006-09-19 2008-03-20 Cook Incorporated Apparatus and methods for in situ embolic protection
KR101485141B1 (en) * 2006-10-11 2015-01-22 유로-셀티큐 에스.에이. Light delivery system
JP2008093295A (en) * 2006-10-13 2008-04-24 Keisei Ika Kogyo Kk Capturing body for capturing embolic material
CA2667228C (en) * 2006-10-23 2015-07-14 Micell Technologies, Inc. Holder for electrically charging a substrate during coating
US20080269774A1 (en) * 2006-10-26 2008-10-30 Chestnut Medical Technologies, Inc. Intracorporeal Grasping Device
US20080132834A1 (en) * 2006-12-04 2008-06-05 University Of Washington Flexible endoscope tip bending mechanism using optical fibers as tension members
US8096943B2 (en) * 2006-12-04 2012-01-17 University Of Washington Through Its Center For Commercialization Flexible endoscope tip bending mechanism using optical fiber as compression member
US7879004B2 (en) * 2006-12-13 2011-02-01 University Of Washington Catheter tip displacement mechanism
US20080147110A1 (en) * 2006-12-19 2008-06-19 Lalith Hiran Wijeratne Embolic protection device with distal tubular member for improved torque response
US9737642B2 (en) 2007-01-08 2017-08-22 Micell Technologies, Inc. Stents having biodegradable layers
WO2008086511A3 (en) 2007-01-11 2008-08-28 Ev3 Inc Convertible embolic protection devices and methods of use
US8615296B2 (en) * 2007-03-06 2013-12-24 Cardiac Pacemakers, Inc. Method and apparatus for closed-loop intermittent cardiac stress augmentation pacing
US20080221388A1 (en) * 2007-03-09 2008-09-11 University Of Washington Side viewing optical fiber endoscope
WO2008113857A3 (en) * 2007-03-20 2008-11-27 Minvasys Apparatus and methods for stent delivery with embolic protection
US7686783B2 (en) * 2007-03-30 2010-03-30 Boston Scientific Scimed, Inc. Perfusion and embolic protection
US7780630B2 (en) * 2007-03-30 2010-08-24 Boston Scientific Scimed, Inc. Perfusion device
US20080243170A1 (en) * 2007-03-30 2008-10-02 Boston Scientific Scimed, Inc. Embolic capturing devices and methods
US20080243030A1 (en) * 2007-04-02 2008-10-02 University Of Washington Multifunction cannula tools
US8840566B2 (en) 2007-04-02 2014-09-23 University Of Washington Catheter with imaging capability acts as guidewire for cannula tools
US8535334B2 (en) * 2007-04-17 2013-09-17 Lazarus Effect, Inc. Complex wire formed devices
WO2008137710A1 (en) * 2007-05-03 2008-11-13 University Of Washington High resolution optical coherence tomography based imaging for intraluminal and interstitial use implemented with a reduced form factor
US8128679B2 (en) 2007-05-23 2012-03-06 Abbott Laboratories Vascular Enterprises Limited Flexible stent with torque-absorbing connectors
EP2170418B1 (en) * 2007-05-25 2016-03-16 Micell Technologies, Inc. Polymer films for medical device coating
EP2865404A1 (en) * 2007-06-01 2015-04-29 Covidien LP Extension tubes for balloon catheters
US20110137227A1 (en) * 2007-07-16 2011-06-09 Mckinley James T Methods and devices for delivering or delaying lipids within a duodenum
ES2552821T3 (en) * 2008-07-02 2015-12-02 Endosphere, Inc. Devices for introducing or delay lipids in the duodenum
US9039728B2 (en) 2007-08-31 2015-05-26 BiO2 Medical, Inc. IVC filter catheter with imaging modality
US8613753B2 (en) 2007-08-31 2013-12-24 BiO2 Medical, Inc. Multi-lumen central access vena cava filter apparatus and method of using same
US9687333B2 (en) 2007-08-31 2017-06-27 BiO2 Medical, Inc. Reduced profile central venous access catheter with vena cava filter and method
US8668712B2 (en) * 2007-08-31 2014-03-11 BiO2 Medical, Inc. Multi-lumen central access vena cava filter apparatus and method of using same
US8252018B2 (en) * 2007-09-14 2012-08-28 Cook Medical Technologies Llc Helical embolic protection device
US9138307B2 (en) 2007-09-14 2015-09-22 Cook Medical Technologies Llc Expandable device for treatment of a stricture in a body vessel
US8419748B2 (en) * 2007-09-14 2013-04-16 Cook Medical Technologies Llc Helical thrombus removal device
US20090104371A1 (en) * 2007-09-27 2009-04-23 Fujifilm Corporation Film forming composition, method for producing film, film, and insulating film
US7819844B2 (en) * 2007-10-17 2010-10-26 Gardia Medical Ltd. Guidewire stop
US20090105746A1 (en) * 2007-10-17 2009-04-23 Gardia Medical Ltd Guidewire stop
US8066757B2 (en) * 2007-10-17 2011-11-29 Mindframe, Inc. Blood flow restoration and thrombus management methods
US20090143771A1 (en) * 2007-10-27 2009-06-04 Salviac Limited Filter removal device
US20090112252A1 (en) * 2007-10-27 2009-04-30 Salviac Limited Catheter with removable filter retrieval tip
WO2009053855A3 (en) * 2007-10-27 2009-10-29 Salviac Limited Embolic filter device and method of manufacturing the same
US20090138037A1 (en) * 2007-10-27 2009-05-28 Salviac Limited Strain limiting tether for a catheter
DE102007056946A1 (en) 2007-11-27 2009-05-28 Gunnar Pah Apparatus for filtering blood
US20090137893A1 (en) * 2007-11-27 2009-05-28 University Of Washington Adding imaging capability to distal tips of medical tools, catheters, and conduits
EP2231256A4 (en) * 2007-12-20 2014-05-21 Vortex Medical Systems and methods for removing undesirable material within a circulatory system
US8920488B2 (en) 2007-12-20 2014-12-30 Abbott Laboratories Vascular Enterprises Limited Endoprosthesis having a stable architecture
WO2009086482A1 (en) * 2007-12-26 2009-07-09 Lazarus Effect, Inc. Retrieval systems and methods for use thereof
EP2244668A1 (en) * 2008-01-25 2010-11-03 JenaValve Technology Inc. Medical apparatus for the therapeutic treatment of an insufficient cardiac valve
WO2009097118A1 (en) * 2008-01-29 2009-08-06 Cardiac Pacemakers, Inc Configurable intermittent pacing therapy
US9795708B1 (en) * 2008-01-31 2017-10-24 Iowa State University Research Foundation, Inc. Method for machining metallic foam
US8747453B2 (en) 2008-02-18 2014-06-10 Aga Medical Corporation Stent/stent graft for reinforcement of vascular abnormalities and associated method
US20090208143A1 (en) * 2008-02-19 2009-08-20 University Of Washington Efficient automated urothelial imaging using an endoscope with tip bending
US8940003B2 (en) 2008-02-22 2015-01-27 Covidien Lp Methods and apparatus for flow restoration
US8140155B2 (en) * 2008-03-11 2012-03-20 Cardiac Pacemakers, Inc. Intermittent pacing therapy delivery statistics
US8483826B2 (en) * 2008-03-17 2013-07-09 Cardiac Pacemakers, Inc. Deactivation of intermittent pacing therapy
WO2009146209A1 (en) 2008-04-17 2009-12-03 Micell Technologies, Inc. Stents having bioabsorbable layers
EP2460477A1 (en) 2008-04-21 2012-06-06 NFOCUS Neuromedical, Inc. Braid-ball embolic devices and delivery systems
WO2009150920A1 (en) * 2008-06-09 2009-12-17 株式会社パイオラックスメディカルデバイス Medical treatment tool for tubular organs
US20090318984A1 (en) * 2008-06-19 2009-12-24 Mokelke Eric A External pacemaker with automatic cardioprotective pacing protocol
US8457738B2 (en) * 2008-06-19 2013-06-04 Cardiac Pacemakers, Inc. Pacing catheter for access to multiple vessels
US8639357B2 (en) * 2008-06-19 2014-01-28 Cardiac Pacemakers, Inc. Pacing catheter with stent electrode
US20090318749A1 (en) * 2008-06-19 2009-12-24 Craig Stolen Method and apparatus for pacing and intermittent ischemia
US9409012B2 (en) * 2008-06-19 2016-08-09 Cardiac Pacemakers, Inc. Pacemaker integrated with vascular intervention catheter
WO2009155571A1 (en) * 2008-06-19 2009-12-23 Coherex Medical, Inc. Clot retrieval method and device
US8244352B2 (en) 2008-06-19 2012-08-14 Cardiac Pacemakers, Inc. Pacing catheter releasing conductive liquid
US9037235B2 (en) 2008-06-19 2015-05-19 Cardiac Pacemakers, Inc. Pacing catheter with expandable distal end
US20090318994A1 (en) * 2008-06-19 2009-12-24 Tracee Eidenschink Transvascular balloon catheter with pacing electrodes on shaft
US8206412B2 (en) * 2008-06-23 2012-06-26 Lumen Biomedical, Inc. Embolic protection during percutaneous heart valve replacement and similar procedures
US8052717B2 (en) * 2008-07-14 2011-11-08 Boston Scientific Scimed, Inc. Embolic protection device
EP2313122A4 (en) * 2008-07-17 2013-10-30 Micell Technologies Inc Drug delivery medical device
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
US9179918B2 (en) 2008-07-22 2015-11-10 Covidien Lp Vascular remodeling device
WO2010010545A1 (en) 2008-07-22 2010-01-28 Neuravi Limited Clot capture systems and associated methods
US9402707B2 (en) 2008-07-22 2016-08-02 Neuravi Limited Clot capture systems and associated methods
EP2288300A2 (en) 2008-08-29 2011-03-02 Rapid Medical Ltd. Embolectomy device
US20100056858A1 (en) * 2008-09-02 2010-03-04 Mokelke Eric A Pacing system for use during cardiac catheterization or surgery
US7927350B2 (en) 2008-09-16 2011-04-19 Salviac Limited Plaque liberating device
US8118830B2 (en) * 2008-09-16 2012-02-21 Salviac Limited Method for reducing emboli formation
US8852225B2 (en) * 2008-09-25 2014-10-07 Medtronic, Inc. Emboli guarding device
WO2010038634A1 (en) * 2008-09-30 2010-04-08 テルモ株式会社 Stent delivery system
ES2627860T3 (en) * 2008-10-10 2017-07-31 Boston Scientific Scimed, Inc. to place medical devices medical devices and installation systems
US9795442B2 (en) 2008-11-11 2017-10-24 Shifamed Holdings, Llc Ablation catheters
US9655677B2 (en) 2010-05-12 2017-05-23 Shifamed Holdings, Llc Ablation catheters including a balloon and electrodes
US8295902B2 (en) * 2008-11-11 2012-10-23 Shifamed Holdings, Llc Low profile electrode assembly
US9717557B2 (en) 2008-11-11 2017-08-01 Apama Medical, Inc. Cardiac ablation catheters and methods of use thereof
US9333031B2 (en) 2013-04-08 2016-05-10 Apama Medical, Inc. Visualization inside an expandable medical device
US8444669B2 (en) 2008-12-15 2013-05-21 Boston Scientific Scimed, Inc. Embolic filter delivery system and method
US8388644B2 (en) * 2008-12-29 2013-03-05 Cook Medical Technologies Llc Embolic protection device and method of use
US8372108B2 (en) 2009-01-16 2013-02-12 Claret Medical, Inc. Intravascular blood filter
US9326843B2 (en) 2009-01-16 2016-05-03 Claret Medical, Inc. Intravascular blood filters and methods of use
EP2480165B1 (en) 2009-09-21 2017-08-23 Claret Medical, Inc. Intravascular blood filters
US20100185179A1 (en) * 2009-01-21 2010-07-22 Abbott Cardiovascular Systems Inc. Needled cannula with filter device
US20100191272A1 (en) * 2009-01-23 2010-07-29 Salviac Limited Distal access embolic protection system and methods of using the same
US20100191273A1 (en) * 2009-01-23 2010-07-29 Salviac Limited Embolic protection device with no delivery catheter or retrieval catheter and methods of using the same
US20100191275A1 (en) * 2009-01-27 2010-07-29 Boston Scientific Scimed, Inc. Filter deployment device
WO2010088520A9 (en) * 2009-01-29 2010-12-02 Claret Medical, Inc. Illuminated intravascular blood filter
US20100211094A1 (en) * 2009-02-18 2010-08-19 Cook Incorporated Umbrella distal embolic protection device
JP4510125B1 (en) * 2009-02-20 2010-07-21 株式会社ウィルファイン Thrombus capture device in a blood vessel
EP2403583B1 (en) 2009-03-06 2016-10-19 Lazarus Effect, Inc. Retrieval systems
CA2756388C (en) * 2009-03-23 2015-10-27 Micell Technologies, Inc. Biodegradable polymers with low acidic impurity
CA2759015C (en) 2009-04-17 2017-06-20 James B. Mcclain Stents having controlled elution
US20100274277A1 (en) * 2009-04-27 2010-10-28 Cook Incorporated Embolic protection device with maximized flow-through
WO2010132203A1 (en) 2009-05-15 2010-11-18 Cardiac Pacemakers, Inc. Pacing system with safety control during mode transition
US8958873B2 (en) * 2009-05-28 2015-02-17 Cardiac Pacemakers, Inc. Method and apparatus for safe and efficient delivery of cardiac stress augmentation pacing
