TW221689B - - Google Patents

Info

Publication number
TW221689B
TW221689B TW081106619A TW81106619A TW221689B TW 221689 B TW221689 B TW 221689B TW 081106619 A TW081106619 A TW 081106619A TW 81106619 A TW81106619 A TW 81106619A TW 221689 B TW221689 B TW 221689B
Authority
TW
Taiwan
Application number
TW081106619A
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of TW221689B publication Critical patent/TW221689B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
TW081106619A 1991-08-27 1992-08-21 TW221689B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21562191 1991-08-27

Publications (1)

Publication Number Publication Date
TW221689B true TW221689B (zh) 1994-03-11

Family

ID=16675440

Family Applications (1)

Application Number Title Priority Date Filing Date
TW081106619A TW221689B (zh) 1991-08-27 1992-08-21

Country Status (7)

Country Link
US (1) US5422360A (zh)
EP (1) EP0531812A1 (zh)
KR (1) KR930004286A (zh)
CN (1) CN1034864C (zh)
AU (1) AU649158B2 (zh)
CA (1) CA2077032A1 (zh)
TW (1) TW221689B (zh)

Families Citing this family (21)

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Publication number Priority date Publication date Assignee Title
BR9307141A (pt) * 1992-09-29 1999-03-30 Inhale Therapeutic Syst Processo para a liberação sistência pulsátil de um fragmento ativo de hormônio de paratiróide (PTH) para um hospedeiro mamífero e para um paciente e composição farmacêutica
DE69429641T2 (de) * 1993-02-26 2002-08-29 Otsuka Pharma Co Ltd Thiazole oder imidazole derivate als maillard reaktion inhibitoren
US20030113273A1 (en) * 1996-06-17 2003-06-19 Patton John S. Methods and compositions for pulmonary delivery of insulin
GB2288732B (en) * 1994-04-13 1998-04-29 Quadrant Holdings Cambridge Pharmaceutical compositions
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
EP0912523A1 (en) * 1996-05-21 1999-05-06 PHARMACIA & UPJOHN COMPANY Aminoguanidine carboxylate lactams for the treatment of non-insulin-dependent diabetes mellitus
AU6518598A (en) * 1997-03-28 1998-10-22 Otsuka Pharmaceutical Co., Ltd. Age production inhibitory composition comprising a maillard reaction inhibitor and vitamin b6
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
WO2001085136A2 (en) 2000-05-10 2001-11-15 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
TWI324518B (en) 2001-12-19 2010-05-11 Nektar Therapeutics Pulmonary delivery of aminoglycosides
USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
PL1689726T3 (pl) 2003-11-21 2011-05-31 Actelion Pharmaceuticals Ltd Pochodne 5-(benz-(z)-ylideno)tiazolidyn-4-onu jako środki immunosupresyjne
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
DK2094676T3 (da) * 2006-11-23 2013-06-10 Actelion Pharmaceuticals Ltd Ny fremgangsmåde til fremstillingen af 2-iminothiazolidin-4-on-derivater
US9340518B2 (en) 2012-08-17 2016-05-17 Actelion Pharmaceuticals Ltd. Process for the preparation of (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropdxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process
CN106620745B (zh) * 2015-11-02 2019-10-11 中国石油化工股份有限公司 一种降低培养基灭菌过程中的美拉德反应的方法
CN107522311A (zh) * 2017-10-19 2017-12-29 王云龙 一种净水机
CN114315753B (zh) * 2020-09-30 2023-11-21 烟台药物研究所 一种化合物、其合成方法与应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE185346C (zh) *
DE381628C (de) * 1923-09-22 Gegauf & Co Nadelkluppe fuer Handstickmaschinen
GB132914A (zh) *
GB181779A (en) * 1921-02-19 1922-06-19 Henry Ramsden Improvements in covers or gaiters for laminated vehicle springs
DE929549C (de) * 1951-11-29 1955-08-01 Hoechst Ag Verfahren zur Herstellung substituierter Pseudothiohydantoine und ihrer Hydrohalogenide
DE932674C (de) * 1952-12-06 1955-09-05 Hoechst Ag Verfahren zur Herstellung von N-Alkoxyphenyl-pseudothiohydantoinen
US2739971A (en) * 1954-03-29 1956-03-27 Eastman Kodak Co 5-benzal-3-n-cetyl-2-phenylimino-4-thiazolidone
DE1038050B (de) * 1955-11-17 1958-09-04 Farmaceutici Italia S A Soc Verfahren zur Herstellung von 5-(3', 4'-Dioxybenzyliden)-Derivaten heterocyclischer Verbindungen
FR1604530A (zh) * 1967-06-06 1971-11-29
US3641019A (en) * 1968-08-30 1972-02-08 Dow Chemical Co Thiazolo-as-triazines
AR204619A1 (es) * 1973-02-13 1976-02-20 Ciba Geigy Ag Procedimiento para la elaboracion de un nuevo derivado de 2,2-azina-2,4-tiazolidindiona
US4402964A (en) * 1981-11-16 1983-09-06 Mcneilab, Inc. N-Aryl-N'-(3-methyl or ethyl-4-oxothiazolidinylidene)ureas useful for the treatment of epilepsy
DE3146299A1 (de) * 1981-11-17 1983-06-01 Schering Ag, 1000 Berlin Und 4619 Bergkamen Thiazolo- und (1,3)thiazino(2,3-c)(1,2,4)triazinone mit selektiver herbizider wirkung sowie verfahren zur herstellung dieser verbindungen
DE3302413A1 (de) * 1983-01-21 1984-07-26 Schering AG, 1000 Berlin und 4709 Bergkamen Triazinone, verfahren zur herstellung dieser verbindungen sowie diese enthaltende mittel mit selektiver herbizider wirkung
GB8311443D0 (en) * 1983-04-27 1983-06-02 Smith Kline French Lab Chemical compounds
US4908446A (en) * 1985-11-14 1990-03-13 The Rockefeller University Inhibitors of nonenzymatic cross-linking
US4758583A (en) * 1984-03-19 1988-07-19 The Rockefeller University Method and agents for inhibiting protein aging
DE3446812A1 (de) * 1984-12-21 1986-06-26 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
US4657922A (en) * 1985-05-24 1987-04-14 Mcneilab, Inc. Anxiolytic 4,5-dihydro-4-oxo-1H-imidazol-2-yl urea derivatives
JPS6456614A (en) * 1987-08-27 1989-03-03 Ono Pharmaceutical Co Maillard reaction inhibitor
JPS6483059A (en) * 1987-09-25 1989-03-28 Ono Pharmaceutical Co Guanidine derivative, its production and maillard reaction inhibitor containing said derivative as active component
DE3841879A1 (de) * 1988-12-13 1990-06-21 Boehringer Mannheim Gmbh Neue imidazolidin-derivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
US4957936A (en) * 1989-02-01 1990-09-18 Nippon Zoki Pharmaceutical Co., Ltd. Glycocyamidine derivatives

Also Published As

Publication number Publication date
CN1069728A (zh) 1993-03-10
US5422360A (en) 1995-06-06
AU2131192A (en) 1993-03-04
CA2077032A1 (en) 1993-02-28
CN1034864C (zh) 1997-05-14
EP0531812A1 (en) 1993-03-17
AU649158B2 (en) 1994-05-12
KR930004286A (ko) 1993-03-22

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