TR201909589T4 - Solunum hastalıklarının aerosol terapisinde kullanıma yönelik inhalasyon cihazı. - Google Patents

Solunum hastalıklarının aerosol terapisinde kullanıma yönelik inhalasyon cihazı. Download PDF

Info

Publication number
TR201909589T4
TR201909589T4 TR2019/09589T TR201909589T TR201909589T4 TR 201909589 T4 TR201909589 T4 TR 201909589T4 TR 2019/09589 T TR2019/09589 T TR 2019/09589T TR 201909589 T TR201909589 T TR 201909589T TR 201909589 T4 TR201909589 T4 TR 201909589T4
Authority
TR
Turkey
Prior art keywords
inhalation device
inhalation
respiratory diseases
kit
aerosol therapy
Prior art date
Application number
TR2019/09589T
Other languages
English (en)
Inventor
Allosery Koen
Huber Martin
Kolb Tobias
Müllinger Bernhard
Schick Juliane
Depla Erik
Original Assignee
Ablynx Nv
Vectura Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ablynx Nv, Vectura Gmbh filed Critical Ablynx Nv
Publication of TR201909589T4 publication Critical patent/TR201909589T4/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • A61M11/003Particle size control by passing the aerosol trough sieves or filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/006Sprayers or atomisers specially adapted for therapeutic purposes operated by applying mechanical pressure to the liquid to be sprayed or atomised
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A61M11/042Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0085Inhalators using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0091Inhalators mechanically breath-triggered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/02Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • A61M15/025Bubble jet droplet ejection devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/06Inhaling appliances shaped like cigars, cigarettes or pipes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20Valves specially adapted to medical respiratory devices
    • A61M16/201Controlled valves
    • A61M16/202Controlled valves electrically actuated
    • A61M16/203Proportional
    • A61M16/204Proportional used for inhalation control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20Valves specially adapted to medical respiratory devices
    • A61M16/201Controlled valves
    • A61M16/202Controlled valves electrically actuated
    • A61M16/203Proportional
    • A61M16/205Proportional used for exhalation control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20Valves specially adapted to medical respiratory devices
    • A61M16/208Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0208Oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/025Helium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/02Gases
    • A61M2202/0266Nitrogen (N)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/11Laminar flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2240/00Specially adapted for neonatal use
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mechanical Engineering (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Buluş inhalasyon cihazı, inhalasyon cihazının bir kiti ve bir kombinasyonu ve bir farmasötik bileşim içeren bir inhalasyon cihazı, bir tertibat veya inhalasyon sistemi sağlamaktadır. Buna ek olarak, buluş, cihazın, tertibatın, kitin ve kombinasyonun kullanımlarını sağlamaktadır. Cihaz, özellikle bebekler, infantlar veya yürümeye başlayan çocukları kapsayan pediyatrik hastalar için terapötik aerosollerin uygulanmasına yönelik uyarlanmaktadır. Bu, bir yanal açıklık ile inhalasyon cihazının bir akım kanalı içine yerleştirilebilen bir titreşimli gözcük aerosol üretici ve bir valfli yüz maskesi içermektedir. Cihaz, oksijen gibi bir gazın bir düşük akım oranında akım kanalı içine alınabilmesiyle bir gaz kaynağına bağlanabilmektedir.
TR2019/09589T 2014-10-10 2015-10-09 Solunum hastalıklarının aerosol terapisinde kullanıma yönelik inhalasyon cihazı. TR201909589T4 (tr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462062469P 2014-10-10 2014-10-10
US201462067096P 2014-10-22 2014-10-22
US201462074842P 2014-11-04 2014-11-04
EP14193094 2014-11-13
PCT/EP2015/073486 WO2016055655A1 (en) 2014-10-10 2015-10-09 Inhalation device for use in aerosol therapy of respiratory diseases

Publications (1)

Publication Number Publication Date
TR201909589T4 true TR201909589T4 (tr) 2019-07-22

Family

ID=83280657

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/09589T TR201909589T4 (tr) 2014-10-10 2015-10-09 Solunum hastalıklarının aerosol terapisinde kullanıma yönelik inhalasyon cihazı.

