New! View global litigation for patent families

US20030109925A1 - Accommodating intraocular lens - Google Patents

Accommodating intraocular lens Download PDF

Info

Publication number
US20030109925A1
US20030109925A1 US10329076 US32907602A US2003109925A1 US 20030109925 A1 US20030109925 A1 US 20030109925A1 US 10329076 US10329076 US 10329076 US 32907602 A US32907602 A US 32907602A US 2003109925 A1 US2003109925 A1 US 2003109925A1
Authority
US
Grant status
Application
Patent type
Prior art keywords
movement
optic
region
iol
lens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10329076
Inventor
Massoud Ghazizadeh
Joseph Weinschenk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADVANCED MEDICAL OTPICS Inc
Original Assignee
Allergan Sales Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1616Pseudo-accommodative, e.g. multifocal or enabling monovision
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1629Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1694Capsular bag spreaders therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE, IN GENERAL
    • B29DPRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00Producing optical elements, e.g. lenses or prisms
    • B29D11/02Artificial eyes from organic plastic material
    • B29D11/023Implants for natural eyes
    • B29D11/026Comprising more than one lens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1648Multipart lenses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2002/1681Intraocular lenses having supporting structure for lens, e.g. haptics

Abstract

An intraocular lens includes an optic for focusing light and a movement assembly coupled to the optic. The movement assembly is adapted to cooperate with the eye to effect accommodating movement of the optic. The movement assembly includes a plurality of movement members each with a proximal region coupled to the optic and an enlarged distal region. The enlarged distal region may be integral with the proximal region, or may be mechanically coupled thereto.

