Connect public, paid and private patent data with Google Patents Public Datasets

Improvement in putting up medicines

Download PDF

Info

Publication number
US108034A
US108034A US108034DA US108034A US 108034 A US108034 A US 108034A US 108034D A US108034D A US 108034DA US 108034 A US108034 A US 108034A
Authority
US
Grant status
Grant
Patent type
Prior art keywords
medicines
slate
up
tablets
doses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Publication date
Grant date

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Description

in the several figures.

FREDERIG KRAUS, or CINCINNATI, onIo;

IMPROVEMENT llN PUTTING UP MEDICINES.

Specification forming part of LettersPatent No. 108,034, dated October 4, 1870.

To all whom iii may concern.-

Be it known that I, FREDERIG KRAUS, of

Cincinnati, in the county of Hamilton and companying drawing, which makes part of this specification, and in which Figures 1 and2represent the slates on which my improved medicines are" prepared, and Figs. 3 and 4 represent specimens of my improved-medicine.

Like letters of reference indicate like parts The nature of my invention consists in putting up medicines in gelatinous tablets divided by indented lines into parts of equal size, each partbeing made to contain the desired dose of medicine, so that each tablet contains any desired number of equal doses; also,

. in the slates on which these medicines are prepared;

My invention has for its object the putting up of medicines in such a way that they can be taken with the greatest ease by the most delicate patients, while the doses are made equal with the most absolute certainty. Their bulk is so reduced that any quantity of various medicines may be carried by physicians withoutinconvenience, who thus may at once dispense the medicines they prescribe.

Druggists who preparemedicines in this manner in various doses are saved a great deal of trouble in compounding prescriptions, and the medicines can be safely kept without danger of spoiling.

I compound my improved medicines in tablets containing a large number of doses, and out these up into smaller tablets containing the number of doses prescribed.

Any kind of medicine which can be dissolved can be put up in this way; and I will now proceed to describe the preparation of sulphuric morphine as an'example.

I dissolve eighty grains of the finest, purest, and whitest gelatine in eight ounces distilled water at a proper degree of heat, preferably 63 Celsius. of morphine, thoroughly mixed in thirty-six drops of chemically-pure glycerine. Stir'the whole carefully, and then pour it evenly over the slate. I

This slate may be of any desired size; but I prefer making it siX inches by twelve and one-half, sothat when the same is perfectly polished and divided into squares of one-half inch, by means of double parallel lines engraved into the slate to the depth of about half a line, the slate will contain three hundred squares of perfectly equal size. In Fig. l I have shown this slatein its frameA, which may be constructed of wood, metal, or any other suitable material, and extends above the surface of the slate.

- The slate is made detachable from the frame,

so that different slates, being divided into larger or smaller squares, maybe used, accorddust, and allow the solution to dry at a temperature of about 40 to 45 Celsius. The

gelatinous tablet thus prepared easily loosens from the slate, and is then out between the parallel lines which have been formed on the same by the indented lines on the slate into smaller tablets of twelve or any other. desired number of squares, each square containing exactly one-fourth of a grain of sulphuric morphine, as shown in Fig. 3.

In Fig. 4 I have shown a tablet which is intended for medicines which are applied to the eyes, or other very tender parts of the body, in very small dosesas, for instance,

sulphuric atropine, which isapplied to the that the whole dose can be applied directly to the diseased portion of the eye, on' which it remains by reason of its gelatmouscharacter,

To this I add seventy-five grains and it cannot, on account of its fineness, irritate the most delicate part.

In traveling these medicine-tablets can be easily carried, and any person knowing the dose required can purchase these medicines and take them with perfect safety.

Having thus described my invention, what I claim as new, and desire to secure by Letters Patent, is

1. The method of preparing medicines in the manner substantially herein described.

2. Medicines or drugs put up in gelatinous tablets, which are divided into equal doses,in the manner substantially as herein described.

3. lhe slates shown in Figs. 1 and 2, for preparing gelatinous medicine tablets, substantially as herein described.

FBEDERIO KRAUS.

Vitnesses:

J. JAUMANN, J. A. KEY.

US108034A Improvement in putting up medicines Expired - Lifetime US108034A (en)

Publications (1)

Publication Number Publication Date
US108034A true US108034A (en) 1870-10-04

Family

ID=2177508

Family Applications (1)

Application Number Title Priority Date Filing Date
US108034A Expired - Lifetime US108034A (en) Improvement in putting up medicines

Country Status (1)

Country Link
US (1) US108034A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3863633A (en) * 1971-06-04 1975-02-04 Pharmacia Ab Composition containing a substance showing a topical effect on the eye, and a method of preparing the same
US4179497A (en) * 1973-12-17 1979-12-18 Merck & Co., Inc. Solid state ophthalmic medication
US4265875A (en) * 1976-07-23 1981-05-05 Inveresk Research International Controlled release suppositories

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3863633A (en) * 1971-06-04 1975-02-04 Pharmacia Ab Composition containing a substance showing a topical effect on the eye, and a method of preparing the same
US4179497A (en) * 1973-12-17 1979-12-18 Merck & Co., Inc. Solid state ophthalmic medication
US4265875A (en) * 1976-07-23 1981-05-05 Inveresk Research International Controlled release suppositories
US4292300A (en) * 1976-07-23 1981-09-29 Inveresk Research International Controlled release suppositories

Similar Documents

Publication Publication Date Title
US3382150A (en) Spray-dried coated organopolysiloxane oral pharmaceutical or veterinary composition
Winokur et al. The Iowa 500: follow-up of 225 depressives
US132275A (en) Improvement in medical compounds
Guy et al. The possibility of total elimination of retrolental fibroplasia by oxygen restriction
Lesser et al. Effect of testosterone propionate on the prostate gland of patients over 45
World Health Organization The international pharmacopoeia
Krakowka et al. Local treatment of aspergilloma of the lung with a paste containing nystatin or amphotericin B
US2853421A (en) Gelatin pan coating
US1815902A (en) Device for administering medicaments
Boyd The use and abuse of phenacetin
US2971889A (en) Press coated enteric tablets and process for preparing them
Hetzel et al. Cimetidine interaction with warfarin
Herrmann et al. Digitalis poisoning
Burchiel et al. A mixed functional microadenoma and ganglioneuroma of the pituitary fossa: case report
US93300A (en) Improved eye-sirup
Godal et al. Aspirin and bleeding-time
US1701811A (en) Capsule
Goldwasser et al. Concomitant treatment of neuroleptic malignant syndrome and psychosis.
Rosenheim General Introduction
Wilken et al. Cellulose acetate succinate as an enteric coating for some compressed tablets
US109677A (en) Improvement in confectionery for druggists
US1222584A (en) Self-rising-flour-mixing machine.
Cowan Multiple epiphysial dysplasia
Greenberg et al. Outbreak of sodium nitrite poisoning
US2306120A (en) Method of molding and product resulting therefrom