WO2010151698A3 (en) * 2009-06-24 2011-03-24 Shifamed, Llc Steerable medical delivery devices and methods of use
CN101612432B (en) 2009-07-06 2012-01-04 成正辉 Transmitting and recycling pipeline of distal protector in blood vessel
US8118817B2 (en) * 2009-07-21 2012-02-21 Cook Medical Technologies Llc Detachable embolization coil
US8753370B2 (en) * 2009-07-27 2014-06-17 Claret Medical, Inc. Dual endovascular filter and methods of use
EP2459119A1 (en) 2009-07-29 2012-06-06 C.R. Bard Inc. Tubular filter
US20110054504A1 (en) * 2009-08-31 2011-03-03 Boston Scientific Scimed, Inc. Recanalization device with expandable cage
US8812104B2 (en) * 2009-09-23 2014-08-19 Cardiac Pacemakers, Inc. Method and apparatus for automated control of pacing post-conditioning
US8412326B2 (en) * 2009-10-30 2013-04-02 Cardiac Pacemakers, Inc. Pacemaker with vagal surge monitoring and response
JP5711251B2 (en) 2009-11-09 2015-04-30 コヴィディエン リミテッド パートナーシップ Braided ball embolic device features
US8696698B2 (en) * 2009-12-02 2014-04-15 Surefire Medical, Inc. Microvalve protection device and method of use for protection against embolization agent reflux
US9539081B2 (en) 2009-12-02 2017-01-10 Surefire Medical, Inc. Method of operating a microvalve protection device
US9770319B2 (en) 2010-12-01 2017-09-26 Surefire Medical, Inc. Closed tip dynamic microvalve protection device
WO2011079285A9 (en) * 2009-12-23 2012-09-27 Pavilion Medical Innovations Reversible vascular filter devices and methods for using same
US8801748B2 (en) 2010-01-22 2014-08-12 Lazarus Effect, Inc. Retrieval systems and methods for use thereof
US8926681B2 (en) 2010-01-28 2015-01-06 Covidien Lp Vascular remodeling device
EP2528542A4 (en) 2010-01-28 2013-07-03 Covidien Lp Vascular remodeling device
US8728067B2 (en) 2010-03-08 2014-05-20 Covidien Lp Microwave antenna probe having a deployable ground plane
US8840601B2 (en) 2010-03-24 2014-09-23 Shifamed Holdings, Llc Intravascular tissue disruption
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
EP2558005A4 (en) * 2010-04-13 2017-08-09 Mivi Neuroscience Llc Embolectomy devices and methods for treatment of acute ischemic stroke condition
CN103118620B (en) 2010-05-12 2015-09-23 施菲姆德控股有限责任公司 Low profile electrode assembly
EP2588042A4 (en) 2010-06-29 2015-03-18 Artventive Medical Group Inc Reducing flow through a tubular structure
US9247942B2 (en) 2010-06-29 2016-02-02 Artventive Medical Group, Inc. Reversible tubal contraceptive device
JP5728779B2 (en) * 2010-07-23 2015-06-03 国立大学法人大阪大学 Intravascular catheter hemostasis
US8538535B2 (en) 2010-08-05 2013-09-17 Rainbow Medical Ltd. Enhancing perfusion by contraction
US9039749B2 (en) 2010-10-01 2015-05-26 Covidien Lp Methods and apparatuses for flow restoration and implanting members in the human body
US20120095500A1 (en) * 2010-10-14 2012-04-19 Heuser Richard R Concentric wire embolism protection device
US9149277B2 (en) 2010-10-18 2015-10-06 Artventive Medical Group, Inc. Expandable device delivery
US9463036B2 (en) 2010-10-22 2016-10-11 Neuravi Limited Clot engagement and removal system
EP2651336A1 (en) * 2010-12-14 2013-10-23 Transcatheter Technologies GmbH Apparatus comprising an aligning device, set and method
CA2822291A1 (en) 2010-12-21 2012-06-28 BiO2 Medical, Inc. Configuration and method for fixation of a filter to a catheter
US9055997B2 (en) 2010-12-30 2015-06-16 Claret Medical, Inc. Method of isolating the cerebral circulation during a cardiac procedure
US8948848B2 (en) 2011-01-07 2015-02-03 Innovative Cardiovascular Solutions, Llc Angiography catheter
EP2672900B1 (en) 2011-02-11 2017-11-01 Covidien LP Two-stage deployment aneurysm embolization devices
US8821478B2 (en) 2011-03-04 2014-09-02 Boston Scientific Scimed, Inc. Catheter with variable stiffness
US9301769B2 (en) 2011-03-09 2016-04-05 Neuravi Limited Clot retrieval device for removing clot from a blood vessel
WO2012127309A4 (en) 2011-03-21 2013-01-31 Montorfano Matteo Disk-based valve apparatus and method for the treatment of valve dysfunction
US9089332B2 (en) 2011-03-25 2015-07-28 Covidien Lp Vascular remodeling device
CA2833387A1 (en) 2011-05-03 2012-11-08 Shifamed Holdings, Llc Steerable delivery sheaths
CA2874586A1 (en) 2011-05-23 2012-11-29 Lazarus Effect, Inc. Retrieval systems and methods for use thereof
JP2014527425A (en) 2011-07-12 2014-10-16 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Coupling system for medical equipment
US9526637B2 (en) 2011-09-09 2016-12-27 Enopace Biomedical Ltd. Wireless endovascular stent-based electrodes
WO2013049448A1 (en) 2011-09-29 2013-04-04 Covidien Lp Vascular remodeling device
US9131926B2 (en) 2011-11-10 2015-09-15 Boston Scientific Scimed, Inc. Direct connect flush system
US8940014B2 (en) 2011-11-15 2015-01-27 Boston Scientific Scimed, Inc. Bond between components of a medical device
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
US9510945B2 (en) 2011-12-20 2016-12-06 Boston Scientific Scimed Inc. Medical device handle
US9277993B2 (en) 2011-12-20 2016-03-08 Boston Scientific Scimed, Inc. Medical device delivery systems
EP2805515A4 (en) 2012-01-17 2015-08-26 Lumen Biomedical Inc Aortic arch filtration system for carotid artery protection
US9089341B2 (en) 2012-02-28 2015-07-28 Surefire Medical, Inc. Renal nerve neuromodulation device
US8961550B2 (en) 2012-04-17 2015-02-24 Indian Wells Medical, Inc. Steerable endoluminal punch
EP2846866A4 (en) * 2012-05-08 2016-04-13 Univ Missouri Embolic protection system
US9308007B2 (en) 2012-08-14 2016-04-12 W. L. Gore & Associates, Inc. Devices and systems for thrombus treatment
CA2880025A1 (en) * 2012-09-12 2014-03-20 Boston Scientific Scimed, Inc. Fixation anchor design for an occlusion device
WO2014066547A1 (en) * 2012-10-23 2014-05-01 Scheinfeld Andrew H Blood loss monitoring and quantification devices, systems, and methods
US9314248B2 (en) 2012-11-06 2016-04-19 Covidien Lp Multi-pivot thrombectomy device
US9295571B2 (en) 2013-01-17 2016-03-29 Covidien Lp Methods and apparatus for luminal stenting
US9095344B2 (en) 2013-02-05 2015-08-04 Artventive Medical Group, Inc. Methods and apparatuses for blood vessel occlusion
US8984733B2 (en) 2013-02-05 2015-03-24 Artventive Medical Group, Inc. Bodily lumen occlusion
US9642635B2 (en) 2013-03-13 2017-05-09 Neuravi Limited Clot removal device
US9463105B2 (en) 2013-03-14 2016-10-11 Covidien Lp Methods and apparatus for luminal stenting
US9433429B2 (en) 2013-03-14 2016-09-06 Neuravi Limited Clot retrieval devices
JP2016513505A (en) 2013-03-14 2016-05-16 ニューラヴィ・リミテッド Clot retrieval device for removing an obstruction clot from a blood vessel
US8715315B1 (en) 2013-03-15 2014-05-06 Insera Therapeutics, Inc. Vascular treatment systems
US8715314B1 (en) 2013-03-15 2014-05-06 Insera Therapeutics, Inc. Vascular treatment measurement methods
US8679150B1 (en) 2013-03-15 2014-03-25 Insera Therapeutics, Inc. Shape-set textile structure based mechanical thrombectomy methods
US9636116B2 (en) 2013-06-14 2017-05-02 Artventive Medical Group, Inc. Implantable luminal devices
US9737308B2 (en) 2013-06-14 2017-08-22 Artventive Medical Group, Inc. Catheter-assisted tumor treatment
US9737306B2 (en) 2013-06-14 2017-08-22 Artventive Medical Group, Inc. Implantable luminal devices
EP3010442B1 (en) * 2013-06-16 2016-12-07 Pi-Cardia Ltd. Percutaneous emboli protection sleeve
US8870948B1 (en) 2013-07-17 2014-10-28 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
US9814477B2 (en) 2013-09-24 2017-11-14 Cook Medical Technologies Llc Clot retrieval system with inverted sleeve
US8900265B1 (en) 2014-01-03 2014-12-02 Legacy Ventures LLC Clot retrieval system
US9155552B2 (en) * 2014-01-03 2015-10-13 Legacy Ventures LLC Clot retrieval system
WO2016056929A1 (en) 2014-10-07 2016-04-14 Balton Sp. Z O.O. Intravascular system for protection of blood vessels
US20160158000A1 (en) 2014-12-09 2016-06-09 Juan F. Granada Replacement cardiac valves and methods of use and manufacture
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
US9566144B2 (en) 2015-04-22 2017-02-14 Claret Medical, Inc. Vascular filters, deflectors, and methods
US9700332B2 (en) 2015-10-23 2017-07-11 Inari Medical, Inc. Intravascular treatment of vascular occlusion and associated devices, systems, and methods
CN106175978A (en) * 2016-08-01 2016-12-07 罗中华 Thrombus guide filter

Citations (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3435824A (en) * 1966-10-27 1969-04-01 Herminio Gamponia Surgical apparatus and related process
US3952747A (en) * 1974-03-28 1976-04-27 Kimmell Jr Garman O Filter and filter insertion instrument
US4423725A (en) * 1982-03-31 1984-01-03 Baran Ostap E Multiple surgical cuff
US4425908A (en) * 1981-10-22 1984-01-17 Beth Israel Hospital Blood clot filter
US4493711A (en) * 1982-06-25 1985-01-15 Thomas J. Fogarty Tubular extrusion catheter
US4512762A (en) * 1982-11-23 1985-04-23 The Beth Israel Hospital Association Method of treatment of atherosclerosis and a balloon catheter for same
US4585000A (en) * 1983-09-28 1986-04-29 Cordis Corporation Expandable device for treating intravascular stenosis
US4643187A (en) * 1983-05-30 1987-02-17 Olympus Optical Co., Ltd. High-frequency incising and excising instrument
US4650466A (en) * 1985-11-01 1987-03-17 Angiobrade Partners Angioplasty device
US4723549A (en) * 1986-09-18 1988-02-09 Wholey Mark H Method and apparatus for dilating blood vessels
US4794928A (en) * 1987-06-10 1989-01-03 Kletschka Harold D Angioplasty device and method of using the same
US4807626A (en) * 1985-02-14 1989-02-28 Mcgirr Douglas B Stone extractor and method
US4817600A (en) * 1987-05-22 1989-04-04 Medi-Tech, Inc. Implantable filter
US4990156A (en) * 1988-06-21 1991-02-05 Lefebvre Jean Marie Filter for medical use
US5011488A (en) * 1988-12-07 1991-04-30 Robert Ginsburg Thrombus extraction system
US5092839A (en) * 1989-09-29 1992-03-03 Kipperman Robert M Coronary thrombectomy
US5100423A (en) * 1990-08-21 1992-03-31 Medical Engineering & Development Institute, Inc. Ablation catheter
US5108419A (en) * 1990-08-16 1992-04-28 Evi Corporation Endovascular filter and method for use thereof
US5178158A (en) * 1990-10-29 1993-01-12 Boston Scientific Corporation Convertible guidewire-catheter with soft tip
US5192284A (en) * 1992-01-10 1993-03-09 Pleatman Mark A Surgical collector and extractor
US5383887A (en) * 1992-12-28 1995-01-24 Celsa Lg Device for selectively forming a temporary blood filter
US5387219A (en) * 1992-09-23 1995-02-07 Target Therapeutics Medical retrieval snare with coil wrapped loop
US5405329A (en) * 1991-01-08 1995-04-11 Durand; Alain J. Intravascular multi-lumen catheter, capable of being implanted by "tunnelling"
US5593394A (en) * 1995-01-24 1997-01-14 Kanesaka; Nozomu Shaft for a catheter system
US5709704A (en) * 1994-11-30 1998-01-20 Boston Scientific Corporation Blood clot filtering
US5720764A (en) * 1994-06-11 1998-02-24 Naderlinger; Eduard Vena cava thrombus filter
US5876367A (en) * 1996-12-05 1999-03-02 Embol-X, Inc. Cerebral protection during carotid endarterectomy and downstream vascular protection during other surgeries
US5882329A (en) * 1997-02-12 1999-03-16 Prolifix Medical, Inc. Apparatus and method for removing stenotic material from stents
US5895410A (en) * 1997-09-12 1999-04-20 B. Braun Medical, Inc. Introducer for an expandable vascular occlusion device
US5895398A (en) * 1996-02-02 1999-04-20 The Regents Of The University Of California Method of using a clot capture coil
US5897567A (en) * 1993-04-29 1999-04-27 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US6010522A (en) * 1996-07-17 2000-01-04 Embol-X, Inc. Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries
US6013093A (en) * 1995-11-28 2000-01-11 Boston Scientific Corporation Blood clot filtering
US6027520A (en) * 1997-05-08 2000-02-22 Embol-X, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
US6048645A (en) * 1997-08-21 2000-04-11 Valence Technology, Inc. Method of preparing lithium ion electrochemical cells
US6051014A (en) * 1998-10-13 2000-04-18 Embol-X, Inc. Percutaneous filtration catheter for valve repair surgery and methods of use
US6053932A (en) * 1997-03-06 2000-04-25 Scimed Life Systems, Inc. Distal protection device
US6168604B1 (en) * 1995-10-06 2001-01-02 Metamorphic Surgical Devices, Llc Guide wire device for removing solid objects from body canals
US6168579B1 (en) * 1999-08-04 2001-01-02 Scimed Life Systems, Inc. Filter flush system and methods of use
US6171327B1 (en) * 1999-02-24 2001-01-09 Scimed Life Systems, Inc. Intravascular filter and method
US6171328B1 (en) * 1999-11-09 2001-01-09 Embol-X, Inc. Intravascular catheter filter with interlocking petal design and methods of use
US6176849B1 (en) * 1999-05-21 2001-01-23 Scimed Life Systems, Inc. Hydrophilic lubricity coating for medical devices comprising a hydrophobic top coat
US6179859B1 (en) * 1999-07-16 2001-01-30 Baff Llc Emboli filtration system and methods of use
US6179861B1 (en) * 1999-07-30 2001-01-30 Incept Llc Vascular device having one or more articulation regions and methods of use
US6203561B1 (en) * 1999-07-30 2001-03-20 Incept Llc Integrated vascular device having thrombectomy element and vascular filter and methods of use
US6206868B1 (en) * 1998-03-13 2001-03-27 Arteria Medical Science, Inc. Protective device and method against embolization during treatment of carotid artery disease
US6214026B1 (en) * 1999-07-30 2001-04-10 Incept Llc Delivery system for a vascular device with articulation region
US20020002384A1 (en) * 1997-11-07 2002-01-03 Paul Gilson Embolic protection device
US6340364B2 (en) * 1999-10-22 2002-01-22 Nozomu Kanesaka Vascular filtering device
US6346116B1 (en) * 1999-08-03 2002-02-12 Medtronic Ave, Inc. Distal protection device
US6348056B1 (en) * 1999-08-06 2002-02-19 Scimed Life Systems, Inc. Medical retrieval device with releasable retrieval basket
US20020022860A1 (en) * 2000-08-18 2002-02-21 Borillo Thomas E. Expandable implant devices for filtering blood flow from atrial appendages
US20020022858A1 (en) * 1999-07-30 2002-02-21 Demond Jackson F. Vascular device for emboli removal having suspension strut and methods of use
US20020026211A1 (en) * 1999-12-23 2002-02-28 Farhad Khosravi Vascular device having emboli and thrombus removal element and methods of use
US6355051B1 (en) * 1999-03-04 2002-03-12 Bioguide Consulting, Inc. Guidewire filter device
US20020032460A1 (en) * 1999-09-21 2002-03-14 Kusleika Richard S. Temporary vascular filter
US6361545B1 (en) * 1997-09-26 2002-03-26 Cardeon Corporation Perfusion filter catheter
US6361546B1 (en) * 2000-01-13 2002-03-26 Endotex Interventional Systems, Inc. Deployable recoverable vascular filter and methods for use
US20030004539A1 (en) * 2001-07-02 2003-01-02 Linder Richard J. Methods, systems, and devices for providing embolic protection and removing embolic material
US20030004541A1 (en) * 2001-07-02 2003-01-02 Rubicon Medical, Inc. Methods, systems, and devices for providing embolic protection
US20030004536A1 (en) * 2001-06-29 2003-01-02 Boylan John F. Variable thickness embolic filtering devices and method of manufacturing the same
US20030004540A1 (en) * 2001-07-02 2003-01-02 Rubicon Medical, Inc. Methods, systems, and devices for deploying an embolic protection filter
US20030004537A1 (en) * 2001-06-29 2003-01-02 Boyle William J. Delivery and recovery sheaths for medical devices
US20030009188A1 (en) * 2001-07-02 2003-01-09 Linder Richard J. Methods, systems, and devices for deploying a filter from a filter device
US6506203B1 (en) * 2000-12-19 2003-01-14 Advanced Cardiovascular Systems, Inc. Low profile sheathless embolic protection system
US6506205B2 (en) * 2001-02-20 2003-01-14 Mark Goldberg Blood clot filtering system
US20030015206A1 (en) * 2001-07-18 2003-01-23 Roth Noah M. Integral vascular filter system
US6511497B1 (en) * 1999-09-14 2003-01-28 Cormedics Gmbh Vascular filter system
US6511503B1 (en) * 1999-12-30 2003-01-28 Advanced Cardiovascular Systems, Inc. Catheter apparatus for treating occluded vessels and filtering embolic debris and method of use
US6511492B1 (en) * 1998-05-01 2003-01-28 Microvention, Inc. Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders
US6511496B1 (en) * 2000-09-12 2003-01-28 Advanced Cardiovascular Systems, Inc. Embolic protection device for use in interventional procedures
US20030023265A1 (en) * 2001-07-13 2003-01-30 Forber Simon John Vascular protection system
US6514273B1 (en) * 2000-03-22 2003-02-04 Endovascular Technologies, Inc. Device for removal of thrombus through physiological adhesion
US6517550B1 (en) * 2000-02-02 2003-02-11 Board Of Regents, The University Of Texas System Foreign body retrieval device
US6517559B1 (en) * 1999-05-03 2003-02-11 O'connell Paul T. Blood filter and method for treating vascular disease
US20030032941A1 (en) * 2001-08-13 2003-02-13 Boyle William J. Convertible delivery systems for medical devices
US20030032977A1 (en) * 1997-11-07 2003-02-13 Salviac Limited Filter element with retractable guidewire tip
US6520978B1 (en) * 2000-05-15 2003-02-18 Intratherapeutics, Inc. Emboli filter
US20030040772A1 (en) * 1999-02-01 2003-02-27 Hideki Hyodoh Delivery devices
US6527746B1 (en) * 2000-08-03 2003-03-04 Ev3, Inc. Back-loading catheter
US20030042186A1 (en) * 2001-08-31 2003-03-06 Boyle William J. Embolic protection devices one way porous membrane
US20030045898A1 (en) * 2001-09-06 2003-03-06 Harrison William J. Embolic protection basket
US6530940B2 (en) * 1999-10-25 2003-03-11 John S. Fisher Emboli capturing device
US6530936B1 (en) * 1998-06-03 2003-03-11 Yeong Seok Yun Apparatus for harvesting cartilage
US6533800B1 (en) * 2001-07-25 2003-03-18 Coaxia, Inc. Devices and methods for preventing distal embolization using flow reversal in arteries having collateral blood flow
US6537295B2 (en) * 2001-03-06 2003-03-25 Scimed Life Systems, Inc. Wire and lock mechanism
US6537296B2 (en) * 1999-04-01 2003-03-25 Scion Cardio-Vascular, Inc. Locking frame, filter and deployment system
US6537294B1 (en) * 2000-10-17 2003-03-25 Advanced Cardiovascular Systems, Inc. Delivery systems for embolic filter devices
US20030060844A1 (en) * 1999-02-12 2003-03-27 Thomas Borillo Vascular filter system
US20030060782A1 (en) * 1998-06-04 2003-03-27 Arani Bose Endovascular thin film devices and methods for treating and preventing stroke
US20030060843A1 (en) * 2001-09-27 2003-03-27 Don Boucher Vascular filter system with encapsulated filter
US20030057156A1 (en) * 2001-03-08 2003-03-27 Dean Peterson Atrial filter implants

Family Cites Families (447)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US123755A (en) * 1872-02-13 Improvement in earth-augers
US615200A (en) 1898-11-29 Automatic weighing-machine
US60782A (en) * 1867-01-01 Geoege h
US225418A (en) * 1880-03-09 Brick-machine
US100917A (en) * 1870-03-15 Improvement in railway rails
US45916A (en) * 1865-01-17 Improvement in smoking-pipes
US123720A (en) * 1872-02-13 Improvement in sawing-machines
US171803A (en) * 1876-01-04 Improvement in parallel rulers
US52626A (en) * 1866-02-13 Improvement in hand-looms
US158574A (en) * 1875-01-12 Improvement in button-hole-cutting attachments for sewing-machines
US532942A (en) * 1895-01-22 Charles bivort and jean nadlee
US173815A (en) * 1876-02-22 Improvement in billiard-table chalk-holders
US187475A (en) * 1877-02-20 Improvement in egg-testers
US173817A (en) * 1876-02-22 Improvement in reapers
US45898A (en) * 1865-01-10 Improvement in rifling breech-loading fire-arms
US199819A (en) * 1878-01-29 Improvement in methods of compressing air
US171770A (en) * 1876-01-04 Improvement in machines for setting eyelets
US60844A (en) * 1867-01-01 William a
US62135A (en) * 1867-02-19 Improvement in gaps foe coffin soeews
US135162A (en) * 1873-01-21 Improvement in excavators
US187495A (en) * 1877-02-20 Improvement in wrappers for bonbons
US100918A (en) * 1870-03-15 Improved ice-cream freezer
US22858A (en) * 1859-02-08 Washing-machine
US146404A (en) * 1874-01-13 Improvement in combined plows, scrapers, and choppers
US7947A (en) * 1851-02-25 Bellows fob musical instruments
US60843A (en) * 1867-01-01 Juan s
US171771A (en) * 1876-01-04 Improvement in corn-planters
US188314A (en) * 1877-03-13 Improvement in pulley-blocks
US212361A (en) * 1879-02-18 Improvement in curbs or hoops for millstones
US212431A (en) * 1879-02-18 Improvement in fasteners for meeting-rails of sashes
US187474A (en) * 1877-02-20 Improvement in
US62133A (en) * 1867-02-19 Improved ice-watee eeoeptaole
US161395A (en) * 1875-03-30 Improvement in harvesters
US161393A (en) * 1875-03-30 Improvement in dental pluggers
US45918A (en) * 1865-01-17 Improved mode of ventilating mines
US161392A (en) * 1875-03-30 Improvement in protractors
US41908A (en) * 1864-03-15 Improvement in saw-mills
US212429A (en) * 1879-02-18 Improvement in plow attachments
US52638A (en) * 1866-02-13 Improvement in saw-sets
US99407A (en) * 1870-02-01 Improvement in oil-can s
US22860A (en) * 1859-02-08 Improvement in cultivators
US111649A (en) * 1871-02-07 Improvement in bit-braces
US161390A (en) * 1875-03-30 Allan cummings
US135232A (en) * 1873-01-28 Improvement in tan-vats
US212434A (en) * 1879-02-18 Improvement in dental pluggers
US111648A (en) * 1871-02-07 Improvement in augers
US23265A (en) * 1859-03-15 Steering- apparatus
US2033733A (en) * 1934-05-26 1936-03-10 Myard Francis Emile Homokinetic transmission joint
US2592546A (en) * 1945-07-16 1952-04-15 Dirkman Agnes Marie Photoengraving
US2943626A (en) 1957-01-31 1960-07-05 Dormia Enrico Instruments for the extraction of foreign bodies
US2854983A (en) 1957-10-31 1958-10-07 Arnold M Baskin Inflatable catheter
US3334629A (en) 1964-11-09 1967-08-08 Bertram D Cohn Occlusive device for inferior vena cava
US3510431A (en) * 1967-08-24 1970-05-05 Sinclair Research Inc High temperature synthetic ester base lubricant composition blends with liquid diesters of dihydroxy biphenyls
US3540431A (en) 1968-04-04 1970-11-17 Kazi Mobin Uddin Collapsible filter for fluid flowing in closed passageway
US3692029A (en) 1971-05-03 1972-09-19 Edwin Lloyd Adair Retention catheter and suprapubic shunt
US3730185A (en) 1971-10-29 1973-05-01 Cook Inc Endarterectomy apparatus
DE2364571A1 (en) * 1973-12-24 1975-09-04 Gustav Ickes Wall element for use preferably as a supporting outer wall portion
DE2821048C2 (en) 1978-05-13 1980-07-17 Willy Ruesch Gmbh & Co Kg, 7053 Kernen
DE2940665A1 (en) * 1978-10-16 1980-04-24 Plg Res A process for producing a network with rautenfoermigen mesh network as well as with mesh-rautenfoermigen
US4295464A (en) 1980-03-21 1981-10-20 Shihata Alfred A Ureteric stone extractor with two ballooned catheters
US4395464A (en) * 1981-04-01 1983-07-26 Marko Materials, Inc. Copper base alloys made using rapidly solidified powders and method
US4404971A (en) 1981-04-03 1983-09-20 Leveen Harry H Dual balloon catheter
DE3235974A1 (en) 1981-11-24 1983-06-01 Weikl Andreas An apparatus for removing or for expanding constrictions in blood vessels leading body fluid
US4425909A (en) 1982-01-04 1984-01-17 Rieser Michael J Laryngoscope
US5053088A (en) 1982-05-05 1991-10-01 The United States Of America As Represented By The Secretary Of The Army Heat-expandable beads as burning rate accelerators
US4445892A (en) 1982-05-06 1984-05-01 Laserscope, Inc. Dual balloon catheter device