Description

    BACKGROUND OF THE INVENTION
  • [0001]
    The present invention relates to intraocular lenses (IOLs). More particularly, the present invention relates to IOLs which are adapted to provide accommodating movement in the eye.
  • [0002]
    The human visual system includes the eyes, the extraocular muscles which control eye position within the eye socket, the optic and other nerves that connect the eyes to the brain, and particular areas of the brain that are in neural communication with the eyes. The visual system is particularly well adapted for the rapid and precise extraction of spatial information from a field of view which is accomplished by analyzing the continuously changing patterns of radiant flux impinging upon the surfaces of the eyes.
  • [0003]
    Image formation is greatly complicated by the movement of the eyes within the head, as well as by the movement of both eyes and the head relative to the external sea of radiant energy. Visual input is ordinarily sampled by discrete momentary pauses of the eyes called fixations, interrupted by very rapid ballistic motions known as saccades which bring the eye from one fixation position to the next. Smooth movements of the eyes can occur when an object having a predictable motion is available to be followed.
  • [0004]
    Each eye forms an image upon a vast array of light sensitive photoreceptors of the retina. The cornea is the primary refracting surface which admits light through the anterior part of the outer surface of the eye. The iris contains muscles which alter the size of the entrance port of the eye, or pupil. The crystalline lens has a variable shape, under the indirect control of the ciliary muscle. Having a refractive index higher than the surrounding media, the crystalline lens gives the eye a variable focal length, allowing accommodation to objects at varying distances from the eye.
  • [0005]
    Much of the remainder of the eye is filled with fluids and materials under pressure which help the eye maintain its shape. For example, the aqueous humor fills the anterior chamber between the cornea and the iris, and the vitreous humor fills the majority of the volume of the eye in the vitreous chamber. The crystalline lens is contained within a third chamber of the eye, the posterior chamber, which is positioned between the anterior and vitreous chambers.
  • [0006]
    The human eye is susceptible to a score or more of disorders and diseases, a number of which attack the crystalline lens. For example, cataracts mar vision through cloudy or opaque discoloration of the lens of the eye. Cataracts often result in partial or complete blindness. If this is the case, the crystalline lens can be removed and replace with an intraocular lens, or IOL.
  • [0007]
    While restoring vision, conventional IOLs have limited ability for accommodation (i.e., the focusing on near objects). This condition is known as presbyopia. To overcome presbyopia of an IOL, a patient may be prescribed eyeglasses. Alternative attempts in the art to overcome presbyopia focus on providing IOLs with accommodation ability. Accommodation may be accomplished by either changing the shape of the IOL, e.g., to become more convex to focus on near objects, or by moving the IOL along its optical axis. For example, a number of these approaches bias an IOL to be located in the most posterior position of the posterior chamber of the eye under rest conditions. When near focus is required, the ciliary muscle contracts, and the IOL moves forwardly, which is known as positive accommodation. In the absence of ciliary muscle contraction, the IOL is biased rearwardly to the most posterior position. While these approaches may provide limited accommodation, the posterior bias and the configuration of the IOL prevent sufficient forward axial movement required for full-range accommodation.
  • [0008]
    In view of the foregoing, it would be beneficial in the art to provide IOLs adapted for sufficient accommodation to reduce significantly or to overcome the effects of presbyopia.
  • SUMMARY OF THE INVENTION
  • [0009]
    New intraocular lenses (IOLs) effective to provide accommodation have been discovered. The present IOLs provide effective accommodation using one or more optics. The IOLs of the invention also inhibit cell growth, particularly epithelial cell growth, onto the optics of the IOLs. The IOLs of the present invention are configured, and preferably promote cellular and fibrous growth to desired regions of the IOL, to increase the amount of force exerted by the eye against the IOLs to increase the amount of accommodation achieved. The present IOLs are relatively straightforward in design, can be produced using conventional IOL manufacturing procedures and can be inserted or implanted in eyes, e.g., human eyes, using surgical techniques which are the same as or analogous to such techniques used with conventional IOLs.
  • [0010]
    According to one aspect of the invention, an intraocular lens is provided which includes an optic for focusing light on a retina and a movement assembly coupled to the optic. The movement assembly is adapted to cooperate with the eye to effect accommodating movement of the optic. The movement assembly includes a movement member with a proximal region coupled to the optic. The movement member, and in particular the proximal region of the movement member, extends radially outwardly from the optic and includes an enlarged distal region with a contact surface adapted to be in contact with a peripheral region of a capsular bag of an eye.
  • [0011]
    One of the advantages of the present invention is that the IOL is held within, preferably attached to, the capsular bag. More specifically, the contact surface of the enlarged distal region may have an axial length of at least about 1 mm. Therefore, depending upon the radius of the IOL, the contact surface has a relatively large surface area with which to contact the capsular bag.
  • [0012]
    The contact of the IOL with the capsular bag is further enhanced by disposing the enlarged distal region in an angled manner relative to the proximal region of the member. Preferably, the contact surface is substantially parallel to the optical axis of the IOL. The relatively large contact surface is effective in maintaining the position of the IOL particularly directly following implantation and, on a long term basis, is effective in increasing the amount of accommodation provided by the IOL.
  • [0013]
    The relatively large surface area of the contact surface also promotes cellular and fibrous growth to or onto this region of the IOL, which further holds and retains the IOL within the capsular bag and increases the amount of force that may be exerted through the capsular bag onto the IOL to provide accommodation, as desired. Post-operative cellular and fibrous growth of the interior of the capsular bag to the enlarged distal region of the movement assembly may, and preferably does, enable the IOLs of the present invention to function substantially analogous to a natural crystalline lens.
  • [0014]
    To further facilitate this post-operative cellular growth, the enlarged distal region may include a plurality of depressions or through holes. Each of the through holes preferably provides increased growth of cells and fibrin onto the enlarged distal region or regions of the IOL. Accordingly, the IOL is very effectively attachable, preferably substantially permanently attachable, to the capsular bag. This attachment of the IOL to the capsular bag facilitates the axial movement of the IOL in direct response to changes in the capsular bag, therefore providing effective accommodation, analogous to a natural crystalline lens.
  • [0015]
    The IOLs of the present invention preferably inhibit unwanted posterior capsule opacification (PCO) of the optic. Thus, the distal region or regions of the movement assembly preferably is or are joined to the proximal region or regions so that one or more sharp edges, that is preferably edges which occur at discontinuities (rather than at smooth, continuous transitions) when viewed by the is naked human eye, are present between the joined proximal and distal regions. Such sharp edges have been found to advantageously inhibit PCO by inhibiting the growth of cells, for example, epithelial cells, from the capsular bag onto the optic of the present IOLs.
  • [0016]
    To further enhance the accommodating movement of the present IOLs in cooperation with the eye, the movement assembly preferably is positioned relative to the optic so that, with the IOL at rest, that is with no forces acting on the IOL to effect accommodation, the proximal region of the movement member is positioned at an angle other than 90° relative to the central optical axis of the optic. In a very useful embodiment, the optic, in the rest position as noted above, is anteriorly vaulted. Also, the movement member or members preferably include a hinge, or a plurality of hinges, located on the proximal region or regions of the movement members, more preferably closer to the optic than to the distal region or regions. Each of these features, either individually or any combination thereof, is effective to further facilitate the movement of the optic to provide the desired amount of accommodation.
  • [0017]
    According to another aspect of the invention, the movement assembly includes a plurality of movement members, preferably spaced apart, for example, radially or circumferentially spaced apart, from each other. Each movement member includes a proximal region coupled to the optic and an enlarged distal region, for example, as described elsewhere herein. The enlarged distal regions each have a contact surface adapted to be in contact with a peripheral region of a capsular bag of an eye. In addition, the enlarged distal regions may be configured such that the contact surfaces are substantially coaxial with the optical axis of the optic.
  • [0018]
    A plurality of spacer or cut-out regions preferably are located between radially or circumferentially adjacent movement members. Such cut-out regions are effective to prevent buckling of the IOL during accommodating movement in the eye. Such spacers or cut-out regions may be open. In one useful embodiment each of such regions is at least partially covered with or by a structural material having increased flexibility relative to the movement members. Thus, the IOL is prevented from buckling while, at the same time the structural material is effective to at least inhibit cell growth from the capsular bag onto the optic. This structural material may have the same chemical make-up as the proximal regions of the movement members and have a reduced thickness relative to the proximal regions to provide the increased flexibility.
  • [0019]
    Another advantage of the present IOLs is that a second optic may be provided. According to this multi-optic embodiment, the secondary optic may be coupled to the enlarged distal region or regions with one or more secondary movement members.
  • [0020]
    In one useful embodiment, the enlarged distal region or regions of the movement member or members are provided with a groove or grooves. The secondary movement member or members are adapted to fit into the groove or grooves, thereby holding the second optic in position in the eye. Alternately, the second optic and secondary movement members may be formed integrally with the optic/movement assembly combination.
  • [0021]
    In a further useful embodiment of present invention, the enlarged distal region or regions of the movement member or members are mechanically coupled to the perspective proximal regions. In one particular embodiment, an intraocular lens comprises a plurality of arcuate segments mechanically coupled (e.g., adhered) to an integrally formed optic and radially outward movement members. The arcuate segments may have one or more grooves for receiving one or more movement members, thus forming either a one-optic or a two-optic system.
  • [0022]
    The second optic preferably has an optical power, or even substantially no optical power. The combination of the optic and second optic together preferably provides the optical power required or desired by the patient in whose eye the IOL is to be implanted. For example, the second optic can have a plano or substantially plano optical power or a relatively highly negative optical power, for example, between about −30 diopters to about −10 diopters, as desired. The second optic preferably is located posterior of the optic. In one useful embodiment, the second optic, in the eye, is substantially maintained in contact with the inner posterior wall of the capsular bag. This feature inhibits or reduces the risk of cell growth or migration from the capsular bag into the second optic. The second optic in such a posterior position often has only a relatively restricted, if any, amount of axial movement. Such a posterior second optic preferably is posteriorly vaulted, with the IOL in the rest position as described elsewhere herein, to facilitate maintaining the posterior face of the second optic in contact with the inner posterior face of the capsular bag.
  • [0023]
    Any and all of the features described herein and combinations of such features are included within the scope of the present invention provided that the features of any such combination are not mutually inconsistent.
  • [0024]
    Additional aspects, features, and advantages of the present invention are set forth in the following description and claims, particularly when considered in conjunction with the accompanying drawings in which like parts bear like reference numbers.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0025]
    [0025]FIG. 1 is a perspective of an intraocular lens (IOL) according to an exemplary embodiment of the present invention, particularly illustrating an anterior side of the IOL.
  • [0026]
    [0026]FIG. 2 is a fragmentary cross-sectional view of an eye in which an IOL configured in accordance with the present invention has been implanted.
  • [0027]
    [0027]FIG. 3 is a plan view of an intraocular lens (IOL) of the invention, particularly illustrating a posterior side of the IOL.
  • [0028]
    [0028]FIG. 4 is a plan view of an alternate embodiment of an intraocular lens (IOL) of the invention, illustrating the use of flexible structural material between movement members.
  • [0029]
    [0029]FIG. 5 is an enlarged view of a two-lens system and a circumferential groove for receiving and retaining a posterior lens.
  • [0030]
    [0030]FIG. 6 is a plan view of and alternative embodiment of an intraocular lens (IOL) of the invention constructed of mechanically coupled lens and peripheral regions.
  • [0031]
    [0031]FIG. 7A is a plan view of one segment of a peripheral region of the IOL of FIG. 6.
  • [0032]
    [0032]FIG. 7B is an elevational view of the peripheral region segment of FIG. 7A.
  • [0033]
    [0033]FIG. 7C is an enlarged view of a portion of FIG. 7B.
  • [0034]
    [0034]FIG. 8 is a perspective view of a ring formed during the process of making the peripheral region of the IOL of FIG. 6.
  • DETAILED DESCRIPTION OF THE DRAWINGS
  • [0035]
    Referring to the drawings in more detail, an intraocular lens (IOL) 10 according to an exemplary embodiment of the present invention is illustrated in FIG. 1. Exemplary IOL 10 includes an optic 12 and a movement assembly 14 coupled to the optic 12. The optic 12, which has an optical axis O, is adapted to focus light on a retina of an eye. The movement assembly 14 of exemplary IOL 10 is adapted to cooperate with an eye to effect accommodating movement of the optic 12, which is discussed in detail below.
  • [0036]
    Exemplary movement assembly 14 includes a member 16 with a proximal region 18 and an enlarged distal region 20. The terms “proximal” and “distal” are used herein with respect to the distance from the optical axis O. The proximal region 18 is coupled to the optic 12 at a periphery 22 of the optic. The member 16 extends radially outwardly from the optic 12 and the proximal region 18 to the enlarged distal region 20. With additional reference to FIG. 2, the enlarged distal region 20 has a contact surface 24 which is adapted to be in contact with a peripheral region 26 of a capsular bag 28 of an eye 30.
  • [0037]
    Briefly describing the anatomy of the eye 30 with reference to FIG. 2, the capsular bag 28 is connected to a ciliary muscle 32 by suspensory ligaments or zonules 34. The ciliary muscle 32 is the prime mover in accommodation, i.e., in adjusting the eye 30 to focus on near objects. The zonules 34 retain the lens in position and are relaxed by the contraction of the ciliary muscle 32, thereby allowing a natural crystalline lens to become more convex.
  • [0038]
    Applying this anatomy to the present invention, exemplary IOL 10 is configured to facilitate movement of the optic 12 in response to the action of the ciliary muscle 32 and the zonules 34. When near vision is needed, the ciliary muscle 32 contracts, and the zonules 34 relax and reduce the equatorial diameter of the capsular bag 28, thereby moving the optic 12 anteriorly as indicated by arrow A in FIG. 2. This anterior movement of the optic 12 increases or amplifies the amount of positive (i.e., near) accommodation of the optic 12. Conversely, when the ciliary muscle 32 relaxes, the zonules 34 constrict and increase the equatorial diameter of the capsular bag 28, thus moving the optic posteriorly as indicated by arrow P.
  • [0039]
    For human implantation, exemplary IOL 10 may be configured such that the amount of positive or near accommodation is preferably at least about 1 diopter and may range up to 3.5 diopters or more. Further, exemplary IOL 10 may be configured to provide at least about 1.5 mm or 2 mm of axial movement anteriorly in the eye with about a reduction of about 1 mm in the equatorial diameter of the capsular bag 28 caused by the ciliary muscle 32 and the zonules 34.
  • [0040]
    As mentioned, the enlarged distal region 20 of the movement assembly 14 is adapted to be in contact with the peripheral region 26 of the capsular bag 28. In accordance with the invention, the contact surface 24 of the enlarged distal region 20 has a relatively large surface area. In other words, it is preferable to maximize the surface area of the contact surface 24 while maintaining the ability of the IOL 10 to be received within the capsular bag 28. By maximizing the surface area with which the IOL 10 contacts the capsular bag 28, the IOL 10 of the present invention effectively responds to changes in force exerted by the capsular bag 26 on the lens 10, thereby maximizing axial movement of the optic 12. In addition to the advantage of maximizing axial movement, the contact surface 24 of the enlarged distal region 20 also provides a large surface area to be subject to cellular and fibrous growth, which will be discussed in more detail below.
  • [0041]
    According to the exemplary embodiment of the invention shown in FIG. 1, the enlarged distal region 20 may be described as a plurality of peripheral arcuate bands with the contact surface 24 comprising the distal surface of each band. Each of the arcuate bands of the enlarged distal region 20 extends axially and has a length l, which will be discussed in more detail below. Each of the enlarged distal regions 20 may extend axially in a substantially parallel relationship with the optical axis O or, alternatively, may be arcuate in the axial direction such that the length l is an arc length λ (both symbols illustrated in FIG. 1 on one of the contact surfaces 24).
  • [0042]
    Regarding exemplary IOL 10 in more detail, the movement assembly 14 may include a plurality of cut-out regions 36 (e.g., four), thereby defining a corresponding plurality of spokes or haptic members 38. Each of the haptic members 38 includes a respective portion of the enlarged distal region 20 of the member 16 of the assembly 14. The cut-out regions 36 provide spatial relief when the ciliary muscle 32 contracts, thereby preventing buckling of the optic 12 during accommodation. To prevent posterior capsule opacification (PCO), each of the cut-out regions 36 may be filled with the same material from which the optic 12 is made.
  • [0043]
    Regarding the haptic members 38 in more detail, the haptic members 38 as shown in the exemplary embodiment of FIG. 1 may be substantially flat in configuration, flaring outwardly like pieces of a pie. The haptic members 38 desirably lie in planes angled with respect to the optical axis O to promote anterior movement, as further explained below. As mentioned, it is preferable to include four haptic members 38, such that each haptic member 38 may extend through nearly 90°, which extent is dependent upon the size of the cut-out regions 36.
  • [0044]
    To further enhance axial movement and accommodation, the haptic members 38 of exemplary movement assembly 14 may be angulated such that the optic 12 is positioned anterior to respective intersections 40 of the haptic members 38 and the enlarged distal regions 20, which is particularly shown in FIG. 2. For the purposes of this description, this angled configuration of the haptic members 38 is called “anterior angulation.” By angulating the haptic members 38 in this anterior manner, the movement assembly 14 is biased to move the optic 12 toward the anterior of the eye 30 when the ciliary muscle 32 contracts. Furthermore, the anterior angulation of the haptic members 38 ensures that the optic 12 moves in the anterior direction when the ciliary muscle 32 contracts.
  • [0045]
    With continued reference to FIGS. 1 and 2 and additional reference to FIG. 3, accommodation may be further enhanced by providing each of the haptic members 38 with a groove 41 formed in a posterior side thereof. The grooves 41 define an area of reduced thickness of each haptic member 38, thereby biasing the haptic members 38 to flex or pivot at the grooves 41. With such a construction, the grooves 41 accommodate flexing of the haptic members 38 in the anterior direction. As an alternative to the linear embodiment shown in FIG. 3, the grooves 41 may be arcuate and concentric with respective contact surfaces 24.
  • [0046]
    Axial movement may be further facilitated by providing a hinge 42 at the interior intersection 40 of each haptic member 38 with the respective portion of the enlarged distal region 20. The hinges 42 enhance the pivoting of the haptic members 38 relative to the enlarged distal region 20 when the ciliary muscle 32 contracts. In addition, each hinge 42 may be configured as a discontinuity, preferably a sharp edge, to retard or prevent cellular growth onto the haptic members 38 and the optic 12, thereby preventing PCO.
  • [0047]
    As mentioned above, the contact surface 24 of the enlarged distal region 20 has a large surface area, thereby providing a large surface area subject to cellular and fibrous growth. For example, each of the contact surfaces 24 of the enlarged distal region 20 may have an axial length l (or arcuate span λ) of at least about 1 mm and preferably on the order of about 2 mm. Therefore, depending upon the radius of the IOL 10, each of the contact surfaces 24 may have a surface area of the product of the axial length l and the arc length a.
  • [0048]
    Contact of the IOL 10 with the capsular bag 28 is further enhanced by disposing the enlarged distal region 20 in a perpendicular manner to the haptic members 38. Accordingly, the contact surface 24 is substantially parallel to the optical axis 10 of the IOL 10. The axial disposition of the enlarged contact surface 24 within the capsular bag 28 increases the retention of the IOL 10 therewithin, particularly immediately following implantation.
  • [0049]
    Post-operative cellular and fibrous growth of the interior of the capsular bag 28 to the enlarged distal region 20 of the movement assembly 14 enables the IOL 10 of the present invention to essentially fully function like a natural crystalline lens. The cellular and fibrous growth is facilitated by the close proximity of the contact surface 24 with the capsular bag 28.
  • [0050]
    To further facilitate this growth, the enlarged distal region 20 may include a plurality of depressions or holes 44. Each of the holes 44 provides a purchase on which cells and fibrin may grow. It is anticipated that this cellular and fibrous growth may take place within the first few weeks after the IOL 10 is implanted in an eye. Accordingly, the IOL 10 is permanently attachable to the capsular bag 28. This vigorous attachment of the IOL 10 to the capsular bag 28 ensures that the IOL 10 moves axially in direct response to changes in the capsular bag 28, therefore accommodating near vision, analogous to that of a natural crystalline lens.
  • [0051]
    With continued reference to FIGS. 2 and 3 and additional reference to FIG. 4, the IOL 10 of the present invention may be configured as a two-optic IOL. More specifically, exemplary IOL 10 may include a secondary optic 46 coupled to a secondary member 48. Analogous to member 16 described above, the secondary member 48 may include a proximal region coupled to the secondary optic 46 and a distal region, which distal region is either the enlarged distal region 20 described above, or a separate enlarged distal region, as indicated in the region 49. Further, the plurality of cut-out regions 36 may extend through the secondary member 48, thereby defining a plurality of secondary haptic members 50.
  • [0052]
    The secondary member 48 with secondary optic 46 may be integral with the enlarged distal region 20 or, alternatively, may be mechanically attached to the enlarged distal region 20 or member 16 to function as an auxiliary IOL. In one useful embodiment, the enlarged distal region 20 of the first movement member 10 is provided with a groove or channel (not shown). The secondary movement member 48 is adapted to fit into the groove, thereby holding the second optic 46 in position in the eye.
  • [0053]
    More specifically, the distal regions 49 of the secondary haptic members 50 may be adapted to attach to or be retained by the movement assembly 14 of the IOL 10. For example, a groove may be formed either on a posterior side of member 16 or, alternatively, on an interior side of the enlarged distal region 24. The latter type of groove is seen at 52 in FIG. 5. The groove 52 is sized so that ends of the distal regions 49 of the secondary haptic members 50 are receivable therein. The distal regions 49 may be permanently received within the groove 52 such as with adhesive or, alternatively, releasably received so that the secondary optic 46 may be replaced if needed or desired.
  • [0054]
    Analogous to the haptic members 38 described above, secondary haptic members 50 are angulated such that the secondary optic 46 is positioned posterior to respective intersections of the haptic members and the enlarged distal regions 20, which is particularly shown in FIG. 2. For the purposes of this description, this angled configuration of the secondary haptic members 50 will be called “posterior angulation.” By angulating the secondary haptic members 50 in this anterior manner, the movement assembly 14 is biased to move the secondary optic 46 toward the posterior of the eye 30 when the ciliary muscle 32 contracts.
  • [0055]
    In one useful embodiment each of the plurality of cut-out regions 36 in the secondary member 48 is at least partially filled with or covered by a structural material 51 having increased flexibility relative to the movement member. Thus, the second IOL is prevented from buckling while, at the same time the structural material 51 is effective to at least inhibit cell growth from the capsular bag onto the optic. This structural material 51 may have the same chemical make-up as the proximal regions of the movement members and have a reduced thickness relative to the proximal regions to provide the increased flexibility. In particular, the cut-out regions 36 may be filled with the same material from which the optic 46 is made.
  • [0056]
    [0056]FIG. 6 illustrates an alternative embodiment of the present invention in which an intraocular lens (IOL) 60 comprises an inner lens portion mechanically coupled to an outer peripheral region 62. In FIG. 6, the inner lens portion is shown in phantom and includes an optic 64 and a plurality of movement members 66 extending radially outwardly therefrom. As with the earlier embodiments, there are four such movement members 66 extending radially outward evenly about the optic 64, and each defining an included angle of nearly 90°.
  • [0057]
    As seen in FIGS. 6 and 7A-C, the outer peripheral region 62 comprises a plurality of individual arcuate segments 62 a-d disposed around the periphery of the IOL and each mechanically coupled to a movement member 66. In the illustrated embodiment, the movement member 66 are substantially pie-shaped and each of the arcuate segments 62 has a length that matches the outer circumferential arc of the respectively coupled movement member. Desirably, the included angle of each movement member 66 and coupled peripheral segment 62 is less than 90° so that cut-outs or spacer regions 68 are defined therebetween. In addition, the arc of the each segment 62 is desirably centered at the optical axis of the optic 64. As previously described, the spacer regions 68 each extend from the peripheral region 62 to the optic 64, and terminate at a radially inner curved end.
  • [0058]
    Various dimensions of each segment 62 are illustrated in the drawings and exemplary values provided herein. In a preferred embodiment, each of the arcuate segments 62 defines an included angle α of between 70-85°, and more particularly about 78°. Consequently, the angle β defined between the segments is between about 5-2020 , and more particularly about 12°. The exemplary embodiment has an outer radius ro of about 5.27 mm (0.2075 inches) and an inner radius ri of about 4.76 mm (0.187 inches).
  • [0059]
    With reference particularly to FIGS. 7B and 7C, each of the arcuate segments 62 includes a rounded outer surface 70 and a pair of grooves 72 a and 72 b defined on the inner surface. Each groove 72 is defined by a side wall 74, and a peripheral wall 76. The side walls 74 of the two grooves diverge but generally face each other, and the peripheral walls 76 are angled with respect one another and meet at an apex 78, desirably at the axial midplane of the segment 62.
  • [0060]
    Again, particular dimensions are shown in the drawings, with certain exemplary values provided herein. In particular, the axial thickness t of each arcuate segment 62 is about 1.02 mm (0.04 inches), while the outer peripheral radius rp is desirably about the same as the thickness t, namely about 1.02 mm (0.04 inches). The overall radial thickness A of each segment 62 is about 0.51 mm (0.02 inches), while the radial depth B of each of the grooves 72 is about 0.23 mm (0.009 inches). The axial width w of the two grooves 72 together is about 0.51 mm (0.02 inches), and the peripheral surface 76 of each groove defines an angle γ of about 10° at any one point with respect to a plane tangent to the entire arcuate segment 62 at that point. Finally, the included angle θ defined by the divergent side walls 74 of the two grooves 72 is about 20°.
  • [0061]
    Because there are two grooves 72 a,b, each arcuate segment 62 receives movement members 66 extending outward from two different optics 64. More particularly, FIG. 7C illustrates two movement members 66 a and 66 b disposed, respectively, within the grooves 72 a and 72 b and diverging at the included angle θ of the side walls 74. In other words, one of the optics is anteriorly vaulted and the other optic is posteriorly vaulted. The two movement members 66 a,b are desirably sized to precisely fit within grooves 72 a,b and contact at juxtaposed corners coincident with the apex 78. The resulting two-optic system can be customized to suit a wide variety of patient needs.
  • [0062]
    In a preferred manufacturing process, the segments 62 a-d are formed from a circular ring 80 as seen in FIG. 8. In particular, the ring 80 is molded using conventional means, and the segments 62 are then machined therefrom. Subsequently, the segments 62 are mechanically coupled to the respective movement members 66 using a suitable adhesive, or the like. Those of skill in the art will understand that there are various means other than adhesives for attaching movement members to peripheral structures. As a result, the IOL 60 has the benefit of an enlarged outer peripheral region 62 which helps distribute forces imparted by the ciliary muscles to the movement members 66, and thereafter to the optic 64. Such a force distribution system helps improve accommodation of the IOL 60.
  • [0063]
    The optics 12 and 46 may be constructed of rigid biocompatible materials such as polymethyl methacrylate (PMMA) or deformable materials such as silicone polymeric materials, acrylic polymeric materials, hydrogel polymeric materials, and the like. The deformable materials allow the IOL 10 to be rolled or folded for insertion through a small incision into the eye. Although the optic 12 as shown is a refractive lens body, the present IOLs may include a diffractive lens body, and such embodiment is included within the scope of the present invention.
  • [0064]
    The optic 12 may be either integral with or mechanically coupled to the member 16. The member 16 may be constructed of the same or different biocompatible materials as the optic 12, and is preferably made of polymeric materials such as polypropylene, silicone polymeric materials, acrylic polymeric materials, and the like. The movement assembly 14 is preferably deformable in much the same manner as the optic 12 to facilitate the passage of the IOL 10 through a small incision into the eye. The material or materials of construction from which the movement assembly 14 is made are chosen to provide the assembly with the desired mechanical properties, e.g., strength and deformability, to meet the needs of the particular application involved.
  • [0065]
    The IOL 10 may be inserted into the capsular bag 28 of a mammalian eye using conventional equipment and techniques, for example, after the natural crystalline lens is removed using a phaceomulsification technique. The IOL 10 is preferably rolled or folded prior to insertion into the eye so as to fit through a small incision, for example, on the order of about 3.2 mm. After insertion, the IOL 10 may be positioned in the eye as shown in FIG. 2.
  • [0066]
    If the IOL 10 is to be implanted in an adult human eye, the optic 12 preferably has a diameter in the range of about 3.5 mm to about 7 mm and, more preferably, in the range of about 5 mm to about 6 mm. Further, the IOL 10 may have an overall diameter, with the movement assembly 14 in an unstressed condition, of about 8 mm to about 11 mm or 12 mm. Additionally, the optic 12 preferably has a far-vision correction power for infinity in an accommodated state.
  • [0067]
    The present invention provides accommodating IOLs and methods for using such IOLs. The IOLs of the invention are configured to reduce the stretching of the capsular bag, to maintain the elasticity and/or integrity of the capsular bag, to enhance the effectiveness of the eye, particularly the function of the ciliary muscle and the zonules. The present IOLs promote the secure retention within the capsular bag by providing an enlarged contact surface to which cells and fibrin may grow. In addition, the present IOLs inhibit PCO. These benefits are obtained with IOLs which are streamlined in construction and relatively easy to manufacture and insert into the eye and which effectively provide accommodation for long-term use.
  • [0068]
    While the present invention has been described with respect to various specific examples and embodiments, it is to be understood that the invention is not limited thereto and that it can be variously practiced within the scope of the following claims.

