US20030130871A1 - Patient data mining for clinical trials - Google Patents

Patient data mining for clinical trials Download PDF

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US20030130871A1
US20030130871A1 US10287098 US28709802A US2003130871A1 US 20030130871 A1 US20030130871 A1 US 20030130871A1 US 10287098 US10287098 US 10287098 US 28709802 A US28709802 A US 28709802A US 2003130871 A1 US2003130871 A1 US 2003130871A1
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method
information
patient
persons
specified criteria
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US10287098
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R. Rao
Satrajit Misra
Linda Best
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Siemens Medical Solutions USA Inc
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Siemens Medical Solutions USA Inc
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Abstract

The present invention provides a system and method for selecting prospective patients for a clinical trial. In various embodiments, a clinical trials brokerage is configured to receive requests from drug companies for lists of persons meeting specified criteria for clinical trials. Patient records are retrieved from a structured computerized patient record (CPR) data warehouse populated with comprehensive patient information mined from unstructured hospital records. A list of persons for whom consent was obtained can be outputted and forwarded to the entity interested in performing the clinical trial and which requested the list. Anonymity of a patient can be maintained until the patient provides consent to participate in the clinical trial.

Description

    CROSS REFERENCE TO RELATED APPLICATIONS
  • This application claims the benefit of U.S. Provisional Application Serial No. 60/335,542, filed on Nov. 2, 2001, which is incorporated by reference herein in its entirety.[0001]
  • FIELD OF THE INVENTION
  • The present invention relates to medical information processing systems, and, more particularly to a computerized system and method for selecting persons for clinical trials. [0002]
  • BACKGROUND OF THE INVENTION
  • Selection of persons for clinical trials is an expensive process. It is estimated that it costs drug companies several thousand dollars for each participant selected. Furthermore, sometimes even after being selected, persons must be dropped from a trial because of inaccurate or incorrect information. This may delay the trial, causing an even greater expense. [0003]
  • Although drug companies try to get the word out by placing advertisements or through direct contact with physicians, the selection process is generally quite inefficient. Physicians tend to be busy and do not always have time to respond to requests for patients, and patients may not see the advertisements for clinical trials or subscribe to the periodicals where they are placed. [0004]
  • Moreover, physicians at a specialized medical center tend to refer patients to trials sponsored at that center. Many physicians are unaware of all the available clinical trials because of the time it takes to keep current on all available trials for every patient that the physician sees. [0005]
  • In addition, clinical trials often call for very specific selection criteria and it may be difficult to ascertain if a particular person qualifies for a trial. Furthermore, because hospitals typically store information in an unstructured manner, it may be impossible using hospital records to select patients qualifying for particular clinical trials. [0006]
  • An equally important problem is that of matching clinical trials to specific patients. For example, for cancer alone, at any point in time there are over 600 trials in progress. Statistics show that clinical trial web sites total 75,000 hits every week, mostly from patients seeking information about trials, who are trying to fet added to a trial. Estimates from National Cancer Institute indicate that only two percent of those patients eligible for a trial are in a trial. Thus, it is critically important for an individual to know if he or she may be eligible for a trial. [0007]
  • Given the importance and expense of selecting qualified persons for clinical trials, it would be desirable and highly advantageous to provide improved techniques for automatically selecting prospective participants for clinical trials. [0008]
  • SUMMARY OF THE INVENTION
  • The present invention provides a technique for selecting prospective participants in a clinical trial. [0009]
  • In various embodiments of the present invention, a method is provided that includes receiving a request for a list of prospective participants meeting specified criteria for a clinical trial. A set of patient records is then retrieved to determine persons meeting the specified criteria. [0010]
  • The specified criteria may include probability information, thus allowing the selection of patients likely to meet the specified criteria for the clinical study (e.g., 90% likelihood of diabetes, 70% likelihood of hypertension). In this case, the relevant patient records would include probabilistic information to allow for such selection. Additional information for each prospective participant may also be retrieved. This additional information may include information about other clinical trials that the person participated in, including whether a placebo was administered. [0011]
  • Furthermore, persons may still be selected even though not all information needed to determine whether a person qualifies in all respects for a clinical trial is present. [0012]
  • Consent to participate in a clinical trial should be obtained. A list of persons for whom consent was obtained can be outputted and forwarded to an entity interested in performing the clinical trial. Typically, this is a drug company. Physicians may be notified of their Institutional Review Board (IRB) statuses (e.g., ‘approved’, ‘pending’, or ‘not approved’. Expiration dates of their status may be forwarded to approved physicians. [0013]
  • Because patient confidentiality is important, the anonymity of a person meeting the specified criteria must be preserved. The process of obtaining consent may include selecting physicians associated with the persons meeting the specified criteria, requesting approval to participate from each of the selected physicians, and providing consent information to persons meeting the specified criteria whose physician provided approval to participate in the clinical trial. [0014]
  • To further facilitate the process, questionnaires may be provided. These questionnaires may be used to ascertain qualifications for the clinical trial. [0015]
  • Additionally, compensation and fees can be determined for the parties involved. For example, participating physicians may be compensated. The entity requesting the list may be charged a fee. The patients participating in the clinical trial may also be compensated. [0016]
  • The data source used to determine the persons eligible for the clinical trial may include a data warehouse. Further, it may be populated with structured information obtained from mining unstructured patient records. The patient records may include patient information obtained from a plurality of participating health care providers, such as hospitals. [0017]
  • In various alternative embodiments of the present invention, a system for selecting prospective clinical trials for an individual patient is provided. The system includes a clinical trials database, a data source containing patient information, and a clinical trials brokerage for generating a list of clinical trials for patients meeting specified criteria associated with the clinical trials. At least some of the information in the data source containing patient information may be obtained from mining unstructured patient records. [0018]
  • These and other aspects, features and advantages of the present invention will become apparent from the following detailed description of preferred embodiments, which is to be read in connection with the accompanying drawings.[0019]
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 is a block diagram of a computer processing system to which the present invention may be applied according to an embodiment of the present invention; [0020]
  • FIG. 2 shows an exemplary clinical trials brokerage system according to an embodiment of the present invention; [0021]
  • FIG. 3 shows an exemplary clinical trials brokerage system according to another embodiment of the present invention; and [0022]
  • FIG. 4 shows a flow diagram outlining an exemplary technique for selecting a person for a clinical trial according to an embodiment of the present invention.[0023]
  • DESCRIPTION OF PREFERRED EMBODIMENTS
  • To facilitate a clear understanding of the present invention, illustrative examples are provided herein which describe certain aspects of the invention. However, it is to be appreciated that these illustrations are not meant to limit the scope of the invention, and are provided herein to illustrate certain concepts associated with the invention. [0024]
  • It is also to be understood that the present invention may be implemented in various forms of hardware, software, firmware, special purpose processors, or a combination thereof. Preferably, the present invention is implemented in software as a program tangibly embodied on a program storage device. The program may be uploaded to, and executed by, a machine comprising any suitable architecture. Preferably, the machine is implemented on a computer platform having hardware such as one or more central processing units (CPU), a random access memory (RAM), and input/output (I/O) interface(s). The computer platform also includes an operating system and microinstruction code. The various processes and functions described herein may either be part of the microinstruction code or part of the program (or combination thereof) which is executed via the operating system. In addition, various other peripheral devices may be connected to the computer platform such as an additional data storage device and a printing device. [0025]
  • It is to be understood that, because some of the constituent system components and method steps depicted in the accompanying figures are preferably implemented in software, the actual connections between the system components (or the process steps) may differ depending upon the manner in which the present invention is programmed. [0026]
  • FIG. 1 is a block diagram of a computer processing system [0027] 100 to which the present invention may be applied according to an embodiment of the present invention. The system 100 includes at least one processor (hereinafter processor) 102 operatively coupled to other components via a system bus 104. A read-only memory (ROM) 106, a random access memory (RAM) 108, an I/O interface 110, a network interface 112, and external storage 114 are operatively coupled to the system bus 104. Various peripheral devices such as, for example, a display device, a disk storage device(e.g., a magnetic or optical disk storage device), a keyboard, and a mouse, may be operatively coupled to the system bus 104 by the I/O interface 110 or the network interface 112.
  • The computer system [0028] 100 may be a standalone system or be linked to a network via the network interface 112. The network interface 112 may be a hard-wired interface. However, in various exemplary embodiments, the network interface 112 can include any device suitable to transmit information to and from another device, such as a universal asynchronous receiver/transmitter (UART), a parallel digital interface, a software interface or any combination of known or later developed software and hardware. The network interface may be linked to various types of networks, including a local area network (LAN), a wide area network (WAN), an intranet, a virtual private network (VPN), and the Internet.
  • The external storage [0029] 114 may be implemented using a database management system (DBMS) managed by the processor 102 and residing on a memory such as a hard disk. However, it should be appreciated that the external storage 114 may be implemented on one or more additional computer systems. For example, the external storage 114 may include a data warehouse system residing on a separate computer system.
  • Those skilled in the art will appreciate that other alternative computing environments may be used without departing from the spirit and scope of the present invention. [0030]
  • Referring to FIG. 2, a clinical trials brokerage [0031] 250 is illustrated. The clinical trials brokerage 250 is shown operatively connected to a data repository which contains patient information typically collected from one or more health care organization, such as hospitals. This data repository is called a structured clinical patient record (CPR) 280. In various embodiments of the present invention, a plurality of drug companies, such as drug company 210, request lists of persons meeting specified criteria for clinical trials. The structured CPR 280 is then consulted to obtain the lists of persons meeting the specified criteria.
  • The specified criteria may include probability information, thus allowing the selection of patients likely to meet the specified criteria for the clinical study (e.g., 90% likelihood of diabetes, 70% likelihood of hypertension). In this case, the relevant patient records would include probabilistic information. [0032]
  • Furthermore, persons may still be selected even though not all information needed to determine whether a patient qualifies in all respects for a clinical trial is present. In this case, the list would include “persons of interest” some of whom might later be excluded from participating in the clinical trial for various reasons. Information about each person meeting the selection may additionally be provided, including information about other clinical trials that the person participated in and whether a placebo was administered. [0033]
  • The system may keep track of a plurality of clinical trials, and maintain a list of person who were administered a placebo instead of the drug being tested. In many cases, a person is disqualified from a trial if he or she participated in a trial for a similar drug; however, if it is determined that a placebo was administered, the system may be configured to not exclude the person. In other cases, the system would provide information about the trial(s) that the person participated in. [0034]
  • A physician, such as physician [0035] 230, may be contacted if one of their patients meets the specified criteria for a clinical trial. Prior to releasing information to a drug company, it is generally necessary to obtain agreement of the patient's physician and an informed consent of the patient to participate in the trial. For example, the physician 230 may recommend to a patient that a clinical trial being conducted by the drug company 210 would be beneficial. The details of the trial may have been forwarded to the physician 230. Furthermore, physicians may be notified of their Institutional Review Board (IRB) statuses (e.g., ‘approved’, ‘pending’, or ‘not approved’. Expiration dates of their status may be forwarded to approved physicians.
  • The clinical trials brokerage [0036] 250 can be notified that the patient provided an intent to participate. When the necessary informed consent information is obtained, the clinical trials brokerage 250 can provide the identity of the patient (and other patient information) to the drug company 210.
  • Preferably, the structured CPR [0037] 280 is populated with patient information using data mining techniques described in “Patient Data Mining,” by Rao et al., Attorney Docket No. 2001P20906US01, copending U.S. patent application Ser. No. 10/___,___, filed herewith, which is incorporated by reference herein in its entirety.
  • That disclosure teaches a data mining framework for mining high-quality structured clinical information. The data mining framework includes a data miner that mines medical information from a computerized patient record based on domain-specific knowledge contained in a knowledge base. The data miner includes components for extracting information from the computerized patient record, combining all available evidence in a principled fashion over time, and drawing inferences from this combination process. The mined medical information is stored in a structured computerized patient record. [0038]
  • To determine the specified criteria for the clinical study, multiple data sources typically need to be consulted. For example, to determine whether the patient is diabetic, the system might have to examine the following information: [0039]
  • (a) ICD-9 billing codes for secondary diagnoses associated with diabetes; [0040]
  • (b) drugs administered to the patient that are associated with the treatment of diabetes (e.g., insulin); [0041]
  • (c) patient's lab values that are diagnostic of diabetes (e.g., two successive blood sugar readings over 250 mg/d); [0042]
  • (d) doctor mentions that the patient is a diabetic in the H&P (history & physical) or discharge note (free text); and [0043]
  • (e) patient procedures (e.g., foot exam) associated with being a diabetic. [0044]
  • As can be seen, there are multiple independent sources of information, observations from which can support (with varying degrees of certainty) that the patient is diabetic (or more generally has some disease/condition). Not all of them may be present, and in fact, in some cases, they may contradict each other. Probabilistic observations can be derived, with varying degrees of confidence. Then these observations (e.g., about the billing codes, the drugs, the lab tests, etc.) may be probabilistically combined to come up with a final probability of diabetes. [0045]
  • Note that there may be information in the patient record that contradicts diabetes. For instance, the patient is has some stressful episode (e.g., an operation) and his blood sugar does not go up. [0046]
  • It should be appreciated that the selection of patients for clinical trials may be based on probabilistic information. Thus, a list of patients that meet the specified criteria may comprise a list of patients likely (e.g., according to a particular degree of confidence) to have met the criteria for the clinical trial. [0047]
  • Since it may be necessary to obtain additional information or to verify information about a participant, the clinical trials brokerage [0048] 250 may output, or otherwise provide, questionnaires. These questionnaires may be used to ascertain qualifications for the clinical trial. For example, the patient may be asked to provide a detailed family history of particular diseases.