US4643184A (en) 1982-09-29 1987-02-17 Mobin Uddin Kazi Embolus trap
JPH0447058B2 (en) 1984-01-20 1992-07-31 Tsudakoma Ind Co Ltd
US4586919A (en) 1984-04-06 1986-05-06 Taheri Syde A External shunt and method for procuring and preserving the endothelium of a vein used in arterial bypass
US4611594A (en) 1984-04-11 1986-09-16 Northwestern University Medical instrument for containment and removal of calculi
DK151404C (en) 1984-05-23 1988-07-18 Cook Europ Aps William Collapsible filter for implantation in a patient's blood vessel
US4926858A (en) 1984-05-30 1990-05-22 Devices For Vascular Intervention, Inc. Atherectomy device for severe occlusions
FR2580504B1 (en) 1985-04-22 1987-07-10 Pieronne Alain Filter for the partial and at least temporary interruption of a vein catheter and the filter carrier
US4790812A (en) 1985-11-15 1988-12-13 Hawkins Jr Irvin F Apparatus and method for removing a target object from a body passsageway
US4810874A (en) * 1985-12-27 1989-03-07 Fuji Photo Film Co., Ltd. Radiation image read-out apparatus and cassette used for the same
EP0256683A3 (en) 1986-08-04 1989-08-09 Aries Medical Incorporated Means for furling a balloon of a balloon catheter
US4712551A (en) 1986-10-14 1987-12-15 Rayhanabad Simon B Vascular shunt
FR2606641B1 (en) 1986-11-17 1991-07-12 Promed filtering device for blood clots
GB2200848B (en) 1987-02-25 1991-02-13 Mo Med Inst Pirogova Intravenous filter, and apparatus and method for preoperative preparation thereof
FR2616666A1 (en) 1987-06-22 1988-12-23 Scit Sc Device of the catheter type for extracting and repositioning filters of the Greenfield or similar type which are wrongly positioned, through the vein
US4867156A (en) 1987-06-25 1989-09-19 Stack Richard S Percutaneous axial atheroectomy catheter assembly and method of using the same
DE3737109A1 (en) * 1987-11-02 1989-05-11 Jacobs Suchard Gmbh A process for preserving raw coffee extract
US4873978A (en) 1987-12-04 1989-10-17 Robert Ginsburg Device and method for emboli retrieval
FR2624747A1 (en) * 1987-12-18 1989-06-23 Delsanti Gerard removable endo-arterial devices intended to repairing detachments walls of the arteries
FR2632864B2 (en) 1987-12-31 1990-10-19 Biomat Sarl filtering system for anti-embolic elastic vena cava and all means for its implementation
US4886061A (en) 1988-02-09 1989-12-12 Medinnovations, Inc. Expandable pullback atherectomy catheter system
US4998933A (en) * 1988-06-10 1991-03-12 Advanced Angioplasty Products, Inc. Thermal angioplasty catheter and method
US4832055A (en) 1988-07-08 1989-05-23 Palestrant Aubrey M Mechanically locking blood clot filter
US5254622A (en) 1988-12-09 1993-10-19 Asahi Kasei Kogyo Kabushiki Kaisha ABS resin compositions and molded articles thereof having improved coating performances
US4927426A (en) 1989-01-03 1990-05-22 Dretler Stephen P Catheter device
US5152777A (en) 1989-01-25 1992-10-06 Uresil Corporation Device and method for providing protection from emboli and preventing occulsion of blood vessels
US5183887A (en) * 1989-02-02 1993-02-02 Merck & Co., Inc. Spirocyclic 6-amido-carbapenems and azetidinones
US4969891A (en) 1989-03-06 1990-11-13 Gewertz Bruce L Removable vascular filter
EP0408245B1 (en) 1989-07-13 1994-03-02 American Medical Systems, Inc. Stent placement instrument
US5002560A (en) * 1989-09-08 1991-03-26 Advanced Cardiovascular Systems, Inc. Expandable cage catheter with a rotatable guide
GB2238485B (en) 1989-11-28 1993-07-14 Cook William Europ A collapsible filter for introduction in a blood vessel of a patient
US5421832A (en) 1989-12-13 1995-06-06 Lefebvre; Jean-Marie Filter-catheter and method of manufacturing same
US5122125A (en) 1990-04-25 1992-06-16 Ashridge A.G. Catheter for angioplasty with soft centering tip
US5171233A (en) 1990-04-25 1992-12-15 Microvena Corporation Snare-type probe
CA2038605C (en) 1990-06-15 2000-06-27 Leonard Pinchuk Crack-resistant polycarbonate urethane polymer prostheses and the like
CA2048307C (en) 1990-08-14 1998-08-18 Rolf Gunther Method and apparatus for filtering blood in a blood vessel of a patient
DE69124395T2 (en) * 1990-11-09 1997-08-28 Boston Scient Corp Guidewire for crossing occlusions in blood vessels
US5053008A (en) 1990-11-21 1991-10-01 Sandeep Bajaj Intracardiac catheter
US5454788A (en) 1991-04-24 1995-10-03 Baxter International Inc. Exchangeable integrated-wire balloon catheter
DE9109006U1 (en) 1991-07-22 1991-10-10 Schmitz-Rode, Thomas, Dipl.-Ing. Dr.Med., 5100 Aachen, De
CA2091686C (en) 1991-08-19 1997-09-30 Nikolai Borisovich Leonidov Crystalline modification of 2-dimethylaminoethyl-n-butylaminobenzoate hydrochloride, method for production thereof and pharmaceutical preparation for anesthesia of eyes, based thereon
EP0529902B1 (en) * 1991-08-21 1999-02-10 SMITH & NEPHEW, INC. Fluid management system
US5626605A (en) 1991-12-30 1997-05-06 Scimed Life Systems, Inc. Thrombosis filter
FR2689388B1 (en) 1992-04-07 1999-07-16 Celsa Lg blood filter perfects possibly resorbable.
CA2118886C (en) 1993-05-07 1998-12-08 Dennis Vigil Method and apparatus for dilatation of a stenotic vessel
US5324304A (en) 1992-06-18 1994-06-28 William Cook Europe A/S Introduction catheter set for a collapsible self-expandable implant
CA2085543A1 (en) 1992-11-03 1994-05-04 Robert E. Fischell Radiopaque non-kinking thin-walled introducer sheath
US5329947A (en) * 1992-11-05 1994-07-19 Auto-Shade, Inc. Cosmetic bag for hanging on the sun visor of an automobile
US5490859A (en) * 1992-11-13 1996-02-13 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5540707A (en) 1992-11-13 1996-07-30 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5792157A (en) * 1992-11-13 1998-08-11 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
CA2161640C (en) 1993-04-29 2005-04-12 Thomas V. Ressemann Expandable intravascular occlusion material removal device
US5354310A (en) 1993-03-22 1994-10-11 Cordis Corporation Expandable temporary graft
US5843167A (en) 1993-04-22 1998-12-01 C. R. Bard, Inc. Method and apparatus for recapture of hooked endoprosthesis
JPH07124251A (en) 1993-06-27 1995-05-16 Terumo Corp Blood filter for indwelling in artery
DE4321575C1 (en) 1993-06-30 1994-11-17 Rasmussen Gmbh Corrugated pipe of thermoplastic material
DE69433064T2 (en) 1993-10-01 2004-06-17 Boston Scientific Corp., Natick Vena cava filter
FR2713081B1 (en) 1993-11-29 1996-01-12 Celsa Lg improved blood filter two sets of legs petals.
US5407354A (en) * 1993-12-03 1995-04-18 Gull Laboratories, Inc. Anti-microbial apparatus and method for dental handpieces
US5441516A (en) * 1994-03-03 1995-08-15 Scimed Lifesystems Inc. Temporary stent
WO1995032454A1 (en) 1994-05-19 1995-11-30 Hoechst Celanese Corporation Single coating transfer color proofing system
US5683451A (en) 1994-06-08 1997-11-04 Cardiovascular Concepts, Inc. Apparatus and methods for deployment release of intraluminal prostheses
GB2290236B (en) 1994-06-16 1998-08-05 Roger Harrington Fox Vena-cava filter
US6123715A (en) 1994-07-08 2000-09-26 Amplatz; Curtis Method of forming medical devices; intravascular occlusion devices
JPH10504738A (en) 1994-07-08 1998-05-12 マイクロベナ コーポレイション Forming method and vascular embolization device of the medical device
US5497995A (en) * 1994-07-29 1996-03-12 Swisshelm; Charles T. Metalwood with raised sole
US5545210A (en) * 1994-09-22 1996-08-13 Advanced Coronary Technology, Inc. Method of implanting a permanent shape memory alloy stent
US5658296A (en) 1994-11-21 1997-08-19 Boston Scientific Corporation Method for making surgical retrieval baskets
US5549626A (en) 1994-12-23 1996-08-27 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Vena caval filter
DE19513164A1 (en) 1995-04-07 1996-10-10 Bayer Ag Hydroxy-terminated polycarbonates based on high mol. cyclic dimer diols with and use in prodn. of polyurethanes stable against hydrolysis and oxidn.
US5795322A (en) 1995-04-10 1998-08-18 Cordis Corporation Catheter with filter and thrombus-discharge device
US5707354A (en) 1995-04-17 1998-01-13 Cardiovascular Imaging Systems, Inc. Compliant catheter lumen and methods
NL1001410C2 (en) 1995-05-19 1996-11-20 Cordis Europ Medical device for long-term stay in a body.
US5681347A (en) * 1995-05-23 1997-10-28 Boston Scientific Corporation Vena cava filter delivery system
US6544276B1 (en) 1996-05-20 2003-04-08 Medtronic Ave. Inc. Exchange method for emboli containment
US5788707A (en) 1995-06-07 1998-08-04 Scimed Life Systems, Inc. Pull back sleeve system with compression resistant inner shaft
JPH0922385A (en) * 1995-07-05 1997-01-21 Rohm Co Ltd Data security device and method
US5762631A (en) 1995-07-14 1998-06-09 Localmed, Inc. Method and system for reduced friction introduction of coaxial catheters
US5766203A (en) 1995-07-20 1998-06-16 Intelliwire, Inc. Sheath with expandable distal extremity and balloon catheters and stents for use therewith and method
CA2227976A1 (en) * 1995-08-03 1997-02-20 Toshiharu Yamabayashi Fluororesin sheet, process for producing the same, and the use of same
FR2737653B1 (en) 1995-08-10 1997-09-19 Braun Celsa Sa definitive filter having an orifice for the passage of medical instruments and process for its manufacturing
JP3656680B2 (en) * 1995-09-21 2005-06-08 株式会社リコー Reversible heat sensitive color developing composition, and reversible recording medium using the same
US6264663B1 (en) 1995-10-06 2001-07-24 Metamorphic Surgical Devices, Llc Device for removing solid objects from body canals, cavities and organs including an invertable basket
WO2001072205A3 (en) 1998-01-26 2002-01-03 Metamorphic Surgical Devices L Method and apparatus for capturing objects beyond an operative site in medical procedures
US5779716A (en) 1995-10-06 1998-07-14 Metamorphic Surgical Devices, Inc. Device for removing solid objects from body canals, cavities and organs
US5769816A (en) 1995-11-07 1998-06-23 Embol-X, Inc. Cannula with associated filter
BE1009746A3 (en) 1995-11-07 1997-07-01 Dereume Jean Pierre Georges Em Capture device introduced in a cavity of a human or animal body.
US5989281A (en) 1995-11-07 1999-11-23 Embol-X, Inc. Cannula with associated filter and methods of use during cardiac surgery
WO1997017914A1 (en) 1995-11-13 1997-05-22 Scimed Life Systems, Inc. Stent retrieval device
US5769871A (en) 1995-11-17 1998-06-23 Louisville Laboratories, Inc. Embolectomy catheter
US5695519A (en) 1995-11-30 1997-12-09 American Biomed, Inc. Percutaneous filter for carotid angioplasty
NL1002423C2 (en) 1996-02-22 1997-08-25 Cordis Europ Temporary filter catheter.
US5665103A (en) * 1996-03-07 1997-09-09 Scimed Life Systems, Inc. Stent locating device
US6096053A (en) 1996-05-03 2000-08-01 Scimed Life Systems, Inc. Medical retrieval basket
US5935139A (en) 1996-05-03 1999-08-10 Boston Scientific Corporation System for immobilizing or manipulating an object in a tract
WO1997042879A1 (en) 1996-05-14 1997-11-20 Embol-X, Inc. Aortic occluder with associated filter and methods of use during cardiac surgery
US6270477B1 (en) 1996-05-20 2001-08-07 Percusurge, Inc. Catheter for emboli containment
US5834449A (en) 1996-06-13 1998-11-10 The Research Foundation Of State University Of New York Treatment of aortic and vascular aneurysms with tetracycline compounds
NL1003497C2 (en) 1996-07-03 1998-01-07 Cordis Europ Catheter with a temporary vena cava filter.
US5669933A (en) 1996-07-17 1997-09-23 Nitinol Medical Technologies, Inc. Removable embolus blood clot filter
US6007543A (en) * 1996-08-23 1999-12-28 Scimed Life Systems, Inc. Stent delivery system with stent securement means
NL1003984C2 (en) 1996-09-09 1998-03-10 Cordis Europ Catheter with internal verstijvingsbruggen.
