New! View global litigation for patent families

US20030018390A1 - Intervertebral prosthesis - Google Patents

Intervertebral prosthesis Download PDF

Info

Publication number
US20030018390A1
US20030018390A1 US09499274 US49927400A US2003018390A1 US 20030018390 A1 US20030018390 A1 US 20030018390A1 US 09499274 US09499274 US 09499274 US 49927400 A US49927400 A US 49927400A US 2003018390 A1 US2003018390 A1 US 2003018390A1
Authority
US
Grant status
Application
Patent type
Prior art keywords
spiral
body
elastic
form
implant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
US09499274
Other versions
US6610094B2 (en )
Inventor
Jean-Louis Husson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zimmer GmbH
Original Assignee
Jean-Louis Husson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32Surgical cutting instruments
    • A61B17/3201Scissors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2/4611Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/0046Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable
    • A61B2017/00469Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable for insertion of instruments, e.g. guide wire, optical fibre
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/3008Properties of materials and coating materials radio-opaque, e.g. radio-opaque markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30224Three-dimensional shapes cylindrical
    • A61F2002/30225Flat cylinders, i.e. discs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30291Three-dimensional shapes spirally-coiled, i.e. having a 2-D spiral cross-section
    • A61F2002/30293Cylindrical body made by spirally rolling up a sheet or a strip around itself
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30565Special structural features of bone or joint prostheses not otherwise provided for having spring elements
    • A61F2002/305732-D spiral springs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2002/4415Joints for the spine, e.g. vertebrae, spinal discs elements of the prosthesis being arranged in a chain like manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • A61F2002/444Intervertebral or spinal discs, e.g. resilient for replacing the nucleus pulposus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4622Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof having the shape of a forceps or a clamp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4625Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
    • A61F2002/4627Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about the instrument axis or the implantation direction, e.g. telescopic, along a guiding rod, screwing inside the instrument
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4625Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
    • A61F2002/4628Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about an axis transverse to the instrument axis or to the implantation direction, e.g. clamping
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0091Three-dimensional shapes helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0098Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00011Metals or alloys
    • A61F2310/00023Titanium or titanium-based alloys, e.g. Ti-Ni alloys
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S606/00Surgery
    • Y10S606/907Composed of particular material or coated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S606/00Surgery
    • Y10S606/907Composed of particular material or coated
    • Y10S606/91Polymer

Abstract

The invention deals with an implant, in particular, an intervertebral prosthesis, which consists of an elongated elastic body which is form-elastic and takes on the form of a spiral S in the force-free state. The spiral can be drawn by a reverse winding up into an insertion instrument which is only unsubstantially larger in the insertion region than the cross-section of the elongated elastic body in order to reach the inner space of an intervertebral disc through a small opening in the annulus fibrosus and to push in and sever off the self-winding spiral when the interior is filled. This has the advantage that inner spaces of differing sizes can be filled with the same spiral.