Claims (34)

    What is claimed is:
  1. 1. An intraocular lens comprising:
    an optic adapted to focus light to a retina of an eye and having a central optical axis; and
    a movement assembly coupled to the optic and adapted to cooperate with the eye to effect accommodating movement of the optic;
    the movement assembly including a movement member having a proximal region coupled to the optic, the movement member extending radially outwardly from the optic and including an enlarged distal region having a contact surface adapted to be in contact with a peripheral region of a capsular bag of an eye.
  2. 2. The intraocular lens of claim 1 wherein the movement assembly is positioned relative to the optic so that, with the intraocular lens at rest, the proximal region of the movement member is positioned at an angle other than 90° relative to the central optical axis of the optic.
  3. 3. The intraocular lens of claim 1 wherein the movement assembly is adapted and configured to fit within the capsular bag of a human eye.
  4. 4. The intraocular lens of claim 1 wherein the enlarged distal region is configured so that the contact surface is angled with respect to the proximal region.
  5. 5. The intraocular lens of claim 1 wherein the enlarged distal region is configured so that the contact surface is substantially coaxial with the optical axis of the optic.
  6. 6. The intraocular lens of claim 5 wherein the contact surface has an axial length of at least about 1 mm.
  7. 7. The intraocular lens of claim 5 wherein the contact surface is rounded in a radial plane through the optical axis.
  8. 8. The intraocular lens of claim 1 wherein the enlarged distal region includes a plurality of through holes extending through the contact surface.
  9. 9. The intraocular lens of claim 1 wherein the movement assembly includes a plurality of the movement members circumferentially spaced apart.
  10. 10. The intraocular lens of claim 9 wherein, with the intraocular lens at rest, the proximal region of each of the plurality of movement members is positioned at an angle other than 90° relative to the central axis of the optic.
  11. 11. The intraocular lens of claim 9 wherein each of the plurality of movement members includes a hinge disposed proximally of the enlarged distal region.
  12. 12. The intraocular lens of claim 9 wherein the movement assembly includes a plurality of spacer regions located between circumferentially adjacent movement members, the spacer regions being open or at least partially covered with a structural material having increased flexibility relative to the movement members.
  13. 13. The intraocular lens of claim 1 further comprising a second optic coupled to the movement assembly.
  14. 14. The intraocular lens of claim 1 further comprising a second optic separate from the optic, and at least one haptic member coupled to the second optic and the distal region of the movement member.
  15. 15. The intraocular lens of claim 14 wherein, with the intraocular lens at rest, the optic is anteriorly vaulted and the secondary optic is posteriorly vaulted.
  16. 16. The intraocular lens of claim 1 wherein the proximal region is joined to the distal region so that one or more sharp edges are present between the proximal region and the distal region.
  17. 17. An intraocular lens comprising:
    an optic adapted to focus light to a retina of an eye and having a central optical axis; and
    a movement assembly coupled to the optic and adapted to cooperate with the eye to effect accommodating movement of the optic;
    the movement assembly including a plurality of movement members each having a proximal region coupled to the optic and an enlarged distal region; and
    each of the enlarged distal regions having a contact surface adapted to be in contact with a peripheral region of a capsular bag of an eye.
  18. 18. The intraocular lens of claim 17 wherein the movement assembly is positioned relative to the optic so that, with the intraocular lens at rest, the optic is anteriorly vaulted.
  19. 19. The intraocular lens of claim 17 wherein the movement assembly is adapted to fit within the capsular bag of a human eye.
  20. 20. The intraocular lens of claim 17 wherein each of the enlarged distal regions is configured such that the contact surface is angled with respect to the proximal region.
  21. 21. The intraocular lens of claim 17 wherein each of the enlarged distal regions is configured such that the contact surface thereof is substantially parallel with the optical axis of the optic.
  22. 22. The intraocular lens of claim 17 wherein each of the enlarged distal regions is configured such that the contact surface thereof is substantially rounded.
  23. 23. The intraocular lens of claim 17 wherein each of the enlarged distal regions includes a plurality of through holes extending through the contact surface.
  24. 24. The intraocular lens of claim 17 which is deformable to be passed through a small incision for insertion into an eye.
  25. 25. The intraocular lens of claim 17 wherein each of the plurality of movement members includes a hinge disposed proximally of the enlarged distal region.
  26. 26. The intraocular lens of claim 17 further comprising a second optic coupled to the movement assembly.
  27. 27. The intraocular lens of claim 26 wherein said movement assembly includes a plurality of haptic members, each haptic member being coupled to the second optic and to one of the enlarged distal regions.
  28. 28. The intraocular lens of claim 27, wherein the haptic members are positioned so that, with the intraocular lens at rest, the secondary optic is posteriorly vaulted.
  29. 29. The intraocular lens of claim 17, wherein each of the proximal regions is joined to one of the distal regions so that one or more sharp edges are present therebetween.
  30. 30. The intraocular lens of claim 17, and wherein the enlarged distal region of each movement member is formed separately from and mechanically coupled to the proximal region of that movement member.
  31. 31. The intraocular lens of claim 30, wherein the optic and the proximal region of each movement member are integrally formed, and wherein the movement assembly includes a plurality of the movement members circumferentially spaced apart.
  32. 32. The intraocular lens of claim 31, wherein each distal region comprises an arcuate segment having at least one groove for receiving and mechanically coupling to a proximal region of a movement member.
  33. 33. The intraocular lens of claim 32, wherein each arcuate segment includes a pair of grooves each for receiving and mechanically coupling to a proximal region of a movement member, the intraocular lens being a two-optic lens.
  34. 34. The intraocular lens of claim 30, wherein the enlarged distal region of each movement member is mechanically coupled to the proximal region of that movement member using adhesive.
US10329076 2000-03-09 2002-12-23 Accommodating intraocular lens Abandoned US20030109925A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US09522326 US6551354B1 (en) 2000-03-09 2000-03-09 Accommodating intraocular lens
US10329076 US20030109925A1 (en) 2000-03-09 2002-12-23 Accommodating intraocular lens

