TWI856115B - 惡性腫瘤之治療方法 - Google Patents
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
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- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| JP2019-115496 | 2019-06-21 | ||
| JP2019115496 | 2019-06-21 |
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| TW202114691A TW202114691A (zh) | 2021-04-16 |
| TWI856115B true TWI856115B (zh) | 2024-09-21 |
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| TW109120904A TWI856115B (zh) | 2019-06-21 | 2020-06-19 | 惡性腫瘤之治療方法 |
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| EP (1) | EP3988175A4 (https=) |
| JP (1) | JP7574184B2 (https=) |
| KR (1) | KR20220024821A (https=) |
| AU (1) | AU2020297166A1 (https=) |
| MA (1) | MA56549A (https=) |
| TW (1) | TWI856115B (https=) |
| WO (1) | WO2020256096A1 (https=) |
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| EP3424505A4 (en) | 2016-03-04 | 2019-10-16 | Taiho Pharmaceutical Co., Ltd. | PREPARATION AND COMPOSITION FOR THE TREATMENT OF MALIGNANT TUMORS |
| US11883404B2 (en) | 2016-03-04 | 2024-01-30 | Taiho Pharmaceuticals Co., Ltd. | Preparation and composition for treatment of malignant tumors |
| SG11202008435SA (en) | 2018-03-19 | 2020-10-29 | Taiho Pharmaceutical Co Ltd | Pharmaceutical composition including sodium alkyl sulfate |
| EP4284378A4 (en) * | 2021-02-01 | 2024-12-25 | Taiho Pharmaceutical Co., Ltd. | Ptentreating cancer in patient with pten inactivating mutation |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201408671A (zh) * | 2012-07-02 | 2014-03-01 | Taiho Pharmaceutical Co Ltd | 利用咪唑并□化合物之抗腫瘤效果增強劑 |
| TW201733590A (zh) * | 2016-03-04 | 2017-10-01 | 大鵬藥品工業股份有限公司 | 惡性腫瘤治療用製劑及組合物 |
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| KR101658274B1 (ko) | 2011-04-06 | 2016-09-22 | 다이호야쿠힌고교 가부시키가이샤 | 신규 이미다조 옥사진 화합물 또는 그의 염 |
| DK2657233T3 (da) | 2012-01-19 | 2014-09-22 | Taiho Pharmaceutical Co Ltd | 3,5-disubstitueret alkynylbenzenforbindelse og salt deraf |
| JP6289459B2 (ja) | 2013-06-20 | 2018-03-07 | 大鵬薬品工業株式会社 | ＰＨＬＤＡ１又はＰＩＫ３Ｃ２Ｂの発現に基づくＰＩ３Ｋ／ＡＫＴ／ｍＴＯＲ阻害剤の治療効果の予測方法 |
| CN111943962A (zh) * | 2015-02-27 | 2020-11-17 | 大鹏药品工业株式会社 | 咪唑并噁嗪晶体、含有所述晶体的药物组合物和制备所述晶体的方法 |
| US11883404B2 (en) | 2016-03-04 | 2024-01-30 | Taiho Pharmaceuticals Co., Ltd. | Preparation and composition for treatment of malignant tumors |
| EP4093406A4 (en) * | 2020-01-24 | 2024-02-28 | Taiho Pharmaceutical Co., Ltd. | IMPROVEMENT OF THE ANTI-TUMORAL ACTIVITY OF SHP2 INHIBITOR PYRIMIDINONE IN COMBINATION WITH NEW ANTI-CANCER DRUGS AGAINST CANCER |
| EP4284378A4 (en) * | 2021-02-01 | 2024-12-25 | Taiho Pharmaceutical Co., Ltd. | Ptentreating cancer in patient with pten inactivating mutation |
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2020
- 2020-06-19 KR KR1020227002122A patent/KR20220024821A/ko not_active Withdrawn
- 2020-06-19 AU AU2020297166A patent/AU2020297166A1/en not_active Abandoned
- 2020-06-19 TW TW109120904A patent/TWI856115B/zh active
- 2020-06-19 EP EP20827927.3A patent/EP3988175A4/en active Pending
- 2020-06-19 WO PCT/JP2020/024113 patent/WO2020256096A1/ja not_active Ceased
- 2020-06-19 JP JP2021526910A patent/JP7574184B2/ja active Active
- 2020-06-19 US US17/620,419 patent/US20220354858A1/en active Pending
- 2020-06-19 MA MA056549A patent/MA56549A/fr unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201408671A (zh) * | 2012-07-02 | 2014-03-01 | Taiho Pharmaceutical Co Ltd | 利用咪唑并□化合物之抗腫瘤效果增強劑 |
| TW201733590A (zh) * | 2016-03-04 | 2017-10-01 | 大鵬藥品工業股份有限公司 | 惡性腫瘤治療用製劑及組合物 |
Non-Patent Citations (1)
| Title |
|---|
| 期刊 Brown et al. Maximising the potential of AKT inhibitors as anti-cancer treatments Pharmacology & Therapeutics 172 2017 101-115 * |
Also Published As
| Publication number | Publication date |
|---|---|
| TW202114691A (zh) | 2021-04-16 |
| US20220354858A1 (en) | 2022-11-10 |
| JPWO2020256096A1 (https=) | 2020-12-24 |
| WO2020256096A1 (ja) | 2020-12-24 |
| MA56549A (fr) | 2022-04-27 |
| AU2020297166A1 (en) | 2022-02-17 |
| EP3988175A4 (en) | 2023-06-28 |
| KR20220024821A (ko) | 2022-03-03 |
| JP7574184B2 (ja) | 2024-10-28 |
| EP3988175A1 (en) | 2022-04-27 |
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