TR199901663T2 - Burundan tatbikat için sulu süspansiyon - Google Patents

Burundan tatbikat için sulu süspansiyon

Info

Publication number
TR199901663T2
TR199901663T2 TR1999/01663T TR9901663T TR199901663T2 TR 199901663 T2 TR199901663 T2 TR 199901663T2 TR 1999/01663 T TR1999/01663 T TR 1999/01663T TR 9901663 T TR9901663 T TR 9901663T TR 199901663 T2 TR199901663 T2 TR 199901663T2
Authority
TR
Turkey
Prior art keywords
aqueous suspension
suspension
developed
nasal administration
mycrystalline
Prior art date
Application number
TR1999/01663T
Other languages
English (en)
Inventor
Doi Koji
Original Assignee
Nicholas Bodor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicholas Bodor filed Critical Nicholas Bodor
Publication of TR199901663T2 publication Critical patent/TR199901663T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

Mükemmel iltihaplanmaya ve alerjiye karsi etkinlige sahip olan lateprednol etabonatin distan uygulanmak için bir ilaç seklinde gelistirilmesi beklenmekle birlikte, bir sulu süspansiyon halinde formüle edildiginde, parçaciklarin birikme ve çökelme egilimi ortaya çikmaktadir. Bu bulusa göre, süspansiyonun uzun vadede stabilizasyonu, loteprednol etabonatin miktokristalin selüloz karmeloz sodyum ile formüle edilmesiyle basarili biçimde elde edilmistir. Üstelik, sonuçtaki süspansiyon, mükemmel ölçüde gelismis bir burun içinde tutulma arzetmekte ve hiç bir dermal ya da mukozal tahrisata neden olmamaktadir.
TR1999/01663T 1997-01-16 1998-01-14 Burundan tatbikat için sulu süspansiyon TR199901663T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1966497 1997-01-16

Publications (1)

Publication Number Publication Date
TR199901663T2 true TR199901663T2 (tr) 1999-09-21

Family

ID=12005518

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/01663T TR199901663T2 (tr) 1997-01-16 1998-01-14 Burundan tatbikat için sulu süspansiyon

Country Status (33)

Country Link
US (1) US6368616B1 (tr)
EP (1) EP0973501B1 (tr)
KR (1) KR100471708B1 (tr)
CN (1) CN1126535C (tr)
AR (1) AR011773A1 (tr)
AT (1) ATE249205T1 (tr)
AU (1) AU730953C (tr)
BR (1) BR9806771A (tr)
CA (1) CA2278025C (tr)
CZ (1) CZ294919B6 (tr)
DE (1) DE69818026T2 (tr)
DK (1) DK0973501T3 (tr)
EA (1) EA001775B1 (tr)
ES (1) ES2206880T3 (tr)
HK (1) HK1026138A1 (tr)
HU (1) HU226613B1 (tr)
ID (1) ID21892A (tr)
IL (1) IL130979A0 (tr)
LT (1) LT4677B (tr)
LV (1) LV12449B (tr)
MX (1) MXPA99006628A (tr)
NO (1) NO324619B1 (tr)
NZ (2) NZ336990A (tr)
PL (1) PL190753B1 (tr)
PT (1) PT973501E (tr)
RS (1) RS49701B (tr)
SI (1) SI20057A (tr)
SK (1) SK283164B6 (tr)
TR (1) TR199901663T2 (tr)
TW (1) TW503113B (tr)
UA (1) UA52722C2 (tr)
WO (1) WO1998031343A2 (tr)
ZA (1) ZA98303B (tr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI243687B (en) 1998-04-21 2005-11-21 Teijin Ltd Pharmaceutical composition for application to mucosa
EP1025859B1 (en) 1998-08-26 2006-06-28 Teijin Limited Powdery pernasal compositions
DE19947235A1 (de) * 1999-09-30 2001-04-05 Asta Medica Ag Neue Kombination von Loteprednol und beta¶2¶-Adrenorezeptor-Agonisten
AR026073A1 (es) 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
US6565832B1 (en) * 2000-01-31 2003-05-20 Schering-Plough Healthcare Products, Inc. Spray composition with reduced dripping
KR100988542B1 (ko) * 2001-06-18 2010-10-20 노벤 파머수티컬즈, 인코퍼레이티드 경피 시스템에서의 강화된 약물 전달
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US7811606B2 (en) * 2003-04-16 2010-10-12 Dey, L.P. Nasal pharmaceutical formulations and methods of using the same
US9808471B2 (en) * 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
US8912174B2 (en) 2003-04-16 2014-12-16 Mylan Pharmaceuticals Inc. Formulations and methods for treating rhinosinusitis
EP1658083B1 (en) * 2003-06-19 2007-08-08 BODOR, Nicholas S. Enhancement of activity and/or duration of action of selected anti-inflammatory steroids
MXPA05013898A (es) * 2003-06-19 2006-05-25 Nicholas S Bodor Mejoramiento de la actividad y/o duracion de la accion de esteroides antiinflamatorios suaves para la aplicacion topica u otra aplicacion local.
US20050095205A1 (en) * 2003-10-31 2005-05-05 Ramesh Krishnamoorthy Combination of loteprednol etabonate and tobramycin for topical ophthalmic use
ATE441419T1 (de) 2004-03-25 2009-09-15 Bausch & Lomb Verwendung von loteprednoletabonat zur behanldung von trockenen augen
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
US20070110812A1 (en) * 2005-11-14 2007-05-17 Bausch & Lomb Incorporated Ophthalmic composition for dry eye therapy
US7687484B2 (en) * 2006-05-25 2010-03-30 Bodor Nicholas S Transporter enhanced corticosteroid activity
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
WO2012119261A1 (en) * 2011-03-10 2012-09-13 Biocia Inc. Enhanced artificial mucus composition comprising hyaluronan for the treatment of rhinitis
CA2851492A1 (en) 2011-09-22 2013-03-28 Bausch & Lomb Incorporated Ophthalmic gel compositions
TWI783890B (zh) 2017-08-24 2022-11-11 丹麥商諾佛 儂迪克股份有限公司 Glp-1組成物及其用途
CA3165359A1 (en) 2020-02-18 2021-07-22 Dorthe Kot Engelund Glp-1 compositions and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5540930A (en) 1993-10-25 1996-07-30 Pharmos Corporation Suspension of loteprednol etabonate for ear, eye, or nose treatment
EP0709099A3 (en) 1994-09-28 1996-07-24 Senju Pharma Co Aqueous suspension for nasal administration containing cyclodextrin
KR100508227B1 (ko) 1997-03-14 2006-03-23 센주 세이야꾸 가부시키가이샤 로테프레드놀에타보네이트수성현탁액

