US20020013605A1 - Surgical helical fastener with applicator - Google Patents

Surgical helical fastener with applicator Download PDF

Info

Publication number
US20020013605A1
US20020013605A1 US09968100 US96810001A US2002013605A1 US 20020013605 A1 US20020013605 A1 US 20020013605A1 US 09968100 US09968100 US 09968100 US 96810001 A US96810001 A US 96810001A US 2002013605 A1 US2002013605 A1 US 2002013605A1
Authority
US
Grant status
Application
Patent type
Prior art keywords
fastener
helical coil
applicator
tissue
end
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
US09968100
Other versions
US6562051B1 (en )
Inventor
Lee Bolduc
Thomas Kramer
Brian Hodges
Tim McCoy
John Lunsford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covidien LP
Original Assignee
Covidien AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064Surgical staples, i.e. penetrating the tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/068Surgical staplers, e.g. containing multiple staples or clamps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0469Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/128Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips
    • A61B17/1285Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for applying or removing clamps or clips for minimally invasive surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00004(bio)absorbable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06066Needles, e.g. needle tip configurations
    • A61B2017/06076Needles, e.g. needle tip configurations helically or spirally coiled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166Sutures
    • A61B2017/06171Sutures helically or spirally coiled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/064Surgical staples, i.e. penetrating the tissue
    • A61B2017/0649Coils or spirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0063Implantable repair or support meshes, e.g. hernia meshes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S227/00Elongated-member-driving apparatus
    • Y10S227/901Surgical clip appliers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S227/00Elongated-member-driving apparatus
    • Y10S227/902Surgical clips or staples
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S606/00Surgery
    • Y10S606/907Composed of particular material or coated
    • Y10S606/91Polymer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S606/00Surgery
    • Y10S606/916Tool for installing or removing orthopedic fastener

Abstract

A helical fastener having a high retentive surface area is provided and has a first end for enhancing penetration into tissue and a second end comprising a coil sectioning a diameter of the fastener for receiving longitudinal and rotational forces. The helical fasteners are attached to body tissue by a fastener applicator having a proximal portion comprising a handle and an actuator and an elongate distal portion for housing a plurality of fasteners. A transferring action of the actuator provides longitudinal and rotational movement of the fasteners out of the distal portion and into body tissue.

Description

    BACKGROUND OF THE INVENTION
  • This invention relates to surgical fasteners and their associated applicators, and more particularly, surgically fastening material to tissue. [0001]
  • Fasteners have been used surgically to eliminate the need for suturing, which is both time consuming and inconvenient. In many applications the surgeon can use a stapler apparatus, i.e., a fastener implanting device loaded with surgical fasteners to accomplish in a few seconds what would have taken many minutes to perform by suturing. This reduces blood loss and trauma to the patient. [0002]
  • Conventional surgical fasteners have been in the form of ordinary metal staples, which are bent by the delivery apparatus to hook together body tissue. Typically, conventional staples comprise a pair of legs joined together at one end by a crown. The crown may be a straight member connecting the legs or may form an apex. Moreover, the legs may extend substantially perpendicular from the crown or at some angle therefrom. Irrespective of the particular configuration, however, conventional staples are designed so that they may be deformed to hold body tissue. [0003]
  • Accordingly, the stapler applicators have conventionally embodied structure functioning to project the conventional staple into tissue as well as to deform the staple so that it is retained against the tissue. Generally speaking, typical applicators include an anvil cooperating with means to eject the conventional staple from the applicator. In some applications, access to the body tissue from two opposite directions is available and the anvil can operate to deform the legs of the staple after they have passed through the body tissue. In applications where access to the tissue is from only one direction, the anvil may deform the crown of the conventional staple so that its legs will project into the body tissue in a fashion so as to hold the staple against the tissue. [0004]
  • Since conventional staples require deformation and must cooperate with applicators having an anvil or other means to deform the staples, conventional applicators typically comprise complex structures and can be prohibitively expensive. Conventional applicators must embody structure functioning to not only eject the fasteners but to do so in a manner so that the fastener deforms properly and timely. [0005]
  • In some applications, conventional applicators must be equipped with structure functioning to move the anvil into and out of position so that when the fastener is ejected from the applicator, the anvil is properly positioned and once fastener deformation is complete, moves out of position, thereby allowing the process to be repeated. Moreover, the anvil must be formed into a proper configuration so that fastener deformation can be repeated accurately. Further, the force between the fastener and the anvil must be controlled so that repeated deformation is accomplished. The objectives of many inventions in this field have been to accomplish these goals by the simple manipulation of a single lever. It is to be appreciated, therefore, that the fastener applicators have become complex and expensive instruments. [0006]
  • Two part fasteners have also been conventionally utilized, where a barbed staple is used in conjunction with a retaining piece to hold the staple in place. Typically, the two part staple comprises a crown or backspan and two barbed prongs which are engaged and locked into a separate retainer piece. In use, the staple is pressed into the body tissue so that the barbs penetrate the tissue and emerge from the other side where they are then locked into the retainer piece. Retainers prevent the staple from working loose from the tissue. The two piece fasteners cannot be unlocked and are not removable. [0007]
  • Like other conventional applications, however, the two piece fasteners require the staple delivery apparatus to have access to both sides of the tissue. Thus, as with the other conventional applications, two piece fasteners are limited since they cannot be used where access to tissue is from one direction only. [0008]
  • In those situations where access to body tissues is limited to one direction, as in grafting procedures, deformable surgical fasteners have been conventionally employed. As mentioned previously, however, the applicators commonly used in these situations embody an anvil cooperating with a fastener to deform it and consequently, tend to be of a complex design. [0009]
  • Some advancements have been made in this area so that applicators functioning to attach grafts to tissue, for instance, are not required to embody an anvil and may, therefore, have a more simple design. In particular, it has been suggested in the art to employ fasteners with barbs, thereby eliminating the need for deforming the fastener. These fasteners are limited, however, since the path created in the graft and tissue by the barbs as the fastener is pressed into the graft and tissue may allow the fastener to loosen its grip or to entirely back out of engagement. Moreover, due to their sole reliance upon barbs to retain tissue, the barb fasteners are further limited in that they may not have a great enough retentive surface area for securely holding tissue in place. [0010]
  • To circumvent or overcome the problems and limitations associated with conventional fasteners and applicators, a simple applicator that dispenses a surgical fastener having high surface area for retentive contact with tissue and that can be delivered into body tissue from one direction may be employed. The present invention embodies these characteristics. [0011]
  • SUMMARY OF THE INVENTION
  • The invention includes a surgical fastener and an applicator used in delivering the fastener into body tissue. The fastener and applicator of the present invention may be used in a number of medical procedures including ligating tissue, hernia mesh repair, bladder neck suspension, and in conjunction with implant drug delivery systems or procedures involving positioning of surgical or implantable devices in a patient's body. [0012]
  • The preferred embodiment of the surgical fastener of the present invention is formed into the configuration of a continuous helical coil. The continuous helical coil is longitudinally collapsible and expandable. At the distal end of the helical fastener is a point for enhancing penetration into tissue. The proximal end of the helical fastener has a T-bar which sections the diameter of the fastener, thereby providing a surface for receiving and transmitting longitudinal and rotational forces so that the fastener may be driven into tissue by a corkscrew action. The pitch and length of the helical fastener may vary upon the application as can its diameter and configuration of the most proximal and distal coils comprising the fastener. Additionally, the material selection and fastener stiffness may be selected with a particular application in mind. [0013]
  • In another embodiment of the surgical fastener, the fastener comprises a double continuous helical coil that is also longitudinally collapsible and expandable and may embody various configurations depending upon the application. Moreover, the distal end of the double helical fastener comprises two points for enhancing penetration into tissue and its proximal end comprises a connector bar which connects the two helixes as well as sections the diameter of the double helical fastener. In yet another embodiment, the surgical fastener further comprises a pivot post extending through the center of the fastener and operating to provide the fastener with a stable pivot. In any of the embodiments, one or more barbs may be employed near the point to enhance anchoring characteristics. [0014]
  • A preferred embodiment of the fastener applicator of the present invention includes a proximal portion and a distal portion. The proximal portion is preferably fabricated to be a “reusable” component and the distal portion a “disposable” component. Alternatively, both the distal and proximal portion can be made disposable. The distal portion is elongate and embodies an outer tube housing an inner rotator, a lock clip/indicator and a load spring. The proximal portion includes a handle. In the preferred embodiment of the distal portion, a thread form comprising an interlock spring is provided within the outer tube. The rotator includes a structure running longitudinally along its length that functions to receive the T-bar or connector bar of the fastener and in this way, the rotator may hold a plurality of fasteners. The load spring applies a force against the lock clip/indicator operating to bias the plurality of springs distally within the outer tube and towards the nose piece. The thread form functions to engage the coils of the helical fasteners and when rotating the rotator, a fastener is driven from the distal end of the applicator. In other embodiments of the applicator, the distal end has various other structures functioning to engage the coils of the fastener and to drive them from the distal end of the applicator. In one other embodiment, the distal end comprises a nose piece protrusion for engaging the fastener. [0015]
  • In order to cause the rotator to rotate, the proximal portion of the applicator has a handle and an actuator cooperating with the rotator. In a preferred embodiment, the proximal portion of the applicator embodies a lever pivotally attached about a midpoint to the handle. A first end of the lever is configured to be gripped by hand and a second end is adapted to engage a nut driver. The nut driver travels along a helical lead screw which is connected to the rotator. When the lever is squeezed by hand the nut driver travels along the lead screw causing it to rotate, and through the connection of the lead screw to the rotator, the action of the lead screw causes the rotator to rotate. [0016]
  • Further, the lever comprises a midsection extension. Pivotally attached to the midsection extension of the lever is a spring loaded pawl adapted to releasably engage gear teeth formed in the interior of the handle. The spring loaded pawl prohibits the lever from backstroking until it has been completely depressed. Upon complete depression of the lever, the pawl clears the gear teeth and the spring, biasing the pawl, rotates the pawl away from the teeth, thereby allowing the lever to return to its undepressed condition. [0017]
  • In another embodiment of the proximal portion of the applicator, the lever is pivotally attached at a first end to the handle, the second end being adapted to engage the nut driver. Further, rather than embodying a spring loaded pawl, this alternate embodiment of the proximal portion includes a clutch assembly or releasable connection between the lead screw and rotator and cooperating means to prohibit the lever from backstroking until it has been completely depressed. [0018]
  • Other features and advantages of the present invention will become apparent from the following detailed description, taken in conjunction with the accompanying drawings, which illustrate, by way of example, the principals of the invention. [0019]
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • FIG. 1 depicts a perspective view of a fastener of the present invention, illustrating a side view of a helical fastener. [0020]
  • FIG. 1A depicts another perspective view of the fastener of the present invention, illustrating an end view of the helical fastener. [0021]
  • FIG. 1B depicts a schematic view of a fastener of the present invention, illustrating a substantially collapsed helical fastener with a relatively small gap that has been partially inserted into tissue. [0022]
  • FIG. 1C depicts a schematic view of a fastener of the present invention, illustrating the helical fastener depicted in FIG. 1B completely inserted into tissue. [0023]
  • FIG. 1D depicts a schematic view of a fastener of the present invention, illustrating a substantially collapsed helical fastener with a relatively large gap that has been partially inserted into the tissue. [0024]
  • FIG. 1E depicts a schematic view of a fastener of the present invention, illustrating the helical fastener depicted in FIG. 1D completely inserted into tissue. [0025]
  • FIG. 1F depicts a perspective view of another embodiment of the present invention, illustrating an end view of the helical fastener. [0026]
  • FIG. 2 depicts a perspective view of another embodiment of the present invention, illustrating a double helical fastener. [0027]
  • FIG. 2A is a front view of the double helical fastener of FIG. 2. [0028]
  • FIG. 2B is side view of the double helical fastener of FIG. 2. [0029]
  • FIG. 2C is a top view of the double helical fastener of FIG. 2. [0030]
  • FIG. 3 is a perspective view of yet another embodiment of the present invention, illustrating another design of a double helical fastener. [0031]
  • FIG. 3A is a front view of the double helical fastener of FIG. 3. [0032]
  • FIG. 3B is a side view of the double helical fastener of FIG. 3. [0033]
  • FIG. 3C is a top view of the double helical fastener of FIG. 3. [0034]
  • FIG. 4 is a perspective view of the present invention, illustrating a helical fastener with a central post. [0035]
  • FIG. 5 depicts a schematic cross-sectional view of an applicator of the present invention, illustrating a side view of the applicator. [0036]
  • FIG. 6 is a schematic cross-sectional side view of a terminal end of the applicator. [0037]
  • FIG. 6A is a schematic cross-sectional end view of a terminal end of the applicator. [0038]
  • FIG. 7 is a schematic cross-sectional view of the terminal end of the applicator, illustrating the preferred embodiment of the terminal end. [0039]
  • FIG. 7A is a schematic cross-sectional end view of the preferred embodiment of the terminal end of the application shown in FIG. 7. [0040]
  • FIG. 8 is a schematic cross-sectional view of the terminal end of the applicator, illustrating another embodiment of the terminal end. [0041]
  • FIG. 8A is a schematic cross-sectional end view of the embodiment of the terminal end of the applicator shown in FIG. 8. [0042]
  • FIG. 9 is a schematic cross-sectional view of the terminal end of the applicator, illustrating yet another embodiment of the terminal end. [0043]
  • FIG. 9A is a schematic cross-sectional end view of the embodiment of the terminal end of the applicator shown in FIG. 9. [0044]
  • FIG. 10 is a schematic cross-sectional view of the terminal end of the applicator, illustrating still yet another embodiment of the terminal end. [0045]
  • FIG. 10A is a schematic cross-sectional end view of the embodiment of the terminal end of the applicator shown in FIG. 10. [0046]
  • FIG. 11 is a schematic cross-sectional view of the terminal end of the applicator, illustrating another embodiment of the terminal end. [0047]
  • FIG. 11A is a schematic cross-sectional end view of the embodiment of the terminal end of the applicator shown in FIG. 11. [0048]
  • FIG. 12 is a schematic cross-sectional view of the terminal end of the applicator, illustrating a further embodiment of the terminal end. [0049]
  • FIG. 12A is a schematic cross-sectional end view of the embodiment of the terminal end of the applicator shown in FIG. 12. [0050]
  • FIG. 13 is a schematic cross-sectional view of the terminal end of the applicator, illustrating a still further embodiment of the terminal end. [0051]
  • FIG. 14 is a schematic cross-sectional view of the terminal end of the applicator, illustrating still yet another embodiment of the terminal end. [0052]
  • FIG. 15 is a schematic cross-sectional view of another applicator of the present invention, illustrating a side view of the applicator. [0053]
  • FIG. 16 is a schematic partial crosssectional view of a releasable connection between the lead screw and rotator. [0054]
  • FIG. 16A is schematic representation of a distal end of the lead screw, illustrating an end view of the lead screw. [0055]
  • FIG. 16B is a schematic representation of the distal end of the lead screw, illustrating a side view of the lead screw depicted in FIG. 16. [0056]
  • FIG. 16C is a schematic representation of the proximal end of the rotator, illustrating a side view of the rotator. [0057]
  • FIG. 16D is a schematic representation of the proximal end of the rotator, illustrating an end view of the rotator depicted in FIG. 16B. [0058]
  • DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
  • As is shown in the drawings, which are included for purposes of illustration and not by way of limitation, the invention is embodied in a continuous helical fastener and an applicator therefore The helical fastener has a high retentive surface area and the applicator has a simple design and functions to dispense the helical fasteners, without substantially deforming the fasteners, into body tissue, access to which is from one direction only. Some conventional fasteners require deformation to hold tissue and are consequently limited since they require complex applicators to attach them into tissue. Other conventional fasteners lack high retentive surface area for securely holding tissue. Still other fastener/applicator systems require access to tissue from two directions in order to accomplish attaching a fastener to tissue. Thus, the helical fastener and applicator of the present invention provides a superior means to attach fasteners to tissue. [0059]
  • One embodiment of the present invention (FIGS. 1, 1A and [0060] 5) is embodied in a helical fastener 10 which is attached to tissue by employing a novel applicator 12 which rotates the fastener 10 into tissue. The dimensions and physical characteristics of the helical fastener 10 are selected to insure a secure attachment of the fastener 10 to tissue. Similarly, the dimensions and physical characteristics of the applicator 12 utilized to dispense the fasteners 10 into tissue are dependent upon the application.
  • In a preferred embodiment, the fastener [0061] 10 is formed into the configuration of a continuous helix and may have a depth 16, a diameter 18 and a pitch 20 determined by the application. The continuous helix may be longitudinally collapsible and expandable. The cross-sectional profile of the continuous helix is substantially circular in the preferred embodiment but can be square, rectangular or triangular. In a particular application such as mesh anchoring for hernia repair, the pre-formed pitch can be 0.050 inches. However, the pre-formed pitch can vary from 0 to a maximum of approximately 3.0 times the coil diameter. In other embodiments, it is contemplated that the pitch 20 vary along the length of the fastener 10 so as to optimize the retaining force of the fastener 10. Moreover, since the continuous helical coil is preferably longitudinally collapsible-and expandable, upon insertion into tissue, the final pitch 31 may be less than or greater than the pre-formed pitch. If the coil is made of rigid construction, as is also contemplated, pitch would be made substantially fixed. The diameter in the preferred embodiment may be 5 mm; however, designs ranging from 1 mm and up are contemplated. In practice, the depth 16 of the fastener 10 must be selected so that the extent of fastener penetration into tissue is sufficient to hold the fastener 10 in place.
  • Moreover, distal end [0062] 22 of the fastener 10 is to be configured such that a gap 23 exists between the most distal coil 27 (or first coil) of the fastener 10 and its adjacent coil. As may be appreciated from the preferred embodiment of FIGS. 1B through 1E, as the fastener 10 is pressed against tissue 25, all of the coils substantially collapse except the most distal coil 27, leaving the gap 23 to determine the path the fastener 10 takes as it is rotated into the tissue 25 and more importantly, the extent of penetration 29 into the tissue 25 and final pitch 31 of the fastener 10 in tissue. Although FIG. 1B shows substantially all of the coils being collapsed, it is to be appreciated that, depending upon the applicator utilized to implant the fastener 10, fewer coils than all of the coils may be collapsed at any one time. It remains, however, that since the fastener 10 is longitudinally collapsible and expandable, it is the gap 23 that generally determines final pitch 31. Accordingly, the magnitude of the gap 23 can be varied, depending upon the application, to achieve the desired final pitch 31 and penetration 29 in tissue. Thus, the greater the gap 23, upon insertion of the fastener 10 in tissue, the greater the penetration 29 and final pitch 31 of the fastener 10 in tissue.
  • In the preferred embodiment, the distal end [0063] 22 of the helical fastener 10 terminates with a point 24. The point 24 may be sharp or blunt depending upon the tissue to which the fastener 10 will be affixed. Additionally, one or more barbs or a sharp point projecting in reverse direction to point 24 (not shown) can be added to fastener 10 near point 24 to enhance anchoring characteristics of the fastener. A proximal end 26 of the helical fastener 10 may comprise structure functioning to receive and transmit applied longitudinal forces. In the preferred embodiment, the most proximal coil is formed into a T-bar 33 that perpendicularly sections the diameter 18 of the fastener 10. In alternate embodiments, it is also contemplated that the most proximal coil section the diameter 18 non-perpendicularly or be formed into a spiral 35 existing in a single plane (See FIG. 1F).
  • Concerning the material of the helical fastener [0064] 10, it is contemplated in the preferred embodiment that the fastener be made from semi-stiff implantable wire, such as titanium, wound into a helical shape. In alternate embodiments, the helical fastener 10 may comprise plastic or absorbable materials. Examples of materials that can be used in constructing the helical fastener 10 include titanium, titanium alloys, stainless steel, nickel, chrome alloys and any other biocompatible implantable metals. Other options for materials are liquid crystal polymers, HDPE, polyglycolic acid, and polyglycolid hydroxgacetic acid. Further, it may also be desirable to coat the fastener, or a portion thereof, with a biocompatible lubricious material that provides for easier delivery of the fastener into tissue.
  • In another embodiment of the surgical fastener, the fastener [0065] 110 is formed into the configuration of a double helix (See FIGS. 2-2C). By embodying a double helix, the fastener 110 has increased retentive strength as well as means to balance the fastener 110 as it is pressed into tissue. As with the helical fastener 10, the configuration of the double helical fastener 110, i.e., the pre-formed pitch and diameter, may be varied for a particular application and a barb may be employed to enhance anchoring in tissue. Moreover, the materials contemplated are the same as those for the helical fasteners. Further, the double helical fastener 110 is also longitudinally collapsible and expandable and its final pitch is dependent upon the gap 112 existing between the most distal coils 114, 115 of the fastener 110 and their adjacent coils.
  • Regarding the proximal [0066] 118 and distal 120 ends of the double helical fastener 110, they comprise structure to drive the fastener into tissue as well as tissue piercing structures. The proximal end 118 has a connector bar 122 sectioning the diameter of the fastener that connects one helical coil to another and functions to receive and transmit longitudinal forces. The distal end 120 terminates with two points 124, 125 for piercing and facilitating the implantation of the fastener 110 into tissue.
  • As may be appreciated by comparing FIGS. [0067] 2-2D with FIGS. 3-3D, it is contemplated that the double helical fastener 110 have a full turn design (FIGS. 2-2D) as well as a half turn design (FIGS. 3-3D). It is to be understood, however, that the designs having more than one turn and having other increments of turns are contemplated. It is the applicator that will determine the required number of turns for a specific fastener 110.
  • In yet another embodiment of the surgical fastener, as shown in FIG. 4, the double helical fastener [0068] 110 is provided with a pivot post 130 having a pointed terminal end 132. The pivot post 130 of this embodiment operates to provide the fastener 110 with a stabilizing element so that, as the fastener 110 is being turned, the helical coils cooperatively enter the tissue.
  • The applicator [0069] 12 (FIG. 5) comprises a proximal portion 28 having a handle 30 and an actuator 32 and a cooperating elongated distal portion or cannula 34 housing a plurality of fasteners. In general, through the manipulation of the actuator 32, the fasteners are ejected, one by one, out of a distal portion 34 and into body tissue. The applicator 12, hereinafter described in more detail, is equally proficient in driving each of the embodiments of fasteners set forth above into tissue.
  • In more detail (see FIGS. 6 and 6A), the distal portion [0070] 34 comprises an outer tube 36 housing a rotator 38, a lock/clip indicator 40 and a load spring 42. Extending longitudinally along the rotator 38 is a groove 44 which operates to receive the most proximal coil sectioning the fastener. Although FIG. 6 shows only a single fastener (having a single helical design) retained by the rotator 38, it is to be appreciated that the rotator 38 may receive a plurality of fasteners (having a single or double helical design), wherein each fastener has its last coil positioned within the rotator groove 44. Moreover, although not depicted in FIG. 3, it is also contemplated that rather than embodying a groove, the rotator 38 has a crosssectional profile approximately a “D”, wherein the flat portion operates to engage the coil sectioning the fasteners. Irrespective of the configuration of the rotator, however, the rotator is to embody structure functioning to engage a plurality of fasteners and to facilitate turning them into tissue.
  • It is also to be appreciated that load spring [0071] 42 applies a force through the lock clip indicator 40 to bias the plurality of fasteners distally. The lock clip/indicator 40 may comprise a simple washer sized and shaped to engage the fasteners and rotator 38 as well as to receive forces from the load spring 42. Additionally, lock/clip indicator 40 serves as a jam stop to prevent further actuation by rotator 38 upon discharge of all fasteners by mating with, or abutting against, structure comprising the terminal end 50 and preventing further rotation. Lock/indicator 40 can be made of a color (or shape) to serve as an empty indicator notifying the user that no more fasteners are available. Other embodiments of the indicator 40 may be utilized as long as they function to transmit forces to bias the fasteners distally. The load spring 42 is to be retained within the outer tube 36 and to have physical characteristics such that sufficient forces may be applied through a front end 43 to a last remaining fastener contained within the applicator 12. A back end (not shown) of the load spring 42 may be placed against any stationery structure within the outer tube 36, thereby providing a foundation against which the spring 42 may be compressed. In a preferred embodiment, the load spring 42 extends substantially the length of the distal portion 34.
  • In the preferred embodiment (FIGS. 7 and 7A), the outer tube [0072] 36 is configured with a thread form 201 comprising an interlock spring 203 fixedly retained within the outer tube 36 and extending substantially the length thereof. The interlock spring 203 may be fixedly retained within the outer tube 36 by ensuring a tight interference between the parts or the interlock spring may be spot welded or equivalently bonded within the outer tube. The thread form 201 operates to guide the fasteners through the distal portion 34 and to eject them from the applicator 12.
  • In another embodiment of the applicator [0073] 12 (FIGS. 8 and 8A), attached at a terminal end 46 of the distal portion 34 may be a nose piece 48. The nose piece 48 may further comprise a protrusion 50 extending perpendicularly and towards a longitudinal axis 52 of the distal portion 34. This nose piece protrusion 50 also functions to engage the surgical fasteners and to force them from the terminal end 46 of the distal portion 34 as well as engaging lock/clip indicator 40 as described above.
  • In other embodiments of the applicator [0074] 12, the distal portion embodies other structure or thread forms functioning to engage, the surgical fasteners and guide them out of the applicator and into tissue (See FIGS. 9-14). In FIGS. 9 and 9A, the outer tube 36 is rolled at its terminal end 46 and a 180° portion of the rolled terminal end is cut away. The remaining rolled portion engages the fastener while the portion cut away provides an exit for the fasteners. The embodiment depicted in FIGS. 10 and 10A is similar to that of FIGS. 9 and 9A, the difference being that instead of removing a portion of the rolled terminal end 46, it is stamped or deformed to thereby provide an exit. FIGS. 11 and 11A show yet another embodiment, wherein two longitudinally spaced apart stabilizing points 301, 302 are formed 180° from each other within the outer tube. These stabilizing points also operate to engage the fastener and guide it into tissue. Turning to FIGS. 12, 12A, 13 and 14, they each comprise a terminal end 46 formed with threads which operate to engage and eject a fastener. In FIGS. 12 and 12A are depicted threads machined or formed solely within the inside of the outer tube. FIG. 13 shows an internally threaded sleeve attached to the outside of the terminal end 46 of the outer tube 36. FIG. 14 illustrates an applicator 12 provided with a terminal end 46 deformed so as to have internal and external threaded structures. Irrespective of the design chosen for the terminal end of the applicator, however, each of the designs are effective with a relatively small overall outer diameter, i.e., on the order of 5 mm.
  • In order to eject surgical fasteners from the distal portion [0075] 34, the actuator 32 functions to turn the rotator 38. As the rotator turns, the distal end 22 of a fastener is threaded out of the terminal end 46 of the applicator 12 (see FIG. 5).
  • In the preferred embodiment of the proximal portion [0076] 28 of the applicator 12 (See FIG.5), a lever 54 is pivotally connected about a midpoint 56 to the handle 30. A first end 58 of the lever 54 is to be configured for gripping by hand. A second end 60 of the lever is to be adapted to pivotally engage a nut driver 62.
  • The nut driver [0077] 62 of the applicator 12 travels upon a high helix lead screw 64 which is rotatably mounted within the proximal portion 28. In the preferred embodiment, a longitudinal axis of the high helix lead screw 64 is coaxial with the longitudinal axis 52 extending through the distal portion 34 of the applicator 12. Upon manipulation of the lever 54, the nut driver 62 travels along the lead screw 64 causing it to rotate through a connection of the lead screw 64 to the rotator 38, the action of the lead screw causes the rotator to rotate. The lead screw 64 may be connected to the rotator 38 by any conventional means. For instance, the lead screw 64 can have an internal bore receiving and engaging an end of the rotator 38. Further, the length of travel of the nut driver 62 along the lead screw 64 is chosen such that it causes the rotator to rotate a predetermined number of times so that a single helical fastener 10 is ejected from the applicator 12.
  • Additionally, in the preferred embodiment, the lever further comprises a midsection extension [0078] 66. Pivotally attached to the midsection extension 66 of the lever 54 is contemplated to be a spring loaded pawl 68 adapted to releasably engage gear teeth 70 formed in the interior of the handle 30. Spring loaded pawl 68 is configured to prohibit the lever 54 from backstroking until it has been completely depressed. Upon complete depression of the lever 54, the pawl 68 clears the gear teeth 70 and the spring biasing the pawl 68 rotates the pawl 68 away from the teeth 70, thereby allowing the lever 54 to return to its undepressed condition.
  • In operation, upon complete depression of the lever [0079] 54, the nut driver 62 travels a pre-determined distance along the lead screw 64, causing the rotator 38 to rotate a pre-determined number of revolutions corresponding to a number of turns of a particular helical fastener 10. As the rotator 38 rotates, the fasteners retained by the rotator also rotate and the coils of the most distal fastener are threaded out of the terminal end 46 of the applicator 12 and into tissue. Moreover, where the lever 54 is only partially depressed, the spring loaded pawl 68 operates to hold the lever 54 stationery and will continue to function to hold the lever 54 stationery until the lever 54 has been completely depressed. In this way, the delivery of fasteners into body tissue is controlled so that only a single fastener may be completely ejected out of the applicator 12 and pressed into body tissue at a time.
  • In the preferred embodiment, the proximal portion [0080] 28 is fabricated to have a reusable handle that can be re-sterilized, and the distal portion is made disposable. Thus, upon discharge of all the fasteners 10 from distal portion 34, the distal portion would be discarded and replaced. The handle could be reused up to a limited number of procedures.
  • In another embodiment of the proximal portion [0081] 328, of the applicator 312 (FIG. 15), a lever 354 is pivotally connected at a first end 355 to the handle 330 and biased to its undepressed position by a spring 357. The mid-section 358 of the lower 354 is configured for gripping by hand. A second end 360 of the lever is to be adapted to pivotally engage a nut drive 362.
  • The nut driver [0082] 362 of the applicator 312 travels along a high helix lead screw 364 which is rotatably mounted within the proximal portion 328. Upon manipulation of the lever 354, the nut driver travels along the lead screw 364 causing it to rotate and, through a clutch assembly or a releasable connection of the lead screw 364 to the rotator 38, the action of the lead screw causes the rotator to rotate.
  • Further, the lever [0083] 354, has a mid-section extension 366 that cooperates with a spring biased latch pawl mechanism 368 fixed to the handle adapted to releasably engage teeth 370 formed on the mid-section extension 366. The spring biased latch pawl is configured to prohibit the lever 354 from backstroking until it has been completely depressed. Upon complete depression of the lever 354, the latch pawl 368 clears the mid-section teeth 370 and the spring biased latch pawl 368 rotates away from the teeth, thereby allowing the lever 354 to return to its undepressed condition.
  • As stated, there is a releasable connection between the lead screw [0084] 364 and the rotator. The releasable connection provides the applicator with means to disengage the distal portion of the applicator from the proximal portion. In this way, the proximal portion can be re-used with various different designs of the proximal portion. Further, while the lever 354 is being depressed, the clutch assembly or releasable connection functions to transfer the rotation of the lead screw 364 to the rotator 38, thereby causing the rotator to rotate. Additionally, upon complete depression of the lever, the clutch assembly operates to allow relative motion of the lead screw 364 and the rotator.
  • one such releasable connection contemplated is a conventional ratchet mechanism. As shown in FIGS. [0085] 16-16D, the distal end 370 of the lead screw 364 has a connecting surface 372 equipped with leaf springs 374, 376 each having an engaging face 377 and an internal bore 378 existing coaxially with a longitudinal axis of the lead screw. The proximal end 380 of the rotator 38 has a cooperating connecting surface 382 having ridges 384 for releasable engagement with the leaf springs 374, 376 and an extension 386 adapted to fit within the internal bore of the lead screw connecting surface. As may be appreciated from the FIGS., as the lead screw turns so that the ridges 384 contact the engaging faces 377 of the leaf springs 374, 376, the rotation of the lead screw 364 will cause the rotator 38 to likewise rotate. Where the lead screw is turned in the opposite direction, the ridges 384 will not engage the engaging face of the leaf springs and the motion of the lead screw 384 will not be transferred to the rotator 38.
  • In this embodiment, upon complete depression of the lever [0086] 354, the nut driver 362 travels a pre-determined distance along the lead screw 364, causing the rotator 38 to rotate a pre-determined number of revolutions. As the rotator 38 rotates, the fasteners retained by the rotator also rotate and the coils of the most distal fasteners are threaded out of the applicator and into the tissue. At this point, the latch pawl mechanism 368 disengages from the teeth 370 and the lever 354 is returned to its undepressed position by spring 357. As with the previous embodiment of the proximal portion 28, the proximal portion of this embodiment functions to allow only a single fastener to be completely ejected from the applicator and be pressed into body tissue at a time.
  • In other embodiments, means to cause the rotator to rotate may comprise a single knob connected to a rotator which can be turned by hand. Additionally, the revolving means may include a rack and gear structure or a set of beveled gears. Further, instead of comprising a groove, the rotator may be internally threaded, wherein the threaded portions function to house as well as advance the helical fasteners [0087] 10. Irrespective of the means or structure employed, however, it is contemplated that the number of revolutions of the rotator be set to a pre-determined parameter so that the delivery of helical fasteners to tissue may be controlled.
  • From the foregoing, it will be appreciated that the helical fastener in applicator of the present invention functions to securely attach a fastener with high retentive surface area to tissue from one direction through the utilization of an applicator having a simple design. It is also to be appreciated that the present invention may be utilized in a number of applications including ligating tissue, hernia mesh repair, bladder neck suspension, and in conjunction with implant drug delivery systems or procedures involving positioning of surgical or implantable devices in patient. [0088]
  • While several particular forms of the invention have been illustrated and described, it will also be apparent that various modifications can be made without departing from the spirit and scope of the invention. [0089]
  • Thus, it should be understood that various changes in form, detail and application of the present invention may be made without departing from the spirit and scope of this invention. [0090]