Country Status (17)

Country Link
US (1) US10512739B2 (tr)
EP (1) EP3204095B8 (tr)
JP (1) JP6617151B2 (tr)
KR (1) KR102364212B1 (tr)
CN (1) CN106999420B (tr)
AU (1) AU2015329935B2 (tr)
CA (1) CA2963030C (tr)
DK (1) DK3204095T3 (tr)
ES (1) ES2732837T3 (tr)
HU (1) HUE044199T2 (tr)
PL (1) PL3204095T3 (tr)
PT (1) PT3204095T (tr)
RU (1) RU2700650C2 (tr)
SG (1) SG11201702699TA (tr)
SI (1) SI3204095T1 (tr)
TR (1) TR201909589T4 (tr)
WO (1) WO2016055655A1 (tr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180264219A1 (en) * 2015-08-28 2018-09-20 The Research Institute At Nationwide Children's Hospital Interactive spacer for respiratory device
WO2017191108A1 (en) 2016-05-02 2017-11-09 Ablynx Nv Treatment of rsv infection
US11285274B2 (en) 2016-05-03 2022-03-29 Pneuma Respiratory, Inc. Methods for the systemic delivery of therapeutic agents to the pulmonary system using a droplet delivery device
WO2017192773A1 (en) 2016-05-03 2017-11-09 Pneuma Respiratory, Inc. Methods for treatment of pulmonary lung diseases with improved therapeutic efficacy and improved dose efficiency
EP3452152A4 (en) * 2016-05-03 2020-01-01 Pneuma Respiratory, Inc. METHODS FOR GENERATING AND DELIVERING DROPLETS TO THE PULMONARY SYSTEM USING A DROPLET DELIVERY DEVICE
US11285285B2 (en) 2016-05-03 2022-03-29 Pneuma Respiratory, Inc. Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment
DK3519025T3 (da) * 2016-09-30 2023-01-30 De Motu Cordis Pty Ltd Indgivelsesanordning
WO2018099968A1 (en) * 2016-11-29 2018-06-07 Ablynx N.V. Treatment of infection by respiratory syncytial virus (rsv)
EP3634552A4 (en) 2017-05-19 2021-03-03 Pneuma Respiratory, Inc. DRY POWDER ADMINISTRATION DEVICE AND METHODS OF USE
CN111526914A (zh) 2017-10-04 2020-08-11 精呼吸股份有限公司 电子呼吸致动式直线型液滴输送装置及其使用方法
CA3079189A1 (en) 2017-10-17 2019-04-25 Pneuma Respiratory, Inc. Nasal drug delivery apparatus and methods of use
JP2021502178A (ja) 2017-11-08 2021-01-28 ニューマ・リスパイラトリー・インコーポレイテッド 小容積アンプルを有して呼吸により電気的に作動するインライン液滴送達装置および使用方法
US20200016360A1 (en) 2018-07-11 2020-01-16 Martin Allan Morris Low flow adaptor to deliver aerosols via nasal cannula without crashout
WO2020032814A1 (en) * 2018-08-09 2020-02-13 Armin Bidarian Moniri Device for speech therapy, administration of inhalation medication and for treatment of otitis, sinusitis and barotrauma
WO2020079055A1 (en) * 2018-10-19 2020-04-23 Vectura Delivery Devices Limited Pharmaceutical administration to neonates, infants and children
PL429292A1 (pl) * 2019-03-17 2020-09-21 Wiśniewski Jan Maska przeciwpyłowa
WO2020210735A1 (en) * 2019-04-12 2020-10-15 Sensory Cloud, Llc Thin-profile delivery apparatus and media cartridges
US20220387736A1 (en) * 2020-10-18 2022-12-08 Medshield, Llc Nebulizer system
TWI779663B (zh) * 2021-06-15 2022-10-01 岩成科技事業股份有限公司 震盪式吐氣正壓裝置
JP2024525200A (ja) 2021-06-22 2024-07-10 ニューマ・リスパイラトリー・インコーポレイテッド プッシュ排出を用いる液滴送達デバイス
CN113244491A (zh) * 2021-06-23 2021-08-13 南京力成药业有限公司 粉状药剂吸入器
CN113952320B (zh) * 2021-09-18 2022-03-18 健康元药业集团股份有限公司 一种包含妥布霉素吸入溶液的药物组件及其用途
KR102682100B1 (ko) * 2022-01-04 2024-07-05 주식회사 이엠텍 정량 분사 기능을 지닌 약액 에어로졸 흡입기
WO2024020041A1 (en) 2022-07-18 2024-01-25 Pneuma Respiratory, Inc. Small step size and high resolution aerosol generation system and method
US11850356B1 (en) * 2023-06-08 2023-12-26 Microneb Tech Holdings, Inc. Apparatus, methods, and systems for administering a medication to a patient from a capsule using an atomizer
US11944742B1 (en) * 2023-06-08 2024-04-02 Microneb Tech Holdings, Inc. Apparatus, methods, and systems for administering a medication to an animal
US11844900B1 (en) * 2023-06-08 2023-12-19 Microneb Tech Holdings, Inc. Apparatus, methods, and systems for administering a medication to a patient from a capsule using an atomizer
US11925748B1 (en) * 2023-06-08 2024-03-12 Microneb Tech Holdings, Inc. Apparatus, methods, and systems for administering a medication to a patient from a capsule using an atomizer