US5725519A (en) 1996-09-30 1998-03-10 Medtronic Instent Israel Ltd. Stent loading device for a balloon catheter
US6027509A (en) 1996-10-03 2000-02-22 Scimed Life Systems, Inc. Stent retrieval device
US6395017B1 (en) 1996-11-15 2002-05-28 C. R. Bard, Inc. Endoprosthesis delivery catheter with sequential stage control
US6447530B1 (en) 1996-11-27 2002-09-10 Scimed Life Systems, Inc. Atraumatic anchoring and disengagement mechanism for permanent implant device
FR2758078B1 (en) 1997-01-03 1999-07-16 Braun Celsa Sa Blood filter permeability IMPROVED
US5817071A (en) 1997-01-09 1998-10-06 Medtronic, Inc. Oval-shaped cardiac cannula
US6391044B1 (en) 1997-02-03 2002-05-21 Angioguard, Inc. Vascular filter system
US6991641B2 (en) 1999-02-12 2006-01-31 Cordis Corporation Low profile vascular filter system
DE69830340D1 (en) 1997-02-03 2005-06-30 Angioguard Inc vascular filters
US20020169458A1 (en) 1997-02-06 2002-11-14 Connors John J. ICA angioplasty with cerebral protection
US6295989B1 (en) 1997-02-06 2001-10-02 Arteria Medical Science, Inc. ICA angioplasty with cerebral protection
CA2280117A1 (en) 1997-02-12 1998-08-13 Prolifix Medical, Inc. Apparatus for removal of material from stents
US5800457A (en) 1997-03-05 1998-09-01 Gelbfish; Gary A. Intravascular filter and associated methodology
US6652480B1 (en) 1997-03-06 2003-11-25 Medtronic Ave., Inc. Methods for reducing distal embolization
US6726703B2 (en) 2000-11-27 2004-04-27 Scimed Life Systems, Inc. Distal protection device and method
US5827324A (en) 1997-03-06 1998-10-27 Scimed Life Systems, Inc. Distal protection device
US6974469B2 (en) 1997-03-06 2005-12-13 Scimed Life Systems, Inc. Distal protection device and method
WO1998039053A1 (en) * 1997-03-06 1998-09-11 Scimed Life Systems, Inc. Distal protection device and method
US5897564A (en) * 1997-04-08 1999-04-27 Ethicon Endo-Surgery, Inc. Endoscopic instrument assembly for fastening tissue
EP1011532B1 (en) 1997-04-23 2014-05-07 Ethicon Endo-Surgery, Inc. Bifurcated stent and distal protection system
US5879697A (en) 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
US5846260A (en) 1997-05-08 1998-12-08 Embol-X, Inc. Cannula with a modular filter for filtering embolic material
US6676682B1 (en) 1997-05-08 2004-01-13 Scimed Life Systems, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
DE69834723T2 (en) 1997-05-16 2007-05-03 Embolic Protection, Inc., , Campbell Catheter and filter assembly with a pressure equalized seal
US5954745A (en) 1997-05-16 1999-09-21 Gertler; Jonathan Catheter-filter set having a compliant seal
US6059814A (en) * 1997-06-02 2000-05-09 Medtronic Ave., Inc. Filter for filtering fluid in a bodily passageway
US5800525A (en) 1997-06-04 1998-09-01 Vascular Science, Inc. Blood filter
US5848964A (en) 1997-06-06 1998-12-15 Samuels; Shaun Lawrence Wilkie Temporary inflatable filter device and method of use
US5947995A (en) 1997-06-06 1999-09-07 Samuels; Shaun Lawrence Wilkie Method and apparatus for removing blood clots and other objects
US6245088B1 (en) 1997-07-07 2001-06-12 Samuel R. Lowery Retrievable umbrella sieve and method of use
US5928260A (en) 1997-07-10 1999-07-27 Scimed Life Systems, Inc. Removable occlusion system for aneurysm neck
US6086577A (en) 1997-08-13 2000-07-11 Scimed Life Systems, Inc. Detachable aneurysm neck bridge (III)
US5911725A (en) 1997-08-22 1999-06-15 Boury; Harb N. Intraluminal retrieval catheter
US5941896A (en) 1997-09-08 1999-08-24 Montefiore Hospital And Medical Center Filter and method for trapping emboli during endovascular procedures
DE19740036C1 (en) * 1997-09-11 1998-11-12 Hrch Huppmann Gmbh Process and assembly to purge brewing barley mill of air
FR2768326B1 (en) 1997-09-18 1999-10-22 De Bearn Olivier Despalle Temporary blood filter
US6395014B1 (en) 1997-09-26 2002-05-28 John A. Macoviak Cerebral embolic protection assembly and associated methods
JPH11100112A (en) 1997-09-27 1999-04-13 Ricoh Co Ltd Belt device
US6066149A (en) 1997-09-30 2000-05-23 Target Therapeutics, Inc. Mechanical clot treatment device with distal filter
US6099534A (en) * 1997-10-01 2000-08-08 Scimed Life Systems, Inc. Releasable basket
US5908435A (en) 1997-10-23 1999-06-01 Samuels; Shaun L. W. Expandable lumen device and method of use
US6461370B1 (en) 1998-11-03 2002-10-08 C. R. Bard, Inc. Temporary vascular filter guide wire
EP1028671B1 (en) 1997-11-03 2005-01-12 C.R. Bard Inc. Temporary vascular filter guide wire
DE69839888D1 (en) 1997-11-12 2008-09-25 Genesis Technologies Llc A device for removing occlusions in biological passages
NL1007584C2 (en) 1997-11-19 1999-05-20 Cordis Europ Vena cava filter.
US6254563B1 (en) 1997-12-15 2001-07-03 Cardeon Corporation Perfusion shunt apparatus and method
US6258120B1 (en) 1997-12-23 2001-07-10 Embol-X, Inc. Implantable cerebral protection device and methods of use
EP0939142A1 (en) 1998-02-27 1999-09-01 Ticona GmbH Thermal spray powder incorporating an oxidised polyarylene sulfide
EP1061856A1 (en) 1998-03-04 2000-12-27 Bioguide Consulting, Inc. Guidewire filter device
US6152946A (en) 1998-03-05 2000-11-28 Scimed Life Systems, Inc. Distal protection device and method
WO2000076390A3 (en) 1999-06-14 2002-01-17 Arteria Medical Science Inc Methods and low profile apparatus for reducing embolization during treatment of carotid artery disease
US6423032B2 (en) 1998-03-13 2002-07-23 Arteria Medical Science, Inc. Apparatus and methods for reducing embolization during treatment of carotid artery disease
US6632236B2 (en) 1999-03-12 2003-10-14 Arteria Medical Science, Inc. Catheter having radially expandable main body
US6908474B2 (en) 1998-05-13 2005-06-21 Gore Enterprise Holdings, Inc. Apparatus and methods for reducing embolization during treatment of carotid artery disease
US6893450B2 (en) 1999-03-26 2005-05-17 Cook Urological Incorporated Minimally-invasive medical retrieval device
CA2323655A1 (en) 1998-04-02 1999-10-14 Salviac Limited Delivery catheter
DE69929182T2 (en) 1998-04-23 2006-09-21 Boston Scientific Ltd., St. Michael A medical device for recovery of the separated parts of organs by means of slings
US6450989B2 (en) 1998-04-27 2002-09-17 Artemis Medical, Inc. Dilating and support apparatus with disease inhibitors and methods for use
US6007557A (en) 1998-04-29 1999-12-28 Embol-X, Inc. Adjustable blood filtration system
US5984947A (en) 1998-05-04 1999-11-16 Scimed Life Systems, Inc. Removable thrombus filter
US6132458A (en) 1998-05-15 2000-10-17 American Medical Systems, Inc. Method and device for loading a stent
EP1087724A1 (en) 1998-06-16 2001-04-04 Mind-Guard Ltd. Implantable blood filtering device
US6241746B1 (en) 1998-06-29 2001-06-05 Cordis Corporation Vascular filter convertible to a stent and method
US5928261A (en) 1998-06-29 1999-07-27 Ruiz; Carlos E. Removable vascular filter, catheter system and methods of use
NL1009551C2 (en) 1998-07-03 2000-01-07 Cordis Europ Vena cava filter improvements for controlled ejection.
US6306163B1 (en) 1998-08-04 2001-10-23 Advanced Cardiovascular Systems, Inc. Assembly for collecting emboli and method of use
US6547760B1 (en) 1998-08-06 2003-04-15 Cardeon Corporation Aortic catheter with porous aortic arch balloon and methods for selective aortic perfusion
US6093173A (en) 1998-09-09 2000-07-25 Embol-X, Inc. Introducer/dilator with balloon protection and methods of use
US6342062B1 (en) 1998-09-24 2002-01-29 Scimed Life Systems, Inc. Retrieval devices for vena cava filter
US6096027A (en) 1998-09-30 2000-08-01 Impra, Inc., A Subsidiary Of C.R. Bard, Inc. Bag enclosed stent loading apparatus
US7044134B2 (en) 1999-11-08 2006-05-16 Ev3 Sunnyvale, Inc Method of implanting a device in the left atrial appendage
US6083239A (en) 1998-11-24 2000-07-04 Embol-X, Inc. Compliant framework and methods of use
US6652554B1 (en) 1999-01-04 2003-11-25 Mark H. Wholey Instrument for thromboembolic protection
US6371935B1 (en) 1999-01-22 2002-04-16 Cardeon Corporation Aortic catheter with flow divider and methods for preventing cerebral embolization
WO2000044428A8 (en) 1999-01-28 2000-11-02 Adam Spence Europ Ltd Catheter with an expandable end portion
EP1027868A1 (en) * 1999-02-09 2000-08-16 Paul A. Dr. med. Müller Traction device for the adjustment of an upper jaw
US20020169474A1 (en) 1999-03-08 2002-11-14 Microvena Corporation Minimally invasive medical device deployment and retrieval system
US6245012B1 (en) 1999-03-19 2001-06-12 Nmt Medical, Inc. Free standing filter
US6231589B1 (en) 1999-03-22 2001-05-15 Microvena Corporation Body vessel filter
US6277139B1 (en) 1999-04-01 2001-08-21 Scion Cardio-Vascular, Inc. Vascular protection and embolic material retriever
US7150756B2 (en) 1999-04-01 2006-12-19 Scion Cardio-Vascular, Inc Radiopaque locking frame, filter and flexible end
US7014647B2 (en) 1999-05-07 2006-03-21 Salviac Limited Support frame for an embolic protection device
US6918921B2 (en) 1999-05-07 2005-07-19 Salviac Limited Support frame for an embolic protection device
WO2000067829A1 (en) 1999-05-07 2000-11-16 Salviac Limited Improvements in medical guidewires
WO2000067667A1 (en) 1999-05-07 2000-11-16 Salviac Limited A filter element with retractable guidewire tip
JP2002543877A (en) 1999-05-07 2002-12-24 サルヴィアック・リミテッド The embolic protection device
US6964672B2 (en) 1999-05-07 2005-11-15 Salviac Limited Support frame for an embolic protection device
WO2000067664A1 (en) 1999-05-07 2000-11-16 Salviac Limited An embolic protection device
US20020058911A1 (en) * 1999-05-07 2002-05-16 Paul Gilson Support frame for an embolic protection device
WO2000067665A1 (en) 1999-05-07 2000-11-16 Salviac Limited Support frame for embolic protection device
WO2000067666A1 (en) 1999-05-07 2000-11-16 Salviac Limited Improved filter element for embolic protection device
US6585756B1 (en) 1999-05-14 2003-07-01 Ernst P. Strecker Implantable lumen prosthesis
US6068645A (en) 1999-06-07 2000-05-30 Tu; Hosheng Filter system and methods for removing blood clots and biological material
US6458139B1 (en) 1999-06-21 2002-10-01 Endovascular Technologies, Inc. Filter/emboli extractor for use in variable sized blood vessels
US7500956B1 (en) 1999-06-29 2009-03-10 Wilk Peter J Apparatus and method for resonant destruction of tumors
US6471655B1 (en) 1999-06-29 2002-10-29 Vitalwave Corporation Method and apparatus for the noninvasive determination of arterial blood pressure
US20030150821A1 (en) 1999-07-16 2003-08-14 Bates Mark C. Emboli filtration system and methods of use
US6468291B2 (en) 1999-07-16 2002-10-22 Baff Llc Emboli filtration system having integral strut arrangement and methods of use
WO2001008742A9 (en) 1999-07-30 2002-09-06 Incept Llc Vascular filter having articulation region and methods of use in the ascending aorta
US6530939B1 (en) 1999-07-30 2003-03-11 Incept, Llc Vascular device having articulation region and methods of use
US7229463B2 (en) 1999-07-30 2007-06-12 Angioguard, Inc. Vascular filter system for cardiopulmonary bypass
US6371970B1 (en) 1999-07-30 2002-04-16 Incept Llc Vascular filter having articulation region and methods of use in the ascending aorta
WO2001008743A1 (en) 1999-07-30 2001-02-08 Incept Llc Vascular device for emboli, thrombus and foreign body removal and methods of use
US6616679B1 (en) 1999-07-30 2003-09-09 Incept, Llc Rapid exchange vascular device for emboli and thrombus removal and methods of use
US6620182B1 (en) 1999-07-30 2003-09-16 Incept Llc Vascular filter having articulation region and methods of use in the ascending aorta
US7306618B2 (en) 1999-07-30 2007-12-11 Incept Llc Vascular device for emboli and thrombi removal and methods of use
US6589263B1 (en) 1999-07-30 2003-07-08 Incept Llc Vascular device having one or more articulation regions and methods of use
US7229462B2 (en) 1999-07-30 2007-06-12 Angioguard, Inc. Vascular filter system for carotid endarterectomy
US6602271B2 (en) 2000-05-24 2003-08-05 Medtronic Ave, Inc. Collapsible blood filter with optimal braid geometry
US6142987A (en) 1999-08-03 2000-11-07 Scimed Life Systems, Inc. Guided filter with support wire and methods of use
DE60117261T2 (en) 2000-05-24 2006-10-26 Medtronic Vascular, Inc., Santa Rosa vascular filters
US6245087B1 (en) 1999-08-03 2001-06-12 Embol-X, Inc. Variable expansion frame system for deploying medical devices and methods of use
US6273901B1 (en) 1999-08-10 2001-08-14 Scimed Life Systems, Inc. Thrombosis filter having a surface treatment
WO2001012082A1 (en) 1999-08-12 2001-02-22 Salviac Limited Retrieval device
