SU1517313A1 - Derivatives of 2-(fluorenylidene-9-hydrazono)-thiazolidone-4 showing antiviral effect with relation to coxsackie b4 virus and vesicular stomatitis virus
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Derivatives of 2-(fluorenylidene-9-hydrazono)-thiazolidone-4 showing antiviral effect with relation to coxsackie b4 virus and vesicular stomatitis virus
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
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Abstract
FIELD: organic chemistry. SUBSTANCE: synthesis is carried out from fluorenone-9 and p-dimethylbenzaldehyde or furfural in the medium of ethanol in the presence of monochloroacetic acid and sodium carbonate (anhydrous) at boiling. Yield, % , m. p. C, empirical formula: a) 15.2; 102-104; CHNOS·HCl HCl, b) 51.4; 147-150; CHNOS.. New compounds show low toxicity (MPD = 62.5 and 15 mcg/ml, LD= 980 and 2000 mg/kg) and chemiotherapeutic index with relation to stomatitis 15.5 and 3.75. EFFECT: synthesis of compounds with activity without specifity for substances of this class. 3 tbl
SU4359584/04A1988-01-071988-01-07Derivatives of 2-(fluorenylidene-9-hydrazono)-thiazolidone-4 showing antiviral effect with relation to coxsackie b4 virus and vesicular stomatitis virus
SU1517313A1
(en)
Derivatives of 2-(fluorenylidene-9-hydrazono)-thiazolidone-4 showing antiviral effect with relation to coxsackie b4 virus and vesicular stomatitis virus
Derivatives of 2-(fluorenylidene-9-hydrazono)-thiazolidone-4 showing antiviral effect with relation to coxsackie b4 virus and vesicular stomatitis virus
Derivatives of 2-(fluorenylidene-9-hydrazono)-thiazolidone-4 showing antiviral effect with relation to coxsackie b4 virus and vesicular stomatitis virus
NEW IMIDAZOKINOXALINES AND SALTS THEREOF, SET FOR PREPARATION AND USE THEREOF AS A MEDICINAL PRODUCT AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
Derivatives of 2-(fluorenylidene-9-hydrazono)-thiazolidone-4 showing antiviral effect with relation to coxsackie b4 virus and vesicular stomatitis virus