Claims (59)

    What is claimed is:
  1. 1. A fastener for ligating tissue or attaching an implantable device, the fastener comprising:
    a continuous helical coil having a distal end and a proximal end;
    a first helical coil section at said distal end;
    tissue piercing means on said first coil; and
    means for inserting said continuous helical coil so that said continuous helical coil penetrates tissue to ligate the tissue to position and attach the implantable device.
  2. 2. The fastener of claim 1, wherein said tissue piercing means is a point formed at a terminal end of said first helical coil section.
  3. 3. The fastener of claim 2, wherein said point of said first helical coil section and an adjacent coil section define a gap, said gap adapted to determine depth of penetration and pitch of the fastener in tissue and retentive strength of the fastener to tissue.
  4. 4. The fastener of claim 1, wherein said continuous helical coil has a uniform pitch between coils.
  5. 5. The fastener of claim 1, wherein said continuous helical coil has a pitch between coils that can be varied by an applicator.
  6. 6. The fastener of claim 1, wherein said continuous helical coil has a pitch sufficient to entrap tissue between coils.
  7. 7. The fastener of claim 1, wherein said continuous helical coil has a pitch that can be increased as said fastener is inserted into the tissue.
  8. 8. The fastener of claim 1, wherein said continuous helical coil has a pitch of 0.050 inches.
  9. 9. The fastener of claim 1, wherein said continuous helical coil has a pitch range from 0 to a maximum of 3.0 times a diameter of said helical coil.
  10. 10. The fastener of claim 1, wherein said means for inserting said continuous helical coil is a T-bar at said proximal end.
  11. 11. The fastener of claim 10, wherein a rotational force and a longitudinal force is applied to said T-bar by an applicator that rotates and delivers said continuous helical coil into tissue.
  12. 12. The fastener of claim 1, wherein said continuous helical coil is sized to fit within a cannula having a diameter of at least 1 mm.
  13. 13. The fastener of claim 1, wherein at least a portion of said continuous helical coil is coated with a biocompatible lubricious material for facilitating delivery of the fastener into tissue.
  14. 14. The fastener of claim 1, wherein said continuous helical coil is made from absorbable material.
  15. 15. The fastener of claim 1, wherein said continuous helical coil is made from a metallic material selected from the group of materials consisting essentially of titanium, titanium alloys, stainless steel and nickel chrome alloys.
  16. 16. The fastener of claim 1, wherein said continuous helical coil is made from a polymeric material selected from the group of materials consisting essentially of plastics, liquid crystal polymers, HDPE, polyglycolic acid, and polyglycolid hydroxgacetic acid.
  17. 17. The fastener of claim 1, wherein said continuous helical coil is longitudinally collapsible and expandable.
  18. 18. The fastener of claim 1, further comprising one or more barbs projecting in reverse direction and positioned proximate to said tissue piercing means.
  19. 19. A fastener for ligating tissue or for attaching an implantable device, the fastener comprising:
    a continuous helical coil having a distal end and a proximal end;
    a point on said distal end for piercing the tissue;
    a first helical coil section adjacent said distal end and having a gap between said point and said first helical coil section; and
    a T-bar section at said proximal end for engagement with an applicator for inserting said helical coil through the tissue to position and attach the implantable device.
  20. 20. The fastener of claim 19, wherein said gap is adapted to determine depth of penetration and pitch of the fastener in tissue and retentive strength of the fastener to tissue.
  21. 21. The fastener of claim 19, wherein said continuous helical coil has a uniform pitch between coils.
  22. 22. The fastener of claim 19, wherein said continuous helical coil has a pitch between coils that can be varied by the applicator.
  23. 23. The fastener of claim 19, wherein said continuous helical coil has a pitch that can be increased as the fastener is inserted into the tissue.
  24. 24. The fastener of claim 19, wherein said continuous helical coil is made from absorbable material.
  25. 25. The fastener of claim 19, wherein said continuous helical coil is made from a metallic material selected from the group of materials consisting essentially of titanium, titanium alloys, stainless steel and nickel chrome alloys.
  26. 26. The fastener of claim 19, wherein said continuous helical coil is made from a polymeric material selected from the group of materials consisting essentially of plastics, liquid crystal polymers, HDPE, polyglycolic acid and polyglycolid hydroxgacetic acid.
  27. 27. The fastener of claim 19, wherein said continuous helical coil is longitudinally collapsible and expandable.
  28. 28. The fastener of claim 19, further comprising one or more barbs projecting in reverse direction and positioned proximate to said point.
  29. 29. A fastener for ligating tissue or for attaching an implantable device, the fastener comprising:
    a continuous double helical coil having a distal end and a proximal end;
    said distal end terminating with dual points each for piercing the tissue;
    dual first helical coil sections adjacent said distal end each being associated with one of said dual points and each defining a gap therebetween; and
    a connecting bar at said proximal end for engagement with an applicator for inserting said double helical coil through the tissue to position and attach the implantable device.
  30. 30. The fastener of claim 29, wherein said gap is adapted to determine depth of penetration and pitch of the fastener in tissue and retentive strength of the fastener to tissue.
  31. 31. The fastener of claim 29, wherein said continuous double helical coil has uniform pitch between coils.
  32. 32. The fastener of claim 29, wherein said continuous double helical coil has a pitch between coils that can be varied by the applicator.
  33. 33. The fastener of claim 29 wherein said continuous double helical has a pitch that can be increased as the fastener is inserted into the tissue.
  34. 34. The fastener of claim 29, where said continuous double helical coil is made from absorbable material.
  35. 35. The fastener of claim 29, wherein said continuous double helical coil is mad e from a metallic material selected from the group of materials consisting essentially of titanium, titanium alloys, stainless steel and nickel chrome alloys.
  36. 36. The fastener of claim 29, wherein said continuous double helical coil is made from a polymeric material selected from the group of materials consisting essentially of plastics, liquid crystal polymers, HDPE, polyglycolic acid and polyglycolid hydroxgacetic acid.
  37. 37. The fastener of claim 29, wherein said continuous double helical coil is longitudinally collapsible and expandable.
  38. 38. The fastener of claim 29, further comprising a pivot post extending from said connecting bar and toward said distal end, said pivot post having a pointed terminal end.
  39. 39. The fastener of claim 29, further comprising one or more barbs projecting in reverse direction and positioned proximate to said dual points.
  40. 40. An applicator for attaching fasteners to body tissue comprising:
    a distal portion having an elongate outer tube, a connecting end and a terminal end;
    a proximal portion having a handle and an actuator, said proximal portion attached to said connecting end of said distal portion;
    a rotator contained in said outer tube;
    said rotator adapted to receive a plurality of fasteners and adapted to cooperate with said actuator; and
    means for threading and ejecting the fasteners out of said terminal end.
  41. 41. The applicator of claim 40, further comprising:
    a lock/clip indicator adapted to engage said plurality of fasteners; and
    a load spring adapted to apply longitudinal forces against said lock/clip indicator and to bias said plurality of fasteners toward said terminal end.
  42. 42. The applicator of claim 41, wherein said lock/clip indicator is configured to prevent actuation of said actuator upon discharge of said plurality of fasteners from the applicator.
  43. 43. The applicator of claim 40, wherein a groove extends longitudinally along substantially the length of said rotator, said groove adapted to receive coils of said plurality of fasteners.
  44. 44. The applicator of claim 40, wherein said rotator has a cross-sectional profile approximating a D-shape and is adapted to receive coils of said plurality of fasteners.
  45. 45. The applicator of claim 40, wherein said threading and ejecting means is a thread form contained in an interior of said terminal end adapted to engage said plurality of fasteners.
  46. 46. The applicator of claim 45, wherein said thread form is an interlock spring fixedly retained in said interior of said terminal end.
  47. 47. The applicator of claim 40, wherein said threading and ejecting means a nose piece attached to said terminal end, said nose piece having structure projecting perpendicularly toward a longitudinal axis of said outer tube and adapted to engage said plurality of fasteners.
  48. 48. The applicator of claim 40, wherein said distal portion and said proximal position are releasably secured together.
  49. 49. The applicator of claim 48, wherein said distal portion is disposable and said proximal portion is reusable.
  50. 50. The applicator of claim 40, wherein said actuator includes:
    a lever having a first end and a second end, said lever pivotally attached about a midpoint to said handle;
    said first end of said lever adapted to be gripped by hand;
    a lead screw rotatably attached to an interior of said handle;
    a nut driver, said second end of said lever pivotally attached to said nut driver, said nut driver adapted to travel along said lead screw, thereby turning said lead screw; and
    said lead screw attached to said rotator so that as the lever is depressed by hand the nut driver will travel along the lead screw toward said rotator thereby turning said rotator in the process.
  51. 51. The applicator of claim 50, wherein said lead screw is a high helix lead screw.
  52. 52. The applicator of claim 50, wherein said lever has a midsection extension.
  53. 53. The applicator of claim 52, further comprising gear teeth formed within said interior of said handle.
  54. 54. The applicator of claim 53, further comprising a spring loaded pawl pivotally attached to said midsection extension and adapted to engage said gear teeth.
  55. 55. The applicator of claim 40, wherein said actuator includes:
    a lever having a first end, a midsection, and a second end, said first end pivotally attached to said handle, said midsection adapted to be gripped by hand;
    a lead screw rotatably attached to an interior of said handle;
    a nut driver, said second end pivotally attached to said nut driver, said nut driver adapted to travel along said lead screw, thereby turning said lead screw; and
    means for said lead screw to releasably engage said rotator so that as the lever is depressed by hand, the nut driver will travel along the lead screw toward said rotator thereby turning said rotator in the process and so that when the lever is returned to its undepressed position, the lead screw will rotate in the reverse direction and independently of the rotator which remains stationary.
  56. 56. The applicator of claim 55, wherein said lead screw is a high helix lead screw.
  57. 57. The applicator of claim 55, wherein said releasable engagement means is a ratchet mechanism.
  58. 58. The applicator of claim 55, wherein said lever has a mid-section extension, formed in said mid-section extension are a plurality of teeth.
  59. 59. The application of claim 58, further comprising a latch pawl cooperating with said teeth to prohibit said lever from backstroking until it has been completely depressed.
US09968100 1994-08-05 2001-10-01 Surgical helical fastener with applicator Expired - Fee Related US6562051B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US08286878 US5582616A (en) 1994-08-05 1994-08-05 Surgical helical fastener with applicator
US08499279 US6296656B1 (en) 1994-08-05 1995-07-07 Surgical helical fastener with applicator
US09968100 US6562051B1 (en) 1994-08-05 2001-10-01 Surgical helical fastener with applicator

