US10722134B2 - Gel-assisted electroencephalogram sensor electrode - Google Patents
Gel-assisted electroencephalogram sensor electrode Download PDFInfo
- Publication number
- US10722134B2 US10722134B2 US15/855,904 US201715855904A US10722134B2 US 10722134 B2 US10722134 B2 US 10722134B2 US 201715855904 A US201715855904 A US 201715855904A US 10722134 B2 US10722134 B2 US 10722134B2
- Authority
- US
- United States
- Prior art keywords
- eeg
- gel
- user
- sensor
- electrically
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related, expires
Links
Images
Classifications
-
- A61B5/0478—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/683—Means for maintaining contact with the body
- A61B5/6832—Means for maintaining contact with the body using adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
-
- A61B5/04842—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
- A61B5/377—Electroencephalography [EEG] using evoked responses
- A61B5/378—Visual stimuli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6814—Head
Definitions
- This specification relates generally to electroencephalogram (EEG) systems and more specifically to EEG systems and methods for using sensor electrodes with electrically conductive gel.
- EEG electroencephalogram
- EEG electroencephalogram
- EEG researchers have investigated brain activity using the event-related potential (ERP) technique, in which a large number of experimental trials are time-locked and then averaged together, allowing the investigator to probe sensory, perceptual, and cognitive processing with millisecond precision.
- ERP event-related potential
- EEG experiments are typically administered in a laboratory environment by one or more trained technicians. EEG administration often involves careful application of multiple sensor electrodes to a person's scalp, acquiring EEG signals using specialized and complex equipment, and offline EEG signal analysis by a trained individual.
- This specification describes technologies for EEG signal processing in general, and specifically to systems and methods for using sensor electrodes with electrically conducting gel to facilitate continuous collection of brain activity data.
- These technologies generally involve an EEG system that is portable with easy to apply sensors.
- the sensors can automatically and/or continuously dispense conductive gel to a user's skin, e.g., on the user's scalp, in order to facilitate electrical contact between the sensor and the user's scalp, and thereby enhance collection of brain activity data.
- the sensors can also have a release mechanism that is configured to perform a release action to reduce the adhesion of the conductive gel and release the sensors that are bonded to the user's skin, e.g., on the user's scalp.
- an example EEG system which is able to prompt, acquire, and process EEG signals in real time, and determine actions or behaviors desired by a user based on the EEG signals, can do so with reliable electrical contact of the sensor to the user's skin.
- the sensors can be easily applied, easy removal, and minimal cleanup.
- This specification also generally describes an EEG system, integrated with machine learning models, that provides cleaned EEG signals and can implement actions chosen by a user based on the EEG signals alone. For example, a user may be looking at a menu and create brain signals to select a menu item using only brain activity.
- the EEG system can receive EEG signals from the user's brain and determine which menu item the user intends to select based on the EEG signals.
- the EEG system uses the EEG signals as input to machine learning models and generates output including EEG signals and the user's selection.
- the invention features an electroencephalogram sensor.
- inventions of this aspect include corresponding computer systems, apparatus, and computer programs recorded on one or more computer storage devices, each configured to perform the actions of the methods.
- a system of one or more computers to be configured to perform particular operations or actions means that the system has installed on it software, firmware, hardware, or a combination of them that in operation cause the system to perform the operations or actions.
- one or more computer programs to be configured to perform particular operations or actions means that the one or more programs include instructions that, when executed by data processing apparatus, cause the apparatus to perform the operations or actions.
- An example method for analyzing electroencephalogram (EEG) signals includes: presenting information associated with two or more options to a user; receiving EEG signals from a sensor coupled to the user contemporaneously to the user receiving the information associated with the two or more options; processing the EEG signals in real time to determine which one of the options was selected by the user; and in response to determining which one of the options was selected by the user, selecting an action from one or more possible actions associated with the information presented to the user; and generating an output associated with the selected action.
- EEG electroencephalogram
- the generated output may include control signal for an electronic device.
- the steps of presenting, processing, and generating may be part of a closed-loop feedback system through which the user controls the electronic device.
- the information may be presented to the user using the electronic device.
- the electronic device may be selected from the group consisting of a networked device, a personal computer, a tablet computer, a mobile phone, and a wearable computer.
- information may be presented visibly or audibly to the user.
- the information may be presented based on an object detected in the user's environment.
- the object may be detected based using machine vision.
- processing the EEG signals may include cleaning the EEG signals in real time. Cleaning the EEG signals may include increasing a signal-to-noise ratio of the EEG signals.
- the EEG signals may be cleaned according to a machine learning model.
- the machine learning model may be a neural network or another artificial intelligence architecture.
- Processing the EEG signals may include performing mathematical transformations on the EEG signals in real time after cleaning the EEG signals to determine which of the options was selected by the user.
- the mathematical transformations may be performed according to a machine learning model.
- the machine learning model may be a neural network or other artificial intelligence architecture.
- the machine learning model may map a time series of values corresponding to an amplitude or change in amplitude of the EEG signal to an output variable corresponding to one of the options based on a mapping function.
- the mapping function may be determined by training the machine learning model.
- generating an output may include presenting the user with additional information associated with the selected action.
- the additional information associated with the selected action may be information associated with two or more further options.
- generating an output may include sending instructions over a network in communication with a processor used to process the EEG signals.
- An example electroencephalogram system includes: a plurality of sensors for detecting electrical activity in a user's brain; a user interface configured to present information to the user; and a data processing apparatus in communication with the plurality of sensors and the user interface, the data processing apparatus comprising at least one computer processor and being programmed, during operation of the EEG system, to cause the EEG system to: prompt the user to select from two or more options; receive EEG signals from the plurality of sensors contemporaneously to the user receiving the information about the options; process the EEG signals in real time to determine which one of the options was selected by the user; in response to determining which one of the options was selected by the user, select an action from one or more possible actions associated with the information presented to the user; and generate an output associated with the selected action.
- the user interface is a component of an electronic device and the plurality of sensors and data processing apparatus are part of a closed-loop feedback system through which the user controls the electronic device.
- the electronic device may be selected from the group consisting of a networked device, a personal computer, a tablet computer, a mobile phone, and a wearable computer.
- the user interface may comprise an electronic display.
- the data processing apparatus may be programmed to process the EEG signals by cleaning the EEG signals in real time.
- the data processing apparatus may be programmed to process the EEG signals by performing mathematical transformations on the EEG signals in real time after cleaning the EEG signals to determine which one of the options was selected by the user.
- the mathematical transformations may be performed according to a machine learning model.
- At least one computer processor may perform both the EEG signal cleaning and the mathematical transformations.
- a bioamplifier may include the data processing apparatus.
- the bioamplifier may include an analogue-to-digital converter arranged to receive the EEG signals from the plurality of sensors and convert the EEG signals from analogue signals to digital signals.
- the bioamplifier may further include an amplifier arranged to receive the EEG signals from the analogue-to-digital converter and amplify the received EEG signals.
- the bioamplifier may include a housing containing the data processing apparatus and a power source.
- the user interface may include an electronic display.
- the user interface may include a camera.
- the system may include a networked computing device in communication with the user interface.
- the system may include a mobile device, wherein the user interface and data processing apparatus are part of the mobile device.
- the plurality of sensors include an active sensor and a reference sensor.
- the plurality of sensors may be dry sensors.
- the system may include a wireless transceiver connecting the plurality of sensors with the data processing apparatus.
- generating the output includes providing one or more instructions to a computer program on a computer device in communication with the data processing apparatus.
- An example bioamplifier for analyzing electroencephalogram (EEG) signals includes: an input terminal for receiving an EEG signal from a plurality of sensors coupled to a user; an analogue-to-digital converter arranged to receive the EEG signal from the input terminal and convert the EEG signal to a digital EEG signal; a data processing apparatus arranged to receive the digital EEG signal from the analogue-to-digital converter and programmed to process, in real time, the digital EEG signal using a first machine learning model to generate a cleaned EEG signal having a higher signal-to-noise ratio than the digital EEG signal; a power source arranged to provide electrical power to the analogue-to-digital converter and the data processing apparatus; and a housing containing the analogue-to-digital converter, the data processing apparatus, the power source, and a housing containing the analogue-to-digital converter,
- the data processing apparatus may be further programmed to process, in real time, the cleaned EEG signal to determine a selection by the user of one of a plurality of options presented to the user.
- the data processing apparatus may be programmed to perform mathematical transformations on the cleaned EEG signal using a second machine learning model to determine a selection by the user of one of a plurality of options presented to the user.
- the data processing apparatus includes a computer processor programmed to implement both the first and second machine learning models.
- the second machine learning model may be a neural network or other artificial intelligence architecture.
- the data processing apparatus may be programmed to synchronize the analysis with a presentation of the options to the user.
- the bioamplifier includes an output terminal for connecting the bioamplifier to a user interface and the data processing apparatus is programmed to synchronize the analysis with the presentation of the options to the user via the user interface.
- the user interface may be a component of an electronic device and the plurality of sensors and data processing apparatus are part of a closed-loop feedback system through which the user controls the electronic device.
- the electronic device may be selected from the group consisting of a networked device, a personal computer, a tablet computer, a mobile phone, and a wearable computer.
- the user interface may include an electronic display.
- the user interface may include a camera.
- the machine learning model may be a neural network or other artificial intelligence architecture.
- the bioamplifier may include an amplifier contained in the housing and arranged to receive the digital EEG signal from the analogue-to-digital converter and provide an amplified digital EEG signal to the data processing apparatus for processing.
- the power source may be a battery.
- the analogue-to-digital converter may be a 24 bit analogue-to-digital converter.
- the bioamplifier may have an input impedance of 10 MOhms or more.
- the input terminal may include a jack for receiving a connector from a lead.
- the input terminal may include a wireless transceiver for wirelessly receiving the EEG signal.
- An example method may include: receiving at least one EEG signal from a user via a plurality of sensors coupled to the user; amplifying, using a bioamplifier, the EEG signal from the plurality of sensors to provide an amplified EEG signal; processing, in real time, the amplified signal using a machine learning model that receives the amplified signal as input; and outputting a cleaned signal by the machine learning model, the cleaned signal having a higher signal-to-noise ratio than the at least one EEG signal received from the user.
- the method may further include processing, in real time, the cleaned EEG signal to determine a selection by the user of one of a plurality of options presented to the user.
- the method may further include sending a signal to an electronic device based on the selection determined from the cleaned EEG signal.
- An example electroencephalogram (EEG) sensor includes: a housing defining a chamber capable of storing a gel, the housing including a first chamber wall and a second chamber wall on the opposite side of the chamber from the first chamber wall, the first and second chamber walls each including a corresponding access port located on a common axis extending through the housing; an electrically-conductive probe with a probe tip extending at least partially through the chamber along the axis, at least a portion of the probe tip being exposed to the chamber; an electrical terminal located at an outer surface of the second chamber wall, the electrical terminal being in electrical communication with the probe tip through the access port at the second chamber wall; and a compliant member mechanically coupled to the access port at the first chamber wall capable of compressing, thereby providing a dispense pathway from the chamber through the access port at the first chamber wall.
