SK285353B6 - Substituované benzénsulfónamidy ako proliečivá COX-2 inhibítorov, farmaceutická kompozícia a spôsobich prípravy a použitia - Google Patents

Substituované benzénsulfónamidy ako proliečivá COX-2 inhibítorov, farmaceutická kompozícia a spôsobich prípravy a použitia Download PDF

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Publication number
SK285353B6
SK285353B6 SK1242-98A SK124298A SK285353B6 SK 285353 B6 SK285353 B6 SK 285353B6 SK 124298 A SK124298 A SK 124298A SK 285353 B6 SK285353 B6 SK 285353B6
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SK
Slovakia
Prior art keywords
phenyl
sulfonyl
methyl
phenylisoxazol
acetamide
Prior art date
Application number
SK1242-98A
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English (en)
Slovak (sk)
Other versions
SK124298A3 (en
Inventor
John J. Talley
James W. Malecha
Stephen Bertenshaw
Matthew J. Graneto
Jeffery S. Carter
Jinglin Li
Srinivasan Nagarajan
David L. Brown
Donald J. Rogier Jr.
Thomas D. Penning
Ish K. Khanna
Xiangdong Xu
Richard M. Weier
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G. D. Searle & Co.
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Application filed by G. D. Searle & Co. filed Critical G. D. Searle & Co.
Publication of SK124298A3 publication Critical patent/SK124298A3/sk
Publication of SK285353B6 publication Critical patent/SK285353B6/sk

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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
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SK1242-98A 1996-04-12 1997-04-11 Substituované benzénsulfónamidy ako proliečivá COX-2 inhibítorov, farmaceutická kompozícia a spôsobich prípravy a použitia SK285353B6 (sk)

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