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10329076 US20030109925A1 (en) 2000-03-09 2002-12-23 Accommodating intraocular lens

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US09522326 Continuation US6551354B1 (en) 2000-03-09 2000-03-09 Accommodating intraocular lens

Publications (1)

Publication Number Publication Date
US20030109925A1 true true US20030109925A1 (en) 2003-06-12

Family

ID=24080414

Family Applications (2)

Application Number Title Priority Date Filing Date
US09522326 Active US6551354B1 (en) 2000-03-09 2000-03-09 Accommodating intraocular lens
US10329076 Abandoned US20030109925A1 (en) 2000-03-09 2002-12-23 Accommodating intraocular lens

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US09522326 Active US6551354B1 (en) 2000-03-09 2000-03-09 Accommodating intraocular lens

Country Status (6)

Country Link
US (2) US6551354B1 (en)
EP (1) EP1292247B1 (en)
JP (1) JP3958576B2 (en)
CA (1) CA2401972C (en)
DE (2) DE60126489T2 (en)
WO (1) WO2001066042A1 (en)

Cited By (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020116057A1 (en) * 2001-01-25 2002-08-22 Ting Albert C. Optic configuration for intraocular lens system
US20030078657A1 (en) * 2001-01-25 2003-04-24 Gholam-Reza Zadno-Azizi Materials for use in accommodating intraocular lens system
US20030109926A1 (en) * 2001-12-10 2003-06-12 Valdemar Portney Accommodating intraocular lens
US20040162612A1 (en) * 2003-02-13 2004-08-19 Valdemar Portney Accommodating intraocular lens system with enhanced range of motion
US20040190153A1 (en) * 2002-12-12 2004-09-30 Powervision Lens system and method for power adjustment using externally actuated micropumps
US20070010880A1 (en) * 2002-12-12 2007-01-11 Powervision, Inc. Methods of adjusting the power of an intraocular lens
US20070078515A1 (en) * 2005-09-30 2007-04-05 Brady Daniel G Deformable intraocular lenses and lens systems
US20070106377A1 (en) * 2002-12-12 2007-05-10 Powervision, Inc. Accommodating intraocular lens system having spherical aberration compensation and method
US20070191941A1 (en) * 2004-06-03 2007-08-16 Burkhard Dick Capsular equatorial ring
US20070213817A1 (en) * 2002-12-12 2007-09-13 Victor Esch Accommodating intraocular lens having peripherally actuated deflectable surface and method
US20070244560A1 (en) * 2006-04-12 2007-10-18 Alexei Ossipov Intraocular lens with distortion free valve
US20070260308A1 (en) * 2006-05-02 2007-11-08 Alcon, Inc. Accommodative intraocular lens system
US20080015689A1 (en) * 2002-12-12 2008-01-17 Victor Esch Accommodating Intraocular Lens System and Method
US20080046075A1 (en) * 2002-12-12 2008-02-21 Esch Victor C Accommodating Intraocular Lens System and Method
US20080125790A1 (en) * 2006-11-29 2008-05-29 George Tsai Apparatus and methods for compacting an intraocular lens
US20090018652A1 (en) * 2006-12-22 2009-01-15 Amo Groningen Bv Accommodating intraocular lenses and associated systems, frames, and methods
US7776088B2 (en) 2001-08-31 2010-08-17 Powervision, Inc. Intraocular lens system and method for power adjustment
US20110071628A1 (en) * 2009-09-24 2011-03-24 Rainbow Medical Ltd. Accommodative intraocular lens
US8048155B2 (en) 2002-02-02 2011-11-01 Powervision, Inc. Intraocular implant devices
US8158712B2 (en) 2007-02-21 2012-04-17 Powervision, Inc. Polymeric materials suitable for ophthalmic devices and methods of manufacture
US8303656B2 (en) 2003-03-06 2012-11-06 Powervision, Inc. Adaptive optic lens and method of making
US8314927B2 (en) 2007-07-23 2012-11-20 Powervision, Inc. Systems and methods for testing intraocular lenses
US20120310341A1 (en) * 2009-11-17 2012-12-06 Akkolens International B.V. Accommodative Intraocular Lens Driven by Ciliary Mass
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US8343216B2 (en) 2002-01-14 2013-01-01 Abbott Medical Optics Inc. Accommodating intraocular lens with outer support structure
US8361145B2 (en) 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
US8377123B2 (en) 2004-11-10 2013-02-19 Visiogen, Inc. Method of implanting an intraocular lens
US8425597B2 (en) 1999-04-30 2013-04-23 Abbott Medical Optics Inc. Accommodating intraocular lenses
US8447086B2 (en) 2009-08-31 2013-05-21 Powervision, Inc. Lens capsule size estimation
US8668734B2 (en) 2010-07-09 2014-03-11 Powervision, Inc. Intraocular lens delivery devices and methods of use
US8734512B2 (en) 2011-05-17 2014-05-27 James Stuart Cumming Biased accommodating intraocular lens
US8764823B2 (en) 2010-06-21 2014-07-01 James Stuart Cumming Semi-rigid framework for a plate haptic accommodating intraocular lens
US8900298B2 (en) 2010-02-23 2014-12-02 Powervision, Inc. Fluid for accommodating intraocular lenses
US8956408B2 (en) 2007-07-23 2015-02-17 Powervision, Inc. Lens delivery system
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
US9011532B2 (en) 2009-06-26 2015-04-21 Abbott Medical Optics Inc. Accommodating intraocular lenses
US9034036B2 (en) 2010-06-21 2015-05-19 James Stuart Cumming Seamless-vision, tilted intraocular lens
US9039760B2 (en) 2006-12-29 2015-05-26 Abbott Medical Optics Inc. Pre-stressed haptic for accommodating intraocular lens
US9198752B2 (en) 2003-12-15 2015-12-01 Abbott Medical Optics Inc. Intraocular lens implant having posterior bendable optic
US9271830B2 (en) 2002-12-05 2016-03-01 Abbott Medical Optics Inc. Accommodating intraocular lens and method of manufacture thereof
US9295545B2 (en) 2012-06-05 2016-03-29 James Stuart Cumming Intraocular lens
US9295546B2 (en) 2013-09-24 2016-03-29 James Stuart Cumming Anterior capsule deflector ridge
US9295544B2 (en) 2012-06-05 2016-03-29 James Stuart Cumming Intraocular lens
US9351825B2 (en) 2013-12-30 2016-05-31 James Stuart Cumming Semi-flexible posteriorly vaulted acrylic intraocular lens for the treatment of presbyopia
US9585745B2 (en) 2010-06-21 2017-03-07 James Stuart Cumming Foldable intraocular lens with rigid haptics
US9603703B2 (en) 2009-08-03 2017-03-28 Abbott Medical Optics Inc. Intraocular lens and methods for providing accommodative vision
US9610155B2 (en) 2008-07-23 2017-04-04 Powervision, Inc. Intraocular lens loading systems and methods of use
US9615916B2 (en) 2013-12-30 2017-04-11 James Stuart Cumming Intraocular lens
US9814570B2 (en) 1999-04-30 2017-11-14 Abbott Medical Optics Inc. Ophthalmic lens combinations
US9872763B2 (en) 2004-10-22 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
US9918830B2 (en) 2010-06-21 2018-03-20 James Stuart Cumming Foldable intraocular lens with rigid haptics
US9925039B2 (en) 2012-12-26 2018-03-27 Rainbow Medical Ltd. Accommodative intraocular lens