- the access port at the first chamber wall may include an aperture through the first chamber wall.
- the compliant member may be a spring element attached to the electrically-conductive probe.
- the spring may be a spiral spring arranged co-axially with the axis.
- the spring may be mechanically attached to the electrically-conductive probe.
- the spring and electrically-conductive probe may be arranged so that axial pressure is applied to the tip causing the tip to retract into the chamber and compressing the spring.
- the compliant member may be a semi-permeable element.
- the semi-permeable element may be a sponge. Compression of the sponge may increase a permeability of the gel through the sponge.
- an electrically-conducting material disposed on an outer surface of the first chamber wall.
- the electrical terminal may include a connector for connecting to an electrical lead.
- the first chamber wall may include one or more additional access ports each defining a corresponding dispense pathway.
- An example apparatus includes the EEG sensor that includes a housing defining a chamber capable of storing a gel, the housing including a first chamber wall and a second chamber wall on the opposite side of the chamber from the first chamber wall, the first and second chamber walls each including a corresponding access port located on a common axis extending through the housing; an electrically-conductive probe with a probe tip extending at least partially through the chamber along the axis, at least a portion of the probe tip being exposed to the chamber; an electrical terminal located at an outer surface of the second chamber wall, the electrical terminal being in electrical communication with the probe tip through the access port at the second chamber wall; and a compliant member mechanically coupled to the access port at the first chamber wall capable of compressing, thereby providing a dispense pathway from the chamber through the access port at the first chamber wall.
- the apparatus also includes a pump in fluid communication with the chamber, the pump being arranged to apply pressure to a gel stored in the chamber.
- the pump may be configured to supply gel to the chamber. In other embodiments, the pump may be configured to supply pressured gas to the chamber.
- the pump may be a manual pump.
- the pump may be an electro-mechanical pump.
- the EEG sensor houses the pump.
- the pump may be in fluid communication with the chamber via a fluid channel.
- An example apparatus includes the EEG sensor disclosed above, further comprising an actuator and a signal generator in communication with the actuator, wherein during operation the actuator cause the EEG sensor to dispense gel through the dispense pathway in response to a signal from the signal generator.
- An example electroencephalogram system includes an EEG controller; and an EEG sensor including a contact surface, the contact surface comprising an electrically-conductive portion in communication with the EEG controller; and a sensor release element in communication with the EEG controller, the sensor release element being configured to perform, in response to a signal from the EEG controller, a release action to reduce adhesion of an electrically-conductive gel between the contact surface of the sensor and the user's skin.
- the sensor release element may include a heating element.
- the heating element may be arranged to heat the electrically-conductive gel to a temperature that reduces adhesion of an adhesive in the electrically-conductive gel.
- the heating element may be arranged to heat the electrically-conductive gel to a temperature that increase evaporation of the electrically-conductive gel relative to 98° F.
- the sensor release element may include a light emitting element.
- the light emitting element may emit radiation having energy at a wavelength that reduces adhesion of adhesive in the electrically-conductive gel.
- the light emitting element may emit ultra-violet radiation.
- the sensor release element may include an actuator.
- the actuator may change a shape of a surface of the EEG sensor to reduce adhesive forces between the sensor and the user's skin.
- the sensor release element includes a fluid dispense element.
- the fluid dispense element may dispense fluid including a solvent, a diluent, a surfactant, or a reagent to the gel.
- the fluid may reduce adhesion of an adhesive in the electrically-conductive gel.
- the EEG sensor may include a hygroscopic material in contact with the gel.
- the sensor release element may cause the hygroscopic material to release or absorb water to reduce adhesive forces between the sensor and the user's skin.
- An example method includes: applying an electrically-conducting gel to skin on a user's scalp; adhering a sensor to the subject's scalp with the electrically-conducting gel, the sensor including a sensor release element; acquiring electroencephalogram (EEG) signals using the sensor; and after acquiring the EEG, causing the sensor release element to perform a release action to reduce adhesion of the electrically-conductive gel between the senor and the user's skin.
- EEG electroencephalogram
- the release action may include heating the gel. In some embodiments, the release action includes delivering a release agent to the gel.
- the release agent may be a solvent, a reagent, or a surfactant.
- the release action may include changing a shape of a surface of the sensor.
- an example EEG sensor includes an auto-dispensing mechanism to automatically and/or continuously dispense conductive gel to a user's skin in order to achieve sufficient electrical contact to collect brain activity data.
- Exemplary EEG sensors can dispense a small volume of conductive gel in controlled amounts so that the EEG sensor can maintain electrical contact with a user's skin for a prolonged period of time.
- exemplary sensors' auto-dispense mechanisms apply conductive gel only to the area of the user's scalp where electrical contact is desired, avoiding waste and mess associated with manual application.
- highly adhesive gel can be used, maintaining contact and position on the user's skin during prolonged use.
- adhesive-containing gel can be used.
- sensors can include a sensor release element to reduce the adhesion of the conductive gel and facilitate clean, comfortable release of the sensor from the user's skin. This sensor release element within the EEG sensor quickly and easily delaminates the sensor from the user without requiring manual intervention.
- FIG. 1 is a schematic diagram of an embodiment of an EEG system.
- FIG. 2 is a flowchart showing aspects of the operation of the EEG system shown in FIG. 1
- FIG. 3 is a plot comparing two EEG signals for analysis using the system in FIG. 1 .
- FIG. 4 is a flowchart showing other aspects of the operation of the EEG system shown in FIG. 1 .
- FIG. 5 is a schematic diagram of an embodiment of an EEG system that features a head-mounted camera.
- FIG. 6 is a schematic diagram of another embodiment of an EEG system that features a mobile phone and a wireless connection to the system's sensor electrodes.
- FIG. 7A is a perspective view of an embodiment of a sensor electrode including multiple wire loops.
- FIG. 7B is a side view of the sensor electrode shown in FIG. 7A .
- FIG. 7C is a top view of the sensor electrode shown in FIG. 7A .
- FIG. 7D is a bottom view of the sensor electrode shown in FIG. 7A .
- FIG. 8 is a perspective view of another embodiment of a sensor electrode including multiple wire loops.
- FIG. 9 is a perspective view of an embodiment of a sensor electrode that includes wires of differing lengths.
- FIG. 10A is a perspective view of an embodiment of a sensor electrode that includes multiple protuberances.
- FIG. 10B is a side view of the sensor electrode shown in FIG. 10A .
- FIG. 10C is a top view of the sensor electrode shown in FIG. 10A .
- FIG. 10D is a bottom view of the sensor electrode shown in FIG. 10A .
- FIG. 11A is a perspective view of an embodiment of a sensor electrode that includes a protective collar.
- FIG. 11B is an exploded perspective view of the sensor electrode shown in FIG. 11A .
- FIG. 11C is a side view of the sensor electrode shown in FIG. 11A .
- FIG. 11D is a bottom view of the sensor electrode shown in FIG. 11A .
- FIG. 11E is a top view of the sensor electrode shown in FIG. 11A .
- FIG. 12 is an EEG system with an enlarged view of a sensor.
- FIGS. 13A and 13B are cross-sectional schematic diagrams of an embodiment of an EEG sensor that automatically dispenses electrically conductive gel.
- FIG. 14 is a cross-sectional schematic diagram of another embodiment of an EEG sensor that automatically dispenses electrically conductive gel.
- FIG. 15 is a cross-sectional schematic diagram of yet another embodiment of an EEG sensor that automatically dispenses electrically conductive gel.
- FIG. 16 is a cross-sectional schematic diagram of an embodiment of an EEG sensor that includes multiple probes connected to a single chamber that automatically dispense electrically conductive gel.
- FIG. 17A is a cross-sectional schematic diagram of an embodiment of an EEG sensor that contains an automatic release mechanism.
- FIG. 17B is a cross-sectional schematic diagram of an embodiment of an EEG sensor that contains an automatic release mechanism.
- FIG. 17C is a cross-sectional schematic diagram of an embodiment of an EEG sensor that contains an automatic release mechanism.
- FIG. 17D is a cross-sectional schematic diagram of an embodiment of an EEG sensor that contains an automatic release mechanism.
- FIG. 17E is a cross-sectional schematic diagram of an embodiment of an EEG sensor that contains an automatic release mechanism.
- FIG. 17F is a cross-sectional schematic diagram of an embodiment of an EEG sensor that contains an automatic release mechanism.
- FIG. 18 is a schematic diagram of a data processing apparatus that can be incorporated into an EEG system.
- an EEG system 100 features a portable bioamplifier 110 that collects and analyzes EEG signals from a user 101 using electrode sensors 136 , 137 , and 138 attached to user 101 's scalp.
- Bioamplifier 110 is in communication with a personal computer 140 which displays information 142 —in this instance an image of an ice cream cone—to user 101 .
- Bioamplifier 110 synchronously collects EEG signals from user 101 while displaying information 142 and analyzes the EEG signals, interpreting in real time user 101 's brain activity responsive to viewing the information.
- bioamplifier 110 is a high-impedance, low-gain amplifier with a high dynamic range.
- the bioamplifier impedance may be, for example, higher than 10 megaohms (e.g., 12 M ⁇ or more, 15 M ⁇ or more, 20 M ⁇ or more) with a maximum gain of 24 ⁇ amplification.
- the dynamic range of bioamplifier 110 should be sufficient to acquire the entire voltage range of typical EEG signals (e.g., 0.1 to 200 ⁇ V over frequency ranges of 1 to 100 Hz).
- bioamplifier 110 is housed within a compact, robust casing, providing a package that can be readily carried by user 101 , sufficiently robust to remain functional in non-laboratory settings.
- Electrode sensors 136 , 137 , and 138 may be dry sensors or may be placed in contact with the user's scalp using a gel. The sensors can be secured in place using, for example, adhesive tape, a headband, or some other headwear.
- One of sensors 136 , 137 , and 138 is an active sensor. Generally, the active sensor's location on the user's scalp depends on the location of brain activity of interest. In some implementations, the active sensor is placed at the back of the user's head, at or close to the user's inion. Another one of the sensors is a reference sensor. The EEG signal typically corresponds to measured electrical potential differences between the active sensor and the reference sensor. The third sensor is a ground sensor.
- the ground sensor is used for common mode rejection and can reduce (e.g., prevent) noise due to certain external sources, such as power line noise.
- the ground and/or reference sensors are located behind the user's ears, on the user's mastoid process.
- Bioamplifier 110 includes jacks 132 and 134 for connecting leads 135 and 143 to the electrode sensors and personal computer 140 , respectively.
- Bioamplifier 110 further includes an analogue-to-digital converter 112 , an amplifier 114 , and a processing module 120 .
- analogue-to-digital converter 112 and amplifier 114 may each have multiple channels, capable of converting and amplifying each EEG signal separately.
- a power source 130 e.g., a battery, a solar panel, a receiver for wireless power transmission
- analogue-to-digital converter 112 and amplifier 114 are selected to yield digital signals of sufficient amplitude to be processed using processing module 120 .
- Processing module 120 includes one or more computer processors programmed to analyze and clean amplified EEG signals received from amplifier 114 in real time.
