US20020004651A1 - Drug delivery device provided with a one-way mechanism - Google Patents

Drug delivery device provided with a one-way mechanism Download PDF

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Publication number
US20020004651A1
US20020004651A1 US09/822,162 US82216201A US2002004651A1 US 20020004651 A1 US20020004651 A1 US 20020004651A1 US 82216201 A US82216201 A US 82216201A US 2002004651 A1 US2002004651 A1 US 2002004651A1
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United States
Prior art keywords
piston rod
delivery device
drug delivery
helical spring
axle
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Granted
Application number
US09/822,162
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US6585699B2 (en
Inventor
Henrik Ljunggreen
Jens Poulsen
Soren Aasmul
Lars Christensen
Jens Moller-Jensen
Peter Moller-Jensen
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Novo Nordisk AS
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Novo Nordisk AS
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Priority to DK200000622 priority
Priority to DKPA200000622 priority
Priority to US20151800P priority
Priority to US20780800P priority
Priority to US09/822,162 priority patent/US6585699B2/en
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of US20020004651A1 publication Critical patent/US20020004651A1/en
Assigned to NOVA NORDISK A/S reassignment NOVA NORDISK A/S ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: MOLLER-JENSEN, PETER, MOLLER-JENSEN, JENS, AASMUL, SOREN, CHRISTENSEN, LARS HOFMANN, POULSEN, JENS ULRIK, LJUNGGREEN, HENRIK
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/31518Piston or piston-rod constructions, e.g. connection of piston with piston-rod designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M2005/31588Constructional features or modes of drive mechanisms for piston rods electrically driven
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31543Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/3156Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31593Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Abstract

A drug delivery device comprising a housing (1) with a drug container (2) being provided with delivering means comprising a piston (5) for expelling a drug (4) from the drug container (2). The housing (1) further comprising a displaceable piston rod (6) abutting the piston (5) of the drug container (2) and rotating means being in engagement with the piston rod (6), said rotating means being provided with a one-way mechanism. The one-way mechanism comprises a helical spring (12) wound tightly around an axle (11), one end of said helical spring (12) being fixed in relation to the housing (1), the other end of the helical spring (12) being in a free state.