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040015236A1 (en) * 1991-11-18 2004-01-22 Sarfarazi Faezeh M. Sarfarazi elliptical accommodative intraocular lens for small incision surgery
EP1627613B8 (en) * 1995-02-15 2008-09-03 The Nice Trust, a Trust of the Isle of Man Accommodating intraocular lens having T-shaped haptics
US20060149369A1 (en) * 1997-05-20 2006-07-06 C&C Vision International Limited Accommodating arching lens
US8556967B2 (en) 1999-04-09 2013-10-15 Faezeh Mona Sarfarazi Interior bag for a capsular bag and injector
US7662179B2 (en) 1999-04-09 2010-02-16 Sarfarazi Faezeh M Haptics for accommodative intraocular lens system
US20040243232A1 (en) * 2002-09-13 2004-12-02 Eyeonics, Inc Lens for increased depth of focus
WO2002019949A3 (en) * 2000-09-07 2003-01-16 Allergan Sales Inc Intraocular lens with a posterior lens portion
US6884261B2 (en) * 2001-01-25 2005-04-26 Visiogen, Inc. Method of preparing an intraocular lens for implantation
US20030078658A1 (en) * 2001-01-25 2003-04-24 Gholam-Reza Zadno-Azizi Single-piece accomodating intraocular lens system
US7198640B2 (en) * 2001-01-25 2007-04-03 Visiogen, Inc. Accommodating intraocular lens system with separation member
US8062361B2 (en) * 2001-01-25 2011-11-22 Visiogen, Inc. Accommodating intraocular lens system with aberration-enhanced performance
US6818158B2 (en) * 2001-01-25 2004-11-16 Visiogen, Inc. Accommodating intraocular lens system and method of making same
US6524340B2 (en) 2001-05-23 2003-02-25 Henry M. Israel Accommodating intraocular lens assembly
DE10139027A1 (en) * 2001-08-15 2003-02-27 Humanoptics Ag The intraocular implant
WO2003059208A3 (en) * 2002-01-14 2004-05-13 Advanced Medical Optics Inc Accommodating intraocular lens with integral capsular bag ring
US20050021139A1 (en) * 2003-02-03 2005-01-27 Shadduck John H. Ophthalmic devices, methods of use and methods of fabrication
US6695881B2 (en) 2002-04-29 2004-02-24 Alcon, Inc. Accommodative intraocular lens
US20040034417A1 (en) * 2002-08-16 2004-02-19 Heyman Thomas M. Intraocular lens
US20040082993A1 (en) * 2002-10-25 2004-04-29 Randall Woods Capsular intraocular lens implant having a refractive liquid therein
US7125422B2 (en) * 2002-10-25 2006-10-24 Quest Vision Technology, Inc. Accommodating intraocular lens implant
US20040082995A1 (en) * 2002-10-25 2004-04-29 Randall Woods Telescopic intraocular lens implant for treating age-related macular degeneration
EP2671541A1 (en) * 2007-07-23 2013-12-11 PowerVision, Inc. Accommodating intraocular lenses and methods of use
US7615056B2 (en) 2003-02-14 2009-11-10 Visiogen, Inc. Method and device for compacting an intraocular lens
US20040249455A1 (en) * 2003-06-09 2004-12-09 Tran Son Trung Accommodative intraocular lens system
US20050125058A1 (en) * 2003-12-03 2005-06-09 Eyeonics, Inc. Accommodating hybrid intraocular lens
US7553327B2 (en) * 2003-12-04 2009-06-30 The Nice Trust, A Trust Of The Isle Of Man Accommodating 360 degree sharp edge optic plate haptic lens
US7645300B2 (en) * 2004-02-02 2010-01-12 Visiogen, Inc. Injector for intraocular lens system
US7780729B2 (en) 2004-04-16 2010-08-24 Visiogen, Inc. Intraocular lens
US7806929B2 (en) * 2004-08-27 2010-10-05 Brown David C Intracapsular pseudophakic device
US20060241752A1 (en) * 2005-04-20 2006-10-26 Israel Henry M Accommodating multiple lens assembly
US7771471B2 (en) 2005-05-13 2010-08-10 C & C Vision International Limited Floating optic accommodating intraocular lens
US7591849B2 (en) 2005-07-01 2009-09-22 Bausch & Lomb Incorpoted Multi-component accommodative intraocular lens with compressible haptic
US20070016293A1 (en) * 2005-07-18 2007-01-18 Alcon, Inc. Accommodative intraocular lens system
WO2007019389A1 (en) * 2005-08-05 2007-02-15 Visiogen, Inc. Accommodating diffractive intraocular lens
US20070032868A1 (en) * 2005-08-08 2007-02-08 Randall Woods Capsular shape-restoring device
US20070088433A1 (en) * 2005-10-17 2007-04-19 Powervision Accommodating intraocular lens system utilizing direct force transfer from zonules and method of use
US20070129803A1 (en) * 2005-12-06 2007-06-07 C&C Vision International Limited Accommodative Intraocular Lens
US20080294254A1 (en) * 2005-12-06 2008-11-27 Cumming J Stuart Intraocular lens
US20070129800A1 (en) * 2005-12-07 2007-06-07 C&C Vision International Limited Hydrolic accommodating intraocular lens
US7985253B2 (en) * 2005-12-07 2011-07-26 C&C Vision International Limited Hydrolic accommodating intraocular lens
US7981155B2 (en) * 2005-12-07 2011-07-19 C&C Vision International Limited Hydrolic accommodating intraocular lens
US20070168027A1 (en) * 2006-01-13 2007-07-19 Brady Daniel G Accommodating diffractive intraocular lens
US7837730B2 (en) * 2006-02-21 2010-11-23 C & C International Limited Floating optic accommodating intraocular lens
US20070260309A1 (en) * 2006-05-08 2007-11-08 Richardson Gary A Accommodating intraocular lens having a recessed anterior optic
EP2023857A2 (en) * 2006-05-08 2009-02-18 Bausch & Lomb Incorporated Accommodative intraocular lens having defined axial compression characteristics
US20080021549A1 (en) * 2006-07-21 2008-01-24 Eagan Barry T Accommodating intraocular lens having an active power source
US20080027539A1 (en) * 2006-07-25 2008-01-31 Cumming J Stuart "W" Accommodating Intraocular Lens
US7763070B2 (en) * 2006-07-25 2010-07-27 C&C Vision International Limited “W” accommodating intraocular lens
US8163015B2 (en) 2006-07-25 2012-04-24 C&C Vision International Limited “W” accommodating intraocular lens
US20080027538A1 (en) * 2006-07-27 2008-01-31 Cumming J Stuart Polyspheric Accommodating Intraocular Lens
US20080027540A1 (en) * 2006-07-31 2008-01-31 Cumming J Stuart Stabilized accommodating intraocular lens
US20080046077A1 (en) * 2006-08-15 2008-02-21 C&C Vision International Limited Multiocular Intraocular Lens Systems
WO2008079671A1 (en) * 2006-12-22 2008-07-03 Bausch & Lomb Incorporated Multi-element accommodative intraocular lens
CA2674018C (en) 2006-12-29 2015-05-26 Advanced Medical Optics, Inc. Multifocal accommodating intraocular lens
US7713299B2 (en) 2006-12-29 2010-05-11 Abbott Medical Optics Inc. Haptic for accommodating intraocular lens
US9398949B2 (en) * 2007-01-29 2016-07-26 Emmetropia, Inc. Intraocular lens system
US8066768B2 (en) * 2007-01-29 2011-11-29 Werblin Research & Development Corp. Intraocular lens system
US8066769B2 (en) * 2007-01-29 2011-11-29 Werblin Research & Development Corp. Intraocular lens system
US7811320B2 (en) * 2007-01-29 2010-10-12 Werblin Research & Development Corp. Intraocular lens system
US8034106B2 (en) * 2007-02-02 2011-10-11 Adoptics Ag Interfacial refraction accommodating lens (IRAL)
JP5108898B2 (en) * 2007-02-02 2012-12-26 Hoya株式会社 Interface refraction adjusting lens (IRAL)
US20080306587A1 (en) * 2007-02-21 2008-12-11 Jingjong Your Lens Material and Methods of Curing with UV Light
US20090005866A1 (en) * 2007-03-13 2009-01-01 C&C Vision International Limited First elastic hinge accommodating intraocular lens
US20080281415A1 (en) * 2007-03-13 2008-11-13 C&C Vision International Limited Second elastic hinge accommodating intraocular lens
US20080288066A1 (en) * 2007-05-16 2008-11-20 C&C Vision International Limited Toric sulcus lens
US8932351B2 (en) 2007-05-29 2015-01-13 Steven J. Dell Accommodative intraocular lens having a haptic plate
US20090228101A1 (en) * 2007-07-05 2009-09-10 Visiogen, Inc. Intraocular lens with post-implantation adjustment capabilities
US8414646B2 (en) * 2007-12-27 2013-04-09 Forsight Labs, Llc Intraocular, accommodating lens and methods of use
WO2009088448A3 (en) 2008-01-03 2010-04-15 Forsight Labs, Llc Intraocular, accomodating lens and methods of use
US8425595B2 (en) 2008-03-12 2013-04-23 Visiogen, Inc. Method for inserting an intraocular lens
US8034108B2 (en) * 2008-03-28 2011-10-11 Abbott Medical Optics Inc. Intraocular lens having a haptic that includes a cap
US20120232649A1 (en) 2008-11-20 2012-09-13 Insight Innovations, Llc Intraocular Lens Cell Migration Inhibition System
US9039762B2 (en) * 2010-03-23 2015-05-26 Novartis Ag Accommodating intraocular lens using trapezoidal phase shift
CA2861865A1 (en) 2012-01-24 2013-08-01 The Regents Of The University Of Colorado, A Body Corporate Modular intraocular lens designs and methods
US9364316B1 (en) 2012-01-24 2016-06-14 Clarvista Medical, Inc. Modular intraocular lens designs, tools and methods
WO2013158942A1 (en) * 2012-04-20 2013-10-24 Hanita Lenses R.C.A. Ltd. Intraocular assembly
JP5436618B2 (en) * 2012-06-05 2014-03-05 株式会社中京メディカル Intraocular lens
DE102012016893A1 (en) 2012-08-24 2014-05-15 Be Innovative Gmbh Intraocular lens, particularly Kapselsackintraokularlinse

Citations (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1483509A (en) * 1921-05-05 1924-02-12 Franklin Optical Company Process of making fused bifocal lenses
US2129305A (en) * 1936-08-21 1938-09-06 Feinbloom William Contact lens
US2274142A (en) * 1940-01-15 1942-02-24 Revalens Co Multifocal ophthalmic lens
US2405989A (en) * 1941-08-12 1946-08-20 Beach Lens Corp Lens
US2511517A (en) * 1947-01-31 1950-06-13 Bell & Howell Co Method of producing optical glass of varied refractive index
US3031927A (en) * 1958-03-03 1962-05-01 Plastic Contact Lens Company Bifocal corneal contact lens
US3034403A (en) * 1959-04-03 1962-05-15 Neefe Hamilton Res Company Contact lens of apparent variable light absorption
US3227507A (en) * 1961-08-16 1966-01-04 Feinbloom William Corneal contact lens having inner ellipsoidal surface
US3339997A (en) * 1962-07-30 1967-09-05 Plastic Contact Lens Company Bifocal ophthalmic lens having different color distance and near vision zones
US3420006A (en) * 1964-01-27 1969-01-07 Howard J Barnett Apparatus for grinding multifocal lens
US3431327A (en) * 1964-08-31 1969-03-04 George F Tsuetaki Method of making a bifocal contact lens with an embedded metal weight
US3693301A (en) * 1970-05-27 1972-09-26 Anvar Method for producing optical elements with aspherical surfaces
US3932148A (en) * 1975-01-21 1976-01-13 Criterion Manufacturing Company, Inc. Method and apparatus for making complex aspheric optical surfaces
US4162122A (en) * 1977-09-14 1979-07-24 Cohen Allen L Zonal bifocal contact lens
US4195919A (en) * 1977-10-31 1980-04-01 Shelton William A Contact lens with reduced spherical aberration for aphakic eyes
US4199231A (en) * 1978-08-21 1980-04-22 Evans Carl H Hydrogel contact lens
US4210391A (en) * 1977-09-14 1980-07-01 Cohen Allen L Multifocal zone plate
US4253199A (en) * 1978-09-25 1981-03-03 Surgical Design Corporation Surgical method and apparatus for implants for the eye
US4254509A (en) * 1979-04-09 1981-03-10 Tennant Jerald L Accommodating intraocular implant
US4274717A (en) * 1979-05-18 1981-06-23 Younger Manufacturing Company Ophthalmic progressive power lens and method of making same
US4315673A (en) * 1978-04-06 1982-02-16 Optische Werke G. Rodenstock Progressive power ophthalmic lens
US4316293A (en) * 1979-08-27 1982-02-23 Bayers Jon Herbert Flexible intraocular lens
US4338005A (en) * 1978-12-18 1982-07-06 Cohen Allen L Multifocal phase place
US4340283A (en) * 1978-12-18 1982-07-20 Cohen Allen L Phase shift multifocal zone plate
US4370760A (en) * 1981-03-25 1983-02-01 Kelman Charles D Anterior chamber intraocular lens
US4377329A (en) * 1980-02-26 1983-03-22 Stanley Poler Contact lens or the like
US4402579A (en) * 1981-07-29 1983-09-06 Lynell Medical Technology Inc. Contact-lens construction
US4404694A (en) * 1982-03-18 1983-09-20 Kelman Charles D Intraocular lens
US4504982A (en) * 1982-08-05 1985-03-19 Optical Radiation Corporation Aspheric intraocular lens
US4573775A (en) * 1982-08-19 1986-03-04 Vistakon, Inc. Bifocal contact lens
US4580882A (en) * 1983-04-21 1986-04-08 Benjamin Nuchman Continuously variable contact lens
US4596578A (en) * 1984-01-30 1986-06-24 Kelman Charles D Intraocular lens with miniature optic
US4636211A (en) * 1984-03-13 1987-01-13 Nielsen J Mchenry Bifocal intra-ocular lens
US4636049A (en) * 1983-09-20 1987-01-13 University Optical Products Co. Concentric bifocal contact lens
US4637697A (en) * 1982-10-27 1987-01-20 Pilkington P.E. Limited Multifocal contact lenses utilizing diffraction and refraction
US4641934A (en) * 1982-09-29 1987-02-10 Pilkington P.E. Limited Ophthalmic lens with diffractive power
US4676792A (en) * 1986-08-26 1987-06-30 Donald Praeger Method and artificial intraocular lens device for the phakic treatment of myopia
US4687484A (en) * 1983-12-12 1987-08-18 Kaplan Linda J Anterior chamber intraocular lens
US4693572A (en) * 1985-06-03 1987-09-15 Fused Kontacts Of Chicago, Inc. Monocentric bifocal corneal contact lens
US4720286A (en) * 1984-07-20 1988-01-19 Bailey Kelvin E Multifocus intraocular lens
US4752123A (en) * 1985-11-19 1988-06-21 University Optical Products Co. Concentric bifocal contact lens with two distance power regions
US4759762A (en) * 1985-03-08 1988-07-26 Grendahl Dennis T Accommodating lens
US4769033A (en) * 1987-07-02 1988-09-06 Nordan Lee T Intraocular multifocal lens
US4813955A (en) * 1983-09-07 1989-03-21 Manfred Achatz Multifocal, especially bifocal, intraocular, artificial ophthalmic lens
US4830481A (en) * 1988-08-12 1989-05-16 Minnesota Mining And Manufacturing Company Multifocal diffractive lens
US4842601A (en) * 1987-05-18 1989-06-27 Smith S Gregory Accommodating intraocular lens and method of implanting and using same
US4890913A (en) * 1982-10-13 1990-01-02 Carle John T De Zoned multi-focal contact lens
US4890912A (en) * 1986-01-24 1990-01-02 Rients Visser Trifocal eye-contact lens
US4892543A (en) * 1989-02-02 1990-01-09 Turley Dana F Intraocular lens providing accomodation
US4898461A (en) * 1987-06-01 1990-02-06 Valdemar Portney Multifocal ophthalmic lens
US4906246A (en) * 1987-08-24 1990-03-06 Grendahl Dennis T Cylindrically segmented zone of focus artificial hydrogel lens
US4917681A (en) * 1987-08-24 1990-04-17 Nordan Lee T Intraocular multifocal lens
US4919663A (en) * 1987-08-24 1990-04-24 Grendahl Dennis T Laminated zone of focus artificial hydrogel lens
US4921496A (en) * 1987-08-24 1990-05-01 Grendahl Dennis T Radially segemented zone of focus artificial hydrogel lens
US4923296A (en) * 1988-07-14 1990-05-08 Erickson Paul M Oriented simultaneous vision bifocal contact lenses or the like utilizing introaocular suppression of blur
US4932968A (en) * 1987-07-07 1990-06-12 Caldwell Delmar R Intraocular prostheses
US4932966A (en) * 1988-08-15 1990-06-12 Storz Instrument Company Accommodating intraocular lens
US4938583A (en) * 1986-06-02 1990-07-03 Miller Gregory N Contact lens and method of making same
US4955902A (en) * 1989-11-13 1990-09-11 Kelman Charles D Decentered intraocular lens
US4990159A (en) * 1988-12-02 1991-02-05 Kraff Manus C Intraocular lens apparatus with haptics of varying cross-sectional areas
US4994082A (en) * 1988-09-09 1991-02-19 Ophthalmic Ventures Limited Partnership Accommodating intraocular lens
US5000559A (en) * 1988-02-29 1991-03-19 Nikon Corporation Ophthalmic lenses having progressively variable refracting power
US5002382A (en) * 1989-12-07 1991-03-26 Leonard Seidner Multifocal corneal contact lenses
US5019099A (en) * 1987-07-02 1991-05-28 Nordan Lee T Intraocular multifocal lens method for correcting the aphakic eye
US5019098A (en) * 1989-05-19 1991-05-28 Essilor International Cie Generale D'optique Sight-correcting optical component such as an intra-ocular implant or contact lens
US5026396A (en) * 1990-05-07 1991-06-25 Darin John J Two-piece intraocular lens
US5047052A (en) * 1987-11-06 1991-09-10 Seymour Dubroff Anterior chamber intraocular lens with four point fixation
US5089024A (en) * 1988-04-19 1992-02-18 Storz Instrument Company Multi-focal intraocular lens
US5096285A (en) * 1990-05-14 1992-03-17 Iolab Corporation Multifocal multizone diffractive ophthalmic lenses
US5112351A (en) * 1990-10-12 1992-05-12 Ioptex Research Inc. Multifocal intraocular lenses
US5192318A (en) * 1986-06-05 1993-03-09 Schneider Richard T One-piece bifocal intraocular lens construction
US5192317A (en) * 1988-07-26 1993-03-09 Irvin Kalb Multi focal intra-ocular lens
US5201762A (en) * 1987-05-20 1993-04-13 Hauber Frederick A Intraocular archromatic lens
US5225858A (en) * 1987-06-01 1993-07-06 Valdemar Portney Multifocal ophthalmic lens
US5275623A (en) * 1991-11-18 1994-01-04 Faezeh Sarfarazi Elliptical accommodative intraocular lens for small incision surgery
US5443506A (en) * 1992-11-18 1995-08-22 Garabet; Antoine L. Lens with variable optical properties
US5480428A (en) * 1993-04-22 1996-01-02 Mezhotraslevoi Nauchno-Tekhnichesky Komplex "Mikrokhirurgia Glaza" Corrective intraocular lens
US5489302A (en) * 1994-05-24 1996-02-06 Skottun; Bernt C. Accommodating intraocular lens
US5496366A (en) * 1990-04-27 1996-03-05 Cumming; J. Stuart Accommodating intraocular lens
US5521656A (en) * 1987-06-01 1996-05-28 Portney; Valdemar Method of making an ophthalmic lens
US5549760A (en) * 1994-12-01 1996-08-27 White Consolidated Industries, Inc. Mounting device for dishwasher insulation
US5607472A (en) * 1995-05-09 1997-03-04 Emory University Intraocular lens for restoring accommodation and allows adjustment of optical power
US5609630A (en) * 1994-08-22 1997-03-11 Philippe Crozafon Intraocular implant
US5628796A (en) * 1994-07-04 1997-05-13 Suzuki; Taketoshi Intraocular lens
US5628795A (en) * 1995-03-15 1997-05-13 Langerman David W Spare parts for use in ophthalmic surgical procedures
US5652014A (en) * 1991-08-16 1997-07-29 Galin; Miles A. Medicament coated refractive anterior chamber ocular implant
US5652638A (en) * 1995-05-04 1997-07-29 Johnson & Johnson Vision Products, Inc. Concentric annular ring lens designs for astigmatism
US5766244A (en) * 1991-05-23 1998-06-16 Binder; Helmut Intraocular artificial lens and method for fabricating same
US5769890A (en) * 1997-01-16 1998-06-23 Henry H. McDonald Placement of second artificial lens in eye, to correct for optical defects of first artificial lens in eye
US5776191A (en) * 1982-02-05 1998-07-07 Staar Surgical Company Fixation system for intraocular lens structures
US5876442A (en) * 1998-01-15 1999-03-02 Visioncare Ltd. Intraocular lens implant with telescope support
US6013101A (en) * 1994-11-21 2000-01-11 Acuity (Israel) Limited Accommodating intraocular lens implant
US6096078A (en) * 1997-10-20 2000-08-01 Surgical Concepts, Inc. Accommodative lens implantation
US6176878B1 (en) * 1998-12-17 2001-01-23 Allergan Sales, Inc. Accommodating intraocular lens
US6186148B1 (en) * 1998-02-04 2001-02-13 Kiyoshi Okada Prevention of posterior capsular opacification
US6217612B1 (en) * 1999-09-10 2001-04-17 Randall Woods Intraocular lens implant having eye accommodating capabilities
US6224628B1 (en) * 1999-04-23 2001-05-01 Thinoptx, Inc. Haptics for an intraocular lens
US6387126B1 (en) * 1995-02-15 2002-05-14 J. Stuart Cumming Accommodating intraocular lens having T-shaped haptics