- the computer processors can include commercially-available processors (e.g., a raspberry pi micro-controller) and/or custom components.
- processing module 120 includes one or more processors custom designed for neural network computations (e.g., Tensor Processing Unit from Google or Intel Nervanna NNP from Intel Corp.). Generally, processing module 120 should include sufficient computing power to enable real time cleaning and analysis of the EEG signals.
- processing module 120 are selected and programmed to include two machine learning (ML) models: a ML cleaning model 122 and a ML two-choice decision model 124 .
- ML cleaning model 122 receives raw EEG signals from amplifier 114 and, by application of a machine learning algorithm, cleans the signals to reduce noise.
- ML cleaning model 122 outputs cleaned EEG signals that have a reduced signal-to-noise ratio as compared with the input signals.
- Cleaning the EEG signal includes various operations that improve the usability of the signal for subsequent analysis, e.g., by reducing noise in the EEG signal.
- cleaning the EEG signal can include filtering the signal by applying a transfer function to input data, e.g., to attenuate some frequencies in the data and leave others behind.
- Other signal cleaning operations are also possible.
- signals can be cleaned using a neural network.
- Cleaning can also include operations to improve signal quality besides removal of undesirable frequencies. For instance, cleaning can include removing blinks, which digital filtering alone does not do.
- An EEG signal e.g., a time-varying voltage differential between a voltage measured using an active sensor and a reference sensor
- a bioamplifier e.g., bioamplifier 110
- the frequency at which the sensor voltage is sampled should be sufficient to capture voltage variations indicative of the brain activity of interest (e.g., between 0.1 and 10 Hz, at 10 Hz or more, at 50 Hz or more, at 100 Hz or more).
- An ADC (e.g., ADC 112 ) converts the signal from an analogue signal to a digital signal (step 220 ) and sends the digital signal to an amplifier (e.g., amplifier 114 ).
- the digital EEG signal is then amplified (e.g., by amplifier 114 ) (step 230 ), and the amplified signal sent to a processor (e.g., processing module 120 ).
- the processor e.g., processing module 120
- cleans the amplified signal using a machine learning model e.g., ML model 122
- a machine learning model e.g., ML model 122
- a filtered signal e.g., cleaned
- outputs the cleaned signal having increased signal-to-noise compared to an uncleaned EEG signal step 250 .
- the ML model is a neural network, which is an ML model that employs one or more layers of nonlinear units to predict an output for a received input.
- Some neural networks are deep neural networks that include two or more hidden layers in addition to the input and output layers. The output of each hidden layer is used as input to another layer in the network, i.e., another hidden layer, the output layer, or both.
- Some layers of the neural network generate an output from a received input, while some layers do not (remain “hidden”).
- the network may be recurrent or feedforward. It may have a single output or an ensemble of outputs; it may be an ensemble of architectures with a single output or a single architecture with a single output.
- a neural network for a machine learning model can be trained on EEG-specific data in order to distinguish between actual, usable data and noise.
- the ML model can be trained to classify artifacts in the EEG and to deal with EEG segments that have different types of noise in different ways. For example, if the network recognizes a vertical eye movement (a blink) it could attempt to remove the blink using a different approach than it would use if it recognized a horizontal eye movement.
- the ML model can be trained to clean data to an arbitrary level of precision—that is, it can clean up the raw data a little bit or a lot but there is no theoretical limit as to how closely the ML model can reproduce the type of clean data it was trained on. The level of cleaning that the ML model does is dependent only on time and the architecture of the model, that is, there is no theoretical maximum amount of possible cleaning.
- EEG signals even under controlled conditions, may contain significant noise, e.g., due to biological and/or electrical sources.
- the propensity for noise is further increased outside of a well-controlled laboratory environment.
- ML-based noise reduction may be particularly beneficial in providing usable EEG data in real time in real world (i.e., outside of a well-controlled environment) conditions.
- a processor e.g., processing module 120
- includes a machine learning two-choice decision model e.g., ML two-choice decision model 124 for analyzing cleaned EEG signals that output from a machine learning cleaning model (e.g., ML cleaning model 122 ).
- the two-choice model interprets a response of a user (e.g., user 101 ) to information (e.g., information 142 ) presented via a computer (e.g., computer 140 ).
- a user's response may be a selection of one choice among a finite set, e.g., two or more, of choices presented to the user.
- the two-choice model associates one of two binaries with information (e.g., information 142 ), such as interest (e.g., acceptance of an option) of the user in the information, or disinterest (e.g., rejection of an option).
- various parameters of the cleaned EEG signal can be used to determine the user's response (e.g., the user's choice selection). Often, these parameters include the amplitude of the response amplitude over a relevant time period (e.g., within about 500 ms of being presented with information 142 ). This is illustrated in the plot shown in FIG. 3 , for example, which compares two EEG signals corresponding to interest (trace 310 ) and disinterest (trace 320 ) in information presented to the user. After an initial latency of approximately 50 ms, trace 310 has a significantly larger amplitude than trace 320 .
- a machine learning model e.g., ML model 124 ) associates the higher amplitude with the user's interest, and returns this information to a computer (e.g., computer 140 ).
- a system e.g., system 100
- presents information e.g., information 142
- a user e.g., user 101
- a user interface for example, provided by a personal computer (e.g., personal computer 140 ).
- the system receives EEG signals from the system's sensors placed on (e.g., removably attached or otherwise coupled to) the user's scalp (step 420 ).
- the system e.g., system 100
- a machine learning model e.g., ML model 122
- the system (e.g., system 100 ) then provides the cleaned EEG signals as input to a machine learning model (e.g., ML model 124 ), which generates an output from the input indicating the user's response to information (e.g., information 142 ) or selection of an option (step 430 ).
- the system provides input and generates output in real-time to feed a closed loop.
- signal analysis involves correlating the cleaned EEG signal to the presentation of information to the user (e.g., by matching a time-stamp associated with signal to the time of presentation) and observing the time-varying amplitude of the signal associated with the user's brain activity responsive to the information.
- the system can decompose the signal into a time series of signal amplitude and/or change in signal amplitude and perform mathematical operations on the time series to determine the user's intent.
- the mathematical operations can associate a change in signal amplitude above a certain threshold and within a certain time (e.g., with 50 ms or less) of presenting the user with the information with a particular intention (e.g., an affirmative response) and a change in signal amplitude below the threshold with the opposite intention (e.g., a negative response).
- the threshold amplitude and/or response time can be determined by training the ML model.
- the system (e.g., system 100 ) then outputs results indicative of the user's response to the information (step 440 ).
- the user's response to the information may be a selection among multiple choices. For example, the user may be presented with a menu of options to order for dinner. The user may respond with EEG signals that the system can process to determine the user's dinner choice. The system can then output the selected dinner choice of the user.
- a bioamplifier e.g., bioamplifier 110
- can relay the results of two-choice decision model analysis to another device e.g., personal computer 140
- another device e.g., personal computer 140
- the cleaning and analysis processing occurs on the same processing module (e.g., using the same processor, e.g., the same processor core), the system does not need to send the signals across a network and therefore does not incur added data processing latency of network connections or bandwidth restrictions.
- the system executes calculations as soon as the amplified signal is ready for processing, providing a very low lag response to the user.
- the system can operate as a closed-loop system.
- the bioamplifier and other device e.g., personal computer 140
- the device can present the user with a choice between two or more different options and, based on the user's selection as interpreted from the associated EEG signals, present subsequent choices to the user associated with the user's prior choice.
- the system can use the received EEG signals from the user's brain activity to determine a user's selection among the finite set of possibilities and subsequently perform an action based on the user's selection without requiring the user to provide more input than the brain activity signals.
- a machine learning model e.g., ML model 124
- the cleaned data is presented to the machine learning model (e.g., ML model 124 ) and then the machine learning model (e.g., ML model 124 ) performs a number of mathematical transformations of the cleaned data in order to produce an output that reflects the intention of the user as encoded in the EEG data.
- the ML model is able to do this because it has been extensively trained, prior to interaction with the user, on what types of EEG signals correspond to what types of responses (e.g., selections by the user).
- the neural network can be a convolutional neural network model, a support vector machine, or a generative adversarial model.
- lower dimensional models e.g., a low featural multilayer perceptron or divergent autoencoder can be implemented.
- the minimum number of features that can be used to achieve acceptable accuracy in decoding the user's intention is preferred for computational simplicity.
- the optimized models may be trained or simulated in constrained computing environments in order to optimize for speed, power, or interpretability.
- Three primary features of optimization are 1) the number of features extracted (as described above), 2) the “depth” (number of hidden layers) of the model, and 3) whether the model implements recurrence. These features are balanced in order to achieve the highest possible accuracy while still allowing the system to operate in near real time on the embedded hardware.
- the machine learning model uses sub-selection in which the model only compares the current user's brain activity with other user samples that are most similar to that of the user in order to determine the user's selection. Similarity to other users can be operationalized with standard techniques such as waveform convolution and normalized cross correlation.
- the machine learning model e.g., ML model 124
- the dataset may contain brain activity samples from one or more other users. Samples for comparison are drawn either from 1) a data system's internal user data or 2) data collected from external users who have opted-in to having their data be included in the comparison database. All samples are anonymized and are non-identifiable.
- a system can present a user with a choice problem, e.g., a two-choice problem, using a display on a personal computer (e.g., computer 140 ) or some other interaction element.
- the system e.g., system 100
- the system provides the user with one object at a time, e.g., for 500 milliseconds, with random jitter, e.g., between 16 and 64 milliseconds, added between objects.
- Each image shown to the user is either an image of a first type of object or an image of a second type of object.
- the user Prior to displaying any images, the user is told to pay particular attention to the first type of object, e.g., by counting or some other means. While the system (e.g., system 100 ) is presenting images to the user, it differentiates EEG signals between when the user is paying particular attention to images of the first type of object and when the user is not paying as close of attention to images of the second type of object.
- the system e.g., system 100
- system 100 is presenting images to the user, it differentiates EEG signals between when the user is paying particular attention to images of the first type of object and when the user is not paying as close of attention to images of the second type of object.
- the system presents the user with sequence of images showing one of two different objects (e.g., a rabbit or a squirrel).
- the system Prior to displaying images, the user is told to pay particular attention to images of squirrels only, and to count the squirrels.
- the system e.g., system 100
- the machine learning model (e.g., ML model 124 ) can be trained using equal numbers of objects so that the model does not learn the true population frequency distribution of the objects in the user's world, which may impair the model's ability to distinguish between the user's choices.
- the system may be trained with equal numbers of squirrels and rabbits, though most users encounter squirrels more often than rabbits.
- the system After collecting samples from the user, the system (e.g., system 100 ) classifies the user's EEG signals to distinguish between EEG signals elicited when the user is focused on an image (e.g., views the squirrel in the example above) and when the user is not (e.g., the rabbit). This is accomplished by the machine learning model (e.g., ML model 124 ).
- the signals Prior to being passed to the ML system, the signals may be pre-processed, such as by boxcar filtering, range-normalization, or length normalization. The pre-processed signals are then passed to the machine learning model (e.g., ML system 124 ) for classification.