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09968100 US6562051B1 (en) 1994-08-05 2001-10-01 Surgical helical fastener with applicator
US10330903 US6884248B2 (en) 1994-08-05 2002-12-27 Surgical helical fastener with applicator
US10755427 US8579919B2 (en) 1994-08-05 2004-01-12 Surgical helical fastener with applicator
US11978893 US20080097523A1 (en) 1994-08-05 2007-10-30 Surgical helical fastener with applicator

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US08499279 Continuation US6296656B1 (en) 1994-08-05 1995-07-07 Surgical helical fastener with applicator

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10330903 Continuation US6884248B2 (en) 1994-08-05 2002-12-27 Surgical helical fastener with applicator

Publications (2)

Publication Number Publication Date
US20020013605A1 true true US20020013605A1 (en) 2002-01-31
US6562051B1 US6562051B1 (en) 2003-05-13

Family

ID=23100566

Family Applications (9)

Application Number Title Priority Date Filing Date
US08286878 Expired - Lifetime US5582616A (en) 1994-08-05 1994-08-05 Surgical helical fastener with applicator
US08499279 Expired - Lifetime US6296656B1 (en) 1994-08-05 1995-07-07 Surgical helical fastener with applicator
US08772143 Expired - Lifetime US5810882A (en) 1994-08-05 1996-12-20 Surgical helical fastener with applicator and method of use
US08812958 Expired - Lifetime US5964772A (en) 1994-08-05 1997-03-05 Applicator for attaching fasteners to tissue
US08812959 Expired - Lifetime US5824008A (en) 1994-08-05 1997-03-05 System for applying fasteners to tissue
US09968100 Expired - Fee Related US6562051B1 (en) 1994-08-05 2001-10-01 Surgical helical fastener with applicator
US10330903 Expired - Fee Related US6884248B2 (en) 1994-08-05 2002-12-27 Surgical helical fastener with applicator
US10755427 Expired - Fee Related US8579919B2 (en) 1994-08-05 2004-01-12 Surgical helical fastener with applicator
US11978893 Abandoned US20080097523A1 (en) 1994-08-05 2007-10-30 Surgical helical fastener with applicator

Family Applications Before (5)

Application Number Title Priority Date Filing Date
US08286878 Expired - Lifetime US5582616A (en) 1994-08-05 1994-08-05 Surgical helical fastener with applicator
US08499279 Expired - Lifetime US6296656B1 (en) 1994-08-05 1995-07-07 Surgical helical fastener with applicator
US08772143 Expired - Lifetime US5810882A (en) 1994-08-05 1996-12-20 Surgical helical fastener with applicator and method of use
US08812958 Expired - Lifetime US5964772A (en) 1994-08-05 1997-03-05 Applicator for attaching fasteners to tissue
US08812959 Expired - Lifetime US5824008A (en) 1994-08-05 1997-03-05 System for applying fasteners to tissue

Family Applications After (3)

Application Number Title Priority Date Filing Date
US10330903 Expired - Fee Related US6884248B2 (en) 1994-08-05 2002-12-27 Surgical helical fastener with applicator
US10755427 Expired - Fee Related US8579919B2 (en) 1994-08-05 2004-01-12 Surgical helical fastener with applicator
US11978893 Abandoned US20080097523A1 (en) 1994-08-05 2007-10-30 Surgical helical fastener with applicator

Country Status (7)

Country Link
US (9) US5582616A (en)
EP (10) EP0835642B1 (en)
JP (2) JP3691851B2 (en)
CA (3) CA2196905C (en)
DE (13) DE69527989T2 (en)
ES (7) ES2183081T3 (en)
WO (1) WO1996003925A1 (en)

Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004096059A1 (en) * 2003-04-28 2004-11-11 Erwin De Winter Screw-device for anastomosis
US20050059956A1 (en) * 2000-08-30 2005-03-17 The Johns Hopkins University Devices for intraocular drug delivery
US20050277959A1 (en) * 2004-05-26 2005-12-15 Idx Medical, Ltd. Apparatus and methods for occluding a hollow anatomical structure
US20070250064A1 (en) * 2006-04-21 2007-10-25 Davol, Inc. Method and apparatus for surgical fastening
US20090012545A1 (en) * 2005-07-14 2009-01-08 Idx Medical, Ltd. Apparatus and Methods for Occluding a Hallow Anatomical Structure
US20090114701A1 (en) * 2007-11-06 2009-05-07 Tyco Healthcare Group Lp Coated Surgical Staples and an Illuminated Staple Cartridge for a Surgical Stapling Instrument
US20100010520A1 (en) * 2008-07-11 2010-01-14 Olympus Medical Systems Corp. Tissue fastener
US20100179570A1 (en) * 2009-01-13 2010-07-15 Salvatore Privitera Apparatus and methods for deploying a clip to occlude an anatomical structure
US7758612B2 (en) 2004-04-27 2010-07-20 Tyco Healthcare Group Lp Surgery delivery device and mesh anchor
US20100189765A1 (en) * 2008-11-26 2010-07-29 Erickson Signe R Implantable ocular drug delivery device and methods
US20110022065A1 (en) * 2004-04-27 2011-01-27 Shipp John I Absorbable anchor for hernia mesh fixation
WO2011015789A1 (en) * 2009-08-06 2011-02-10 Textile Hi-Tec (T.H.T.) Fastener for a mechanical suture
US20110295282A1 (en) * 2010-05-26 2011-12-01 Tyco Healthcare Group Lp Fastener and drive method for soft tissue repair
US8162958B2 (en) 2008-07-11 2012-04-24 Olympus Medical Systems Corp. Tissue fastening tool and applicator for indwelling the same within body, and tissue fastening method through natural orifice
US8636754B2 (en) 2010-11-11 2014-01-28 Atricure, Inc. Clip applicator
US8828026B2 (en) 2008-07-11 2014-09-09 Olympus Medical Systems Corp. Tissue fastening apparatus
US8852218B2 (en) 2008-07-21 2014-10-07 AtriCore, Inc. Apparatus and methods for occluding an anatomical structure
US8876820B2 (en) 2004-10-20 2014-11-04 Atricure, Inc. Surgical clamp
US8942829B2 (en) 2011-01-20 2015-01-27 Medtronic, Inc. Trans-septal lead anchoring
US20150045612A1 (en) * 2013-08-12 2015-02-12 Boston Scientific Scimed, Inc. Wire coil tissue fixation device
US9017349B2 (en) 2010-10-27 2015-04-28 Atricure, Inc. Appendage clamp deployment assist device
US9066741B2 (en) 2010-11-01 2015-06-30 Atricure, Inc. Robotic toolkit
US9265486B2 (en) 2011-08-15 2016-02-23 Atricure, Inc. Surgical device
US20160051811A1 (en) * 2014-08-21 2016-02-25 Biotronik Se & Co. Kg Medical implant with a fixing device
US9271725B2 (en) 2006-07-18 2016-03-01 Davol, Inc. Method and apparatus for surgical fastening
US9282973B2 (en) 2012-01-20 2016-03-15 Atricure, Inc. Clip deployment tool and associated methods
US9408659B2 (en) 2007-04-02 2016-08-09 Atricure, Inc. Surgical instrument with separate tool head and method of use
US10098640B2 (en) 2001-12-04 2018-10-16 Atricure, Inc. Left atrial appendage devices and methods