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430995A (en) * 1981-05-29 1984-02-14 Hilton Joseph R Power assisted air-purifying respirators
ES2052027T5 (es) 1988-11-11 2005-04-16 Medical Research Council Clonacion de secuencias de dominio variable de inmunoglobulina.
EP0656946B2 (en) 1992-08-21 2010-03-31 Vrije Universiteit Brussel Immunoglobulins devoid of light chains
NZ506453A (en) 1998-02-19 2003-02-28 Xcyte Therapies Inc Compositions and methods for regulating lymphocyte activation
SE9902627D0 (sv) * 1999-07-08 1999-07-08 Siemens Elema Ab Medical nebulizer
US20060073141A1 (en) 2001-06-28 2006-04-06 Domantis Limited Compositions and methods for treating inflammatory disorders
US7461263B2 (en) 2003-01-23 2008-12-02 Unspam, Llc. Method and apparatus for a non-revealing do-not-contact list system
JP2007521234A (ja) 2003-08-12 2007-08-02 ウィリアム エム ヤーブロー 尋常性ざ瘡の治療薬及び使用方法
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
CN100566770C (zh) 2004-04-02 2009-12-09 美国政府健康及人类服务部,疾病控制和预防中心 气雾化输送系统和方法
US7563443B2 (en) 2004-09-17 2009-07-21 Domantis Limited Monovalent anti-CD40L antibody polypeptides and compositions thereof
GB0521621D0 (en) 2005-10-24 2005-11-30 Domantis Ltd Tumor necrosis factor receptor 1 antagonists for treating respiratory diseases
MX2007006593A (es) 2004-12-02 2008-03-04 Domantis Ltd Anticuerpos de dominio simple anti-il 1r1 y sus usos terapeuticos.
EP1695728A1 (de) * 2005-02-23 2006-08-30 Activaero GmbH Bauteil für eine Inhalationsvorrichtung, Inhalationsvorrichtung mit diesem Bauteil und Steuerverfahren für ein solches Bauteil
DE102005010965B3 (de) * 2005-03-10 2006-08-03 Medspray Xmems Bv Inhalator mit einem Mischkanal zum Erzeugen eines zu inhalierenden Aerosols
US20110159003A1 (en) 2006-01-24 2011-06-30 Domantis Limited Ligands That Bind Il-4 and/or Il-13
DE102006006183A1 (de) * 2006-02-10 2007-08-16 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung für die Anwendung bei Frühgeborenen und Kleinkindern
US8225785B2 (en) * 2006-10-03 2012-07-24 Smiths Medical Asd, Inc. Vibratory PEP therapy system with medicated aerosol nebulizer
EP2121757A2 (en) 2007-02-21 2009-11-25 Ablynx N.V. Amino acid sequences directed against vascular endothelial growth factor and polypeptides comprising the same for the treatment of conditions and diseases characterized by excessive and/or pathological angiogenesis or neovascularization