Description

  • The invention relates to a drug delivery device comprising a housing with a drug container, said drug container having delivering means comprising a piston for expelling a drug from the drug container, said housing further comprising a displaceable piston rod abutting the piston of the drug container, rotating means being in engagement with the piston rod, said rotating means being provided with a one-way mechanism. [0001]
  • The delivery device may be of any type that delivers a liquefied drug to a person as an aerosol spray, an injection or a high-pressure jet. Preferably, however, the delivery device is an injection syringe that may be of a single-use type or a type having an exchangeable drug container or cartridge. [0002]
  • A drug delivery device of this kind is known from U.S. Pat. No. 4,367,739 that discloses a syringe provided with a threaded actuating rod with a piston that is arranged in a container or barrel containing the drug. The actuating rod is provided with a knurled knob at the end opposite the piston, said knurled knob being provided with a one-way mechanism. The one-way mechanism comprises a ratchet lock that may be released by manually disengaging a ratchet tooth from a ratchet wheel. [0003]
  • This type of one-way mechanisms is known in a number of appliances where movement in one direction is allowed while movement in an opposite direction is prevented. The movement may be linear or rotating. [0004]
  • Although widely used, manufacturing of a ratchet lock is relatively complicated since it comprises manufacturing of a ratchet tooth part and a ratchet wheel, each having matching teeth, and mounting each of these parts with cooperating parts of the device in which the ratchet lock is to be used. Finally, the cooperating parts are assembled. [0005]
  • It is an object of the present invention to provide a drug delivery device with a rotatable axle provided with a one-way mechanism that is structurally simpler than the previously known one-way mechanisms of the known devices. [0006]
  • This is achieved by providing the drug delivery device mentioned in the opening paragraph with a one-way mechanism that comprises a helical spring wound tightly around said axle, one end of said helical spring being fixed in relation to the housing, the other end of the helical spring being in a free state. [0007]
  • By arranging the one-way mechanism in this way a very simple and yet reliable one-way mechanism is provided. Further, the one-way mechanism is easy to build into a drug delivery device since it comprises very few parts. [0008]
  • The drug delivery device may be of a single-use type or a type having an exchangeable drug container or cartridge. If the drug delivery device is of the latter type, a release button is provided, said release button being able to displace the free end of the helical spring in a direction of unwinding the helical spring. Thereby the helical spring loses its frictional engagement with the axle and the axle is free to rotate in either direction. [0009]
  • In this way the piston rod can be retracted from the cartridge and the cartridge can be exchanged. [0010]
  • In a preferred embodiment the piston rod is provided with a toothing and is in engagement with a piston rod driving wheel provided with a complementary toothing, said piston rod driving wheel being mounted on said axle. In this embodiment, displacement of the piston rod is provided by rotating the axle, said rotation being provided by any known means, e.g. by a push button in engagement with the axle or by an electric motor. [0011]
  • In order to minimize the size of the drug delivery device the piston rod may be flexible and is positioned partly around the piston rod driving wheel. A guiding face may be provided in the housing, said flexible piston rod being positioned between said guiding face and said piston rod driving wheel.[0012]
  • The invention will be described in detail in the following with reference to the drawings in which [0013]
  • FIG. 1 shows a part of drug delivery device comprising a one-way mechanism according to the invention, and [0014]
  • FIG. 2 shows in enlarged scale the working principle of the one-way mechanism.[0015]
  • In FIG. 1 a part of a drug delivery device according to the invention is shown. The drug delivery device comprises a housing [0016] 1 provided with an accommodation for an exchangeable drug container or cartridge 2. The cartridge 2 is provided with a rubber seal 3 in a first end thereof, said rubber seal 3 being penetratable by a hollow injection needle (not shown) for administration of the drug 4 from the cartridge 2. A displaceable piston 5 is provided in the cartridge 2 for expelling the drug 4.
  • A flexible piston rod [0017] 6 is provided in the housing 1. One end of the flexible piston rod 6 abuts the piston 5 provided in the cartridge 2 and by displacing the flexible piston rod 6 the piston 5 is displaced in the cartridge 2, expelling an amount of the drug 4 from the cartridge 2.
  • The flexible piston rod [0018] 6 is provided with teeth 7 forming a toothing at the inwardly bending side and is in engagement with a piston rod driving wheel 8 provided with teeth 9 that are complementary with the teeth 7. The flexible piston rod 6 is positioned between the piston rod driving wheel 8 and a guiding face 10 of the housing 1.
  • The piston rod driving wheel [0019] 8 is mounted on an axle 11 which is rotatable in an anticlockwise direction (in the direction of the arrow A) as well as in a clockwise direction (in direction of the arrow B).
  • When the axle [0020] 11 is rotated in the direction of the arrow A, the flexible piston rod 6 is displaced downwards in the cartridge 2 displacing the piston 5 and expelling an amount of the drug 4. The axle 11 is rotated in the direction of the arrow A when an amount of the drug 4 is to be administrated to a person.
  • When the axle [0021] 11 is rotated in the direction of the arrow B, the flexible piston rod 6 is displaced upwards in the cartridge 2, optionally totally retracted from the cartridge 2. The axle 11 is rotated in the direction of the arrow B when the cartridge 2 is to be exchanged which requires that the flexible piston rod 6 is removed from the cartridge 2.
  • The rotation of the axle [0022] 11, which controls the displacement of the flexible piston rod 6, is controlled by any known means and is not shown. For instance, the axle 11 may be rotated by mechanical means, such as a push-button provided with a toothed rack that cooperates with a gearwheel provided on the axle 11, or it may be rotated by an electric motor. In the drug delivery device the dose to be administrated may be preset and administration is achieved either by pressing the push-button or by activating the electric motor whichever is the case.
  • In a drug delivery device it is important to prevent dose built-up, i.e. to assure that the amount of drug expelled from the cartridge [0023] 2 corresponds to the set dose when the axle 11 is rotated a preset rotation. Therefore, it is important that the flexible piston rod 6 in normal use is prevented from being displaced backwards in the cartridge 2. If the flexible piston rod 6 is displaced backwards in the cartridge 2 and no longer abuts the piston 5, the next amount of administrated drug will be smaller than prescribed which is undesirable.
  • In order to prevent the flexible piston rod [0024] 6 in being displaced backwards a helical spring 12 is wound tightly around the axle 11. The helical spring 12 has a first end 13 that is fixed to the housing 1 of the drug delivery device and a second end 14 that is in a free state inside the housing 1.
  • The helical spring [0025] 12 is wound tightly around the axle 11 and is therefore frictionally engaged with the axle 11. However, when the axle 11 is rotated anticlockwise in direction of the arrow A, the helical spring 12 loosens due to its free second end 14 and allows the axle 11 to be rotated in this direction.
  • If it is attempted to rotate the axle [0026] 11 clockwise in direction of the arrow B, the helical spring 12 is tightened even more due to the fixed first end 13 and the axle 11 is instantly prevented from being rotated in this direction.
  • The helical spring [0027] 12 being wound tightly around the axle 11 in this way assures that the axle 11 can be rotated in one direction only.
  • However, when the cartridge [0028] 2 is to be exchanged, the flexible piston rod 6 have to be retracted from the cartridge 2, i.e. it has to be drawn backwards by rotating the piston rod driving wheel 8 clockwise. As described above, this rotation is prevented by the helical spring 12 wound around the axle 11. However, by pressing the free end 14 of the helical spring 12 downwards in direction of the arrow C the helical spring 12 loses its frictional engagement with the axle 11 and the axle 11 is allowed to rotate clockwise thereby retracting the flexible piston rod 6 from the cartridge 2. The free end 14 of the helical spring 12 may be pressed downwards by a push-button 15 extending out of the hosing 1.
  • The working principle of the above-described one-way mechanism is shown in FIG. 2 in an enlarged scale. The axle [0029] 11 is rotatable in an anticlockwise direction (arrow A) and in a clockwise direction (arrow B).
  • A helical spring [0030] 12 is wound tightly around the axle 11 thereby being in frictional engagement with the axle 11. A first end 13 of the helical spring 12 is fixed to the housing 1 of the drug delivery device while the other end 14 of the helical spring 12 is in a free state. Rotation of the axle 11 in the direction of the arrow A is allowed since rotation in this direction loosens the helical spring 12 whereby the frictional engagement between the axle 11 and the helical spring 12 decreases.
  • Rotation of the axle [0031] 11 in the direction of the arrow B, however, is prevented since the frictional forces between the axle 11 and the helical spring 12 is increased instantly due to the ever more tightening of the helical spring 12.
  • If the free end [0032] 14 of the helical spring 12 is displaced in the direction of the arrow C, the helical spring is slightly unwound which causes the frictional engagement between the axle 11 and the helical spring 12 to decrease drastically and allows the axle 11 to be rotated clockwise.
  • The helical spring [0033] 12 is pre-wound before it is positioned on the axle 11. The pre-wound helical spring 12 preferably has an inner diameter that is slightly smaller than the outer diameter of the axle 11 when it is not mounted on the axle 11. When mounting the helical spring 12, it is slightly opened causing the inner diameter to increase to a size larger than the outer diameter of the axle 11. Then the helical spring 12 is positioned around the axle and released. When mounted, the helical spring 12 is in frictional engagement with the axle 11.
  • The invention has been described with reference to a preferred embodiment comprising a flexible piston rod [0034] 6. However, the invention may also be applied in other drug delivery devices where a rotating one-way mechanism is applicable.