  • In addition to providing a list of persons meeting the specified criteria, the clinical trials brokerage [0049] 250 may also calculate various charges and fees. For example, participating physicians may need to be compensated. The drug company may be charged a fee for the list. Additionally, participants in the clinical trial may also be compensated.
  • In various embodiments of the present invention, lists of persons who are pre-qualified for certain types of clinical trials may be generated. These lists of pre-qualified individuals may be made available to drug companies or other entities interested in conducting a clinical trial. [0050]
  • Referring to FIG. 3, an alternate embodiment of the present invention is illustrated. In this embodiment, a clinical trials brokerage [0051] 350 is able to access a structured CPR 380 containing mined structured patient information, and also a clinical trials database 390 containing information about various clinical trials. The information in the clinical trials database 390 may include information regarding the qualifications for clinical trials along with other information regarding the trials. A patient, such as patient 335, may request information about a particular clinical trial. The patient may either directly access the clinical trials brokerage 350 or go through a physician, such as physician 330. The clinical trials brokerage 330 may access the structured CPR 380 (populated with information in the same manner as the CPR 280) to retrieve information about the patient, and attempt to match clinical trials of interest to the patient based on the medical history of the patient and available trials.
  • Referring to FIG. 4, a flow diagram outlining an exemplary technique for selecting a person for a clinical trial is illustrated. Beginning at step [0052] 401, a person is selected from among a set of persons meeting specified criteria. This step may include receiving a request for a list of persons meeting specified criteria for a clinical trial, and retrieving a set of patient records from a data source to determine persons meeting the specified criteria.
  • For example, a drug company might be interested in selecting black males who are diabetic and have had a heart attack within the last three years. This might be used to test a new drug. [0053]
  • Using conventional approaches, satisfying the above-mentioned selection criteria could be difficult because computerized hospital databases generally do not store such information. However, by employing the data mining techniques described in “Patient Data Mining,” by Rao et al., Attorney Docket No. 2001P20906US01, copending U.S. patent application Ser. No. 10/___,___, filed herewith, a structured CPR can be populated with such patient information, thus allowing this selection criteria to be satisfied. [0054]
  • In step [0055] 402, the person's physician can be notified that the person has been selected for the clinical trial. At this point, a hospital's Institutional Review Board (IRB) can also be notified. The physician can also be notified if IRB approval has already been granted for this trial at this site, or if he needs to wait for the IRB approval for this trial. Next, in step 403, a determination is made as to whether the physician will participate in the study. If it is determined that the physician will participate, control continues to step 404; otherwise control terminates at step 408.
  • In step [0056] 404, the person is notified that he or she may qualify for the clinical trial. The patient can be directly contacted, or, indirectly contacted through a physician. At this point, the patient may be given detailed information about the clinical trial. The patient may be asked for additional information, such as through a questionnaire. The questionnaire may be used to determine qualification for the study and/or as a way to obtain additional useful information.
  • Next, in step [0057] 405, a determination is made as to whether the person indicated a desire to participate in the clinical trial. If the person notified his or her physician of an intent to participate, control continues to step 406; otherwise control terminates at step 408.
  • In step [0058] 406, release information is obtained. At this point the person may be provided with a consent form or be directed to complete one provided to him by his or her physician. Any information regarding participant compensation, including reimbursements, may also be provided. Control continues to step 407.
  • In step [0059] 407, fees and charges may be determined. For instance, the entity requesting the list of patients may be charged an appropriate fee for the list of patients. Furthermore, the physician and trial participants may also be compensated for their participation in the study. Control continues to step 408 where the operation stops.
  • As shown in FIGS. [0060] 1-4, this invention is preferably implemented using a general purpose computer system. However the systems and methods of this invention can be implemented using any combination of one or more programmed general purpose computers, programmed microprocessors or micro-controllers and peripheral integrated circuit elements, ASIC or other integrated circuits, digital signal processors, hardwired electronic or logic circuits such as discrete element circuits, programmable logic devices such as a PLD, PLA, FPGA or PAL, or the like. In general, any device capable of implementing a finite state machine that is in turn capable of implementing the flowchart shown in FIG. 4 can be used to implement this system.
  • Although illustrative embodiments of the present invention have been described herein with reference to the accompanying drawings, it is to be understood that the invention is not limited to those precise embodiments, and that various other changes and modifications may be affected therein by one skilled in the art without departing from the scope or spirit of the invention. [0061]

Claims (37)

    What is claimed is:
  1. 1. A system for selecting prospective participants in a clinical trial, comprising:
    a data source containing patient information, at least some of the patient information obtained from mining unstructured patient records; and
    a clinical trials brokerage for retrieving a set of patient records from the data source and generating a list of persons who meet specified criteria associated with the clinical trial.
  2. 2. The system of claim 1, wherein the clinical trials brokerage is configured to obtain consent from one or more the person meeting the specified criteria.
  3. 3. The system of claim 1, wherein the list of persons meeting the specified criteria is requested from an entity interested in performing the clinical trial.
  4. 4. The system of claim 1, wherein the anonymity of the persons meeting the specified criteria is preserved until consent is provided.
  5. 5. The system of claim 1, wherein the list of persons meeting specified criteria includes persons pre-qualified for the clinical trial.
  6. 6. The system of claim 1, wherein the data source includes information collected from a plurality of hospitals.
  7. 7. The system of claim 1, wherein the specified criteria includes probability criteria.
  8. 8. The system of claim 1, wherein the obtained patient records include probabilistic information.
  9. 9. The system of claim 1, wherein information needed to determine whether a patient qualifies in all respects is not included in the obtained patient records.
  10. 10. The system of claim 1, wherein information about each person in the list is provided.
  11. 11. The system of claim 10, wherein the information includes information regarding previous clinical trials that the person participated in.
  12. 12. A method for selecting prospective participants in a clinical trial, comprising the steps of:
    receiving a request for a list of persons meeting specified criteria associated with a clinical trial; and
    retrieving a set of patient records from a data source to determine persons meeting the specified criteria.
  13. 13. The method of claim 12, further comprising the steps of:
    obtaining consent to participate in the clinical trial from one or more of the persons meeting the specified criteria; and
    outputting a list of persons from whom consent was obtained.
  14. 14. The method of claim 13, further including the step of forwarding the list of persons to an entity interested in performing the clinical trial.
  15. 15. The method of claim 13, wherein the step of obtaining consent comprises the steps of:
    selecting physicians associated with the persons meeting the specified criteria;
    requesting approval to participate from each of the selected physicians; and
    providing consent information to persons meeting the specified criteria if their physician provided approval to participate in the clinical trial.
  16. 16. The method of claim 13, wherein obtaining consent includes notifying physicians of their Institutional Review Board (IRB) statuses.
  17. 17. The method of claim 16, wherein obtaining consent further includes forwarding to accepted status physicians expiration dates of their IRB approvals.
  18. 18. The method of claim 14, wherein the request for the list of persons is received from the entity interested in performing the clinical trial.
  19. 19. The method of claim 12, wherein the anonymity of the persons meeting the specified criteria is preserved until consent is provided.
  20. 20. The method of claim 12, further comprising the step of providing questionnaires.
  21. 21. The method of claim 20, wherein the questionnaires are used to ascertain qualification for the clinical trial.
  22. 22. The method of claim 14, wherein the entity requesting the list of patients is charged a fee for the list of patients.
  23. 23. The method of claim 14, wherein persons participating in the clinical trial are compensated.
  24. 24. The method of claim 15, wherein a participating physician is compensated.
  25. 25. The method of claim 12, wherein the data source is a data warehouse.
  26. 26. The method of claim 25, wherein the data warehouse is populated with structured patient information obtained from mining unstructured patient records.
  27. 27. The method of claim 12, wherein the request is received from a drug company.
  28. 28. The method of claim 12, wherein the data source includes information collected from a plurality of hospitals.
  29. 29. The method of claim 12, wherein the specified criteria includes a probability value.
  30. 30. The method of claim 29, wherein the probability value includes a confidence interval.
  31. 31. The method of claim 12, wherein the obtained patient records include probabilistic information.
  32. 32. The method of claim 12, wherein information needed to determine whether a patient qualifies in all respects is not included in the obtained patient records.
  33. 33. The method of claim 12, wherein information about each person in the list is generated.
  34. 34. The method of claim 12, wherein the information includes information regarding previous clinical trials that the person participated in.
  35. 33. A program storage device readable by a machine, tangibly embodying a program of instructions executable on the machine to perform method steps for selecting prospective participants in a clinical trial, the method steps comprising:
    receiving a request for a list of persons meeting specified criteria associated with a clinical trial; and
    retrieving a set of patient records from a data source to determine persons meeting the specified criteria.
  36. 34. A system for selecting prospective clinical trials for an individual patient, comprising:
    a clinical trials database;
    a data source containing patient information; and
    a clinical trials brokerage for generating a list of clinical trials for patients meeting specified criteria associated with the clinical trials.
  37. 35. The system of claim 34, wherein at least some of the information in the data source containing patient information is obtained from mining unstructured patient records.
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US10287085 Active 2025-12-23 US7744540B2 (en) 2001-11-02 2002-11-04 Patient data mining for cardiology screening
US10287329 Active 2028-03-28 US8626533B2 (en) 2001-11-02 2002-11-04 Patient data mining with population-based analysis
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US10287075 Active 2028-01-07 US8214225B2 (en) 2001-11-02 2002-11-04 Patient data mining, presentation, exploration, and verification
US10287074 Active 2028-11-01 US8214224B2 (en) 2001-11-02 2002-11-04 Patient data mining for quality adherence
US10287098 Abandoned US20030130871A1 (en) 2001-11-02 2002-11-04 Patient data mining for clinical trials