WO2008116165A2 (en) 2007-03-21 2008-09-25 Next Safety, Inc. Methods and systems of delivering medication via inhalation
ES2663512T3 (es) 2007-05-24 2018-04-13 Ablynx N.V. Secuencias de aminoácidos dirigidas contra RANK-L y polipéptidos que comprenden las mismas para el tratamiento de enfermedades y trastornos óseos
WO2011163272A1 (en) * 2010-06-21 2011-12-29 Mannkind Corporation Dry powder drug delivery system and methods
DK2285439T3 (en) * 2008-04-04 2014-03-24 Nektar Therapeutics Aerosoliseringsanorning
US8464715B2 (en) * 2008-04-16 2013-06-18 Stephen Donald Flynn, SR. Multipurpose therapeutic face mask
DE102008022987A1 (de) * 2008-05-09 2009-11-12 Pari Pharma Gmbh Vernebler für Beatmungsmaschinen und Beatmungsmaschine mit einem solchen Vernebler
JP5713406B2 (ja) * 2008-12-02 2015-05-07 クール セラピューティクス, インコーポレイテッド 微細氷粒子を有する呼吸ガスの送達のためのシステム
EP2401013B1 (en) * 2009-02-27 2017-04-12 PARI GmbH Spezialisten für effektive Inhalation An aerosol inhalation device
CN105061592A (zh) 2009-06-05 2015-11-18 埃博灵克斯股份有限公司 用于预防和/或治疗呼吸道感染的单价、二价和三价抗人呼吸道合胞病毒(hrsv)纳米抗体构建体
EP2521583B1 (en) * 2010-01-07 2020-10-28 Koninklijke Philips N.V. A feedback and compliance device for an inhaler
WO2011098552A2 (en) 2010-02-11 2011-08-18 Ablynx Nv Methods and compositions for the preparation of aerosols
WO2011125061A2 (en) * 2010-04-07 2011-10-13 Kast Silicone Ltd. Means and method for administering medicaments to infants
EP2720743B1 (en) * 2011-06-17 2021-11-24 Nostrum Technologies, LLC Mask for administering an inhalable medication
WO2013067164A1 (en) 2011-11-04 2013-05-10 Discovery Laboratories, Inc. Ventilation circuit adaptor and proximal aerosol delivery system
CN104010685B (zh) 2011-12-27 2017-03-22 维克多瑞有限责任公司 带有反馈系统的吸入装置
PL2846859T3 (pl) * 2012-03-09 2017-07-31 Vectura Gmbh Kanał mieszania do urządzenia do inhalacji i urządzenie do inhalacji
DK2724741T3 (en) * 2012-10-26 2017-09-18 Vectura Gmbh Inhalation device for use in aerosol treatment
TWI659968B (zh) 2013-03-14 2019-05-21 再生元醫藥公司 針對呼吸道融合病毒f蛋白質的人類抗體及其使用方法
CN107206069A (zh) * 2014-10-10 2017-09-26 埃博灵克斯股份有限公司 Rsv感染的治疗
WO2017191108A1 (en) * 2016-05-02 2017-11-09 Ablynx Nv Treatment of rsv infection
EP3452152A4 (en) * 2016-05-03 2020-01-01 Pneuma Respiratory, Inc. METHODS FOR GENERATING AND DELIVERING DROPLETS TO THE PULMONARY SYSTEM USING A DROPLET DELIVERY DEVICE