- the classification may be implemented in either a single-model fashion (i.e., classification is done by a single model) or in an ensemble-model fashion (i.e., a number of different types of models all make a classification and then the overall choice is made by a vote).
- the user samples can be added to the dataset in a database accessible to the system (e.g., system 100 ) and used to train subsequent neural network models.
- the system can use the ML model on any person for any decision task without further training.
- ML models can be trained on various characteristics of the user. For example, in some implementations, models may be trained on a specific age group, e.g., over 40 or under 20. The model may take into account a user's age and choose user samples in the same age range or choose from a subset of user samples in the database. As described above, the database will consist of both internal data and data from external users who have opted-in to their data being included in the comparison database. All samples are anonymized and non-identifiable. Individuals will have the option to include not only their EEG data, but other demographic data such as age and gender. System 100 can then use the trained model in real-life scenarios to distinguish between a selection event by the user and rejection.
- a specific age group e.g., over 40 or under 20.
- the model may take into account a user's age and choose user samples in the same age range or choose from a subset of user samples in the database.
- the database will consist of both internal data and data from external users who have opted-in to
- an EEG system e.g., EEG system 100
- EEG system 100 can present a user (e.g., user 101 ) with choices among a finite set, e.g., two or more, of possibilities, determine the choice that the user (e.g., user 101 ) has made based on EEG signals from brain activity, and then perform further actions based on the user's choice.
- the user e.g., user 101
- the system e.g., system 100
- the system e.g., system 100
- the user can choose a contact from a list of multiple contacts and place a phone call the chosen contact using only the user's brain activity.
- the EEG system e.g., EEG system 100
- sequentially presents the user e.g., user 101
- a computer e.g., computer 140
- the system e.g., system 100
- presents the user e.g., user 101
- options for contacting the selected contact e.g., call, text, share, or email.
- the system identifies the user's selection based on received EEG signals corresponding to the user's brain activity representing a selection of an option.
- the system e.g., system 100
- an EEG system 500 includes bioamplifier 110 interfaced with a head-mounted camera system 510 which is arranged to track user 101 's field of view.
- Camera system 510 includes a camera 512 and onboard image processing for analyzing images captured by the camera of user 101 's field of view.
- EEG system 500 is configured to facilitate user 101 's interaction with an object 522 associated with a quick response (QR) code 520 (as illustrated) or bar codes, NFC tags, or some other identification feature readily identifiable using machine vision.
- QR quick response
- An EEG system analyzes EEG signals from a user (e.g., user 101 ) associated with brain waves responsive to a viewing object (e.g., viewing object 522 ) synchronously with reading a QR code (e.g., QR code 520 ).
- the analysis returns one of two binary choices, which the system associates with the viewing object (e.g., object 522 ) based on the system viewing the QR code (e.g., QR code 520 ).
- an EEG system 600 includes a mobile phone 610 and a head-mounted sensor system 620 .
- Mobile phone 610 includes a wireless transceiver 612 , a display 622 , and a camera 614 .
- Sensor system 610 includes a transceiver unit 620 and sensors 636 , 637 , and 638 connected to the transceiver unit.
- the sensors measure EEG signals as described above, but the signals are related to receiver 612 using a wireless signal transmission protocol, e.g., Bluetooth®, near-field communication (NFC), or some other short-distance protocol.
- a wireless signal transmission protocol e.g., Bluetooth®, near-field communication (NFC), or some other short-distance protocol.
- a mobile phone e.g., mobile phone 610
- displays information e.g., information 624
- a user e.g., user 101
- a display e.g., display 622
- receives and analyzes EEG signals from a transceiver unit e.g., transceiver unit 620
- the mobile phone e.g., mobile phone 610
- a user e.g., user 101
- can use a camera e.g., camera 614 to capture information in their environment (e.g., to scan a QR code) while the phone receives and analyzes their associated brain waves.
- the EEG systems described above can use a variety of different sensors to obtain the EEG signals.
- the sensor electrodes are “dry” sensor which feature one or more electrodes that directly contact the user's scalp without a conductive gel. Dry sensors can be desirable because they are simpler to attach and their removal does not involve the need to clean up excess gel.
- a sensor generally includes one or more electrodes for contacting the user's scalp.
- a sensor 700 includes multiple wire loop electrodes 720 mounted on a base 710 , and a press stud electrode 730 on the opposite side of base 710 from wire loop electrodes 720 .
- Wire loop electrodes 720 are bare electrically-conducting wires that are in electrical contact with metal press stud 730 .
- a lead featuring female press stud fastener, is connected to press stud 730 , connecting sensor 700 to a bioamplifier or transceiver.
- the multiple loop electrodes provide redundant contact points with the user's scalp, increasing the likelihood that the sensor maintains good electrical contact with the user's scalp.
- sensor electrode 700 includes a total of eight wire loop electrodes arranged symmetrically about an axis. More generally, the number of wire loop electrodes can vary as desired. The length of the wire loop electrodes (from base to tip) can also vary as desired. For instance, a user with long hair may select a sensor with longer wire loops than a user with shorter hair.
- FIG. 8 shows another sensor electrode 800 similar to sensor electrode 700 but with shorter wire loop electrodes 820 . In general, the loop electrodes can have a length from about 1 mm to about 15 mm.
- FIG. 9 shows yet a further sensor electrode 900 that includes multiple wire electrodes 920 .
- Wire electrodes 920 can be sufficiently flexible so that the user can bend them to provide optimal contact with the scalp.
- Each wire electrode 920 can have the same length, or the lengths of the wires can vary.
- a sensor electrode 1000 features multiple protuberances 1040 supported by a base 1010 .
- the protuberances are formed from a relatively soft material, such as a rubber.
- protuberances 1040 are arranged in two concentric rings.
- the protuberances in the inner ring each include a wire electrode 1020 which protrudes from the tip of the respective protuberance.
- the protruding wire electrodes can be relatively short, reducing possible user discomfort due to the excessive pressure on the user's scalp.
- a further example of a sensor electrode 1100 includes a base 1110 , wire electrodes 1120 , a press stud electrode 1130 , and a protective cap 1140 (e.g., a plastic cap).
- the cap can reduce the likelihood that the user's hair becomes ensnared in the electrode, e.g., where the electrodes are attached to the base.
- wet sensors are used.
- Wet sensors are those in which an electrically-conducting gel, e.g., commercially-available gels such as ECI Electro-Gel from Electro-Cap International, Inc. or Spectra 360 from Parker Laboratories, facilitates electrical contact between the electrode and the user's scalp.
- gel can be dispensed onto the user's scalp manually, e.g., by the user or a technician, or using an automated dispense mechanism.
- gel can include an adhesive to promote adhesion of the sensor to the user's scalp. Adhesive gels can facilitate use of EEG systems in non-laboratory settings.
- a wet sensor can include an element that facilitates release of the electrode from the user's scalp.
- a sensor release element provides a stimulus (e.g., a thermal stimulus, chemical stimulus, radiation stimulus) to reduce adhesion of the sensor to the user's scalp, e.g., by changing the adhesion properties of the gel and/or the properties of the sensor itself.
- a stimulus e.g., a thermal stimulus, chemical stimulus, radiation stimulus
- Such sensor release elements can facilitate use of more aggressive adhesives in the gel than, for example, adhesives that would simply involve mechanical removal from the scalp, like a Band-Aid.
- an EEG system 1200 features a wet sensor 1220 that is coupled to a user 1201 's scalp with a conductive gel 1230 .
- EEG system 1200 includes an EEG controller 1210 (including, e.g., a bioamplifier as described above) and sensor 1220 connected by a lead 1215 .
- sensor 1220 includes a sensor electrode 1222 , a gel dispense element 1224 , and sensor release element 1226 .
- Sensor 1220 also includes an electrical connector 1228 to which lead 1215 is connected. Electrical connections (e.g., wires) connect sensor electrode 1222 , gel dispense element 1224 , and sensor release element 1226 to connector 1228 .
- Sensor electrode 1222 is an electrically-conductive element that is positioned sufficiently close to the user's skin to detect electrical activity in the user's brain.
- sensor electrode 1222 is composed of an electrically-conductive material, such as a conducting metal (e.g., copper, aluminum), a metal alloy, or non-metal electrically-conducting material (e.g., a conducting polymer).
- a conducting metal e.g., copper, aluminum
- metal alloy e.g., copper, aluminum
- non-metal electrically-conducting material e.g., a conducting polymer.
- sensor electrode 1222 includes a pin that extends from the outer wall of the sensor towards the user.
- sensor electrode 1222 can include a layer of a conducting material coating the surface of the sensor facing the user.
- gel dispense element 1224 dispenses electrically-conductive gel 1230 which contains an adhesive.
- the adhesive in gel 1230 bonds the surface of sensor 1220 to user 1201 's skin, maintaining electrical conduction between sensor 1220 and user 1201 .
- the gel dispense element 1224 can automatically gel 1230 in small amounts based on signals from EEG controller 1210 , optimizing electrical contact of the sensor to user 1201 and providing a comfortable experience to the user. Gel can be dispensed continuously or periodically while the sensor is in use.
- gel dispense element 1224 can use a variety of different mechanisms to dispense gel to the user's scalp.
- gel dispense element 1224 relies on a contract-driven release mechanism to dispense gel.
- pressure of contact with a user's head causes gel to dispense from the sensor to a user's head.
- Gel dispense element 1224 can be purely mechanical in its applications of conductive gel using force to retract and extend a probe into a housing storing conductive gel, thereby creating a dispense pathway from the chamber through the access port at the first chamber wall.
- gel dispense element 1224 includes a mechanism 1232 , e.g.
- a pump or an actuator that can be in electrical communication with EEG controller 1210 by lead 1215 .
- An electrical pathway can be formed from EEG controller 1210 to lead 1215 and then to gel dispense element 1224 .
- EEG controller 1210 sends control signals to mechanism 1232 causing gel dispense element 1224 to dispense gel to the skin, e.g., scalp, of user 1201 .
- Exemplary gel dispense elements are described below.
- the adhesive used in the gel should be miscible in the gel and not react adversely with the user's skin, while providing a desirable level of adhesive between the sensor and the user's skin.
- acrylate-based adhesives such as methacrylates and epoxy diacrylates (also known as vinyl resins) may be employed. Cyanoacrylate adhesives can also be used.
- siloxane adhesives can be used.
- the adhesives may be, for example, a blend of Polyvinyl Alcohol with salt (e.g., NaCL or KCl).
- Sensor release element 1226 facilitates easy and comfortable release of the sensor from a user's head by changing the properties of the adhesive in the gel or the properties of the sensor, or both.
- the release mechanism employed by sensor release element 1226 depends on the nature of the adhesive used in the gel. Control signals from EEG controller 1210 activate sensor release element 1226 to facilitate delamination of sensor 1220 from user 1201 as described in detail below. Examples of specific release mechanisms are described below.
- an example sensor 1300 with a gel dispense mechanism includes a single point probe 1312 extending through a reservoir 1302 containing conductive gel 1311 .
