SK286950B6 - Farmaceutický prostriedok, ktorý obsahuje jednu alebo viacero solí tiotrópia v kombinácii s jednou alebo viacerými soľami salmeterolu, vo forme inhalačného prášku a jeho použitie - Google Patents
Farmaceutický prostriedok, ktorý obsahuje jednu alebo viacero solí tiotrópia v kombinácii s jednou alebo viacerými soľami salmeterolu, vo forme inhalačného prášku a jeho použitie Download PDFInfo
- Publication number
- SK286950B6 SK286950B6 SK50015-2009A SK500152009A SK286950B6 SK 286950 B6 SK286950 B6 SK 286950B6 SK 500152009 A SK500152009 A SK 500152009A SK 286950 B6 SK286950 B6 SK 286950B6
- Authority
- SK
- Slovakia
- Prior art keywords
- compound
- acid
- salts
- pharmaceutical composition
- salmeterol
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10056104A DE10056104A1 (de) | 2000-11-13 | 2000-11-13 | Neue Arzneimittelkompositionen auf der Basis von Tiotropiumsalzen und Salzen des Salmeterols |
| PCT/EP2001/012962 WO2002038154A1 (de) | 2000-11-13 | 2001-11-09 | Neue arzneimittelkompositionen auf der basis von tiotropiumsalzen und salzen des salmeterols |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK286950B6 true SK286950B6 (sk) | 2009-08-06 |
Family
ID=7663071
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK50015-2009A SK286950B6 (sk) | 2000-11-13 | 2001-11-09 | Farmaceutický prostriedok, ktorý obsahuje jednu alebo viacero solí tiotrópia v kombinácii s jednou alebo viacerými soľami salmeterolu, vo forme inhalačného prášku a jeho použitie |
| SK741-2003A SK286939B6 (sk) | 2000-11-13 | 2001-11-09 | Inhalačný roztok bez hnacieho plynu, ktorý obsahuje jednu alebo viacero solí tiotrópia v kombinácii s jednou alebo viacerými soľami salmeterolu, a jeho použitie |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK741-2003A SK286939B6 (sk) | 2000-11-13 | 2001-11-09 | Inhalačný roztok bez hnacieho plynu, ktorý obsahuje jednu alebo viacero solí tiotrópia v kombinácii s jednou alebo viacerými soľami salmeterolu, a jeho použitie |
Country Status (32)
| Country | Link |
|---|---|
| EP (3) | EP1514546B1 (cs) |
| JP (2) | JP4282322B2 (cs) |
| KR (2) | KR100940752B1 (cs) |
| CN (1) | CN1678318A (cs) |
| AT (2) | ATE362761T1 (cs) |
| AU (3) | AU2002227910B2 (cs) |
| BG (1) | BG107781A (cs) |
| BR (1) | BR0115226A (cs) |
| CA (1) | CA2429012A1 (cs) |
| CY (1) | CY1106774T1 (cs) |
| CZ (1) | CZ20031444A3 (cs) |
| DE (3) | DE10056104A1 (cs) |
| DK (2) | DK1514546T3 (cs) |
| EA (1) | EA007904B1 (cs) |
| EC (1) | ECSP034571A (cs) |
| EE (1) | EE200300228A (cs) |
| ES (2) | ES2287629T3 (cs) |
| HR (1) | HRP20030378A2 (cs) |
| HU (1) | HUP0301447A3 (cs) |
| IL (2) | IL155718A0 (cs) |
| MX (1) | MXPA03004164A (cs) |
| NO (1) | NO20032111L (cs) |
| NZ (1) | NZ526400A (cs) |
| PL (1) | PL205330B1 (cs) |
| PT (2) | PT1335728E (cs) |
| RS (2) | RS20090105A (cs) |
| SG (1) | SG167657A1 (cs) |
| SI (2) | SI1514546T1 (cs) |
| SK (2) | SK286950B6 (cs) |
| UA (1) | UA74853C2 (cs) |
| WO (1) | WO2002038154A1 (cs) |
| ZA (1) | ZA200302921B (cs) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| US7214687B2 (en) | 1999-07-14 | 2007-05-08 | Almirall Ag | Quinuclidine derivatives and medicinal compositions containing the same |
| JP2003514841A (ja) * | 1999-11-23 | 2003-04-22 | グラクソ グループ リミテッド | サルメテロールの医薬製剤 |
| CA2459493C (en) * | 2001-09-14 | 2011-08-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New pharmaceutical compositions for inhalation |
| DE10214263A1 (de) * | 2002-03-28 | 2003-10-16 | Boehringer Ingelheim Pharma | HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum |
| US7311894B2 (en) | 2002-03-28 | 2007-12-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | HFA suspension formulations containing an anticholinergic |
