US1046056A - Capsule. - Google Patents
Capsule. Download PDFInfo
- Publication number
- US1046056A US1046056A US71712512A US1912717125A US1046056A US 1046056 A US1046056 A US 1046056A US 71712512 A US71712512 A US 71712512A US 1912717125 A US1912717125 A US 1912717125A US 1046056 A US1046056 A US 1046056A
- Authority
- US
- United States
- Prior art keywords
- capsule
- liquid
- medicine
- syrup
- capsules
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002775 capsule Substances 0.000 title description 15
- 239000007788 liquid Substances 0.000 description 14
- 239000003814 drug Substances 0.000 description 13
- 235000020357 syrup Nutrition 0.000 description 6
- 239000006188 syrup Substances 0.000 description 6
- 240000007472 Leucaena leucocephala Species 0.000 description 5
- 235000010643 Leucaena leucocephala Nutrition 0.000 description 5
- 206010011224 Cough Diseases 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000007937 lozenge Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 244000215068 Acacia senegal Species 0.000 description 2
- 229920000084 Gum arabic Polymers 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 235000010489 acacia gum Nutrition 0.000 description 2
- 239000000205 acacia gum Substances 0.000 description 2
- ISAOCJYIOMOJEB-UHFFFAOYSA-N benzoin Chemical compound C=1C=CC=CC=1C(O)C(=O)C1=CC=CC=C1 ISAOCJYIOMOJEB-UHFFFAOYSA-N 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 240000008574 Capsicum frutescens Species 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 241001379910 Ephemera danica Species 0.000 description 1
- 244000166124 Eucalyptus globulus Species 0.000 description 1
- 240000001238 Gaultheria procumbens Species 0.000 description 1
- 235000007297 Gaultheria procumbens Nutrition 0.000 description 1
- 241000219506 Phytolacca Species 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 244000028419 Styrax benzoin Species 0.000 description 1
- 235000000126 Styrax benzoin Nutrition 0.000 description 1
- 235000008411 Sumatra benzointree Nutrition 0.000 description 1
- 241000779819 Syncarpia glomulifera Species 0.000 description 1
- 229960002130 benzoin Drugs 0.000 description 1
- 239000001390 capsicum minimum Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000010411 cooking Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 235000019382 gum benzoic Nutrition 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 239000012907 medicinal substance Substances 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 1
- 239000001739 pinus spp. Substances 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000020354 squash Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 229940036248 turpentine Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S264/00—Plastic and nonmetallic article shaping or treating: processes
- Y10S264/37—Processes and molds for making capsules
Definitions
- the object of the present invention is to provide an improved capsule for administering liquid medicines.
- the invention is particularly well adapted for administering medicines for throat and bronchial affections, which must be applied direct to the parts to be treated.
- the ordinary gelatin capsule which is intended to be dissolved in the stomach,
- Liquid medicine administered by a capsule is much preferable to the ordinary cough drop, lozenge,
- a capsule cancontain a far greater quantity of the medicine in proportion to its size than a cough drop or lozenge.
- the latter are formed by a proc ess which involves cooking at a high tem perature, during which the strength of the medicine is greatly reduced.
- capsule I mix a liquid medicine prepared according to any desired formula with sugar, and powdered acacia or gum arabic, in the proportions of 50.1bs: of syrup, 50 oz. of the liquid medicine and 4 oz. of acacia.
- a medicine which I have used is one composed of the following. ingredients:-collinsonia 4 oz.; phytolacca 4 oz.; benzoin 8 oz.; menthol 1 oz.; capsicum 2 oz.; wintergreen 5 oz.; eucalyptus 24 oz.; turpentine 11 ⁇ oz.
- the sugar is first cooked to a syrup, and then the medicine and acacia are added.
- the acacia serves to keep the oils of the liquid medicine thoroughly mixed in the syrup; otherwise the oils would rise to the top of the syrup and not be equally distributed throughout.
- the mixture is then poured troche, or the like, for the reason that not only can the contents ofithe cap--. sule be administered directly to the, affected Patented Dec. 3, 1912.
- candies known as cordials, or'liquor drops having the form of capsules containing liquid contents have been made by using a shell'of crystallized sugar, but said candies do not have the coatingoflacacia and are not hermetically sealed and the contents will evaporate in a comparatively short time.
- my invention. difi'ers therefrom in that not only the liquidcontents, but the shell itself, contain the medicine to be administered.
- the great value of this invention resides in the fact that medicines can thus be carried about in a liquid form for an indefinite period, and administered immediately to the parts to be treated, merely bycrushing them in the mouth, and, further, that said capsules contain, inthe same volume, a much greater quantity of medicinal substance than cough drops, lozenges, troches, or the like.
- I claim 2+ In combination with a'liquid substance having medicinal properties, a capsule hermetically inclosing the same and composed of said substance and others in a solid form.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Description
UNITED STATES PATENT onmcn.
FRED H. DRAKE, F OAKLAND,CALIFOBNIA.
CAPSULE.
1,046,056, Specification of Letters Patent.
No Drawing.