- Sensor 1300 further includes a shaft 1315 that houses a spiral spring 1305 (or other compliant member) that connects probe 1312 to a lead connector 1328 .
- Probe 1312 , spring 1305 , and connector 1328 provide an electrically-conductive pathway that extends from a wall 1326 of reservoir 1302 that faces the user through the reservoir's opposite wall 1324 .
- Wall 1326 includes an aperture 1310 providing an access port to the gel reservoir. This aperture provides a dispense pathway.
- Probe 1312 includes a tip 1322 sized to seal aperture 1310 .
- probe 132 when spring 1305 is in an uncompressed state, probe 132 extends sufficiently far into reservoir 1302 so that tip 1322 seals aperture 1310 , preventing flow of gel out of the reservoir.
- probe 1312 retracts into the reservoir, compressing spring 1305 and opening aperture 1310 , thereby allowing flow of the gel out of the sensor as illustrated in FIG. 13B .
- a mechanism provides compression of the probe tip to actively constrain the gel cavity (e.g., put pressure on a bladder or a paddle) to compel the gel out of the opening.
- the gel may be pressurized as described in FIG. 14 .
- gel can be dispensed simply by applying pressure on the sensor sufficient to push the probe back into the reservoir. Once the pressure is removed, force from spring 1305 pushes probe tip 1322 back to seal aperture 1310 , stopping gel flow to the user's skin.
- EEG sensor 1300 dispenses gel in response to signals from the EEG controller.
- the EEG controller can monitor the quality of EEG signals measured using sensor 1300 and cause gel to dispense once the signal quality reduces past a pre-set threshold.
- EEG sensor 1300 can monitor an electrical impedance at the user's scalp and cause gel to dispense when impedance exceeds a pre-set threshold. Above the pre-set threshold value, the EEG sensor can dispense either a standard volume of additional gel or continually dispense gel until the impedance is again below the threshold value.
- the EEG sensor needs an additional restriction to the dispense logic in order to identify whether the sensor is sufficiently close to a user's scalp. Dispensing gel will not improve signal quality or impedance if the sensor is not close to the user.
- the additional determination regarding proximity to a user's scalp may require an additional sensor, such as a temperature sensor to indicate proximity to skin, an accelerometer to indicate that motion of the sensor no longer matches to motion of other sensors, or an optical sensor to indicate that the sensor sees light and is therefore not flush against the scalp.
- software logic can determine if dispensing a small amount of gel changes the impedance or signal quality. If not, the logic can give up and send an error signal.
- the senor can include an electro-mechanical actuator (e.g., a piezo-electric actuator) in place of or in addition to spring 1305 which causes retraction and extension of the probe to open and seal aperture 1310 .
- an electro-mechanical actuator e.g., a piezo-electric actuator
- the components of sensor 1300 are formed from materials and by methods suitable for their purposes.
- probe 1312 is formed from a rigid, electrically-conductive material, such as a metal or metal-coated plastic.
- Chamber 1302 may be made out of plastic, e.g., printed using a 3D printer.
- the size and shape of the sensor are selected so that the reservoir is sufficiently large to hold gel commensurate with the length of time the system is in use, while being sufficiently small so that the sensor is reasonably unobtrusive and comfortable for extended use.
- the reservoir can hold sufficient gel for an hour or more of continuous use (e.g., 8-10 hours).
- the reservoir has a volume in a range from about 1 ml to about 10 ml.
- each gel dispense causes the sensor to dispense sufficient gel to provide adequate electrical-conductivity between the sensor and the user's skin. This can depend on, e.g., the nature of the gel, the size of the probe tip, among other factors. Generally, the probe dispenses sufficiently small volumes of gel so as not to wet a larger area of the user's scalp than is necessary. In certain embodiments, the sensor can dispense a fraction of a milliliter to a few milliliters in each event (e.g., 0.05 ml or more, 0.1 ml or more, 0.5 ml or more, 1 ml or more, such as 10 ml or less, 5 ml or less, 2 ml or less).
- a feedback system is used to continuously or periodically dispense gel during an extended period of sensor use to maintain good electrically connectivity of the sensor during the use period.
- the reservoir can be pressurized to facilitate dispensing the gel through the aperture.
- an EEG sensor 1400 includes a volume of pressurized gas 1420 the portion of reservoir 1302 not filled by gel 1311 . The gas pressure in the reservoir forces gel 1311 out of aperture 1310 when probe 1312 retracts tip 1322 into the reservoir.
- Sensor 1400 includes a gas source (e.g., a pump and/or pressurized gas cylinder) 1401 that in connected to reservoir 1302 via a tube 1410 .
- a gas source e.g., a pump and/or pressurized gas cylinder
- Manual pumps e.g., a syringe
- electromechanical pumps can be used, for example.
- the tube connects to reservoir 1302 at a port 1429 in wall 1324 .
- the connection to gas source 1401 ensures that the gas pressure in reservoir 1302 is maintained at sufficient pressure as the volume of gel in the chamber reduces.
- the base of chamber 1502 includes a sponge (or some other gel-permeable material) 1550 that facilitates transport of gel 1511 from chamber 1502 to user 1510 's skin.
- the end of probe 1522 contacts the internal surface of sponge 1550 and may compress sponge 1550 against user 1510 's skin.
- Sponge 1550 absorbs electrically conductive gel from chamber 1502 and coats user 1510 's skin with the gel when the user 1510 presses against the sponge.
- Probe 1522 has a first wall that compresses against the sponge and a second wall that, although not shown, is electrically-connected to a lead. The lead is connected to an EEG controller, creating an electrical pathway from the probe to the EEG controller.
- an example implementation may have multiple probes 1645 a - c connected to a single chamber 1602 as illustrated. Each probe separately engages a user 1610 's skin. However, the probes 1645 a - c share a common reservoir from which they draw conductive gel, and in some implementations pressurized gas or liquid. Chamber 1602 may contain gel 1611 only or may contain both gel 1611 and a pressurized element as described above with respect to FIG. 14 .
- the multiple probes may be purely mechanical, e.g., spring-loaded, or they may be automatically controlled by an EEG controller.
- the probes may be connected to a gel-permeable material that facilitates transfer of the conductive gel to a user's skin as described above with respect to FIG. 15 .
- multiple probes are placed in a headband or other headgear so that the probes are easy to affix to a user's head.
- a chamber for an EEG sensor that holds conductive gel may be refillable at the tip of the probe, e.g., using a syringe.
- conductive gel may be pumped through a separate inlet into the chamber.
- inlet 1429 is described as being used only for pressurized gas or liquid, this inlet may also be used to pump in conductive gel.
- the gel includes an adhesive, which can be thermally released.
- the gel can contain an adhesive which has adhesive properties that degrade at elevated temperatures and/or the gel can evaporate with application of heat.
- a sensor 1720 a includes a sensor release element that features a heating element 1771 , e.g., a heating coil, which heats gel between sensor 1720 and the user's skin upon activation.
- heating element 1771 causes release of a gel 1230 in a variety of ways.
- heating element 1771 facilitates evaporation of a component of gel 1230 to cause release.
- the heating can degrade or otherwise chemically alter the adhesive in gel 1230 so that adhesion of the sensor to the user's skin is reduced.
- Heating element 1771 may be located close to an access point, or aperture, of sensor 1720 a to emit heat from the sensor through the aperture to evaporate a portion or all of conductive gel 1230 .
- the EEG controller can send signals to heating element 1771 to control operation of heating element 1771 to time heat application with the desired release. Release can be prompted by the user, e.g., by entering a command via an input interface in communication with the EEG controller.
- Heating element 1771 can alternatively maintain a gel component in an adhesive phase at an elevated temperature and, upon cessation of heating, cause release. Again, heating element 1771 may be located close to an access point, or aperture, of sensor 1720 a to emit heat from the sensor through the access point to heat conductive gel 1230 and facilitate release. The EEG controller determines when and by how much to decrease or increase the temperature of the heating element 1771 in order to release the sensor from a user's head.
- thermal release should be performed at temperatures that are comfortable for the user.
- the transition from adhesive to non-adhesive gel should occur at a temperature that is greater than body temperature but less than a temperature at which the user's skin will burn or otherwise experience pain. In some embodiments, this temperature can be in a range from 100° F. to about 120° F.
- heating element 1771 operates in concert with a hygroscopic material 1772 to cause the material to absorb and/or release water to control the adhesive properties of gel 1230 .
- Hygroscopic material 1772 may heat up from heating element 1771 and may absorb conductive gel 1230 through an access point of sensor 1720 b .
- hygroscopic material 1772 can release a liquid, e.g., water, through the aperture of the sensor to detach the sensor from the user's head.
- EEG controller 1210 sends a signal through an electrical pathway from the controller to lead 1215 and to sensor release element 1226 containing heating element 1771 . This signal initiates detachment of the sensor from the user by causing a change in temperature of the heating element. This change of temperature causes the hygroscopic material to heat or cool in a manner that delaminates the sensor from the user's skin.
- FIG. 17C shows a sensor 1720 c including a heating element 1771 on a user's 1201 head. Heating element 1771 causes user 1201 to sweat 1777 , which then causes gel 1230 to release as illustrated.
- a sensor release element contains a solvent dispenser 1782 as illustrated in FIG. 17D .
- a solvent dispenser 1782 may be a dispenser, e.g., a micro-fluidic pump, that dispenses a solvent into gel 1230 to facilitate release from user 1201 's skin by dissolving (or otherwise physically and/or chemically reacting with) the adhesive in the gel.
- Solvent dispenser 1782 delivers the solvent through a channel 1785 that connects solvent dispenser 1782 with the outer surface of sensor 1720 d.
- the solvent is selected based on the chemistry of the adhesive in the gel and its compatibility with a person's skin.
- water is sufficient.
- the solvent is an organic solvent, such as alcohol.
- Surfactants can also be used to change the surface chemistry of the gel. For example, anionic, amphoteric, or cationic surfactants can be used to alter the interaction of the gel with the user's skin, facilitating release.
- surfactants include sodium lauryl sulfate, ammonium laureth sulfate, disodium lauryl sulfosuccinate, Cocoamphocarboxyglycinate, decyl Polyglucoside, cetearyl alcohol, stearyl alcohol, Cocamidopropyl Betaine, Decyl Glucoside, Glyceryl Cocoate, Sodium Cocoyl Isethionate, Almond Glycerides, Sodium Lauryl Sulphoacetate, Sodium Lauroyl Sarcosinate, sodium methyl cocoyl taurate, Sucrose Cocoate, and polysorbate.
- sensor release element 1226 of FIG. 12 may contain a light source 1791 , e.g., an ultraviolet (UV) LED with a wavelength selected to cause bond formation or bond breaking in the adhesive in gel 1230 .
- a light source 1791 e.g., an ultraviolet (UV) LED with a wavelength selected to cause bond formation or bond breaking in the adhesive in gel 1230 .
- UV-curing adhesives or UV-degrading adhesives can be used.
- an infrared light source can be used to heat the gel.