Description

    CROSS-REFERENCES TO RELATED APPLICATIONS
  • [0001]
    This application is a continuation-in-part application and claims priority from U.S. patent application Ser. No. 09/249,945 filed Feb. 12, 1999; and U.S. patent application Ser. No. 09/249,934 filed Feb. 12, 1999 both of which are divisional applications and claim priority from U.S. patent application Ser. No. 08/723,146, filed Sep. 30, 1996; the disclosures of which are incorporated herein by reference.
  • BACKGROUND OF THE INVENTION
  • [0002]
    1. Field of the Invention
  • [0003]
    The invention relates to an implant, in particular an intervertebral prosthesis, consisting of an elongated elastic body.
  • [0004]
    2. Description of the Prior Art
  • [0005]
    A prosthesis of this type is known from EP-A-O 453 393. It serves as replacement for a damaged intervertebral disc nucleus (nucleus pulposus). The outer ring (annulus fibrosus) of a natural intervertebral disc remains intact for the most part. The known prosthesis consists of a fluid-tight hollow body which is filled with an incompressible flowable medium. This prosthesis requires for its implantation a specially formed insertion instrument by means of which the hollow body is intraoperatively coiled up into a spiral form and can subsequently be filled. This places high demands on the skill of the surgeon on the one hand, as well as on the manufacture of the insertion instrument with respect to the coiling mechanism, as well as with regard to the filling apparatus. Furthermore, the leak-proofing criteria of the hollow body represent a long-term risk when the great stresses in the region of the vertebral column are taken into account. After the body has been rolled up in the intervertebral region and filled, the free end lies in contact with the annulus fibrosus, if the tool which acts at the center of the spiral for filling and sealing is removable without producing cavities. Only if no migration of spiral elements into other cavities can occur can the radially directed forces arising under the stress be compensated for and the spiral achieve the desired support function.
  • SUMMARY OF THE INVENTION
  • [0006]
    The object of the invention is to provide an implant which permits a simple handling.
  • [0007]
    This object is satisfied by an implant in accordance with the present invention, which comprises an elongated elastic body which is form-elastic and takes on the form of a spiral in the force-free state. The cross-section of the body is preferably rectangular, and the edges can also be rounded off. It is also possible to use bodies with a roundish cross-section as long as an essentially form-fitted, tilt-proof position of the spiral is retained under load. The cross-section of the elastic body need not be constant over its entire length, but rather it turns out that its thickness can preferably decrease in the outward direction. Such a spiral has the advantage that it winds itself, does not bend when thrust in, and can be severed at a suitable rolled-up length.
  • [0008]
    The implant as such can take the form of a cylindrical disc, i.e. can be made flat, or else can have inward and/or outward curvatures which follow the contours of the vertebral surfaces. In this way, the forces produced under load can be more uniformly distributed over the vertebral surfaces. The diameter of the spiral is preferably chosen such that the space within the annulus fibrosus is filled out.
  • [0009]
    In order to insert the intervertebral disc it has proved advantageous to attach a stiffening means in the form of a plastic or metal band at the free end of the spiral via which a severing device can be guided up to a desired point of severance. The band preferably has no curvature in the force-free state. After a successful implantation the band is severed off from the implanted spiral along with that portion of the spiral not required by means of the severing device.
  • [0010]
    In order to be able to check the location of the implant intraoperatively and postoperatively, it is recommendable to provide X-ray-positive markings in the form of spheres or of a thread on or along the inside of the elastic body.
  • [0011]
    The material of which the elastic body is manufactured should correspond essentially to the elastic properties of an intervertebral disc so that the forces arising are as far as possible transmitted uniformly to the vertebral surface. The use of polyurethane or polyurethane-silicon mixtures, which have a Shore hardness of approximately BOA, has proved advantageous. Foams of the most diverse plastics can also be used as long as they satisfy the elastic requirements.
  • [0012]
    In an especially preferred embodiment, the spiral has a central middle part about which the further turns wrap themselves closely. Only small intervening spaces arise, which fill up with intervertebral fluid in the implanted state where present and which do not permit a canting of the elastic body under radial forces. By means of a suitable height to width relationship a canting of the elastic body is prevented in general. The middle piece can basically have the form of a circular cylinder, but forms such as a sphere or ellipsoid have also proved useful. It is advantageous that a short, thin transition part be joined thereto via which the connection to the remaining spiral is established. This has the advantage that the spiral remains in the tightest surface-surface packing and the greatest possible area distribution is achieved while eliminating force peaks. In a simpler embodiment of the implant the central middle piece can also be dispensed with since the contribution of its area is small in comparison with the total area.
  • [0013]
    The height of the spiral corresponds essentially to the physiological intervertebral spacing. The preferred thickness with which the elastic body is to be executed results from the elastic properties of the material used. At the periphery of the spiral, after about three to five turns, depending on the material and the breadth of the turn, the thickness of the body can decrease since the applied forces should be primarily taken up centrally and since on the other hand the body should be capable of being severed at a corresponding position. In a further embodiment of the invention it is possible to adapt the height of the implant to the individual intervertebral spacings.
  • [0014]
    The severance should preferably take place inside the cavity, for which purpose the corresponding forces must be supplied by means of an instrument to be described in further detail.
  • [0015]
    The invention also relates to a process for manufacturing an intervertebral implant in the form of a spiral. For this purpose the implant can, in the simplest case, be cut out e.g. of a material plate of the corresponding thickness. Conventional saws, cutting wires or similar tools can be used as the cutting means. Lasers which are suitable for cutting plastics can, however, also be used. In particular, lasers such as the excimer lasers, which permit a thermal cutting, are advantageous here, since they avoid for the most part the production of toxic by-products. An especially preferred process is the injection molding process, with the injection into the snail-shaped mold preferably taking place at the interior of the spiral. The implant thus obtained has a spiral form with tightly form-fitted turns.
  • [0016]
    The invention relates further to an apparatus for inserting the implant, which essentially has a tube with a rectangular cross-section into which the elastic body can be drawn in, and preferably so far that the middle piece just protrudes from the distal end of the tube. The cross-section of the tube corresponds essentially to the cross-section of the elastic body. The feeding of the body can be done by hand. However, feeding means in the form of a pusher tool which can be activated, e.g. via a lever mechanism, are preferably provided, together with a corresponding cross-sectional enlargement of the tube. The pusher tool has means at its distal end, standing in operative contact with the elastic body or the stiffening, which facilitate the feeding of the body. The means can consist of a roughening of the surface, or else of tooth-like projections with preferential orientation in the distal direction. This achieves a situation in which the extensions grip into the elastic body or the stiffening on advance of the pusher tool and push the latter along with the pusher tool, whereas they slide backwards over the surface on retraction of the pusher tool. A controlled feeding of the elastic body is thereby made possible. It is of additional advantage to provide the tube at its distal end with a one-sided narrowing of its cross-section which at its narrow end is just capable of taking up the elastic body only. This has the effect that the pusher tool, when pushed forward, is simultaneously pushed downward, and thus the force transmitting contact between the pusher tool and the body is increased.
  • [0017]
    The tube of the insertion apparatus can advantageously be curved as well, since the insertion of an implant into the intervertebral space is preferably done from the side dorsally. The curvature can be executed either upwards or downwards, or if desired, to the left or the right, depending on which side the access is desired to occur. Here, the insertion apparatus can also run out at the forward end in a wedge in order to adequately space neighboring vertebral bodies which have lost their separation by means of the wedge-formed part.
  • [0018]
    The invention relates further to an apparatus for cutting off the end of the spiral which is not required. After the intervertebral prosthesis has been implanted, the insertion apparatus is pulled back along the stiffening, which at least partially remains outside of the intervertebral region, and the cut-off instrument is pushed onto it. This instrument preferably has an action mechanism similar to a pair of pliers, and comprises two grip parts standing in contact with one another via a hinge. One jaw of the cutting part is executed to be hollow so that it can receive the stiffening. The other jaw has a cutting edge standing essentially transversely to the longitudinal axis of the pliers. The length of the jaws as well as the placement of the cutting edge in the distal direction are preferably chosen in such a manner that, on the one hand, a cut in the intervertebral region is possible, and on the other hand, that the required severance forces can be safely exerted. Here the elastic body is enclosed in such a manner that no foreign tissue parts are cut when the end of the spiral not required is cut off. Of course pliers whose grip parts stand at an angle to the longitudinal axis can also be used in accordance with the invention.
  • [0019]
    In an especially preferred embodiment the insertion apparatus can also contain a cutting instrument. This can be realized, for example, by providing a further pusher tool with a cutting blade at its distal end which extends perpendicular to the longitudinal axis of the apparatus. The cutting action is produced by the distal narrowing of the tube cross-section, in a manner similar to the feeding situation.
  • [0020]
    In an alternative embodiment, an implant is provided that consists of an elongated, elastic body that is form-elastic and that takes on the form of a spiral in the force-free state, wherein a hydrogel member is affixed to the body in a dehydrated state and has the possibility to enlarge its volume after implantation. In accordance with one embodiment, the hydrogel members are held in grooves at the bottom or at the sides of the body and follow the spiral.
  • [0021]
    In another embodiment, the hydrogel bodies extend at the bottom or at the top surface of the body.
  • [0022]
    In yet a further embodiment, the hydrogel members are in a sandwich structure with one or several bodies in the form of a spiral.
  • [0023]
    In yet another embodiment, a bond is included between the hydrogel member and the body.
  • [0024]
    In another embodiment, a hydrogel tube surrounds the body.
  • [0025]
    Thus, the present invention provides an implant that has the advantage of being as simple as possible in its construction and of ensuring a supporting effect uniformly over a greater part of its area. The implant has the further advantage of not having to be fixed in a spiral form by additional means, but can be inserted with comparatively simple and easy to use instruments.
  • [0026]
    The present invention relates further to a process for inserting a spiral implant into a cavity as can be used for the purposes of teaching, practice and demonstration.
  • [0027]
    In the following the invention will be explained on the basis of especially preferred exemplary embodiments in connection with the drawings.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0028]
    [0028]FIG. 1 shows schematically a greatly enlarged elastic body in the form of a spiral;
  • [0029]
    [0029]FIG. 2 shows a cross-section through the spiral of FIG. 1;
  • [0030]
    [0030]FIG. 3 shows a schematic representation of an insertion apparatus;
  • [0031]
    [0031]FIG. 4 shows a schematic representation of a severing apparatus;
  • [0032]
    [0032]FIG. 5 shows a schematic plan view of the severing apparatus of FIG. 4;
  • [0033]
    FIGS. 6-14 schematically illustrate enlarged cross-sections of a spiral body in accordance with an alternative embodiment of the present invention;
  • [0034]
    FIGS. 15-17 schematically illustrate enlarged cross-sections of various arrangements of the alternative embodiments illustrated in FIGS. 7-14;
  • [0035]
    [0035]FIG. 18 schematically illustrates the alternative embodiment arrangement illustrated in FIG. 15; and
  • [0036]
    [0036]FIG. 19 schematically illustrates the alternative embodiment arrangement illustrated in FIG. 6.
  • DETAILED DESCRIPTION OF THE PREFERRED EXEMPLARY EMBODIMENTS
  • [0037]
    The figures deal with an implant, in particular an intervertebral prosthesis preferably of an elongated elastic body, which is form-elastic and takes on the form of a spiral S in the force-free state. The spiral can be drawn by reverse winding up into an insertion instrument, which is only insubstantially larger in the insertion region than the cross-section of the elongated elastic body in order to reach the inner space of an intervertebral disc through a small opening in the annulus fibrosus and to push in and separate off the self-winding spiral when the inner space is filled. This has the advantage that inner spaces of differing sizes can be filled with the same spiral.
  • [0038]
    [0038]FIG. 1 shows the spiral implant with a central middle part 1, which has essentially the form of a cylinder. This is joined at the side by a thin region 2 which permits a pronounced angular deflection and thus a form-fitted transition to the spiral turn 3 connected to it, essentially without intervening spaces.
  • [0039]
    In the case that the middle piece is absent it is recommendable to execute the inner end of the spiral turn in such a manner that no tension peaks can occur under stress. This can be achieved, for example, by means of a rounded-off end.
  • [0040]
    The spiral turns connected to the transition region are form-fitted and have a constant breadth in the region of 2 to 5 mm so that canting under the loads to be expected can be excluded to the greatest extent. The implant comprises preferably 2-4 turns which are proof against canting. This is followed by a transition region 4 in which the breadth of the elastic body is reduced to such an extent that an easy separation is possible, e.g. in about the region 5 of FIG. 1. The spiral is adjusted intra-operatively to the desired size through the number of turns. The support effect in respect to tilting is reduced per se in the outer turns, however it is sufficiently great in connection with the more form-stable inner turns.
  • [0041]
    The thickness of the elastic body which forms the spiral can however also decrease steadily from the inside outwards, so that no specially executed transition region is required. In FIG. 2 the spiral is shown in cross-section. It has a diameter in the range of 20 to 30 mm, preferably in the range from 23 to 25.5 mm. The height preferably amounts to 5-10 mm. The height can also increase continually in the direction of the center and take on a maximum of 10 mm at the center. The height can also be adapted to the individual curvature of the vertebral surfaces, which can be especially of interest in the case of vertebral deformations.
  • [0042]
    A band-like stiffening 7 is fixed to the free end of the spiral 6 and projects beyond the free end so as to serve as an extension when handling the spiral. The transition should be as smooth as possible. The band should be capable of transmitting its shear forces and is preferably made of titanium for reasons of biocompability and sterilization. It is practical for its length to extend to approximately 20 cm, and it enables a guidance of the separation instrument up to the point of severance on the spiral.
  • [0043]
    The elastic body consists preferably of a plastic such as polyurethane with the spiral turns coming to lie form-fitted to the greatest extent in the absence of external forces. The elastic properties of the material must be such that the spiral form is again assumed even after it has been unrolled. The deformation properties of the material should be as similar to those of the intervertebral disc as possible and lie advantageously in the range of Shore hardness from about 70A to 90A, preferably around BOA. The elastic body can be manufactured by being cut out of the material, which is possible in particular with the use of computer-guided lasers. Cutting processes which do not stress the material thermally are preferable, since this avoids toxic by-products and has no influence on the elastic properties of the material. It needs no special mention that the material itself should be sterilizable.
  • [0044]
    In order to check on the position of the implant intra-operatively and postoperatively it is recommended to provide X-ray-positive markers in the form of points 8 or of a thread, which is not shown, on or along and within the elastic body. Barium, tantalum or the like can be used as the marker material.
  • [0045]
    The apparatus for inserting the elastic body is shown in more detail in FIG. 3. It comprises a rectangular tube 10 for receiving the spiral which is rolled up at least so far that its still protruding portion S can be inserted through the operatively created opening into the intervertebral region without problem. The hollow tube 10 preferably has a one-sided cross-section narrowing 11 at the distal end which is formed in the shape of a cone or a beak. The tube can also have a curvature, which eases the access to the intervertebral region from the side dorsally and is selected to match the hand preference of the user. The curvature can also be directed caudally or cranially depending on the requirements.
  • [0046]
    The feeding of the body can also be done by hand. Gripping means to support the tube are helpful for this purpose. They can be formed coaxial with the tube in the form of a thickened portion or can extend radially to the tube axis. Preferably, however, feed means are provided in the form of an elastic pusher tool 12, which can, for example, be operated via a lever mechanism 13. At its distal end, and standing in effective connection with the elastic body or with the stiffening, the pusher tool has means 14 which facilitate the feeding of the body. The means can consist of a roughening of the surface or else in tooth-like extensions with preferential orientation in the distal direction. By this means it can be achieved that when the pusher tool is pushed forward, the extensions engage the elastic body or the stiffening and push it along, whereas they glide over the surface when the pusher tool is retracted, making possible a controlled feeding of the elastic body. The one-sided cross-sectional narrowing 11 of the rectangular tube 10 causes the pusher tool to be pressed downwards at the same time as it is being pushed forwards, and thus strengthens the grip between the pusher tool and the body. Due to the fact that the pusher tool grips the unrolled spiral very far forward, the latter is practically drawn through the hollow tube, so that it does not block itself due to its own stress, as could easily be the case when the thrust is from the rear.
  • [0047]
    [0047]FIGS. 4 and 5 show an apparatus for severing off the superfluous end of the spiral. After the intervertebral prosthesis has been implanted the insertion apparatus is drawn back along the stiffening 7, which remains outside the intervertebral region, and the separation instrument 20 pushed onto it. This instrument preferably has an action mechanism similar to a pair of pliers, comprising two grip parts 21, 22 which are connected to one another via a hinge 23. One jaw 24 is provided with a recess 25 in the longitudinal direction into which the stiffening 7 and/or the elastic body 5, 6 can be taken up. The other jaw 26 has a cutting edge 27 which is movable essentially transversely to the recess 25. The length of the jaws as well as the placement of the cutting edge in the distal direction is preferably chosen in such a manner that, on the one hand, a cut within the intervertebral region is possible and, on the other hand, that the required separation forces can be applied safely. The cutting blade itself can be executed as a replaceable blade. Of course pliers whose grip parts meet the longitudinal axis at an angle can also be used in accordance with the invention.
  • [0048]
    After the elastic body is shortened to the desired length the severing apparatus is drawn back along with the stiffening 7. The implant takes on the spiral form due to its form-stable properties. The implant retains its spiral form even under load without a special fastening of the free end being necessary.
  • [0049]
    The previously described process for inserting a spiral implant into a cavity can also be advantageously used for purposes of teaching, practice or demonstration.
  • [0050]
    In an alternative embodiment, hydrogel members 28, 29 are affixed to the body 3, which takes on the form of a spiral S in the force-free state. By introducing these hydrogel members 28, 29 into the cavity of an intervertebral disc in a dehydrated and shrunken state, the body 3 takes on the form of a spiral after insertion. The hydrogel members 28, 29 take water from the human body and swell to a predetermined size. The spiral body 3 therefore may have a smaller height H than the cavity, into which it is placed for taking the form of a spiral S, but still completely fill the cavity, when the hydrogel members 28, 29 have reached their final dimensions.
  • [0051]
    FIGS. 6 to 14 schematically show enlarged cross-sections of a spiral body 3 where a hydrogel member 28, 29 is placed as a spiral at one or both sides of the spiral body 3. In FIGS. 6, 7, 8, 10 and 11 the hydrogel members 28, 29 are inserted in grooves 30 at the top or bottom side of the spiral body 3. The hydrogel members 28, 29 also have the form of a spiral with a contact surface similar to a dove tail, which is held back by the spiral body 3. In FIG. 7 the hydrogel member 28 is additionally shown with phantom lines, which show it in a swollen state. The hydrogel member 28 has the shape of a bar, which is imbedded in the spiral body 3 and which follows the spiral. FIG. 19 schematically shows a view of an arrangement according to FIG. 6 at a small scale. The spiral body 3 has hydrogel members 28, 29 at the top and at the bottom side, which are dehydrated and which will grow with the presence of water to a predetermined size.
  • [0052]
    In FIGS. 9, 12, 13, and 14 there is an additional bond 31 between spiral body 3 and hydrogel members 28, 29. In FIGS. 12 and 14 the hydrogel members are at the bottom and at the top side. In FIGS. 12 and 13 there is a sandwich structure with hydrogel members 28, 29 being arranged intermediately. Such flat structures require a good bond 31. One example of such a bond 31 is an ultrasonic weld.
  • [0053]
    In FIGS. 15 and 17 the hydrogel members 28, 29 are implanted like posts in the spiral body and extend at the bottom and at the top surface. FIG. 18 schematically shows a view of an arrangement according to FIG. 15 at a small scale. The hydrogel members 28 perforate the spiral body 3 completely.
  • [0054]
    In FIG. 16 the spiral body 3 is completely surrounded by a hydrogel member 28, which takes the form of a tube.
  • [0055]
    The hydrogel members 28, 29 may be crosslinked gel form encapsulated in a semi-permeable membrane, which follows the growth of the gel. Those skilled in the art will realize that the material of the hydrogel members 28, 29 must be biocompatible.