To all whom it my concern:
Be it known that I, FRED I-I. DRAKE, a citizen of the United States, residing at Oakland, in the county of Alameda and State of California, have invented new and useful Improvements in Capsules, of which the following is a specification.
The object of the present invention is to provide an improved capsule for administering liquid medicines.
The invention is particularly well adapted for administering medicines for throat and bronchial affections, which must be applied direct to the parts to be treated. Obviouslythe ordinary gelatin capsule, which is intended to be dissolved in the stomach,
is unsuitable for this purpose. Liquid medicine administered by a capsule is much preferable to the ordinary cough drop, lozenge,
;or the like, but a capsule cancontain a far greater quantity of the medicine in proportion to its size than a cough drop or lozenge.
Moreover, the latter are formed by a proc ess which involves cooking at a high tem perature, during which the strength of the medicine is greatly reduced. With my im-' proved capsule, as 'will hereinafter appear,
the medicinal strength of the liquid is completely retained.
Inpreparing my improved, capsule I mix a liquid medicine prepared according to any desired formula with sugar, and powdered acacia or gum arabic, in the proportions of 50.1bs: of syrup, 50 oz. of the liquid medicine and 4 oz. of acacia. Such a medicine which I have used is one composed of the following. ingredients:-collinsonia 4 oz.; phytolacca 4 oz.; benzoin 8 oz.; menthol 1 oz.; capsicum 2 oz.; wintergreen 5 oz.; eucalyptus 24 oz.; turpentine 11} oz. The sugar is first cooked to a syrup, and then the medicine and acacia are added. The acacia serves to keep the oils of the liquid medicine thoroughly mixed in the syrup; otherwise the oils would rise to the top of the syrup and not be equally distributed throughout. The mixture is then poured troche, or the like, for the reason that not only can the contents ofithe cap--. sule be administered directly to the, affected Patented Dec. 3, 1912.
Application filed August 26, 1912. Serial No. 717,125.
into starch molds, whereupon that part of the liquid coming in contact with the starch, immediately hardens, forming a shell, which envelops the liquid which has not so come in contact, and therefore remains in a liquid condition. After drying 24 hours, syrup at a proper temperature is poured over the capsules, which syrup then crystallizes. The capsules are then dried again, andare placed in a revolving kettle, where they are panned in a mixture of sugar, liquid medicine and acacia or gum arabic. The last step above described of the process of forming the capsule is extremely important, as thereby the capsule is given a tough coating which 'is impervious to air and liquid, so that my improved capsules can remain for an indefinite period unaltered. I am aware that candies known as cordials, or'liquor drops, having the form of capsules containing liquid contents have been made by using a shell'of crystallized sugar, but said candies do not have the coatingoflacacia and are not hermetically sealed and the contents will evaporate in a comparatively short time. Moreover, my invention. difi'ers therefrom in that not only the liquidcontents, but the shell itself, contain the medicine to be administered.
As' already intimated, the great value of this invention resides in the fact that medicines can thus be carried about in a liquid form for an indefinite period, and administered immediately to the parts to be treated, merely bycrushing them in the mouth, and, further, that said capsules contain, inthe same volume, a much greater quantity of medicinal substance than cough drops, lozenges, troches, or the like.
I claim 2+ In combination with a'liquid substance having medicinal properties, a capsule hermetically inclosing the same and composed of said substance and others in a solid form.
In testimony whereof I have hereunto set my hand in the presence of two subscribing witnesses.
FRED H. DRAKE. Witnesses:
FRANCIS M. WRIGHT, D. B. RICHARDS.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71712512A US1046056A (en) | 1912-08-26 | 1912-08-26 | Capsule. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71712512A US1046056A (en) | 1912-08-26 | 1912-08-26 | Capsule. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US1046056A true US1046056A (en) | 1912-12-03 |
Family
ID=3114329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US71712512A Expired - Lifetime US1046056A (en) | 1912-08-26 | 1912-08-26 | Capsule. |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US1046056A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2566645A (en) * | 1941-12-12 | 1951-09-04 | Den Bergh S En Jurgens Fabriek | Method and means for making seamless capsules |
| US2766478A (en) * | 1951-10-15 | 1956-10-16 | Gasoline Res Ind And Commercia | Encapsulating method and apparatus |
| US4762719A (en) * | 1986-08-07 | 1988-08-09 | Mark Forester | Powder filled cough product |
| USH1228H (en) | 1990-10-04 | 1993-09-07 | Medicated lollipop |
-
1912
- 1912-08-26 US US71712512A patent/US1046056A/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2566645A (en) * | 1941-12-12 | 1951-09-04 | Den Bergh S En Jurgens Fabriek | Method and means for making seamless capsules |
| US2766478A (en) * | 1951-10-15 | 1956-10-16 | Gasoline Res Ind And Commercia | Encapsulating method and apparatus |
| US4762719A (en) * | 1986-08-07 | 1988-08-09 | Mark Forester | Powder filled cough product |
| USH1228H (en) | 1990-10-04 | 1993-09-07 | Medicated lollipop |
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