UA85512C2 - Crth2 receptor ligands for medicinal uses - Google Patents

Crth2 receptor ligands for medicinal uses

Info

Publication number
UA85512C2
UA85512C2 UAA200614018A UAA200614018A UA85512C2 UA 85512 C2 UA85512 C2 UA 85512C2 UA A200614018 A UAA200614018 A UA A200614018A UA A200614018 A UAA200614018 A UA A200614018A UA 85512 C2 UA85512 C2 UA 85512C2
Authority
UA
Ukraine
Prior art keywords
ring
monocyclic heteroaryl
membered monocyclic
crth2 receptor
fused
Prior art date
Application number
UAA200614018A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Тронд Улвен
Томас Фримурер
Эюстайн Рост
Эви Костенис
Томас Хьёгберг
Жан-Мари Ресевеур
Мари Гримструп
Original Assignee
7Тм Фарма А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0412198A external-priority patent/GB0412198D0/en
Application filed by 7Тм Фарма А/С filed Critical 7Тм Фарма А/С
Publication of UA85512C2 publication Critical patent/UA85512C2/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Compounds of formula (I) are useful for the treatment of disease responsive to modulation of CRTH2 receptor activity, such as asthma, rhinitis, allergic airway syndrome, and allergic rhinobronchitis, wherein A represents a carboxyl group -COON, or a carboxyl bioisostere; A, is I hydrogen or methyl; ring Aris an optionally substituted phenyl ring 5-or 6-membered monocyclic heteroaryl ring, in which AACHO- and L2 are linked to adjacent ring atoms; rings Are, Areach independently represent a phenyl or 5- or 6-membered monocyclic heteroaryl ring, or a bicyclic ring system consisting of a 5- or 6-membered carbocyclic or heterocyclic ring which is benz-fused or fused to a 5- or 6-membered monocyclic heteroaryl ring, said ring or ring system being optionally substituted; t is 0 or 1; L2 and L3 are linker radicals as defined in the description.(I)
UAA200614018A 2004-05-29 2005-05-30 Crth2 receptor ligands for medicinal uses UA85512C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0412198A GB0412198D0 (en) 2004-05-29 2004-05-29 Medicinal use of receptor ligands

Publications (1)

Publication Number Publication Date
UA85512C2 true UA85512C2 (en) 2009-01-26

Family

ID=38131507

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200614018A UA85512C2 (en) 2004-05-29 2005-05-30 Crth2 receptor ligands for medicinal uses

Country Status (4)

Country Link
CN (2) CN1980908A (en)
EC (2) ECSP067104A (en)
UA (1) UA85512C2 (en)
ZA (2) ZA200610598B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102016577B (en) * 2008-05-09 2015-06-17 希森美康株式会社 Blood analyzer, blood analysis method and hemolytic agent
KR20120098908A (en) 2009-12-23 2012-09-05 아이언우드 파마슈티컬스, 인코포레이티드 Crth2 modulator

Also Published As

Publication number Publication date
ZA200610597B (en) 2008-01-30
CN1980908A (en) 2007-06-13
CN1980664A (en) 2007-06-13
ZA200610598B (en) 2008-01-30
ECSP067104A (en) 2007-04-26
CN1980664B (en) 2011-02-23
ECSP067115A (en) 2007-03-29

Similar Documents

Publication Publication Date Title
EA200602290A1 (en) CRTH2 LIGANDS RECEPTOR AND THEIR APPLICATION
NO20066049L (en) Substituted thiazole acetic acids as CRTH2 ligands
Jablonowski et al. The first potent and selective non-imidazole human histamine H4 receptor antagonists
NO20084350L (en) Heterocyclic amides for use as pharmaceuticals
ATE449090T1 (en) SUBSTITUTED PIPERAZINE AND DIAZEPANDE DERIVATIVES FOR USE AS HISTAMINE H3 RECEPTOR MODULATORS
ES2174757B1 (en) EMPLOYMENT OF FIRAZOLIN DERIVATIVES IN THE PREPARATION OF A MEDICINAL PRODUCT FOR THE PREVENTION AND / OR TREATMENT OF CELLULAR PROLIFERATIVE DISEASES.
BR122017028096B8 (en) compound, pharmaceutical composition, and use of the compound
DE602006007012D1 (en) PYRIDINE DERIVATIVES AS DIPEPTEDYL-PEPTIDASE INHIBITORS
NO20050418L (en) Condensed pyridines and pyrimidines with TIE2 (TEK) activity
ATE365551T1 (en) FUSIONED HETEROARYL DERIVATIVES FOR USE AS P38 KINASE INHIBITORS FOR THE TREATMENT OF, INCLUDING RHEUMATIC ARTHRITIS
HUP0500610A2 (en) Indazoles, benzothiazoles, and benzoisothiazoles, pharmaceutical compositions comprises thereof and their uses
ATE496620T1 (en) 1H-BENZO(F)INDAZOLE-5-YL DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
ATE540021T1 (en) HYDROXANIC ACID DERIVATIVES AS INHIBITORS OF ENZYMATIC HDAC ACTIVITY
WO2007149448A3 (en) Pyrazinones as cellular proliferation inhibitors
ECSP056016A (en) NEW DERIVATIVES OF 2-PYRIDINACARBOXAMIDA
NO20063576L (en) 1,3-dioxane derivatives and analogous compounds for the treatment of obesity and diabetes
EA200702058A1 (en) NEW PHARMACEUTICAL COMPOUNDS
HRP20041137B1 (en) Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides
MX2009010909A (en) Phthalazinone derivatives and their use as medicament to treat cancer.
NO20082917L (en) Oxadiazole derivatives with CRTH2 receptor activity
MY148988A (en) Terphenyl derivatives for treatment of alzheimer's disease
TN2011000380A1 (en) Triazolopyridine derivatives as p38 map kinase inhibitors
AR040626A1 (en) USEFUL QUINOLINE DERIVATIVES AS NEUROPEPTIDE RECEIVER AND (NPY)
DE602008001725D1 (en) 1- (1-BENZYLPIPERIDIN-4-YL) BENZIMIDAZOLE-5-CARBOXYLENE DERIVATIVES FOR THE TREATMENT OF DIABETES MELLITUS
ATE469128T1 (en) INDOLES SUITABLE FOR THE TREATMENT OF ANDROGEN RECEPTOR-RELATED DISEASES