TWI293253B - Medical devices incorporating deuterated rapamycin for controlled delivery thereof - Google Patents

Medical devices incorporating deuterated rapamycin for controlled delivery thereof Download PDF

Info

Publication number
TWI293253B
TWI293253B TW92131045A TW92131045A TWI293253B TW I293253 B TWI293253 B TW I293253B TW 92131045 A TW92131045 A TW 92131045A TW 92131045 A TW92131045 A TW 92131045A TW I293253 B TWI293253 B TW I293253B
Authority
TW
Taiwan
Prior art keywords
medical devices
controlled delivery
devices incorporating
deuterated rapamycin
incorporating deuterated
Prior art date
Application number
TW92131045A
Other versions
TW200418538A (en
Inventor
Joseph Koziak
Selvaraj Naicker
Randall W Yatscoff
Robert T Foster
Original Assignee
Isotechnika Internat Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US10/301,504 priority Critical patent/US6884429B2/en
Application filed by Isotechnika Internat Inc filed Critical Isotechnika Internat Inc
Publication of TW200418538A publication Critical patent/TW200418538A/en
Application granted granted Critical
Publication of TWI293253B publication Critical patent/TWI293253B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow
TW92131045A 1997-09-05 2003-11-06 Medical devices incorporating deuterated rapamycin for controlled delivery thereof TWI293253B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US10/301,504 US6884429B2 (en) 1997-09-05 2002-11-20 Medical devices incorporating deuterated rapamycin for controlled delivery thereof

Publications (2)

Publication Number Publication Date
TW200418538A TW200418538A (en) 2004-10-01
TWI293253B true TWI293253B (en) 2008-02-11

Family

ID=32324552

Family Applications (1)

Application Number Title Priority Date Filing Date
TW92131045A TWI293253B (en) 1997-09-05 2003-11-06 Medical devices incorporating deuterated rapamycin for controlled delivery thereof

Country Status (11)

Country Link
US (1) US6884429B2 (en)
EP (1) EP1562654A1 (en)
JP (1) JP2006512943A (en)
KR (1) KR20050071702A (en)
AU (1) AU2003287677A1 (en)
BR (1) BR0315700A (en)
CA (1) CA2505080A1 (en)
MX (1) MXPA05005315A (en)
NZ (1) NZ539470A (en)
TW (1) TWI293253B (en)
WO (1) WO2004045668A1 (en)

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Also Published As

Publication number Publication date
JP2006512943A (en) 2006-04-20
MXPA05005315A (en) 2005-10-26
EP1562654A1 (en) 2005-08-17
CA2505080A1 (en) 2004-06-03
TW200418538A (en) 2004-10-01
KR20050071702A (en) 2005-07-07
US6884429B2 (en) 2005-04-26
BR0315700A (en) 2005-09-06
US20030130206A1 (en) 2003-07-10
NZ539470A (en) 2006-11-30
WO2004045668A1 (en) 2004-06-03
AU2003287677A1 (en) 2004-06-15

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