UA32423C2 - Тетрагідроізохінолінові сполуки, які мають антагоністичну активність у відношенні до допамінових рецепторів d1 і d2, спосіб їх одержання, фармацевтична композиція на їх основі і спосіб зв'язування допамінових рецепторів d1 і d2 - Google Patents
Тетрагідроізохінолінові сполуки, які мають антагоністичну активність у відношенні до допамінових рецепторів d1 і d2, спосіб їх одержання, фармацевтична композиція на їх основі і спосіб зв'язування допамінових рецепторів d1 і d2Info
- Publication number
- UA32423C2 UA32423C2 UA94005505A UA94005505A UA32423C2 UA 32423 C2 UA32423 C2 UA 32423C2 UA 94005505 A UA94005505 A UA 94005505A UA 94005505 A UA94005505 A UA 94005505A UA 32423 C2 UA32423 C2 UA 32423C2
- Authority
- UA
- Ukraine
- Prior art keywords
- compounds
- dophamine
- receptor
- synthesis
- binding
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000003039 tetrahydroisoquinolinyl group Chemical class C1(NCCC2=CC=CC=C12)* 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 229960003638 dopamine Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 abstract 1
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 abstract 1
- 208000028698 Cognitive impairment Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 206010043118 Tardive Dyskinesia Diseases 0.000 abstract 1
- 230000036592 analgesia Effects 0.000 abstract 1
- 208000015802 attention deficit-hyperactivity disease Diseases 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 206010013663 drug dependence Diseases 0.000 abstract 1
- 208000035231 inattentive type attention deficit hyperactivity disease Diseases 0.000 abstract 1
- 208000011117 substance-related disease Diseases 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919127306A GB9127306D0 (en) | 1991-12-23 | 1991-12-23 | Therapeutic agents |
| PCT/EP1992/002900 WO1993013073A1 (en) | 1991-12-23 | 1992-12-12 | Substituted tetrahydroisoquinolines and their use as therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA32423C2 true UA32423C2 (uk) | 2000-12-15 |
Family
ID=47521612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA94005505A UA32423C2 (uk) | 1991-12-23 | 1992-12-12 | Тетрагідроізохінолінові сполуки, які мають антагоністичну активність у відношенні до допамінових рецепторів d1 і d2, спосіб їх одержання, фармацевтична композиція на їх основі і спосіб зв'язування допамінових рецепторів d1 і d2 |
Country Status (5)
| Country | Link |
|---|---|
| KR (1) | KR100248558B1 (enrdf_load_stackoverflow) |
| MY (1) | MY108027A (enrdf_load_stackoverflow) |
| TW (1) | TW300889B (enrdf_load_stackoverflow) |
| UA (1) | UA32423C2 (enrdf_load_stackoverflow) |
| YU (1) | YU48648B (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20250111564A (ko) | 2024-01-15 | 2025-07-22 | 우석대학교 산학협력단 | 도심항공 모빌리티와 버티포트를 이용한 플라잉 플래너 시스템 및 방법 |
-
1992
- 1992-12-12 KR KR1019940702189A patent/KR100248558B1/ko not_active Expired - Fee Related
- 1992-12-12 UA UA94005505A patent/UA32423C2/uk unknown
- 1992-12-22 MY MYPI92002362A patent/MY108027A/en unknown
- 1992-12-23 YU YU110692A patent/YU48648B/sh unknown
-
1993
- 1993-06-22 TW TW082104999A patent/TW300889B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| YU48648B (sh) | 1999-06-15 |
| TW300889B (enrdf_load_stackoverflow) | 1997-03-21 |
| MY108027A (en) | 1996-07-30 |
| KR100248558B1 (ko) | 2000-04-01 |
| YU110692A (sh) | 1996-01-08 |
| KR940703812A (ko) | 1994-12-12 |
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