TWI889740B - 水性組成物 - Google Patents

水性組成物

Info

Publication number
TWI889740B
TWI889740B TW109146300A TW109146300A TWI889740B TW I889740 B TWI889740 B TW I889740B TW 109146300 A TW109146300 A TW 109146300A TW 109146300 A TW109146300 A TW 109146300A TW I889740 B TWI889740 B TW I889740B
Authority
TW
Taiwan
Prior art keywords
aqueous composition
degatinib
salts
mass
salt
Prior art date
Application number
TW109146300A
Other languages
English (en)
Chinese (zh)
Other versions
TW202135821A (zh
Inventor
西本明功
喜多亜希子
林紗衣子
Original Assignee
日商樂敦製藥股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日商樂敦製藥股份有限公司 filed Critical 日商樂敦製藥股份有限公司
Publication of TW202135821A publication Critical patent/TW202135821A/zh
Application granted granted Critical
Publication of TWI889740B publication Critical patent/TWI889740B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
TW109146300A 2019-12-27 2020-12-25 水性組成物 TWI889740B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019239599 2019-12-27
JPJP2019-239599 2019-12-27

Publications (2)

Publication Number Publication Date
TW202135821A TW202135821A (zh) 2021-10-01
TWI889740B true TWI889740B (zh) 2025-07-11

Family

ID=76574720

Family Applications (2)

Application Number Title Priority Date Filing Date
TW109146300A TWI889740B (zh) 2019-12-27 2020-12-25 水性組成物
TW114121991A TW202541813A (zh) 2019-12-27 2020-12-25 水性組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW114121991A TW202541813A (zh) 2019-12-27 2020-12-25 水性組成物

Country Status (6)

Country Link
US (1) US20230101139A1 (https=)
EP (2) EP4674401A3 (https=)
JP (2) JP7617031B2 (https=)
CN (2) CN119367282A (https=)
TW (2) TWI889740B (https=)
WO (1) WO2021132598A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220044288A (ko) * 2019-08-07 2022-04-07 로토 세이야쿠 가부시키가이샤 누액 분비 촉진용 안과 조성물
AU2021318236A1 (en) * 2020-07-30 2023-03-09 Rohto Pharmaceutical Co., Ltd. Aqueous composition
WO2024204749A1 (ja) * 2023-03-31 2024-10-03 ロート製薬株式会社 眼科組成物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015060208A1 (ja) * 2013-10-21 2015-04-30 日本たばこ産業株式会社 眼疾患の治療剤又は予防剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5575100B2 (ja) * 2004-12-28 2014-08-20 ロート製薬株式会社 プラノプロフェン含有組成物
US8541426B2 (en) * 2007-07-11 2013-09-24 Pfizer Inc. Pharmaceutical compositions and methods of treating dry eye disorders
TWI466885B (zh) * 2009-07-31 2015-01-01 Japan Tobacco Inc 含氮螺環化合物及其醫藥用途
HK1251223A1 (en) 2015-07-07 2019-01-25 Japan Tobacco, Inc. Method for producing 7h-pyrrolo[2, 3-d]pyrimidine derivative and intermediate thereof
KR102728341B1 (ko) * 2015-09-24 2024-11-11 레오 파마 에이/에스 원형탈모증의 치료
KR102702286B1 (ko) 2016-12-21 2024-09-04 니뽄 다바코 산교 가부시키가이샤 7H-피롤로[2,3-d]피리미딘 유도체의 제조 방법 및 그의 공결정
KR20220044288A (ko) * 2019-08-07 2022-04-07 로토 세이야쿠 가부시키가이샤 누액 분비 촉진용 안과 조성물
JP7722931B2 (ja) * 2019-12-27 2025-08-13 ロート製薬株式会社 水性組成物
US20230285564A1 (en) * 2020-07-30 2023-09-14 Rohto Pharmaceutical Co., Ltd. Aqueous Composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015060208A1 (ja) * 2013-10-21 2015-04-30 日本たばこ産業株式会社 眼疾患の治療剤又は予防剤

Also Published As

Publication number Publication date
JPWO2021132598A1 (https=) 2021-07-01
TW202135821A (zh) 2021-10-01
US20230101139A1 (en) 2023-03-30
EP4070796B1 (en) 2025-12-24
EP4674401A2 (en) 2026-01-07
CN114867480A (zh) 2022-08-05
EP4674401A3 (en) 2026-02-25
TW202541813A (zh) 2025-11-01
EP4070796A1 (en) 2022-10-12
EP4070796A4 (en) 2024-01-17
JP2025036714A (ja) 2025-03-14
JP7617031B2 (ja) 2025-01-17
CN119367282A (zh) 2025-01-28
EP4070796C0 (en) 2025-12-24
WO2021132598A1 (ja) 2021-07-01

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