Claims (7)

    What is claimed is:
  1. 1. An implant consisting of an elongated, elastic body which is form-elastic and which takes on the form of a spiral in the force-free state, whereby a hydrogel member which is affixed to the body in a dehydrated state has the possibility to enlarge its volume after implantation.
  2. 2. An implant in accordance with claim 1 wherein the hydrogel members are held in grooves at the bottom or at the side of the body and which follow the spiral.
  3. 3. An implant in accordance with claim 1 wherein the hydrogel members extend at the bottom or at the top surface of the body.
  4. 4. An implant in accordance with claim 1 wherein the hydrogel members are in a sandwich structure with one or several bodies in the form of a spiral.
  5. 5. An implant in accordance with claim 1 wherein a bond is provided between the hydrogel member and the body.
  6. 6. An implant in accordance with claim 1 wherein a hydrogel tube surrounds the body.
  7. 7. An implant in accordance with claim 1 wherein the implant is an intervertebral prosthesis.
US09499274 1995-11-08 2000-02-07 Intervertebral prosthesis Expired - Fee Related US6610094B2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
EP95810701 1995-11-08
EP95810701.3 1995-11-08
EP19950810701 EP0773008B2 (en) 1995-11-08 1995-11-08 Intervertebral prosthesis
US08723146 US5919235A (en) 1995-11-08 1996-09-30 Intervertebral prosthesis
US09249945 US6660037B1 (en) 1995-11-08 1999-02-12 Intervertebral prosthesis
US09249934 US6165218A (en) 1995-11-08 1999-02-12 Intervertebral prosthesis
US09499274 US6610094B2 (en) 1995-11-08 2000-02-07 Intervertebral prosthesis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09499274 US6610094B2 (en) 1995-11-08 2000-02-07 Intervertebral prosthesis

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US09249945 Continuation-In-Part US6660037B1 (en) 1995-11-08 1999-02-12 Intervertebral prosthesis

Publications (2)

Publication Number Publication Date
US20030018390A1 true true US20030018390A1 (en) 2003-01-23
US6610094B2 US6610094B2 (en) 2003-08-26

Family

ID=27838231

Family Applications (4)

Application Number Title Priority Date Filing Date
US08723146 Expired - Lifetime US5919235A (en) 1995-11-08 1996-09-30 Intervertebral prosthesis
US09249945 Expired - Fee Related US6660037B1 (en) 1995-11-08 1999-02-12 Intervertebral prosthesis
US09249934 Expired - Lifetime US6165218A (en) 1995-11-08 1999-02-12 Intervertebral prosthesis
US09499274 Expired - Fee Related US6610094B2 (en) 1995-11-08 2000-02-07 Intervertebral prosthesis

Family Applications Before (3)

Application Number Title Priority Date Filing Date
US08723146 Expired - Lifetime US5919235A (en) 1995-11-08 1996-09-30 Intervertebral prosthesis
US09249945 Expired - Fee Related US6660037B1 (en) 1995-11-08 1999-02-12 Intervertebral prosthesis
US09249934 Expired - Lifetime US6165218A (en) 1995-11-08 1999-02-12 Intervertebral prosthesis

Country Status (5)

Country Link
US (4) US5919235A (en)
EP (2) EP0773008B2 (en)
JP (1) JP3944753B2 (en)
DE (2) DE59511075D1 (en)
ES (2) ES2211895T5 (en)

Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030229397A1 (en) * 2001-12-28 2003-12-11 Davis Reginald J. Pseudo arthrosis device
US20050015152A1 (en) * 2003-07-15 2005-01-20 Spinal Generations Spinal disc prosthesis system
US20050071007A1 (en) * 2003-09-30 2005-03-31 Malek Michel H. Intervertebral disc prosthesis
US20060129242A1 (en) * 2001-12-28 2006-06-15 Brian Bergeron Pseudo arthrosis device
US20060136064A1 (en) * 2003-06-02 2006-06-22 Sherman Michael C Intervertebral disc implants and methods for manufacturing and using the same
US20070055274A1 (en) * 2005-06-20 2007-03-08 Andreas Appenzeller Apparatus and methods for treating bone
US7267687B2 (en) 2001-10-02 2007-09-11 Rex Medical, L.P Spinal implant and method of use
US20080009943A1 (en) * 2006-06-29 2008-01-10 Depuy Spine, Inc. Insert for nucleus implant
US20080015698A1 (en) * 2002-10-31 2008-01-17 Marino James F Spinal disc implant
US20080133012A1 (en) * 2006-11-16 2008-06-05 Mcguckin James F Spinal implant and method of use
US20080314593A1 (en) * 2001-04-24 2008-12-25 Shell Oil Company In situ thermal processing of an oil shale formation using a pattern of heat sources
US20090177207A1 (en) * 2005-08-16 2009-07-09 Laurent Schaller Method of interdigitating flowable material with bone tissue
US20100121378A1 (en) * 2008-11-10 2010-05-13 Malek Michel H Facet fusion system
US7905922B2 (en) 2006-12-20 2011-03-15 Zimmer Spine, Inc. Surgical implant suitable for replacement of an intervertebral disc
US7935133B2 (en) 2008-02-08 2011-05-03 Mmsn Limited Partnership Interlaminar hook
US20110166602A1 (en) * 2006-07-28 2011-07-07 Malek Michel H Bone anchor device
US20110208308A1 (en) * 2006-11-28 2011-08-25 Columna Pty Ltd Tissue prosthesis insertion system and method
US20120221107A1 (en) * 2007-07-07 2012-08-30 Jmea Corporation Disk Fusion Implant
US20120277862A1 (en) * 2008-04-04 2012-11-01 Clariance Nuclear implant
US8366773B2 (en) 2005-08-16 2013-02-05 Benvenue Medical, Inc. Apparatus and method for treating bone
US8454617B2 (en) 2005-08-16 2013-06-04 Benvenue Medical, Inc. Devices for treating the spine
US8486113B2 (en) 2003-11-25 2013-07-16 Michel H. Malek Spinal stabilization systems
US8535327B2 (en) 2009-03-17 2013-09-17 Benvenue Medical, Inc. Delivery apparatus for use with implantable medical devices
US8591583B2 (en) 2005-08-16 2013-11-26 Benvenue Medical, Inc. Devices for treating the spine
US8617214B2 (en) 2008-01-07 2013-12-31 Mmsn Limited Partnership Spinal tension band
US8814873B2 (en) 2011-06-24 2014-08-26 Benvenue Medical, Inc. Devices and methods for treating bone tissue
US20140257417A1 (en) * 2005-08-16 2014-09-11 Spinecell Private Limited Systems, methods and apparatuses for formation and insertion of tissue prosthesis
US20140277464A1 (en) * 2013-03-14 2014-09-18 Synthes Usa, Llc Expandable coil spinal implant
US9289240B2 (en) 2005-12-23 2016-03-22 DePuy Synthes Products, Inc. Flexible elongated chain implant and method of supporting body tissue with same
US9301787B2 (en) 2010-09-27 2016-04-05 Mmsn Limited Partnership Medical apparatus and method for spinal surgery
US9492214B2 (en) 2008-12-18 2016-11-15 Michel H. Malek Flexible spinal stabilization system
US9572676B2 (en) 2013-03-14 2017-02-21 DePuy Synthes Products, Inc. Adjustable multi-volume balloon for spinal interventions
US9585761B2 (en) 2013-03-14 2017-03-07 DePuy Synthes Products, Inc. Angulated rings and bonded foils for use with balloons for fusion and dynamic stabilization
US9788963B2 (en) 2003-02-14 2017-10-17 DePuy Synthes Products, Inc. In-situ formed intervertebral fusion device and method
US9901457B2 (en) 2014-10-16 2018-02-27 Jmea Corporation Coiling implantable prostheses

