US1048185A - Making clear and durable hemaglobin preparations. - Google Patents
Making clear and durable hemaglobin preparations. Download PDFInfo
- Publication number
- US1048185A US1048185A US42130408A US1908421304A US1048185A US 1048185 A US1048185 A US 1048185A US 42130408 A US42130408 A US 42130408A US 1908421304 A US1908421304 A US 1908421304A US 1048185 A US1048185 A US 1048185A
- Authority
- US
- United States
- Prior art keywords
- hemaglobin
- durable
- preparations
- making clear
- glycerin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Description
No Drawing.
UNITED Tl OFFICE 'rHILiPr LIWY. orimnLm-wrnmnnsnonr; ennmm;
MAKING 0mm in nimaBLE HEMAGLQIBIN i imraxwrrous;
pound of the red blood corpuscles after being liberated from the serum-and clarified,
In the manufacture of hema-globin prepa-, rations the following process, is generally resorted toqThe cloudy hemaglobin is first clarified by means of. ether, chloroform,
spirit, or the like, the clarifier being after-' ward separated from the hemaglobin preparat-ion by heating or by any other suitable method; -The clarified hemaglobin solution is thereupon preserved by adding to the same a suitable quantity of glycerin. It is evident that the blood corpuscles which are easily decomposed, are not favorably affected by these numerous reactions. The color of the hemaglobin, for instance, which is origi-, 'nally red, is turned-into browmsh-red by. the process, 2. e., aconversion to oxyhema-- globin and met-hemaglobin takes place. The present invention relates to a process of clarifying-andpreserving the hemaglobin which process, apart from being simplerthan the ordinary processes, retains the' original color of the hemaglobin.
The viscid and cloudy hemaglobin, sepa- Speiflcatioirof Letters Iatent. Application'filed March 1a, 1908. Serial No. 421,304.
' Patented Dec. 24,1912.
rated from theserum by centrifugal action,
is directlymixed with a quantity of chemically pure glycerinand then centrifuged .tovgetherywith the-latter so that an intimate contact of the different molecules takes place. The glycerin, of which, owing to thecen- ,trifugal action towhich the solution is sub- 'jected, only a small quantity is required, clarifies the hemaglobin at the same time as it serves as a preservative for'the same.
For instance 100 parts of hemaglobin-aremixed with 25 parts of glycerin. v The mixture havingv passedthe centrifuge is perfectly clear, but no separation of glycerin has. taken place. In this manner the hema globin is only subjected to one single reaction and. it retains its origlnal red color.
Therefore the present process is particularly suitablein'the preparation of such extracts which,- owing to the small quantity of glycerin needed, can .be made to contQin a larger percentage of hemaglobin, 4 I-claim:
A process for making clear, hemaglobincontaining preparation, consisting in separatingthe blood corpuscles from the serum bv centrifugal action, then mixing the clarified mass with arelatively small quantity of glycerin, centrifuging this mixture, substan tiallyas and for the purpose set forth.
In testimony whereof I haveherelmto set my hand in the presence of two witnesses.
PHILIPP LEWX.
"Witnesses:
HENR Hasrrm, Wonnnmaa
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42130408A US1048185A (en) | 1908-03-16 | 1908-03-16 | Making clear and durable hemaglobin preparations. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42130408A US1048185A (en) | 1908-03-16 | 1908-03-16 | Making clear and durable hemaglobin preparations. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US1048185A true US1048185A (en) | 1912-12-24 |
Family
ID=3116453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US42130408A Expired - Lifetime US1048185A (en) | 1908-03-16 | 1908-03-16 | Making clear and durable hemaglobin preparations. |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US1048185A (en) |
-
1908
- 1908-03-16 US US42130408A patent/US1048185A/en not_active Expired - Lifetime
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