TW202334120A - 經取代之哌啶化合物之結晶以及經取代之哌啶化合物之鹽及其等之結晶 - Google Patents

經取代之哌啶化合物之結晶以及經取代之哌啶化合物之鹽及其等之結晶 Download PDF

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Publication number
TW202334120A
TW202334120A TW112101371A TW112101371A TW202334120A TW 202334120 A TW202334120 A TW 202334120A TW 112101371 A TW112101371 A TW 112101371A TW 112101371 A TW112101371 A TW 112101371A TW 202334120 A TW202334120 A TW 202334120A
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TW
Taiwan
Prior art keywords
ppm
cyclopropyl
acetamide
azabicyclo
octane
Prior art date
Application number
TW112101371A
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English (en)
Chinese (zh)
Inventor
櫛田郁雄
伊藤洋子
安井崇
福山尚
佐藤信明
淺羽太郎
Original Assignee
日商衛材R&D企管股份有限公司
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Publication date
Application filed by 日商衛材R&D企管股份有限公司 filed Critical 日商衛材R&D企管股份有限公司
Publication of TW202334120A publication Critical patent/TW202334120A/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
TW112101371A 2022-01-14 2023-01-12 經取代之哌啶化合物之結晶以及經取代之哌啶化合物之鹽及其等之結晶 TW202334120A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2022-004608 2022-01-14
JP2022004608 2022-01-14

Publications (1)

Publication Number Publication Date
TW202334120A true TW202334120A (zh) 2023-09-01

Family

ID=87279104

Family Applications (1)

Application Number Title Priority Date Filing Date
TW112101371A TW202334120A (zh) 2022-01-14 2023-01-12 經取代之哌啶化合物之結晶以及經取代之哌啶化合物之鹽及其等之結晶

Country Status (10)

Country Link
US (1) US20250051322A1 (https=)
EP (1) EP4438602A4 (https=)
JP (1) JPWO2023136279A1 (https=)
KR (1) KR20240134870A (https=)
CN (1) CN118451076A (https=)
AU (1) AU2023206823A1 (https=)
CA (1) CA3243267A1 (https=)
MX (1) MX2024008024A (https=)
TW (1) TW202334120A (https=)
WO (1) WO2023136279A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7591592B2 (ja) * 2022-01-14 2024-11-28 エーザイ・アール・アンド・ディー・マネジメント株式会社 置換ピペリジン化合物を含有する医薬

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG34208A1 (en) 1995-03-01 1996-12-06 Guy Andrew Vaz Blast and fragment resistant polyurethane boot sole for safety footwear
EP0828751A4 (en) 1995-05-05 1999-01-20 Human Genome Sciences Inc HUMAN NEUROPEPTIDE RECEPTOR
US6309854B1 (en) 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US6159605A (en) 1997-02-18 2000-12-12 Dainichiseika Color & Chemicals Mfg. Co., Ltd. Ink-jet recording sheet
US5935814A (en) 1997-04-30 1999-08-10 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72Y receptor
US6020157A (en) 1997-04-30 2000-02-01 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72X receptor
US6166193A (en) 1997-07-25 2000-12-26 Board Of Regents, University Of Texas System Polynucleotides encoding MY1 receptor
KR100327888B1 (ko) 1999-07-14 2002-03-09 정숭렬 도로포장 파손촉진 시험장치의 무선제어 시스템
TW201444849A (zh) * 2013-03-13 2014-12-01 Janssen Pharmaceutica Nv 經取代的7-氮雜雙環類及其作為食慾激素受體調節劑之用途
EP3896060B1 (en) * 2018-12-12 2023-08-16 Takeda Pharmaceutical Company Limited Heterocyclic compound
TWI888599B (zh) * 2020-07-17 2025-07-01 日商衛材R&D企管股份有限公司 取代哌啶化合物及其用途

Also Published As

Publication number Publication date
CN118451076A (zh) 2024-08-06
EP4438602A1 (en) 2024-10-02
CA3243267A1 (en) 2025-04-10
US20250051322A1 (en) 2025-02-13
KR20240134870A (ko) 2024-09-10
WO2023136279A1 (ja) 2023-07-20
AU2023206823A1 (en) 2024-07-11
MX2024008024A (es) 2024-07-15
JPWO2023136279A1 (https=) 2023-07-20
EP4438602A4 (en) 2025-11-19

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