Claims (7)

1. A drug delivery device comprising a housing (1) with a drug container (2), said drug container (2) having delivering means comprising a piston (5) for expelling a drug (4) from the drug container (2), said housing (1) further comprising a displaceable piston rod (6) abutting the piston (5) of the drug container (2), rotating means being in engagement with the piston rod (6), said rotating means being provided with a one-way mechanism, characterised in that the one-way mechanism comprises a helical spring (12) wound tightly around an axle (11), one end of said helical spring (12) being fixed in relation to the housing (1), the other end of the helical spring (12) being in a free state.
2. A drug delivery device according to claim 1 characterised in that a release button (15) is provided, said release button (15) being able to displace the free end of the helical spring (12) in a direction of unwinding the helical spring (12).
3. A drug delivery device according to claims 1 or 2, characterised in that the piston rod (6) is provided with a toothing (7) and is in engagement with a piston rod driving wheel (8) provided with a complementary toothing (9), said piston rod driving wheel (8) being mounted on said axle (11).
4. A drug delivery device according to claim 3, characterised in that the piston rod (6) is flexible and is positioned partly around the piston rod driving wheel (8).
5. A drug delivery device according to claim 4, characterised in that a guiding face (10) is provided in the housing (1), said flexible piston rod (6) being positioned between said guiding face (10) and said piston rod driving wheel (8).
6. A drug delivery device according to any one of claims 1-5, characterised in that the drug delivery device is provided with an exchangeable drug container (2).
7. A drug delivery device according to any one of claims 1-6, characterised in that the drug delivery device is an injection syringe.
US09/822,162 2000-04-13 2001-03-30 Drug delivery device provided with a one-way mechanism Active 2021-04-05 US6585699B2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DKPA200000622 2000-04-13
DK200000622 2000-04-13
DKPA200000622 2000-04-13
US20151800P true 2000-05-02 2000-05-02
US20780800P true 2000-05-30 2000-05-30
US09/822,162 US6585699B2 (en) 2000-04-13 2001-03-30 Drug delivery device provided with a one-way mechanism

Applications Claiming Priority (1)

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US09/822,162 US6585699B2 (en) 2000-04-13 2001-03-30 Drug delivery device provided with a one-way mechanism

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US20020004651A1 true US20020004651A1 (en) 2002-01-10
US6585699B2 US6585699B2 (en) 2003-07-01

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EP (1) EP1276529B1 (en)
JP (1) JP2003530918A (en)
AT (1) AT330651T (en)
AU (1) AU4829501A (en)
DE (1) DE60120954T2 (en)
WO (1) WO2001078812A1 (en)

Cited By (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050160858A1 (en) * 2002-07-24 2005-07-28 M 2 Medical A/S Shape memory alloy actuator
US20050192561A1 (en) * 2002-07-24 2005-09-01 M 2 Medical A/S Infusion pump system, an infusion pump unit and an infusion pump
US20050245878A1 (en) * 2002-11-05 2005-11-03 M 2 Medical A/S Disposable wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device
US20050251097A1 (en) * 2002-12-23 2005-11-10 M 2 Medical A/S Flexible piston rod
US20050273059A1 (en) * 2002-12-23 2005-12-08 M 2 Medical A/S Disposable, wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device
WO2006105794A1 (en) * 2005-04-06 2006-10-12 M 2 Medical A/S An actuator
US20070073235A1 (en) * 2005-09-26 2007-03-29 Estes Mark C Operating an infusion pump system
US20070073228A1 (en) * 2005-09-26 2007-03-29 Morten Mernoe Dispensing fluid from an infusion pump system
US20070073236A1 (en) * 2005-09-26 2007-03-29 Morten Mernoe Dispensing fluid from an infusion pump system
US20070124002A1 (en) * 2005-11-08 2007-05-31 M2 Medical A/S Method and System for Manual and Autonomous Control of an Infusion Pump
US20070123819A1 (en) * 2005-11-08 2007-05-31 M2 Medical A/S Infusion Pump System
US20070167912A1 (en) * 2005-09-26 2007-07-19 M2 Medical A/S Operating an Infusion Pump System
US20070276329A1 (en) * 2004-01-29 2007-11-29 Morten Mernoe Disposable Medicine Dispensing Device
US20080294109A1 (en) * 2007-05-21 2008-11-27 M2 Medical Group Holdings, Inc. Illumination Instrument for an Infusion Pump
US20080294108A1 (en) * 2007-05-21 2008-11-27 M2 Medical Group Holdings, Inc. Infusion Pump System with Contamination-Resistant Features
US20080294094A1 (en) * 2007-05-21 2008-11-27 M2 Medical Group Holdings, Inc. Occlusion Sensing for an Infusion Pump
US20080294142A1 (en) * 2007-05-21 2008-11-27 M2 Medical Group Holdings, Inc. Removable Controller for an Infusion Pump
US20090067989A1 (en) * 2007-09-06 2009-03-12 M2 Medical Group Holdings, Inc. Occlusion Sensing System for Infusion Pumps
US20090069787A1 (en) * 2007-09-07 2009-03-12 M2 Medical Activity Sensing Techniques for an Infusion Pump System
US20090069746A1 (en) * 2007-09-07 2009-03-12 M2 Medical Group Holdings, Inc. Data Storage for an Infusion Pump System
US7717903B2 (en) 2007-09-06 2010-05-18 M2 Group Holdings, Inc. Operating an infusion pump system
US20100185178A1 (en) * 2009-01-20 2010-07-22 Robert Sharp Injection device
US20100249706A1 (en) * 2009-03-31 2010-09-30 Animas Corporation Novel Drive System for use with an Insulin Delivery Device
US7879026B2 (en) 2007-09-07 2011-02-01 Asante Solutions, Inc. Controlled adjustment of medicine dispensation from an infusion pump device
US8057436B2 (en) 2005-09-26 2011-11-15 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
US8287514B2 (en) 2007-09-07 2012-10-16 Asante Solutions, Inc. Power management techniques for an infusion pump system
US8454557B1 (en) 2012-07-19 2013-06-04 Asante Solutions, Inc. Infusion pump system and method
US8454581B2 (en) 2011-03-16 2013-06-04 Asante Solutions, Inc. Infusion pump systems and methods
US8454562B1 (en) 2012-07-20 2013-06-04 Asante Solutions, Inc. Infusion pump system and method
US8551046B2 (en) 2006-09-18 2013-10-08 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
USD691258S1 (en) 2010-05-27 2013-10-08 Asante Solutions, Inc. Infusion pump
US8585657B2 (en) 2011-06-21 2013-11-19 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
US8808230B2 (en) 2011-09-07 2014-08-19 Asante Solutions, Inc. Occlusion detection for an infusion pump system
US8852152B2 (en) 2011-02-09 2014-10-07 Asante Solutions, Inc. Infusion pump systems and methods
CN104602735A (en) * 2012-07-06 2015-05-06 赛诺菲-安万特德国有限公司 Autoinjector
US20150290392A1 (en) * 2012-08-15 2015-10-15 Sanofi-Aventis Deutschland Gmbh Autoinjector
US20160045668A1 (en) * 2013-04-10 2016-02-18 Sanofi Drive mechanism for a drug delivery device
US20160058988A1 (en) * 2014-08-27 2016-03-03 Acclarent, Inc. Inflator with varying mechanical advantage
US9427523B2 (en) 2012-12-10 2016-08-30 Bigfoot Biomedical, Inc. Infusion pump system and method
US9446187B2 (en) 2013-06-03 2016-09-20 Bigfoot Biomedical, Inc. Infusion pump system and method
US9446186B2 (en) 2013-03-01 2016-09-20 Bigfoot Biomedical, Inc. Operating an infusion pump system
US9457141B2 (en) 2013-06-03 2016-10-04 Bigfoot Biomedical, Inc. Infusion pump system and method
US9561324B2 (en) 2013-07-19 2017-02-07 Bigfoot Biomedical, Inc. Infusion pump system and method
US9629901B2 (en) 2014-07-01 2017-04-25 Bigfoot Biomedical, Inc. Glucagon administration system and methods
US20170173624A1 (en) * 2011-11-01 2017-06-22 Medmix Systems Ag Discharge device for semi-solid materials
US20170246402A1 (en) * 2014-10-07 2017-08-31 Westrock Dispensing Systems, Inc. Indexing dose dispensing device
US9878097B2 (en) 2015-04-29 2018-01-30 Bigfoot Biomedical, Inc. Operating an infusion pump system
USD809134S1 (en) 2016-03-10 2018-01-30 Bigfoot Biomedical, Inc. Infusion pump assembly
US9919096B2 (en) 2014-08-26 2018-03-20 Bigfoot Biomedical, Inc. Infusion pump system and method
US10137246B2 (en) 2014-08-06 2018-11-27 Bigfoot Biomedical, Inc. Infusion pump assembly and method
USD836769S1 (en) 2016-12-12 2018-12-25 Bigfoot Biomedical, Inc. Insulin delivery controller
USD839294S1 (en) 2017-06-16 2019-01-29 Bigfoot Biomedical, Inc. Display screen with graphical user interface for closed-loop medication delivery