- a sensor release element 1792 includes an actuator 1795 (e.g., a piezo electric actuator) that changes a shape of the contact surface to cause delamination of a sensor 1720 f from user 1701 's skin.
- actuator 1795 e.g., a piezo electric actuator
- activation by a signal from the EEG controller can cause actuator 1795 to reduce its dimension in the direction shown by the arrows in FIG. 17F .
- This compression causes the edges of sensor 1720 f to pull away from user's skin 1201 , thereby facilitating delamination from the sensor.
- sensor 1220 may include only one of a gel dispense element 1224 or a sensor release element 1226 .
- adhesive gel can be applied manually, e.g., by a technician or by the user directly.
- sensor release element 1226 is not included in sensor 1220 , sensor 1220 can be removed from user 1201 's skin manually.
- the EEG systems described above can be used to accomplish a variety of computer-based tasks.
- the disclosed system and techniques can be used to perform tasks commonly performed using a networked computer device (e.g., a mobile phone), such as ordering food, scheduling a flight, interacting with household or personal electronic devices, and/or purchasing a ticket for an event.
- the system can be used for user interaction with objects that have QR codes, bar codes, NFC tags, or another type of identification feature on them so that a system can detect the object with which the user is interacting and determine tasks associated with the object.
- objects can be objects in a user's home such as a thermostat, television, phone, oven, or other electronic device.
- an automated pet door in the user's house may have an associated QR code.
- the system may determine that the user is interacting with the door with their mobile phone. The system then can present the user with a list of options associated with the pet door on their phone. The system can then collect and analyze the user's EEG signals to determine what action the user would like the system to perform, in this example, whether or not to lock the pet door. Similarly, a system (e.g., EEG system 100 ) may use a user's phone or other computing device to notice proximity of a smart device. Proximity can be recognized by wireless or wired connectivity, (e.g., Bluetooth®, near field communication, RFID, or GPS). Once proximity is determined, the system can present the user with a choice related the smart device.
- wireless or wired connectivity e.g., Bluetooth®, near field communication, RFID, or GPS
- a user's phone may be able to notice that it is in proximity to a smart thermostat, such as a Nest®, a Honeywell® Lyric Round, or a Netatmo's thermostat, and then present the user with a choice about whether the user would like the temperature to be warmer or colder.
- a smart thermostat such as a Nest®, a Honeywell® Lyric Round, or a Netatmo's thermostat
- the system could then adjust the temperature in the room on the basis of the user's EEG, without the user having to physically interact with the thermostat.
- a smart device e.g., a smart home device such as an Amazon Alexa®, Google Home®, or Wemo WEMO® plug device
- a smart home device such as an Amazon Alexa®, Google Home®, or Wemo WEMO® plug device
- turning a smart light on or off turning the volume of a smart speaker up or down, or making a decision to buy or not to buy what is in a digital shopping cart.
- Embodiments of the subject matter and the functional operations described in this specification can be implemented in digital electronic circuitry, in tangibly-embodied computer software or firmware, in computer hardware, including the structures disclosed in this specification and their structural equivalents, or in combinations of one or more of them.
- Embodiments of the subject matter described in this specification can be implemented as one or more computer programs, i.e., one or more modules of computer program instructions encoded on a tangible non-transitory storage medium for execution by, or to control the operation of, data processing apparatus.
- the computer storage medium can be a machine-readable storage device, a machine-readable storage substrate, a random or serial access memory device, or a combination of one or more of them.
- the program instructions can be encoded on an artificially-generated propagated signal, e.g., a machine-generated electrical, optical, or electromagnetic signal, that is generated to encode information for transmission to suitable receiver apparatus for execution by a data processing apparatus.
- an artificially-generated propagated signal e.g., a machine-generated electrical, optical, or electromagnetic signal
- data processing apparatus refers to data processing hardware and encompasses all kinds of apparatus, devices, and machines for processing data, including by way of example a programmable processor, a computer, or multiple processors or computers.
- the apparatus can also be, or further include, special purpose logic circuitry, e.g., an FPGA (field programmable gate array) or an ASIC (application-specific integrated circuit).
- the apparatus can optionally include, in addition to hardware, code that creates an execution environment for computer programs, e.g., code that constitutes processor firmware, a protocol stack, a database management system, an operating system, or a combination of one or more of them.
- a computer program which may also be referred to or described as a program, software, a software application, an app, a module, a software module, a script, or code, can be written in any form of programming language, including compiled or interpreted languages, or declarative or procedural languages; and it can be deployed in any form, including as a stand-alone program or as a module, component, subroutine, or other unit suitable for use in a computing environment.
- a program may, but need not, correspond to a file in a file system.
- a program can be stored in a portion of a file that holds other programs or data, e.g., one or more scripts stored in a markup language document, in a single file dedicated to the program in question, or in multiple coordinated files, e.g., files that store one or more modules, sub-programs, or portions of code.
- a computer program can be deployed to be executed on one computer or on multiple computers that are located at one site or distributed across multiple sites and interconnected by a data communication network.
- the processes and logic flows described in this specification can be performed by one or more programmable computers executing one or more computer programs to perform functions by operating on input data and generating output.
- the processes and logic flows can also be performed by special purpose logic circuitry, e.g., an FPGA or an ASIC, or by a combination of special purpose logic circuitry and one or more programmed computers.
- Computers suitable for the execution of a computer program can be based on general or special purpose microprocessors or both, or any other kind of central processing unit.
- a central processing unit will receive instructions and data from a read-only memory or a random access memory or both.
- the essential elements of a computer are a central processing unit for performing or executing instructions and one or more memory devices for storing instructions and data.
- the central processing unit and the memory can be supplemented by, or incorporated in, special purpose logic circuitry.
- a computer will also include, or be operatively coupled to receive data from or transfer data to, or both, one or more mass storage devices for storing data, e.g., magnetic, magneto-optical disks, or optical disks.
- a computer need not have such devices.
- a computer can be embedded in another device, e.g., a mobile telephone, a personal digital assistant (PDA), a mobile audio or video player, a game console, a Global Positioning System (GPS) receiver, or a portable storage device, e.g., a universal serial bus (USB) flash drive, to name just a few.
- PDA personal digital assistant
- GPS Global Positioning System
- USB universal serial bus
- Computer-readable media suitable for storing computer program instructions and data include all forms of non-volatile memory, media and memory devices, including by way of example semiconductor memory devices, e.g., EPROM, EEPROM, and flash memory devices; magnetic disks, e.g., internal hard disks or removable disks; magneto-optical disks; and CD-ROM and DVD-ROM disks.
- semiconductor memory devices e.g., EPROM, EEPROM, and flash memory devices
- magnetic disks e.g., internal hard disks or removable disks
- magneto-optical disks e.g., CD-ROM and DVD-ROM disks.
- embodiments of the subject matter described in this specification can be implemented on a computer having a display device, e.g., a CRT (cathode ray tube) or LCD (liquid crystal display) monitor, for displaying information to the user and a keyboard and a pointing device, e.g., a mouse or a trackball, by which the user can provide input to the computer.
- a display device e.g., a CRT (cathode ray tube) or LCD (liquid crystal display) monitor
- keyboard and a pointing device e.g., a mouse or a trackball
- Other kinds of devices can be used to provide for interaction with a user as well; for example, feedback provided to the user can be any form of sensory feedback, e.g., visual feedback, auditory feedback, or tactile feedback; and input from the user can be received in any form, including acoustic, speech, or tactile input.
- a computer can interact with a user by sending documents to and receiving documents from a device that is used by the user; for example, by sending web pages to a web browser on a user's device in response to requests received from the web browser.
- a computer can interact with a user by sending text messages or other forms of message to a personal device, e.g., a smartphone, running a messaging application, and receiving responsive messages from the user in return.
- Embodiments of the subject matter described in this specification can be implemented in a computing system that includes a back-end component, e.g., as a data server, or that includes a middleware component, e.g., an application server, or that includes a front-end component, e.g., a client computer having a graphical user interface, a web browser, or an app through which a user can interact with an implementation of the subject matter described in this specification, or any combination of one or more such back-end, middleware, or front-end components.
- the components of the system can be interconnected by any form or medium of digital data communication, e.g., a communication network. Examples of communication networks include a local area network (LAN) and a wide area network (WAN), e.g., the Internet.
- LAN local area network
- WAN wide area network
- the computing system can include clients and servers.
- a client and server are generally remote from each other and typically interact through a communication network. The relationship of client and server arises by virtue of computer programs running on the respective computers and having a client-server relationship to each other.
- a server transmits data, e.g., an HTML page, to a user device, e.g., for purposes of displaying data to and receiving user input from a user interacting with the device, which acts as a client.
- Data generated at the user device e.g., a result of the user interaction, can be received at the server from the device.
- FIG. 18 shows a schematic diagram of a generic computer system 1800 .
- the system 1800 can be used for the operations described in association with any of the computer-implemented methods described previously, according to one implementation.
- the system 1800 includes a processor 1810 , a memory 1820 , a storage device 1830 , and an input/output device 1840 .
- Each of the components 1810 , 1820 , 1830 , and 1840 are interconnected using a system bus 1850 .
- the processor 1810 is capable of processing instructions for execution within the system 1800 .
- the processor 1810 is a single-threaded processor.
- the processor 1810 is a multi-threaded processor.
- the processor 1810 is capable of processing instructions stored in the memory 1820 or on the storage device 1830 to display graphical information for a user interface on the input/output device 1840 .
- the memory 1820 stores information within the system 1800 .
- the memory 1820 is a computer-readable medium.
- the memory 1820 is a volatile memory unit.
- the memory 1820 is a non-volatile memory unit.
- the storage device 1830 is capable of providing mass storage for the system 1800 .
- the storage device 1830 is a computer-readable medium.
- the storage device 1830 may be a floppy disk device, a hard disk device, an optical disk device, or a tape device.
- the input/output device 1840 provides input/output operations for the system 1200 .
- the input/output device 1840 includes a keyboard and/or pointing device.
- the input/output device 1840 includes a display unit for displaying graphical user interfaces.
- real-time refers to transmitting or processing data without intentional delay given the processing limitations of a system, the time required to accurately obtain data and images, and the rate of change of the data and images.