US10287053 Active 2025-04-21 US7181375B2 (en) 2001-11-02 2002-11-04 Patient data mining for diagnosis and projections of patient states
US11077728 Abandoned US20050159654A1 (en) 2001-11-02 2005-03-11 Patient data mining for clinical trials
US12488083 Active 2024-01-24 US8949079B2 (en) 2001-11-02 2009-06-19 Patient data mining
US12780012 Active 2023-01-07 US8280750B2 (en) 2001-11-02 2010-05-14 Patient data mining for cardiology screening
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US10287085 Active 2025-12-23 US7744540B2 (en) 2001-11-02 2002-11-04 Patient data mining for cardiology screening
US10287329 Active 2028-03-28 US8626533B2 (en) 2001-11-02 2002-11-04 Patient data mining with population-based analysis
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Cited By (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030120458A1 (en) * 2001-11-02 2003-06-26 Rao R. Bharat Patient data mining
US20040083217A1 (en) * 2002-10-25 2004-04-29 Cameron Brackett Method, system, and computer product for collecting and distributing clinical data for data mining
US20040093238A1 (en) * 2002-11-08 2004-05-13 Deakter Daniel R. System and process for matching patients with clinical medical trials
US20040147840A1 (en) * 2002-11-08 2004-07-29 Bhavani Duggirala Computer aided diagnostic assistance for medical imaging
US20040172293A1 (en) * 2003-01-21 2004-09-02 Paul Bruschi Method for identifying and communicating with potential clinical trial participants
US20050086074A1 (en) * 2003-10-15 2005-04-21 Medical Web Technologies, Inc. Method and apparatus for sharing healthcare data
US20050192842A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for authorizing and processing reimbursements for services provided in the collection of implantable medical device data
US20050192843A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for validating patient and medical devices information
US20050192836A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for delivering and gathering medical diagnostic data
WO2005081084A2 (en) * 2004-02-18 2005-09-01 Siemens Aktiengesellschaft Method for selecting a potential participant for a medical study on the basis of a selection criterion
US20050192649A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for providing variable medical information
US20050192844A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for automatically collecting, formatting, and storing medical device data in a database
US20050192838A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for accessing and distributing medical information
US20060184475A1 (en) * 2005-02-16 2006-08-17 Sriram Krishnan Missing data approaches in medical decision support systems
WO2006096364A2 (en) 2005-03-03 2006-09-14 Siemens Medical Solutions Usa, Inc. Performance adjustments in medical decision support systems
US20060265253A1 (en) * 2005-05-18 2006-11-23 Rao R B Patient data mining improvements
US20070067189A1 (en) * 2005-09-16 2007-03-22 Numoda Corporation Method and apparatus for screening, enrollment and management of patients in clinical trials
US20070094188A1 (en) * 2005-08-25 2007-04-26 Pandya Abhinay M Medical ontologies for computer assisted clinical decision support
US20070106531A1 (en) * 2002-11-08 2007-05-10 Daniel Deakter Method and process that automatically finds patients for clinical drug or device trials
US20070150372A1 (en) * 2005-12-19 2007-06-28 Roy Schoenberg Vendor and Consumer Matching
WO2007079442A1 (en) * 2006-01-03 2007-07-12 Invivodata, Inc. Apparatus and method for prediction and management of participant compliance in clinical research
US20070168345A1 (en) * 2006-01-17 2007-07-19 Andrew Gibbs System and method of identifying subject matter experts
US20070250347A1 (en) * 2006-04-25 2007-10-25 Klaus Abraham-Fuchs Broker service and system architecture for health care data
US20070255584A1 (en) * 2003-09-08 2007-11-01 Pavlatos Christ J Patient Physician Connectivity System and Method
US20070276777A1 (en) * 2006-04-17 2007-11-29 Siemens Medical Solutions Usa, Inc. Personalized Prognosis Modeling In Medical Treatment Planning
US20080033894A1 (en) * 2006-04-17 2008-02-07 Siemens Medical Solutions Usa, Inc. Prognosis Modeling From One or More Sources of Information
US20080059391A1 (en) * 2006-09-06 2008-03-06 Siemens Medical Solutions Usa, Inc. Learning Or Inferring Medical Concepts From Medical Transcripts
US20080114616A1 (en) * 2006-11-10 2008-05-15 General Electric Company Method and system for clinical trial compliance
US20080195600A1 (en) * 2006-05-25 2008-08-14 Deakter Daniel R Efficient method and process to search structured and unstructured patient data to match patients to clinical drug/device trials
US20080201280A1 (en) * 2007-02-16 2008-08-21 Huber Martin Medical ontologies for machine learning and decision support
US20080228769A1 (en) * 2007-03-15 2008-09-18 Siemens Medical Solutions Usa, Inc. Medical Entity Extraction From Patient Data
US20090076851A1 (en) * 2001-12-14 2009-03-19 Siemens Medical Solutions Usa, Inc. Early detection of disease outbreak using electronic patient data to reduce public health threat from bio-terrorism
US20090313045A1 (en) * 2008-06-11 2009-12-17 Boyce Mark D System and Method for Medical Research and Clinical Trial
US20100169115A1 (en) * 2008-12-31 2010-07-01 Tamis Robert H System for matching individuals with health care providers and methods thereof
US20100235378A1 (en) * 2006-08-22 2010-09-16 Lead Horse Technologies, Inc. Medical assessment support system and method
US20110078145A1 (en) * 2009-09-29 2011-03-31 Siemens Medical Solutions Usa Inc. Automated Patient/Document Identification and Categorization For Medical Data
US20110184761A1 (en) * 2010-01-25 2011-07-28 Siemens Medical Solutions Usa, Inc. Method and Apparatus for Estimating Patient Populations
US20110231422A1 (en) * 2005-12-06 2011-09-22 Ingenix Inc. Analyzing administrative healthcare claims data and other data sources
US20110238438A1 (en) * 2010-03-25 2011-09-29 Numoda Technologies, Inc. Automated method of graphically displaying predicted patient enrollment in a clinical trial study
US20120316898A1 (en) * 2011-06-08 2012-12-13 Levitt Tod S Scalable determination of probable patient eligibility for clinical trials and associated process for active solicitation of patients for clinical trials via their healthcare providers
US20130318049A1 (en) * 2012-05-23 2013-11-28 Oracle International Corporation Partial source verification of edc data
US8620677B2 (en) 2002-04-09 2013-12-31 Pcrs, Inc. Online, interactive evaluation of research performance
US8670997B2 (en) 2006-02-09 2014-03-11 Siemens Medical Solutions Usa, Inc. Quality metric extraction and editing for medical data
US8682693B2 (en) 2002-09-09 2014-03-25 Siemens Medical Solutions Usa, Inc. Patient data mining for lung cancer screening
US20140122113A1 (en) * 2012-06-06 2014-05-01 Cerner Innovation, Inc. Providing indications of clinical-trial criteria modifications
US8949082B2 (en) 2001-11-02 2015-02-03 Siemens Medical Solutions Usa, Inc. Healthcare information technology system for predicting or preventing readmissions
US9129054B2 (en) 2012-09-17 2015-09-08 DePuy Synthes Products, Inc. Systems and methods for surgical and interventional planning, support, post-operative follow-up, and, functional recovery tracking
WO2015139115A1 (en) * 2014-03-17 2015-09-24 Eqol Inc. System and method for managing illness outside of a hospital environment
US9747654B2 (en) 2014-12-09 2017-08-29 Cerner Innovation, Inc. Virtual home safety assessment framework
JP6262908B1 (en) * 2017-06-09 2018-01-17 リーズンホワイ株式会社 Medical system and medical program

Families Citing this family (213)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6206829B1 (en) 1996-07-12 2001-03-27 First Opinion Corporation Computerized medical diagnostic and treatment advice system including network access
US5660176A (en) 1993-12-29 1997-08-26 First Opinion Corporation Computerized medical diagnostic and treatment advice system
USRE43433E1 (en) 1993-12-29 2012-05-29 Clinical Decision Support, Llc Computerized medical diagnostic and treatment advice system
US5935060A (en) 1996-07-12 1999-08-10 First Opinion Corporation Computerized medical diagnostic and treatment advice system including list based processing
WO1998040835A1 (en) 1997-03-13 1998-09-17 First Opinion Corporation Disease management system
CA2398823A1 (en) 2000-02-14 2001-08-23 First Opinion Corporation Automated diagnostic system and method
DE10140329A1 (en) * 2001-08-16 2003-03-06 Siemens Ag Testing of whether the treatment of a patient in a health organization corresponds to that of a treatment code assigned to the patient using a computer based knowledge system and associated plausibility testing
US8649843B2 (en) * 2001-11-24 2014-02-11 Ben A. Arnold Automated calcium scoring of the aorta
EP1451753A2 (en) * 2001-11-24 2004-09-01 Image Analysis, Inc. Automatic detection and quantification of coronary and aortic calcium
US20060259329A1 (en) * 2002-04-09 2006-11-16 Charlotte-Mecklenburg Hospital Authority D/B/A Carolinas Medical Center System and Method for Determining the Degree of Abnormality of a Patient's Vital Signs
US8560582B2 (en) 2002-08-12 2013-10-15 Jeffrey Saul Harris Method for analyzing records in a data base
US20040186357A1 (en) * 2002-08-20 2004-09-23 Welch Allyn, Inc. Diagnostic instrument workstation
US20050288571A1 (en) 2002-08-20 2005-12-29 Welch Allyn, Inc. Mobile medical workstation
KR100612146B1 (en) * 2002-10-01 2006-08-14 학교법인연세대학교 Liver Cancer Forecasting System For Early Diagnosis and Control Method Thereof
US20040167908A1 (en) * 2002-12-06 2004-08-26 Attensity Corporation Integration of structured data with free text for data mining
WO2004089184A3 (en) * 2003-04-01 2005-06-09 Diadexus Inc NEW USES OF Lp-PLA2 IN COMBINATION TO ASSESS CORONARY RISK
US20040215656A1 (en) * 2003-04-25 2004-10-28 Marcus Dill Automated data mining runs
US7780595B2 (en) 2003-05-15 2010-08-24 Clinical Decision Support, Llc Panel diagnostic method and system
CN1839391A (en) * 2003-06-25 2006-09-27 美国西门子医疗解决公司 Systems and methods for automated diagnosis and decision support for breast imaging
US7653227B2 (en) * 2004-02-09 2010-01-26 Siemens Medical Solutions Usa, Inc. Hierarchical modeling in medical abnormality detection
US7912528B2 (en) * 2003-06-25 2011-03-22 Siemens Medical Solutions Usa, Inc. Systems and methods for automated diagnosis and decision support for heart related diseases and conditions
CN1567303A (en) * 2003-07-03 2005-01-19 富士通株式会社 Method and apparatus for automatic division of structure document information block
US20050021489A1 (en) * 2003-07-22 2005-01-27 Microsoft Corporation Data mining structure
CN1836240A (en) * 2003-08-13 2006-09-20 美国西门子医疗解决公司 CAD (computer-aided decision ) support systems and methods
US8412541B2 (en) 2003-08-14 2013-04-02 Edda Technology, Inc. Method and system for intelligent qualitative and quantitative analysis for medical diagnosis
US8275631B2 (en) 2003-09-15 2012-09-25 Idx Systems Corporation Executing clinical practice guidelines
US20050071462A1 (en) * 2003-09-30 2005-03-31 Ibm Corporation Creating user metric patterns
WO2005036446A3 (en) * 2003-10-07 2005-10-27 Alex L Bangs Simulating patient-specific outcomes
EP1687733A4 (en) * 2003-10-29 2011-06-08 Patientrack Pty Ltd System and process for facilitating the provision of health care
US20060020215A1 (en) * 2003-11-06 2006-01-26 Callahan Alfred S Iii Systems and methods for health screening for vascular disease
US7152785B2 (en) * 2003-12-09 2006-12-26 Ge Medical Systems Global Technology Company, Llc Patient-centric data acquisition protocol selection and identification tags therefor
US7376644B2 (en) * 2004-02-02 2008-05-20 Ram Consulting Inc. Knowledge portal for accessing, analyzing and standardizing data
US20070142979A1 (en) * 2004-02-18 2007-06-21 Klaus Abraham-Fuchs Method for the selection of a participant in a medical project with selection criteria for patients
US20050182665A1 (en) * 2004-02-18 2005-08-18 Klaus Abraham-Fuchs Method of recruiting patients for a clinical study
US7976539B2 (en) 2004-03-05 2011-07-12 Hansen Medical, Inc. System and method for denaturing and fixing collagenous tissue
US20060100610A1 (en) 2004-03-05 2006-05-11 Wallace Daniel T Methods using a robotic catheter system
US20050203776A1 (en) * 2004-03-15 2005-09-15 Godwin Sharen A. Method of identifying clinical trial participants
US8155977B2 (en) * 2004-04-15 2012-04-10 The Trizetto Group, Inc. Rule management method and system
US7306562B1 (en) 2004-04-23 2007-12-11 Medical Software, Llc Medical risk assessment method and program product
US7949545B1 (en) 2004-05-03 2011-05-24 The Medical RecordBank, Inc. Method and apparatus for providing a centralized medical record system
US20060074320A1 (en) * 2004-08-27 2006-04-06 Yoo Yang M Home ultrasound system
NL1027047C2 (en) * 2004-09-15 2006-03-16 Roderik Adriaan Kraaijenhagen Computer apparatus for determining a diagnosis.