Family Cites Families (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25286E (en) 1962-11-13 Bifocal corneal contact lens
US3210894A (en) 1962-08-13 1965-10-12 Kollmorgen Corp Method of producing aspheric surfaces on mirrors or lenses
US3482906A (en) 1965-10-04 1969-12-09 David Volk Aspheric corneal contact lens series
US3542461A (en) 1967-11-20 1970-11-24 Du Pont Contact lens having an index of refraction approximating that of human tears
US4055378A (en) 1971-12-31 1977-10-25 Agfa-Gevaert Aktiengesellschaft Silicone contact lens with hydrophilic surface treatment
CA1012392A (en) 1973-08-16 1977-06-21 American Optical Corporation Progressive power ophthalmic lens
US3922728A (en) 1974-08-15 1975-12-02 Krasnov Mikhail M Artificial crystalline lens
DE2610203C3 (en) 1976-03-11 1988-07-28 Optische Werke G. Rodenstock, 8000 Muenchen, De
JPS5942286B2 (en) 1979-08-24 1984-10-13 Suwa Seikosha Kk
US4418991A (en) 1979-09-24 1983-12-06 Breger Joseph L Presbyopic contact lens
US4307945A (en) 1980-02-14 1981-12-29 Itek Corporation Progressively varying focal power opthalmic lens
USRE32525F1 (en) 1980-04-01 1989-05-09 Universal intraocular lens and a method of measuring an eye chamber size
US4409691A (en) 1981-11-02 1983-10-18 Levy Chauncey F Focussable intraocular lens
US4702244A (en) 1982-02-05 1987-10-27 Staar Surgical Company Surgical device for implantation of a deformable intraocular lens
DE3222099C2 (en) 1982-06-11 1984-06-20 Titmus Eurocon Kontaktlinsen Gmbh & Co Kg, 8750 Aschaffenburg, De
GB2124500B (en) 1982-07-22 1986-04-30 Mazzocco Thomas R Improved fixation system for intraocularers structures
US4888015A (en) 1982-08-20 1989-12-19 Domino Rudolph S Method of replacing an eye lens
US4476591A (en) 1982-10-07 1984-10-16 Arnott Eric J Lens implants for insertion in the human eye
DE3381691D1 (en) 1982-10-13 1990-08-02 Ng Trustees & Nominees Ltd Bifocal contact lenses.
DE3246306A1 (en) 1982-12-14 1984-06-14 Titmus Eurocon Kontaktlinsen Bifocal lens of bivisual type
US4725278A (en) * 1985-01-22 1988-02-16 Shearing Steven P Intraocular lens
US4618229A (en) 1983-07-22 1986-10-21 Bausch & Lomb Incorporated Bifocal contact lens
US4551864A (en) 1983-08-18 1985-11-12 Iolab Corporation Anterior chamber lens
GB2146791B (en) 1983-09-16 1987-01-28 Suwa Seikosha Kk Progressive multifocal ophthalmic lens
US4560383A (en) 1983-10-27 1985-12-24 Leiske Larry G Anterior chamber intraocular lens
US4629460A (en) * 1984-06-25 1986-12-16 Dyer Robert L Intraocular lens
US4976732A (en) 1984-09-12 1990-12-11 International Financial Associates Holdings, Inc. Optical lens for the human eye
GB2192291B (en) 1986-03-04 1990-08-22 Gupta Anil K Progressive power contact lens.
US4725277A (en) 1986-05-14 1988-02-16 Precision-Cosmet Co., Inc. Intraocular lens with tapered haptics
US4790847A (en) 1987-05-26 1988-12-13 Woods Randall L Intraocular lens implant having eye focusing capabilities
US5166711A (en) 1987-06-01 1992-11-24 Valdemar Portney Multifocal ophthalmic lens
US5166712A (en) 1987-06-01 1992-11-24 Valdemar Portney Multifocal ophthalmic lens
US5158572A (en) 1987-09-10 1992-10-27 Nielsen James Mchenry Multifocal intraocular lens
US4881804A (en) 1987-11-12 1989-11-21 Cohen Allen L Multifocal phase plate with a pure refractive portion
US4888012A (en) 1988-01-14 1989-12-19 Gerald Horn Intraocular lens assemblies
GB8802220D0 (en) 1988-02-02 1988-03-02 Grendahl D T Intraocular lens
EP0329981A1 (en) 1988-02-11 1989-08-30 ADVANCE MEDICAL S.r.l. Intraocular lens with chromatic and absorption-diagram correction
FR2631228B1 (en) 1988-05-11 1990-08-10 Domilens Laboratoires Intraocular implant anterior chamber
US4932970A (en) 1988-05-17 1990-06-12 Allergan, Inc. Ophthalmic lens
EP0681198A1 (en) 1988-07-20 1995-11-08 Allen L. Dr. Cohen Multifocal ophthalmic lens
FR2642854B1 (en) 1989-02-03 1991-05-03 Essilor Int optical lens simultaneous vision for the correction of presbyopia
US6197059B1 (en) * 1990-04-27 2001-03-06 Medevec Licensing, B.V. Accomodating intraocular lens
US5147397A (en) 1990-07-03 1992-09-15 Allergan, Inc. Intraocular lens and method for making same
US5171266A (en) 1990-09-04 1992-12-15 Wiley Robert G Variable power intraocular lens with astigmatism correction
US5173723A (en) 1990-10-02 1992-12-22 Volk Donald A Aspheric ophthalmic accommodating lens design for intraocular lens and contact lens
US5260727A (en) 1990-10-22 1993-11-09 Oksman Henry C Wide depth of focus intraocular and contact lenses
US5258025A (en) 1990-11-21 1993-11-02 Fedorov Svjatoslav N Corrective intraocular lens
US5326347A (en) 1991-08-12 1994-07-05 Cumming J Stuart Intraocular implants
US5578081A (en) 1991-11-12 1996-11-26 Henry H. McDonald Eye muscle responsive artificial lens unit
NL9200400A (en) 1992-03-04 1993-10-01 Jose Jorge Pavlotzky Handelend Bifocal contact lens, as well as method for manufacturing of such a contact lens.
US5354335A (en) 1993-02-04 1994-10-11 Isaac Lipshitz Intraocular insert for implantation in the human eye
US5682223A (en) 1995-05-04 1997-10-28 Johnson & Johnson Vision Products, Inc. Multifocal lens designs with intermediate optical powers
US5684560A (en) 1995-05-04 1997-11-04 Johnson & Johnson Vision Products, Inc. Concentric ring single vision lens designs
US6322589B1 (en) * 1995-10-06 2001-11-27 J. Stuart Cumming Intraocular lenses with fixated haptics
WO1997043984A1 (en) * 1996-05-17 1997-11-27 Helmut Payer An ocular implant
US5928283A (en) 1997-06-26 1999-07-27 Visioncare Ltd Telescopic device for an intraocular lens
US5814103A (en) 1998-01-15 1998-09-29 Visioncare Ltd. Intraocular lens and telescope with mating fasteners
DE60029102D1 (en) * 1999-04-30 2006-08-10 Advanced Medical Optics Inc movable intraocular lens
DE50013494D1 (en) * 1999-12-14 2006-11-02 Boehm Hans Georg Fokussierfähige intraocular lens
FR2804860B1 (en) * 2000-02-16 2002-04-12 Humanoptics Ag Implant cristallinien accomodatif
US6797004B1 (en) * 2000-03-02 2004-09-28 Advanced Medical Optics, Inc. Holders for intraocular lenses