- real-time is used to describe concurrently receiving, cleaning, and interpreting EEG signals. Although there may be some actual delays, such delays generally do not prohibit the signals from being cleaned and analyzed within sufficient time such that the data analysis remains relevant to provide decision-making feedback and accomplish computer-based tasks. For example, adjustments to a smart thermostat are calculated based on user EEG signals. Cleaned signals are analyzed to determine the user's desired temperature before enough time has passed to render the EEG signals irrelevant.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- User Interface Of Digital Computer (AREA)
Abstract
Description
Claims (20)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/855,904 US10722134B2 (en) | 2017-12-27 | 2017-12-27 | Gel-assisted electroencephalogram sensor electrode |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/855,904 US10722134B2 (en) | 2017-12-27 | 2017-12-27 | Gel-assisted electroencephalogram sensor electrode |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| US20190192030A1 US20190192030A1 (en) | 2019-06-27 |
| US10722134B2 true US10722134B2 (en) | 2020-07-28 |
Family
ID=66949149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US15/855,904 Expired - Fee Related US10722134B2 (en) | 2017-12-27 | 2017-12-27 | Gel-assisted electroencephalogram sensor electrode |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US10722134B2 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10898137B2 (en) | 2017-12-27 | 2021-01-26 | X Development Llc | Gel-assisted electroencephalogram sensor electrode |
| US11647953B2 (en) | 2018-02-08 | 2023-05-16 | X Development Llc | Hair ratcheting electroencephalogram sensors |
| EP4537755A1 (en) * | 2023-10-09 | 2025-04-16 | Time is Brain, SL | Biosignal registering system |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9820670B2 (en) | 2016-03-29 | 2017-11-21 | CeriBell, Inc. | Methods and apparatus for electrode placement and tracking |
| US10716487B2 (en) | 2017-12-27 | 2020-07-21 | X Development Llc | Sub-dermally implanted electroencephalogram sensor |
| US20230190175A1 (en) * | 2021-12-17 | 2023-06-22 | Microsoft Technology Licensing, Llc | Lightweight electroencephalogram monitoring device with semi-dry electrodes |
| WO2025224240A1 (en) * | 2024-04-25 | 2025-10-30 | Braincapture Aps | Applicator for gel application, related electronic device and gel application system |
| CN119924776B (en) * | 2024-12-30 | 2025-10-28 | 北京津发科技股份有限公司 | Multifunctional photoelectric signal acquisition sensor and multi-mode brain signal acquisition device |
Citations (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1230921A (en) | 1913-05-08 | 1917-06-26 | William J Paul | Safety-guard. |
| US4125110A (en) * | 1975-11-25 | 1978-11-14 | Hymes Alan C | Monitoring and stimulation electrode |
| USD327325S (en) | 1990-04-02 | 1992-06-23 | Minnesota Mining And Manufacturing Company | Electrode |
| USD369667S (en) | 1994-04-18 | 1996-05-07 | Medicotest A/S | Electrode |
| USD378614S (en) | 1994-10-17 | 1997-03-25 | Medicotest A/S | Electrode |
| USD385037S (en) | 1994-10-17 | 1997-10-14 | Medicotest A/S | Electrode |
| US5823832A (en) | 1996-12-23 | 1998-10-20 | Netech Corporation | Electrical connector for use with an electroencephalograph electrode |
| USD429337S (en) | 1999-10-21 | 2000-08-08 | Sanfilippo Robert M | Electrode |
| US6175753B1 (en) | 1999-07-02 | 2001-01-16 | Baltimore Biomedical, Inc. | Methods and mechanisms for quick-placement electroencephalogram (EEG) electrodes |
| US20010044573A1 (en) | 1999-02-05 | 2001-11-22 | Samir Manoli | EEG electrode and EEG electrode locator assembly |
| US20020052610A1 (en) | 2000-04-07 | 2002-05-02 | Skakoon James G. | Deep organ access device and method |
| US6574513B1 (en) | 2000-10-03 | 2003-06-03 | Brainmaster Technologies, Inc. | EEG electrode assemblies |
| USD478173S1 (en) | 2001-10-11 | 2003-08-05 | Medicotest A/S | Electrode |
| USD478668S1 (en) | 2003-01-27 | 2003-08-19 | Stephen Todd Epstein | Electrode |
| US20050192594A1 (en) | 2002-09-17 | 2005-09-01 | Skakoon James G. | Low profile instrument immobilizer |
| US6998031B1 (en) | 1999-07-01 | 2006-02-14 | Atraverda Limited | Electrode |
| USD536673S1 (en) | 2004-08-16 | 2007-02-13 | Koninklijke Philips Electronics N.V. | Electrode |
| US20070255127A1 (en) | 2006-03-20 | 2007-11-01 | Frederick Mintz | Mobile electroencephalograph data collection and diagnosis system |
| USD567374S1 (en) | 2006-03-16 | 2008-04-22 | Aaron Medical Industries, Inc. | Electrode |
| US20080269842A1 (en) | 2007-04-27 | 2008-10-30 | Giftakis Jonathon E | Implantable medical device for treating neurological conditions with an initially disabled cardiac therapy port and leadless ECG sensing |
| US20100100001A1 (en) | 2007-12-27 | 2010-04-22 | Teledyne Scientific & Imaging, Llc | Fixation-locked measurement of brain responses to stimuli |
| USD625823S1 (en) | 2007-08-30 | 2010-10-19 | Cheetah Medical Ltd. | Electrode |
| US20110046503A1 (en) | 2009-08-24 | 2011-02-24 | Neurofocus, Inc. | Dry electrodes for electroencephalography |
| US20110125046A1 (en) | 2001-06-13 | 2011-05-26 | David Burton | Methods and apparatus for monitoring consciousness |
| US8112141B2 (en) | 2007-05-22 | 2012-02-07 | Persyst Development Corporation | Method and device for quick press on EEG electrode |
| US20120035441A1 (en) * | 2010-08-05 | 2012-02-09 | Arkray, Inc. | Mount unit, sensor unit, measurement apparatus and sensor fixation method |
| US20130110212A1 (en) | 2011-10-28 | 2013-05-02 | Hon Hai Precision Industry Co., Ltd. | Electrode lead of pacemaker and pacemaker |
| US20140316230A1 (en) | 2013-04-22 | 2014-10-23 | Personal Neuro Devices Inc. | Methods and devices for brain activity monitoring supporting mental state development and training |
| US20140347265A1 (en) | 2013-03-15 | 2014-11-27 | Interaxon Inc. | Wearable computing apparatus and method |
| US9055927B2 (en) | 2011-11-25 | 2015-06-16 | Persyst Development Corporation | User interface for artifact removal in an EEG |
| US9186084B2 (en) | 2013-03-22 | 2015-11-17 | National Chiao Tung University | Line-contact dry electrode |
| US20150327789A1 (en) * | 2012-12-05 | 2015-11-19 | Smartbrain As | Electrode |
| US20150374255A1 (en) * | 2014-06-29 | 2015-12-31 | Curzio Vasapollo | Adhesive-Mountable Head-Wearable EEG Apparatus |
| USD758595S1 (en) | 2013-11-25 | 2016-06-07 | China Qingdao Bright Medical Manufacturing Co., Ltd. | Electrode |
| US20160228693A1 (en) | 2015-02-09 | 2016-08-11 | Arnold B. Vardiman | Bilateral deep brain stimulator |
| USD768096S1 (en) | 2014-11-12 | 2016-10-04 | Medicus Engineering Aps | Electrode |
| USD783818S1 (en) | 2015-05-11 | 2017-04-11 | Karl Storz Gmbh & Co. Kg | Electrode |
| USD791956S1 (en) | 2016-05-06 | 2017-07-11 | Konan Medical Usa, Inc. | Electrode |
| US20180085573A1 (en) | 2016-09-27 | 2018-03-29 | National Guard Health Affairs | Skull implanted electrode assembly for brain stimulation |
| WO2018068013A1 (en) | 2016-10-06 | 2018-04-12 | The Regents Of The University Of California | An implantable electrocorticogram brain-computer interface system for restoring extremity movement |
| US20190192031A1 (en) | 2017-12-27 | 2019-06-27 | X Development Llc | Sub-Dermally Implanted Electroencephalogram Sensor |
| US20190192078A1 (en) | 2017-12-27 | 2019-06-27 | X Development Llc | Gel-assisted electroencephalogram sensor electrode |
| US20190192075A1 (en) | 2013-01-03 | 2019-06-27 | Vladimir Kranz | Additive Equipment to Basic Equipment with Advantage in Form of Multimedial, Health, Sport or another Equipment Convenient for Adding by Additive Equipment |
| US20190239763A1 (en) | 2016-07-14 | 2019-08-08 | Sidewaystrategies Llc | System and methods for improving diagnostic evoked potential studies for functional assessments of nerves and nerve pathways |
| US20190239807A1 (en) | 2018-02-08 | 2019-08-08 | X Development Llc | Hair ratcheting electroencephalogram sensors |
-
2017
- 2017-12-27 US US15/855,904 patent/US10722134B2/en not_active Expired - Fee Related
Patent Citations (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1230921A (en) | 1913-05-08 | 1917-06-26 | William J Paul | Safety-guard. |
| US4125110A (en) * | 1975-11-25 | 1978-11-14 | Hymes Alan C | Monitoring and stimulation electrode |
| USD327325S (en) | 1990-04-02 | 1992-06-23 | Minnesota Mining And Manufacturing Company | Electrode |
| USD369667S (en) | 1994-04-18 | 1996-05-07 | Medicotest A/S | Electrode |
| USD378614S (en) | 1994-10-17 | 1997-03-25 | Medicotest A/S | Electrode |
| USD385037S (en) | 1994-10-17 | 1997-10-14 | Medicotest A/S | Electrode |
| US5823832A (en) | 1996-12-23 | 1998-10-20 | Netech Corporation | Electrical connector for use with an electroencephalograph electrode |
| US20010044573A1 (en) | 1999-02-05 | 2001-11-22 | Samir Manoli | EEG electrode and EEG electrode locator assembly |
| US6640122B2 (en) | 1999-02-05 | 2003-10-28 | Advanced Brain Monitoring, Inc. | EEG electrode and EEG electrode locator assembly |
| US6998031B1 (en) | 1999-07-01 | 2006-02-14 | Atraverda Limited | Electrode |
| US6175753B1 (en) | 1999-07-02 | 2001-01-16 | Baltimore Biomedical, Inc. | Methods and mechanisms for quick-placement electroencephalogram (EEG) electrodes |
| USD429337S (en) | 1999-10-21 | 2000-08-08 | Sanfilippo Robert M | Electrode |
| US20020052610A1 (en) | 2000-04-07 | 2002-05-02 | Skakoon James G. | Deep organ access device and method |
| US6574513B1 (en) | 2000-10-03 | 2003-06-03 | Brainmaster Technologies, Inc. | EEG electrode assemblies |
| US20110125046A1 (en) | 2001-06-13 | 2011-05-26 | David Burton | Methods and apparatus for monitoring consciousness |
| USD478173S1 (en) | 2001-10-11 | 2003-08-05 | Medicotest A/S | Electrode |
| US20050192594A1 (en) | 2002-09-17 | 2005-09-01 | Skakoon James G. | Low profile instrument immobilizer |
| USD478668S1 (en) | 2003-01-27 | 2003-08-19 | Stephen Todd Epstein | Electrode |
| USD536673S1 (en) | 2004-08-16 | 2007-02-13 | Koninklijke Philips Electronics N.V. | Electrode |
| USD567374S1 (en) | 2006-03-16 | 2008-04-22 | Aaron Medical Industries, Inc. | Electrode |
| US20070255127A1 (en) | 2006-03-20 | 2007-11-01 | Frederick Mintz | Mobile electroencephalograph data collection and diagnosis system |
| US20080269842A1 (en) | 2007-04-27 | 2008-10-30 | Giftakis Jonathon E | Implantable medical device for treating neurological conditions with an initially disabled cardiac therapy port and leadless ECG sensing |