WO2006034366A1 (en) * 2004-09-21 2006-03-30 Siemens Medical Solutions Usa, Inc. Hierarchical medical image view determination
US20060074315A1 (en) * 2004-10-04 2006-04-06 Jianming Liang Medical diagnostic ultrasound characterization of cardiac motion
US20060074312A1 (en) * 2004-10-06 2006-04-06 Bogdan Georgescu Medical diagnostic ultrasound signal extraction
US20060101072A1 (en) * 2004-10-21 2006-05-11 International Business Machines Corproation System and method for interpreting scan data
US9081879B2 (en) 2004-10-22 2015-07-14 Clinical Decision Support, Llc Matrix interface for medical diagnostic and treatment advice system and method
US20060101075A1 (en) * 2004-11-10 2006-05-11 Peter Lehel Method and system for prospectively acquiring ROI based data for retrospective re-analysis
US20060136259A1 (en) * 2004-12-17 2006-06-22 General Electric Company Multi-dimensional analysis of medical data
JP4797380B2 (en) * 2004-12-28 2011-10-19 コニカミノルタホールディングス株式会社 Medical support system
US20060247544A1 (en) * 2005-02-03 2006-11-02 Maleeha Qazi Characterization of cardiac motion with spatial relationship
US8812433B2 (en) * 2005-02-07 2014-08-19 Mimosa Systems, Inc. Dynamic bulk-to-brick transformation of data
CA2620134A1 (en) * 2005-08-23 2007-03-01 Mimosa Systems, Inc. Enterprise service availability through identity preservation
US7870416B2 (en) * 2005-02-07 2011-01-11 Mimosa Systems, Inc. Enterprise service availability through identity preservation
US7778976B2 (en) 2005-02-07 2010-08-17 Mimosa, Inc. Multi-dimensional surrogates for data management
US7917475B2 (en) * 2005-02-07 2011-03-29 Mimosa Systems, Inc. Enterprise server version migration through identity preservation
US8918366B2 (en) * 2005-02-07 2014-12-23 Mimosa Systems, Inc. Synthetic full copies of data and dynamic bulk-to-brick transformation
US8271436B2 (en) * 2005-02-07 2012-09-18 Mimosa Systems, Inc. Retro-fitting synthetic full copies of data
US8161318B2 (en) * 2005-02-07 2012-04-17 Mimosa Systems, Inc. Enterprise service availability through identity preservation
US7657780B2 (en) 2005-02-07 2010-02-02 Mimosa Systems, Inc. Enterprise service availability through identity preservation
US8799206B2 (en) * 2005-02-07 2014-08-05 Mimosa Systems, Inc. Dynamic bulk-to-brick transformation of data
US8543542B2 (en) * 2005-02-07 2013-09-24 Mimosa Systems, Inc. Synthetic full copies of data and dynamic bulk-to-brick transformation
DE102005008386A1 (en) * 2005-02-23 2006-08-24 Siemens Ag Patient health preventive monitoring procedure has body position, movement or environmental sensors with processor using data mining and decision techniques to make recommendations
US7657521B2 (en) * 2005-04-15 2010-02-02 General Electric Company System and method for parsing medical data
US20090049104A1 (en) * 2005-06-08 2009-02-19 William Pan Method and system for configuring a variety of medical information
US7849048B2 (en) 2005-07-05 2010-12-07 Clarabridge, Inc. System and method of making unstructured data available to structured data analysis tools
US7849049B2 (en) 2005-07-05 2010-12-07 Clarabridge, Inc. Schema and ETL tools for structured and unstructured data
JP4619219B2 (en) * 2005-07-19 2011-01-26 株式会社エヌ・ティ・ティ・データ Subject selecting apparatus
US7685000B1 (en) * 2005-08-10 2010-03-23 Matria Healthcare, Inc. Predictive modeling system and method for disease management
US20070156720A1 (en) * 2005-08-31 2007-07-05 Eagleforce Associates System for hypothesis generation
US7624098B2 (en) * 2005-10-07 2009-11-24 International Business Machines Corporation Generating suitable data for statistical analysis
US20100278405A1 (en) * 2005-11-11 2010-11-04 Kakadiaris Ioannis A Scoring Method for Imaging-Based Detection of Vulnerable Patients
US20070118399A1 (en) * 2005-11-22 2007-05-24 Avinash Gopal B System and method for integrated learning and understanding of healthcare informatics
US20070120640A1 (en) * 2005-11-28 2007-05-31 Han-Ming Lee Plug with overload protection and a safety switch
EP1808790A1 (en) * 2005-12-15 2007-07-18 Statlife Method of determining risk scores
JP2009528103A (en) * 2006-03-03 2009-08-06 メンティス キュラ イーエイチエフ. Creating a reference tool and method and apparatus for generating an identification signal indicating a medical condition of a subject by using
US7593927B2 (en) * 2006-03-10 2009-09-22 Microsoft Corporation Unstructured data in a mining model language
US20100081941A1 (en) * 2006-03-22 2010-04-01 Endothelix, Inc. Cardiovascular health station methods and apparatus
US8920343B2 (en) 2006-03-23 2014-12-30 Michael Edward Sabatino Apparatus for acquiring and processing of physiological auditory signals
WO2007120904A3 (en) * 2006-04-14 2008-12-04 Fuzzmed Inc System, method, and device for personal medical care, intelligent analysis, and diagnosis
US20070255704A1 (en) * 2006-04-26 2007-11-01 Baek Ock K Method and system of de-identification of a record
FR2901042B1 (en) * 2006-05-15 2008-08-22 Clinigrid Sarl System and related data management process for a patient as part of an operation of evaluation
JP4960024B2 (en) * 2006-06-07 2012-06-27 オリンパスメディカルシステムズ株式会社 Medical image management method and a medical image management apparatus using the same
US20070294112A1 (en) * 2006-06-14 2007-12-20 General Electric Company Systems and methods for identification and/or evaluation of potential safety concerns associated with a medical therapy
US20070294113A1 (en) * 2006-06-14 2007-12-20 General Electric Company Method for evaluating correlations between structured and normalized information on genetic variations between humans and their personal clinical patient data from electronic medical patient records
US20080126130A1 (en) * 2006-07-17 2008-05-29 Walgreen Co. Compliance With A Medication Therapy Regimen
US8478605B2 (en) * 2006-07-17 2013-07-02 Walgreen Co. Appropriateness of a medication therapy regimen
US8700430B2 (en) * 2006-07-17 2014-04-15 Walgreen Co. Optimization of a medication therapy regimen
US20080015893A1 (en) * 2006-07-17 2008-01-17 Walgreen Co. Identification of Inappropriate Medications In A Medication Therapy Regimen
JP4997892B2 (en) * 2006-09-19 2012-08-08 富士ゼロックス株式会社 Search system, search method and search program
US7558416B2 (en) 2006-10-02 2009-07-07 Johnson & Johnson Consumer Companies, Inc. Apparatus and method for measuring photodamage to skin
US20080126167A1 (en) * 2006-10-24 2008-05-29 Mid-America Consulting Group Invitee-participant matching system for meeting scheduling
WO2008133715A3 (en) * 2006-11-03 2009-01-15 Air Prod & Chem System and method for process monitoring
US20080140371A1 (en) * 2006-11-15 2008-06-12 General Electric Company System and method for treating a patient
US20080133275A1 (en) * 2006-11-28 2008-06-05 Ihc Intellectual Asset Management, Llc Systems and methods for exploiting missing clinical data
US8200506B2 (en) * 2006-12-19 2012-06-12 Accenture Global Services Limited Integrated health management platform
US20080154642A1 (en) * 2006-12-21 2008-06-26 Susan Marble Healthcare Core Measure Tracking Software and Database
US8566727B2 (en) * 2007-01-03 2013-10-22 General Electric Company Method and system for automating a user interface
US8140352B2 (en) * 2007-01-03 2012-03-20 Performance Clinical Systems, Llc Order sets having different views for CPOE systems
US20080201429A1 (en) * 2007-02-16 2008-08-21 Siemens Medical Solutions Usa, Inc. System Supporting Live Electronic Messaging Communication Between A Healthcare Worker And A Patient
US20080208624A1 (en) * 2007-02-22 2008-08-28 General Electric Company Methods and systems for providing clinical display and search of electronic medical record data from a variety of information systems
JP4640845B2 (en) * 2007-03-05 2011-03-02 富士フイルム株式会社 Image processing apparatus and its program
US8031920B2 (en) * 2007-03-09 2011-10-04 Cerner Innovation, Inc. System and method for associating electronic images in the healthcare environment
US7936908B2 (en) * 2007-03-09 2011-05-03 Cerner Innovation, Inc. Graphical user interface for displaying a radiology image for a patient and an associated laboratory report summary
US20080221929A1 (en) * 2007-03-09 2008-09-11 Cerner Innovation, Inc. System and method for associating a patient specimen identifier with a radiology image for the patient
US20080228522A1 (en) * 2007-03-12 2008-09-18 General Electric Company Enterprise medical imaging and information management system with clinical data mining capabilities and method of use
US20110124975A1 (en) * 2007-03-16 2011-05-26 Arthur Solomon Thompson Method for Medical Diagnosis Utilizing PDA Software Robots
RU2512072C2 (en) * 2007-04-13 2014-04-10 Конинклейке Филипс Электроникс, Н.В. Correlation of clinical events
US7873414B2 (en) * 2007-04-17 2011-01-18 Cardiac Pacemakers, Inc. Patient characteristic based adaptive anti-tachy pacing programming
US20080270180A1 (en) * 2007-04-30 2008-10-30 Intuit Inc. Method and system for health care data transfer
US8571883B2 (en) * 2007-05-10 2013-10-29 Eveready Battery Company, Inc. Image analysis processes and methods for the evaluation of tampon performance
US20090055217A1 (en) * 2007-08-23 2009-02-26 Grichnik Anthony J Method and system for identifying and communicating a health risk
US8260636B2 (en) * 2007-08-31 2012-09-04 Caterpillar Inc. Method and system for prioritizing communication of a health risk
US20090070137A1 (en) * 2007-09-10 2009-03-12 Sultan Haider Method and system to optimize quality of patient care paths
US20090070146A1 (en) * 2007-09-10 2009-03-12 Sultan Haider Method for managing the release of data
US20090187425A1 (en) * 2007-09-17 2009-07-23 Arthur Solomon Thompson PDA software robots leveraging past history in seconds with software robots
US7890351B2 (en) * 2007-10-02 2011-02-15 American Well Corporation Managing utilization
JP5159242B2 (en) 2007-10-18 2013-03-06 キヤノン株式会社 Diagnosis support apparatus, a control method of the diagnosis support apparatus, and program
US20090254371A1 (en) * 2007-12-05 2009-10-08 Bartholomew Iii Samuel W Quality Assurance Methods for Medication Therapy Management
JP2011508301A (en) 2007-12-21 2011-03-10 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Semi-automatic evaluation of the continuous version of the clinical decision support system
EP2229643A1 (en) * 2007-12-28 2010-09-22 Koninklijke Philips Electronics N.V. Retrieval of similar patient cases based on disease probability vectors
US8812240B2 (en) * 2008-03-13 2014-08-19 Siemens Medical Solutions Usa, Inc. Dose distribution modeling by region from functional imaging
US8032308B2 (en) * 2008-03-13 2011-10-04 Siemens Medical Solutions Usa, Inc. Modeling lung cancer survival probability after or side-effects from therapy
US20090254376A1 (en) * 2008-04-08 2009-10-08 The Quantum Group, Inc. Dynamic integration of disparate health-related processes and data
US8412542B2 (en) * 2008-04-25 2013-04-02 Peoplechart Corporation Scoring system for monitoring or measuring adherence in medical treatment
US20100010320A1 (en) * 2008-07-07 2010-01-14 Perkins David G Mobile medical workstation and a temporarily associating mobile computing device
US20100017231A1 (en) * 2008-07-17 2010-01-21 Archie Galbraith Active Patient Management
US8078554B2 (en) 2008-09-03 2011-12-13 Siemens Medical Solutions Usa, Inc. Knowledge-based interpretable predictive model for survival analysis
US20110202486A1 (en) * 2009-07-21 2011-08-18 Glenn Fung Healthcare Information Technology System for Predicting Development of Cardiovascular Conditions
RU2533500C2 (en) * 2008-09-26 2014-11-20 Конинклейке Филипс Электроникс, Н.В. System and method for combining clinical signs and image signs for computer-aided diagnostics
US9123095B2 (en) * 2008-09-29 2015-09-01 Koninklijke Philips N.V. Method for increasing the robustness of computer-aided diagnosis to image processing uncertainties
US20100082506A1 (en) * 2008-09-30 2010-04-01 General Electric Company Active Electronic Medical Record Based Support System Using Learning Machines
US20100082371A1 (en) * 2008-10-01 2010-04-01 General Electric Company, A New York Corporation Patient Document Privacy And Disclosure Engine
US20110173027A1 (en) * 2008-10-10 2011-07-14 Koninklijke Philips Electronics N.V. Health-risk metric determination and/or presentation
US8649577B1 (en) 2008-11-30 2014-02-11 Image Analysis, Inc. Automatic method and system for measurements of bone density and structure of the hip from 3-D X-ray imaging devices
US8560346B2 (en) 2009-01-05 2013-10-15 Siemens Medical Solutions Usa, Inc. System and method for ranking quality improvement factors in patient care
US8126736B2 (en) 2009-01-23 2012-02-28 Warsaw Orthopedic, Inc. Methods and systems for diagnosing, treating, or tracking spinal disorders
US8685093B2 (en) 2009-01-23 2014-04-01 Warsaw Orthopedic, Inc. Methods and systems for diagnosing, treating, or tracking spinal disorders
US8250026B2 (en) 2009-03-06 2012-08-21 Peoplechart Corporation Combining medical information captured in structured and unstructured data formats for use or display in a user application, interface, or view
WO2010108092A3 (en) * 2009-03-19 2011-01-13 Phenotypeit, Inc. Medical health information system
CA2756717A1 (en) * 2009-03-24 2010-09-30 Performance Clinical Systems, Llc Method for selecting custom order hospitalization sets
US8346369B2 (en) * 2009-05-14 2013-01-01 Cardiac Pacemakers, Inc. Systems and methods for programming implantable medical devices
US20110010195A1 (en) * 2009-07-08 2011-01-13 Steven Charles Cohn Medical history system
US20110022981A1 (en) * 2009-07-23 2011-01-27 Deepa Mahajan Presentation of device utilization and outcome from a patient management system
