TW202305127A - 用於改良磷酸轉移酶之材料及方法 - Google Patents

用於改良磷酸轉移酶之材料及方法 Download PDF

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Publication number
TW202305127A
TW202305127A TW111114949A TW111114949A TW202305127A TW 202305127 A TW202305127 A TW 202305127A TW 111114949 A TW111114949 A TW 111114949A TW 111114949 A TW111114949 A TW 111114949A TW 202305127 A TW202305127 A TW 202305127A
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Taiwan
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amino acid
seq
npt
cells
nucleic acid
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TW111114949A
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English (en)
Chinese (zh)
Inventor
威廉 勞埃德 三世 佩利
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美商健生生物科技公司
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Publication of TW202305127A publication Critical patent/TW202305127A/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01095—Kanamycin kinase (2.7.1.95), i.e. neomycin-kanamycin phosphotransferase

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TW111114949A 2021-04-21 2022-04-20 用於改良磷酸轉移酶之材料及方法 TW202305127A (zh)

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US202163177767P 2021-04-21 2021-04-21
US202163177749P 2021-04-21 2021-04-21
US202163177759P 2021-04-21 2021-04-21
US202163177744P 2021-04-21 2021-04-21
US202163177746P 2021-04-21 2021-04-21
US202163177753P 2021-04-21 2021-04-21
US202163177764P 2021-04-21 2021-04-21
US202163177739P 2021-04-21 2021-04-21
US63/177,753 2021-04-21
US63/177,749 2021-04-21
US63/177,759 2021-04-21
US63/177,767 2021-04-21
US63/177,746 2021-04-21
US63/177,764 2021-04-21
US63/177,739 2021-04-21
US63/177,744 2021-04-21

Publications (1)

Publication Number Publication Date
TW202305127A true TW202305127A (zh) 2023-02-01

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TW111114949A TW202305127A (zh) 2021-04-21 2022-04-20 用於改良磷酸轉移酶之材料及方法

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US (1) US20240191215A1 (https=)
EP (1) EP4326747A4 (https=)
JP (1) JP2024516153A (https=)
KR (1) KR20230173159A (https=)
AU (1) AU2022261882A1 (https=)
BR (1) BR112023021960A2 (https=)
CA (1) CA3217224A1 (https=)
IL (1) IL307870A (https=)
MX (1) MX2023012514A (https=)
TW (1) TW202305127A (https=)
WO (1) WO2022226005A1 (https=)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7344886B2 (en) * 2002-11-29 2008-03-18 Boehringer Ingelheim Pharma Gmbh & Co., Kg Neomycin-phosphotransferase-genes and methods for the selection of recombinant cells producing high levels of a desired gene product
KR101149777B1 (ko) * 2002-11-29 2012-06-11 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 신규한 네오마이신 포스포트랜스퍼라제 유전자 및 고생산성 재조합 세포의 선별 방법
US20080124760A1 (en) * 2006-07-26 2008-05-29 Barbara Enenkel Regulatory Nucleic Acid Elements
EP1975228A1 (en) * 2007-03-28 2008-10-01 Fachhochschule Mannheim Polynucleotides for enhancing expression of a polynucleotide of interest
AU2011342162B2 (en) * 2010-12-15 2017-04-20 Kyowa Kirin Co., Ltd. Method for producing proteins
US11389531B2 (en) * 2017-12-19 2022-07-19 Janssen Sciences Ireland Unlimited Company Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines

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Publication number Publication date
CA3217224A1 (en) 2022-10-27
US20240191215A1 (en) 2024-06-13
IL307870A (en) 2023-12-01
JP2024516153A (ja) 2024-04-12
WO2022226005A1 (en) 2022-10-27
MX2023012514A (es) 2024-01-05
EP4326747A1 (en) 2024-02-28
EP4326747A4 (en) 2025-06-11
AU2022261882A1 (en) 2023-12-07
BR112023021960A2 (pt) 2023-12-26
KR20230173159A (ko) 2023-12-26
AU2022261882A9 (en) 2023-12-14

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