US6277138B1 (en) 1999-08-17 2001-08-21 Scion Cardio-Vascular, Inc. Filter for embolic material mounted on expandable frame
DE69939753D1 (en) 1999-08-27 2008-11-27 Ev3 Inc Sliding vascular filter
US6251122B1 (en) 1999-09-02 2001-06-26 Scimed Life Systems, Inc. Intravascular filter retrieval device and method
US6146404A (en) 1999-09-03 2000-11-14 Scimed Life Systems, Inc. Removable thrombus filter
US6364895B1 (en) 1999-10-07 2002-04-02 Prodesco, Inc. Intraluminal filter
US6375670B1 (en) 1999-10-07 2002-04-23 Prodesco, Inc. Intraluminal filter
US6425909B1 (en) 1999-11-04 2002-07-30 Concentric Medical, Inc. Methods and devices for filtering fluid flow through a body structure
US6371971B1 (en) 1999-11-15 2002-04-16 Scimed Life Systems, Inc. Guidewire filter and methods of use
WO2001035858A1 (en) 1999-11-18 2001-05-25 Advanced Cardiovascular Systems, Inc. Embolic protection system and method including an emboli-capturing catheter
US6695865B2 (en) 2000-03-20 2004-02-24 Advanced Bio Prosthetic Surfaces, Ltd. Embolic protection device
US6623450B1 (en) 1999-12-17 2003-09-23 Advanced Cardiovascular Systems, Inc. System for blocking the passage of emboli through a body vessel
US6443979B1 (en) 1999-12-20 2002-09-03 Advanced Cardiovascular Systems, Inc. Expandable stent delivery sheath and method of use
US6443971B1 (en) 1999-12-21 2002-09-03 Advanced Cardiovascular Systems, Inc. System for, and method of, blocking the passage of emboli through a vessel
US6660021B1 (en) 1999-12-23 2003-12-09 Advanced Cardiovascular Systems, Inc. Intravascular device and system
WO2001045590A3 (en) 1999-12-23 2002-03-07 Percusurge Inc Strut design for an occlusion device
WO2001045592A1 (en) 1999-12-23 2001-06-28 Percusurge, Inc. Vascular filters with radiopaque markings
US6575997B1 (en) 1999-12-23 2003-06-10 Endovascular Technologies, Inc. Embolic basket
US6402771B1 (en) 1999-12-23 2002-06-11 Guidant Endovascular Solutions Snare
US6406471B1 (en) 1999-12-28 2002-06-18 Embol-X, Inc. Arterial filter with aspiration and methods of use
US6290710B1 (en) 1999-12-29 2001-09-18 Advanced Cardiovascular Systems, Inc. Embolic protection device
US6383206B1 (en) 1999-12-30 2002-05-07 Advanced Cardiovascular Systems, Inc. Embolic protection system and method including filtering elements
WO2002043595A3 (en) 2000-11-28 2003-12-18 Advanced Cardiovascular System Embolic protection devices
US6645220B1 (en) 1999-12-30 2003-11-11 Advanced Cardiovascular Systems, Inc. Embolic protection system and method including and embolic-capturing filter
US6540722B1 (en) 1999-12-30 2003-04-01 Advanced Cardiovascular Systems, Inc. Embolic protection devices
US6695813B1 (en) 1999-12-30 2004-02-24 Advanced Cardiovascular Systems, Inc. Embolic protection devices
US6342063B1 (en) 2000-01-26 2002-01-29 Scimed Life Systems, Inc. Device and method for selectively removing a thrombus filter
US6443926B1 (en) 2000-02-01 2002-09-03 Harold D. Kletschka Embolic protection device having expandable trap
DE60128207D1 (en) 2000-02-01 2007-06-14 Harold D Kletschka Angioplastievorrichtunng
US6540767B1 (en) 2000-02-08 2003-04-01 Scimed Life Systems, Inc. Recoilable thrombosis filtering device and method
US6540768B1 (en) 2000-02-09 2003-04-01 Cordis Corporation Vascular filter system
WO2001067989A3 (en) 2000-03-10 2002-09-06 Michael T Anthony Don Vascular embolism preventon device employing filters
US7214237B2 (en) 2001-03-12 2007-05-08 Don Michael T Anthony Vascular filter with improved strength and flexibility
US6485500B1 (en) 2000-03-21 2002-11-26 Advanced Cardiovascular Systems, Inc. Emboli protection system
US6632241B1 (en) 2000-03-22 2003-10-14 Endovascular Technologies, Inc. Self-expanding, pseudo-braided intravascular device
JP3849397B2 (en) 2000-03-23 2006-11-22 ニプロ株式会社 Cava filters
GB0127195D0 (en) 2000-04-20 2002-01-02 Salviac Ltd An embolic protection system
EP1149566A3 (en) 2000-04-24 2003-08-06 Cordis Corporation Vascular filter systems with guidewire and capture mechanism
US6592616B1 (en) 2000-04-28 2003-07-15 Advanced Cardiovascular Systems, Inc. System and device for minimizing embolic risk during an interventional procedure
US6706053B1 (en) 2000-04-28 2004-03-16 Advanced Cardiovascular Systems, Inc. Nitinol alloy design for sheath deployable and re-sheathable vascular devices
DE60126084T2 (en) 2000-06-23 2007-08-09 Salviac Ltd. Filter element for an embolic protection device
US6565591B2 (en) 2000-06-23 2003-05-20 Salviac Limited Medical device
US6663650B2 (en) 2000-06-29 2003-12-16 Concentric Medical, Inc. Systems, methods and devices for removing obstructions from a blood vessel
WO2002005888A1 (en) 2000-06-30 2002-01-24 Viacor Incorporated Intravascular filter with debris entrapment mechanism
US6482222B1 (en) 2000-07-11 2002-11-19 Rafael Medical Technologies Inc. Intravascular filter
EP1172073A1 (en) 2000-07-13 2002-01-16 Cordis Corporation Vascular filter system with guidewire and capture mechanism
US6656202B2 (en) 2000-07-14 2003-12-02 Advanced Cardiovascular Systems, Inc. Embolic protection systems
US6575995B1 (en) 2000-07-14 2003-06-10 Advanced Cardiovascular Systems, Inc. Expandable cage embolic material filter system and method
US6599307B1 (en) 2001-06-29 2003-07-29 Advanced Cardiovascular Systems, Inc. Filter device for embolic protection systems
US20020183873A1 (en) 2000-07-21 2002-12-05 Haruyuki Miura Recording device, reproducing device and recording/reproducing system
US6740061B1 (en) 2000-07-28 2004-05-25 Ev3 Inc. Distal protection device
EP1368088A4 (en) 2000-08-04 2005-11-16 Univ Duke Temporary vascular filters and methods
US6544279B1 (en) 2000-08-09 2003-04-08 Incept, Llc Vascular device for emboli, thrombus and foreign body removal and methods of use
US6394978B1 (en) 2000-08-09 2002-05-28 Advanced Cardiovascular Systems, Inc. Interventional procedure expandable balloon expansion enabling system and method
US6485501B1 (en) 2000-08-11 2002-11-26 Cordis Corporation Vascular filter system with guidewire and capture mechanism
US6558405B1 (en) 2000-08-29 2003-05-06 Advanced Cardiovascular Systems, Inc. Embolic filter
US6616681B2 (en) 2000-10-05 2003-09-09 Scimed Life Systems, Inc. Filter delivery and retrieval device
US20020072730A1 (en) 2000-10-12 2002-06-13 Mcgill Scott A. Methods and apparatus for protecting the proximal end of a medical device
US20020082525A1 (en) 2000-10-18 2002-06-27 Oslund John C. Rapid exchange delivery catheter
WO2002032496A9 (en) 2000-10-18 2003-05-01 Nmt Medical Inc Over-the-wire interlock attachment/detachment mechanism
US6582447B1 (en) 2000-10-20 2003-06-24 Angiodynamics, Inc. Convertible blood clot filter
US6589265B1 (en) 2000-10-31 2003-07-08 Endovascular Technologies, Inc. Intrasaccular embolic device
US6616680B1 (en) 2000-11-01 2003-09-09 Joseph M. Thielen Distal protection and delivery system and method
US6602272B2 (en) 2000-11-02 2003-08-05 Advanced Cardiovascular Systems, Inc. Devices configured from heat shaped, strain hardened nickel-titanium
US6893451B2 (en) 2000-11-09 2005-05-17 Advanced Cardiovascular Systems, Inc. Apparatus for capturing objects beyond an operative site utilizing a capture device delivered on a medical guide wire
US6582448B1 (en) 2000-12-21 2003-06-24 Advanced Cardiovascular Systems, Inc. Vessel occlusion device for embolic protection system
US6663651B2 (en) 2001-01-16 2003-12-16 Incept Llc Systems and methods for vascular filter retrieval
US6936059B2 (en) 2001-01-16 2005-08-30 Scimed Life Systems, Inc. Endovascular guidewire filter and methods of use
US7169165B2 (en) 2001-01-16 2007-01-30 Boston Scientific Scimed, Inc. Rapid exchange sheath for deployment of medical devices and methods of use
US6610077B1 (en) 2001-01-23 2003-08-26 Endovascular Technologies, Inc. Expandable emboli filter and thrombectomy device
US6689151B2 (en) 2001-01-25 2004-02-10 Scimed Life Systems, Inc. Variable wall thickness for delivery sheath housing
US20020128680A1 (en) 2001-01-25 2002-09-12 Pavlovic Jennifer L. Distal protection device with electrospun polymer fiber matrix
US6979343B2 (en) 2001-02-14 2005-12-27 Ev3 Inc. Rolled tip recovery catheter
US6840950B2 (en) 2001-02-20 2005-01-11 Scimed Life Systems, Inc. Low profile emboli capture device
US6569184B2 (en) 2001-02-27 2003-05-27 Advanced Cardiovascular Systems, Inc. Recovery system for retrieving an embolic protection device
US6974468B2 (en) 2001-02-28 2005-12-13 Scimed Life Systems, Inc. Filter retrieval catheter
US20020123755A1 (en) 2001-03-01 2002-09-05 Scimed Life Systems, Inc. Embolic protection filter delivery sheath
US7226464B2 (en) 2001-03-01 2007-06-05 Scimed Life Systems, Inc. Intravascular filter retrieval device having an actuatable dilator tip
US6562058B2 (en) 2001-03-02 2003-05-13 Jacques Seguin Intravascular filter system
US20020128679A1 (en) 2001-03-08 2002-09-12 Embol-X, Inc. Cerebral protection during carotid endarterectomy and methods of use
US8298160B2 (en) 2001-03-16 2012-10-30 Ev3 Inc. Wire convertible from over-the-wire length to rapid exchange length
US6602269B2 (en) 2001-03-30 2003-08-05 Scimed Life Systems Embolic devices capable of in-situ reinforcement
US20020161395A1 (en) 2001-04-03 2002-10-31 Nareak Douk Guide wire apparatus for prevention of distal atheroembolization
US6866677B2 (en) 2001-04-03 2005-03-15 Medtronic Ave, Inc. Temporary intraluminal filter guidewire and methods of use
US6911036B2 (en) 2001-04-03 2005-06-28 Medtronic Vascular, Inc. Guidewire apparatus for temporary distal embolic protection
US7044958B2 (en) 2001-04-03 2006-05-16 Medtronic Vascular, Inc. Temporary device for capturing embolic material
US6818006B2 (en) 2001-04-03 2004-11-16 Medtronic Vascular, Inc. Temporary intraluminal filter guidewire
US6706055B2 (en) 2001-04-03 2004-03-16 Medtronic Ave Inc. Guidewire apparatus for temporary distal embolic protection
US6428559B1 (en) 2001-04-03 2002-08-06 Cordis Corporation Removable, variable-diameter vascular filter system
WO2002083225A1 (en) 2001-04-10 2002-10-24 Fisher John S Emboli capturing device
US6436121B1 (en) 2001-04-30 2002-08-20 Paul H. Blom Removable blood filter
US6645223B2 (en) 2001-04-30 2003-11-11 Advanced Cardiovascular Systems, Inc. Deployment and recovery control systems for embolic protection devices
US6746469B2 (en) 2001-04-30 2004-06-08 Advanced Cardiovascular Systems, Inc. Balloon actuated apparatus having multiple embolic filters, and method of use
US6635070B2 (en) 2001-05-21 2003-10-21 Bacchus Vascular, Inc. Apparatus and methods for capturing particulate material within blood vessels
US20020183783A1 (en) 2001-06-04 2002-12-05 Shadduck John H. Guidewire for capturing emboli in endovascular interventions
US20020188314A1 (en) 2001-06-07 2002-12-12 Microvena Corporation Radiopaque distal embolic protection device
US6596011B2 (en) 2001-06-12 2003-07-22 Cordis Corporation Emboli extraction catheter and vascular filter system
JP4294470B2 (en) 2001-06-14 2009-07-15 クック インコーポレイテッド Intravascular filter
US6551341B2 (en) 2001-06-14 2003-04-22 Advanced Cardiovascular Systems, Inc. Devices configured from strain hardened Ni Ti tubing
US6783538B2 (en) 2001-06-18 2004-08-31 Rex Medical, L.P Removable vein filter
US6793665B2 (en) 2001-06-18 2004-09-21 Rex Medical, L.P. Multiple access vein filter
US6623506B2 (en) 2001-06-18 2003-09-23 Rex Medical, L.P Vein filter
US20030125764A1 (en) 2001-06-27 2003-07-03 Eamon Brady Catheter
US7780693B2 (en) 2001-06-27 2010-08-24 Salviac Limited Catheter
US6575996B1 (en) 2001-06-29 2003-06-10 Advanced Cardiovascular Systems, Inc. Filter device for embolic protection system
US6551342B1 (en) 2001-08-24 2003-04-22 Endovascular Technologies, Inc. Embolic filter
US6652557B1 (en) 2001-08-29 2003-11-25 Macdonald Kenneth A. Mechanism for capturing debris generated during vascular procedures
US6638294B1 (en) 2001-08-30 2003-10-28 Advanced Cardiovascular Systems, Inc. Self furling umbrella frame for carotid filter
US6592606B2 (en) 2001-08-31 2003-07-15 Advanced Cardiovascular Systems, Inc. Hinged short cage for an embolic protection device
US6730185B2 (en) * 2001-09-05 2004-05-04 Rock Ridge Technologies Co. Adhesive leaflet assemblies
EP1425055A4 (en) 2001-09-10 2008-06-11 Rafael Medical Technologies In Intravascular devices, retrieval systems, and corresponding methods
US6616682B2 (en) 2001-09-19 2003-09-09 Jomed Gmbh Methods and apparatus for distal protection during a medical procedure
JP2003098897A (en) * 2001-09-25 2003-04-04 Canon Inc Heating device and image formation device