| US8112141B2 (en) | 2007-05-22 | 2012-02-07 | Persyst Development Corporation | Method and device for quick press on EEG electrode |
| USD625823S1 (en) | 2007-08-30 | 2010-10-19 | Cheetah Medical Ltd. | Electrode |
| US20100100001A1 (en) | 2007-12-27 | 2010-04-22 | Teledyne Scientific & Imaging, Llc | Fixation-locked measurement of brain responses to stimuli |
| US20110046503A1 (en) | 2009-08-24 | 2011-02-24 | Neurofocus, Inc. | Dry electrodes for electroencephalography |
| US20120035441A1 (en) * | 2010-08-05 | 2012-02-09 | Arkray, Inc. | Mount unit, sensor unit, measurement apparatus and sensor fixation method |
| US20130110212A1 (en) | 2011-10-28 | 2013-05-02 | Hon Hai Precision Industry Co., Ltd. | Electrode lead of pacemaker and pacemaker |
| US9055927B2 (en) | 2011-11-25 | 2015-06-16 | Persyst Development Corporation | User interface for artifact removal in an EEG |
| US9232922B2 (en) | 2011-11-25 | 2016-01-12 | Persyst Development Corporation | User interface for artifact removal in an EEG |
| US20150327789A1 (en) * | 2012-12-05 | 2015-11-19 | Smartbrain As | Electrode |
| US20190192075A1 (en) | 2013-01-03 | 2019-06-27 | Vladimir Kranz | Additive Equipment to Basic Equipment with Advantage in Form of Multimedial, Health, Sport or another Equipment Convenient for Adding by Additive Equipment |
| US20140347265A1 (en) | 2013-03-15 | 2014-11-27 | Interaxon Inc. | Wearable computing apparatus and method |
| US9186084B2 (en) | 2013-03-22 | 2015-11-17 | National Chiao Tung University | Line-contact dry electrode |
| US9314184B2 (en) | 2013-03-22 | 2016-04-19 | National Chiao Tung University | Line-contact dry electrode |
| US9314185B2 (en) | 2013-03-22 | 2016-04-19 | National Chiao Tung University | Line-contact dry electrode |
| US20140316230A1 (en) | 2013-04-22 | 2014-10-23 | Personal Neuro Devices Inc. | Methods and devices for brain activity monitoring supporting mental state development and training |
| USD758595S1 (en) | 2013-11-25 | 2016-06-07 | China Qingdao Bright Medical Manufacturing Co., Ltd. | Electrode |
| US20150374255A1 (en) * | 2014-06-29 | 2015-12-31 | Curzio Vasapollo | Adhesive-Mountable Head-Wearable EEG Apparatus |
| USD768096S1 (en) | 2014-11-12 | 2016-10-04 | Medicus Engineering Aps | Electrode |
| US20160228693A1 (en) | 2015-02-09 | 2016-08-11 | Arnold B. Vardiman | Bilateral deep brain stimulator |
| USD783818S1 (en) | 2015-05-11 | 2017-04-11 | Karl Storz Gmbh & Co. Kg | Electrode |
| USD791956S1 (en) | 2016-05-06 | 2017-07-11 | Konan Medical Usa, Inc. | Electrode |
| US20190239763A1 (en) | 2016-07-14 | 2019-08-08 | Sidewaystrategies Llc | System and methods for improving diagnostic evoked potential studies for functional assessments of nerves and nerve pathways |
| US20180085573A1 (en) | 2016-09-27 | 2018-03-29 | National Guard Health Affairs | Skull implanted electrode assembly for brain stimulation |
| WO2018068013A1 (en) | 2016-10-06 | 2018-04-12 | The Regents Of The University Of California | An implantable electrocorticogram brain-computer interface system for restoring extremity movement |
| US20190192031A1 (en) | 2017-12-27 | 2019-06-27 | X Development Llc | Sub-Dermally Implanted Electroencephalogram Sensor |
| US20190192078A1 (en) | 2017-12-27 | 2019-06-27 | X Development Llc | Gel-assisted electroencephalogram sensor electrode |
| US20190239807A1 (en) | 2018-02-08 | 2019-08-08 | X Development Llc | Hair ratcheting electroencephalogram sensors |
Non-Patent Citations (8)
| Title |
|---|
| ASET Department of Education Report, McNall, Faye. (Apr. 17, 2014.) How do you clean a patient's head after removing EEG electrodes? [Online]. https://asetdeptedu.blogspot.com/2014/04/how-do-you-clean-patients-head-after.html. [Accessed Jan. 15, 2020], hereinafter referred to as ASET (Year: 2014). * |
| Berg et al. "The Cyberlink Interface: Development of a Hands-Free Continuous/Discrete Mutli-Channel Computer Input Device," United Stated Air Force Research Laboratory, AFRL-HE-WP-TR-1999-0191, Feb. 1999, 63 pages. |
| Hasan et al. "Prediction of Epileptic Seizure by Analysing Time Series EEG Signal Using k-NN Classifier," Applied Bionics and Biomechanics, Aug. 2017, 12 pages. |
| Krishnan et al. "ActiveClean: An Interactive Data Clearning Framework for Modern Machine Learning," SIGMOD, Jun. 2016, 4 pages. |
| Liao et al. "Gaming control using a wearable and wireless EEG-based brain-computer interface device with novel dry foam-based sensors," Journal of NeuroEngineering and Rehabilitation, 9(5), Jan. 28, 2012, 12 pages. |
| Ries et al. "Response-Locked Brain Dynamics of Word Production," PLoS One, 8(3), Mar. 12, 2013, 14 pages. |
| Telpaz et al. "Using EEG to predict consumers' future choices," Journal of Marketing Research, 52(4), Aug. 2015, 60 pages. |
| www.frontiernerds.com [online] "How to Hack Toy EEGs," Apr. 7, 2010, [retrieved on Apr. 16, 2020] Retrieved from Internet: URL<http://www.frontiernerds.com/brain-hack> 92 pages. |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10898137B2 (en) | 2017-12-27 | 2021-01-26 | X Development Llc | Gel-assisted electroencephalogram sensor electrode |
| US11647953B2 (en) | 2018-02-08 | 2023-05-16 | X Development Llc | Hair ratcheting electroencephalogram sensors |
| EP4537755A1 (en) * | 2023-10-09 | 2025-04-16 | Time is Brain, SL | Biosignal registering system |
| WO2025078436A1 (en) * | 2023-10-09 | 2025-04-17 | Time Is Brain, Sl | Biosignal registering system |
Also Published As
| Publication number | Publication date |
|---|---|
| US20190192030A1 (en) | 2019-06-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10722134B2 (en) | Gel-assisted electroencephalogram sensor electrode | |
| US10898137B2 (en) | Gel-assisted electroencephalogram sensor electrode | |
| US11009952B2 (en) | Interface for electroencephalogram for computer control | |
| US10716487B2 (en) | Sub-dermally implanted electroencephalogram sensor | |
| US10901508B2 (en) | Fused electroencephalogram and machine learning for precognitive brain-computer interface for computer control | |
| US20190192024A1 (en) | Electroencephalogram system with reconfigurable network of redundant electrodes | |
| US10952680B2 (en) | Electroencephalogram bioamplifier | |
| US11647953B2 (en) | Hair ratcheting electroencephalogram sensors | |
| AU2023241380B2 (en) | Localized collection of biological signals, cursor control in speech-assistance interface based on biological electrical signals and arousal detection based on biological electrical signals | |
| CN112016367A (en) | Emotion recognition system and method and electronic equipment | |
| CN111012323B (en) | Device for estimating blood pressure and device for supporting blood pressure estimation | |
| CN113764099A (en) | Psychological state analysis method, device, equipment and medium based on artificial intelligence | |
| CN107072532A (en) | Physiological signal detection and analysis system and equipment | |
| Kumar et al. | Neuro-phone: An assistive framework to operate Smartphone using EEG signals | |
| KR20200040563A (en) | Apparatus and method for estimating blood pressure | |
| JP2022502803A (en) | Systems and methods for integrating emotional data into social network platforms and sharing emotional data on social network platforms | |
| Alam et al. | GeSmart: A gestural activity recognition model for predicting behavioral health | |
| CN111542285A (en) | Methods and systems for characterizing users of personal care devices | |
| JP2013246517A (en) | Nonverbal information collection apparatus and nonverbal information collection program | |
| Newcombe et al. | Internet of things enabled technologies for behaviour analytics in elderly person care: A survey | |
| Radhakrishnan et al. | Wearables for in-situ monitoring of cognitive states: Challenges and opportunities | |
| KR20120066274A (en) | Terminal device for emotion recognition and terminal device for emotion display | |
| RU2779067C2 (en) | Methods and systems for determination of characteristics of user of personal hygiene device | |
| CN119183060B (en) | Stress prediction method for hearing aid system based on real-time monitoring of hormone levels | |
| Summoogum et al. | Comparing Traditional Machine Learning with Deep Learning based approaches for Applied Acoustic Gait Analysis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FEPP | Fee payment procedure |
Free format text: ENTITY STATUS SET TO UNDISCOUNTED (ORIGINAL EVENT CODE: BIG.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
|
| AS | Assignment |
Owner name: X DEVELOPMENT LLC, CALIFORNIA Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:WATSON, PHILIP EDWIN;SARGENT, JOSEPH HOLLIS;EISAMAN, MATTHEW DIXON;AND OTHERS;SIGNING DATES FROM 20180111 TO 20180118;REEL/FRAME:044688/0992 |
|
| STPP | Information on status: patent application and granting procedure in general |
Free format text: DOCKETED NEW CASE - READY FOR EXAMINATION |
|
| STPP | Information on status: patent application and granting procedure in general |
Free format text: RESPONSE TO NON-FINAL OFFICE ACTION ENTERED AND FORWARDED TO EXAMINER |
|
| STPP | Information on status: patent application and granting procedure in general |
Free format text: NON FINAL ACTION MAILED |
|
| STPP | Information on status: patent application and granting procedure in general |
Free format text: RESPONSE TO NON-FINAL OFFICE ACTION ENTERED AND FORWARDED TO EXAMINER |
|
| STPP | Information on status: patent application and granting procedure in general |
Free format text: NOTICE OF ALLOWANCE MAILED -- APPLICATION RECEIVED IN OFFICE OF PUBLICATIONS |
|
| STPP | Information on status: patent application and granting procedure in general |
Free format text: PUBLICATIONS -- ISSUE FEE PAYMENT VERIFIED |
|
| STCF | Information on status: patent grant |
Free format text: PATENTED CASE |
|
| FEPP | Fee payment procedure |
Free format text: MAINTENANCE FEE REMINDER MAILED (ORIGINAL EVENT CODE: REM.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
|
| LAPS | Lapse for failure to pay maintenance fees |
Free format text: PATENT EXPIRED FOR FAILURE TO PAY MAINTENANCE FEES (ORIGINAL EVENT CODE: EXP.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
|
| STCH | Information on status: patent discontinuation |
Free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362 |
|
| FP | Lapsed due to failure to pay maintenance fee |
Effective date: 20240728 |