Families Citing this family (174)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6113640A (en) * 1997-06-11 2000-09-05 Bionx Implants Oy Reconstructive bioabsorbable joint prosthesis
US6692499B2 (en) 1997-07-02 2004-02-17 Linvatec Biomaterials Oy Surgical fastener for tissue treatment
DE69714035D1 (en) 1997-08-14 2002-08-22 Sulzer Innotec Ag Composition and apparatus for the repair of cartilage tissue in vivo comprising nanocapsules with osteoinductive and / or chondroinductive factors
CA2326125A1 (en) 1998-04-01 1999-10-07 Bionx Implants Oy Bioabsorbable surgical fastener for tissue treatment
CA2248592A1 (en) * 1998-08-31 2000-02-29 Christopher D. Batich Microspheres for use in the treatment of cancer
US6146422A (en) * 1999-01-25 2000-11-14 Lawson; Kevin Jon Prosthetic nucleus replacement for surgical reconstruction of intervertebral discs and treatment method
US20060247665A1 (en) 1999-05-28 2006-11-02 Ferree Bret A Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US20070038231A1 (en) 1999-05-28 2007-02-15 Ferree Bret A Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US7273497B2 (en) 1999-05-28 2007-09-25 Anova Corp. Methods for treating a defect in the annulus fibrosis
US6520996B1 (en) 1999-06-04 2003-02-18 Depuy Acromed, Incorporated Orthopedic implant
WO2001001895A1 (en) * 1999-07-02 2001-01-11 Petrus Besselink Reinforced expandable cage
NL1012719C1 (en) 1999-07-28 2001-01-30 Veldhuizen Dr Ag Spinal prosthesis.
US7998213B2 (en) 1999-08-18 2011-08-16 Intrinsic Therapeutics, Inc. Intervertebral disc herniation repair
US6821276B2 (en) * 1999-08-18 2004-11-23 Intrinsic Therapeutics, Inc. Intervertebral diagnostic and manipulation device
US7553329B2 (en) 1999-08-18 2009-06-30 Intrinsic Therapeutics, Inc. Stabilized intervertebral disc barrier
US20040044412A1 (en) * 1999-08-18 2004-03-04 Gregory Lambrecht Devices and method for augmenting a vertebral disc
US7717961B2 (en) 1999-08-18 2010-05-18 Intrinsic Therapeutics, Inc. Apparatus delivery in an intervertebral disc
US7220281B2 (en) 1999-08-18 2007-05-22 Intrinsic Therapeutics, Inc. Implant for reinforcing and annulus fibrosis
WO2002054978A3 (en) 1999-08-18 2002-11-07 Intrinsic Therapeutics, Inc. Devices and method for nucleus pulposus augmentation and retention
US6425919B1 (en) 1999-08-18 2002-07-30 Intrinsic Orthopedics, Inc. Devices and methods of vertebral disc augmentation
US6936072B2 (en) * 1999-08-18 2005-08-30 Intrinsic Therapeutics, Inc. Encapsulated intervertebral disc prosthesis and methods of manufacture
EP1624832A4 (en) 1999-08-18 2008-12-24 Intrinsic Therapeutics Inc Devices and method for augmenting a vertebral disc nucleus
US20040024465A1 (en) * 1999-08-18 2004-02-05 Gregory Lambrecht Devices and method for augmenting a vertebral disc
US8679180B2 (en) * 1999-10-08 2014-03-25 Anova Corporation Devices used to treat disc herniation and attachment mechanisms therefore
US20030040796A1 (en) * 1999-10-08 2003-02-27 Ferree Bret A. Devices used to treat disc herniation and attachment mechanisms therefore
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6740093B2 (en) 2000-02-28 2004-05-25 Stephen Hochschuler Method and apparatus for treating a vertebral body
WO2001070144A1 (en) * 2000-03-22 2001-09-27 Scolio Gmbh Cage-type intervertebral implant
US6689125B1 (en) 2000-04-04 2004-02-10 Spinalabs, Llc Devices and methods for the treatment of spinal disorders
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
US6402750B1 (en) 2000-04-04 2002-06-11 Spinlabs, Llc Devices and methods for the treatment of spinal disorders
US6723335B1 (en) 2000-04-07 2004-04-20 Jeffrey William Moehlenbruck Methods and compositions for treating intervertebral disc degeneration
ES2244575T3 (en) * 2000-05-26 2005-12-16 Zimmer Gmbh An intervertebral disc replacement for the core of an intervertebral disc.
US6533817B1 (en) 2000-06-05 2003-03-18 Raymedica, Inc. Packaged, partially hydrated prosthetic disc nucleus
US7056321B2 (en) 2000-08-01 2006-06-06 Endius, Incorporated Method of securing vertebrae
US7985247B2 (en) 2000-08-01 2011-07-26 Zimmer Spine, Inc. Methods and apparatuses for treating the spine through an access device
US20020026244A1 (en) * 2000-08-30 2002-02-28 Trieu Hai H. Intervertebral disc nucleus implants and methods
US7503936B2 (en) * 2000-08-30 2009-03-17 Warsaw Orthopedic, Inc. Methods for forming and retaining intervertebral disc implants
ES2303972T3 (en) * 2000-08-30 2008-09-01 Warsaw Orthopedic, Inc. Intervertebral disc implants.
US7204851B2 (en) * 2000-08-30 2007-04-17 Sdgi Holdings, Inc. Method and apparatus for delivering an intervertebral disc implant
US20050154463A1 (en) * 2000-08-30 2005-07-14 Trieu Hal H. Spinal nucleus replacement implants and methods
US6620196B1 (en) 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
WO2002026170A3 (en) * 2000-09-26 2003-01-16 Lionel C Sevrain Inter-vertebral disc prosthesis for lumbar rachis through posterior surgery thereof
US6579291B1 (en) 2000-10-10 2003-06-17 Spinalabs, Llc Devices and methods for the treatment of spinal disorders
CA2323252C (en) * 2000-10-12 2007-12-11 Biorthex Inc. Artificial disc
US6974480B2 (en) 2001-05-03 2005-12-13 Synthes (Usa) Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
US6719794B2 (en) 2001-05-03 2004-04-13 Synthes (U.S.A.) Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
US6736848B2 (en) 2001-05-29 2004-05-18 Sdgi Holdings, Inc. Method and apparatus for using formable polymers for orthopedic support
US20040220669A1 (en) * 2001-06-27 2004-11-04 Armin Studer Intervertebral disk prosthesis
US20090234457A1 (en) * 2001-06-29 2009-09-17 The Regents Of The University Of California Systems, devices and methods for treatment of intervertebral disorders
US7156877B2 (en) * 2001-06-29 2007-01-02 The Regents Of The University Of California Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs
US6736815B2 (en) * 2001-09-06 2004-05-18 Core Medical, Inc. Apparatus and methods for treating spinal discs
JP2005521516A (en) 2002-04-04 2005-07-21 マシーズ メディツィナルテヒニク アクチエンゲゼルシャフトMathys Medizinaltechnik Ag Intervertebral disc prosthesis or nucleus replacement prosthesis
FR2838956B1 (en) * 2002-04-25 2005-02-04 Xavier Renard Prosthetic implant to replace a small bone
US7351256B2 (en) * 2002-05-10 2008-04-01 Cordis Corporation Frame based unidirectional flow prosthetic implant
US8388684B2 (en) 2002-05-23 2013-03-05 Pioneer Signal Technology, Inc. Artificial disc device
US7001433B2 (en) * 2002-05-23 2006-02-21 Pioneer Laboratories, Inc. Artificial intervertebral disc device
US7622562B2 (en) 2002-06-26 2009-11-24 Zimmer Orthobiologics, Inc. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
US20040054413A1 (en) * 2002-09-16 2004-03-18 Howmedica Osteonics Corp. Radiovisible hydrogel intervertebral disc nucleus
GB0221527D0 (en) * 2002-09-17 2002-10-23 Depuy Int Ltd Spinal implantation device
DE60331955D1 (en) * 2002-09-24 2010-05-12 Bogomir Gorensek Stabilizing device for intervertebral discs and methods for
US7083649B2 (en) * 2002-10-29 2006-08-01 St. Francis Medical Technologies, Inc. Artificial vertebral disk replacement implant with translating pivot point
US7273496B2 (en) * 2002-10-29 2007-09-25 St. Francis Medical Technologies, Inc. Artificial vertebral disk replacement implant with crossbar spacer and method
CA2735334A1 (en) 2002-11-05 2004-05-21 Spineology, Inc. A semi-biological intervertebral disc replacement system
US7377930B2 (en) * 2003-04-02 2008-05-27 Frank Loughran Nerve protecting tube
WO2004089240A3 (en) 2003-04-04 2007-11-01 Bharadwaj Ananthan Artificial disc prosthesis
US7419505B2 (en) * 2003-04-22 2008-09-02 Fleischmann Lewis W Collapsible, rotatable, and tiltable hydraulic spinal disc prosthesis system with selectable modular components
EP1638485B1 (en) 2003-06-20 2011-03-02 Intrinsic Therapeutics, Inc. Device for delivering an implant through an annular defect in an intervertebral disc
US20050043796A1 (en) * 2003-07-01 2005-02-24 Grant Richard L. Spinal disc nucleus implant
US7799082B2 (en) 2003-08-05 2010-09-21 Flexuspine, Inc. Artificial functional spinal unit system and method for use
US8118869B2 (en) 2006-03-08 2012-02-21 Flexuspine, Inc. Dynamic interbody device
US20060229729A1 (en) * 2003-08-05 2006-10-12 Gordon Charles R Expandable intervertebral implant for use with instrument
US7753958B2 (en) 2003-08-05 2010-07-13 Gordon Charles R Expandable intervertebral implant
US7909869B2 (en) 2003-08-05 2011-03-22 Flexuspine, Inc. Artificial spinal unit assemblies
US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
US7655012B2 (en) * 2003-10-02 2010-02-02 Zimmer Spine, Inc. Methods and apparatuses for minimally invasive replacement of intervertebral discs
WO2005037149A1 (en) * 2003-10-20 2005-04-28 Impliant Ltd. Facet prosthesis
US20050090899A1 (en) * 2003-10-24 2005-04-28 Dipoto Gene Methods and apparatuses for treating the spine through an access device
US7691146B2 (en) 2003-11-21 2010-04-06 Kyphon Sarl Method of laterally inserting an artificial vertebral disk replacement implant with curved spacer
US7217291B2 (en) 2003-12-08 2007-05-15 St. Francis Medical Technologies, Inc. System and method for replacing degenerated spinal disks
US7910124B2 (en) 2004-02-06 2011-03-22 Georgia Tech Research Corporation Load bearing biocompatible device
WO2005077013A3 (en) 2004-02-06 2009-04-09 Georgia Tech Res Inst Surface directed cellular attachment
WO2005113032A3 (en) * 2004-05-21 2006-05-04 Alastair J T Clemow Replacement of nucleus pulposus using a hydrogel
US20050277921A1 (en) * 2004-05-28 2005-12-15 Sdgi Holdings, Inc. Prosthetic joint and nucleus supplement
US20050278023A1 (en) * 2004-06-10 2005-12-15 Zwirkoski Paul A Method and apparatus for filling a cavity
US9237958B2 (en) * 2004-06-30 2016-01-19 Synergy Disc Replacement Inc. Joint prostheses
CA2703237C (en) 2007-10-25 2016-10-04 Synergy Disc Replacement, Inc. Systems and methods for vertebral disc replacement
US8172904B2 (en) * 2004-06-30 2012-05-08 Synergy Disc Replacement, Inc. Artificial spinal disc
DE602005036752T8 (en) * 2004-06-30 2013-04-25 Synergy Disc Replacement Inc. Artificial disc
KR20070056079A (en) * 2004-07-27 2007-05-31 신세스 게엠바하 Supplementation or replacement of a nucleus pulposus of an intervertebral disc
US20060089719A1 (en) * 2004-10-21 2006-04-27 Trieu Hai H In situ formation of intervertebral disc implants
US20060155379A1 (en) * 2004-10-25 2006-07-13 Heneveld Scott H Sr Expandable implant for repairing a defect in a nucleus of an intervertebral disc
KR20080012834A (en) * 2005-03-01 2008-02-12 코럼나 피티와이 리미티드 Intervertebral disc restoration
US20060247781A1 (en) * 2005-04-29 2006-11-02 Sdgi Holdings, Inc. Implant
FR2885032B1 (en) * 2005-04-29 2007-07-27 Sdgi Holdings Inc Kits and instrumentation for performing a procedure for spinal implant
US20070010889A1 (en) * 2005-07-06 2007-01-11 Sdgi Holdings, Inc. Foldable nucleus replacement device
US20070073397A1 (en) * 2005-09-15 2007-03-29 Mckinley Laurence M Disc nucleus prosthesis and its method of insertion and revision
CN103251449B (en) * 2005-10-13 2016-03-02 斯恩蒂斯有限公司 Drug packaging
US20070093906A1 (en) * 2005-10-26 2007-04-26 Zimmer Spine, Inc. Nucleus implant and method
US8197545B2 (en) 2005-10-27 2012-06-12 Depuy Spine, Inc. Nucleus augmentation delivery device and technique
US20070162127A1 (en) * 2005-12-08 2007-07-12 Sdgi Holdings, Inc. Instruments and techniques for delivering non-rigid implant members in surgical procedures
US20070150064A1 (en) * 2005-12-22 2007-06-28 Depuy Spine, Inc. Methods and devices for intervertebral augmentation
US20070150059A1 (en) * 2005-12-22 2007-06-28 Depuy Spine, Inc. Methods and devices for intervertebral augmentation using injectable formulations and enclosures
US7972337B2 (en) 2005-12-28 2011-07-05 Intrinsic Therapeutics, Inc. Devices and methods for bone anchoring
US7662183B2 (en) * 2006-01-24 2010-02-16 Timothy Haines Dynamic spinal implants incorporating cartilage bearing graft material
US20070213642A1 (en) * 2006-02-13 2007-09-13 Sdgi Holdings, Inc. Device and method for measuring parameters of intradiscal space
US7918889B2 (en) * 2006-02-27 2011-04-05 Warsaw Orthopedic, Inc. Expandable spinal prosthetic devices and associated methods
US20070233245A1 (en) * 2006-03-31 2007-10-04 Sdgi Holdings, Inc. Methods and instruments for delivering intervertebral devices
US7879027B2 (en) * 2006-04-24 2011-02-01 Warsaw Orthopedic, Inc. Controlled release devices for fusion of osteal structures
US8642060B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for osteal growth
US8642059B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for intervertebral discs
US7771414B2 (en) * 2006-04-24 2010-08-10 Warsaw Orthopedic, Inc. Controlled release devices for therapeutic treatments of spinal discs
US8133279B2 (en) * 2006-04-27 2012-03-13 Warsaw Orthopedic, Inc. Methods for treating an annulus defect of an intervertebral disc
US20070255286A1 (en) * 2006-04-27 2007-11-01 Sdgi Holdings, Inc. Devices, apparatus, and methods for improved disc augmentation
US20070255406A1 (en) * 2006-04-27 2007-11-01 Sdgi Holdings, Inc. Devices, apparatus, and methods for bilateral approach to disc augmentation
US8834496B2 (en) 2006-06-13 2014-09-16 Bret A. Ferree Soft tissue repair methods and apparatus
US9232938B2 (en) 2006-06-13 2016-01-12 Anova Corp. Method and apparatus for closing fissures in the annulus fibrosus
US8764835B2 (en) 2006-06-13 2014-07-01 Bret A. Ferree Intervertebral disc treatment methods and apparatus
US8034110B2 (en) 2006-07-31 2011-10-11 Depuy Spine, Inc. Spinal fusion implant
WO2008034135A3 (en) 2006-09-15 2008-07-24 Pioneer Surgical Tech Inc Joint arthroplasty devices having articulating members
US8715350B2 (en) 2006-09-15 2014-05-06 Pioneer Surgical Technology, Inc. Systems and methods for securing an implant in intervertebral space
US8066750B2 (en) 2006-10-06 2011-11-29 Warsaw Orthopedic, Inc Port structures for non-rigid bone plates
US8377098B2 (en) 2007-01-19 2013-02-19 Flexuspine, Inc. Artificial functional spinal unit system and method for use
US20080249529A1 (en) * 2007-03-15 2008-10-09 Depuy Spine, Inc. Dual incision disc repair device and method
US8900307B2 (en) 2007-06-26 2014-12-02 DePuy Synthes Products, LLC Highly lordosed fusion cage
US8052728B2 (en) * 2007-07-31 2011-11-08 Zimmer Spine, Inc. Method for stabilizing a facet joint
US8323341B2 (en) 2007-09-07 2012-12-04 Intrinsic Therapeutics, Inc. Impaction grafting for vertebral fusion
US20110196492A1 (en) 2007-09-07 2011-08-11 Intrinsic Therapeutics, Inc. Bone anchoring systems
US8162994B2 (en) 2007-10-22 2012-04-24 Flexuspine, Inc. Posterior stabilization system with isolated, dual dampener systems
US8267965B2 (en) 2007-10-22 2012-09-18 Flexuspine, Inc. Spinal stabilization systems with dynamic interbody devices
US8187330B2 (en) * 2007-10-22 2012-05-29 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
US8157844B2 (en) 2007-10-22 2012-04-17 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
US8523912B2 (en) 2007-10-22 2013-09-03 Flexuspine, Inc. Posterior stabilization systems with shared, dual dampener systems
US8182514B2 (en) 2007-10-22 2012-05-22 Flexuspine, Inc. Dampener system for a posterior stabilization system with a fixed length elongated member
US7846199B2 (en) * 2007-11-19 2010-12-07 Cook Incorporated Remodelable prosthetic valve
JP5441922B2 (en) 2008-01-17 2014-03-12 ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング A process for producing the same implants and related inter-inflatable vertebral
US20090222096A1 (en) * 2008-02-28 2009-09-03 Warsaw Orthopedic, Inc. Multi-compartment expandable devices and methods for intervertebral disc expansion and augmentation
KR20110003475A (en) 2008-04-05 2011-01-12 신세스 게엠바하 Expandable intervertebral implant
US20090270873A1 (en) 2008-04-24 2009-10-29 Fabian Henry F Spine surgery method and inserter
US8114156B2 (en) * 2008-05-30 2012-02-14 Edwin Burton Hatch Flexibly compliant ceramic prosthetic meniscus for the replacement of damaged cartilage in orthopedic surgical repair or reconstruction of hip, knee, ankle, shoulder, elbow, wrist and other anatomical joints
WO2010062971A9 (en) 2008-11-26 2010-10-07 Anova Corporation Methods and apparatus for anulus repair
US9526620B2 (en) 2009-03-30 2016-12-27 DePuy Synthes Products, Inc. Zero profile spinal fusion cage
US8974508B2 (en) 2009-07-06 2015-03-10 DePuy Synthes Products, LLC Expandable fixation assemblies
US9168138B2 (en) 2009-12-09 2015-10-27 DePuy Synthes Products, Inc. Aspirating implants and method of bony regeneration
US8652153B2 (en) 2010-01-11 2014-02-18 Anulex Technologies, Inc. Intervertebral disc annulus repair system and bone anchor delivery tool
ES2368984B1 (en) 2010-02-19 2012-10-08 Luis Olcina Portilla accommodative intraocular lens.
US8979860B2 (en) 2010-06-24 2015-03-17 DePuy Synthes Products. LLC Enhanced cage insertion device
JP5850930B2 (en) 2010-06-29 2016-02-03 ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング Away from the intervertebral implant
US8353964B2 (en) 2010-11-04 2013-01-15 Carpenter Clyde T Anatomic total disc replacement
US8512408B2 (en) 2010-12-17 2013-08-20 Warsaw Orthopedic, Inc. Flexiable spinal implant
US8388687B2 (en) 2011-03-25 2013-03-05 Flexuspine, Inc. Interbody device insertion systems and methods
CA2837303A1 (en) 2011-05-26 2012-11-29 Cartiva, Inc. Tapered joint implant and related tools
US9526627B2 (en) 2011-11-17 2016-12-27 Exactech, Inc. Expandable interbody device system and method
US9198769B2 (en) 2011-12-23 2015-12-01 Pioneer Surgical Technology, Inc. Bone anchor assembly, bone plate system, and method
US9381683B2 (en) 2011-12-28 2016-07-05 DePuy Synthes Products, Inc. Films and methods of manufacture
WO2014018098A1 (en) 2012-07-26 2014-01-30 DePuy Synthes Products, LLC Expandable implant
US9532881B2 (en) 2012-08-12 2017-01-03 Brian Albert Hauck Memory material implant system and methods of use
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
CN103099689B (en) * 2013-02-19 2015-08-26 哈尔滨朝阳滨辉实业发展集团有限公司 Shaped nucleus minimally invasive surgical method for preparing a prosthesis with the application and circling
US9492288B2 (en) 2013-02-20 2016-11-15 Flexuspine, Inc. Expandable fusion device for positioning between adjacent vertebral bodies
US9717601B2 (en) 2013-02-28 2017-08-01 DePuy Synthes Products, Inc. Expandable intervertebral implant, system, kit and method
US9480574B2 (en) 2013-03-14 2016-11-01 Benvenue Medical, Inc. Spinal fusion implants and devices and methods for deploying such implants
US9517144B2 (en) 2014-04-24 2016-12-13 Exactech, Inc. Limited profile intervertebral implant with incorporated fastening mechanism
US9592132B2 (en) 2015-01-09 2017-03-14 Shape Memory Orthopedics Shape-memory spinal fusion system
WO2016161025A1 (en) 2015-03-31 2016-10-06 Cartiva, Inc. Hydrogel implants with porous materials and methods
US9913727B2 (en) 2015-07-02 2018-03-13 Medos International Sarl Expandable implant

