US1046056A - Capsule. - Google Patents

Capsule. Download PDF

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Publication number
US1046056A
US1046056A US71712512A US1912717125A US1046056A US 1046056 A US1046056 A US 1046056A US 71712512 A US71712512 A US 71712512A US 1912717125 A US1912717125 A US 1912717125A US 1046056 A US1046056 A US 1046056A
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United States
Prior art keywords
capsule
liquid
medicine
syrup
capsules
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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US71712512A
Inventor
Fred H Drake
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Individual
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Individual
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Priority to US71712512A priority Critical patent/US1046056A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S264/00Plastic and nonmetallic article shaping or treating: processes
    • Y10S264/37Processes and molds for making capsules

Definitions

  • the object of the present invention is to provide an improved capsule for administering liquid medicines.
  • the invention is particularly well adapted for administering medicines for throat and bronchial affections, which must be applied direct to the parts to be treated.
  • the ordinary gelatin capsule which is intended to be dissolved in the stomach,
  • Liquid medicine administered by a capsule is much preferable to the ordinary cough drop, lozenge,
  • a capsule cancontain a far greater quantity of the medicine in proportion to its size than a cough drop or lozenge.
  • the latter are formed by a proc ess which involves cooking at a high tem perature, during which the strength of the medicine is greatly reduced.
  • capsule I mix a liquid medicine prepared according to any desired formula with sugar, and powdered acacia or gum arabic, in the proportions of 50.1bs: of syrup, 50 oz. of the liquid medicine and 4 oz. of acacia.
  • a medicine which I have used is one composed of the following. ingredients:-collinsonia 4 oz.; phytolacca 4 oz.; benzoin 8 oz.; menthol 1 oz.; capsicum 2 oz.; wintergreen 5 oz.; eucalyptus 24 oz.; turpentine 11 ⁇ oz.
  • the sugar is first cooked to a syrup, and then the medicine and acacia are added.
  • the acacia serves to keep the oils of the liquid medicine thoroughly mixed in the syrup; otherwise the oils would rise to the top of the syrup and not be equally distributed throughout.
  • the mixture is then poured troche, or the like, for the reason that not only can the contents ofithe cap--. sule be administered directly to the, affected Patented Dec. 3, 1912.
  • candies known as cordials, or'liquor drops having the form of capsules containing liquid contents have been made by using a shell'of crystallized sugar, but said candies do not have the coatingoflacacia and are not hermetically sealed and the contents will evaporate in a comparatively short time.
  • my invention. difi'ers therefrom in that not only the liquidcontents, but the shell itself, contain the medicine to be administered.
  • the great value of this invention resides in the fact that medicines can thus be carried about in a liquid form for an indefinite period, and administered immediately to the parts to be treated, merely bycrushing them in the mouth, and, further, that said capsules contain, inthe same volume, a much greater quantity of medicinal substance than cough drops, lozenges, troches, or the like.
  • I claim 2+ In combination with a'liquid substance having medicinal properties, a capsule hermetically inclosing the same and composed of said substance and others in a solid form.