US8139822B2 (en) * 2009-08-28 2012-03-20 Allen Joseph Selner Designation of a characteristic of a physical capability by motion analysis, systems and methods
US20110054289A1 (en) * 2009-09-01 2011-03-03 Adidas AG, World of Sports Physiologic Database And System For Population Modeling And Method of Population Modeling
US20110077972A1 (en) * 2009-09-24 2011-03-31 Agneta Breitenstein Systems and methods of clinical tracking
EP2480129A4 (en) * 2009-09-25 2016-03-23 Volcano Corp Device and method for determining the likelihood of a patient having a clinical event or a clinically silent event based on ascertained physiological parameters
US8930389B2 (en) * 2009-10-06 2015-01-06 International Business Machines Corporation Mutual search and alert between structured and unstructured data stores
US20110106558A1 (en) * 2009-11-02 2011-05-05 Cerner Innovation, Inc. Infection control solution
WO2011070462A2 (en) * 2009-12-10 2011-06-16 Koninklijke Philips Electronics, N.V. Automated annotation of clinical data
US20110166873A1 (en) * 2009-12-31 2011-07-07 Cerner Innovation, Inc. Patient-specific research consent manager
CA2728831A1 (en) * 2010-01-22 2011-07-22 Lifescan, Inc. Diabetes management unit, method, and system
WO2011100577A3 (en) * 2010-02-12 2011-12-29 Procure Treatment Centers, Inc. Robotic mobile anesthesia system
US8990135B2 (en) 2010-06-15 2015-03-24 The Regents Of The University Of Michigan Personalized health risk assessment for critical care
US8914319B2 (en) * 2010-06-15 2014-12-16 The Regents Of The University Of Michigan Personalized health risk assessment for critical care
US9138143B2 (en) 2010-08-17 2015-09-22 Fujitsu Limited Annotating medical data represented by characteristic functions
US8874607B2 (en) * 2010-08-17 2014-10-28 Fujitsu Limited Representing sensor data as binary decision diagrams
US20120046966A1 (en) * 2010-08-19 2012-02-23 International Business Machines Corporation Health Management Application Development and Deployment Framework
WO2014063118A1 (en) * 2012-10-19 2014-04-24 Apixio Inc. Systems and methods for medical information analysis with deidentification and reidentification
US9043901B2 (en) * 2010-09-01 2015-05-26 Apixio, Inc. Intent-based clustering of medical information
CN103098061B (en) * 2010-09-07 2018-04-13 皇家飞利浦电子股份有限公司 Clinical status timeline
US8666774B1 (en) 2010-11-19 2014-03-04 Hospitalists Now, Inc. System and method for gauging performance based on analysis of hospitalist and patient information
EP2656307B1 (en) * 2010-12-20 2017-07-05 Koninklijke Philips N.V. System and method for automatic generation of initial radiation treatment plans
US20120171650A1 (en) * 2010-12-29 2012-07-05 Warner Adrian F Methods and systems for developing medical waveforms and training methods
US20120173475A1 (en) * 2010-12-30 2012-07-05 Cerner Innovation, Inc. Health Information Transformation System
US9111018B2 (en) 2010-12-30 2015-08-18 Cerner Innovation, Inc Patient care cards
CN102178511A (en) * 2011-04-11 2011-09-14 Tcl集团股份有限公司 Disease prevention warning system and implementation method
US9286035B2 (en) 2011-06-30 2016-03-15 Infosys Limited Code remediation
US8517608B1 (en) 2011-08-03 2013-08-27 Ben A. Arnold System and method for calibration of CT scanners and display of images in density units without the use of water phantoms
US20130046153A1 (en) 2011-08-16 2013-02-21 Elwha LLC, a limited liability company of the State of Delaware Systematic distillation of status data relating to regimen compliance
US9311219B2 (en) * 2011-09-29 2016-04-12 Siemens Aktiengesellschaft Automatic trace retrieval using semantic bridge
US8856156B1 (en) 2011-10-07 2014-10-07 Cerner Innovation, Inc. Ontology mapper
US20130124217A1 (en) * 2011-11-11 2013-05-16 Debra Thesman Health plan rating system improvement program
WO2013088344A3 (en) * 2011-12-13 2013-08-15 Koninklijke Philips N.V. System and method for creating computer interpretable guidelines using a knowledge acquisition and management tool
KR101855179B1 (en) * 2011-12-21 2018-05-09 삼성전자 주식회사 Optimal diagnosis factor set determining apparatus and method for diagnosing a disease
US9477749B2 (en) 2012-03-02 2016-10-25 Clarabridge, Inc. Apparatus for identifying root cause using unstructured data
US20150058040A1 (en) * 2012-03-30 2015-02-26 Koninklijke Philips N.V. Method for synchronizing the state of a computer interpretable guideline engine with the state of patient care
US8930223B2 (en) * 2012-03-30 2015-01-06 International Business Machines Corporation Patient cohort matching
US9075796B2 (en) * 2012-05-24 2015-07-07 International Business Machines Corporation Text mining for large medical text datasets and corresponding medical text classification using informative feature selection
US20140025390A1 (en) * 2012-07-21 2014-01-23 Michael Y. Shen Apparatus and Method for Automated Outcome-Based Process and Reference Improvement in Healthcare
US20140058738A1 (en) * 2012-08-21 2014-02-27 International Business Machines Corporation Predictive analysis for a medical treatment pathway
US20140088989A1 (en) 2012-09-27 2014-03-27 Balaji Krishnapuram Rapid Learning Community for Predictive Models of Medical Knowledge
US20140089004A1 (en) * 2012-09-27 2014-03-27 University Of Utah Research Foundation Patient cohort laboratory result prediction
US20140095206A1 (en) * 2012-09-28 2014-04-03 Siemens Medical Solutions Usa, Inc. Adaptive medical documentation system
US20140149132A1 (en) * 2012-11-27 2014-05-29 Jan DeHaan Adaptive medical documentation and document management
US20140095204A1 (en) * 2012-09-28 2014-04-03 Siemens Medical Solutions Usa, Inc. Automated medical cohort determination
JP2014215935A (en) * 2013-04-30 2014-11-17 富士通株式会社 Information processing method, device, and program
US20140343955A1 (en) * 2013-05-16 2014-11-20 Verizon Patent And Licensing Inc. Method and apparatus for providing a predictive healthcare service
WO2014188476A1 (en) * 2013-05-20 2014-11-27 株式会社日立製作所 Healthcare information processing system
WO2014197669A1 (en) * 2013-06-05 2014-12-11 Nuance Communications, Inc. Methods and apparatus for providing guidance to medical professionals
WO2014201515A1 (en) * 2013-06-18 2014-12-24 Deakin University Medical data processing for risk prediction
US20150278459A1 (en) * 2013-06-28 2015-10-01 Hitachi, Ltd. Diagnostic process analysis system
EP3021739A4 (en) * 2013-07-18 2017-03-22 Parkland Center for Clinical Innovation Patient care surveillance system and method
US20150025908A1 (en) * 2013-07-19 2015-01-22 Hewlett-Packard Development Company, L.P. Clustering and analysis of electronic medical records
US20150039333A1 (en) * 2013-08-02 2015-02-05 Optum, Inc. Claim-centric grouper analysis
US20150081336A1 (en) * 2013-09-19 2015-03-19 Quintiles Transnational Corporation Electrical Computing Devices for Quantification of Differences in Medical Treatment Populations
US20150100344A1 (en) * 2013-10-08 2015-04-09 Chen Technology, Inc. Patient health information analysis system
WO2015055469A1 (en) * 2013-10-14 2015-04-23 Koninklijke Philips N.V. A unique methodology combining user roles and context aware algorithms for presenting clinical information, audio, video and communication controls to safely capture caregiver attention, reduce information overload, and optimize workflow and decision support
WO2015070867A1 (en) * 2013-11-12 2015-05-21 Ecbig (E-Commerce & Business Integration) Aps System and method of combining medicinal product information of medicaments
US20150149235A1 (en) * 2013-11-27 2015-05-28 General Electric Company Methods and systems to improve a quality of data employed by a healthcare analytics system
US9672256B2 (en) * 2014-02-04 2017-06-06 Microsoft Technology Licensing, Llc Creating data views
WO2015155588A3 (en) * 2014-04-08 2016-01-07 Pontificia Universidad Javeriana Method for prioritising electronic health records for retrospective studies
CN104063579B (en) * 2014-05-16 2017-08-15 上海亿保健康管理有限公司 Health-based dynamic prediction method and apparatus yuan for medical consumption data
CN104035980B (en) * 2014-05-26 2017-08-04 王和平 A searching method and system for structured information Medicine
CN104077495B (en) * 2014-07-17 2017-10-17 杜晓松 A wearable wireless body feature information collection and transmission module, the monitoring system
US20170249435A1 (en) * 2014-09-23 2017-08-31 Airstrip Ip Holdings, Llc Near-real-time transmission of serial patient data to third-party systems
US20170103182A1 (en) * 2015-01-25 2017-04-13 International Business Machines Corporation Modelling Disease Progression and Intervention Effects Using Non-Clinical Information Proxies for Clinical Information
US20160300015A1 (en) * 2015-04-08 2016-10-13 Oracle International Corporation Methods, systems, and computer readable media for integrating medical imaging data in a data warehouse
CN104881463B (en) * 2015-05-22 2018-01-16 清华大学深圳研究生院 Reference structured medical database records based on a search method and apparatus
CN106228020A (en) * 2016-07-29 2016-12-14 广州天健软件有限公司 Clinical data support system for respiratory diseases
CN106228023B (en) * 2016-08-01 2018-08-28 清华大学 Kinds of clinical pathway ontology and model-based mining theme
KR101869438B1 (en) * 2016-11-22 2018-06-20 네이버 주식회사 Method and system for predicting prognosis from diagnostic histories using deep learning

Citations (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946679A (en) * 1988-07-25 1990-08-07 Thys Jacobs Susan Method for the treatment of premenstrual syndrome
US5172418A (en) * 1989-08-10 1992-12-15 Fuji Photo Film Co., Ltd. Image processing apparatus using disease-based image processing conditions
US5619991A (en) * 1995-04-26 1997-04-15 Lucent Technologies Inc. Delivery of medical services using electronic data communications
US5657255A (en) * 1995-04-14 1997-08-12 Medical Science Systems, Inc. Hierarchical biological modelling system and method
US5664109A (en) * 1995-06-07 1997-09-02 E-Systems, Inc. Method for extracting pre-defined data items from medical service records generated by health care providers
US5724573A (en) * 1995-12-22 1998-03-03 International Business Machines Corporation Method and system for mining quantitative association rules in large relational tables
US5737539A (en) * 1994-10-28 1998-04-07 Advanced Health Med-E-Systems Corp. Prescription creation system
US5738102A (en) * 1994-03-31 1998-04-14 Lemelson; Jerome H. Patient monitoring system
US5811437A (en) * 1996-05-21 1998-09-22 Eli Lilly And Company Methods of increasing nitric oxide synthesis
US5845253A (en) * 1994-08-24 1998-12-01 Rensimer Enterprises, Ltd. System and method for recording patient-history data about on-going physician care procedures
US5903899A (en) * 1997-04-23 1999-05-11 Sun Microsystems, Inc. System and method for assisting exact Garbage collection by segregating the contents of a stack into sub stacks
US5908383A (en) * 1997-09-17 1999-06-01 Brynjestad; Ulf Knowledge-based expert interactive system for pain
US5924074A (en) * 1996-09-27 1999-07-13 Azron Incorporated Electronic medical records system
US5935060A (en) * 1996-07-12 1999-08-10 First Opinion Corporation Computerized medical diagnostic and treatment advice system including list based processing
US5939528A (en) * 1996-10-23 1999-08-17 Cornell Research Foundation, Inc. Crystalline FRAP complex
US5991731A (en) * 1997-03-03 1999-11-23 University Of Florida Method and system for interactive prescription and distribution of prescriptions in conducting clinical studies
US6039688A (en) * 1996-11-01 2000-03-21 Salus Media Inc. Therapeutic behavior modification program, compliance monitoring and feedback system
US6067466A (en) * 1998-11-18 2000-05-23 New England Medical Center Hospitals, Inc. Diagnostic tool using a predictive instrument
US6076088A (en) * 1996-02-09 2000-06-13 Paik; Woojin Information extraction system and method using concept relation concept (CRC) triples
US6081786A (en) * 1998-04-03 2000-06-27 Triangle Pharmaceuticals, Inc. Systems, methods and computer program products for guiding the selection of therapeutic treatment regimens
US6083693A (en) * 1996-06-14 2000-07-04 Curagen Corporation Identification and comparison of protein-protein interactions that occur in populations
US6108635A (en) * 1996-05-22 2000-08-22 Interleukin Genetics, Inc. Integrated disease information system
US6125194A (en) * 1996-02-06 2000-09-26 Caelum Research Corporation Method and system for re-screening nodules in radiological images using multi-resolution processing, neural network, and image processing
US6139494A (en) * 1997-10-15 2000-10-31 Health Informatics Tools Method and apparatus for an integrated clinical tele-informatics system
US6173280B1 (en) * 1998-04-24 2001-01-09 Hitachi America, Ltd. Method and apparatus for generating weighted association rules
US6196970B1 (en) * 1999-03-22 2001-03-06 Stephen J. Brown Research data collection and analysis
US6212526B1 (en) * 1997-12-02 2001-04-03 Microsoft Corporation Method for apparatus for efficient mining of classification models from databases
US6212519B1 (en) * 1998-06-30 2001-04-03 Simulconsult, Inc. Systems and methods for quantifying qualitative medical expressions
US6259890B1 (en) * 1997-03-27 2001-07-10 Educational Testing Service System and method for computer based test creation
US20010011243A1 (en) * 1999-06-02 2001-08-02 Ron Dembo Risk management system, distributed framework and method
US6272472B1 (en) * 1998-12-29 2001-08-07 Intel Corporation Dynamic linking of supplier web sites to reseller web sites