Patent Citations (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1483509A (en) * 1921-05-05 1924-02-12 Franklin Optical Company Process of making fused bifocal lenses
US2129305A (en) * 1936-08-21 1938-09-06 Feinbloom William Contact lens
US2274142A (en) * 1940-01-15 1942-02-24 Revalens Co Multifocal ophthalmic lens
US2405989A (en) * 1941-08-12 1946-08-20 Beach Lens Corp Lens
US2511517A (en) * 1947-01-31 1950-06-13 Bell & Howell Co Method of producing optical glass of varied refractive index
US3031927A (en) * 1958-03-03 1962-05-01 Plastic Contact Lens Company Bifocal corneal contact lens
US3034403A (en) * 1959-04-03 1962-05-15 Neefe Hamilton Res Company Contact lens of apparent variable light absorption
US3227507A (en) * 1961-08-16 1966-01-04 Feinbloom William Corneal contact lens having inner ellipsoidal surface
US3339997A (en) * 1962-07-30 1967-09-05 Plastic Contact Lens Company Bifocal ophthalmic lens having different color distance and near vision zones
US3420006A (en) * 1964-01-27 1969-01-07 Howard J Barnett Apparatus for grinding multifocal lens
US3431327A (en) * 1964-08-31 1969-03-04 George F Tsuetaki Method of making a bifocal contact lens with an embedded metal weight
US3693301A (en) * 1970-05-27 1972-09-26 Anvar Method for producing optical elements with aspherical surfaces
US3932148A (en) * 1975-01-21 1976-01-13 Criterion Manufacturing Company, Inc. Method and apparatus for making complex aspheric optical surfaces
US4210391A (en) * 1977-09-14 1980-07-01 Cohen Allen L Multifocal zone plate
US4162122A (en) * 1977-09-14 1979-07-24 Cohen Allen L Zonal bifocal contact lens
US4195919A (en) * 1977-10-31 1980-04-01 Shelton William A Contact lens with reduced spherical aberration for aphakic eyes
US4315673A (en) * 1978-04-06 1982-02-16 Optische Werke G. Rodenstock Progressive power ophthalmic lens
US4199231A (en) * 1978-08-21 1980-04-22 Evans Carl H Hydrogel contact lens
US4253199A (en) * 1978-09-25 1981-03-03 Surgical Design Corporation Surgical method and apparatus for implants for the eye
US4338005A (en) * 1978-12-18 1982-07-06 Cohen Allen L Multifocal phase place
US4340283A (en) * 1978-12-18 1982-07-20 Cohen Allen L Phase shift multifocal zone plate
US4254509A (en) * 1979-04-09 1981-03-10 Tennant Jerald L Accommodating intraocular implant
US4274717A (en) * 1979-05-18 1981-06-23 Younger Manufacturing Company Ophthalmic progressive power lens and method of making same
US4316293A (en) * 1979-08-27 1982-02-23 Bayers Jon Herbert Flexible intraocular lens
US4377329A (en) * 1980-02-26 1983-03-22 Stanley Poler Contact lens or the like
US4370760A (en) * 1981-03-25 1983-02-01 Kelman Charles D Anterior chamber intraocular lens
US4402579A (en) * 1981-07-29 1983-09-06 Lynell Medical Technology Inc. Contact-lens construction
US5776191A (en) * 1982-02-05 1998-07-07 Staar Surgical Company Fixation system for intraocular lens structures
US4404694A (en) * 1982-03-18 1983-09-20 Kelman Charles D Intraocular lens
US4504982A (en) * 1982-08-05 1985-03-19 Optical Radiation Corporation Aspheric intraocular lens
US4573775A (en) * 1982-08-19 1986-03-04 Vistakon, Inc. Bifocal contact lens
US4641934A (en) * 1982-09-29 1987-02-10 Pilkington P.E. Limited Ophthalmic lens with diffractive power
US4890913A (en) * 1982-10-13 1990-01-02 Carle John T De Zoned multi-focal contact lens
US4637697A (en) * 1982-10-27 1987-01-20 Pilkington P.E. Limited Multifocal contact lenses utilizing diffraction and refraction
US4580882A (en) * 1983-04-21 1986-04-08 Benjamin Nuchman Continuously variable contact lens
US4813955A (en) * 1983-09-07 1989-03-21 Manfred Achatz Multifocal, especially bifocal, intraocular, artificial ophthalmic lens
US4636049A (en) * 1983-09-20 1987-01-13 University Optical Products Co. Concentric bifocal contact lens
US4687484A (en) * 1983-12-12 1987-08-18 Kaplan Linda J Anterior chamber intraocular lens
US4596578A (en) * 1984-01-30 1986-06-24 Kelman Charles D Intraocular lens with miniature optic
US4636211A (en) * 1984-03-13 1987-01-13 Nielsen J Mchenry Bifocal intra-ocular lens
US4720286A (en) * 1984-07-20 1988-01-19 Bailey Kelvin E Multifocus intraocular lens
US4759762A (en) * 1985-03-08 1988-07-26 Grendahl Dennis T Accommodating lens
US4693572A (en) * 1985-06-03 1987-09-15 Fused Kontacts Of Chicago, Inc. Monocentric bifocal corneal contact lens
US4752123A (en) * 1985-11-19 1988-06-21 University Optical Products Co. Concentric bifocal contact lens with two distance power regions
US4890912A (en) * 1986-01-24 1990-01-02 Rients Visser Trifocal eye-contact lens
US4938583A (en) * 1986-06-02 1990-07-03 Miller Gregory N Contact lens and method of making same
US5192318A (en) * 1986-06-05 1993-03-09 Schneider Richard T One-piece bifocal intraocular lens construction
US4676792A (en) * 1986-08-26 1987-06-30 Donald Praeger Method and artificial intraocular lens device for the phakic treatment of myopia
US4842601A (en) * 1987-05-18 1989-06-27 Smith S Gregory Accommodating intraocular lens and method of implanting and using same
US5201762A (en) * 1987-05-20 1993-04-13 Hauber Frederick A Intraocular archromatic lens
US4898461A (en) * 1987-06-01 1990-02-06 Valdemar Portney Multifocal ophthalmic lens
US5225858A (en) * 1987-06-01 1993-07-06 Valdemar Portney Multifocal ophthalmic lens
US5521656A (en) * 1987-06-01 1996-05-28 Portney; Valdemar Method of making an ophthalmic lens
US5657108A (en) * 1987-06-01 1997-08-12 Portney; Valdemar Multifocal ophthalmic lens
US4769033A (en) * 1987-07-02 1988-09-06 Nordan Lee T Intraocular multifocal lens
US5019099A (en) * 1987-07-02 1991-05-28 Nordan Lee T Intraocular multifocal lens method for correcting the aphakic eye
US4932968A (en) * 1987-07-07 1990-06-12 Caldwell Delmar R Intraocular prostheses
US4921496A (en) * 1987-08-24 1990-05-01 Grendahl Dennis T Radially segemented zone of focus artificial hydrogel lens
US4917681A (en) * 1987-08-24 1990-04-17 Nordan Lee T Intraocular multifocal lens
US4919663A (en) * 1987-08-24 1990-04-24 Grendahl Dennis T Laminated zone of focus artificial hydrogel lens
US4906246A (en) * 1987-08-24 1990-03-06 Grendahl Dennis T Cylindrically segmented zone of focus artificial hydrogel lens
US5047052A (en) * 1987-11-06 1991-09-10 Seymour Dubroff Anterior chamber intraocular lens with four point fixation
US5000559A (en) * 1988-02-29 1991-03-19 Nikon Corporation Ophthalmic lenses having progressively variable refracting power
US5089024A (en) * 1988-04-19 1992-02-18 Storz Instrument Company Multi-focal intraocular lens
US4923296A (en) * 1988-07-14 1990-05-08 Erickson Paul M Oriented simultaneous vision bifocal contact lenses or the like utilizing introaocular suppression of blur
US5192317A (en) * 1988-07-26 1993-03-09 Irvin Kalb Multi focal intra-ocular lens
US4830481A (en) * 1988-08-12 1989-05-16 Minnesota Mining And Manufacturing Company Multifocal diffractive lens
US4932966A (en) * 1988-08-15 1990-06-12 Storz Instrument Company Accommodating intraocular lens
US4994082A (en) * 1988-09-09 1991-02-19 Ophthalmic Ventures Limited Partnership Accommodating intraocular lens
US4990159A (en) * 1988-12-02 1991-02-05 Kraff Manus C Intraocular lens apparatus with haptics of varying cross-sectional areas
US4892543A (en) * 1989-02-02 1990-01-09 Turley Dana F Intraocular lens providing accomodation
US5019098A (en) * 1989-05-19 1991-05-28 Essilor International Cie Generale D'optique Sight-correcting optical component such as an intra-ocular implant or contact lens
US4955902A (en) * 1989-11-13 1990-09-11 Kelman Charles D Decentered intraocular lens
US5002382A (en) * 1989-12-07 1991-03-26 Leonard Seidner Multifocal corneal contact lenses
US5496366A (en) * 1990-04-27 1996-03-05 Cumming; J. Stuart Accommodating intraocular lens
US5026396A (en) * 1990-05-07 1991-06-25 Darin John J Two-piece intraocular lens
US5096285A (en) * 1990-05-14 1992-03-17 Iolab Corporation Multifocal multizone diffractive ophthalmic lenses
US5112351A (en) * 1990-10-12 1992-05-12 Ioptex Research Inc. Multifocal intraocular lenses
US5766244A (en) * 1991-05-23 1998-06-16 Binder; Helmut Intraocular artificial lens and method for fabricating same
US5652014A (en) * 1991-08-16 1997-07-29 Galin; Miles A. Medicament coated refractive anterior chamber ocular implant
US5275623A (en) * 1991-11-18 1994-01-04 Faezeh Sarfarazi Elliptical accommodative intraocular lens for small incision surgery
US5443506A (en) * 1992-11-18 1995-08-22 Garabet; Antoine L. Lens with variable optical properties
US5480428A (en) * 1993-04-22 1996-01-02 Mezhotraslevoi Nauchno-Tekhnichesky Komplex "Mikrokhirurgia Glaza" Corrective intraocular lens
US5489302A (en) * 1994-05-24 1996-02-06 Skottun; Bernt C. Accommodating intraocular lens
US5628796A (en) * 1994-07-04 1997-05-13 Suzuki; Taketoshi Intraocular lens
US5609630A (en) * 1994-08-22 1997-03-11 Philippe Crozafon Intraocular implant
US6013101A (en) * 1994-11-21 2000-01-11 Acuity (Israel) Limited Accommodating intraocular lens implant
US5549760A (en) * 1994-12-01 1996-08-27 White Consolidated Industries, Inc. Mounting device for dishwasher insulation
US6387126B1 (en) * 1995-02-15 2002-05-14 J. Stuart Cumming Accommodating intraocular lens having T-shaped haptics
US5628795A (en) * 1995-03-15 1997-05-13 Langerman David W Spare parts for use in ophthalmic surgical procedures
US5652638A (en) * 1995-05-04 1997-07-29 Johnson & Johnson Vision Products, Inc. Concentric annular ring lens designs for astigmatism
US5607472A (en) * 1995-05-09 1997-03-04 Emory University Intraocular lens for restoring accommodation and allows adjustment of optical power
US5769890A (en) * 1997-01-16 1998-06-23 Henry H. McDonald Placement of second artificial lens in eye, to correct for optical defects of first artificial lens in eye
US5769890B1 (en) * 1997-01-16 2000-09-05 Surgical Concepts Inc Placement of second artificial lens in eye to correct for optical defects of first artificial lens in eye
US6096078A (en) * 1997-10-20 2000-08-01 Surgical Concepts, Inc. Accommodative lens implantation
US5876442A (en) * 1998-01-15 1999-03-02 Visioncare Ltd. Intraocular lens implant with telescope support
US6186148B1 (en) * 1998-02-04 2001-02-13 Kiyoshi Okada Prevention of posterior capsular opacification
US6176878B1 (en) * 1998-12-17 2001-01-23 Allergan Sales, Inc. Accommodating intraocular lens
US6224628B1 (en) * 1999-04-23 2001-05-01 Thinoptx, Inc. Haptics for an intraocular lens
US6217612B1 (en) * 1999-09-10 2001-04-17 Randall Woods Intraocular lens implant having eye accommodating capabilities

