US1656784A - Medicament for treating diseases of the stomach and intestines - Google Patents
Medicament for treating diseases of the stomach and intestines Download PDFInfo
- Publication number
- US1656784A US1656784A US96943A US9694326A US1656784A US 1656784 A US1656784 A US 1656784A US 96943 A US96943 A US 96943A US 9694326 A US9694326 A US 9694326A US 1656784 A US1656784 A US 1656784A
- Authority
- US
- United States
- Prior art keywords
- medicament
- stomach
- intestines
- treating diseases
- atropine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
Definitions
- My invention relates to medicaments for treating diseases of the stomach and intestines and has for its object to provide an improved medicament for this purpose.
- a medicament which contains methylatropine-bromide mixed with substances having an anaesthetic action, for example '.p-amidobenzoic-acid-etliyl-estcr and oil of peppermint, which medicament. is adapted. not only for use in treating diseases of the stomach and intestines, but also for use in removing trouble in the region of the vegetative nervous system.
- Methyl-atropine-bromide exercises a soothing action wh1ch is increased by the addition of substances having an anzesthetic action. It is very important that the said atropine preparation is characterized in that, on the one hand, it is decidedly less poisonous than the other atropine derivatives and especially so than atropinum sulfuricum which is most frequently used in medicine, and further in that when it is applied in the customary doses usual all those disagreeable poisonous effects which are connected with the use of the sulphate atropine, such as e. g. accommodation troubles, severe dryness in the neck, thirst, are entirely absent.
- the anaesthetizing components in the combination are so selected as to dose and chemical composition that, as my tests have shown, no inflammation of the sensitive mucous membrane is caused, and poisoning eftects are quite impossible with the doses proposed by me.
- the local anaesthetic action is made up of three components: firstly methyl-atropine-bromide, as is also the case with the sulphate atropine, exerts a slight local anaesthetic action quite apart from the fact that central anal esic effects are especially peculiar to it. econdly the intended local anaesthesia is produced especially by the almost insoluble p-amido-benzoic-acid- Application fied March 24, 1926. Serial No. 96,943.
- a medicament for the purpose described, comprisin methyl-atropine-bromide mixed with p-ami o-benzoic-acid-ethyl-ester and oil of peppermint.
- a medicament in tablet form for the purpose described, comprising 0.5 milligram methylatropine-bromide, 0.1 gr. amidobenzoicacid-ethyl-ester, drop of oil of peppermint and a neutral filling material.
Description
it "g'". u i (it Jana UNITED STATES PATENT oFFIcE.
AUGUST FISCHER, OF BERN, SWITZERLAND.
No Drawing.
My invention relates to medicaments for treating diseases of the stomach and intestines and has for its object to provide an improved medicament for this purpose.
According to this invention there is pro vided a medicament which contains methylatropine-bromide mixed with substances having an anaesthetic action, for example '.p-amidobenzoic-acid-etliyl-estcr and oil of peppermint, which medicament. is adapted. not only for use in treating diseases of the stomach and intestines, but also for use in removing trouble in the region of the vegetative nervous system.
Methyl-atropine-bromide exercises a soothing action wh1ch is increased by the addition of substances having an anzesthetic action. It is very important that the said atropine preparation is characterized in that, on the one hand, it is decidedly less poisonous than the other atropine derivatives and especially so than atropinum sulfuricum which is most frequently used in medicine, and further in that when it is applied in the customary doses usual all those disagreeable poisonous effects which are connected with the use of the sulphate atropine, such as e. g. accommodation troubles, severe dryness in the neck, thirst, are entirely absent.
The anaesthetizing components in the combination are so selected as to dose and chemical composition that, as my tests have shown, no inflammation of the sensitive mucous membrane is caused, and poisoning eftects are quite impossible with the doses proposed by me. The local anaesthetic action is made up of three components: firstly methyl-atropine-bromide, as is also the case with the sulphate atropine, exerts a slight local anaesthetic action quite apart from the fact that central anal esic effects are especially peculiar to it. econdly the intended local anaesthesia is produced especially by the almost insoluble p-amido-benzoic-acid- Application fied March 24, 1926. Serial No. 96,943.
ethylnster. To these actions there is added, thirdly, the slightly anaesthetizing, hyperzemizing and simultaneously disinfecting eitect of oil of peppermint.
These three substances are made up in tablet form together with the usual neutral filling materials, and the tablets are so dosed that each contains as effective constituent parts 0.5 milligram atropinum-methyl-bromatum, 0.1 gr. amido benzoic-acid-ethylester, and drop of oil of eppermint.
These tablets can be used reliably and in many ways with respect to alleviating pain, limiting secretion, diminishing hypertonus and hyperperistaltic of the stomach, the
sovereign spasmolytic action on the stomach intestines and gall-bladder and other organs with smooth muscles, and the stimulating action on the peristalitic of the intestinal canal, and their action makes the same an exceedingly valuable medicament which is certainly superior to atropinun'i sulfuricum in the therapy of abdominal diseases, particularly because the new medicament has been found to be considerably less poisonous than the sulphate atropine and it is quite free from disagreeable accompanying effects when used 1n doses that come into question therapeutically.
I claim:
1. As a new article of manufacture, a medicament, for the purpose described, comprisin methyl-atropine-bromide mixed with p-ami o-benzoic-acid-ethyl-ester and oil of peppermint.
2. As a new article of manufacture, a medicament in tablet form, for the purpose described, comprising 0.5 milligram methylatropine-bromide, 0.1 gr. amidobenzoicacid-ethyl-ester, drop of oil of peppermint and a neutral filling material.
Signed at Bern, this 10th day of March, 1926.
DR. MED. AUGUST FISCHER.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US96943A US1656784A (en) | 1926-03-24 | 1926-03-24 | Medicament for treating diseases of the stomach and intestines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US96943A US1656784A (en) | 1926-03-24 | 1926-03-24 | Medicament for treating diseases of the stomach and intestines |
Publications (1)
Publication Number | Publication Date |
---|---|
US1656784A true US1656784A (en) | 1928-01-17 |
Family
ID=22259857
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US96943A Expired - Lifetime US1656784A (en) | 1926-03-24 | 1926-03-24 | Medicament for treating diseases of the stomach and intestines |
Country Status (1)
Country | Link |
---|---|
US (1) | US1656784A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2628185A (en) * | 1949-04-01 | 1953-02-10 | Lewenstein Mozes Juda | Analgesic compounds and compositions |
US2830930A (en) * | 1955-08-08 | 1958-04-15 | Jr Allen M Olinger | Parenteral dental local anesthetic solutions containing an alkantheline |
-
1926
- 1926-03-24 US US96943A patent/US1656784A/en not_active Expired - Lifetime
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2628185A (en) * | 1949-04-01 | 1953-02-10 | Lewenstein Mozes Juda | Analgesic compounds and compositions |
US2830930A (en) * | 1955-08-08 | 1958-04-15 | Jr Allen M Olinger | Parenteral dental local anesthetic solutions containing an alkantheline |
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