| US7244415B2 (en) | 2002-03-28 | 2007-07-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | HFA suspension formulations of an anhydrate |
| DE10256080A1 (de) * | 2002-11-29 | 2004-06-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropiumhaltige Arzneimittelkombination für die Inhalation |
| US7250426B2 (en) | 2002-11-29 | 2007-07-31 | Boehringer Ingelheim Pharma Gmbh & Co Kg | Tiotropium-containing pharmaceutical combination for inhalation |
| BR0317340A (pt) * | 2002-12-16 | 2005-11-08 | Boehringer Ingelheim Pharma | Formulações de hfc em solução contendo tiotrópio |
| UA83813C2 (ru) * | 2002-12-20 | 2008-08-26 | Бёрингер Ингельхайм Фарма Гмбх & Ко. Кг | Порошковое лекарственное средство, которое содержит соль тиотропия и ксинафоат салметерола |
| DE10345065A1 (de) * | 2003-09-26 | 2005-04-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum |
| KR20060102561A (ko) * | 2003-11-03 | 2006-09-27 | 베링거 인겔하임 인터내셔날 게엠베하 | 신규한 티오트로피움염, 이의 제조 방법 및 이를 함유하는약제학적 제형 |
| ATE460414T1 (de) * | 2003-11-03 | 2010-03-15 | Boehringer Ingelheim Int | Verfahren zur herstellung von tiotropiumsalzen |
| PL1905451T3 (pl) * | 2004-05-31 | 2010-05-31 | Almirall Sa | Kombinacje obejmujące środki przeciwmuskarynowe i kortykosteroidy |
| ES2257152B1 (es) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
| PT1881980E (pt) | 2005-05-02 | 2012-12-06 | Boehringer Ingelheim Int | Novas formas cristalinas de brometo de tiotrópio |
| EP1959942A1 (en) * | 2005-08-06 | 2008-08-27 | Boehringer Ingelheim International GmbH | Method for the treatment of dyspnea comprising combined administration of tiotropium salts and salts of salmeterol |
| ES2298049B1 (es) | 2006-07-21 | 2009-10-20 | Laboratorios Almirall S.A. | Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano. |
| EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| US20120220557A1 (en) * | 2011-02-17 | 2012-08-30 | Chiesi Farmaceutici S.P.A. | Liquid propellant-free formulation comprising an antimuscarinic drug |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
| WO2013127738A1 (de) * | 2012-02-28 | 2013-09-06 | Boehringer Ingelheim International Gmbh | Neue treibgashaltige tiotropium-formulierung |
| WO2015065222A1 (ru) * | 2013-10-28 | 2015-05-07 | Шолекс Девелопмент Гмбх | Фармацевтический ингаляционный препарат для лечения бронхиальной астмы и хронической обструктивной болезни легких, содержащий в качестве активного вещества микронизированный тиотропия бромид, и способ его получения |
| TW201835041A (zh) | 2017-02-17 | 2018-10-01 | 印度商托仁特生技有限公司 | 具β-腎上腺素促效劑及抗蕈毒活性化合物 |
| WO2019142214A1 (en) * | 2018-01-19 | 2019-07-25 | Cipla Limited | Pharmaceutical composition comprising tiotropium for inhalation |
| CN111971034A (zh) * | 2018-07-26 | 2020-11-20 | 四川海思科制药有限公司 | 一种含格隆铵盐的气雾剂药物组合物及其制备方法与应用 |
| WO2020019952A1 (zh) * | 2018-07-26 | 2020-01-30 | 四川海思科制药有限公司 | 一种含格隆铵盐及茚达特罗盐的气雾剂药物组合物及其制备方法与应用 |
| US11642372B2 (en) | 2020-05-01 | 2023-05-09 | Tygrus, LLC | Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses |
| US12042514B2 (en) | 2020-05-01 | 2024-07-23 | Tygrus, LLC | Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses |
| US11826382B2 (en) | 2020-05-01 | 2023-11-28 | Tygrus, LLC | Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses |
| WO2022119661A1 (en) * | 2020-12-04 | 2022-06-09 | Tygrus, LLC | THERAPEUTIC MATERIAL WITH LOW pH AND LOW TOXICITY ACTIVE AGAINST AT LEAST ONE PATHOGEN FOR ADDRESSING PATIENTS WITH RESPIRATORY ILLNESSES |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4570251B2 (ja) * | 1998-07-24 | 2010-10-27 | ヤゴテック アーゲー | 医薬用エーロゾル製剤 |
| DE19835346A1 (de) * | 1998-08-05 | 2000-02-10 | Boehringer Ingelheim Pharma | Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren |
| DE19847970A1 (de) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Lagerfähige Wirkstoff-Formulierung |