US20010023419A1 (en) * 1996-02-09 2001-09-20 Jerome Lapointe Method for selecting medical and biochemical diagnostic tests using neural network-related applications
US20010032195A1 (en) * 2000-03-30 2001-10-18 Graichen Catherine Mary System and method for identifying productivity improvements in a business organization
US20010041991A1 (en) * 2000-02-09 2001-11-15 Segal Elliot A. Method and system for managing patient medical records
US6322504B1 (en) * 2000-03-27 2001-11-27 R And T, Llc Computerized interactive method and system for determining a risk of developing a disease and the consequences of developing the disease
US20010051882A1 (en) * 1999-07-13 2001-12-13 Murphy Kevin M. Integrated care management system
US20020002474A1 (en) * 2000-01-28 2002-01-03 Michelson Leslie Dennis Systems and methods for selecting and recruiting investigators and subjects for clinical studies
US20020019746A1 (en) * 2000-03-16 2002-02-14 Rienhoff Hugh Y. Aggregating persons with a select profile for further medical characterization
US20020026332A1 (en) * 1999-12-06 2002-02-28 Snowden Guy B. System and method for automated creation of patient controlled records
US20020029155A1 (en) * 2000-08-04 2002-03-07 Frank Hetzel Registration and ordering system
US20020032581A1 (en) * 2000-07-17 2002-03-14 Reitberg Donald P. Single-patient drug trials used with accumulated database: risk of habituation
US20020077853A1 (en) * 2000-09-15 2002-06-20 Kevin Boru System for selecting clinical trials
US20020082480A1 (en) * 2000-08-29 2002-06-27 Riff Kenneth M. Medical device systems implemented network scheme for remote patient management
US20020099570A1 (en) * 2000-08-24 2002-07-25 Knight Stephen C. Recruiting a patient into a clinical trial
US20020107641A1 (en) * 1999-03-10 2002-08-08 Schaeffer Anthony J. Methods and kits for managing diagnosis and therapeutics of bacterial infections
US6468210B2 (en) * 2000-02-14 2002-10-22 First Opinion Corporation Automated diagnostic system and method including synergies
US6478737B2 (en) * 1999-06-03 2002-11-12 Cardiac Intelligence Corporation System and method for analyzing normalized patient voice feedback an automated collection and analysis patient care system
US6484144B2 (en) * 1999-03-23 2002-11-19 Dental Medicine International L.L.C. Method and system for healthcare treatment planning and assessment
US20020173990A1 (en) * 2001-05-15 2002-11-21 Dominic A. Marasco System and method for managing interactions between healthcare providers and pharma companies
US20020177759A1 (en) * 1996-12-30 2002-11-28 Ido Schoenberg Medical information text display system
US20030028401A1 (en) * 2001-07-17 2003-02-06 Leon Kaufman Customizable lung report generator
US6523019B1 (en) * 1999-09-21 2003-02-18 Choicemaker Technologies, Inc. Probabilistic record linkage model derived from training data
US6529876B1 (en) * 1999-03-26 2003-03-04 Stephen H. Dart Electronic template medical records coding system
US20030046114A1 (en) * 2001-08-28 2003-03-06 Davies Richard J. System, method, and apparatus for storing, retrieving, and integrating clinical, diagnostic, genomic, and therapeutic data
US6551266B1 (en) * 1998-12-29 2003-04-22 Occulogix Corporation Rheological treatment methods and related apheresis systems
US20030108938A1 (en) * 2001-11-06 2003-06-12 David Pickar Pharmacogenomics-based clinical trial design recommendation and management system and method
US6587829B1 (en) * 1997-07-31 2003-07-01 Schering Corporation Method and apparatus for improving patient compliance with prescriptions
US20030135391A1 (en) * 2001-10-31 2003-07-17 Edmundson Catherine M. Method and system for analyzing health information
US6611846B1 (en) * 1999-10-30 2003-08-26 Medtamic Holdings Method and system for medical patient data analysis
US6611825B1 (en) * 1999-06-09 2003-08-26 The Boeing Company Method and system for text mining using multidimensional subspaces
US6645959B1 (en) * 2000-01-26 2003-11-11 Warner-Lambert Company Method for treating postoperative ileus
US20040078216A1 (en) * 2002-02-01 2004-04-22 Gregory Toto Clinical trial process improvement method and system
US20040184644A1 (en) * 2002-10-31 2004-09-23 Cadvision Medical Technologies Ltd. Display for computer-aided evaluation of medical images and for establishing clinical recommendation therefrom
US6802810B2 (en) * 2001-09-21 2004-10-12 Active Health Management Care engine
US6804656B1 (en) * 1999-06-23 2004-10-12 Visicu, Inc. System and method for providing continuous, expert network critical care services from a remote location(s)
US20040243586A1 (en) * 2003-05-27 2004-12-02 Byers Frank Hugh Method and apparatus for obtaining and storing medical history records
US6839678B1 (en) * 1998-02-11 2005-01-04 Siemens Aktiengesellschaft Computerized system for conducting medical studies
US6903194B1 (en) * 1996-09-26 2005-06-07 Chungai Seiyaku Kabushiki Kaisha Antibody against human parathormone related peptides
US20050191716A1 (en) * 2000-01-11 2005-09-01 Zycare, Inc. Apparatus and methods for monitoring and modifying anticoagulation therapy of remotely located patients
US6941271B1 (en) * 2000-02-15 2005-09-06 James W. Soong Method for accessing component fields of a patient record by applying access rules determined by the patient
US6961687B1 (en) * 1999-08-03 2005-11-01 Lockheed Martin Corporation Internet based product data management (PDM) system
US7058658B2 (en) * 2000-03-28 2006-06-06 Dana-Farber Cancer Institute, Inc. Molecular database for antibody characterization
US20060136259A1 (en) * 2004-12-17 2006-06-22 General Electric Company Multi-dimensional analysis of medical data
US7130457B2 (en) * 2001-07-17 2006-10-31 Accuimage Diagnostics Corp. Systems and graphical user interface for analyzing body images
US7249006B2 (en) * 2000-03-23 2007-07-24 The Johns Hopkins University Method and system for bio-surveillance detection and alerting
US7307543B2 (en) * 1999-06-23 2007-12-11 Visicu, Inc. System and method for video observation of a patient in a health care location
US7353238B1 (en) * 1998-06-12 2008-04-01 Outcome Sciences, Inc. Apparatus and methods for determining and processing medical outcomes
US7630908B1 (en) * 2000-05-01 2009-12-08 John Amrien Wireless electronic prescription scanning and management system

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US567255A (en) * 1896-09-08 Michael p
ES2085285T3 (en) 1988-12-20 1996-06-01 Nippon Steel Corp Method and apparatus for managing the operation of a blast furnace.
US5508912A (en) * 1989-01-23 1996-04-16 Barry Schneiderman Clinical database of classified out-patients for tracking primary care outcome
WO1991017510A1 (en) 1990-05-01 1991-11-14 Healthchex, Inc. Health care services comparison processing
JP3006724B2 (en) * 1991-02-22 2000-02-07 ソニー株式会社 Mounting device
US5544044A (en) 1991-08-02 1996-08-06 United Healthcare Corporation Method for evaluation of health care quality
GB9117015D0 (en) * 1991-08-07 1991-09-18 Software Solutions Ltd Operation of computer systems
US5359509A (en) 1991-10-31 1994-10-25 United Healthcare Corporation Health care payment adjudication and review system
US5307262A (en) * 1992-01-29 1994-04-26 Applied Medical Data, Inc. Patient data quality review method and system
EP0596247A3 (en) 1992-11-02 1994-10-12 Motorola Inc A full-text index creation, search, retrieval and display method.
US5365425A (en) * 1993-04-22 1994-11-15 The United States Of America As Represented By The Secretary Of The Air Force Method and system for measuring management effectiveness
WO1995000914A1 (en) 1993-06-28 1995-01-05 Scott & White Memorial Hospital And Scott, Sherwood And Brindley Foundation Electronic medical record using text database
US5652842A (en) * 1994-03-01 1997-07-29 Healthshare Technology, Inc. Analysis and reporting of performance of service providers
US5669877A (en) 1994-03-07 1997-09-23 Sims Deltec, Inc. Systems and methods for automated testing of medical equipment
US5486999A (en) 1994-04-20 1996-01-23 Mebane; Andrew H. Apparatus and method for categorizing health care utilization
US5832447A (en) 1994-05-24 1998-11-03 Envoy Corporation Automated system and method for providing real-time verification of health insurance eligibility
US5557514A (en) * 1994-06-23 1996-09-17 Medicode, Inc. Method and system for generating statistically-based medical provider utilization profiles
US5706441A (en) * 1995-06-07 1998-01-06 Cigna Health Corporation Method and apparatus for objectively monitoring and assessing the performance of health-care providers
US5835897C1 (en) 1995-06-22 2002-02-19 Symmetry Health Data Systems Computer-implemented method for profiling medical claims
US5899998A (en) * 1995-08-31 1999-05-04 Medcard Systems, Inc. Method and system for maintaining and updating computerized medical records
US5924073A (en) * 1995-11-14 1999-07-13 Beacon Patient Physician Association, Llc System and method for assessing physician performance using robust multivariate techniques of statistical analysis
US6253186B1 (en) * 1996-08-14 2001-06-26 Blue Cross Blue Shield Of South Carolina Method and apparatus for detecting fraud
CA2216681A1 (en) 1996-09-30 1998-03-30 Dennis Langer Disease management method and system
US6212626B1 (en) * 1996-11-13 2001-04-03 Intel Corporation Computer processor having a checker
US6151581A (en) * 1996-12-17 2000-11-21 Pulsegroup Inc. System for and method of collecting and populating a database with physician/patient data for processing to improve practice quality and healthcare delivery
US6078894A (en) * 1997-03-28 2000-06-20 Clawson; Jeffrey J. Method and system for evaluating the performance of emergency medical dispatchers
US5937387A (en) * 1997-04-04 1999-08-10 Real Age, Inc. System and method for developing and selecting a customized wellness plan
US5903889A (en) 1997-06-09 1999-05-11 Telaric, Inc. System and method for translating, collecting and archiving patient records
US7018392B2 (en) * 1998-04-08 2006-03-28 Arthrocare Corporation Hemostatic system for body cavities
JP4183311B2 (en) 1997-12-22 2008-11-19 株式会社リコー Annotation of documents, annotation device and a recording medium
US6230142B1 (en) 1997-12-24 2001-05-08 Homeopt, Llc Health care data manipulation and analysis system
CN1155199C (en) 1998-02-23 2004-06-23 国际商业机器公司 Sequential chaining thermal target and continuous flow video browsing device in wanwei network browsing device
US6063693A (en) * 1998-03-23 2000-05-16 Telefonaktiebolaget Lm Ericsson Planar trenches
US20040067547A1 (en) 1998-03-31 2004-04-08 Stuart Harbron Rapid method for detecting micro-organisms and evaluating antimicrobial activity
DE19820276A1 (en) 1998-05-07 1999-11-18 Gerd Assmann Computation of global heart failure risk factors
US6338042B1 (en) * 1998-07-10 2002-01-08 Siemens Information And Communication Networks, Inc. Method and apparatus for integrating competency measures in compensation decisions
US6915254B1 (en) 1998-07-30 2005-07-05 A-Life Medical, Inc. Automatically assigning medical codes using natural language processing
US6266645B1 (en) 1998-09-01 2001-07-24 Imetrikus, Inc. Risk adjustment tools for analyzing patient electronic discharge records
US6341265B1 (en) 1998-12-03 2002-01-22 P5 E.Health Services, Inc. Provider claim editing and settlement system
US6381576B1 (en) * 1998-12-16 2002-04-30 Edward Howard Gilbert Method, apparatus, and data structure for capturing and representing diagnostic, treatment, costs, and outcomes information in a form suitable for effective analysis and health care guidance
WO2000042530A1 (en) * 1999-01-15 2000-07-20 Metaedge Corporation Method for visualizing information in a data warehousing environment
US6067486A (en) * 1999-02-01 2000-05-23 General Electric Company Method and system for planning repair of an aircraft engine
US6128620A (en) 1999-02-02 2000-10-03 Lemed Inc Medical database for litigation
US20040158193A1 (en) 1999-02-10 2004-08-12 Baxter International Inc. Medical apparatus using selective graphical interface
WO2000051054A1 (en) 1999-02-26 2000-08-31 Lipomed, Inc. Methods, systems, and computer program products for analyzing and presenting risk assessment results based on nmr lipoprotein analysis of blood
US6302844B1 (en) 1999-03-31 2001-10-16 Walker Digital, Llc Patient care delivery system
WO2000065522A3 (en) * 1999-04-28 2002-01-17 Univ State San Diego Electronic medical record registry including data replication
WO2000069331A1 (en) * 1999-05-17 2000-11-23 Pharmacon Global Enterprises, Llc Data processing system for patient outcome and risk benchmarking and healthcare data base management
US20020077756A1 (en) 1999-11-29 2002-06-20 Scott Arouh Neural-network-based identification, and application, of genomic information practically relevant to diverse biological and sociological problems, including drug dosage estimation
US20020038227A1 (en) * 2000-02-25 2002-03-28 Fey Christopher T. Method for centralized health data management
US6801816B2 (en) * 2000-02-28 2004-10-05 International Flavors & Fragrances Inc. Customer controlled manufacturing process and user interface
WO2001066007A1 (en) 2000-03-03 2001-09-13 Joerg Hohnloser Medical risk assessment system and method
US6988075B1 (en) * 2000-03-15 2006-01-17 Hacker L Leonard Patient-controlled medical information system and method
US7274810B2 (en) 2000-04-11 2007-09-25 Cornell Research Foundation, Inc. System and method for three-dimensional image rendering and analysis
JP2001297157A (en) 2000-04-12 2001-10-26 Terumo Corp Medical information communication equipment, control method therefor and storage medium
WO2001082135A1 (en) * 2000-04-21 2001-11-01 Science Applications International Corporation System and method of supply chain management