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3448737A (en) * 1966-08-16 1969-06-10 Ortho Pharma Corp Insertion unit
CA992255A (en) * 1971-01-25 1976-07-06 Cutter Laboratories Prosthesis for spinal repair
DE3743605A1 (en) * 1987-12-22 1989-07-06 Delma Elektro Med App rongeur
ES2048290T3 (en) * 1988-08-18 1994-03-16 Univ New Jersey Med Elastomeric biocompatible intervertebral disc.
US4994069A (en) * 1988-11-02 1991-02-19 Target Therapeutics Vaso-occlusion coil and method
EP0453393B1 (en) * 1990-04-20 1993-10-06 SULZER Medizinaltechnik AG Implant, particularly intervertebral prosthesis
US5176647A (en) * 1991-06-03 1993-01-05 Knoepfler Dennis J Catheter device for performing a cholangiogram during a laparoscopy surgery
US5263927A (en) * 1992-09-02 1993-11-23 Shlain Leonard M Apparatus and methods for dispensing surgical packing
US5350397A (en) * 1992-11-13 1994-09-27 Target Therapeutics, Inc. Axially detachable embolic coil assembly
EP0621020A1 (en) * 1993-04-21 1994-10-26 SULZER Medizinaltechnik AG Intervertebral prosthesis and method of implanting such a prosthesis
FR2712486A1 (en) * 1993-11-19 1995-05-24 Breslave Patrice Intervertebral prosthesis
US5571189A (en) * 1994-05-20 1996-11-05 Kuslich; Stephen D. Expandable fabric implant for stabilizing the spinal motion segment
US5522836A (en) * 1994-06-27 1996-06-04 Target Therapeutics, Inc. Electrolytically severable coil assembly with movable detachment point
DE69522060D1 (en) * 1994-09-08 2001-09-13 Stryker Technologies Corp Spinal disc nucleus of hydrogel
US5562736A (en) * 1994-10-17 1996-10-08 Raymedica, Inc. Method for surgical implantation of a prosthetic spinal disc nucleus
US5716416A (en) * 1996-09-10 1998-02-10 Lin; Chih-I Artificial intervertebral disk and method for implanting the same