Cited By (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9814570B2 (en) 1999-04-30 2017-11-14 Abbott Medical Optics Inc. Ophthalmic lens combinations
US8425597B2 (en) 1999-04-30 2013-04-23 Abbott Medical Optics Inc. Accommodating intraocular lenses
US20030078657A1 (en) * 2001-01-25 2003-04-24 Gholam-Reza Zadno-Azizi Materials for use in accommodating intraocular lens system
US6786934B2 (en) 2001-01-25 2004-09-07 Visiogen, Inc. Biasing element for intraocular lens system
US20020116057A1 (en) * 2001-01-25 2002-08-22 Ting Albert C. Optic configuration for intraocular lens system
US7226478B2 (en) * 2001-01-25 2007-06-05 Visiogen, Inc. Optic configuration for intraocular lens system
US8992609B2 (en) 2001-08-31 2015-03-31 Powervision, Inc. Intraocular lens system and method for power adjustment
US7776088B2 (en) 2001-08-31 2010-08-17 Powervision, Inc. Intraocular lens system and method for power adjustment
US7097660B2 (en) 2001-12-10 2006-08-29 Valdemar Portney Accommodating intraocular lens
US20030109926A1 (en) * 2001-12-10 2003-06-12 Valdemar Portney Accommodating intraocular lens
US9504560B2 (en) 2002-01-14 2016-11-29 Abbott Medical Optics Inc. Accommodating intraocular lens with outer support structure
US8343216B2 (en) 2002-01-14 2013-01-01 Abbott Medical Optics Inc. Accommodating intraocular lens with outer support structure
US20170020662A1 (en) * 2002-02-02 2017-01-26 John H. Shadduck Accommodating intraocular lenses
US8048155B2 (en) 2002-02-02 2011-11-01 Powervision, Inc. Intraocular implant devices
US9456895B2 (en) 2002-02-02 2016-10-04 Powervision, Inc. Accommodating intraocular lens
US8425599B2 (en) 2002-02-02 2013-04-23 Powervision, Inc. Accommodating intraocular lenses and methods of use
US9271830B2 (en) 2002-12-05 2016-03-01 Abbott Medical Optics Inc. Accommodating intraocular lens and method of manufacture thereof
US20080015689A1 (en) * 2002-12-12 2008-01-17 Victor Esch Accommodating Intraocular Lens System and Method
US20080046075A1 (en) * 2002-12-12 2008-02-21 Esch Victor C Accommodating Intraocular Lens System and Method
US9795473B2 (en) 2002-12-12 2017-10-24 Powervision, Inc. Accommodating intraocular lenses
US20070213817A1 (en) * 2002-12-12 2007-09-13 Victor Esch Accommodating intraocular lens having peripherally actuated deflectable surface and method
US8361145B2 (en) 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
US20070106377A1 (en) * 2002-12-12 2007-05-10 Powervision, Inc. Accommodating intraocular lens system having spherical aberration compensation and method
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US9277987B2 (en) 2002-12-12 2016-03-08 Powervision, Inc. Accommodating intraocular lenses
US9855137B2 (en) 2002-12-12 2018-01-02 Powervision, Inc. Accommodating intraocular lenses and methods of use
US9872762B2 (en) 2002-12-12 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
US20070010880A1 (en) * 2002-12-12 2007-01-11 Powervision, Inc. Methods of adjusting the power of an intraocular lens
US20040190153A1 (en) * 2002-12-12 2004-09-30 Powervision Lens system and method for power adjustment using externally actuated micropumps
US8454688B2 (en) 2002-12-12 2013-06-04 Powervision, Inc. Accommodating intraocular lens having peripherally actuated deflectable surface and method
US20080046074A1 (en) * 2002-12-12 2008-02-21 Smith David J Accommodating Intraocular Lens System Having Spherical Aberration Compensation and Method
US20040162612A1 (en) * 2003-02-13 2004-08-19 Valdemar Portney Accommodating intraocular lens system with enhanced range of motion
US7238201B2 (en) 2003-02-13 2007-07-03 Visiogen, Inc. Accommodating intraocular lens system with enhanced range of motion
US8303656B2 (en) 2003-03-06 2012-11-06 Powervision, Inc. Adaptive optic lens and method of making
US9198752B2 (en) 2003-12-15 2015-12-01 Abbott Medical Optics Inc. Intraocular lens implant having posterior bendable optic
US20070191941A1 (en) * 2004-06-03 2007-08-16 Burkhard Dick Capsular equatorial ring
US9872763B2 (en) 2004-10-22 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
US8377123B2 (en) 2004-11-10 2013-02-19 Visiogen, Inc. Method of implanting an intraocular lens
US9636213B2 (en) * 2005-09-30 2017-05-02 Abbott Medical Optics Inc. Deformable intraocular lenses and lens systems
US20070078515A1 (en) * 2005-09-30 2007-04-05 Brady Daniel G Deformable intraocular lenses and lens systems
US20070244560A1 (en) * 2006-04-12 2007-10-18 Alexei Ossipov Intraocular lens with distortion free valve
US20070260308A1 (en) * 2006-05-02 2007-11-08 Alcon, Inc. Accommodative intraocular lens system
US8403984B2 (en) 2006-11-29 2013-03-26 Visiogen, Inc. Apparatus and methods for compacting an intraocular lens
US20080125790A1 (en) * 2006-11-29 2008-05-29 George Tsai Apparatus and methods for compacting an intraocular lens
US8182531B2 (en) 2006-12-22 2012-05-22 Amo Groningen B.V. Accommodating intraocular lenses and associated systems, frames, and methods
US20090018652A1 (en) * 2006-12-22 2009-01-15 Amo Groningen Bv Accommodating intraocular lenses and associated systems, frames, and methods
US7871437B2 (en) 2006-12-22 2011-01-18 Amo Groningen B.V. Accommodating intraocular lenses and associated systems, frames, and methods
US8496701B2 (en) 2006-12-22 2013-07-30 Amo Groningen B.V. Accommodating intraocular lenses and associated systems, frames, and methods
US9039760B2 (en) 2006-12-29 2015-05-26 Abbott Medical Optics Inc. Pre-stressed haptic for accommodating intraocular lens
US8158712B2 (en) 2007-02-21 2012-04-17 Powervision, Inc. Polymeric materials suitable for ophthalmic devices and methods of manufacture
US9855139B2 (en) 2007-07-23 2018-01-02 Powervision, Inc. Intraocular lens delivery systems and methods of use
US8956408B2 (en) 2007-07-23 2015-02-17 Powervision, Inc. Lens delivery system
US8314927B2 (en) 2007-07-23 2012-11-20 Powervision, Inc. Systems and methods for testing intraocular lenses
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
US9610155B2 (en) 2008-07-23 2017-04-04 Powervision, Inc. Intraocular lens loading systems and methods of use
US9011532B2 (en) 2009-06-26 2015-04-21 Abbott Medical Optics Inc. Accommodating intraocular lenses
US9603703B2 (en) 2009-08-03 2017-03-28 Abbott Medical Optics Inc. Intraocular lens and methods for providing accommodative vision
US8447086B2 (en) 2009-08-31 2013-05-21 Powervision, Inc. Lens capsule size estimation
US20110071628A1 (en) * 2009-09-24 2011-03-24 Rainbow Medical Ltd. Accommodative intraocular lens
US20120310341A1 (en) * 2009-11-17 2012-12-06 Akkolens International B.V. Accommodative Intraocular Lens Driven by Ciliary Mass
US9114005B2 (en) * 2009-11-17 2015-08-25 Akkolens International B.V. Accommodative intraocular lens driven by ciliary mass
US8900298B2 (en) 2010-02-23 2014-12-02 Powervision, Inc. Fluid for accommodating intraocular lenses
US9034036B2 (en) 2010-06-21 2015-05-19 James Stuart Cumming Seamless-vision, tilted intraocular lens
US9655716B2 (en) 2010-06-21 2017-05-23 James Stuart Cumming Semi-rigid framework for a plate haptic accommodating intraocular lens
US9283070B2 (en) 2010-06-21 2016-03-15 James Stuart Cumming Vitreous compressing plate haptic
US9585745B2 (en) 2010-06-21 2017-03-07 James Stuart Cumming Foldable intraocular lens with rigid haptics
US8764823B2 (en) 2010-06-21 2014-07-01 James Stuart Cumming Semi-rigid framework for a plate haptic accommodating intraocular lens
US9211186B2 (en) 2010-06-21 2015-12-15 James Stuart Cumming Semi-rigid framework for a plate haptic intraocular lens
US9918830B2 (en) 2010-06-21 2018-03-20 James Stuart Cumming Foldable intraocular lens with rigid haptics
US9044317B2 (en) 2010-07-09 2015-06-02 Powervision, Inc. Intraocular lens delivery devices and methods of use
US9693858B2 (en) 2010-07-09 2017-07-04 Powervision, Inc. Intraocular lens delivery devices and methods of use
US8668734B2 (en) 2010-07-09 2014-03-11 Powervision, Inc. Intraocular lens delivery devices and methods of use
US9730786B2 (en) 2011-01-31 2017-08-15 James Stuart Cumming Anterior capsule deflector ridge
US8734512B2 (en) 2011-05-17 2014-05-27 James Stuart Cumming Biased accommodating intraocular lens
US9295545B2 (en) 2012-06-05 2016-03-29 James Stuart Cumming Intraocular lens
US9295544B2 (en) 2012-06-05 2016-03-29 James Stuart Cumming Intraocular lens
US9358101B2 (en) 2012-06-05 2016-06-07 James Stuart Cumming Intraocular lens
US9925039B2 (en) 2012-12-26 2018-03-27 Rainbow Medical Ltd. Accommodative intraocular lens
US9295546B2 (en) 2013-09-24 2016-03-29 James Stuart Cumming Anterior capsule deflector ridge
US9629711B2 (en) 2013-12-30 2017-04-25 James Stuart Cumming Intraocular lens
US9615916B2 (en) 2013-12-30 2017-04-11 James Stuart Cumming Intraocular lens
US9351825B2 (en) 2013-12-30 2016-05-31 James Stuart Cumming Semi-flexible posteriorly vaulted acrylic intraocular lens for the treatment of presbyopia
US9655717B2 (en) 2013-12-30 2017-05-23 James Stuart Cumming Semi-flexible posteriorly vaulted acrylic intraocular lens for the treatment of presbyopia

Also Published As

Publication number Publication date Type
DE60126489D1 (en) 2007-03-22 grant
WO2001066042A1 (en) 2001-09-13 application
DE60126489T2 (en) 2007-11-15 grant
JP2003525694A (en) 2003-09-02 application
EP1292247A1 (en) 2003-03-19 application
CA2401972A1 (en) 2001-09-13 application
US6551354B1 (en) 2003-04-22 grant
CA2401972C (en) 2009-01-20 grant
EP1292247B1 (en) 2007-02-07 grant
JP3958576B2 (en) 2007-08-15 grant

Similar Documents

Publication Publication Date Title
US5769890A (en) Placement of second artificial lens in eye, to correct for optical defects of first artificial lens in eye
US6638306B2 (en) Accommodating intraocular lens having t-shaped haptics
US5366501A (en) Intraocular lens with dual 360 degree haptics
US5776191A (en) Fixation system for intraocular lens structures
US5443506A (en) Lens with variable optical properties
US6398809B1 (en) Intraocular lens
US6280471B1 (en) Glare-free intraocular lens and method for using the same
US6152959A (en) Iris fixated intraocular lens
US6506212B2 (en) Anatomically compatible posterior chamber phakic refractive lenses
US4932971A (en) Clip-on optic assembly
US6554860B2 (en) Foldable iris fixated intraocular lenses
US5026396A (en) Two-piece intraocular lens
US6969403B2 (en) Accommodative intraocular lens
US4790847A (en) Intraocular lens implant having eye focusing capabilities
US5323788A (en) Overlapping split ring device for corneal curvature adjustment
US6478821B1 (en) Iris fixated intraocular lens and method of implantation
US20040082994A1 (en) Accommodating intraocular lens implant
US20070129803A1 (en) Accommodative Intraocular Lens
US4892543A (en) Intraocular lens providing accomodation
US6197057B1 (en) Lens conversion system for teledioptic or difractive configurations
US7985253B2 (en) Hydrolic accommodating intraocular lens
US4880427A (en) Flexible posterior chamber lens
US20040006387A1 (en) Intraocular lens
US20030187505A1 (en) Accommodating intraocular lens with textured haptics
US6228115B1 (en) Intraocular lenses with improved axial stability

Legal Events

Date Code Title Description
AS Assignment

Owner name: ADVANCED MEDICAL OTPICS, INC., CALIFORNIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:ALLERGAN, INC.;ALLERGAN SALES, LLC;ALLERGAN PHARMACEUTICALS, INC.;AND OTHERS;REEL/FRAME:014217/0356

Effective date: 20030625