| DE19847971A1 (de) * | 1998-10-17 | 1999-09-02 | Schiering | Verfahren und Einrichtung zur Verhinderung von Filterbränden (Staubfilter) |
| DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
| DE19961300A1 (de) * | 1999-12-18 | 2001-06-21 | Asta Medica Ag | Vorratssystem für Arzneimittel in Pulverform und damit ausgestatteter Inhalator |
-
2000
- 2000-11-13 DE DE10056104A patent/DE10056104A1/de not_active Withdrawn
-
2001
- 2001-09-11 UA UA2003065486A patent/UA74853C2/uk unknown
- 2001-11-09 RS RSP-2009/0105A patent/RS20090105A/sr unknown
- 2001-11-09 AU AU2002227910A patent/AU2002227910B2/en not_active Ceased
- 2001-11-09 AT AT04028508T patent/ATE362761T1/de active
- 2001-11-09 ES ES04028508T patent/ES2287629T3/es not_active Expired - Lifetime
- 2001-11-09 SI SI200130751T patent/SI1514546T1/sl unknown
- 2001-11-09 WO PCT/EP2001/012962 patent/WO2002038154A1/de not_active Ceased
- 2001-11-09 EA EA200300503A patent/EA007904B1/ru not_active IP Right Cessation
- 2001-11-09 NZ NZ526400A patent/NZ526400A/en unknown
- 2001-11-09 SK SK50015-2009A patent/SK286950B6/sk not_active IP Right Cessation
- 2001-11-09 IL IL15571801A patent/IL155718A0/xx unknown
- 2001-11-09 KR KR1020087020177A patent/KR100940752B1/ko not_active Expired - Fee Related
- 2001-11-09 DE DE50105729T patent/DE50105729D1/de not_active Expired - Lifetime
- 2001-11-09 PL PL365989A patent/PL205330B1/pl not_active IP Right Cessation
- 2001-11-09 EP EP04028508A patent/EP1514546B1/de not_active Expired - Lifetime
- 2001-11-09 AU AU2791002A patent/AU2791002A/xx active Pending
- 2001-11-09 EP EP01989446A patent/EP1335728B1/de not_active Expired - Lifetime
- 2001-11-09 EP EP07104722A patent/EP1808174A1/de not_active Withdrawn
- 2001-11-09 CA CA002429012A patent/CA2429012A1/en not_active Abandoned
- 2001-11-09 CZ CZ20031444A patent/CZ20031444A3/cs unknown
- 2001-11-09 SK SK741-2003A patent/SK286939B6/sk not_active IP Right Cessation
- 2001-11-09 JP JP2002540737A patent/JP4282322B2/ja not_active Expired - Lifetime
- 2001-11-09 KR KR1020037006434A patent/KR100886094B1/ko not_active Expired - Fee Related
- 2001-11-09 RS YUP-355/03A patent/RS50286B/sr unknown
- 2001-11-09 AT AT01989446T patent/ATE291428T1/de active
- 2001-11-09 DK DK04028508T patent/DK1514546T3/da active
- 2001-11-09 ES ES01989446T patent/ES2240549T3/es not_active Expired - Lifetime
- 2001-11-09 EE EEP200300228A patent/EE200300228A/xx unknown
- 2001-11-09 PT PT01989446T patent/PT1335728E/pt unknown
- 2001-11-09 DK DK01989446T patent/DK1335728T3/da active
- 2001-11-09 SI SI200130347T patent/SI1335728T1/xx unknown
- 2001-11-09 MX MXPA03004164A patent/MXPA03004164A/es active IP Right Grant
- 2001-11-09 HU HU0301447A patent/HUP0301447A3/hu unknown
- 2001-11-09 SG SG200505149-5A patent/SG167657A1/en unknown
- 2001-11-09 DE DE50112535T patent/DE50112535D1/de not_active Expired - Lifetime
- 2001-11-09 BR BR0115226-2A patent/BR0115226A/pt not_active Application Discontinuation
- 2001-11-09 PT PT04028508T patent/PT1514546E/pt unknown
- 2001-11-09 HR HR20030378A patent/HRP20030378A2/hr not_active Application Discontinuation
- 2001-11-09 CN CNA018187773A patent/CN1678318A/zh active Pending
-
2003
- 2003-04-14 ZA ZA200302921A patent/ZA200302921B/en unknown
- 2003-04-28 EC EC2003004571A patent/ECSP034571A/es unknown
- 2003-05-01 IL IL155718A patent/IL155718A/en not_active IP Right Cessation
- 2003-05-08 BG BG107781A patent/BG107781A/bg unknown
- 2003-05-12 NO NO20032111A patent/NO20032111L/no not_active Application Discontinuation
-
2004
- 2004-12-08 JP JP2004355226A patent/JP4282594B2/ja not_active Expired - Lifetime
-
2007
- 2007-05-22 AU AU2007202303A patent/AU2007202303B2/en not_active Ceased
- 2007-07-30 CY CY20071101011T patent/CY1106774T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20101109 |