Families Citing this family (671)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6171338B1 (en) * 1988-11-10 2001-01-09 Biocon, Oy Biodegradable surgical implants and devices
US7384423B1 (en) 1995-07-13 2008-06-10 Origin Medsystems, Inc. Tissue dissection method
US6451024B1 (en) 1995-06-14 2002-09-17 Dexterity Surgical, Inc. Surgical method for treating urinary incontinence, and apparatus for use in same
US5662683A (en) * 1995-08-22 1997-09-02 Ortho Helix Limited Open helical organic tissue anchor and method of facilitating healing
WO1997032839A1 (en) * 1996-03-04 1997-09-12 Molecular Design International, Inc. 9-cis-retinoic acid esters and amides and uses thereof
US5810851A (en) * 1996-03-05 1998-09-22 Yoon; Inbae Suture spring device
US5782844A (en) * 1996-03-05 1998-07-21 Inbae Yoon Suture spring device applicator
US7611521B2 (en) 1996-09-13 2009-11-03 Tendon Technology, Ltd. Apparatus and methods for tendon or ligament repair
US6984241B2 (en) * 1996-09-13 2006-01-10 Tendon Technology, Ltd. Apparatus and methods for tendon or ligament repair
EP0934024B1 (en) * 1996-09-20 2006-08-30 United States Surgical Corporation Coil fastener applier
US5830221A (en) * 1996-09-20 1998-11-03 United States Surgical Corporation Coil fastener applier
US7591846B2 (en) 1996-11-04 2009-09-22 Boston Scientific Scimed, Inc. Methods for deploying stents in bifurcations
US8298280B2 (en) 2003-08-21 2012-10-30 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US6599316B2 (en) 1996-11-04 2003-07-29 Advanced Stent Technologies, Inc. Extendible stent apparatus
US6835203B1 (en) 1996-11-04 2004-12-28 Advanced Stent Technologies, Inc. Extendible stent apparatus
US8211167B2 (en) 1999-12-06 2012-07-03 Boston Scientific Scimed, Inc. Method of using a catheter with attached flexible side sheath
US6325826B1 (en) 1998-01-14 2001-12-04 Advanced Stent Technologies, Inc. Extendible stent apparatus
US6692483B2 (en) 1996-11-04 2004-02-17 Advanced Stent Technologies, Inc. Catheter with attached flexible side sheath
US5972001A (en) * 1996-11-25 1999-10-26 Yoon; Inbae Method of ligating anatomical tissue with a suture spring device
US6071292A (en) * 1997-06-28 2000-06-06 Transvascular, Inc. Transluminal methods and devices for closing, forming attachments to, and/or forming anastomotic junctions in, luminal anatomical structures
US5957940A (en) * 1997-06-30 1999-09-28 Eva Corporation Fasteners for use in the surgical repair of aneurysms
US5997556A (en) * 1997-06-30 1999-12-07 Eva Corporation Surgical fastener
US5944750A (en) * 1997-06-30 1999-08-31 Eva Corporation Method and apparatus for the surgical repair of aneurysms
US6004333A (en) * 1997-10-31 1999-12-21 Ethicon Endo-Surgery, Inc. Prosthetic with collagen for tissue repair
US5972007A (en) * 1997-10-31 1999-10-26 Ethicon Endo-Surgery, Inc. Energy-base method applied to prosthetics for repairing tissue defects
US6911032B2 (en) * 1999-11-18 2005-06-28 Scimed Life Systems, Inc. Apparatus and method for compressing body tissue
CA2265136C (en) * 1998-03-13 2008-09-09 Juan Carlos Parodi Endovascular device for application of prostheses with sutures
US7591842B2 (en) * 1998-03-13 2009-09-22 Aptus Endosystems, Inc. Endovascular prosthesis with suture holder
US5947983A (en) * 1998-03-16 1999-09-07 Boston Scientific Corporation Tissue cutting and stitching device and method
US6241740B1 (en) * 1998-04-09 2001-06-05 Origin Medsystems, Inc. System and method of use for ligating and cutting tissue
US6176877B1 (en) 1998-04-20 2001-01-23 St. Jude Medical, Inc. Two piece prosthetic heart valve
US7722667B1 (en) 1998-04-20 2010-05-25 St. Jude Medical, Inc. Two piece bioprosthetic heart valve with matching outer frame and inner valve
US6074418A (en) * 1998-04-20 2000-06-13 St. Jude Medical, Inc. Driver tool for heart valve prosthesis fasteners
US6382214B1 (en) * 1998-04-24 2002-05-07 American Medical Systems, Inc. Methods and apparatus for correction of urinary and gynecological pathologies including treatment of male incontinence and female cystocele
US6740098B2 (en) 1998-05-11 2004-05-25 Surgical Connections, Inc. Surgical stabilizer devices and methods
US6517566B1 (en) * 1998-05-11 2003-02-11 Surgical Connections, Inc. Devices and methods for treating e.g. urinary stress incontinence
US20050021085A1 (en) * 1998-05-11 2005-01-27 Surgical Connections, Inc. Surgical stabilizer devices and methods
US6113609A (en) 1998-05-26 2000-09-05 Scimed Life Systems, Inc. Implantable tissue fastener and system for treating gastroesophageal reflux disease
US6113611A (en) * 1998-05-28 2000-09-05 Advanced Vascular Technologies, Llc Surgical fastener and delivery system
US6726704B1 (en) 1998-05-29 2004-04-27 By-Pass, Inc. Advanced closure device
WO1999062415A1 (en) 1998-05-29 1999-12-09 By-Pass, Inc. Methods and devices for vascular surgery
US7063711B1 (en) 1998-05-29 2006-06-20 By-Pass, Inc. Vascular surgery
US6607541B1 (en) 1998-06-03 2003-08-19 Coalescent Surgical, Inc. Tissue connector apparatus and methods
US6641593B1 (en) 1998-06-03 2003-11-04 Coalescent Surgical, Inc. Tissue connector apparatus and methods
US6945980B2 (en) 1998-06-03 2005-09-20 Medtronic, Inc. Multiple loop tissue connector apparatus and methods
US6976957B1 (en) 1998-06-22 2005-12-20 Origin Medsystems, Inc. Cannula-based surgical instrument and method
US6830546B1 (en) 1998-06-22 2004-12-14 Origin Medsystems, Inc. Device and method for remote vessel ligation
US7326178B1 (en) 1998-06-22 2008-02-05 Origin Medsystems, Inc. Vessel retraction device and method
EP0979635A2 (en) 1998-08-12 2000-02-16 Origin Medsystems, Inc. Tissue dissector apparatus
US7011668B2 (en) * 2001-07-23 2006-03-14 Dvl Acquistion Sub, Inc. Surgical suturing instrument and method of use
US6527785B2 (en) * 1999-08-03 2003-03-04 Onux Medical, Inc. Surgical suturing instrument and method of use
US6332889B1 (en) * 1998-08-27 2001-12-25 Onux Medical, Inc. Surgical suturing instrument and method of use
US20090112302A1 (en) * 2001-11-28 2009-04-30 Josh Stafford Devices, systems, and methods for endovascular staple and/or prosthesis delivery and implantation
US7637932B2 (en) * 2001-11-28 2009-12-29 Aptus Endosystems, Inc. Devices, systems, and methods for prosthesis delivery and implantation
US9320503B2 (en) * 2001-11-28 2016-04-26 Medtronic Vascular, Inc. Devices, system, and methods for guiding an operative tool into an interior body region
WO2000016701A1 (en) * 1998-09-18 2000-03-30 United States Surgical Corporation Endovascular fastener applicator
US7491232B2 (en) * 1998-09-18 2009-02-17 Aptus Endosystems, Inc. Catheter-based fastener implantation apparatus and methods with implantation force resolution
US6951564B2 (en) * 1998-10-23 2005-10-04 United States Surgical Corporation Site marker device
US6656192B2 (en) 1998-09-25 2003-12-02 United States Surgical Corporatioin Site marker device
EP1133261A4 (en) * 1998-11-18 2005-01-05 Gen Surgical Innovations Inc Helical fastener and applicator for surgical procedures
US7344557B2 (en) 2003-11-12 2008-03-18 Advanced Stent Technologies, Inc. Catheter balloon systems and methods
US6514265B2 (en) 1999-03-01 2003-02-04 Coalescent Surgical, Inc. Tissue connector apparatus with cable release
US8118822B2 (en) 1999-03-01 2012-02-21 Medtronic, Inc. Bridge clip tissue connector apparatus and methods
US6613059B2 (en) 1999-03-01 2003-09-02 Coalescent Surgical, Inc. Tissue connector apparatus and methods
US6416486B1 (en) 1999-03-31 2002-07-09 Ethicon Endo-Surgery, Inc. Ultrasonic surgical device having an embedding surface and a coagulating surface
US6287344B1 (en) 1999-03-31 2001-09-11 Ethicon Endo-Surgery, Inc. Method for repairing tissue defects using an ultrasonic device
US6981983B1 (en) 1999-03-31 2006-01-03 Rosenblatt Peter L System and methods for soft tissue reconstruction
US20050283189A1 (en) * 1999-03-31 2005-12-22 Rosenblatt Peter L Systems and methods for soft tissue reconstruction
US6257241B1 (en) 1999-03-31 2001-07-10 Ethicon Endo-Surgery, Inc. Method for repairing tissue defects using ultrasonic radio frequency energy
US6251110B1 (en) 1999-03-31 2001-06-26 Ethicon Endo-Surgery, Inc. Combined radio frequency and ultrasonic surgical device
WO2000057796A9 (en) * 1999-03-31 2002-07-11 Peter L Rosenblatt Systems and methods for soft tissue reconstruction
US6695859B1 (en) 1999-04-05 2004-02-24 Coalescent Surgical, Inc. Apparatus and methods for anastomosis
US20050222665A1 (en) * 1999-04-23 2005-10-06 Ernest Aranyi Endovascular fastener applicator
US7273497B2 (en) 1999-05-28 2007-09-25 Anova Corp. Methods for treating a defect in the annulus fibrosis
US20060247665A1 (en) 1999-05-28 2006-11-02 Ferree Bret A Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US20070038231A1 (en) 1999-05-28 2007-02-15 Ferree Bret A Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US8617231B2 (en) 2001-05-18 2013-12-31 Boston Scientific Scimed, Inc. Dual guidewire exchange catheter system
US6494888B1 (en) 1999-06-22 2002-12-17 Ndo Surgical, Inc. Tissue reconfiguration
US8287554B2 (en) 1999-06-22 2012-10-16 Ethicon Endo-Surgery, Inc. Method and devices for tissue reconfiguration
US7846180B2 (en) * 1999-06-22 2010-12-07 Ethicon Endo-Surgery, Inc. Tissue fixation devices and methods of fixing tissue
US6835200B2 (en) 1999-06-22 2004-12-28 Ndo Surgical. Inc. Method and devices for tissue reconfiguration
US6821285B2 (en) * 1999-06-22 2004-11-23 Ndo Surgical, Inc. Tissue reconfiguration
US6663639B1 (en) 1999-06-22 2003-12-16 Ndo Surgical, Inc. Methods and devices for tissue reconfiguration
US7955340B2 (en) 1999-06-25 2011-06-07 Usgi Medical, Inc. Apparatus and methods for forming and securing gastrointestinal tissue folds
US7744613B2 (en) 1999-06-25 2010-06-29 Usgi Medical, Inc. Apparatus and methods for forming and securing gastrointestinal tissue folds
US8574243B2 (en) 1999-06-25 2013-11-05 Usgi Medical, Inc. Apparatus and methods for forming and securing gastrointestinal tissue folds
US6626899B2 (en) 1999-06-25 2003-09-30 Nidus Medical, Llc Apparatus and methods for treating tissue
CA2484870A1 (en) * 2002-05-17 2003-11-27 Dvl Acquisition Sub, Inc. Surgical suturing instrument and method of use
US8246671B2 (en) 1999-08-09 2012-08-21 Cardiokinetix, Inc. Retrievable cardiac devices
US9694121B2 (en) 1999-08-09 2017-07-04 Cardiokinetix, Inc. Systems and methods for improving cardiac function
US8529430B2 (en) 2002-08-01 2013-09-10 Cardiokinetix, Inc. Therapeutic methods and devices following myocardial infarction
US7674222B2 (en) 1999-08-09 2010-03-09 Cardiokinetix, Inc. Cardiac device and methods of use thereof
US10064696B2 (en) 2000-08-09 2018-09-04 Edwards Lifesciences Corporation Devices and methods for delivering an endocardial device
US8388672B2 (en) 1999-08-09 2013-03-05 Cardiokinetix, Inc. System for improving cardiac function by sealing a partitioning membrane within a ventricle
US9078660B2 (en) 2000-08-09 2015-07-14 Cardiokinetix, Inc. Devices and methods for delivering an endocardial device
US8257428B2 (en) * 1999-08-09 2012-09-04 Cardiokinetix, Inc. System for improving cardiac function
US7998213B2 (en) 1999-08-18 2011-08-16 Intrinsic Therapeutics, Inc. Intervertebral disc herniation repair
US7717961B2 (en) 1999-08-18 2010-05-18 Intrinsic Therapeutics, Inc. Apparatus delivery in an intervertebral disc
JP4247519B2 (en) 1999-08-18 2009-04-02 イントリンジック セラピューティックス インコーポレイテッド Apparatus and method for the nucleus pulposus augmentation and retention
EP1624832A4 (en) 1999-08-18 2008-12-24 Intrinsic Therapeutics Inc Devices and method for augmenting a vertebral disc nucleus
US6425919B1 (en) 1999-08-18 2002-07-30 Intrinsic Orthopedics, Inc. Devices and methods of vertebral disc augmentation
US7220281B2 (en) 1999-08-18 2007-05-22 Intrinsic Therapeutics, Inc. Implant for reinforcing and annulus fibrosis
US7553329B2 (en) 1999-08-18 2009-06-30 Intrinsic Therapeutics, Inc. Stabilized intervertebral disc barrier
WO2001015605A9 (en) * 1999-08-30 2001-08-09 Applied Med Resources Improved surgical clip
US8529583B1 (en) * 1999-09-03 2013-09-10 Medtronic, Inc. Surgical clip removal apparatus
EP1210014A1 (en) * 1999-09-07 2002-06-05 Microvena Corporation Retrievable septal defect closure device
ES2244402T3 (en) * 1999-09-29 2005-12-16 Zimmer Gmbh Tissue holder.
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6626917B1 (en) 1999-10-26 2003-09-30 H. Randall Craig Helical suture instrument
US6679895B1 (en) * 1999-11-05 2004-01-20 Onux Medical, Inc. Apparatus and method for placing suture wires into tissue for the approximation and tensioning of tissue
US6428548B1 (en) 1999-11-18 2002-08-06 Russell F. Durgin Apparatus and method for compressing body tissue
WO2001043649A9 (en) * 1999-12-17 2002-07-18 Thomas J Fogarty Method and device for use in minimally invasive approximation of muscle and other tissue
US6702732B1 (en) 1999-12-22 2004-03-09 Paracor Surgical, Inc. Expandable cardiac harness for treating congestive heart failure
DE60124872T2 (en) 2000-03-10 2007-06-14 Paracor Medical, Inc., Los Altos Expandable heart bag for treatment of congestive heart failure
US9579091B2 (en) 2000-01-05 2017-02-28 Integrated Vascular Systems, Inc. Closure system and methods of use
US6461364B1 (en) 2000-01-05 2002-10-08 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US8758400B2 (en) 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Closure system and methods of use
US6391048B1 (en) 2000-01-05 2002-05-21 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US6572587B2 (en) 2000-01-10 2003-06-03 Benjamin S. Lerman Anchoring device for medical apparatus
US6551332B1 (en) 2000-03-31 2003-04-22 Coalescent Surgical, Inc. Multiple bias surgical fastener
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
US6468305B1 (en) 2000-05-16 2002-10-22 St. Jude Medical, Inc. Two piece valve
US9332993B2 (en) 2004-08-05 2016-05-10 Cardiokinetix, Inc. Devices and methods for delivering an endocardial device
US9332992B2 (en) 2004-08-05 2016-05-10 Cardiokinetix, Inc. Method for making a laminar ventricular partitioning device
EP1320329A4 (en) * 2000-09-01 2004-09-22 Advanced Vasular Technologies Endovascular fastener and grafting apparatus and method
WO2002017796A1 (en) 2000-09-01 2002-03-07 Advanced Vascular Technologies, Llc Vascular bypass grafting instrument and method
EP1317213A2 (en) * 2000-09-01 2003-06-11 Advanced Vascular Technologies LLC Multi-fastener surgical apparatus and method
EP1294288B1 (en) 2000-09-08 2011-03-30 Abbott Vascular Inc. Surgical staple
US6544265B2 (en) 2000-11-08 2003-04-08 The Cleveland Clinic Foundation Apparatus for implantation into bone related applications
US6468309B1 (en) 2000-10-05 2002-10-22 Cleveland Clinic Foundation Method and apparatus for stabilizing adjacent bones
US6551322B1 (en) 2000-10-05 2003-04-22 The Cleveland Clinic Foundation Apparatus for implantation into bone
US6953462B2 (en) * 2000-10-05 2005-10-11 The Cleveland Clinic Foundation Apparatus for implantation into bone
US6527774B2 (en) 2000-11-08 2003-03-04 The Cleveland Clinic Foundation Apparatus for attaching fractured sections of bone
US6488683B2 (en) 2000-11-08 2002-12-03 Cleveland Clinic Foundation Method and apparatus for correcting spinal deformity
US6551319B2 (en) 2000-11-08 2003-04-22 The Cleveland Clinic Foundation Apparatus for implantation into bone
US6551320B2 (en) 2000-11-08 2003-04-22 The Cleveland Clinic Foundation Method and apparatus for correcting spinal deformity
US6626918B1 (en) 2000-10-06 2003-09-30 Medical Technology Group Apparatus and methods for positioning a vascular sheath
US6926730B1 (en) 2000-10-10 2005-08-09 Medtronic, Inc. Minimally invasive valve repair procedure and apparatus
US6447524B1 (en) 2000-10-19 2002-09-10 Ethicon Endo-Surgery, Inc. Fastener for hernia mesh fixation
US6551333B2 (en) 2000-10-19 2003-04-22 Ethicon Endo-Surgery, Inc. Method for attaching hernia mesh
US6572626B1 (en) 2000-10-19 2003-06-03 Ethicon Endo-Surgery, Inc. Surgical instrument having a fastener delivery mechanism
US6773438B1 (en) 2000-10-19 2004-08-10 Ethicon Endo-Surgery Surgical instrument having a rotary lockout mechanism
US6425900B1 (en) 2000-10-19 2002-07-30 Ethicon Endo-Surgery Method for attaching hernia mesh
US7485124B2 (en) 2000-10-19 2009-02-03 Ethicon Endo-Surgery, Inc. Surgical instrument having a fastener delivery mechanism
US6296607B1 (en) 2000-10-20 2001-10-02 Praxis, Llc. In situ bulking device
JP4139221B2 (en) 2000-10-20 2008-08-27 ディーヴイエル アクイジション エスユービー,インク Surgical suturing instrument and methods of use thereof
US6663633B1 (en) * 2000-10-25 2003-12-16 Pierson, Iii Raymond H. Helical orthopedic fixation and reduction device, insertion system, and associated methods
US7033373B2 (en) 2000-11-03 2006-04-25 Satiety, Inc. Method and device for use in minimally invasive placement of space-occupying intragastric devices
US20020128670A1 (en) * 2000-11-22 2002-09-12 Ulf Ulmsten Surgical instrument and method for treating female urinary incontinence
FR2817185B1 (en) * 2000-11-28 2003-01-24 Satelec Soc Cle dynamometric
US6623510B2 (en) 2000-12-07 2003-09-23 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US8690910B2 (en) 2000-12-07 2014-04-08 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7211101B2 (en) 2000-12-07 2007-05-01 Abbott Vascular Devices Methods for manufacturing a clip and clip
WO2002061217A1 (en) * 2001-02-01 2002-08-08 Rockwool International A/S A method of joining two or more units of insulating material
US20020161382A1 (en) * 2001-03-29 2002-10-31 Neisz Johann J. Implant inserted without bone anchors
US7144413B2 (en) 2001-04-20 2006-12-05 Synthes (U.S.A.) Graft fixation system and method
US7083629B2 (en) * 2001-05-30 2006-08-01 Satiety, Inc. Overtube apparatus for insertion into a body
US6558400B2 (en) 2001-05-30 2003-05-06 Satiety, Inc. Obesity treatment tools and methods
US6902570B2 (en) 2001-06-08 2005-06-07 Rolf Dieter Schraft Device and method for connecting hollow organs and/or sealing wall defects in hollow organs
DE10147632B4 (en) * 2001-06-08 2005-10-20 Fraunhofer Ges Forschung Device for connecting hollow organs, and / or sealing wall defects of hollow organs
US6986776B2 (en) * 2001-06-28 2006-01-17 Craig H Randall Suturing apparatus, method and system
US7288105B2 (en) * 2001-08-01 2007-10-30 Ev3 Endovascular, Inc. Tissue opening occluder
DE60215819T2 (en) * 2001-08-03 2007-09-06 Tyco Healthcare Group Lp, Norwalk Marker tissue marking device for use with a
EP2305342A3 (en) * 2001-08-22 2013-04-03 Gore Enterprise Holdings, Inc. Apparatus and methods for treating strokes and controlling cerebral flow characteristics
US7101395B2 (en) * 2002-06-12 2006-09-05 Mitral Interventions, Inc. Method and apparatus for tissue connection
US20060052821A1 (en) 2001-09-06 2006-03-09 Ovalis, Inc. Systems and methods for treating septal defects
US6776784B2 (en) 2001-09-06 2004-08-17 Core Medical, Inc. Clip apparatus for closing septal defects and methods of use
US8579936B2 (en) 2005-07-05 2013-11-12 ProMed, Inc. Centering of delivery devices with respect to a septal defect
US6702835B2 (en) 2001-09-07 2004-03-09 Core Medical, Inc. Needle apparatus for closing septal defects and methods for using such apparatus
US6723041B2 (en) 2001-09-10 2004-04-20 Lilip Lau Device for treating heart failure
EP1435822A4 (en) * 2001-09-14 2009-09-09 Dvl Acquisition Sub Inc Surgical suturing instrument and method of use
JP2005525862A (en) * 2002-05-17 2005-09-02 オーナックス・メディカル・インコーポレーテッド Surgical suturing instrument and methods of use thereof
RU2194274C1 (en) * 2001-09-18 2002-12-10 ЗАО "Нефтегазкомплектсервис" Technology of intratube ultrasonic flaw detection
JP2005507706A (en) 2001-10-31 2005-03-24 パラコー メディカル インコーポレイテッド Heart failure therapy device
US20050177180A1 (en) * 2001-11-28 2005-08-11 Aptus Endosystems, Inc. Devices, systems, and methods for supporting tissue and/or structures within a hollow body organ
US8075570B2 (en) * 2001-11-28 2011-12-13 Aptus Endosystems, Inc. Intraluminal prosthesis attachment systems and methods
US20070073389A1 (en) 2001-11-28 2007-03-29 Aptus Endosystems, Inc. Endovascular aneurysm devices, systems, and methods
EP1448117B1 (en) * 2001-11-28 2013-05-22 Aptus Endosystems, Inc. Endovascular aneurysm repair system
CN101466316B (en) 2005-10-20 2012-06-27 阿普特斯内系统公司 Devices systems and methods for prosthesis delivery and implantation including the use of a fastener tool
US8231639B2 (en) 2001-11-28 2012-07-31 Aptus Endosystems, Inc. Systems and methods for attaching a prosthesis within a body lumen or hollow organ
US20050070992A1 (en) 2001-11-28 2005-03-31 Aptus Endosystems, Inc. Prosthesis systems and methods sized and configured for the receipt and retention of fasteners
GB2417208B (en) * 2001-11-28 2006-06-28 Aptus Endosystems Inc Intraluminal prosthesis attachment systems
US7022063B2 (en) 2002-01-07 2006-04-04 Paracor Medical, Inc. Cardiac harness
US6869436B2 (en) * 2002-02-07 2005-03-22 Scimed Life Systems, Inc. Surgical clip with a self-releasing fluid reservoir
US6749621B2 (en) 2002-02-21 2004-06-15 Integrated Vascular Systems, Inc. Sheath apparatus and methods for delivering a closure device
US7357773B2 (en) 2002-03-07 2008-04-15 Ams Research Corporation Handle and surgical article
US6911003B2 (en) 2002-03-07 2005-06-28 Ams Research Corporation Transobturator surgical articles and methods
US7070556B2 (en) * 2002-03-07 2006-07-04 Ams Research Corporation Transobturator surgical articles and methods
CA2479974A1 (en) * 2002-03-25 2003-10-09 Dvl Acquisition Sub, Inc. Surgical suturing instrument and method of use
US7007698B2 (en) * 2002-04-03 2006-03-07 Boston Scientific Corporation Body lumen closure
US7335221B2 (en) * 2002-04-12 2008-02-26 Ethicon, Inc. Suture anchoring and tensioning device and method for using same
DE60336123D1 (en) * 2002-04-17 2011-04-07 Tyco Healthcare stapling instrument
US20030199974A1 (en) * 2002-04-18 2003-10-23 Coalescent Surgical, Inc. Annuloplasty apparatus and methods
WO2003088846A1 (en) * 2002-04-22 2003-10-30 Tyco Healthcare Group, Lp Tack and tack applier
US8241308B2 (en) 2002-04-24 2012-08-14 Boston Scientific Scimed, Inc. Tissue fastening devices and processes that promote tissue adhesion
US7316693B2 (en) * 2002-04-29 2008-01-08 Tyco Healthcare Group Lp Ligation clip applier and method
US7077850B2 (en) * 2002-05-01 2006-07-18 Scimed Life Systems, Inc. Tissue fastening devices and related insertion tools and methods
US6773440B2 (en) 2002-07-02 2004-08-10 Satiety, Inc. Method and device for use in tissue approximation and fixation
US7255710B2 (en) * 2002-08-06 2007-08-14 Icon Medical Corp. Helical stent with micro-latches
US6746460B2 (en) 2002-08-07 2004-06-08 Satiety, Inc. Intra-gastric fastening devices
US7214233B2 (en) 2002-08-30 2007-05-08 Satiety, Inc. Methods and devices for maintaining a space occupying device in a relatively fixed location within a stomach
US7033384B2 (en) 2002-08-30 2006-04-25 Satiety, Inc. Stented anchoring of gastric space-occupying devices
EP1534173A2 (en) 2002-09-05 2005-06-01 Paracor Medical, Inc. Cardiac harness
US8066724B2 (en) 2002-09-12 2011-11-29 Medtronic, Inc. Anastomosis apparatus and methods
US6966919B2 (en) 2002-09-20 2005-11-22 Id, Llc Instrument for applying a surgical fastener particularly for the transoral treatment of gastroesophageal reflux disease (GERD)
US7678122B2 (en) * 2002-09-20 2010-03-16 Id, Llc Method of performing a treatment for gastroesophagheal reflux disease (GERD)
US8454628B2 (en) * 2002-09-20 2013-06-04 Syntheon, Llc Surgical fastener aligning instrument particularly for transoral treatment of gastroesophageal reflux disease
US7033378B2 (en) * 2002-09-20 2006-04-25 Id, Llc Surgical fastener, particularly for the endoluminal treatment of gastroesophageal reflux disease (GERD)
US8105345B2 (en) 2002-10-04 2012-01-31 Medtronic, Inc. Anastomosis apparatus and methods
US20040073237A1 (en) * 2002-10-08 2004-04-15 Leinsing Karl R. Surgical fastener and delivery system
US7087064B1 (en) 2002-10-15 2006-08-08 Advanced Cardiovascular Systems, Inc. Apparatuses and methods for heart valve repair
US7220237B2 (en) 2002-10-23 2007-05-22 Satiety, Inc. Method and device for use in endoscopic organ procedures
EP1750595A4 (en) 2004-05-07 2008-10-22 Valentx Inc Devices and methods for attaching an endolumenal gastrointestinal implant
US7837669B2 (en) 2002-11-01 2010-11-23 Valentx, Inc. Devices and methods for endolumenal gastrointestinal bypass
US9060844B2 (en) 2002-11-01 2015-06-23 Valentx, Inc. Apparatus and methods for treatment of morbid obesity
US7794447B2 (en) 2002-11-01 2010-09-14 Valentx, Inc. Gastrointestinal sleeve device and methods for treatment of morbid obesity
EP1560541A2 (en) 2002-11-15 2005-08-10 Paracor Medical, Inc. Cardiac harness delivery device
US7331972B1 (en) 2002-11-15 2008-02-19 Abbott Cardiovascular Systems Inc. Heart valve chord cutter
US7404824B1 (en) 2002-11-15 2008-07-29 Advanced Cardiovascular Systems, Inc. Valve aptation assist device
US7736299B2 (en) 2002-11-15 2010-06-15 Paracor Medical, Inc. Introducer for a cardiac harness delivery
US7485143B2 (en) 2002-11-15 2009-02-03 Abbott Cardiovascular Systems Inc. Apparatuses and methods for heart valve repair
US7229405B2 (en) 2002-11-15 2007-06-12 Paracor Medical, Inc. Cardiac harness delivery device and method of use
US7335213B1 (en) 2002-11-15 2008-02-26 Abbott Cardiovascular Systems Inc. Apparatus and methods for heart valve repair
US8187324B2 (en) 2002-11-15 2012-05-29 Advanced Cardiovascular Systems, Inc. Telescoping apparatus for delivering and adjusting a medical device in a vessel
US6945978B1 (en) 2002-11-15 2005-09-20 Advanced Cardiovascular Systems, Inc. Heart valve catheter
US7942898B2 (en) 2002-12-11 2011-05-17 Usgi Medical, Inc. Delivery systems and methods for gastric reduction
US7416554B2 (en) 2002-12-11 2008-08-26 Usgi Medical Inc Apparatus and methods for forming and securing gastrointestinal tissue folds
US7942884B2 (en) 2002-12-11 2011-05-17 Usgi Medical, Inc. Methods for reduction of a gastric lumen
US7618426B2 (en) 2002-12-11 2009-11-17 Usgi Medical, Inc. Apparatus and methods for forming gastrointestinal tissue approximations
US6893025B2 (en) * 2002-12-19 2005-05-17 Henry C. Hight, Jr. Gaskets and gasket-like devices including fasteners for gaskets and a method of making and using the same
US7758638B2 (en) * 2004-07-13 2010-07-20 Ats Medical, Inc. Implant with an annular base
US7637905B2 (en) 2003-01-15 2009-12-29 Usgi Medical, Inc. Endoluminal tool deployment system
US8202293B2 (en) 2003-01-30 2012-06-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US7905900B2 (en) 2003-01-30 2011-03-15 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8398656B2 (en) 2003-01-30 2013-03-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
EP1596723A2 (en) 2003-02-04 2005-11-23 ev3 Sunnyvale, Inc. Patent foramen ovale closure system
US8900253B2 (en) 2003-03-11 2014-12-02 Covidien Lp Clip applying apparatus with angled jaw
US7175638B2 (en) 2003-04-16 2007-02-13 Satiety, Inc. Method and devices for modifying the function of a body organ
US8246974B2 (en) 2003-05-02 2012-08-21 Surmodics, Inc. Medical devices and methods for producing the same
WO2004098565A3 (en) 2003-05-02 2005-03-03 Aron B Anderson Implantable controlled release bioactive agent delivery device
US8926637B2 (en) 2003-06-13 2015-01-06 Covidien Lp Multiple member interconnect for surgical instrument and absorbable screw fastener
EP1635723B1 (en) 2003-06-13 2011-08-10 Tyco Healthcare Group LP Multiple member interconnect for surgical instrument and absorbable screw fastener
US7374557B2 (en) 2003-06-16 2008-05-20 Ethicon Endo-Surgery, Inc. Subcutaneous self attaching injection port with integral fasteners
US8715243B2 (en) 2003-06-16 2014-05-06 Ethicon Endo-Surgery, Inc. Injection port applier with downward force actuation
US8029477B2 (en) 2003-12-19 2011-10-04 Ethicon Endo-Surgery, Inc. Applier with safety for implantable medical device
US7862546B2 (en) 2003-06-16 2011-01-04 Ethicon Endo-Surgery, Inc. Subcutaneous self attaching injection port with integral moveable retention members
US8162897B2 (en) 2003-12-19 2012-04-24 Ethicon Endo-Surgery, Inc. Audible and tactile feedback
EP1638485B1 (en) 2003-06-20 2011-03-02 Intrinsic Therapeutics, Inc. Device for delivering an implant through an annular defect in an intervertebral disc
FR2856581B1 (en) * 2003-06-27 2005-08-19 Medicrea of vertebral osteosynthesis material
US8308772B2 (en) * 2003-06-27 2012-11-13 Medicrea Technologies Vertebral osteosynthesis equipment
US8047890B1 (en) 2004-02-05 2011-11-01 James Haas Toy construction set and method
US20050002753A1 (en) * 2003-07-03 2005-01-06 Haas James R. Rotary fastener, fastenable material, fastener system, and storage system
US8142128B1 (en) 2004-02-05 2012-03-27 James Haas Anchor and method for anchoring
US8230794B1 (en) 2004-02-05 2012-07-31 James Haas Holding system and method for a workbench
EP1648333A2 (en) 2003-07-10 2006-04-26 Paracor Medical, Inc. Self-anchoring cardiac harness
JP2007518446A (en) * 2003-07-11 2007-07-12 エンドグン・メディカル・システムズ・リミテッド Surgical fasteners and surgical fastening device
US7655030B2 (en) 2003-07-18 2010-02-02 Boston Scientific Scimed, Inc. Catheter balloon systems and methods
US7182769B2 (en) 2003-07-25 2007-02-27 Medtronic, Inc. Sealing clip, delivery systems, and methods
US20050043749A1 (en) 2003-08-22 2005-02-24 Coalescent Surgical, Inc. Eversion apparatus and methods
US7371244B2 (en) * 2003-08-25 2008-05-13 Ethicon, Inc. Deployment apparatus for suture anchoring device
US7347812B2 (en) 2003-09-22 2008-03-25 Ams Research Corporation Prolapse repair
US8394114B2 (en) 2003-09-26 2013-03-12 Medtronic, Inc. Surgical connection apparatus and methods
US7998112B2 (en) 2003-09-30 2011-08-16 Abbott Cardiovascular Systems Inc. Deflectable catheter assembly and method of making same
US7914543B2 (en) 2003-10-14 2011-03-29 Satiety, Inc. Single fold device for tissue fixation
US7097650B2 (en) 2003-10-14 2006-08-29 Satiety, Inc. System for tissue approximation and fixation
US7147657B2 (en) 2003-10-23 2006-12-12 Aptus Endosystems, Inc. Prosthesis delivery systems and methods
EP2213244A1 (en) * 2003-10-24 2010-08-04 ev3 Endovascular, Inc. Patent foramen ovale closure system
US7158839B2 (en) 2003-11-07 2007-01-02 Paracor Medical, Inc. Cardiac harness for treating heart disease
US7155295B2 (en) 2003-11-07 2006-12-26 Paracor Medical, Inc. Cardiac harness for treating congestive heart failure and for defibrillating and/or pacing/sensing
US7879047B2 (en) 2003-12-10 2011-02-01 Medtronic, Inc. Surgical connection apparatus and methods
EP1547526A1 (en) * 2003-12-23 2005-06-29 UMC Utrecht Holding B.V. Operation element, operation set and method for use thereof
US7618427B2 (en) * 2003-12-29 2009-11-17 Ethicon Endo-Surgery, Inc. Device and method for intralumenal anastomosis
US7273469B1 (en) 2003-12-31 2007-09-25 Advanced Cardiovascular Systems, Inc. Modified needle catheter for directional orientation delivery
CA2553185A1 (en) 2004-01-12 2005-08-04 Paracor Medical, Inc. Cardiac harness having interconnected strands
US20050177176A1 (en) 2004-02-05 2005-08-11 Craig Gerbi Single-fold system for tissue approximation and fixation
EP1714409A1 (en) * 2004-02-12 2006-10-25 Northrop Grumman Corporation Photonic rf distribution system
EP1713402B1 (en) 2004-02-13 2018-07-04 Ethicon Endo-Surgery, Inc. Device for reducing stomach volume
US20050187568A1 (en) * 2004-02-20 2005-08-25 Klenk Alan R. Devices and methods for closing a patent foramen ovale with a coil-shaped closure device
US20050187565A1 (en) 2004-02-20 2005-08-25 Baker Steve G. Tissue fixation devices and a transoral endoscopic gastroesophageal flap valve restoration device and assembly using same
US7632287B2 (en) 2004-02-20 2009-12-15 Endogastric Solutions, Inc. Tissue fixation devices and assemblies for deploying the same
WO2005084592A2 (en) 2004-02-27 2005-09-15 Satiety, Inc. Methods and devices for reducing hollow organ volume
US7762943B2 (en) 2004-03-03 2010-07-27 Cardiokinetix, Inc. Inflatable ventricular partitioning device
US7976539B2 (en) 2004-03-05 2011-07-12 Hansen Medical, Inc. System and method for denaturing and fixing collagenous tissue
US8252009B2 (en) 2004-03-09 2012-08-28 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US8628547B2 (en) 2004-03-09 2014-01-14 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
US8449560B2 (en) 2004-03-09 2013-05-28 Satiety, Inc. Devices and methods for placement of partitions within a hollow body organ
US7703459B2 (en) 2004-03-09 2010-04-27 Usgi Medical, Inc. Apparatus and methods for mapping out endoluminal gastrointestinal surgery
US9028511B2 (en) 2004-03-09 2015-05-12 Ethicon Endo-Surgery, Inc. Devices and methods for placement of partitions within a hollow body organ
EP1750627B1 (en) 2004-03-26 2018-10-10 Ethicon Endo-Surgery, Inc. System for reducing stomach volume
US20160213411A9 (en) * 2004-04-27 2016-07-28 John Isbell Shipp Absorbable Fastener for Hernia Mesh Fixation
US7500945B2 (en) 2004-04-30 2009-03-10 Ams Research Corporation Method and apparatus for treating pelvic organ prolapse
US7811222B2 (en) 2004-04-30 2010-10-12 Ams Research Corporation Method and apparatus for treating pelvic organ prolapse
US7736374B2 (en) 2004-05-07 2010-06-15 Usgi Medical, Inc. Tissue manipulation and securement system
US7347863B2 (en) 2004-05-07 2008-03-25 Usgi Medical, Inc. Apparatus and methods for manipulating and securing tissue
US8308765B2 (en) 2004-05-07 2012-11-13 Usgi Medical, Inc. Apparatus and methods for positioning and securing anchors
US7351197B2 (en) 2004-05-07 2008-04-01 Ams Research Corporation Method and apparatus for cystocele repair
US8057511B2 (en) 2004-05-07 2011-11-15 Usgi Medical, Inc. Apparatus and methods for positioning and securing anchors
US8444657B2 (en) 2004-05-07 2013-05-21 Usgi Medical, Inc. Apparatus and methods for rapid deployment of tissue anchors
US7621925B2 (en) 2004-05-07 2009-11-24 Usgi Medical, Inc. Needle assembly for tissue manipulation
US7361180B2 (en) 2004-05-07 2008-04-22 Usgi Medical, Inc. Apparatus for manipulating and securing tissue
US7918869B2 (en) 2004-05-07 2011-04-05 Usgi Medical, Inc. Methods and apparatus for performing endoluminal gastroplasty
US8257394B2 (en) 2004-05-07 2012-09-04 Usgi Medical, Inc. Apparatus and methods for positioning and securing anchors
US8216252B2 (en) 2004-05-07 2012-07-10 Usgi Medical, Inc. Tissue manipulation and securement system
FR2870111B1 (en) * 2004-05-13 2007-03-02 Microval Sarl Element immobilizing a mesh acting prosthesis
US7695493B2 (en) 2004-06-09 2010-04-13 Usgi Medical, Inc. System for optimizing anchoring force
US8206417B2 (en) 2004-06-09 2012-06-26 Usgi Medical Inc. Apparatus and methods for optimizing anchoring force
US7736379B2 (en) 2004-06-09 2010-06-15 Usgi Medical, Inc. Compressible tissue anchor assemblies
US7678135B2 (en) 2004-06-09 2010-03-16 Usgi Medical, Inc. Compressible tissue anchor assemblies
WO2006002366A3 (en) * 2004-06-24 2006-03-16 Aron B Anderson Biodegradable ocular devices, methods and systems
US20050288689A1 (en) * 2004-06-25 2005-12-29 Kammerer Gene W Applicator and method for deploying a surgical fastener
US7678133B2 (en) * 2004-07-10 2010-03-16 Arstasis, Inc. Biological tissue closure device and method
EP1778077B1 (en) * 2004-07-23 2015-01-14 Varian Medical Systems, Inc. Wireless markers for anchoring within a human body
US9138228B2 (en) 2004-08-11 2015-09-22 Emory University Vascular conduit device and system for implanting
WO2006023130A3 (en) * 2004-08-12 2006-08-03 Aron B Anderson Biodegradable controlled release bioactive agent delivery device
DE602005010442D1 (en) * 2004-08-16 2008-11-27 Zimmer Spine Inc Spiral sewing device
US7452368B2 (en) * 2004-09-15 2008-11-18 Ethicon, Inc. System for holding surgical fasteners
DE102004047974A1 (en) * 2004-10-01 2006-04-06 Ethicon Gmbh surgical hook
WO2006042084A3 (en) 2004-10-08 2009-04-16 Tyco Healthcare Endoscopic surgical clip applier
US9763668B2 (en) 2004-10-08 2017-09-19 Covidien Lp Endoscopic surgical clip applier
WO2006042110A3 (en) 2004-10-08 2009-04-09 Tyco Healthcare Apparatus for applying surgical clips
US20080195096A1 (en) * 2004-10-15 2008-08-14 The University Of British Columbia Orthopaedic Helical Coil Fastener and Apparatus and Method for Implantation Thereof
US20080125869A1 (en) * 2004-11-08 2008-05-29 Adrian Paz Surgical Grafts
US20060106405A1 (en) * 2004-11-16 2006-05-18 Fann James I Systems and methods for delivering fastener to opposed tissue structures
US20060106288A1 (en) 2004-11-17 2006-05-18 Roth Alex T Remote tissue retraction device
DE202004017974U1 (en) * 2004-11-19 2005-01-13 Jörg Wenzler Medizintechnik GmbH A surgical cutting instrument
US20060116697A1 (en) 2004-11-30 2006-06-01 Esophyx, Inc. Flexible transoral endoscopic gastroesophageal flap valve restoration device and method
US20060129152A1 (en) * 2004-12-10 2006-06-15 Shipp John I Absorbable Anchor for Hernia Mesh Fixation
US7981152B1 (en) 2004-12-10 2011-07-19 Advanced Cardiovascular Systems, Inc. Vascular delivery system for accessing and delivering devices into coronary sinus and other vascular sites
US20060167481A1 (en) 2005-01-25 2006-07-27 Esophyx, Inc. Slitted tissue fixation devices and assemblies for deploying the same
EP1848344A4 (en) * 2005-02-04 2014-01-29 Moshe Dudai Staples, staplers, anastomosis devices, and methods for their applications
