UA94628C2 - Humanized monoclonal antibody that binds to steap-1 and use thereof - Google Patents

Humanized monoclonal antibody that binds to steap-1 and use thereof

Info

Publication number
UA94628C2
UA94628C2 UAA200905270A UAA200905270A UA94628C2 UA 94628 C2 UA94628 C2 UA 94628C2 UA A200905270 A UAA200905270 A UA A200905270A UA A200905270 A UAA200905270 A UA A200905270A UA 94628 C2 UA94628 C2 UA 94628C2
Authority
UA
Ukraine
Prior art keywords
steap
monoclonal antibody
humanized monoclonal
binds
antibody
Prior art date
Application number
UAA200905270A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Майкл С. Деннис
Бонни РУБИНФЕЛД
Пол Полакис
Айя Якобовиц
Original Assignee
Дженентек, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дженентек, Инк. filed Critical Дженентек, Инк.
Publication of UA94628C2 publication Critical patent/UA94628C2/en

Links

Abstract

The invention relates to a humanized monoclonal antibody that specifically binds to STEAP-1. The invention further relates to a method of detecting the presence of STEAP- a biological sample, an immunoconjugate comprising the antibody, a pharmaceutical formulation, a method of inhibiting cellular proliferation etc.
UAA200905270A 2006-10-27 2007-10-26 Humanized monoclonal antibody that binds to steap-1 and use thereof UA94628C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86329506P 2006-10-27 2006-10-27

Publications (1)

Publication Number Publication Date
UA94628C2 true UA94628C2 (en) 2011-05-25

Family

ID=41232249

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200905270A UA94628C2 (en) 2006-10-27 2007-10-26 Humanized monoclonal antibody that binds to steap-1 and use thereof

Country Status (4)

Country Link
CN (1) CN101573384B (en)
SI (1) SI2061814T1 (en)
UA (1) UA94628C2 (en)
ZA (1) ZA200902161B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11180571B2 (en) 2017-04-03 2021-11-23 Hoffmann-La Roche Inc. Antibodies binding to STEAP-1

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ602840A (en) * 2010-06-03 2014-11-28 Genentech Inc Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
CA2807269A1 (en) * 2010-08-24 2012-03-01 Roche Glycart Ag Activatable bispecific antibodies
EP2621508B1 (en) * 2010-09-29 2015-08-26 Seattle Genetics, Inc. N-carboxyalkyl auristatins and the use thereof
KR20150003251A (en) * 2012-04-04 2015-01-08 가부시키가이샤 페르세우스 프로테오믹스 Conjugate Of Anti-CDH3(P-Cadherin) Antibody And Drug
EP3096797A1 (en) * 2014-01-24 2016-11-30 F. Hoffmann-La Roche AG Methods of using anti-steap1 antibodies and immunoconjugates
EP3134125B1 (en) * 2014-04-25 2019-10-09 Pierre Fabre Medicament Antibody-drug-conjugate and its use for the treatment of cancer
EP3165237B1 (en) 2015-11-03 2018-12-19 Industrial Technology Research Institute Antibody-drug conjugate (adc) and method for forming the same
CN107167541B (en) * 2017-07-08 2019-08-02 万舒(北京)医药科技有限公司 The method for measuring the DTPA-Zn in rat plasma biological sample
SG11202010443WA (en) 2018-05-09 2020-11-27 Legochem Biosciences Inc Compositions and methods related to anti-cd19 antibody drug conjugates
US20210353764A1 (en) 2018-09-26 2021-11-18 Jiangsu Hengrui Medicine Co., Ltd. Ligand-drug conjugate of exatecan analogue, preparation method therefor and application thereof
KR102503143B1 (en) * 2019-03-06 2023-02-24 주식회사 레고켐 바이오사이언스 Antibody-drug conjugate comprising antibody against human DLK1 and its use
MX2021011489A (en) 2019-04-01 2021-10-22 Jiangsu Hengrui Medicine Co Anti-claudin 18.2 antibody and application thereof.
EP3992211A4 (en) 2019-06-26 2023-01-04 Jiangsu Hengrui Medicine Co., Ltd. Anti-cea antibody and application thereof
AU2020347715A1 (en) 2019-09-18 2022-04-07 Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. Camptothecin derivative and conjugate thereof
AU2021298632A1 (en) 2020-06-30 2023-01-19 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Anti-CD70 antibody and application thereof
WO2022078425A1 (en) 2020-10-14 2022-04-21 江苏恒瑞医药股份有限公司 Anti-her3 antibody and anti-her3 antibody-drug conjugate and medical use thereof
CN112924665B (en) * 2021-02-19 2023-10-03 山东莱博生物科技有限公司 Antibody horseradish peroxidase marker and preparation and application thereof
CN113710277B (en) * 2021-07-19 2023-09-01 烟台迈百瑞国际生物医药股份有限公司 Antibody drug conjugate loaded with double toxins and application thereof
CN117295526A (en) * 2021-09-10 2023-12-26 上海药明合联生物技术有限公司 Method for preparing highly homogeneous antibody-drug conjugates of engineered antibodies
WO2024049931A1 (en) 2022-09-02 2024-03-07 Merck Sharp & Dohme Llc Exatecan-derived topoisomerase-1 inhibitors pharmaceutical compositions, and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1742966E (en) * 2004-04-22 2014-02-05 Agensys Inc Antibodies and molecules derived therefrom that bind to steap-1 proteins
CN101065151B (en) * 2004-09-23 2014-12-10 健泰科生物技术公司 Cysteine engineered antibodies and conjugates