US20030204168A1 (en) 2002-04-30 2003-10-30 Gjalt Bosma Coated vascular devices
US8262689B2 (en) 2001-09-28 2012-09-11 Advanced Cardiovascular Systems, Inc. Embolic filtering devices
US6755847B2 (en) 2001-10-05 2004-06-29 Scimed Life Systems, Inc. Emboli capturing device and method of manufacture therefor
US20030069597A1 (en) 2001-10-10 2003-04-10 Scimed Life Systems, Inc. Loading tool
US20030078614A1 (en) 2001-10-18 2003-04-24 Amr Salahieh Vascular embolic filter devices and methods of use therefor
US6887257B2 (en) 2001-10-19 2005-05-03 Incept Llc Vascular embolic filter exchange devices and methods of use thereof
US20030083692A1 (en) 2001-10-29 2003-05-01 Scimed Life Systems, Inc. Distal protection device and method of use thereof
US20030109824A1 (en) 2001-11-07 2003-06-12 Microvena Corporation Distal protection device with local drug delivery to maintain patency
US6939362B2 (en) 2001-11-27 2005-09-06 Advanced Cardiovascular Systems, Inc. Offset proximal cage for embolic filtering devices
DE60221289T2 (en) 2001-11-29 2008-04-10 Cook Inc., Bloomington Supply system for medical devices
US6890340B2 (en) 2001-11-29 2005-05-10 Medtronic Vascular, Inc. Apparatus for temporary intraluminal protection
US6837898B2 (en) 2001-11-30 2005-01-04 Advanced Cardiovascular Systems, Inc. Intraluminal delivery system for an attachable treatment device
WO2003047648A3 (en) 2001-12-05 2003-10-09 Sagax Inc Endovascular device for entrapment of particulate matter and method for use
US7153320B2 (en) 2001-12-13 2006-12-26 Scimed Life Systems, Inc. Hydraulic controlled retractable tip filter retrieval catheter
US6793666B2 (en) 2001-12-18 2004-09-21 Scimed Life Systems, Inc. Distal protection mechanically attached filter cartridge
EP1455686A2 (en) 2001-12-21 2004-09-15 Salviac Limited A support frame for an embolic protection device
US7241304B2 (en) 2001-12-21 2007-07-10 Advanced Cardiovascular Systems, Inc. Flexible and conformable embolic filtering devices
US6958074B2 (en) 2002-01-07 2005-10-25 Cordis Corporation Releasable and retrievable vascular filter system
US8647359B2 (en) 2002-01-10 2014-02-11 Boston Scientific Scimed, Inc. Distal protection filter
US6932830B2 (en) 2002-01-10 2005-08-23 Scimed Life Systems, Inc. Disc shaped filter
US20030135162A1 (en) 2002-01-17 2003-07-17 Scimed Life Systems, Inc. Delivery and retrieval manifold for a distal protection filter
EP1469790B1 (en) 2002-01-25 2016-10-19 Atritech, Inc. Atrial appendage blood filtration systems
US20030144686A1 (en) 2002-01-30 2003-07-31 Embol-X, Inc. Distal filtration devices and methods of use during aortic procedures
US7344549B2 (en) 2002-01-31 2008-03-18 Advanced Cardiovascular Systems, Inc. Expandable cages for embolic filtering devices
US20040012951A1 (en) * 2002-02-06 2004-01-22 Pylkki Russell John Fire safety window
US6997938B2 (en) 2002-02-12 2006-02-14 Scimed Life Systems, Inc. Embolic protection device
US20030158574A1 (en) 2002-02-15 2003-08-21 Esch Brady D. Flow-through aortic flow divider for cerebral and coronary embolic protection
US7118539B2 (en) 2002-02-26 2006-10-10 Scimed Life Systems, Inc. Articulating guide wire for embolic protection and methods of use
WO2003073961A1 (en) 2002-03-05 2003-09-12 Salviac Limited System with embolic filter and retracting snare
US6773448B2 (en) 2002-03-08 2004-08-10 Ev3 Inc. Distal protection devices having controllable wire motion
US7192434B2 (en) 2002-03-08 2007-03-20 Ev3 Inc. Vascular protection devices and methods of use
US20030176886A1 (en) 2002-03-12 2003-09-18 Wholey Mark H. Vascular catheter with expanded distal tip for receiving a thromboembolic protection device and method of use
US20030176884A1 (en) 2002-03-12 2003-09-18 Marwane Berrada Everted filter device
US7029440B2 (en) 2002-03-13 2006-04-18 Scimed Life Systems, Inc. Distal protection filter and method of manufacture
US7575602B2 (en) * 2002-03-19 2009-08-18 The Board Of Trustees Of The University Of Illinois System and method for prosthetic fitting and balancing in joints
US20030187495A1 (en) 2002-04-01 2003-10-02 Cully Edward H. Endoluminal devices, embolic filters, methods of manufacture and use
US20030191493A1 (en) 2002-04-05 2003-10-09 Epstein Gordon H. Device for clot retrieval and distal protection
US20030199819A1 (en) 2002-04-17 2003-10-23 Beck Robert C. Filter wire system
WO2003088805A3 (en) 2002-04-19 2004-05-21 Salviac Ltd A medical device
WO2003088869A3 (en) 2002-04-19 2004-03-25 Salviac Ltd A medical device
US8070769B2 (en) 2002-05-06 2011-12-06 Boston Scientific Scimed, Inc. Inverted embolic protection filter
US7060082B2 (en) 2002-05-06 2006-06-13 Scimed Life Systems, Inc. Perfusion guidewire in combination with a distal filter
DE60324787D1 (en) 2002-05-10 2009-01-02 Salviac Ltd System for filtering of emboli
WO2003094790A3 (en) 2002-05-13 2004-04-08 Salviac Ltd Catheter system with procedural catheter and embolic proctection system
US7585309B2 (en) 2002-05-16 2009-09-08 Boston Scientific Scimed, Inc. Aortic filter
US7001406B2 (en) 2002-05-23 2006-02-21 Scimed Life Systems Inc. Cartridge embolic protection filter and methods of use
US7959584B2 (en) 2002-05-29 2011-06-14 Boston Scientific Scimed, Inc. Dedicated distal protection guidewires
US7326224B2 (en) 2002-06-11 2008-02-05 Boston Scientific Scimed, Inc. Shaft and wire lock
US7717934B2 (en) 2002-06-14 2010-05-18 Ev3 Inc. Rapid exchange catheters usable with embolic protection devices
US7166120B2 (en) 2002-07-12 2007-01-23 Ev3 Inc. Catheter with occluding cuff
US20060069597A1 (en) * 2004-09-30 2006-03-30 Wittrock Robert J Pegging resources to shipments in a pre-existing production plan
FI20105951A0 (en) 2010-09-17 2010-09-17 Waertsilae Finland Oy start the internal combustion engine
US9046098B2 (en) 2011-08-03 2015-06-02 Artemis Intelligent Power Limited Face sealing annular valve for a fluid-working machine
EP2583568A1 (en) 2011-10-18 2013-04-24 Purac Biochem N.V. Preservative combinations comprising vanillin and cinnamic acid

Patent Citations (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3435824A (en) * 1966-10-27 1969-04-01 Herminio Gamponia Surgical apparatus and related process
US3952747A (en) * 1974-03-28 1976-04-27 Kimmell Jr Garman O Filter and filter insertion instrument
US4425908A (en) * 1981-10-22 1984-01-17 Beth Israel Hospital Blood clot filter
US4423725A (en) * 1982-03-31 1984-01-03 Baran Ostap E Multiple surgical cuff
US4493711A (en) * 1982-06-25 1985-01-15 Thomas J. Fogarty Tubular extrusion catheter
US4512762A (en) * 1982-11-23 1985-04-23 The Beth Israel Hospital Association Method of treatment of atherosclerosis and a balloon catheter for same
US4643187A (en) * 1983-05-30 1987-02-17 Olympus Optical Co., Ltd. High-frequency incising and excising instrument
US4585000A (en) * 1983-09-28 1986-04-29 Cordis Corporation Expandable device for treating intravascular stenosis
US4807626A (en) * 1985-02-14 1989-02-28 Mcgirr Douglas B Stone extractor and method
US4650466A (en) * 1985-11-01 1987-03-17 Angiobrade Partners Angioplasty device
US4723549A (en) * 1986-09-18 1988-02-09 Wholey Mark H Method and apparatus for dilating blood vessels
US4817600A (en) * 1987-05-22 1989-04-04 Medi-Tech, Inc. Implantable filter
US4794928A (en) * 1987-06-10 1989-01-03 Kletschka Harold D Angioplasty device and method of using the same
US4990156A (en) * 1988-06-21 1991-02-05 Lefebvre Jean Marie Filter for medical use
US5011488A (en) * 1988-12-07 1991-04-30 Robert Ginsburg Thrombus extraction system
US5092839A (en) * 1989-09-29 1992-03-03 Kipperman Robert M Coronary thrombectomy
US5108419A (en) * 1990-08-16 1992-04-28 Evi Corporation Endovascular filter and method for use thereof
US5100423A (en) * 1990-08-21 1992-03-31 Medical Engineering & Development Institute, Inc. Ablation catheter
US5178158A (en) * 1990-10-29 1993-01-12 Boston Scientific Corporation Convertible guidewire-catheter with soft tip
US5405329A (en) * 1991-01-08 1995-04-11 Durand; Alain J. Intravascular multi-lumen catheter, capable of being implanted by "tunnelling"
US5192284A (en) * 1992-01-10 1993-03-09 Pleatman Mark A Surgical collector and extractor
US5387219A (en) * 1992-09-23 1995-02-07 Target Therapeutics Medical retrieval snare with coil wrapped loop
US5383887A (en) * 1992-12-28 1995-01-24 Celsa Lg Device for selectively forming a temporary blood filter
US5897567A (en) * 1993-04-29 1999-04-27 Scimed Life Systems, Inc. Expandable intravascular occlusion material removal devices and methods of use
US5720764A (en) * 1994-06-11 1998-02-24 Naderlinger; Eduard Vena cava thrombus filter
US5709704A (en) * 1994-11-30 1998-01-20 Boston Scientific Corporation Blood clot filtering
US5593394A (en) * 1995-01-24 1997-01-14 Kanesaka; Nozomu Shaft for a catheter system
US6168604B1 (en) * 1995-10-06 2001-01-02 Metamorphic Surgical Devices, Llc Guide wire device for removing solid objects from body canals
US6013093A (en) * 1995-11-28 2000-01-11 Boston Scientific Corporation Blood clot filtering
US5895398A (en) * 1996-02-02 1999-04-20 The Regents Of The University Of California Method of using a clot capture coil
US6010522A (en) * 1996-07-17 2000-01-04 Embol-X, Inc. Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries
US5876367A (en) * 1996-12-05 1999-03-02 Embol-X, Inc. Cerebral protection during carotid endarterectomy and downstream vascular protection during other surgeries
US5882329A (en) * 1997-02-12 1999-03-16 Prolifix Medical, Inc. Apparatus and method for removing stenotic material from stents
US6053932A (en) * 1997-03-06 2000-04-25 Scimed Life Systems, Inc. Distal protection device
US6027520A (en) * 1997-05-08 2000-02-22 Embol-X, Inc. Percutaneous catheter and guidewire having filter and medical device deployment capabilities
US6042598A (en) * 1997-05-08 2000-03-28 Embol-X Inc. Method of protecting a patient from embolization during cardiac surgery
US6537297B2 (en) * 1997-05-08 2003-03-25 Embol-X, Inc. Methods of protecting a patient from embolization during surgery
US6048645A (en) * 1997-08-21 2000-04-11 Valence Technology, Inc. Method of preparing lithium ion electrochemical cells
US5895410A (en) * 1997-09-12 1999-04-20 B. Braun Medical, Inc. Introducer for an expandable vascular occlusion device
US6361545B1 (en) * 1997-09-26 2002-03-26 Cardeon Corporation Perfusion filter catheter
US20020002384A1 (en) * 1997-11-07 2002-01-03 Paul Gilson Embolic protection device
US20030032977A1 (en) * 1997-11-07 2003-02-13 Salviac Limited Filter element with retractable guidewire tip
US20030009189A1 (en) * 1997-11-07 2003-01-09 Salviac Limited Embolic protection device
US20020026213A1 (en) * 1997-11-07 2002-02-28 Paul Gilson Embolic protection device
US6336934B1 (en) * 1997-11-07 2002-01-08 Salviac Limited Embolic protection device
US6206868B1 (en) * 1998-03-13 2001-03-27 Arteria Medical Science, Inc. Protective device and method against embolization during treatment of carotid artery disease
US6511492B1 (en) * 1998-05-01 2003-01-28 Microvention, Inc. Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders
US6530936B1 (en) * 1998-06-03 2003-03-11 Yeong Seok Yun Apparatus for harvesting cartilage
US20030060782A1 (en) * 1998-06-04 2003-03-27 Arani Bose Endovascular thin film devices and methods for treating and preventing stroke
US6051014A (en) * 1998-10-13 2000-04-18 Embol-X, Inc. Percutaneous filtration catheter for valve repair surgery and methods of use
US20030040772A1 (en) * 1999-02-01 2003-02-27 Hideki Hyodoh Delivery devices
US20030060844A1 (en) * 1999-02-12 2003-03-27 Thomas Borillo Vascular filter system
US6171327B1 (en) * 1999-02-24 2001-01-09 Scimed Life Systems, Inc. Intravascular filter and method
US6355051B1 (en) * 1999-03-04 2002-03-12 Bioguide Consulting, Inc. Guidewire filter device
US6537296B2 (en) * 1999-04-01 2003-03-25 Scion Cardio-Vascular, Inc. Locking frame, filter and deployment system
US6517559B1 (en) * 1999-05-03 2003-02-11 O'connell Paul T. Blood filter and method for treating vascular disease
US6176849B1 (en) * 1999-05-21 2001-01-23 Scimed Life Systems, Inc. Hydrophilic lubricity coating for medical devices comprising a hydrophobic top coat
US6179859B1 (en) * 1999-07-16 2001-01-30 Baff Llc Emboli filtration system and methods of use
US6179861B1 (en) * 1999-07-30 2001-01-30 Incept Llc Vascular device having one or more articulation regions and methods of use
US6214026B1 (en) * 1999-07-30 2001-04-10 Incept Llc Delivery system for a vascular device with articulation region