US20060184201A1 (en) * 2005-02-17 2006-08-17 James Jervis E Suture retainer with suture guide and method of using a suture retainer with a suture guide
US8021374B2 (en) * 2005-03-08 2011-09-20 The Trustees Of Stevens Institute Of Technology Method and device for the controlled delivery and placement of securing elements in a body
WO2006097931A3 (en) 2005-03-17 2007-07-26 Valtech Cardio Ltd Mitral valve treatment techniques
US20100189764A1 (en) * 2005-03-22 2010-07-29 Jonathan Thomas Bioactive mesh
EP1861055A4 (en) * 2005-03-22 2013-01-16 Covidien Lp Bioactive wide-weave mesh
US9149602B2 (en) 2005-04-22 2015-10-06 Advanced Cardiovascular Systems, Inc. Dual needle delivery system
US20060253127A1 (en) * 2005-05-04 2006-11-09 Bernard Medical, Llc Endoluminal linear suturing device
CN101198301A (en) * 2005-05-18 2008-06-11 苏尔莫迪克斯公司 Insertion instrument for non-linear medical devices
US9585651B2 (en) 2005-05-26 2017-03-07 Usgi Medical, Inc. Methods and apparatus for securing and deploying tissue anchors
US8298291B2 (en) 2005-05-26 2012-10-30 Usgi Medical, Inc. Methods and apparatus for securing and deploying tissue anchors
US8092528B2 (en) 2005-05-27 2012-01-10 Depuy Spine, Inc. Intervertebral ligament having a helical bone fastener
US7722610B2 (en) * 2005-06-02 2010-05-25 Tyco Healthcare Group Lp Multiple coil staple and staple applier
US20060291981A1 (en) * 2005-06-02 2006-12-28 Viola Frank J Expandable backspan staple
US8398537B2 (en) 2005-06-10 2013-03-19 Cardiokinetix, Inc. Peripheral seal for a ventricular partitioning device
US7918844B2 (en) 2005-06-24 2011-04-05 Ethicon Endo-Surgery, Inc. Applier for implantable medical device
US7651483B2 (en) 2005-06-24 2010-01-26 Ethicon Endo-Surgery, Inc. Injection port
US8926633B2 (en) 2005-06-24 2015-01-06 Abbott Laboratories Apparatus and method for delivering a closure element
US7561916B2 (en) 2005-06-24 2009-07-14 Ethicon Endo-Surgery, Inc. Implantable medical device with indicator
US8313497B2 (en) 2005-07-01 2012-11-20 Abbott Laboratories Clip applier and methods of use
US9241710B2 (en) * 2005-07-06 2016-01-26 I.B.I Israel Biomedical Innovations Ltd. Surgical fasteners and fastening devices
US7587247B2 (en) 2005-08-01 2009-09-08 Paracor Medical, Inc. Cardiac harness having an optimal impedance range
WO2007017562A1 (en) * 2005-08-04 2007-02-15 Microval Element for blocking the movement of a mesh structure serving as a prosthesis
US8252006B2 (en) * 2005-08-05 2012-08-28 Ethicon Endo-Surgery, Inc. Single pass gastric restriction with a corkscrew style wall anchor
US20070038232A1 (en) 2005-08-12 2007-02-15 Kraemer Stefan J M Apparatus and method for securing the stomach to the diaphragm for use, for example, in treating hiatal hernias and gastroesophageal reflux disease
US9492277B2 (en) * 2005-08-30 2016-11-15 Mayo Foundation For Medical Education And Research Soft body tissue remodeling methods and apparatus
US7846179B2 (en) 2005-09-01 2010-12-07 Ovalis, Inc. Suture-based systems and methods for treating septal defects
US20070083235A1 (en) * 2005-10-11 2007-04-12 Jervis James E Helical retainer, tool for using the helical retainer, and methods
US20070088373A1 (en) 2005-10-18 2007-04-19 Endogastric Solutions, Inc. Invaginator for gastroesophageal flap valve restoration device
ES2470338T3 (en) 2005-11-14 2014-06-23 C.R. Bard, Inc. Anchor System sling
US7815659B2 (en) 2005-11-15 2010-10-19 Ethicon Endo-Surgery, Inc. Suture anchor applicator
US20070118151A1 (en) * 2005-11-21 2007-05-24 The Brigham And Women's Hospital, Inc. Percutaneous cardiac valve repair with adjustable artificial chordae
US7632308B2 (en) 2005-11-23 2009-12-15 Didier Loulmet Methods, devices, and kits for treating mitral valve prolapse
WO2007061417A3 (en) * 2005-11-23 2009-04-16 Arthrex Inc Handle system for suture driving device
US20070129755A1 (en) * 2005-12-05 2007-06-07 Ovalis, Inc. Clip-based systems and methods for treating septal defects
US7972337B2 (en) 2005-12-28 2011-07-05 Intrinsic Therapeutics, Inc. Devices and methods for bone anchoring
US8726909B2 (en) 2006-01-27 2014-05-20 Usgi Medical, Inc. Methods and apparatus for revision of obesity procedures
US8821561B2 (en) 2006-02-22 2014-09-02 Boston Scientific Scimed, Inc. Marker arrangement for bifurcation catheter
US7815652B2 (en) * 2006-03-21 2010-10-19 Ethicon Endo-Surgery, Inc. Surgical fastener and instrument
US20070244556A1 (en) * 2006-04-12 2007-10-18 Medtronic Vascular, Inc. Annuloplasty Device Having a Helical Anchor and Methods for its Use
US20070244555A1 (en) * 2006-04-12 2007-10-18 Medtronic Vascular, Inc. Annuloplasty Device Having a Helical Anchor and Methods for its Use
US7699892B2 (en) 2006-04-12 2010-04-20 Medtronic Vascular, Inc. Minimally invasive procedure for implanting an annuloplasty device
US8808310B2 (en) 2006-04-20 2014-08-19 Integrated Vascular Systems, Inc. Resettable clip applier and reset tools
US7881797B2 (en) 2006-04-25 2011-02-01 Valentx, Inc. Methods and devices for gastrointestinal stimulation
US8764835B2 (en) 2006-06-13 2014-07-01 Bret A. Ferree Intervertebral disc treatment methods and apparatus
US8834496B2 (en) 2006-06-13 2014-09-16 Bret A. Ferree Soft tissue repair methods and apparatus
US9232938B2 (en) 2006-06-13 2016-01-12 Anova Corp. Method and apparatus for closing fissures in the annulus fibrosus
US8556930B2 (en) * 2006-06-28 2013-10-15 Abbott Laboratories Vessel closure device
US8870916B2 (en) 2006-07-07 2014-10-28 USGI Medical, Inc Low profile tissue anchors, tissue anchor systems, and methods for their delivery and use
US8672829B2 (en) * 2006-07-10 2014-03-18 Ams Research Corporation Methods and articles for treatment of rectal prolapse
USD545903S1 (en) * 2006-07-10 2007-07-03 Mark Ross Paper tack
US8348973B2 (en) * 2006-09-06 2013-01-08 Covidien Lp Bioactive substance in a barbed suture
ES2329092T3 (en) 2006-09-06 2009-11-20 Tyco Healthcare Group, Lp Barbed sutures.
US8758398B2 (en) 2006-09-08 2014-06-24 Integrated Vascular Systems, Inc. Apparatus and method for delivering a closure element
US8480559B2 (en) 2006-09-13 2013-07-09 C. R. Bard, Inc. Urethral support system
EP2068768A4 (en) * 2006-09-25 2014-01-08 Corassist Cardiovascular Ltd Method and system for improving diastolic function of the heart
US8623049B2 (en) * 2006-09-28 2014-01-07 Tendon Technology, Ltd. Soft tissue anchor and methods and apparatus for securing soft tissue
US9017345B2 (en) * 2006-10-06 2015-04-28 Covidien Lp Coil fastener applier with flexible shaft
CA2605135C (en) 2006-10-17 2014-12-30 Tyco Healthcare Group Lp Apparatus for applying surgical clips
US8246533B2 (en) 2006-10-20 2012-08-21 Ellipse Technologies, Inc. Implant system with resonant-driven actuator
US7862502B2 (en) 2006-10-20 2011-01-04 Ellipse Technologies, Inc. Method and apparatus for adjusting a gastrointestinal restriction device
US20080140203A1 (en) * 2006-10-24 2008-06-12 Reginald Davis Intervertebral disc support coil and screw applicator
US8353931B2 (en) * 2006-11-02 2013-01-15 Covidien Lp Long term bioabsorbable barbed sutures
US9974653B2 (en) 2006-12-05 2018-05-22 Valtech Cardio, Ltd. Implantation of repair devices in the heart
WO2008085994A3 (en) 2007-01-08 2008-09-18 Endogastric Solutions Connected fasteners, delivery device and method
US20110178466A1 (en) * 2007-01-26 2011-07-21 Ingenium Medical Solutions Limited Medical attachment device
JP2008192187A (en) * 2007-01-31 2008-08-21 Fujitsu Ltd Head controller, memory device, and contact detection method
WO2008097586A3 (en) * 2007-02-06 2008-12-24 Univ Ohio State Res Found Endolumenal restriction method and apparatus
US20100323961A1 (en) * 2007-02-09 2010-12-23 Tyco Healthcare Group Lp Surface eroding sutures
US20080195147A1 (en) * 2007-02-09 2008-08-14 Tyco Healthcare Group Lp Surface eroding barbed sutures
KR100821215B1 (en) * 2007-02-14 2008-04-11 주식회사 동양플렉스 Protection device for head of roof sprinkler
US20080200377A1 (en) * 2007-02-16 2008-08-21 Trollsas Mikael O Polymer particles
US20080208214A1 (en) * 2007-02-26 2008-08-28 Olympus Medical Systems Corp. Applicator and tissue fastening method through natural orifice
US8852216B2 (en) 2007-03-23 2014-10-07 Ethicon Endo-Surgery, Inc. Tissue approximation methods
US7951159B2 (en) 2007-04-04 2011-05-31 Ethicon Endo-Surgery, Inc. Method for plicating and fastening gastric tissue
US7722628B2 (en) * 2007-04-04 2010-05-25 Ethicon Endo-Surgery, Inc. Device for plicating and fastening gastric tissue
US7803165B2 (en) 2007-04-04 2010-09-28 Ethicon Endo-Surgery, Inc. Device for plicating and fastening gastric tissue
US7803166B2 (en) 2007-04-04 2010-09-28 Ethicon Endo-Surgery, Inc. Method for plicating and fastening gastric tissue
US7799040B2 (en) 2007-04-04 2010-09-21 Ethicon Endo-Surgery, Inc. Device for plicating and fastening gastric tissue
US7815653B2 (en) 2007-04-04 2010-10-19 Ethicon Endo-Surgery, Inc. Method for plicating and fastening gastric tissue
CN102327136B (en) 2007-04-11 2014-04-23 柯惠Lp公司 Surgical clip applier
US7846123B2 (en) 2007-04-24 2010-12-07 Emory University Conduit device and system for implanting a conduit device in a tissue wall
US20090036923A1 (en) * 2007-05-04 2009-02-05 Jabba Ronald J Systems and methods for accommodating anatomical characteristics in the treatment of septal defects
US20080277445A1 (en) * 2007-05-07 2008-11-13 Zergiebel Earl M Single fire tacker instrument
US7931660B2 (en) * 2007-05-10 2011-04-26 Tyco Healthcare Group Lp Powered tacker instrument
WO2008154450A1 (en) 2007-06-08 2008-12-18 Valentx, Inc. Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices
WO2009011824A1 (en) * 2007-07-13 2009-01-22 The Brigham And Women's Hospital, Inc. System and method for hernia mesh fixation
DE102007034577A1 (en) * 2007-07-13 2009-01-15 Karl Storz Gmbh & Co. Kg medical instrument
EP2175795A4 (en) * 2007-07-20 2014-12-24 Calypso Med Technologies Inc Implantable devices and methods for external beam radiation treatments
US8486134B2 (en) 2007-08-01 2013-07-16 Boston Scientific Scimed, Inc. Bifurcation treatment system and methods
US8192351B2 (en) 2007-08-13 2012-06-05 Paracor Medical, Inc. Medical device delivery system having integrated introducer
US20100241161A1 (en) * 2007-08-16 2010-09-23 I.B.I Israel Biomedical Innovations Ltd. Surgical fasteners and devices for surgical fastening
US8323341B2 (en) 2007-09-07 2012-12-04 Intrinsic Therapeutics, Inc. Impaction grafting for vertebral fusion
US20110196492A1 (en) 2007-09-07 2011-08-11 Intrinsic Therapeutics, Inc. Bone anchoring systems
US20090105815A1 (en) * 2007-10-19 2009-04-23 Matthew Krever Push-in retainer system for use in the direct plication annuloplasty treatment of mitral valve regurgitation
US8197464B2 (en) * 2007-10-19 2012-06-12 Cordis Corporation Deflecting guide catheter for use in a minimally invasive medical procedure for the treatment of mitral valve regurgitation
US20090112236A1 (en) * 2007-10-29 2009-04-30 Tyco Healthcare Group Lp Filament-Reinforced Composite Fiber
US8206280B2 (en) 2007-11-13 2012-06-26 C. R. Bard, Inc. Adjustable tissue support member
FR2924917B1 (en) * 2007-12-13 2011-02-11 Microval laying apparatus suture resulting turns of a metallic wire has shape memory.
US8893947B2 (en) 2007-12-17 2014-11-25 Abbott Laboratories Clip applier and methods of use
US20090157101A1 (en) 2007-12-17 2009-06-18 Abbott Laboratories Tissue closure system and methods of use
US7841502B2 (en) 2007-12-18 2010-11-30 Abbott Laboratories Modular clip applier
US8597336B2 (en) * 2007-12-28 2013-12-03 Howmedica Osteonics Corp. Apparatus for discrete tissue anchoring for soft tissue repair and method of use
WO2009088953A3 (en) 2007-12-31 2009-10-29 Boston Scientific Scimed Inc. Bifurcation stent delivery system and methods
USD691268S1 (en) * 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to eye
USD691270S1 (en) * 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to an eye
USD691267S1 (en) * 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to eye
USD691269S1 (en) * 2009-01-07 2013-10-08 Salutaris Medical Devices, Inc. Fixed-shape cannula for posterior delivery of radiation to an eye
US8006365B2 (en) * 2008-01-30 2011-08-30 Easylap Ltd. Device and method for applying rotary tacks
US7959640B2 (en) * 2008-02-13 2011-06-14 Apollo Endosurgery, Inc. Method of performing transgastric ventral hernia repair and tissue anchors and deployment devices therefor
US8888810B2 (en) * 2008-02-20 2014-11-18 Covidien Lp Compound barb medical device and method
US8273105B2 (en) 2008-02-20 2012-09-25 Tyco Healthcare Group Lp Compound barb medical device and method
US8454653B2 (en) * 2008-02-20 2013-06-04 Covidien Lp Compound barb medical device and method
US8998933B2 (en) * 2008-02-28 2015-04-07 Medtronic, Inc. Surgical fastening clips, systems and methods for proximating tissue
US8177836B2 (en) 2008-03-10 2012-05-15 Medtronic, Inc. Apparatus and methods for minimally invasive valve repair
US8733611B2 (en) 2008-03-12 2014-05-27 Covidien Lp Ratcheting mechanism for surgical stapling device
EP2257227A4 (en) 2008-03-14 2014-03-26 Safestitch Medical Inc Hernia stapler with integrated mesh manipulator
US8870049B2 (en) 2008-03-14 2014-10-28 Transenterix, Inc. Hernia stapler
US20090242609A1 (en) * 2008-03-31 2009-10-01 Medtronic Vascular, Inc. Vascular Puncture Closure Staple With Tip Protection
US9034011B2 (en) * 2008-04-01 2015-05-19 Covidien Lp Anchoring device
US20090248070A1 (en) * 2008-04-01 2009-10-01 Kosa Timothy D Anchoring Suture
US8932327B2 (en) * 2008-04-01 2015-01-13 Covidien Lp Anchoring device
US9358002B2 (en) 2008-04-01 2016-06-07 Covidien Lp Anchoring device
US7959648B2 (en) * 2008-04-22 2011-06-14 Medtronic Vascular, Inc. Device and method for effecting hemostasis about a puncture
CA2722406C (en) * 2008-04-23 2013-12-10 Wilson-Cook Medical Inc. Tacking device
US7972370B2 (en) * 2008-04-24 2011-07-05 Medtronic Vascular, Inc. Stent graft system and method of use
US20090287045A1 (en) 2008-05-15 2009-11-19 Vladimir Mitelberg Access Systems and Methods of Intra-Abdominal Surgery
US9282965B2 (en) 2008-05-16 2016-03-15 Abbott Laboratories Apparatus and methods for engaging tissue
US8377108B2 (en) 2008-06-02 2013-02-19 Boston Scientific Scimed, Inc. Staggered two balloon bifurcation catheter assembly and methods
JP5662310B2 (en) 2008-06-05 2015-01-28 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. Shrinkable branch device and manufacturing method thereof
EP2299945B1 (en) 2008-06-05 2016-03-23 Boston Scientific Scimed, Inc. Balloon bifurcated lumen treatment
WO2010004546A1 (en) 2008-06-16 2010-01-14 Valtech Cardio, Ltd. Annuloplasty devices and methods of delivery therefor
US8087142B2 (en) * 2008-07-02 2012-01-03 Easylap Ltd. Pivoting tacker
DE102008040252A1 (en) * 2008-07-08 2010-01-14 Biotronik Vi Patent Ag Delivery system for a medical device having a shell and cover for a delivery system for a medical device
DE102008034534A1 (en) * 2008-07-18 2010-01-21 Aesculap Ag Puncture closure for closing a puncture opening having a hollow organ, in particular a blood vessel
JP2012500098A (en) 2008-08-19 2012-01-05 ウィルソン−クック・メディカル・インコーポレーテッドWilson−Cook Medical Incorporated Instrument for anchor wearing the lymph nodes to resected or tissue during translumenal treatment
US8465502B2 (en) 2008-08-25 2013-06-18 Covidien Lp Surgical clip applier and method of assembly
US8267944B2 (en) 2008-08-29 2012-09-18 Tyco Healthcare Group Lp Endoscopic surgical clip applier with lock out
US8409223B2 (en) 2008-08-29 2013-04-02 Covidien Lp Endoscopic surgical clip applier with clip retention
US8777990B2 (en) 2008-09-08 2014-07-15 Howmedica Osteonics Corp. Knotless suture anchor for soft tissue repair and method of use
US8192461B2 (en) 2008-09-11 2012-06-05 Cook Medical Technologies Llc Methods for facilitating closure of a bodily opening using one or more tacking devices
US8398676B2 (en) 2008-10-30 2013-03-19 Abbott Vascular Inc. Closure device
WO2010053828A1 (en) * 2008-11-04 2010-05-14 Wilson-Cook Medical Inc. Tacking device
US9451942B2 (en) * 2008-11-12 2016-09-27 Howmedica Osteonics Corp. Insertion tool for knotless suture anchor for soft tissue repair and method of use
WO2010062971A9 (en) 2008-11-26 2010-10-07 Anova Corporation Methods and apparatus for anulus repair
EP2373230B1 (en) 2008-12-09 2012-11-28 Cook Medical Technologies LLC Retractable tacking device
US20100145362A1 (en) * 2008-12-09 2010-06-10 Wilson-Cook Medical Inc. Apparatus and methods for controlled release of tacking devices
US20100145429A1 (en) * 2008-12-09 2010-06-10 Cook Incorporated Introducer sheath and method of manufacture
CA2747233C (en) 2008-12-19 2014-08-12 John A. Karpiel Clip devices and methods of delivery and deployment
JP2012512715A (en) * 2008-12-19 2012-06-07 クック メディカル テクノロジーズ エルエルシーCook Medical Technologies Llc Tack instrument thickness changes, and a method of delivery and deployment
US9011530B2 (en) 2008-12-22 2015-04-21 Valtech Cardio, Ltd. Partially-adjustable annuloplasty structure
US8858594B2 (en) 2008-12-22 2014-10-14 Abbott Laboratories Curved closure device
US8241351B2 (en) * 2008-12-22 2012-08-14 Valtech Cardio, Ltd. Adjustable partial annuloplasty ring and mechanism therefor
CN102341063B (en) 2008-12-22 2015-11-25 瓦尔泰克卡迪欧有限公司 Adjusting device and the adjustable annuloplasty mechanism
US8147542B2 (en) 2008-12-22 2012-04-03 Valtech Cardio, Ltd. Adjustable repair chords and spool mechanism therefor
US8545553B2 (en) 2009-05-04 2013-10-01 Valtech Cardio, Ltd. Over-wire rotation tool
US9968452B2 (en) 2009-05-04 2018-05-15 Valtech Cardio, Ltd. Annuloplasty ring delivery cathethers
US9179910B2 (en) 2009-03-20 2015-11-10 Rotation Medical, Inc. Medical device delivery system and method
US20100191332A1 (en) 2009-01-08 2010-07-29 Euteneuer Charles L Implantable Tendon Protection Systems and Related Kits and Methods
US9414820B2 (en) 2009-01-09 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US9089311B2 (en) 2009-01-09 2015-07-28 Abbott Vascular Inc. Vessel closure devices and methods
US9486191B2 (en) 2009-01-09 2016-11-08 Abbott Vascular, Inc. Closure devices
US9173644B2 (en) 2009-01-09 2015-11-03 Abbott Vascular Inc. Closure devices, systems, and methods
US20100179589A1 (en) 2009-01-09 2010-07-15 Abbott Vascular Inc. Rapidly eroding anchor
US20100185234A1 (en) 2009-01-16 2010-07-22 Abbott Vascular Inc. Closure devices, systems, and methods
US9943704B1 (en) 2009-01-21 2018-04-17 Varian Medical Systems, Inc. Method and system for fiducials contained in removable device for radiation therapy
US8353956B2 (en) 2009-02-17 2013-01-15 Valtech Cardio, Ltd. Actively-engageable movement-restriction mechanism for use with an annuloplasty structure
US8905937B2 (en) 2009-02-26 2014-12-09 Integrated Vascular Systems, Inc. Methods and apparatus for locating a surface of a body lumen
US8518060B2 (en) 2009-04-09 2013-08-27 Medtronic, Inc. Medical clip with radial tines, system and method of using same
US20100274266A1 (en) * 2009-04-22 2010-10-28 Ofir Rimer Rotary tack
US8668704B2 (en) 2009-04-24 2014-03-11 Medtronic, Inc. Medical clip with tines, system and method of using same
DE202009018081U1 (en) 2009-04-27 2010-12-30 Haindl, Hans, Dr. Surgical clip and applicator
US8715342B2 (en) 2009-05-07 2014-05-06 Valtech Cardio, Ltd. Annuloplasty ring with intra-ring anchoring
US8920439B2 (en) 2009-05-12 2014-12-30 Ethicon, Inc. Applicator instruments having curved and articulating shafts for deploying surgical fasteners and methods therefor
US8894669B2 (en) 2009-05-12 2014-11-25 Ethicon, Inc. Surgical fasteners, applicator instruments, and methods for deploying surgical fasteners
US9055945B2 (en) 2009-05-12 2015-06-16 Ethicon, Inc. Surgical fasteners having articulating joints and deflectable tips
USD744646S1 (en) 2009-05-12 2015-12-01 Ethicon, Inc. Surgical fastener
US8579920B2 (en) 2009-05-12 2013-11-12 Ethicon, Inc. Surgical fasteners, applicator instruments, and methods for deploying surgical fasteners
US8728098B2 (en) * 2009-05-12 2014-05-20 Ethicon, Inc. Surgical fasteners, applicator instruments, and methods for deploying surgical fasteners
USD698021S1 (en) 2009-05-12 2014-01-21 Ethicon, Inc. Surgical fastener
US8728099B2 (en) 2009-05-12 2014-05-20 Ethicon, Inc. Surgical fasteners, applicator instruments, and methods for deploying surgical fasteners
US7960600B2 (en) 2009-05-28 2011-06-14 Uop Llc Process for improved meta-xylene yield from C8 aromatics
EP2434960A1 (en) * 2009-05-28 2012-04-04 Cook Medical Technologies LLC Tacking device and methods of deployment
WO2010141906A1 (en) 2009-06-04 2010-12-09 Rotation Medical, Inc. Methods and apparatus for deploying sheet-like materials
US8763878B2 (en) 2009-06-04 2014-07-01 Rotation Medical, Inc. Methods and apparatus having bowstring-like staple delivery to a target tissue
US8821514B2 (en) 2009-06-08 2014-09-02 Covidien Lp Powered tack applier
US8500757B2 (en) * 2009-07-28 2013-08-06 Edwards Lifesciences Corporation Surgical puncture cinch and closure system
US8459524B2 (en) * 2009-08-14 2013-06-11 Covidien Lp Tissue fastening system for a medical device
US20110054492A1 (en) 2009-08-26 2011-03-03 Abbott Laboratories Medical device for repairing a fistula
JP2013505114A (en) * 2009-09-22 2013-02-14 アルスタシス,インコーポレイテッドArstasis,Inc. Apparatus for forming a tube in tissue, methods, and kits
US20110166555A1 (en) * 2009-09-30 2011-07-07 Jianbo Zhou Carrier for an insertable medical device, insertion tools, methods of use, and kits
CA2777495A1 (en) 2009-10-26 2011-05-12 Cardiokinetix, Inc. Ventricular volume reduction
US9011520B2 (en) 2009-10-29 2015-04-21 Valtech Cardio, Ltd. Tissue anchor for annuloplasty device
US9180007B2 (en) 2009-10-29 2015-11-10 Valtech Cardio, Ltd. Apparatus and method for guide-wire based advancement of an adjustable implant
US8940042B2 (en) * 2009-10-29 2015-01-27 Valtech Cardio, Ltd. Apparatus for guide-wire based advancement of a rotation assembly
US10098737B2 (en) 2009-10-29 2018-10-16 Valtech Cardio, Ltd. Tissue anchor for annuloplasty device
CN102792033A (en) * 2009-11-02 2012-11-21 普库有限公司 The flexible spring fastener
US9682180B2 (en) * 2009-11-15 2017-06-20 Thoratec Corporation Attachment system, device and method
US20110118833A1 (en) * 2009-11-15 2011-05-19 Thoratec Corporation Attachment device and method
EP2506777A4 (en) 2009-12-02 2015-02-11 Valtech Cardio Ltd Delivery tool for implantation of spool assembly coupled to a helical anchor
US9186136B2 (en) 2009-12-09 2015-11-17 Covidien Lp Surgical clip applier
US8545486B2 (en) 2009-12-15 2013-10-01 Covidien Lp Surgical clip applier
US8652153B2 (en) 2010-01-11 2014-02-18 Anulex Technologies, Inc. Intervertebral disc annulus repair system and bone anchor delivery tool
US20110208212A1 (en) 2010-02-19 2011-08-25 Zergiebel Earl M Surgical clip applier
US8683895B2 (en) 2010-02-23 2014-04-01 Kensey Nash Corporation Single revolution snap action drive for surgical fasteners
US8403945B2 (en) * 2010-02-25 2013-03-26 Covidien Lp Articulating endoscopic surgical clip applier
US9198750B2 (en) 2010-03-11 2015-12-01 Rotation Medical, Inc. Tendon repair implant and method of arthroscopic implantation
WO2011162287A1 (en) * 2010-06-22 2011-12-29 オリンパスメディカルシステムズ株式会社 Tissue clamp production method and tissue clamp
US8523881B2 (en) 2010-07-26 2013-09-03 Valtech Cardio, Ltd. Multiple anchor delivery tool
US8968337B2 (en) 2010-07-28 2015-03-03 Covidien Lp Articulating clip applier
US8403946B2 (en) 2010-07-28 2013-03-26 Covidien Lp Articulating clip applier cartridge
US8758399B2 (en) 2010-08-02 2014-06-24 Abbott Cardiovascular Systems, Inc. Expandable bioabsorbable plug apparatus and method
US20120053680A1 (en) 2010-08-24 2012-03-01 Bolling Steven F Reconfiguring Heart Features
EP2608723A4 (en) * 2010-08-26 2015-09-23 Pavilion Medical Innovations Helical fasteners and methods for deploying same
US8414612B2 (en) 2010-11-08 2013-04-09 Covidien Lp Multifilament barbed suture
US8821534B2 (en) 2010-12-06 2014-09-02 Integrated Vascular Systems, Inc. Clip applier having improved hemostasis and methods of use
JP6130302B2 (en) * 2011-01-28 2017-05-17 アピカ カーディオヴァスキュラー リミテッド System for sealing the puncture wound of the tissue wall
EP2670346A2 (en) 2011-02-01 2013-12-11 Georgia Tech Research Corporation Systems for implanting and using a conduit within a tissue wall
WO2012145059A1 (en) 2011-02-15 2012-10-26 Rotation Medical, Inc. Methods and apparatus for fixing sheet-like materials to a target tissue
WO2012112565A3 (en) 2011-02-15 2013-01-17 Rotation Medical, Inc. Methods and apparatus for delivering and positioning sheet-like materials
CA2827870A1 (en) * 2011-02-25 2012-08-30 Thoratec Corporation Coupling system, applicator tool, attachment ring and method for connecting a conduit to biological tissue
WO2012121705A1 (en) * 2011-03-08 2012-09-13 Synthes Usa, Llc Flexible helical fixation device
US9149276B2 (en) 2011-03-21 2015-10-06 Abbott Cardiovascular Systems, Inc. Clip and deployment apparatus for tissue closure
US9427225B2 (en) * 2011-03-25 2016-08-30 Smith & Nephew, Inc. Tissue lifting
US9775623B2 (en) 2011-04-29 2017-10-03 Covidien Lp Surgical clip applier including clip relief feature
US9943392B2 (en) 2011-05-04 2018-04-17 Boston Scientific Scimed, Inc. Implants, tools, and methods for treatment of pelvic conditions
US9510825B2 (en) * 2011-05-05 2016-12-06 Astora Women's Health, Llc Tools and methods for treatment of pelvic conditions
WO2012158919A3 (en) 2011-05-18 2013-02-21 Thoratec Corporation Coring knife
US9918840B2 (en) 2011-06-23 2018-03-20 Valtech Cardio, Ltd. Closed band for percutaneous annuloplasty
US8940044B2 (en) 2011-06-23 2015-01-27 Valtech Cardio, Ltd. Closure element for use with an annuloplasty structure
US8926697B2 (en) 2011-06-23 2015-01-06 Valtech Cardio, Ltd. Closed band for percutaneous annuloplasty
US9364326B2 (en) 2011-06-29 2016-06-14 Mitralix Ltd. Heart valve repair devices and methods
JP2013013490A (en) * 2011-07-01 2013-01-24 Olympus Corp Tissue-securing device
FR2977471B1 (en) * 2011-07-07 2013-07-05 Aspide Medical Device comprising a plurality of implants for the fixation of prosthetic material
US9955957B2 (en) 2011-09-09 2018-05-01 Endogastric Solutions, Inc. Methods and devices for manipulating and fastening tissue
US20130066338A1 (en) 2011-09-09 2013-03-14 Richard Romley Methods and devices for manipulating and fastening tissue
US9572571B2 (en) 2011-09-09 2017-02-21 Endogastric Solutions, Inc. Methods and devices for manipulating and fastening tissue
WO2013038410A1 (en) 2011-09-15 2013-03-21 I.B.I. Israel Biomedical Innovations Ltd. Surgical fastener having a snap lock and devices deploying it
US9801633B2 (en) 2011-09-26 2017-10-31 Artack Medical (2013) Ltd. Surgical fastening device and method
WO2013066946A1 (en) 2011-11-01 2013-05-10 Ellipse Technologies, Inc. Adjustable magnetic devices and methods of using same
US8858623B2 (en) 2011-11-04 2014-10-14 Valtech Cardio, Ltd. Implant having multiple rotational assemblies
WO2013069436A1 (en) * 2011-11-07 2013-05-16 オリンパスメディカルシステムズ株式会社 Implant placement device
EP2775896A4 (en) 2011-11-08 2016-08-03 Valtech Cardio Ltd Controlled steering functionality for implant-delivery tool
WO2014064694A3 (en) 2012-10-23 2014-06-19 Valtech Cardio, Ltd. Controlled steering functionality for implant-delivery tool
US9486213B2 (en) * 2011-11-14 2016-11-08 Thd Lap Ltd. Drive mechanism for articulating tacker
US9332976B2 (en) 2011-11-30 2016-05-10 Abbott Cardiovascular Systems, Inc. Tissue closure device
US8968336B2 (en) 2011-12-07 2015-03-03 Edwards Lifesciences Corporation Self-cinching surgical clips and delivery system
US9173657B2 (en) 2011-12-15 2015-11-03 Ethicon Endo-Surgery, Inc. Devices and methods for endoluminal plication
US9113866B2 (en) 2011-12-15 2015-08-25 Ethicon Endo-Surgery, Inc. Devices and methods for endoluminal plication
US8535339B2 (en) 2011-12-18 2013-09-17 Via Surgical Ltd. Apparatus and method for suturing
US9888913B2 (en) 2012-05-31 2018-02-13 Via Surgical Ltd. Variable depth surgical fixation
EP2854659A1 (en) * 2012-05-31 2015-04-08 Via Surgical Ltd. Variable depth surgical fixation
WO2013119321A1 (en) 2011-12-19 2013-08-15 Rotation Medical, Inc. Fasteners for affixing sheet -like materials to bone or tissue
US9271726B2 (en) 2011-12-19 2016-03-01 Rotation Medical, Inc. Fasteners and fastener delivery devices for affixing sheet-like materials to bone or tissue
US9107661B2 (en) 2011-12-19 2015-08-18 Rotation Medical, Inc. Fasteners and fastener delivery devices for affixing sheet-like materials to bone or tissue
US9364239B2 (en) 2011-12-19 2016-06-14 Covidien Lp Jaw closure mechanism for a surgical clip applier
WO2013093921A1 (en) 2011-12-20 2013-06-27 Collplant Ltd. Collagen coated synthetic polymer fibers
US9017347B2 (en) 2011-12-22 2015-04-28 Edwards Lifesciences Corporation Suture clip deployment devices
US9364216B2 (en) 2011-12-29 2016-06-14 Covidien Lp Surgical clip applier with integrated clip counter
WO2013101641A3 (en) 2011-12-29 2013-08-22 Rotation Medical, Inc. Anatomical location markers and methods of use in positioning sheet-like materials during surgery
WO2013101640A1 (en) 2011-12-29 2013-07-04 Rotation Medical, Inc. Guidewire having a distal fixation member for delivering and positioning sheet-like materials in surgery
US9107654B2 (en) 2012-01-05 2015-08-18 Cook Medical Technologies Llc Attachment device for tissue approximation and retraction
US9220492B2 (en) 2012-02-01 2015-12-29 Covidien Lp Wound closure device
US9107660B2 (en) 2012-02-01 2015-08-18 Covidien Lp Wound closure device
US9750616B2 (en) 2012-02-17 2017-09-05 Spinal Elements, Inc. Interbody fusion device
US8740919B2 (en) 2012-03-16 2014-06-03 Ethicon, Inc. Devices for dispensing surgical fasteners into tissue while simultaneously generating external marks that mirror the number and location of the dispensed surgical fasteners
US9119617B2 (en) 2012-03-16 2015-09-01 Ethicon, Inc. Clamping devices for dispensing surgical fasteners into soft media
US8992547B2 (en) 2012-03-21 2015-03-31 Ethicon Endo-Surgery, Inc. Methods and devices for creating tissue plications
US9265514B2 (en) 2012-04-17 2016-02-23 Miteas Ltd. Manipulator for grasping tissue
WO2013162741A1 (en) 2012-04-23 2013-10-31 Thoratec Corporation Engagement device and method for deployment of anastomotic clips
US9408610B2 (en) 2012-05-04 2016-08-09 Covidien Lp Surgical clip applier with dissector
US9364228B2 (en) 2012-05-11 2016-06-14 Ethicon, Llc Applicator instruments having distal end caps for facilitating the accurate placement of surgical fasteners during open repair procedures
US8518055B1 (en) 2012-05-11 2013-08-27 Ethicon, Inc. Applicator instruments for dispensing surgical fasteners during open repair procedures
US20130303845A1 (en) 2012-05-11 2013-11-14 Ethicon, Inc. Applicator instruments with imaging systems for dispensing surgical fasteners during open repair procedures
US9681975B2 (en) 2012-05-31 2017-06-20 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9451960B2 (en) 2012-05-31 2016-09-27 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9050168B2 (en) 2012-05-31 2015-06-09 Valentx, Inc. Devices and methods for gastrointestinal bypass
US9827401B2 (en) 2012-06-01 2017-11-28 Surmodics, Inc. Apparatus and methods for coating medical devices
EP2855030A1 (en) 2012-06-01 2015-04-08 SurModics, Inc. Apparatus and method for coating balloon catheters
US9087694B2 (en) 2012-06-03 2015-07-21 Silicon Solar Solutions, Llc Ultra-large grain polycrystalline semiconductors through top-down aluminum induced crystallization (TAIC)
US9554836B2 (en) * 2012-06-29 2017-01-31 The Cleveland Clinic Foundation Intramedullary bone stent
US9498202B2 (en) 2012-07-10 2016-11-22 Edwards Lifesciences Corporation Suture securement devices
US9289207B2 (en) * 2012-11-29 2016-03-22 Ethicon Endo-Surgery, Llc Surgical staple with integral pledget for tip deflection
US9730793B2 (en) 2012-12-06 2017-08-15 Valtech Cardio, Ltd. Techniques for guide-wire based advancement of a tool
US9161754B2 (en) 2012-12-14 2015-10-20 Endogastric Solutions, Inc. Apparatus and method for concurrently forming a gastroesophageal valve and tightening the lower esophageal sphincter
US9592047B2 (en) 2012-12-21 2017-03-14 Edwards Lifesciences Corporation System for securing sutures
US9364209B2 (en) 2012-12-21 2016-06-14 Abbott Cardiovascular Systems, Inc. Articulating suturing device
US9113892B2 (en) 2013-01-08 2015-08-25 Covidien Lp Surgical clip applier
US9968362B2 (en) 2013-01-08 2018-05-15 Covidien Lp Surgical clip applier
US9351733B2 (en) 2013-01-18 2016-05-31 Covidien Lp Surgical fastener applier
WO2014117087A1 (en) 2013-01-25 2014-07-31 Apica Cardiovascular Limited Systems and methods for percutaneous access, stabilization and closure of organs
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
ES2684316T3 (en) 2013-03-11 2018-10-02 Via Surgical Ltd. Surgical quality indicator stitcher
US9358010B2 (en) 2013-03-12 2016-06-07 Covidien Lp Flex cable and spring-loaded tube for tacking device
US9757264B2 (en) 2013-03-13 2017-09-12 Valentx, Inc. Devices and methods for gastrointestinal bypass
US20140276968A1 (en) 2013-03-14 2014-09-18 Ethicon, Inc. Applicator systems for surgical fasteners
US9474530B2 (en) 2013-03-14 2016-10-25 C.R. Bard, Inc. Handling of fasteners within a surgical instrument
US9867620B2 (en) 2013-03-14 2018-01-16 Covidien Lp Articulation joint for apparatus for endoscopic procedures
US9427230B2 (en) * 2013-03-14 2016-08-30 C.R. Bard, Inc. Handling of fasteners within a surgical instrument
US9655621B2 (en) * 2013-03-15 2017-05-23 Covidien Lp Surgical instrument for dispensing tacks and solution
US9358004B2 (en) 2013-06-28 2016-06-07 Covidien Lp Articulating apparatus for endoscopic procedures
US10085746B2 (en) 2013-06-28 2018-10-02 Covidien Lp Surgical instrument including rotating end effector and rotation-limiting structure
US9351728B2 (en) 2013-06-28 2016-05-31 Covidien Lp Articulating apparatus for endoscopic procedures
US9668730B2 (en) 2013-06-28 2017-06-06 Covidien Lp Articulating apparatus for endoscopic procedures with timing system
CN105073026B (en) 2013-07-11 2018-02-02 爱德华兹生命科学公司 Knotless suture anchor installation system
US9526498B2 (en) 2013-09-17 2016-12-27 Covidien Lp Surgical device with a trigger lockout mechanism device
US10016193B2 (en) 2013-11-18 2018-07-10 Edwards Lifesciences Ag Multiple-firing crimp device and methods for using and manufacturing same
EP3071123A4 (en) * 2013-11-18 2018-05-30 Medtronic Vascular Inc. Multi-fire fastener delivery system and method
US9610162B2 (en) 2013-12-26 2017-04-04 Valtech Cardio, Ltd. Implantation of flexible implant
US9681864B1 (en) 2014-01-03 2017-06-20 Harpoon Medical, Inc. Method and apparatus for transapical procedures on a mitral valve
US20150272584A1 (en) * 2014-03-31 2015-10-01 Coloplast A/S Adapter attachable to a shaft of an anchor delivery tool
EP3136987A1 (en) * 2014-04-28 2017-03-08 Aesculap AG Medical shaft-type instrument with a support plate/bridge on the retaining rail
US20150305738A1 (en) * 2014-04-28 2015-10-29 Covidien Lp Surgical fastener having a cap
US9877714B2 (en) * 2014-06-04 2018-01-30 Neotract, Inc. System with reloadable handle for delivering an anchor
US9700412B2 (en) 2014-06-26 2017-07-11 Mitralix Ltd. Heart valve repair devices for placement in ventricle and delivery systems for implanting heart valve repair devices
US9180005B1 (en) 2014-07-17 2015-11-10 Millipede, Inc. Adjustable endolumenal mitral valve ring
USD754855S1 (en) 2014-11-24 2016-04-26 Ethicon, Inc. Curved tissue fastening device
US9931124B2 (en) 2015-01-07 2018-04-03 Covidien Lp Reposable clip applier
CN107530166A (en) 2015-02-13 2018-01-02 魅尔皮德股份有限公司 Valve replacement using rotational anchors
US20160310633A1 (en) 2015-04-23 2016-10-27 Covidien Lp Adhesive compositions
EP3288501A1 (en) 2015-04-29 2018-03-07 Institute For Musculoskeletal Science And Education, Ltd. Coiled implants and systems and methods of use thereof
US10004499B2 (en) 2015-05-19 2018-06-26 Ethicon, Llc Applicator instruments having end caps with gripping features
US10092286B2 (en) 2015-05-27 2018-10-09 Covidien Lp Suturing loading unit
US10028733B2 (en) 2015-05-28 2018-07-24 National University Of Ireland, Galway Fistula treatment device
EP3302291A1 (en) * 2015-05-28 2018-04-11 National University of Ireland Galway A fistula treatment device
US20160354192A1 (en) 2015-06-04 2016-12-08 Covidien Lp Ventral hernia defect closure
WO2017031037A1 (en) * 2015-08-14 2017-02-23 Willis Timothy R Intraocular lenses (iols) and related assemblies and intraocular attachment methods
US20170135693A1 (en) 2015-11-17 2017-05-18 Ethicon, Inc. Applicator instruments for dispensing surgical fasteners having articulating shafts and articulation control elements
US20170156728A1 (en) 2015-12-02 2017-06-08 Filippo Bastia Surgical fasteners with indication of fastener amount
CN105434001B (en) * 2015-12-24 2018-09-28 派尔特(苏州)医疗科技有限公司 Hernia staple device
US20170181826A1 (en) 2015-12-28 2017-06-29 Ethicon, Inc. Applicator instruments having off-axis surgical fastener delivery
EP3257455A1 (en) * 2016-06-17 2017-12-20 National University of Ireland, Galway A fistula treatment device
US20180078354A1 (en) 2016-09-21 2018-03-22 Ethicon, Inc. Applicator instruments for dispensing surgical fasteners having articulating shafts
USD804666S1 (en) 2016-12-29 2017-12-05 Ethicon, Inc. Surgical fastener