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11180571B2 (en) 2017-04-03 2021-11-23 Hoffmann-La Roche Inc. Antibodies binding to STEAP-1
US11685790B2 (en) 2017-04-03 2023-06-27 Hoffmann-La Roche Inc. Antibodies binding to STEAP-1

Also Published As

Publication number Publication date
SI2061814T1 (en) 2012-09-28
ZA200902161B (en) 2010-06-30
CN101573384A (en) 2009-11-04
CN101573384B (en) 2013-02-20

Similar Documents

Publication Publication Date Title
UA94628C2 (en) Humanized monoclonal antibody that binds to steap-1 and use thereof
HRP20171337T1 (en) Monoclonal antibodies against claudin-18 for treatment of cancer
NO20071436L (en) Humanized Anti-5T4 Antibodies and Anti-5T4 Antibody / Calicheamicin Conjugates
NO20083891L (en) Anti-5T4 antibodies and uses thereof
NZ611269A (en) Neutralizing anti-ccl20 antibodies
MY145058A (en) Prlr-specific antibody and uses thereof
BRPI0818437A2 (en) Antibody or functional fragment of the antibody, pharmaceutical composition, use of at least one of the antibodies or functional fragments of the antibodies, and hybridoma
UA106194C2 (en) Diagnosis and treatment of cancer using anti-ereg antibody
MX2009004532A (en) Compositions and methods for binding sphingosine-1-phosphate.
IL197928A (en) Humanized monoclonal antibody that binds to steap-1, immunoconjugates and uses thereof
WO2009071696A3 (en) Humanized antibody molecules specific for il-31
TW200639182A (en) Antibody variants and uses thereof
AR057807A1 (en) ANTI-CD3 ANTIBODY FORMULATIONS
UA95958C2 (en) Antibody that binds to cd22, immunoconjugates and uses therefor
DE602006013029D1 (en) ANTI-EGFR ANTIBODY
BRPI1005176A2 (en) insulin assay, insulin assay reagent, monoclonal antibody, and method of screening monoclonal antibodies.
UA106529C2 (en) Humanized antibodies to cxcr4 for cancer treatment
WO2011053565A3 (en) Compositions and methods for detecting a tauopathy
MY146366A (en) Monoclonal antibodies, hybridoma cell lines, methods and kits for detecting phytase
UA99292C2 (en) Antibody which specifically binds to neuropilin-2b (nrp2b)
MX2009001341A (en) Ephb3-specific antibody and uses thereof.
UA109148C2 (en) Compositions based on anti-vegfr-3 antibody
BR112012002248A2 (en) antibody making method, humanized antibody making method, use of an antibody and pharmaceutical composition
UA98100C2 (en) Humanized monoclonal antibody that binds and neutralizes human nogo
UA96426C2 (en) Isolated human or humanized antibody that specifically binds to il-13