US20020022858A1 (en) * 1999-07-30 2002-02-21 Demond Jackson F. Vascular device for emboli removal having suspension strut and methods of use
US6203561B1 (en) * 1999-07-30 2001-03-20 Incept Llc Integrated vascular device having thrombectomy element and vascular filter and methods of use
US6346116B1 (en) * 1999-08-03 2002-02-12 Medtronic Ave, Inc. Distal protection device
US6168579B1 (en) * 1999-08-04 2001-01-02 Scimed Life Systems, Inc. Filter flush system and methods of use
US6348056B1 (en) * 1999-08-06 2002-02-19 Scimed Life Systems, Inc. Medical retrieval device with releasable retrieval basket
US6511497B1 (en) * 1999-09-14 2003-01-28 Cormedics Gmbh Vascular filter system
US20020032460A1 (en) * 1999-09-21 2002-03-14 Kusleika Richard S. Temporary vascular filter
US6340364B2 (en) * 1999-10-22 2002-01-22 Nozomu Kanesaka Vascular filtering device
US6530940B2 (en) * 1999-10-25 2003-03-11 John S. Fisher Emboli capturing device
US6171328B1 (en) * 1999-11-09 2001-01-09 Embol-X, Inc. Intravascular catheter filter with interlocking petal design and methods of use
US20020026211A1 (en) * 1999-12-23 2002-02-28 Farhad Khosravi Vascular device having emboli and thrombus removal element and methods of use
US20030028238A1 (en) * 1999-12-30 2003-02-06 Burkett David H. Catheter apparatus for treating occluded vessels and filtering embolic debris and method of use
US6511503B1 (en) * 1999-12-30 2003-01-28 Advanced Cardiovascular Systems, Inc. Catheter apparatus for treating occluded vessels and filtering embolic debris and method of use
US6361546B1 (en) * 2000-01-13 2002-03-26 Endotex Interventional Systems, Inc. Deployable recoverable vascular filter and methods for use
US6517550B1 (en) * 2000-02-02 2003-02-11 Board Of Regents, The University Of Texas System Foreign body retrieval device
US6514273B1 (en) * 2000-03-22 2003-02-04 Endovascular Technologies, Inc. Device for removal of thrombus through physiological adhesion
US6520978B1 (en) * 2000-05-15 2003-02-18 Intratherapeutics, Inc. Emboli filter
US6527746B1 (en) * 2000-08-03 2003-03-04 Ev3, Inc. Back-loading catheter
US20020022860A1 (en) * 2000-08-18 2002-02-21 Borillo Thomas E. Expandable implant devices for filtering blood flow from atrial appendages
US6511496B1 (en) * 2000-09-12 2003-01-28 Advanced Cardiovascular Systems, Inc. Embolic protection device for use in interventional procedures
US6537294B1 (en) * 2000-10-17 2003-03-25 Advanced Cardiovascular Systems, Inc. Delivery systems for embolic filter devices
US6506203B1 (en) * 2000-12-19 2003-01-14 Advanced Cardiovascular Systems, Inc. Low profile sheathless embolic protection system
US6506205B2 (en) * 2001-02-20 2003-01-14 Mark Goldberg Blood clot filtering system
US6537295B2 (en) * 2001-03-06 2003-03-25 Scimed Life Systems, Inc. Wire and lock mechanism
US20030057156A1 (en) * 2001-03-08 2003-03-27 Dean Peterson Atrial filter implants
US20030004536A1 (en) * 2001-06-29 2003-01-02 Boylan John F. Variable thickness embolic filtering devices and method of manufacturing the same
US20030004537A1 (en) * 2001-06-29 2003-01-02 Boyle William J. Delivery and recovery sheaths for medical devices
US20030009188A1 (en) * 2001-07-02 2003-01-09 Linder Richard J. Methods, systems, and devices for deploying a filter from a filter device
US20030004540A1 (en) * 2001-07-02 2003-01-02 Rubicon Medical, Inc. Methods, systems, and devices for deploying an embolic protection filter
US20030004539A1 (en) * 2001-07-02 2003-01-02 Linder Richard J. Methods, systems, and devices for providing embolic protection and removing embolic material
US20030004541A1 (en) * 2001-07-02 2003-01-02 Rubicon Medical, Inc. Methods, systems, and devices for providing embolic protection
US20030023265A1 (en) * 2001-07-13 2003-01-30 Forber Simon John Vascular protection system
US20030015206A1 (en) * 2001-07-18 2003-01-23 Roth Noah M. Integral vascular filter system
US20030018354A1 (en) * 2001-07-18 2003-01-23 Roth Noah M. Integral vascular filter system with core wire activation
US6533800B1 (en) * 2001-07-25 2003-03-18 Coaxia, Inc. Devices and methods for preventing distal embolization using flow reversal in arteries having collateral blood flow
US20030032941A1 (en) * 2001-08-13 2003-02-13 Boyle William J. Convertible delivery systems for medical devices
US20030042186A1 (en) * 2001-08-31 2003-03-06 Boyle William J. Embolic protection devices one way porous membrane
US20030045898A1 (en) * 2001-09-06 2003-03-06 Harrison William J. Embolic protection basket
US20030060843A1 (en) * 2001-09-27 2003-03-27 Don Boucher Vascular filter system with encapsulated filter

Cited By (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040068288A1 (en) * 1999-12-23 2004-04-08 Olin Palmer Intravascular device and system
US20110004238A1 (en) * 1999-12-23 2011-01-06 Abbott Laboratories Intravascular device and system
US8137377B2 (en) 1999-12-23 2012-03-20 Abbott Laboratories Embolic basket
US8142442B2 (en) 1999-12-23 2012-03-27 Abbott Laboratories Snare
US7780694B2 (en) 1999-12-23 2010-08-24 Advanced Cardiovascular Systems, Inc. Intravascular device and system
US7918820B2 (en) 1999-12-30 2011-04-05 Advanced Cardiovascular Systems, Inc. Device for, and method of, blocking emboli in vessels such as blood arteries
US8845583B2 (en) 1999-12-30 2014-09-30 Abbott Cardiovascular Systems Inc. Embolic protection devices
US20030212361A1 (en) * 1999-12-30 2003-11-13 Boyle William J. Embolic protection devices
US20100004674A1 (en) * 1999-12-30 2010-01-07 Advanced Cardiovascular Systems, Inc. Device for, and method of, blocking emboli in vessels such as blood arteries
US20040167568A1 (en) * 1999-12-30 2004-08-26 Boyle William J. Embolic protection devices
US20090254118A1 (en) * 2000-07-13 2009-10-08 Advanced Cardiovascular Systems, Inc. Embolic protection guide wire
US8177791B2 (en) 2000-07-13 2012-05-15 Abbott Cardiovascular Systems Inc. Embolic protection guide wire
US20060095069A1 (en) * 2000-07-13 2006-05-04 Shah Niraj A Embolic protection guide wire
US20090030445A1 (en) * 2000-10-17 2009-01-29 Advanced Cardiovascular Systems, Inc. Delivery sysems for embolic filter devices
US20080215084A1 (en) * 2000-10-17 2008-09-04 Advanced Cardiovascular Systems, Inc. Delivery systems for embolic filter devices
US20050222583A1 (en) * 2000-11-09 2005-10-06 Cano Gerald G Apparatus for capturing objects beyond an operative site utilizing a capture device delivered on a medical guide wire
US20090228036A1 (en) * 2000-11-09 2009-09-10 Advanced Cardiovascular Systems, Inc. Apparatus for capturing objects beyond an operative site utilizing a capture device delivered on a medical guide wire
US20100121374A1 (en) * 2000-12-19 2010-05-13 Advanced Cardiovascular Systems, Inc. Sheathless embolic protection system
US7931666B2 (en) 2000-12-19 2011-04-26 Advanced Cardiovascular Systems, Inc. Sheathless embolic protection system
US7662166B2 (en) 2000-12-19 2010-02-16 Advanced Cardiocascular Systems, Inc. Sheathless embolic protection system
US20060129183A1 (en) * 2000-12-19 2006-06-15 Advanced Cardiovascular Systems Sheathless embolic protection system
US20040167567A1 (en) * 2001-03-23 2004-08-26 Cano Gerald G. Method and apparatus for capturing objects beyond an operative site in medical procedures
US20040088002A1 (en) * 2001-04-30 2004-05-06 Boyle William J. Deployment and recovery control systems for embolic protection devices
US20050228439A1 (en) * 2001-06-01 2005-10-13 Andrews Christopher C Delivery and recovery system for embolic protection system
US20070276429A1 (en) * 2001-06-29 2007-11-29 Advanced Cardiovascular Systems, Inc. Filter device for embolic protection systems
US20030004536A1 (en) * 2001-06-29 2003-01-02 Boylan John F. Variable thickness embolic filtering devices and method of manufacturing the same
US8016854B2 (en) 2001-06-29 2011-09-13 Abbott Cardiovascular Systems Inc. Variable thickness embolic filtering devices and methods of manufacturing the same
US7959646B2 (en) 2001-06-29 2011-06-14 Abbott Cardiovascular Systems Inc. Filter device for embolic protection systems
US20030032941A1 (en) * 2001-08-13 2003-02-13 Boyle William J. Convertible delivery systems for medical devices
US20100049305A1 (en) * 2001-08-13 2010-02-25 Advanced Cardiovascular Systems, Inc. Convertible delivery systems for medical devices
US7959647B2 (en) 2001-08-30 2011-06-14 Abbott Cardiovascular Systems Inc. Self furling umbrella frame for carotid filter
US7842064B2 (en) 2001-08-31 2010-11-30 Advanced Cardiovascular Systems, Inc. Hinged short cage for an embolic protection device
US8262689B2 (en) 2001-09-28 2012-09-11 Advanced Cardiovascular Systems, Inc. Embolic filtering devices
US20030065354A1 (en) * 2001-09-28 2003-04-03 Boyle William J. Embolic filtering devices
US20050075663A1 (en) * 2001-11-27 2005-04-07 Boyle William J. Offset proximal cage for embolic filtering devices
US20030120303A1 (en) * 2001-12-21 2003-06-26 Boyle William J. Flexible and conformable embolic filtering devices
US7972356B2 (en) 2001-12-21 2011-07-05 Abbott Cardiovascular Systems, Inc. Flexible and conformable embolic filtering devices
US20050182441A1 (en) * 2002-06-26 2005-08-18 Denison Andy E. Embolic filtering devices for bifurcated vessels
US20100004673A1 (en) * 2002-06-26 2010-01-07 Advanced Cardiovascular Systems, Inc. Embolic filtering devices for bifurcated vessels
US7815660B2 (en) 2002-09-30 2010-10-19 Advanced Cardivascular Systems, Inc. Guide wire with embolic filtering attachment
US20040064099A1 (en) * 2002-09-30 2004-04-01 Chiu Jessica G. Intraluminal needle injection substance delivery system with filtering capability
US20040093009A1 (en) * 2002-09-30 2004-05-13 Denison Andy E. Embolic filtering devices
US8029530B2 (en) 2002-09-30 2011-10-04 Abbott Cardiovascular Systems Inc. Guide wire with embolic filtering attachment
US20110029008A1 (en) * 2002-09-30 2011-02-03 Advanced Cardiovascular Systems, Inc. Guide wire with embolic filtering attachment
US7976560B2 (en) 2002-09-30 2011-07-12 Abbott Cardiovascular Systems Inc. Embolic filtering devices
US7678131B2 (en) 2002-10-31 2010-03-16 Advanced Cardiovascular Systems, Inc. Single-wire expandable cages for embolic filtering devices
US20070149997A1 (en) * 2002-10-31 2007-06-28 Muller Paul F Single-wire expandable cages for embolic filtering devices
US20050004595A1 (en) * 2003-02-27 2005-01-06 Boyle William J. Embolic filtering devices
US20040172055A1 (en) * 2003-02-27 2004-09-02 Huter Scott J. Embolic filtering devices
US8591540B2 (en) 2003-02-27 2013-11-26 Abbott Cardiovascular Systems Inc. Embolic filtering devices
US7892251B1 (en) 2003-11-12 2011-02-22 Advanced Cardiovascular Systems, Inc. Component for delivering and locking a medical device to a guide wire
US7678129B1 (en) 2004-03-19 2010-03-16 Advanced Cardiovascular Systems, Inc. Locking component for an embolic filter assembly
US7879065B2 (en) 2004-03-19 2011-02-01 Advanced Cardiovascular Systems, Inc. Locking component for an embolic filter assembly
US20100152769A1 (en) * 2004-03-19 2010-06-17 Advanced Cardiovascular Systems, Inc. Locking component for an embolic filter assembly
US20070162071A1 (en) * 2004-03-19 2007-07-12 Burkett David H Locking component for an embolic filter assembly
US8308753B2 (en) 2004-03-19 2012-11-13 Advanced Cardiovascular Systems, Inc. Locking component for an embolic filter assembly
WO2006104910A1 (en) * 2005-03-29 2006-10-05 Boston Scientific Limited Methods and apparatuses for disposition of a medical device onto an elongate medical device
US9259305B2 (en) 2005-03-31 2016-02-16 Abbott Cardiovascular Systems Inc. Guide wire locking mechanism for rapid exchange and other catheter systems
US20070088382A1 (en) * 2005-10-13 2007-04-19 Bei Nianjiong J Embolic protection recovery catheter assembly
US8216209B2 (en) 2007-05-31 2012-07-10 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
US7867273B2 (en) 2007-06-27 2011-01-11 Abbott Laboratories Endoprostheses for peripheral arteries and other body vessels
US9295393B2 (en) 2012-11-09 2016-03-29 Elwha Llc Embolism deflector
US9414752B2 (en) 2012-11-09 2016-08-16 Elwha Llc Embolism deflector
US9579116B1 (en) 2015-08-06 2017-02-28 Kp Medcure, Inc. Axial lengthening thrombus capture system
US9636206B2 (en) 2015-08-06 2017-05-02 Kp Medcure, Inc. Axial lengthening thrombus capture system
US9744024B2 (en) 2015-08-06 2017-08-29 Kp Medcure, Inc. Axial lengthening thrombus capture system
US9844386B2 (en) 2015-08-06 2017-12-19 Kp Medcure, Inc. Axial lengthening thrombus capture system

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