Cited By (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080314593A1 (en) * 2001-04-24 2008-12-25 Shell Oil Company In situ thermal processing of an oil shale formation using a pattern of heat sources
US7267687B2 (en) 2001-10-02 2007-09-11 Rex Medical, L.P Spinal implant and method of use
US9095449B2 (en) 2001-10-02 2015-08-04 Rex Medical, L. P. Method of inserting a spinal implant
US20060129242A1 (en) * 2001-12-28 2006-06-15 Brian Bergeron Pseudo arthrosis device
US7112223B2 (en) 2001-12-28 2006-09-26 Abbott Spine Inc. Pseudo arthrosis device
US20030229397A1 (en) * 2001-12-28 2003-12-11 Davis Reginald J. Pseudo arthrosis device
US20080015698A1 (en) * 2002-10-31 2008-01-17 Marino James F Spinal disc implant
US9814589B2 (en) 2003-02-14 2017-11-14 DePuy Synthes Products, Inc. In-situ formed intervertebral fusion device and method
US9925060B2 (en) 2003-02-14 2018-03-27 DePuy Synthes Products, Inc. In-situ formed intervertebral fusion device and method
US9808351B2 (en) 2003-02-14 2017-11-07 DePuy Synthes Products, Inc. In-situ formed intervertebral fusion device and method
US9814590B2 (en) 2003-02-14 2017-11-14 DePuy Synthes Products, Inc. In-situ formed intervertebral fusion device and method
US9801729B2 (en) 2003-02-14 2017-10-31 DePuy Synthes Products, Inc. In-situ formed intervertebral fusion device and method
US9788963B2 (en) 2003-02-14 2017-10-17 DePuy Synthes Products, Inc. In-situ formed intervertebral fusion device and method
US20060136064A1 (en) * 2003-06-02 2006-06-22 Sherman Michael C Intervertebral disc implants and methods for manufacturing and using the same
US7901460B2 (en) * 2003-06-02 2011-03-08 Warsaw Orthopedic, Inc. Intervertebral disc implants and methods for manufacturing and using the same
US8337561B2 (en) 2003-07-15 2012-12-25 Spinal Generations, Llc Spinal disc prosthesis system
US20100168863A1 (en) * 2003-07-15 2010-07-01 Spinal Generations, Llc Spinal disc prosthesis system
US20050015152A1 (en) * 2003-07-15 2005-01-20 Spinal Generations Spinal disc prosthesis system
US7695515B2 (en) 2003-07-15 2010-04-13 Spinal Generations, Llc Spinal disc prosthesis system
US8097038B2 (en) 2003-09-30 2012-01-17 Mmsn Limited Partnership Prosthetic vertebral assembly
US7255714B2 (en) 2003-09-30 2007-08-14 Michel H. Malek Vertically adjustable intervertebral disc prosthesis
US20070185577A1 (en) * 2003-09-30 2007-08-09 Malek Michel H Intervertebral disc prosthesis
US20050071007A1 (en) * 2003-09-30 2005-03-31 Malek Michel H. Intervertebral disc prosthesis
US7402176B2 (en) 2003-09-30 2008-07-22 Malek Michel H Intervertebral disc prosthesis
US8486113B2 (en) 2003-11-25 2013-07-16 Michel H. Malek Spinal stabilization systems
US8080061B2 (en) * 2005-06-20 2011-12-20 Synthes Usa, Llc Apparatus and methods for treating bone
US20070055274A1 (en) * 2005-06-20 2007-03-08 Andreas Appenzeller Apparatus and methods for treating bone
US7785368B2 (en) 2005-08-16 2010-08-31 Benvenue Medical, Inc. Spinal tissue distraction devices
US20100174321A1 (en) * 2005-08-16 2010-07-08 Laurent Schaller Methods of Distracting Tissue Layers of the Human Spine
US9788974B2 (en) 2005-08-16 2017-10-17 Benvenue Medical, Inc. Spinal tissue distraction devices
US7955391B2 (en) 2005-08-16 2011-06-07 Benvenue Medical, Inc. Methods for limiting the movement of material introduced between layers of spinal tissue
US7963993B2 (en) 2005-08-16 2011-06-21 Benvenue Medical, Inc. Methods of distracting tissue layers of the human spine
US7967865B2 (en) 2005-08-16 2011-06-28 Benvenue Medical, Inc. Devices for limiting the movement of material introduced between layers of spinal tissue
US7967864B2 (en) 2005-08-16 2011-06-28 Benvenue Medical, Inc. Spinal tissue distraction devices
US7670374B2 (en) 2005-08-16 2010-03-02 Benvenue Medical, Inc. Methods of distracting tissue layers of the human spine
US9492291B2 (en) * 2005-08-16 2016-11-15 Kunovus Pty Ltd. Systems, methods and apparatuses for formation and insertion of tissue prosthesis
US7670375B2 (en) 2005-08-16 2010-03-02 Benvenue Medical, Inc. Methods for limiting the movement of material introduced between layers of spinal tissue
US7666227B2 (en) 2005-08-16 2010-02-23 Benvenue Medical, Inc. Devices for limiting the movement of material introduced between layers of spinal tissue
US7666226B2 (en) 2005-08-16 2010-02-23 Benvenue Medical, Inc. Spinal tissue distraction devices
US9326866B2 (en) 2005-08-16 2016-05-03 Benvenue Medical, Inc. Devices for treating the spine
US20090177207A1 (en) * 2005-08-16 2009-07-09 Laurent Schaller Method of interdigitating flowable material with bone tissue
US9066808B2 (en) 2005-08-16 2015-06-30 Benvenue Medical, Inc. Method of interdigitating flowable material with bone tissue
US9044338B2 (en) 2005-08-16 2015-06-02 Benvenue Medical, Inc. Spinal tissue distraction devices
US8979929B2 (en) 2005-08-16 2015-03-17 Benvenue Medical, Inc. Spinal tissue distraction devices
US8801787B2 (en) 2005-08-16 2014-08-12 Benvenue Medical, Inc. Methods of distracting tissue layers of the human spine
US8961609B2 (en) 2005-08-16 2015-02-24 Benvenue Medical, Inc. Devices for distracting tissue layers of the human spine
US8366773B2 (en) 2005-08-16 2013-02-05 Benvenue Medical, Inc. Apparatus and method for treating bone
US8454617B2 (en) 2005-08-16 2013-06-04 Benvenue Medical, Inc. Devices for treating the spine
US8057544B2 (en) 2005-08-16 2011-11-15 Benvenue Medical, Inc. Methods of distracting tissue layers of the human spine
US8882836B2 (en) 2005-08-16 2014-11-11 Benvenue Medical, Inc. Apparatus and method for treating bone
US8556978B2 (en) 2005-08-16 2013-10-15 Benvenue Medical, Inc. Devices and methods for treating the vertebral body
US8591583B2 (en) 2005-08-16 2013-11-26 Benvenue Medical, Inc. Devices for treating the spine
US20140257417A1 (en) * 2005-08-16 2014-09-11 Spinecell Private Limited Systems, methods and apparatuses for formation and insertion of tissue prosthesis
US8808376B2 (en) 2005-08-16 2014-08-19 Benvenue Medical, Inc. Intravertebral implants
US20100174375A1 (en) * 2005-08-16 2010-07-08 Laurent Schaller Spinal Tissue Distraction Devices
US9259326B2 (en) 2005-08-16 2016-02-16 Benvenue Medical, Inc. Spinal tissue distraction devices
US9289240B2 (en) 2005-12-23 2016-03-22 DePuy Synthes Products, Inc. Flexible elongated chain implant and method of supporting body tissue with same
US20080009943A1 (en) * 2006-06-29 2008-01-10 Depuy Spine, Inc. Insert for nucleus implant
US7740659B2 (en) * 2006-06-29 2010-06-22 Depuy Spine, Inc. Insert for nucleus implant
US20110166602A1 (en) * 2006-07-28 2011-07-07 Malek Michel H Bone anchor device
US8142507B2 (en) 2006-11-16 2012-03-27 Rex Medical, L.P. Spinal implant and method of use
US20080133012A1 (en) * 2006-11-16 2008-06-05 Mcguckin James F Spinal implant and method of use
US8287599B2 (en) 2006-11-16 2012-10-16 Rex Medical, L.P. Spinal implant and method of use
US8920506B2 (en) * 2006-11-16 2014-12-30 Rex Medical, L.P. Spinal implant and method of use
US20130030533A1 (en) * 2006-11-16 2013-01-31 Rex Medical Spinal implant and method of use
US9259324B2 (en) 2006-11-16 2016-02-16 Rex Medical, L.P. Spinal implant and method of use
US20110208308A1 (en) * 2006-11-28 2011-08-25 Columna Pty Ltd Tissue prosthesis insertion system and method
US9662227B2 (en) * 2006-11-28 2017-05-30 Kunovus Party Ltd Tissue prosthesis insertion system and method
US8728161B2 (en) * 2006-11-28 2014-05-20 Spinecell Private Ltd Tissue prosthesis insertion system and method
US20140249634A1 (en) * 2006-11-28 2014-09-04 Spinecell Party, Ltd Tissue prosthesis insertion system and method
US9192485B2 (en) * 2006-11-28 2015-11-24 Spincell Private Ltd Tissue prosthesis insertion system and method
US20160074177A1 (en) * 2006-11-28 2016-03-17 Kunovus Pty. Ltd (formerly Spinecell Pty. Ltd) Tissue prosthesis insertion system and method
US9433512B2 (en) * 2006-11-28 2016-09-06 Kunovns Party Ltd. Tissue prosthesis insertion system and method
US7905922B2 (en) 2006-12-20 2011-03-15 Zimmer Spine, Inc. Surgical implant suitable for replacement of an intervertebral disc
US9642712B2 (en) 2007-02-21 2017-05-09 Benvenue Medical, Inc. Methods for treating the spine
US8968408B2 (en) 2007-02-21 2015-03-03 Benvenue Medical, Inc. Devices for treating the spine
US8696753B2 (en) * 2007-07-07 2014-04-15 Jmea Corporation Disk fusion implant
US20120221107A1 (en) * 2007-07-07 2012-08-30 Jmea Corporation Disk Fusion Implant
US8617214B2 (en) 2008-01-07 2013-12-31 Mmsn Limited Partnership Spinal tension band
US7935133B2 (en) 2008-02-08 2011-05-03 Mmsn Limited Partnership Interlaminar hook
US8652209B2 (en) * 2008-04-04 2014-02-18 Clariance Nuclear implant
US20120277862A1 (en) * 2008-04-04 2012-11-01 Clariance Nuclear implant
US20100121378A1 (en) * 2008-11-10 2010-05-13 Malek Michel H Facet fusion system
US8187304B2 (en) 2008-11-10 2012-05-29 Malek Michel H Facet fusion system
US9492214B2 (en) 2008-12-18 2016-11-15 Michel H. Malek Flexible spinal stabilization system
US8535327B2 (en) 2009-03-17 2013-09-17 Benvenue Medical, Inc. Delivery apparatus for use with implantable medical devices
US9301787B2 (en) 2010-09-27 2016-04-05 Mmsn Limited Partnership Medical apparatus and method for spinal surgery
US9314252B2 (en) 2011-06-24 2016-04-19 Benvenue Medical, Inc. Devices and methods for treating bone tissue
US8814873B2 (en) 2011-06-24 2014-08-26 Benvenue Medical, Inc. Devices and methods for treating bone tissue
US9585761B2 (en) 2013-03-14 2017-03-07 DePuy Synthes Products, Inc. Angulated rings and bonded foils for use with balloons for fusion and dynamic stabilization
US20140277464A1 (en) * 2013-03-14 2014-09-18 Synthes Usa, Llc Expandable coil spinal implant
US20160250032A1 (en) * 2013-03-14 2016-09-01 DePuy Synthes Products, Inc. Expandable coil spinal implant
US9358120B2 (en) * 2013-03-14 2016-06-07 DePuy Synthes Products, Inc. Expandable coil spinal implant
US9889015B2 (en) * 2013-03-14 2018-02-13 DePuy Synthes Products, Inc. Expandable coil spinal implant
US9572676B2 (en) 2013-03-14 2017-02-21 DePuy Synthes Products, Inc. Adjustable multi-volume balloon for spinal interventions
US9901457B2 (en) 2014-10-16 2018-02-27 Jmea Corporation Coiling implantable prostheses