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0107601D0 (en) * 2001-03-27 2001-05-16 Dca Design Int Ltd Improvements in and relating to and injection device
US20040039344A1 (en) * 2002-08-22 2004-02-26 Baldwin Brian Eugene System, method and apparatus for administering medical liquids
DE10240166A1 (en) * 2002-08-30 2004-03-18 Disetronic Licensing Ag Injection syringe for dispensing insulin to treat diabetes has piston operated by flexible belt which is moved by manually-operated wheel with teeth which cooperate with catches set to give predetermined dose
CA2543495A1 (en) * 2003-10-28 2005-05-12 Mcneil-Ppc, Inc. Dispensing device for liquid sweetener
WO2005097240A1 (en) * 2004-03-30 2005-10-20 Eli Lilly And Company Medication dispensing apparatus with gear set having drive member accommodating opening
US9028550B2 (en) 2005-09-26 2015-05-12 Coalign Innovations, Inc. Selectively expanding spine cage with enhanced bone graft infusion
US8932355B2 (en) 2008-02-22 2015-01-13 Coalign Innovations, Inc. Spinal implant with expandable fixation
US8992620B2 (en) 2008-12-10 2015-03-31 Coalign Innovations, Inc. Adjustable distraction cage with linked locking mechanisms
US20100145455A1 (en) 2008-12-10 2010-06-10 Innvotec Surgical, Inc. Lockable spinal implant
EP2438938A1 (en) * 2010-10-11 2012-04-11 PharmaSens AG Syringe type pump
US8535268B2 (en) 2010-12-22 2013-09-17 Alcon Research, Ltd. Device for at least one of injection or aspiration
JP6159262B2 (en) * 2011-03-16 2017-07-05 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Drive mechanism for drug delivery device and drug delivery device
EP2836253B1 (en) 2012-04-10 2019-07-03 SHL Medical AG Infusion device
CA2880424A1 (en) * 2012-07-31 2014-02-06 Nipro Healthcare Systems, Llc Device and method for dispensing fluid from an infusion pump
TWI569832B (en) 2013-10-23 2017-02-11 Carebay Europe Ltd Drug delivery device
CA2930577A1 (en) 2013-11-27 2015-06-04 Howmedica Osteonics Corp. Structurally supporting insert for spinal fusion cage
KR101524678B1 (en) * 2014-04-29 2015-06-03 최규동 Short Length Driver for Injection Appartus
WO2017205816A1 (en) 2016-05-26 2017-11-30 Insulet Corporation Single dose drug delivery device
EP3260147A1 (en) * 2016-06-23 2017-12-27 TecPharma Licensing AG A segmented piston rod for a medication delivery device
US10363372B2 (en) 2016-08-12 2019-07-30 Insulet Corporation Plunger for drug delivery device
WO2019118588A1 (en) * 2017-12-13 2019-06-20 Regeneron Pharmaceuticals, Inc. Devices and methods for precision dose delivery

