SK55997A3 - Small particle formation - Google Patents

Small particle formation Download PDF

Info

Publication number
SK55997A3
SK55997A3 SK559-97A SK55997A SK55997A3 SK 55997 A3 SK55997 A3 SK 55997A3 SK 55997 A SK55997 A SK 55997A SK 55997 A3 SK55997 A3 SK 55997A3
Authority
SK
Slovakia
Prior art keywords
polymer
solvent
organic mixture
mixture
solution
Prior art date
Application number
SK559-97A
Other languages
English (en)
Slovak (sk)
Inventor
Sylvan Frank
Jan-Erik Lofroth
Levon Bostanian
Original Assignee
Univ Ohio State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ohio State Res Found filed Critical Univ Ohio State Res Found
Publication of SK55997A3 publication Critical patent/SK55997A3/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/10—Complex coacervation, i.e. interaction of oppositely charged particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Confectionery (AREA)
  • Soft Magnetic Materials (AREA)
  • Surgical Instruments (AREA)
  • Steroid Compounds (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
SK559-97A 1994-11-09 1995-11-03 Small particle formation SK55997A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9403846A SE9403846D0 (sv) 1994-11-09 1994-11-09 Small particle formation
PCT/SE1995/001302 WO1996014833A1 (en) 1994-11-09 1995-11-03 Small particle formation

Publications (1)

Publication Number Publication Date
SK55997A3 true SK55997A3 (en) 1998-01-14

Family

ID=20395907

Family Applications (1)

Application Number Title Priority Date Filing Date
SK559-97A SK55997A3 (en) 1994-11-09 1995-11-03 Small particle formation

Country Status (27)

Country Link
US (1) US5780062A (hu)
EP (1) EP0788350B1 (hu)
JP (1) JP4098827B2 (hu)
KR (1) KR970706799A (hu)
CN (1) CN1165478A (hu)
AT (1) ATE213625T1 (hu)
AU (1) AU700644B2 (hu)
BR (1) BR9509720A (hu)
CA (1) CA2203512A1 (hu)
CZ (1) CZ129597A3 (hu)
DE (1) DE69525639T2 (hu)
DK (1) DK0788350T3 (hu)
EE (1) EE9700214A (hu)
ES (1) ES2173204T3 (hu)
FI (1) FI118511B (hu)
HU (1) HUT77629A (hu)
IL (1) IL115878A0 (hu)
IS (1) IS4467A (hu)
NO (1) NO971986D0 (hu)
NZ (1) NZ295497A (hu)
PL (1) PL320425A1 (hu)
PT (1) PT788350E (hu)
SE (1) SE9403846D0 (hu)
SK (1) SK55997A3 (hu)
TR (1) TR199501400A2 (hu)
WO (1) WO1996014833A1 (hu)
ZA (1) ZA959386B (hu)

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US6951656B2 (en) * 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
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US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
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CN100512798C (zh) * 2000-12-22 2009-07-15 巴克斯特国际公司 亚微米颗粒悬浮液制备方法
US6977085B2 (en) * 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
US7193084B2 (en) * 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
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US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
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US7511079B2 (en) * 2003-03-24 2009-03-31 Baxter International Inc. Methods and apparatuses for the comminution and stabilization of small particles
MXPA05012467A (es) * 2003-05-19 2006-02-22 Baxter Int Particulas solidas que comprenden un anticonvulsivo o un inmunosupresor revestido con uno o mas modificadores de superficie.
WO2004111033A1 (en) * 2003-06-18 2004-12-23 Astrazeneca Ab 2-substitued 5, 6-diaryl-pyrazine derivatives as cb1 modulator.
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GB0314261D0 (en) * 2003-06-19 2003-07-23 Astrazeneca Ab Therapeutic agents
US8986736B2 (en) * 2003-06-24 2015-03-24 Baxter International Inc. Method for delivering particulate drugs to tissues
BRPI0414970A2 (pt) * 2003-06-24 2012-12-11 Baxter Int método para transporte de drogas ao cérebro
PT1663321E (pt) 2003-09-22 2012-11-15 Baxter Int Esterilização a alta pressão para esterilizar definitivamente preparações farmacêuticas e produtos médicos
JP2007507527A (ja) * 2003-09-30 2007-03-29 スフェリックス， インコーポレイテッド 生物学的に活性なナノ粒子治療用因子
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Also Published As

Publication number Publication date
FI971947A0 (fi) 1997-05-07
KR970706799A (ko) 1997-12-01
DE69525639D1 (de) 2002-04-04
CZ129597A3 (en) 1997-12-17
HUT77629A (hu) 1998-06-29
ES2173204T3 (es) 2002-10-16
AU700644B2 (en) 1999-01-14
ZA959386B (en) 1996-05-09
EP0788350A1 (en) 1997-08-13
FI971947A (fi) 1997-05-07
JP4098827B2 (ja) 2008-06-11
EE9700214A (et) 1998-04-15
AU3885195A (en) 1996-06-06
CN1165478A (zh) 1997-11-19
JPH10508840A (ja) 1998-09-02
DE69525639T2 (de) 2002-08-29
NO971986L (no) 1997-04-29
US5780062A (en) 1998-07-14
NO971986D0 (no) 1997-04-29
CA2203512A1 (en) 1996-05-23
IL115878A0 (en) 1996-01-31
PT788350E (pt) 2002-07-31
DK0788350T3 (da) 2002-04-29
ATE213625T1 (de) 2002-03-15
FI118511B (fi) 2007-12-14
TR199501400A2 (tr) 1996-06-21
BR9509720A (pt) 1997-10-21
IS4467A (is) 1997-04-21
WO1996014833A1 (en) 1996-05-23
EP0788350B1 (en) 2002-02-27
NZ295497A (en) 1998-05-27
PL320425A1 (en) 1997-09-29
SE9403846D0 (sv) 1994-11-09

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