Description

UNITED STATES PATENT onmcn.
FRED H. DRAKE, F OAKLAND,CALIFOBNIA.
CAPSULE.
1,046,056, Specification of Letters Patent.
No Drawing.
To all whom it my concern:
Be it known that I, FRED I-I. DRAKE, a citizen of the United States, residing at Oakland, in the county of Alameda and State of California, have invented new and useful Improvements in Capsules, of which the following is a specification.
The object of the present invention is to provide an improved capsule for administering liquid medicines.
The invention is particularly well adapted for administering medicines for throat and bronchial affections, which must be applied direct to the parts to be treated. Obviouslythe ordinary gelatin capsule, which is intended to be dissolved in the stomach,
is unsuitable for this purpose. Liquid medicine administered by a capsule is much preferable to the ordinary cough drop, lozenge,
;or the like, but a capsule cancontain a far greater quantity of the medicine in proportion to its size than a cough drop or lozenge.
Moreover, the latter are formed by a proc ess which involves cooking at a high tem perature, during which the strength of the medicine is greatly reduced. With my im-' proved capsule, as 'will hereinafter appear,
the medicinal strength of the liquid is completely retained.
Inpreparing my improved, capsule I mix a liquid medicine prepared according to any desired formula with sugar, and powdered acacia or gum arabic, in the proportions of 50.1bs: of syrup, 50 oz. of the liquid medicine and 4 oz. of acacia. Such a medicine which I have used is one composed of the following. ingredients:-collinsonia 4 oz.; phytolacca 4 oz.; benzoin 8 oz.; menthol 1 oz.; capsicum 2 oz.; wintergreen 5 oz.; eucalyptus 24 oz.; turpentine 11} oz. The sugar is first cooked to a syrup, and then the medicine and acacia are added. The acacia serves to keep the oils of the liquid medicine thoroughly mixed in the syrup; otherwise the oils would rise to the top of the syrup and not be equally distributed throughout. The mixture is then poured troche, or the like, for the reason that not only can the contents ofithe cap--. sule be administered directly to the, affected Patented Dec. 3, 1912.
Application filed August 26, 1912. Serial No. 717,125.
into starch molds, whereupon that part of the liquid coming in contact with the starch, immediately hardens, forming a shell, which envelops the liquid which has not so come in contact, and therefore remains in a liquid condition. After drying 24 hours, syrup at a proper temperature is poured over the capsules, which syrup then crystallizes. The capsules are then dried again, andare placed in a revolving kettle, where they are panned in a mixture of sugar, liquid medicine and acacia or gum arabic. The last step above described of the process of forming the capsule is extremely important, as thereby the capsule is given a tough coating which 'is impervious to air and liquid, so that my improved capsules can remain for an indefinite period unaltered. I am aware that candies known as cordials, or'liquor drops, having the form of capsules containing liquid contents have been made by using a shell'of crystallized sugar, but said candies do not have the coatingoflacacia and are not hermetically sealed and the contents will evaporate in a comparatively short time. Moreover, my invention. difi'ers therefrom in that not only the liquidcontents, but the shell itself, contain the medicine to be administered.
As' already intimated, the great value of this invention resides in the fact that medicines can thus be carried about in a liquid form for an indefinite period, and administered immediately to the parts to be treated, merely bycrushing them in the mouth, and, further, that said capsules contain, inthe same volume, a much greater quantity of medicinal substance than cough drops, lozenges, troches, or the like.
I claim 2+ In combination with a'liquid substance having medicinal properties, a capsule hermetically inclosing the same and composed of said substance and others in a solid form.
In testimony whereof I have hereunto set my hand in the presence of two subscribing witnesses.
FRED H. DRAKE. Witnesses:
FRANCIS M. WRIGHT, D. B. RICHARDS.
US71712512A 1912-08-26 1912-08-26 Capsule. Expired - Lifetime US1046056A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US71712512A US1046056A (en) 1912-08-26 1912-08-26 Capsule.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71712512A US1046056A (en) 1912-08-26 1912-08-26 Capsule.

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US1046056A true US1046056A (en) 1912-12-03

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US71712512A Expired - Lifetime US1046056A (en) 1912-08-26 1912-08-26 Capsule.

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2566645A (en) * 1941-12-12 1951-09-04 Den Bergh S En Jurgens Fabriek Method and means for making seamless capsules
US2766478A (en) * 1951-10-15 1956-10-16 Gasoline Res Ind And Commercia Encapsulating method and apparatus
US4762719A (en) * 1986-08-07 1988-08-09 Mark Forester Powder filled cough product

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2566645A (en) * 1941-12-12 1951-09-04 Den Bergh S En Jurgens Fabriek Method and means for making seamless capsules
US2766478A (en) * 1951-10-15 1956-10-16 Gasoline Res Ind And Commercia Encapsulating method and apparatus
US4762719A (en) * 1986-08-07 1988-08-09 Mark Forester Powder filled cough product

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