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4917163B1 (en) 1970-01-17 1974-04-27
US4367739A (en) * 1981-04-20 1983-01-11 Leveen Harry H Syringe
US4493704A (en) 1982-11-29 1985-01-15 Oximetrix, Inc. Portable fluid infusion apparatus
FR2596278B2 (en) 1986-03-27 1989-07-13 Micro Mega Sa dental syringe for intra-ligament injections
SE469263B (en) 1991-04-22 1993-06-14 Gudmar Olovson Piston forming part of a syringe which is intended for injection of a liquid
US5300042A (en) 1992-03-02 1994-04-05 Kossoff-Sukel, Inc. Medication dispensing apparatus
DK109293D0 (en) 1993-09-27 1993-09-27 Novo Nordisk As Apparatus
GB9503969D0 (en) 1995-02-28 1995-04-19 Sams Bernard Incrementing mechanism
US5630339A (en) 1995-11-02 1997-05-20 General Motors Corporation Park mechanism for vehicle transmission
HU9904152A3 (en) 1996-07-05 2000-05-29 Novo Nordisk As Flexible piston rod
US6110149A (en) 1996-09-13 2000-08-29 Novo Nordisk A/S Syringe
US6003736A (en) 1997-06-09 1999-12-21 Novo Nordisk A/S Device for controlled dispensing of a dose of a liquid contained in a cartridge
FR2767479B1 (en) 1997-08-22 1999-10-22 Aguettant Lab A drug injection