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US28932A (en) * 1860-06-26 Railroad station-indicator
DE295962C (en) *
FR320731A (en) * 1902-04-28 1902-12-18 Brown Haydn Clamp for surgical operations and clamp to be used
US2033039A (en) * 1935-05-22 1936-03-03 Arthur A Limpert Double point rotary pin
US2391792A (en) * 1942-01-23 1945-12-25 Johns Manville Wall construction and fastener therefor
US3638654A (en) * 1969-07-11 1972-02-01 Uche Akuba Suturing instrument
USRE28932E (en) * 1972-09-29 1976-08-17 United States Surgical Corporation Surgical stapling instrument
US3858783A (en) * 1972-11-20 1975-01-07 Nikolai Nikolaevich Kapitanov Surgical instrument for stitching up tissues with lengths of suture wire
US3870048A (en) * 1973-07-30 1975-03-11 In Bae Yoon Device for sterilizing the human female or male by ligation
FR2299548A1 (en) * 1975-01-30 1976-08-27 Melin Raymond Wire attachment element for corrugated cardboard cartons - has corkscrew form with bevelled end and insertion tool with chuck to match
US4084594A (en) * 1976-10-08 1978-04-18 American Hospital Supply Corporation Surgical instrument and handle assembly therefor
US4406363A (en) 1982-09-24 1983-09-27 Ethicon, Inc. Folder retainer for multistrand surgical sutures
US4595007A (en) * 1983-03-14 1986-06-17 Ethicon, Inc. Split ring type tissue fastener
US4627437A (en) * 1983-06-20 1986-12-09 Ethicon, Inc. Method of applying a fastener to tissue with a pair of hollow needles
GB2148232B (en) 1983-10-19 1987-06-10 Ethicon Inc Multi-strand suture package for single suture dispensing
US4596350A (en) * 1984-05-10 1986-06-24 Senmed, Inc. Surgical stapler drive apparatus
US4628943A (en) * 1985-06-21 1986-12-16 Cordis Corporation Bipolar screw-in packing lead assembly
US4924865A (en) * 1986-05-20 1990-05-15 Concept, Inc. Repair tack for bodily tissue
US4951860A (en) * 1987-12-28 1990-08-28 Edward Weck & Co. Method and apparatus for storing, dispensing and applying surgical staples
US4950276A (en) 1988-02-25 1990-08-21 Vince Dennis J Prosthesis for banding of an artery capable of dilation by a balloon dilator
US5222976A (en) * 1989-05-16 1993-06-29 Inbae Yoon Suture devices particularly useful in endoscopic surgery
US5053047A (en) * 1989-05-16 1991-10-01 Inbae Yoon Suture devices particularly useful in endoscopic surgery and methods of suturing
US5018530A (en) 1989-06-15 1991-05-28 Research Corporation Technologies, Inc. Helical-tipped lesion localization needle device and method of using the same
US5100420A (en) * 1989-07-18 1992-03-31 United States Surgical Corporation Apparatus and method for applying surgical clips in laparoscopic or endoscopic procedures
US5007921A (en) * 1989-10-26 1991-04-16 Brown Alan W Surgical staple
US5222961A (en) * 1989-12-26 1993-06-29 Naomi Nakao Endoscopic stapling device and related staple
US4980959A (en) * 1990-01-26 1991-01-01 Vsi Corporation Installation tool for helical coil inserts
EP0442282B1 (en) 1990-02-13 1994-04-06 Palitex Project-Company GmbH Textile machine, in particular twisting machine
US5282807A (en) * 1990-11-05 1994-02-01 Knoepfler Dennis J Automatic stapler for laparoscopic procedure with selective cutter, nontraumatic jaws and suction irrigator
US5160341A (en) * 1990-11-08 1992-11-03 Advanced Surgical Intervention, Inc. Resorbable urethral stent and apparatus for its insertion
US5171249A (en) 1991-04-04 1992-12-15 Ethicon, Inc. Endoscopic multiple ligating clip applier
US5171247A (en) * 1991-04-04 1992-12-15 Ethicon, Inc. Endoscopic multiple ligating clip applier with rotating shaft
US5203864A (en) 1991-04-05 1993-04-20 Phillips Edward H Surgical fastener system
US5297714A (en) * 1991-04-17 1994-03-29 Ethicon, Inc. Surgical staple with modified "B" shaped configuration
US5356064A (en) * 1991-10-18 1994-10-18 United States Surgical Corporation Apparatus and method for applying surgical staples to attach an object to body tissue
US5372600A (en) * 1991-10-31 1994-12-13 Instent Inc. Stent delivery systems
US5258000A (en) * 1991-11-25 1993-11-02 Cook Incorporated Tissue aperture repair device
US5259395A (en) * 1992-01-15 1993-11-09 Siemens Pacesetter, Inc. Pacemaker lead with extendable retractable lockable fixing helix
US5433721A (en) * 1992-01-17 1995-07-18 Ethicon, Inc. Endoscopic instrument having a torsionally stiff drive shaft for applying fasteners to tissue
EP0554653A3 (en) 1992-01-24 1993-08-25 American Cyanamid Company Multicolored surgical braid
US5318575A (en) 1992-02-03 1994-06-07 United States Surgical Corporation Method of using a surgical repair suture product
US5217486A (en) * 1992-02-18 1993-06-08 Mitek Surgical Products, Inc. Suture anchor and installation tool
US5163343A (en) * 1992-02-21 1992-11-17 Gish Donald A System for fastening plies of fabric
US5228565A (en) 1992-02-26 1993-07-20 United States Surgical Corporation Package and method of loading for resilient surgical sutures
DE4303374A1 (en) 1992-03-12 1993-09-23 Wolf Gmbh Richard
US5242457A (en) * 1992-05-08 1993-09-07 Ethicon, Inc. Surgical instrument and staples for applying purse string sutures
US5258007A (en) * 1992-05-14 1993-11-02 Robert F. Spetzler Powered surgical instrument
DE4217202C2 (en) * 1992-05-23 1994-06-23 Kernforschungsz Karlsruhe A surgical suturing
US5192288A (en) * 1992-05-26 1993-03-09 Origin Medsystems, Inc. Surgical clip applier
US5269792A (en) * 1992-05-26 1993-12-14 Origin Medsystems, Inc. Surgical clip
US5772668A (en) 1992-06-18 1998-06-30 American Biomed, Inc. Apparatus for placing an endoprosthesis
US5437266A (en) * 1992-07-02 1995-08-01 Mcpherson; William Coil screw surgical retractor
US5212865A (en) * 1992-07-20 1993-05-25 Usi Corporation Tool for installation of tanged and tangless wire inserts
US5309927A (en) 1992-10-22 1994-05-10 Ethicon, Inc. Circular stapler tissue retention spring method
DE4304353A1 (en) * 1992-10-24 1994-04-28 Helmut Dipl Ing Wurster Suturing device used in endoscopic surgical operations - has helical needle with fixed non-traumatic thread held and rotated by rollers attached to instrument head extended into patients body.
US5356424A (en) * 1993-02-05 1994-10-18 American Cyanamid Co. Laparoscopic suturing device
US5456145A (en) * 1993-02-16 1995-10-10 Kato Spring Works Company, Ltd. Installation tool for tangless helically coiled insert
US5320630A (en) * 1993-02-23 1994-06-14 Munir Ahmed Endoscopic ligating instrument for applying elastic bands
BE1006874A6 (en) 1993-03-31 1995-01-10 Ceuppens Johan Screw affixing system to affix a net to underlying tissue developed for usein endoscopic surgery or in videoscopic supportive surgery
US5372604A (en) * 1993-06-18 1994-12-13 Linvatec Corporation Suture anchor for soft tissue fixation
US5411522A (en) * 1993-08-25 1995-05-02 Linvatec Corporation Unitary anchor for soft tissue fixation
GB2282328B (en) 1993-09-29 1997-10-08 Johnson & Johnson Medical Absorbable structures for ligament and tendon repair
US5607436A (en) 1993-10-08 1997-03-04 United States Surgical Corporation Apparatus for applying surgical clips
DE4335659C1 (en) 1993-10-15 1995-05-04 Ethicon Gmbh Package with surgical suture
US5487500A (en) * 1994-02-03 1996-01-30 Ethicon Endo-Surgery, Inc. Surgical stapler instrument
US5573548A (en) 1994-06-09 1996-11-12 Zimmer, Inc. Suture anchor
US5626613A (en) * 1995-05-04 1997-05-06 Arthrex, Inc. Corkscrew suture anchor and driver
US5662583A (en) * 1995-08-18 1997-09-02 Khouri Biomedical Research, Inc. Mechanical soft tissue enlarger
US5662683A (en) * 1995-08-22 1997-09-02 Ortho Helix Limited Open helical organic tissue anchor and method of facilitating healing
US5704748A (en) 1996-09-23 1998-01-06 Criswell; Richard Self-locking machine screw