Also Published As

Publication number Publication date
RU2017115845A3 (tr) 2019-04-12
CA2963030C (en) 2021-07-13
PT3204095T (pt) 2019-07-11
WO2016055655A1 (en) 2016-04-14
EP3204095A1 (en) 2017-08-16
AU2015329935A1 (en) 2017-04-20
US20170304565A1 (en) 2017-10-26
JP2017534419A (ja) 2017-11-24
CN106999420B (zh) 2021-08-10
NZ730120A (en) 2020-10-30
HUE044199T2 (hu) 2019-10-28
KR20170091087A (ko) 2017-08-08
CN106999420A (zh) 2017-08-01
KR102364212B1 (ko) 2022-02-17
DK3204095T3 (da) 2019-07-15
ES2732837T3 (es) 2019-11-26
AU2015329935B2 (en) 2019-09-19
EP3204095B1 (en) 2019-05-29
JP6617151B2 (ja) 2019-12-11
US10512739B2 (en) 2019-12-24
PL3204095T3 (pl) 2019-10-31
RU2700650C2 (ru) 2019-09-18
EP3204095B8 (en) 2019-07-10
SI3204095T1 (sl) 2019-08-30
CA2963030A1 (en) 2016-04-14
RU2017115845A (ru) 2018-11-13
SG11201702699TA (en) 2017-04-27

Similar Documents

Publication Publication Date Title
TR201909589T4 (tr) Solunum hastalıklarının aerosol terapisinde kullanıma yönelik inhalasyon cihazı.
NZ732004A (en) Patient interface for respiratory therapy
MX2023000920A (es) Dispositivo combinado de entrenamiento de musculo respiratorio y presion expiratoria positiva oscilante.
CL2016002387A1 (es) Dispositivo y sistema de adiestramiento para inhalación, para la práctica de un procedimiento de inhalación por parte de un paciente
NZ716698A (en) Patient interface
PH12017500260A1 (en) Ventilation mask
MX2020005926A (es) Interfaz del paciente y método para hacer la misma.
SG10201807070YA (en) Respiratory mask with nasogastric tube path
MX2017004796A (es) Sistemas y metodos para la sintesis de oxido nitrico.
MX2016014142A (es) Respirador de cara para filtracion con ubicacion optimizada de filtro facial.
MX2019004034A (es) Metodos para administrar altas concentraciones de oxido nitrico.
PH12015501202A1 (en) Inhalation device, control method and computer program
PT3511044T (pt) Sistema para dispensar óxido nítrico a doentes que dele têm necessidade, recebendo gás respiratório de um ventilador que varia pelo menos a pressão e / ou o fluxo usando medição de fluxo de gás terapêutico (no) melhorada
EA201492044A1 (ru) Ингалятор, содержащий внутренний корпус, имеющий канал для воздуха
NZ630609A (en) Discreet respiratory therapy system
GB2546949A (en) Substance delivery arrangement for gas therapy device
MX361847B (es) Nebulizador para bebés y pacientes con compromiso respiratorio.
MX2016001500A (es) Máscara para prevención de apnea del sueño.
PH12016500760A1 (en) Protective breathing mask with the collective inhalation and exhalation hole
TR201109804A2 (tr) Tek dozlu inhalasyon cihazı.
MX374842B (es) Inhalador de polvo seco.
AU2018264061B2 (en) Inhaler
MX2018012581A (es) Dispositivo espaciador para un inhalador.
BR112015011246A2 (pt) aparelho para entregar nasalmente uma ventilação com jato supraglótica método e sistema para ventilação e/ou oxigenação de um indivíduo com respiração comprometida; e método para a sincronização de respiração de um indivíduo com um ventilador de jato
MX2023004028A (es) Dispositivo y metodo para la dispersion de no de concentracion alta con gas de terapia de inhalacion.