Cited By (167)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8961462B2 (en) 2002-07-24 2015-02-24 Asante Solutions, Inc. Infusion pump system, an infusion pump unit and an infusion pump
US20050192561A1 (en) * 2002-07-24 2005-09-01 M 2 Medical A/S Infusion pump system, an infusion pump unit and an infusion pump
US8597244B2 (en) 2002-07-24 2013-12-03 Asante Solutions, Inc. Infusion pump system, an infusion pump unit and an infusion pump
US20050160858A1 (en) * 2002-07-24 2005-07-28 M 2 Medical A/S Shape memory alloy actuator
US9463272B2 (en) 2002-07-24 2016-10-11 Bigfoot Biomedical, Inc. Infusion pump system, an infusion pump unit and an infusion pump
US20070201992A1 (en) * 2002-07-24 2007-08-30 M2 Medical A/S Infusion Pump System, an Infusion Pump Unit and an Infusion Pump
US20050245878A1 (en) * 2002-11-05 2005-11-03 M 2 Medical A/S Disposable wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device
US8795233B2 (en) 2002-11-05 2014-08-05 Asante Solutions, Inc. Disposable wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device
US7887511B2 (en) 2002-11-05 2011-02-15 Asante Solutions, Inc. Disposable wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device
US8801655B2 (en) 2002-11-05 2014-08-12 Asante Solutions, Inc. Wearable insulin dispensing device, and a combination of such a device and a programming controller
US9308319B2 (en) 2002-11-05 2016-04-12 Bigfoot Biomedical, Inc. Wearable insulin dispensing device, and a combination of such a device and a programming controller
US9295777B2 (en) 2002-11-05 2016-03-29 Bigfoot Biomedical, Inc. Disposable wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device
US9757512B2 (en) 2002-11-05 2017-09-12 Bigfoot Biomedical, Inc. Wearable insulin dispensing device, and a combination of such a device and a programming controller
US20050273059A1 (en) * 2002-12-23 2005-12-08 M 2 Medical A/S Disposable, wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device
US7785288B2 (en) 2002-12-23 2010-08-31 Asante Solutions, Inc. Disposable, wearable insulin dispensing device, a combination of such a device and a programming controller and a method of controlling the operation of such a device
US20050251097A1 (en) * 2002-12-23 2005-11-10 M 2 Medical A/S Flexible piston rod
US20070203459A1 (en) * 2002-12-23 2007-08-30 M2 Medical A/S Flexible Piston Rod
US20100256565A1 (en) * 2002-12-23 2010-10-07 Asante Solutions, Inc. Disposable, Wearable Insulin Dispensing Device, a Combination of Such a Device and a Programming Controller and a Method of Controlling the Operation of Such a Device
US8469920B2 (en) 2002-12-23 2013-06-25 Asante Solutions, Inc. Wearable insulin dispensing device, and a combination of such a device and a programming controller
US7753879B2 (en) 2004-01-29 2010-07-13 M2 Group Holdings, Inc. Disposable medicine dispensing device
US20070276329A1 (en) * 2004-01-29 2007-11-29 Morten Mernoe Disposable Medicine Dispensing Device
WO2006105794A1 (en) * 2005-04-06 2006-10-12 M 2 Medical A/S An actuator
US8226608B2 (en) 2005-04-06 2012-07-24 Asante Solutions, Inc. Medicine dispensing device
US10105483B2 (en) 2005-04-06 2018-10-23 Bigfoot Biomedical, Inc. Medicine dispensing device
US20070185449A1 (en) * 2005-04-06 2007-08-09 Morten Mernoe Actuator with string drive #1
US8905995B2 (en) 2005-04-06 2014-12-09 Asante Solutions, Inc. Medicine dispensing device
US7713238B2 (en) 2005-04-06 2010-05-11 M2 Group Holdings, Inc. Medicine dispensing device
US8282601B2 (en) 2005-09-26 2012-10-09 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
US7708717B2 (en) 2005-09-26 2010-05-04 M2 Group Holdings, Inc. Operating an infusion pump system
US9814830B2 (en) 2005-09-26 2017-11-14 Bigfoot Biomedical, Inc. Dispensing fluid from an infusion pump system
US9539388B2 (en) 2005-09-26 2017-01-10 Bigfoot Biomedical, Inc. Operating an infusion pump system
US9872957B2 (en) 2005-09-26 2018-01-23 Bigfoot Biomedical, Inc. Operating an infusion pump system
US9517301B2 (en) 2005-09-26 2016-12-13 Bigfoot Biomedical, Inc. Operating an infusion pump system
US7776030B2 (en) 2005-09-26 2010-08-17 Asante Solutions, Inc. Operating an infusion pump system
US10064993B2 (en) 2005-09-26 2018-09-04 Bigfoot Biomedical, Inc. Dispensing fluid from an infusion pump system
US7789859B2 (en) 2005-09-26 2010-09-07 Asante Solutions, Inc. Operating an infusion pump system
US10307536B2 (en) 2005-09-26 2019-06-04 Bigfoot Biomedical, Inc. Operating an infusion pump system
US7794428B2 (en) 2005-09-26 2010-09-14 Asante Solutions, Inc. Operating an infusion pump system
US20080045904A1 (en) * 2005-09-26 2008-02-21 M2 Medical A/S Operating an Infusion Pump System
US9314569B2 (en) 2005-09-26 2016-04-19 Bigfoot Biomedical, Inc. Dispensing fluid from an infusion pump system
US8409142B2 (en) 2005-09-26 2013-04-02 Asante Solutions, Inc. Operating an infusion pump system
US20070167912A1 (en) * 2005-09-26 2007-07-19 M2 Medical A/S Operating an Infusion Pump System
US8105279B2 (en) 2005-09-26 2012-01-31 M2 Group Holdings, Inc. Dispensing fluid from an infusion pump system
US20070167905A1 (en) * 2005-09-26 2007-07-19 M2 Medical A/S Operating an Infusion Pump System
US20070156092A1 (en) * 2005-09-26 2007-07-05 M2 Medical A/S Operating an Infusion Pump System
US7794427B2 (en) 2005-09-26 2010-09-14 Asante Solutions, Inc. Operating an infusion pump system
US20080045931A1 (en) * 2005-09-26 2008-02-21 M2 Medical A/S Operating an Infusion Pump System
US20070073236A1 (en) * 2005-09-26 2007-03-29 Morten Mernoe Dispensing fluid from an infusion pump system
US20070073228A1 (en) * 2005-09-26 2007-03-29 Morten Mernoe Dispensing fluid from an infusion pump system
US7887512B2 (en) 2005-09-26 2011-02-15 Asante Solutions, Inc. Operating an infusion pump system
US20070073235A1 (en) * 2005-09-26 2007-03-29 Estes Mark C Operating an infusion pump system
US7922708B2 (en) 2005-09-26 2011-04-12 Asante Solutions, Inc. Operating an infusion pump system
US8747368B2 (en) 2005-09-26 2014-06-10 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