US7483838B1 (en) 2000-04-21 2009-01-27 James D. Marks System and method for recruitment of candidates for clinical trials while maintaining security
US20030036683A1 (en) * 2000-05-01 2003-02-20 Kehr Bruce A. Method, system and computer program product for internet-enabled, patient monitoring system
US20020010597A1 (en) 2000-05-19 2002-01-24 Mayer Gregg L. Systems and methods for electronic health management
US20030208382A1 (en) * 2001-07-05 2003-11-06 Westfall Mark D Electronic medical record system and method
US7698154B2 (en) 2000-07-20 2010-04-13 Marfly 1, LP Patient-controlled automated medical record, diagnosis, and treatment system and method
US6826536B1 (en) * 2000-07-22 2004-11-30 Bert Forman Health care billing monitor system for detecting health care provider fraud
US6915266B1 (en) * 2000-07-31 2005-07-05 Aysha Saeed Method and system for providing evaluation data from tracked, formatted administrative data of a service provider
WO2002019245A3 (en) * 2000-08-30 2003-10-30 Robert A Drazen Patient analysis and risk reduction system and associated methods
US6602136B1 (en) * 2000-10-11 2003-08-05 Igt Gaming device with a bonus scheme involving movement along paths with path change conditions
US20020123905A1 (en) * 2000-12-13 2002-09-05 Joane Goodroe Clinical operational and gainsharing information management system
US6938206B2 (en) 2001-01-19 2005-08-30 Transolutions, Inc. System and method for creating a clinical resume
US6551243B2 (en) * 2001-01-24 2003-04-22 Siemens Medical Solutions Health Services Corporation System and user interface for use in providing medical information and health care delivery support
US7346521B2 (en) * 2001-03-05 2008-03-18 Ims Health Incorporated System and methods for generating physician profiles concerning prescription therapy practices
US20020138492A1 (en) * 2001-03-07 2002-09-26 David Kil Data mining application with improved data mining algorithm selection
EP1246113A1 (en) 2001-03-09 2002-10-02 Pihl Limited Method & apparatus for delivering healthcare
US6879970B2 (en) * 2001-04-02 2005-04-12 Invivodata, Inc. Apparatus and method for prediction and management of subject compliance in clinical research
WO2002087431B1 (en) 2001-05-01 2003-01-03 Structural Bioinformatics Inc Diagnosing inapparent diseases from common clinical tests using bayesian analysis
US7444308B2 (en) * 2001-06-15 2008-10-28 Health Discovery Corporation Data mining platform for bioinformatics and other knowledge discovery
US20030050794A1 (en) 2001-09-07 2003-03-13 Marjorie Keck Hospital emergency department resource utilization and optimization system
JP4578742B2 (en) * 2001-09-27 2010-11-10 株式会社森精機製作所 Interference prevention device
JP2005509217A (en) * 2001-11-02 2005-04-07 シーメンス コーポレイト リサーチ インコーポレイテツド Mining of patient data, presentation, exploration and verification
US20040167804A1 (en) 2002-04-30 2004-08-26 Simpson Thomas L.C. Medical data communication notification and messaging system and method
US7698157B2 (en) 2002-06-12 2010-04-13 Anvita, Inc. System and method for multi-dimensional physician-specific data mining for pharmaceutical sales and marketing
US7725330B2 (en) 2002-12-03 2010-05-25 Siemens Medical Solutions Usa, Inc. Systems and methods for automated extraction and processing of billing information in patient records
US7523042B2 (en) 2003-01-17 2009-04-21 Providence Medical Group, A Division Of Providence Health System - Oregon Process and system for enhancing medical patient care
US20050256738A1 (en) 2004-05-11 2005-11-17 Petrimoulx Harold J Methods and systems for identifying health care professionals with a prescribed attribute
US20060020465A1 (en) 2004-07-26 2006-01-26 Cousineau Leo E Ontology based system for data capture and knowledge representation
US20060122864A1 (en) 2004-12-02 2006-06-08 Gottesman Janell M Patient management network
US20080275731A1 (en) 2005-05-18 2008-11-06 Rao R Bharat Patient data mining improvements
US8589185B2 (en) 2006-10-06 2013-11-19 Cerner Innovation, Inc. Acknowledgement of previous results for medication administration
US8560335B2 (en) 2006-10-06 2013-10-15 Cerner Innovation, Inc. Viewing clinical activity details within a selected time period
US8355924B2 (en) 2006-10-06 2013-01-15 Cerner Innovation, Inc. Patient activity coordinator
US8775208B2 (en) 2006-10-06 2014-07-08 Cerner Innovation, Inc. Patient outcomes in context of documentation
US20090171163A1 (en) 2007-12-31 2009-07-02 Mates John W Modular medical devices
US8754855B2 (en) 2008-06-27 2014-06-17 Microsoft Corporation Virtual touchpad
FR2944279B1 (en) 2009-04-09 2011-06-24 Rhodia Operations Method for producing a solution of diacid / diamine salts (s)

Patent Citations (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946679A (en) * 1988-07-25 1990-08-07 Thys Jacobs Susan Method for the treatment of premenstrual syndrome
US5172418A (en) * 1989-08-10 1992-12-15 Fuji Photo Film Co., Ltd. Image processing apparatus using disease-based image processing conditions
US6641532B2 (en) * 1993-12-29 2003-11-04 First Opinion Corporation Computerized medical diagnostic system utilizing list-based processing
US5738102A (en) * 1994-03-31 1998-04-14 Lemelson; Jerome H. Patient monitoring system
US5845253A (en) * 1994-08-24 1998-12-01 Rensimer Enterprises, Ltd. System and method for recording patient-history data about on-going physician care procedures
US5737539A (en) * 1994-10-28 1998-04-07 Advanced Health Med-E-Systems Corp. Prescription creation system
US5657255A (en) * 1995-04-14 1997-08-12 Medical Science Systems, Inc. Hierarchical biological modelling system and method
US5657255C1 (en) * 1995-04-14 2002-06-11 Interleukin Genetics Inc Hierarchic biological modelling system and method
US5619991A (en) * 1995-04-26 1997-04-15 Lucent Technologies Inc. Delivery of medical services using electronic data communications
US5664109A (en) * 1995-06-07 1997-09-02 E-Systems, Inc. Method for extracting pre-defined data items from medical service records generated by health care providers
US5724573A (en) * 1995-12-22 1998-03-03 International Business Machines Corporation Method and system for mining quantitative association rules in large relational tables
US6125194A (en) * 1996-02-06 2000-09-26 Caelum Research Corporation Method and system for re-screening nodules in radiological images using multi-resolution processing, neural network, and image processing
US6678669B2 (en) * 1996-02-09 2004-01-13 Adeza Biomedical Corporation Method for selecting medical and biochemical diagnostic tests using neural network-related applications
US20010023419A1 (en) * 1996-02-09 2001-09-20 Jerome Lapointe Method for selecting medical and biochemical diagnostic tests using neural network-related applications
US6076088A (en) * 1996-02-09 2000-06-13 Paik; Woojin Information extraction system and method using concept relation concept (CRC) triples
US5811437A (en) * 1996-05-21 1998-09-22 Eli Lilly And Company Methods of increasing nitric oxide synthesis
US6108635A (en) * 1996-05-22 2000-08-22 Interleukin Genetics, Inc. Integrated disease information system
US6083693A (en) * 1996-06-14 2000-07-04 Curagen Corporation Identification and comparison of protein-protein interactions that occur in populations
US5935060A (en) * 1996-07-12 1999-08-10 First Opinion Corporation Computerized medical diagnostic and treatment advice system including list based processing
US6903194B1 (en) * 1996-09-26 2005-06-07 Chungai Seiyaku Kabushiki Kaisha Antibody against human parathormone related peptides
US5924074A (en) * 1996-09-27 1999-07-13 Azron Incorporated Electronic medical records system
US5939528A (en) * 1996-10-23 1999-08-17 Cornell Research Foundation, Inc. Crystalline FRAP complex
US6039688A (en) * 1996-11-01 2000-03-21 Salus Media Inc. Therapeutic behavior modification program, compliance monitoring and feedback system
US20020177759A1 (en) * 1996-12-30 2002-11-28 Ido Schoenberg Medical information text display system
US5991731A (en) * 1997-03-03 1999-11-23 University Of Florida Method and system for interactive prescription and distribution of prescriptions in conducting clinical studies
US6259890B1 (en) * 1997-03-27 2001-07-10 Educational Testing Service System and method for computer based test creation
US5903899A (en) * 1997-04-23 1999-05-11 Sun Microsystems, Inc. System and method for assisting exact Garbage collection by segregating the contents of a stack into sub stacks
US6587829B1 (en) * 1997-07-31 2003-07-01 Schering Corporation Method and apparatus for improving patient compliance with prescriptions
US5908383A (en) * 1997-09-17 1999-06-01 Brynjestad; Ulf Knowledge-based expert interactive system for pain
US6139494A (en) * 1997-10-15 2000-10-31 Health Informatics Tools Method and apparatus for an integrated clinical tele-informatics system
US6212526B1 (en) * 1997-12-02 2001-04-03 Microsoft Corporation Method for apparatus for efficient mining of classification models from databases
US6839678B1 (en) * 1998-02-11 2005-01-04 Siemens Aktiengesellschaft Computerized system for conducting medical studies
US6081786A (en) * 1998-04-03 2000-06-27 Triangle Pharmaceuticals, Inc. Systems, methods and computer program products for guiding the selection of therapeutic treatment regimens
US6173280B1 (en) * 1998-04-24 2001-01-09 Hitachi America, Ltd. Method and apparatus for generating weighted association rules
US7353238B1 (en) * 1998-06-12 2008-04-01 Outcome Sciences, Inc. Apparatus and methods for determining and processing medical outcomes
US6754655B1 (en) * 1998-06-30 2004-06-22 Simulconsult, Inc. Systems and methods for diagnosing medical conditions
US6212519B1 (en) * 1998-06-30 2001-04-03 Simulconsult, Inc. Systems and methods for quantifying qualitative medical expressions
US6067466A (en) * 1998-11-18 2000-05-23 New England Medical Center Hospitals, Inc. Diagnostic tool using a predictive instrument
US6551266B1 (en) * 1998-12-29 2003-04-22 Occulogix Corporation Rheological treatment methods and related apheresis systems
US6272472B1 (en) * 1998-12-29 2001-08-07 Intel Corporation Dynamic linking of supplier web sites to reseller web sites
US20020107641A1 (en) * 1999-03-10 2002-08-08 Schaeffer Anthony J. Methods and kits for managing diagnosis and therapeutics of bacterial infections
US6196970B1 (en) * 1999-03-22 2001-03-06 Stephen J. Brown Research data collection and analysis
US6484144B2 (en) * 1999-03-23 2002-11-19 Dental Medicine International L.L.C. Method and system for healthcare treatment planning and assessment
US6529876B1 (en) * 1999-03-26 2003-03-04 Stephen H. Dart Electronic template medical records coding system
US20010011243A1 (en) * 1999-06-02 2001-08-02 Ron Dembo Risk management system, distributed framework and method
US6478737B2 (en) * 1999-06-03 2002-11-12 Cardiac Intelligence Corporation System and method for analyzing normalized patient voice feedback an automated collection and analysis patient care system
US6611825B1 (en) * 1999-06-09 2003-08-26 The Boeing Company Method and system for text mining using multidimensional subspaces
US7307543B2 (en) * 1999-06-23 2007-12-11 Visicu, Inc. System and method for video observation of a patient in a health care location
US6804656B1 (en) * 1999-06-23 2004-10-12 Visicu, Inc. System and method for providing continuous, expert network critical care services from a remote location(s)
US20010051882A1 (en) * 1999-07-13 2001-12-13 Murphy Kevin M. Integrated care management system
US6961687B1 (en) * 1999-08-03 2005-11-01 Lockheed Martin Corporation Internet based product data management (PDM) system
US6523019B1 (en) * 1999-09-21 2003-02-18 Choicemaker Technologies, Inc. Probabilistic record linkage model derived from training data
US6611846B1 (en) * 1999-10-30 2003-08-26 Medtamic Holdings Method and system for medical patient data analysis
US20020026332A1 (en) * 1999-12-06 2002-02-28 Snowden Guy B. System and method for automated creation of patient controlled records
US20050191716A1 (en) * 2000-01-11 2005-09-01 Zycare, Inc. Apparatus and methods for monitoring and modifying anticoagulation therapy of remotely located patients
US6645959B1 (en) * 2000-01-26 2003-11-11 Warner-Lambert Company Method for treating postoperative ileus
US20020002474A1 (en) * 2000-01-28 2002-01-03 Michelson Leslie Dennis Systems and methods for selecting and recruiting investigators and subjects for clinical studies
US20010041991A1 (en) * 2000-02-09 2001-11-15 Segal Elliot A. Method and system for managing patient medical records
US6468210B2 (en) * 2000-02-14 2002-10-22 First Opinion Corporation Automated diagnostic system and method including synergies
US6941271B1 (en) * 2000-02-15 2005-09-06 James W. Soong Method for accessing component fields of a patient record by applying access rules determined by the patient
US20020019746A1 (en) * 2000-03-16 2002-02-14 Rienhoff Hugh Y. Aggregating persons with a select profile for further medical characterization
US7249006B2 (en) * 2000-03-23 2007-07-24 The Johns Hopkins University Method and system for bio-surveillance detection and alerting
US6322504B1 (en) * 2000-03-27 2001-11-27 R And T, Llc Computerized interactive method and system for determining a risk of developing a disease and the consequences of developing the disease
US7058658B2 (en) * 2000-03-28 2006-06-06 Dana-Farber Cancer Institute, Inc. Molecular database for antibody characterization
US20010032195A1 (en) * 2000-03-30 2001-10-18 Graichen Catherine Mary System and method for identifying productivity improvements in a business organization
US7630908B1 (en) * 2000-05-01 2009-12-08 John Amrien Wireless electronic prescription scanning and management system