Cited By (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050059956A1 (en) * 2000-08-30 2005-03-17 The Johns Hopkins University Devices for intraocular drug delivery
US8096972B2 (en) 2000-08-30 2012-01-17 Johns Hopkins University Devices for intraocular drug delivery
US10098640B2 (en) 2001-12-04 2018-10-16 Atricure, Inc. Left atrial appendage devices and methods
US7749239B2 (en) 2003-04-28 2010-07-06 De Winter Erwin Screw-device for anastomosis
CN1771011B (en) 2003-04-28 2011-08-31 埃尔温·德温特 Anchoring screw device
US20060241659A1 (en) * 2003-04-28 2006-10-26 Umc Utrecht Holding B.V. Screw-device for anastomosis
US20060259050A1 (en) * 2003-04-28 2006-11-16 De Winter Erwin Screw-device for anastomosis
WO2004096059A1 (en) * 2003-04-28 2004-11-11 Erwin De Winter Screw-device for anastomosis
CN100506309C (en) 2003-04-28 2009-07-01 埃尔温·德温特 Anchoring screw device
US8114099B2 (en) 2004-04-27 2012-02-14 Tyco Healthcare Group Lp Absorbable anchor for hernia mesh fixation
US20110022065A1 (en) * 2004-04-27 2011-01-27 Shipp John I Absorbable anchor for hernia mesh fixation
US20110071556A1 (en) * 2004-04-27 2011-03-24 Tyco Healthcare Group Lp Absorbable anchor for hernia mesh fixation
US20100312258A1 (en) * 2004-04-27 2010-12-09 Tyco Healthcare Group Lp Surgery delivery device and mesh anchor
US8216272B2 (en) 2004-04-27 2012-07-10 Tyco Healthcare Group Lp Absorbable anchor for hernia mesh fixation
US7758612B2 (en) 2004-04-27 2010-07-20 Tyco Healthcare Group Lp Surgery delivery device and mesh anchor
US8282670B2 (en) 2004-04-27 2012-10-09 Tyco Healthcare Group Lp Surgery delivery device and mesh anchor
US7645285B2 (en) 2004-05-26 2010-01-12 Idx Medical, Ltd Apparatus and methods for occluding a hollow anatomical structure
US20050277959A1 (en) * 2004-05-26 2005-12-15 Idx Medical, Ltd. Apparatus and methods for occluding a hollow anatomical structure
US8876820B2 (en) 2004-10-20 2014-11-04 Atricure, Inc. Surgical clamp
US20090012545A1 (en) * 2005-07-14 2009-01-08 Idx Medical, Ltd. Apparatus and Methods for Occluding a Hallow Anatomical Structure
US7862573B2 (en) 2006-04-21 2011-01-04 Darois Roger E Method and apparatus for surgical fastening
US20070250064A1 (en) * 2006-04-21 2007-10-25 Davol, Inc. Method and apparatus for surgical fastening
US20110092992A1 (en) * 2006-04-21 2011-04-21 Darois Roger E Method and apparatus for surgical fastening
US8979874B2 (en) 2006-04-21 2015-03-17 Davol, Inc. Method and apparatus for surgical fastening
US9271725B2 (en) 2006-07-18 2016-03-01 Davol, Inc. Method and apparatus for surgical fastening
US9408659B2 (en) 2007-04-02 2016-08-09 Atricure, Inc. Surgical instrument with separate tool head and method of use
EP2057948A3 (en) * 2007-11-06 2009-09-30 Tyco Healthcare Group, LP Coated surgical staples and an illuminated staple cartridge for a surgical stapling instrument
US7954687B2 (en) 2007-11-06 2011-06-07 Tyco Healthcare Group Lp Coated surgical staples and an illuminated staple cartridge for a surgical stapling instrument
EP2476379A1 (en) * 2007-11-06 2012-07-18 Tyco Healthcare Group, LP Coated surgical staples and an illuminated staple cartridge for a surgical stapling instrument
US20090114701A1 (en) * 2007-11-06 2009-05-07 Tyco Healthcare Group Lp Coated Surgical Staples and an Illuminated Staple Cartridge for a Surgical Stapling Instrument
US8162958B2 (en) 2008-07-11 2012-04-24 Olympus Medical Systems Corp. Tissue fastening tool and applicator for indwelling the same within body, and tissue fastening method through natural orifice
US8932305B2 (en) 2008-07-11 2015-01-13 Olympus Medical Systems Corp. Tissue fastening method
US20100010520A1 (en) * 2008-07-11 2010-01-14 Olympus Medical Systems Corp. Tissue fastener
US9662114B2 (en) 2008-07-11 2017-05-30 Olympus Corporation Method of forming through hole
US8828026B2 (en) 2008-07-11 2014-09-09 Olympus Medical Systems Corp. Tissue fastening apparatus
US8852218B2 (en) 2008-07-21 2014-10-07 AtriCore, Inc. Apparatus and methods for occluding an anatomical structure
US20100189765A1 (en) * 2008-11-26 2010-07-29 Erickson Signe R Implantable ocular drug delivery device and methods
US20100179570A1 (en) * 2009-01-13 2010-07-15 Salvatore Privitera Apparatus and methods for deploying a clip to occlude an anatomical structure
US9393023B2 (en) 2009-01-13 2016-07-19 Atricure, Inc. Apparatus and methods for deploying a clip to occlude an anatomical structure
WO2011015789A1 (en) * 2009-08-06 2011-02-10 Textile Hi-Tec (T.H.T.) Fastener for a mechanical suture
FR2948867A1 (en) * 2009-08-06 2011-02-11 Textile Hi Tec T H T Clip for mechanical suture
US20110295282A1 (en) * 2010-05-26 2011-12-01 Tyco Healthcare Group Lp Fastener and drive method for soft tissue repair
US9017349B2 (en) 2010-10-27 2015-04-28 Atricure, Inc. Appendage clamp deployment assist device
US9066741B2 (en) 2010-11-01 2015-06-30 Atricure, Inc. Robotic toolkit
US8636754B2 (en) 2010-11-11 2014-01-28 Atricure, Inc. Clip applicator
US8942829B2 (en) 2011-01-20 2015-01-27 Medtronic, Inc. Trans-septal lead anchoring
US9265486B2 (en) 2011-08-15 2016-02-23 Atricure, Inc. Surgical device
US9282973B2 (en) 2012-01-20 2016-03-15 Atricure, Inc. Clip deployment tool and associated methods
US9675343B2 (en) * 2013-08-12 2017-06-13 Boston Scientific Scimed, Inc. Wire coil tissue fixation device
US20150045612A1 (en) * 2013-08-12 2015-02-12 Boston Scientific Scimed, Inc. Wire coil tissue fixation device
US20160051811A1 (en) * 2014-08-21 2016-02-25 Biotronik Se & Co. Kg Medical implant with a fixing device
US9827414B2 (en) * 2014-08-21 2017-11-28 Biotronik Se & Co. Kg Medical implant with a fixing device