US8747369B2 (en) 2005-09-26 2014-06-10 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
US7938803B2 (en) 2005-09-26 2011-05-10 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
US20110112504A1 (en) * 2005-09-26 2011-05-12 Asante Solutions, Inc. Operating an Infusion Pump System
US8696633B2 (en) 2005-09-26 2014-04-15 Asante Solutions, Inc. Operating an infusion pump system
US8057436B2 (en) 2005-09-26 2011-11-15 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
US7981084B2 (en) 2005-09-26 2011-07-19 Asante Solutions, Inc. Operating an infusion pump system
US8622966B2 (en) 2005-09-26 2014-01-07 Asante Solutions, Inc. Operating an infusion pump system
US20110190705A1 (en) * 2005-09-26 2011-08-04 Asante Solutions, Inc. Dispensing Fluid from an Infusion Pump System
US20090198186A1 (en) * 2005-09-26 2009-08-06 M2 Group Holdings, Inc. Dispensing Fluid from an Infusion Pump System
US8480623B2 (en) 2005-09-26 2013-07-09 Asante Solutions, Inc. Method for dispensing fluid from an infusion pump system
US8679060B2 (en) 2005-11-08 2014-03-25 Asante Solutions, Inc. Infusion pump system
US20100256564A1 (en) * 2005-11-08 2010-10-07 Asante Solutions, Inc. Infusion Pump System
US8475408B2 (en) 2005-11-08 2013-07-02 Asante Solutions, Inc. Infusion pump system
US20100256563A1 (en) * 2005-11-08 2010-10-07 Asante Solutions, Inc. Infusion Pump System
US8192394B2 (en) 2005-11-08 2012-06-05 Asante Solutions, Inc. Method and system for manual and autonomous control of an infusion pump
US8430847B2 (en) 2005-11-08 2013-04-30 Asante Solutions, Inc. Infusion pump system
US8372039B2 (en) 2005-11-08 2013-02-12 Asante Solutions, Inc. Infusion pump system
US20070123819A1 (en) * 2005-11-08 2007-05-31 M2 Medical A/S Infusion Pump System
US20070124002A1 (en) * 2005-11-08 2007-05-31 M2 Medical A/S Method and System for Manual and Autonomous Control of an Infusion Pump
US20100256598A1 (en) * 2005-11-08 2010-10-07 Asante Solutions, Inc. Infusion Pump System
US8551046B2 (en) 2006-09-18 2013-10-08 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
US20080294142A1 (en) * 2007-05-21 2008-11-27 M2 Medical Group Holdings, Inc. Removable Controller for an Infusion Pump
US9440021B2 (en) 2007-05-21 2016-09-13 Bigfoot Biomedical, Inc. Removable controller for an infusion pump
US8211062B2 (en) 2007-05-21 2012-07-03 Asante Solutions, Inc. Illumination instrument for an infusion pump
US8454575B2 (en) 2007-05-21 2013-06-04 Asante Solutions, Inc. Illumination instrument for an infusion pump
US20080294108A1 (en) * 2007-05-21 2008-11-27 M2 Medical Group Holdings, Inc. Infusion Pump System with Contamination-Resistant Features
US20080294109A1 (en) * 2007-05-21 2008-11-27 M2 Medical Group Holdings, Inc. Illumination Instrument for an Infusion Pump
US7794426B2 (en) 2007-05-21 2010-09-14 Asante Solutions, Inc. Infusion pump system with contamination-resistant features
US8152765B2 (en) 2007-05-21 2012-04-10 Asante Solutions, Inc. Infusion pump system with contamination-resistant features
US9474854B2 (en) 2007-05-21 2016-10-25 Bigfoot Biomedical, Inc. Occlusion sensing for an infusion pump
US9480793B2 (en) 2007-05-21 2016-11-01 Bigfoot Biomedical, Inc. Occlusion sensing for an infusion pump
US7833196B2 (en) 2007-05-21 2010-11-16 Asante Solutions, Inc. Illumination instrument for an infusion pump
US20110021992A1 (en) * 2007-05-21 2011-01-27 Asante Solutions, Inc. Illumination Instrument for an Infusion Pump
US8852141B2 (en) 2007-05-21 2014-10-07 Asante Solutions, Inc. Occlusion sensing for an infusion pump
US7892199B2 (en) 2007-05-21 2011-02-22 Asante Solutions, Inc. Occlusion sensing for an infusion pump
US20080294094A1 (en) * 2007-05-21 2008-11-27 M2 Medical Group Holdings, Inc. Occlusion Sensing for an Infusion Pump
US8834420B2 (en) 2007-05-21 2014-09-16 Asante Solutions, Inc. Illumination instrument for an infusion pump
US7981102B2 (en) 2007-05-21 2011-07-19 Asante Solutions, Inc. Removable controller for an infusion pump
US9962482B2 (en) 2007-05-21 2018-05-08 Bigfoot Biomedical, Inc. Removable controller for an infusion pump
US8641673B2 (en) 2007-05-21 2014-02-04 Asante Solutions, Inc. Removable controller for an infusion pump
US8647302B2 (en) 2007-05-21 2014-02-11 Asante Solutions, Inc. Infusion pump system with contamination-resistant features
US20110118662A1 (en) * 2007-05-21 2011-05-19 Asante Solutions, Inc. Occlusion Sensing for an Infusion Pump
US9717849B2 (en) 2007-05-21 2017-08-01 Bigfoot Biomedical, Inc. Occlusion sensing for an infusion pump
US20090067989A1 (en) * 2007-09-06 2009-03-12 M2 Medical Group Holdings, Inc. Occlusion Sensing System for Infusion Pumps
US7828528B2 (en) 2007-09-06 2010-11-09 Asante Solutions, Inc. Occlusion sensing system for infusion pumps
US8109921B2 (en) 2007-09-06 2012-02-07 Asante Solutions, Inc. Operating a portable medical device
US7717903B2 (en) 2007-09-06 2010-05-18 M2 Group Holdings, Inc. Operating an infusion pump system
US10226572B2 (en) 2007-09-06 2019-03-12 Bigfoot Biomedical, Inc. Operating a portable medical device
US8870853B2 (en) 2007-09-06 2014-10-28 Asante Solutions, Inc. Operating a portable medical device
US9381302B2 (en) 2007-09-07 2016-07-05 Bigfoot Biomedical, Inc. User profile backup system for an infusion pump device
US8622990B2 (en) 2007-09-07 2014-01-07 Asante Solutions, Inc. Activity sensing techniques for an infusion pump system
US20090069746A1 (en) * 2007-09-07 2009-03-12 M2 Medical Group Holdings, Inc. Data Storage for an Infusion Pump System
US10117993B2 (en) 2007-09-07 2018-11-06 Bigfoot Biomedical, Inc. Activity sensing techniques for an infusion pump system
US7879026B2 (en) 2007-09-07 2011-02-01 Asante Solutions, Inc. Controlled adjustment of medicine dispensation from an infusion pump device
US8894628B2 (en) 2007-09-07 2014-11-25 Asante Solutions, Inc. Activity sensing techniques for an infusion pump system
US9415158B2 (en) 2007-09-07 2016-08-16 Bigfoot Biomedical, Inc. Power management techniques for an infusion pump system
US8551070B2 (en) 2007-09-07 2013-10-08 Asante Solutions, Inc. User profile backup system for an infusion pump device