Also Published As

Publication number Publication date Type
US5919235A (en) 1999-07-06 grant
US6165218A (en) 2000-12-26 grant
EP1350490B1 (en) 2006-12-27 grant
JP3944753B2 (en) 2007-07-18 grant
DE59510855D1 (en) 2004-03-18 grant
EP1350490A2 (en) 2003-10-08 application
EP0773008B1 (en) 2004-02-11 grant
DE59511075D1 (en) 2007-02-08 grant
ES2278091T3 (en) 2007-08-01 grant
EP1350490A3 (en) 2004-01-21 application
EP0773008A1 (en) 1997-05-14 application
US6660037B1 (en) 2003-12-09 grant
JPH09164156A (en) 1997-06-24 application
ES2211895T5 (en) 2009-10-29 grant
US6610094B2 (en) 2003-08-26 grant
ES2211895T3 (en) 2004-07-16 grant
EP0773008B2 (en) 2009-05-20 grant

Similar Documents

Publication Publication Date Title
US6245108B1 (en) Spinal fusion implant
US8267986B2 (en) Vascular stenting for aneurysms
US6168625B1 (en) Adjustable length prosthesis useful for ossicular replacement and reconstruction
US5800526A (en) Multi-anchor stent
US6019793A (en) Surgical prosthetic device
US6299642B1 (en) Bone cement plug for deployment in a bone canal
US6887267B2 (en) Insertion catheter for vascular prosthesis
US6120506A (en) Lordotic spinal implant
US5649945A (en) Spinal anulus cutter
US6312421B1 (en) Aneurysm embolization material and device
US4186486A (en) Dental prosthesis
US7621956B2 (en) Prosthetic spinal disc replacement
US4718916A (en) Femur head prosthesis
US7740659B2 (en) Insert for nucleus implant
US8236058B2 (en) Spine surgery method and implant
US4641648A (en) Surgical instrument
US5913896A (en) Interwoven dual sinusoidal helix stent
US20060217747A1 (en) Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US7052516B2 (en) Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US20050216087A1 (en) Disk repair structures for positioning disk repair material
US20040059417A1 (en) Apparatus and method for the in-situ formation of a structural prosthesis
US20030176921A1 (en) Two-part prosthetic nucleus replacement for surgical reconstruction of intervertebral discs
US20110035011A1 (en) Expandable intervertebral implant
US20070027471A1 (en) Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US20080300667A1 (en) System for delivering a stent

Legal Events

Date Code Title Description
AS Assignment

Owner name: UBS AG, STAMFORD BRANCH AS SECURITY AGENT FOR THE

Free format text: SECURITY INTEREST;ASSIGNORS:CENTERPULSE ORTHOPEDICS INC.;CENTERPULSE USA HOLDING CO., CORPORATION, DELAWARE;CENTERPULSE USA INC., CORPORATION, DELAWARE;AND OTHERS;REEL/FRAME:013467/0328

Effective date: 20021029

AS Assignment

Owner name: CENTERPULSE USA INC., TEXAS

Free format text: PATENT RELEASE AGREEMENT;ASSIGNOR:UBS AG, STAMFORD BRANCH;REEL/FRAME:014699/0404

Effective date: 20031002

AS Assignment

Owner name: CENTERPULSE ORTHOPEDICS LTD., SWITZERLAND

Free format text: CHANGE OF NAME;ASSIGNOR:SULZER ORTHOPEDICS LTD.;REEL/FRAME:015400/0554

Effective date: 20030408

AS Assignment

Owner name: ZIMMER GMBH, SWITZERLAND

Free format text: NOTIFICATION OF TRANSFORMATION AND ACQUISITION OF ASSETS;ASSIGNOR:CENTERPULSE ORTHOPAEDIE AG;REEL/FRAME:016735/0035

Effective date: 20040628

AS Assignment

Owner name: ZIMMER GMBH, SWITZERLAND

Free format text: TRANSFORMATION WITHOUT LIQUIDATION;ASSIGNOR:CENTERPULSE ORTHOPEDICS LTD;REEL/FRAME:017897/0708

Effective date: 20040630

Owner name: ZIMMER GMBH,SWITZERLAND

Free format text: TRANSFORMATION WITHOUT LIQUIDATION;ASSIGNOR:CENTERPULSE ORTHOPEDICS LTD;REEL/FRAME:017897/0708

Effective date: 20040630

FPAY Fee payment

Year of fee payment: 4

FPAY Fee payment

Year of fee payment: 8

REMI Maintenance fee reminder mailed
LAPS Lapse for failure to pay maintenance fees
FP Expired due to failure to pay maintenance fee

Effective date: 20150826