US20020032581A1 (en) * 2000-07-17 2002-03-14 Reitberg Donald P. Single-patient drug trials used with accumulated database: risk of habituation
US20020029155A1 (en) * 2000-08-04 2002-03-07 Frank Hetzel Registration and ordering system
US20020099570A1 (en) * 2000-08-24 2002-07-25 Knight Stephen C. Recruiting a patient into a clinical trial
US20020082480A1 (en) * 2000-08-29 2002-06-27 Riff Kenneth M. Medical device systems implemented network scheme for remote patient management
US20020077853A1 (en) * 2000-09-15 2002-06-20 Kevin Boru System for selecting clinical trials
US20020173990A1 (en) * 2001-05-15 2002-11-21 Dominic A. Marasco System and method for managing interactions between healthcare providers and pharma companies
US7130457B2 (en) * 2001-07-17 2006-10-31 Accuimage Diagnostics Corp. Systems and graphical user interface for analyzing body images
US20030028401A1 (en) * 2001-07-17 2003-02-06 Leon Kaufman Customizable lung report generator
US20030046114A1 (en) * 2001-08-28 2003-03-06 Davies Richard J. System, method, and apparatus for storing, retrieving, and integrating clinical, diagnostic, genomic, and therapeutic data
US6802810B2 (en) * 2001-09-21 2004-10-12 Active Health Management Care engine
US20030135391A1 (en) * 2001-10-31 2003-07-17 Edmundson Catherine M. Method and system for analyzing health information
US20030108938A1 (en) * 2001-11-06 2003-06-12 David Pickar Pharmacogenomics-based clinical trial design recommendation and management system and method
US20040078216A1 (en) * 2002-02-01 2004-04-22 Gregory Toto Clinical trial process improvement method and system
US20040184644A1 (en) * 2002-10-31 2004-09-23 Cadvision Medical Technologies Ltd. Display for computer-aided evaluation of medical images and for establishing clinical recommendation therefrom
US20040243586A1 (en) * 2003-05-27 2004-12-02 Byers Frank Hugh Method and apparatus for obtaining and storing medical history records
US20060136259A1 (en) * 2004-12-17 2006-06-22 General Electric Company Multi-dimensional analysis of medical data

Cited By (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7744540B2 (en) 2001-11-02 2010-06-29 Siemens Medical Solutions Usa, Inc. Patient data mining for cardiology screening
US20030120514A1 (en) * 2001-11-02 2003-06-26 Rao R. Bharat Patient data mining, presentation, exploration, and verification
US20030120133A1 (en) * 2001-11-02 2003-06-26 Rao R. Bharat Patient data mining for lung cancer screening
US20030120134A1 (en) * 2001-11-02 2003-06-26 Rao R. Bharat Patient data mining for cardiology screening
US20030125984A1 (en) * 2001-11-02 2003-07-03 Rao R. Bharat Patient data mining for automated compliance
US20030125985A1 (en) * 2001-11-02 2003-07-03 Rao R. Bharat Patient data mining for quality adherence
US20030125988A1 (en) * 2001-11-02 2003-07-03 Rao R. Bharat Patient data mining with population-based analysis
US20030126101A1 (en) * 2001-11-02 2003-07-03 Rao R. Bharat Patient data mining for diagnosis and projections of patient states
US7181375B2 (en) 2001-11-02 2007-02-20 Siemens Medical Solutions Usa, Inc. Patient data mining for diagnosis and projections of patient states
US8280750B2 (en) 2001-11-02 2012-10-02 Siemens Medical Solutions Usa, Inc. Patient data mining for cardiology screening
US20030120458A1 (en) * 2001-11-02 2003-06-26 Rao R. Bharat Patient data mining
US8949082B2 (en) 2001-11-02 2015-02-03 Siemens Medical Solutions Usa, Inc. Healthcare information technology system for predicting or preventing readmissions
US8214224B2 (en) 2001-11-02 2012-07-03 Siemens Medical Solutions Usa, Inc. Patient data mining for quality adherence
US7917377B2 (en) 2001-11-02 2011-03-29 Siemens Medical Solutions Usa, Inc. Patient data mining for automated compliance
US8214225B2 (en) 2001-11-02 2012-07-03 Siemens Medical Solutions Usa, Inc. Patient data mining, presentation, exploration, and verification
US8626533B2 (en) 2001-11-02 2014-01-07 Siemens Medical Soultions Usa, Inc. Patient data mining with population-based analysis
US8949079B2 (en) 2001-11-02 2015-02-03 Siemens Medical Solutions Usa, Inc. Patient data mining
US7711404B2 (en) 2001-11-02 2010-05-04 Siemens Medical Solutions Usa, Inc. Patient data mining for lung cancer screening
US20100222646A1 (en) * 2001-11-02 2010-09-02 Siemens Medical Solutions Usa, Inc. Patient Data Mining for Cardiology Screening
US8392152B2 (en) 2001-12-14 2013-03-05 Siemens Medical Solutions Usa, Inc. Early detection of disease outbreak using electronic patient data to reduce public health threat from bio-terrorism
US20090076851A1 (en) * 2001-12-14 2009-03-19 Siemens Medical Solutions Usa, Inc. Early detection of disease outbreak using electronic patient data to reduce public health threat from bio-terrorism
US8620677B2 (en) 2002-04-09 2013-12-31 Pcrs, Inc. Online, interactive evaluation of research performance
US8682693B2 (en) 2002-09-09 2014-03-25 Siemens Medical Solutions Usa, Inc. Patient data mining for lung cancer screening
US6826578B2 (en) * 2002-10-25 2004-11-30 Ge Medical Systems Information Technolgoies, Inc. Method, system, and computer product for collecting and distributing clinical data for data mining
US20040083217A1 (en) * 2002-10-25 2004-04-29 Cameron Brackett Method, system, and computer product for collecting and distributing clinical data for data mining
US7244230B2 (en) 2002-11-08 2007-07-17 Siemens Medical Solutions Usa, Inc. Computer aided diagnostic assistance for medical imaging
US20070106531A1 (en) * 2002-11-08 2007-05-10 Daniel Deakter Method and process that automatically finds patients for clinical drug or device trials
US20040093238A1 (en) * 2002-11-08 2004-05-13 Deakter Daniel R. System and process for matching patients with clinical medical trials
US20040147840A1 (en) * 2002-11-08 2004-07-29 Bhavani Duggirala Computer aided diagnostic assistance for medical imaging
US20040172293A1 (en) * 2003-01-21 2004-09-02 Paul Bruschi Method for identifying and communicating with potential clinical trial participants
US20070255584A1 (en) * 2003-09-08 2007-11-01 Pavlatos Christ J Patient Physician Connectivity System and Method
US20050086074A1 (en) * 2003-10-15 2005-04-21 Medical Web Technologies, Inc. Method and apparatus for sharing healthcare data
US7865373B2 (en) * 2003-10-15 2011-01-04 Medical Web Technologies, Inc. Method and apparatus for sharing healthcare data
WO2005081084A3 (en) * 2004-02-18 2005-12-01 Klaus Abraham-Fuchs Method for selecting a potential participant for a medical study on the basis of a selection criterion
WO2005081084A2 (en) * 2004-02-18 2005-09-01 Siemens Aktiengesellschaft Method for selecting a potential participant for a medical study on the basis of a selection criterion
US20050192836A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for delivering and gathering medical diagnostic data
US20050192843A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for validating patient and medical devices information
US20050192844A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for automatically collecting, formatting, and storing medical device data in a database
US20050192649A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for providing variable medical information
US20050192838A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for accessing and distributing medical information
US20050192842A1 (en) * 2004-02-27 2005-09-01 Cardiac Pacemakers, Inc. Systems and methods for authorizing and processing reimbursements for services provided in the collection of implantable medical device data
US20060184475A1 (en) * 2005-02-16 2006-08-17 Sriram Krishnan Missing data approaches in medical decision support systems
US7650321B2 (en) 2005-02-16 2010-01-19 Siemens Medical Solutions Usa, Inc. Two classifier based system for classifying anomalous medical patient records
US20060210133A1 (en) * 2005-03-03 2006-09-21 Sriram Krishnan Performance adjustments in medical decision support systems
WO2006096364A2 (en) 2005-03-03 2006-09-14 Siemens Medical Solutions Usa, Inc. Performance adjustments in medical decision support systems
US20060265253A1 (en) * 2005-05-18 2006-11-23 Rao R B Patient data mining improvements
US7630947B2 (en) 2005-08-25 2009-12-08 Siemens Medical Solutions Usa, Inc. Medical ontologies for computer assisted clinical decision support
US20070094188A1 (en) * 2005-08-25 2007-04-26 Pandya Abhinay M Medical ontologies for computer assisted clinical decision support
US20070067189A1 (en) * 2005-09-16 2007-03-22 Numoda Corporation Method and apparatus for screening, enrollment and management of patients in clinical trials
US8700649B2 (en) * 2005-12-06 2014-04-15 Optuminsight, Inc. Analyzing administrative healthcare claims data and other data sources
US20110231422A1 (en) * 2005-12-06 2011-09-22 Ingenix Inc. Analyzing administrative healthcare claims data and other data sources
US20070150372A1 (en) * 2005-12-19 2007-06-28 Roy Schoenberg Vendor and Consumer Matching
WO2007079442A1 (en) * 2006-01-03 2007-07-12 Invivodata, Inc. Apparatus and method for prediction and management of participant compliance in clinical research
US20070168345A1 (en) * 2006-01-17 2007-07-19 Andrew Gibbs System and method of identifying subject matter experts
US8670997B2 (en) 2006-02-09 2014-03-11 Siemens Medical Solutions Usa, Inc. Quality metric extraction and editing for medical data
US7844560B2 (en) 2006-04-17 2010-11-30 Siemens Medical Solutions Usa, Inc. Personalized prognosis modeling in medical treatment planning
US20070276777A1 (en) * 2006-04-17 2007-11-29 Siemens Medical Solutions Usa, Inc. Personalized Prognosis Modeling In Medical Treatment Planning
US20080033894A1 (en) * 2006-04-17 2008-02-07 Siemens Medical Solutions Usa, Inc. Prognosis Modeling From One or More Sources of Information
US7805385B2 (en) 2006-04-17 2010-09-28 Siemens Medical Solutions Usa, Inc. Prognosis modeling from literature and other sources
US20070250347A1 (en) * 2006-04-25 2007-10-25 Klaus Abraham-Fuchs Broker service and system architecture for health care data
US20080195600A1 (en) * 2006-05-25 2008-08-14 Deakter Daniel R Efficient method and process to search structured and unstructured patient data to match patients to clinical drug/device trials
US20100235378A1 (en) * 2006-08-22 2010-09-16 Lead Horse Technologies, Inc. Medical assessment support system and method
US7840511B2 (en) 2006-09-06 2010-11-23 Siemens Medical Solutions Usa, Inc. Learning or inferring medical concepts from medical transcripts using probabilistic models with words or phrases identification
US20080059391A1 (en) * 2006-09-06 2008-03-06 Siemens Medical Solutions Usa, Inc. Learning Or Inferring Medical Concepts From Medical Transcripts
US20080114616A1 (en) * 2006-11-10 2008-05-15 General Electric Company Method and system for clinical trial compliance
US8688475B2 (en) * 2006-11-10 2014-04-01 General Electric Company Method and system for clinical trial compliance
US20080201280A1 (en) * 2007-02-16 2008-08-21 Huber Martin Medical ontologies for machine learning and decision support
US7899764B2 (en) 2007-02-16 2011-03-01 Siemens Aktiengesellschaft Medical ontologies for machine learning and decision support
US20080228769A1 (en) * 2007-03-15 2008-09-18 Siemens Medical Solutions Usa, Inc. Medical Entity Extraction From Patient Data
US20090313045A1 (en) * 2008-06-11 2009-12-17 Boyce Mark D System and Method for Medical Research and Clinical Trial
US20100169115A1 (en) * 2008-12-31 2010-07-01 Tamis Robert H System for matching individuals with health care providers and methods thereof
US20120209628A1 (en) * 2008-12-31 2012-08-16 Tamis Robert H System for matching individuals with health care providers and methods thereof
US8751495B2 (en) 2009-09-29 2014-06-10 Siemens Medical Solutions Usa, Inc. Automated patient/document identification and categorization for medical data
US20110078145A1 (en) * 2009-09-29 2011-03-31 Siemens Medical Solutions Usa Inc. Automated Patient/Document Identification and Categorization For Medical Data
US20110184761A1 (en) * 2010-01-25 2011-07-28 Siemens Medical Solutions Usa, Inc. Method and Apparatus for Estimating Patient Populations
US20110238438A1 (en) * 2010-03-25 2011-09-29 Numoda Technologies, Inc. Automated method of graphically displaying predicted patient enrollment in a clinical trial study
US20120316898A1 (en) * 2011-06-08 2012-12-13 Levitt Tod S Scalable determination of probable patient eligibility for clinical trials and associated process for active solicitation of patients for clinical trials via their healthcare providers
US9298764B2 (en) * 2012-05-23 2016-03-29 Oracle International Corporation Partial source verification of EDC data
US20130318049A1 (en) * 2012-05-23 2013-11-28 Oracle International Corporation Partial source verification of edc data
US20140122113A1 (en) * 2012-06-06 2014-05-01 Cerner Innovation, Inc. Providing indications of clinical-trial criteria modifications
US9700292B2 (en) 2012-09-17 2017-07-11 DePuy Synthes Products, Inc. Systems and methods for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking
US9129054B2 (en) 2012-09-17 2015-09-08 DePuy Synthes Products, Inc. Systems and methods for surgical and interventional planning, support, post-operative follow-up, and, functional recovery tracking
WO2015139115A1 (en) * 2014-03-17 2015-09-24 Eqol Inc. System and method for managing illness outside of a hospital environment
US9747654B2 (en) 2014-12-09 2017-08-29 Cerner Innovation, Inc. Virtual home safety assessment framework
JP6262908B1 (en) * 2017-06-09 2018-01-17 リーズンホワイ株式会社 Medical system and medical program

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