US8328754B2 (en) 2007-09-07 2012-12-11 Asante Solutions, Inc. Activity sensing techniques for an infusion pump system
US7935076B2 (en) 2007-09-07 2011-05-03 Asante Solutions, Inc. Activity sensing techniques for an infusion pump system
US9522232B2 (en) 2007-09-07 2016-12-20 Bigfoot Biomedical, Inc. Data storage for an infusion pump system
US8032226B2 (en) 2007-09-07 2011-10-04 Asante Solutions, Inc. User profile backup system for an infusion pump device
US9254362B2 (en) 2007-09-07 2016-02-09 Bigfoot Biomedical, Inc. Activity sensing techniques for an infusion pump system
US7935105B2 (en) 2007-09-07 2011-05-03 Asante Solutions, Inc. Data storage for an infusion pump system
US10226575B2 (en) 2007-09-07 2019-03-12 Bigfoot Biomedical, Inc. Power management techniques for an infusion pump system
US8211093B2 (en) 2007-09-07 2012-07-03 Asante Solutions, Inc. Data storage for an infusion pump system
US20110202004A1 (en) * 2007-09-07 2011-08-18 Asante Solutions, Inc. Data Storage for an Infusion Pump System
US8287514B2 (en) 2007-09-07 2012-10-16 Asante Solutions, Inc. Power management techniques for an infusion pump system
US8685002B2 (en) 2007-09-07 2014-04-01 Asante Solutions, Inc. Data storage for an infusion pump system
US20110130716A1 (en) * 2007-09-07 2011-06-02 Asante Solutions, Inc. Activity Sensing Techniques for an Infusion Pump System
US20090069787A1 (en) * 2007-09-07 2009-03-12 M2 Medical Activity Sensing Techniques for an Infusion Pump System
US8734402B2 (en) 2009-01-20 2014-05-27 Future Injection Technologies Limited Injection device
US20100185178A1 (en) * 2009-01-20 2010-07-22 Robert Sharp Injection device
US20100249706A1 (en) * 2009-03-31 2010-09-30 Animas Corporation Novel Drive System for use with an Insulin Delivery Device
US8517991B2 (en) * 2009-03-31 2013-08-27 Animas Corporation Drive system for use with an insulin delivery device
USD691258S1 (en) 2010-05-27 2013-10-08 Asante Solutions, Inc. Infusion pump
US9259529B2 (en) 2011-02-09 2016-02-16 Bigfoot Biomedical, Inc. Infusion pump systems and methods
US8852152B2 (en) 2011-02-09 2014-10-07 Asante Solutions, Inc. Infusion pump systems and methods
US9132234B2 (en) 2011-03-16 2015-09-15 Bigfoot Biomedical, Inc. Infusion pump systems and methods
US8454581B2 (en) 2011-03-16 2013-06-04 Asante Solutions, Inc. Infusion pump systems and methods
US9801997B2 (en) 2011-03-16 2017-10-31 Bigfoot Biomedical, Inc. Infusion pump systems and methods
US8585657B2 (en) 2011-06-21 2013-11-19 Asante Solutions, Inc. Dispensing fluid from an infusion pump system
US9610404B2 (en) 2011-09-07 2017-04-04 Bigfoot Biomedical, Inc. Method for occlusion detection for an infusion pump system
US8808230B2 (en) 2011-09-07 2014-08-19 Asante Solutions, Inc. Occlusion detection for an infusion pump system
US9981283B2 (en) * 2011-11-01 2018-05-29 Medmix Systems Ag Discharge device for paste-like materials with separately formed adapter for connecting a container to a base body
US20170173624A1 (en) * 2011-11-01 2017-06-22 Medmix Systems Ag Discharge device for semi-solid materials
CN104602735A (en) * 2012-07-06 2015-05-06 赛诺菲-安万特德国有限公司 Autoinjector
US9545476B2 (en) 2012-07-19 2017-01-17 Bigfoot Biomedical, Inc. Infusion pump system and method
US8945044B2 (en) 2012-07-19 2015-02-03 Asante Solutions, Inc. Infusion pump system and method
US8454557B1 (en) 2012-07-19 2013-06-04 Asante Solutions, Inc. Infusion pump system and method
US9517300B2 (en) 2012-07-20 2016-12-13 Bigfoot Biomedical, Inc. Pump system and method
US8454562B1 (en) 2012-07-20 2013-06-04 Asante Solutions, Inc. Infusion pump system and method
US20150290392A1 (en) * 2012-08-15 2015-10-15 Sanofi-Aventis Deutschland Gmbh Autoinjector
US10413667B2 (en) * 2012-08-15 2019-09-17 Sanofi-Aventis Deutschland Gmbh Autoinjector
US10232108B2 (en) 2012-12-10 2019-03-19 Bigfoot Biomedical, Inc. Infusion pump system and method
US9427523B2 (en) 2012-12-10 2016-08-30 Bigfoot Biomedical, Inc. Infusion pump system and method
US9446186B2 (en) 2013-03-01 2016-09-20 Bigfoot Biomedical, Inc. Operating an infusion pump system
US10099015B2 (en) * 2013-04-10 2018-10-16 Sanofi Drive mechanism for a drug delivery device
US20160045668A1 (en) * 2013-04-10 2016-02-18 Sanofi Drive mechanism for a drug delivery device
US9446187B2 (en) 2013-06-03 2016-09-20 Bigfoot Biomedical, Inc. Infusion pump system and method
US9956339B2 (en) 2013-06-03 2018-05-01 Bigfoot Biomedical, Inc. Infusion pump system and method
US9457141B2 (en) 2013-06-03 2016-10-04 Bigfoot Biomedical, Inc. Infusion pump system and method
US9561324B2 (en) 2013-07-19 2017-02-07 Bigfoot Biomedical, Inc. Infusion pump system and method
US10207047B2 (en) 2013-07-19 2019-02-19 Bigfoot Biomedical, Inc. Infusion pump system and method
US9629901B2 (en) 2014-07-01 2017-04-25 Bigfoot Biomedical, Inc. Glucagon administration system and methods
US10137246B2 (en) 2014-08-06 2018-11-27 Bigfoot Biomedical, Inc. Infusion pump assembly and method
US9919096B2 (en) 2014-08-26 2018-03-20 Bigfoot Biomedical, Inc. Infusion pump system and method
US10130799B2 (en) * 2014-08-27 2018-11-20 Acclarent, Inc. Inflator with varying mechanical advantage
US20160058988A1 (en) * 2014-08-27 2016-03-03 Acclarent, Inc. Inflator with varying mechanical advantage
US20170246402A1 (en) * 2014-10-07 2017-08-31 Westrock Dispensing Systems, Inc. Indexing dose dispensing device
US9878097B2 (en) 2015-04-29 2018-01-30 Bigfoot Biomedical, Inc. Operating an infusion pump system
USD809134S1 (en) 2016-03-10 2018-01-30 Bigfoot Biomedical, Inc. Infusion pump assembly
USD836769S1 (en) 2016-12-12 2018-12-25 Bigfoot Biomedical, Inc. Insulin delivery controller
USD839294S1 (en) 2017-06-16 2019-01-29 Bigfoot Biomedical, Inc. Display screen with graphical user interface for closed-loop medication delivery
USD852837S1 (en) 2017-06-16 2019-07-02 Bigfoot Biomedical, Inc. Display screen with graphical user interface for closed-loop medication delivery

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