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Application filed by Амджен Инк.filedCriticalАмджен Инк.
Priority claimed from PCT/US2008/003119external-prioritypatent/WO2008109167A2/en
Publication of UA101609C2publicationCriticalpatent/UA101609C2/en
Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Peptides Or Proteins
(AREA)
Abstract
The invention relates to isolated proteins of soluble receptor activin IIB, able to bind activin A receptor, myostatine or GDF-11, and to inhibit activity thereof. The invention also relates to vector and host cell, composition containing isolated protein, and to the method for treatment of amyotrophy and other diseases and defects connected with activin A receptor, myostatine or GDF-11.
UAA200910064A2007-03-062008-03-06Modified polypeptides of activin receptor and using thereof
UA101609C2
(en)
Isolated bid polypeptides, polynucleotides encoding same and antibodies directed thereagainst and methods of using same for inducing cell cycle arrest or apoptosis