Also Published As

Publication number Publication date
TW503113B (en) 2002-09-21
HU226613B1 (en) 2009-04-28
WO1998031343A3 (en) 1998-09-17
WO1998031343A2 (en) 1998-07-23
DE69818026T2 (de) 2004-07-08
SK283164B6 (sk) 2003-03-04
BR9806771A (pt) 2000-05-16
CZ294919B6 (cs) 2005-04-13
NO993453L (no) 1999-07-13
AR011773A1 (es) 2000-09-13
EP0973501B1 (en) 2003-09-10
HUP0002473A3 (en) 2001-01-29
EA001775B1 (ru) 2001-08-27
ATE249205T1 (de) 2003-09-15
AU730953B2 (en) 2001-03-22
KR100471708B1 (ko) 2005-03-07
SI20057A (sl) 2000-04-30
DK0973501T3 (da) 2004-01-19
DE69818026D1 (de) 2003-10-16
MXPA99006628A (es) 2005-01-10
ID21892A (id) 1999-08-05
AU5495298A (en) 1998-08-07
US6368616B1 (en) 2002-04-09
AU730953C (en) 2002-02-07
NO324619B1 (no) 2007-11-26
PL334614A1 (en) 2000-03-13
NZ509908A (en) 2004-12-24
EP0973501A2 (en) 2000-01-26
RS49701B (sr) 2007-12-31
LT99100A (en) 2000-02-25
CN1126535C (zh) 2003-11-05
CA2278025C (en) 2005-09-06
PL190753B1 (pl) 2006-01-31
UA52722C2 (uk) 2003-01-15
ES2206880T3 (es) 2004-05-16
CZ237499A3 (cs) 2000-01-12
ZA98303B (en) 1998-07-20
SK94899A3 (en) 2000-05-16
PT973501E (pt) 2004-02-27
KR20000070214A (ko) 2000-11-25
CA2278025A1 (en) 1998-07-23
CN1250370A (zh) 2000-04-12
HK1026138A1 (en) 2000-12-08
NZ336990A (en) 2001-03-30
LV12449A (lv) 2000-04-20
HUP0002473A2 (hu) 2000-12-28
YU36199A (sh) 2002-09-19
EA199900659A1 (ru) 2000-02-28
IL130979A0 (en) 2001-01-28
LT4677B (lt) 2000-07-25
NO993453D0 (no) 1999-07-13
LV12449B (en) 2000-09-20

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