Also Published As

Publication number Publication date Type
EP1382302B1 (en) 2009-03-25 grant
EP2263559A2 (en) 2010-12-22 application
EP0834282A1 (en) 1998-04-08 application
DE69527990T2 (en) 2003-04-30 grant
ES2183079T3 (en) 2003-03-16 grant
JP2005118590A (en) 2005-05-12 application
EP2047807B1 (en) 2012-10-10 grant
EP0834285B1 (en) 2003-09-10 grant
US6884248B2 (en) 2005-04-26 grant
EP0834282B1 (en) 2002-08-28 grant
US20080097523A1 (en) 2008-04-24 application
JPH10506026A (en) 1998-06-16 application
ES2206651T3 (en) 2004-05-16 grant
DE69531746D1 (en) 2003-10-16 grant
EP0835642A1 (en) 1998-04-15 application
DE69527968T2 (en) 2003-04-30 grant
EP0834283A1 (en) 1998-04-08 application
EP0834284A1 (en) 1998-04-08 application
ES2322989T3 (en) 2009-07-03 grant
ES2183080T3 (en) 2003-03-16 grant
CA2351901A1 (en) 1996-02-15 application
US20040153101A1 (en) 2004-08-05 application
US5964772A (en) 1999-10-12 grant
CA2196905A1 (en) 1996-02-15 application
US6296656B1 (en) 2001-10-02 grant
US8579919B2 (en) 2013-11-12 grant
US5824008A (en) 1998-10-20 grant
DE69527990D1 (en) 2002-10-02 grant
CA2276204A1 (en) 1996-02-15 application
WO1996003925A1 (en) 1996-02-15 application
EP0834284B1 (en) 2002-08-28 grant
DE69527991T2 (en) 2003-04-30 grant
CA2276204C (en) 2001-10-23 grant
JP3691851B2 (en) 2005-09-07 grant
ES2183078T3 (en) 2003-03-16 grant
US5810882A (en) 1998-09-22 grant
DE69527989T2 (en) 2003-04-30 grant
DE69527989D1 (en) 2002-10-02 grant
CA2196905C (en) 1999-09-07 grant
EP0773742B1 (en) 2002-08-28 grant
EP0834283B1 (en) 2002-08-28 grant
US20030135226A1 (en) 2003-07-17 application
ES2182906T3 (en) 2003-03-16 grant
DE69527992T2 (en) 2003-04-30 grant
US6562051B1 (en) 2003-05-13 grant
DE69527991D1 (en) 2002-10-02 grant
DE69531746T2 (en) 2004-04-29 grant
DE69535933D1 (en) 2009-05-07 grant
EP1382302A1 (en) 2004-01-21 application
DE69527968D1 (en) 2002-10-02 grant
EP0834285A1 (en) 1998-04-08 application
EP0773742A1 (en) 1997-05-21 application
CA2351901C (en) 2003-01-28 grant
EP2047807A1 (en) 2009-04-15 application
EP0835642B1 (en) 2002-08-28 grant
EP0835641A1 (en) 1998-04-15 application
DE69527992D1 (en) 2002-10-02 grant
US5582616A (en) 1996-12-10 grant
JP3911276B2 (en) 2007-05-09 grant
ES2183081T3 (en) 2003-03-16 grant
EP2263559A3 (en) 2011-03-16 application

Similar Documents

Publication Publication Date Title
US5643321A (en) Suture anchor assembly and methods
US5911721A (en) Bone fastener
US5814071A (en) Suture anchor assembly and methods
US5564615A (en) Surgical instrument
US5203784A (en) Bioabsorbable tack for joining bodily tissue and apparatus for deploying same
US5593423A (en) Skin fastener
US5662662A (en) Surgical instrument and method
US5573541A (en) Apparatus and method for subcuticular stapling of body tissue
US5478353A (en) Suture tie device system and method for suturing anatomical tissue proximate an opening
US5626587A (en) Method for operating a surgical instrument
US7833234B2 (en) Appliance for storing, distributing and placing surgical fasteners
US7331968B2 (en) Endoscopic clip applier with threaded clip
US5423857A (en) Three piece surgical staple
US5497933A (en) Apparatus and method for applying surgical staples to attach an object to body tissue
US5108422A (en) Skin fastener
US6517542B1 (en) Bone anchoring system
US5928252A (en) Device and method for driving a needle and meniscal repair
US5649963A (en) Suture anchor assembly and methods
US5520702A (en) Method and apparatus for applying a cinch member to the ends of a suture
US8216255B2 (en) Endoscopic clip applier actuator
US20090234387A1 (en) Suture anchor having a suture engaging structure and inserter arrangement
US20080296344A1 (en) Surgical Instrument
US20050273138A1 (en) Devices and methods for anchoring tissue
EP0121362B1 (en) Split-ring type tissue fastener
US4448194A (en) Full stroke compelling mechanism for surgical instrument with drum drive

Legal Events

Date Code Title Description
AS Assignment

Owner name: SHERWOOD SERVICES AG, SWITZERLAND

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:ORIGIN MEDSYSTEMS, INC.;REEL/FRAME:012676/0719

Effective date: 19991222

FPAY Fee payment

Year of fee payment: 4

AS Assignment

Owner name: TYCO HEALTHCARE GROUP LP, CONNECTICUT

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:COVIDIEN AG;REEL/FRAME:022552/0706

Effective date: 20090417

CC Certificate of correction
AS Assignment

Owner name: COVIDIEN AG,SWITZERLAND

Free format text: CHANGE OF NAME;ASSIGNOR:SHERWOOD SERVICES AG;REEL/FRAME:024320/0171

Effective date: 20070309

Owner name: TYCO HEALTHCARE GROUP AG,SWITZERLAND

Free format text: MERGER;ASSIGNOR:COVIDIEN AG;REEL/FRAME:024320/0176

Effective date: 20081215

Owner name: COVIDIEN AG,SWITZERLAND

Free format text: CHANGE OF NAME;ASSIGNOR:TYCO HEALTHCARE GROUP AG;REEL/FRAME:024320/0181

Effective date: 20081215

Owner name: ORIGIN MEDSYSTEMS, INC.,CALIFORNIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:BOLDUC, LEE;KRAMER, THOMAS A.;HODGES, BRIAN A.;AND OTHERS;SIGNING DATES FROM 19941027 TO 19941031;REEL/FRAME:024320/0192

Owner name: TYCO HEALTHCARE GROUP AG, SWITZERLAND

Free format text: MERGER;ASSIGNOR:COVIDIEN AG;REEL/FRAME:024320/0176

Effective date: 20081215

Owner name: ORIGIN MEDSYSTEMS, INC., CALIFORNIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:BOLDUC, LEE;KRAMER, THOMAS A.;HODGES, BRIAN A.;AND OTHERS;SIGNING DATES FROM 19941027 TO 19941031;REEL/FRAME:024320/0192

Owner name: COVIDIEN AG, SWITZERLAND

Free format text: CHANGE OF NAME;ASSIGNOR:SHERWOOD SERVICES AG;REEL/FRAME:024320/0171

Effective date: 20070309

Owner name: COVIDIEN AG, SWITZERLAND

Free format text: CHANGE OF NAME;ASSIGNOR:TYCO HEALTHCARE GROUP AG;REEL/FRAME:024320/0181

Effective date: 20081215

FPAY Fee payment

Year of fee payment: 8

CC Certificate of correction
DC Disclaimer filed
REMI Maintenance fee reminder mailed
LAPS Lapse for failure to pay maintenance fees
FP Expired due to failure to pay maintenance fee

Effective date: 20150513