SK282452B6 - Kombinovaný farmaceutický prostriedok na liečbu ľudských nádorových buniek, použitie O6-benzylguanínu a temozolomidu na jeho prípravu a farmaceutický kit - Google Patents
Kombinovaný farmaceutický prostriedok na liečbu ľudských nádorových buniek, použitie O6-benzylguanínu a temozolomidu na jeho prípravu a farmaceutický kit Download PDFInfo
- Publication number
- SK282452B6 SK282452B6 SK892-95A SK89295A SK282452B6 SK 282452 B6 SK282452 B6 SK 282452B6 SK 89295 A SK89295 A SK 89295A SK 282452 B6 SK282452 B6 SK 282452B6
- Authority
- SK
- Slovakia
- Prior art keywords
- temozolomide
- atase
- benzylguanine
- treatment
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US475493A | 1993-01-14 | 1993-01-14 | |
| PCT/GB1994/000065 WO1994015615A1 (en) | 1993-01-14 | 1994-01-13 | Potentiation of temozolomide in human tumour cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK89295A3 SK89295A3 (en) | 1996-06-05 |
| SK282452B6 true SK282452B6 (sk) | 2002-02-05 |
Family
ID=21712364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK892-95A SK282452B6 (sk) | 1993-01-14 | 1994-01-13 | Kombinovaný farmaceutický prostriedok na liečbu ľudských nádorových buniek, použitie O6-benzylguanínu a temozolomidu na jeho prípravu a farmaceutický kit |
Country Status (20)
| Country | Link |
|---|---|
| EP (2) | EP0679086A1 (cs) |
| JP (1) | JPH08505615A (cs) |
| KR (1) | KR100352046B1 (cs) |
| CN (1) | CN1277541C (cs) |
| AU (1) | AU5838494A (cs) |
| CA (1) | CA2153775C (cs) |
| CZ (1) | CZ286550B6 (cs) |
| FI (1) | FI953423A7 (cs) |
| HU (1) | HUT72665A (cs) |
| IL (1) | IL108328A (cs) |
| MX (1) | MX9400434A (cs) |
| MY (1) | MY116474A (cs) |
| NO (1) | NO952781L (cs) |
| PL (1) | PL175842B1 (cs) |
| RU (1) | RU2148401C1 (cs) |
| SK (1) | SK282452B6 (cs) |
| TW (1) | TW414710B (cs) |
| UA (1) | UA29466C2 (cs) |
| WO (1) | WO1994015615A1 (cs) |
| ZA (1) | ZA94248B (cs) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5731304A (en) * | 1982-08-23 | 1998-03-24 | Cancer Research Campaign Technology | Potentiation of temozolomide in human tumour cells |
| US5942247A (en) * | 1996-07-31 | 1999-08-24 | Schering Corporation | Method for treating pediatric high grade astrocytoma including brain stem glioma |
| US5939098A (en) * | 1996-09-19 | 1999-08-17 | Schering Corporation | Cancer treatment with temozolomide |
| AU2021700A (en) * | 1998-12-07 | 2000-06-26 | Schering Corporation | Methods of using temozolomide in the treatment of cancers |
| US6251886B1 (en) | 1998-12-07 | 2001-06-26 | Schering Corporation | Methods of using temozolomide in the treatment of cancers |
| US6465448B1 (en) | 1999-08-13 | 2002-10-15 | Case Western Reserve University | Methoxyamine potentiation of temozolomide anti-cancer activity |
| US6635677B2 (en) | 1999-08-13 | 2003-10-21 | Case Western Reserve University | Methoxyamine combinations in the treatment of cancer |
| DE60321450D1 (de) * | 2002-02-22 | 2008-07-17 | Schering Corp | Pharmazeutische zubereitungen von antineoplastischen wirkstoffen, insbesondere temozolomid, verfahren zu ihrer herstellung und deren verwendung |
| ES2341767T3 (es) * | 2002-05-31 | 2010-06-28 | Transmolecular, Inc. | Quimioterapia de combinacion con clorotoxina. |
| CN100366249C (zh) * | 2002-09-29 | 2008-02-06 | 天津帝士力投资控股集团有限公司 | 一种替莫唑胺控释给药系统 |
| CN1752088A (zh) * | 2004-09-22 | 2006-03-29 | 天津市金士力药物研究开发有限公司 | 含有替莫唑胺酯的药用组合物 |
| CN100431605C (zh) * | 2005-02-03 | 2008-11-12 | 山东蓝金生物工程有限公司 | 一种抗癌药物组合物 |
| CN100402091C (zh) * | 2005-02-03 | 2008-07-16 | 山东蓝金生物工程有限公司 | 一种抗癌药物组合物 |
| CN100350975C (zh) * | 2005-02-03 | 2007-11-28 | 山东蓝金生物工程有限公司 | 抗癌药物组合物 |
| CN100350974C (zh) * | 2005-02-03 | 2007-11-28 | 山东蓝金生物工程有限公司 | 一种抗癌药物组合物 |
| GB0502573D0 (en) * | 2005-02-08 | 2005-03-16 | Topotarget As | Therapeutic compounds |
| RU2318509C2 (ru) * | 2006-02-10 | 2008-03-10 | Всеволод Иванович Киселев | Твердая лекарственная форма дииндолилметана для лечения неопластических заболеваний |
| WO2008022535A1 (fr) * | 2006-08-09 | 2008-02-28 | Tian Jin Tasly Group Co., Ltd. | Composition pharmaceutique pour traiter le gliome du cerveau, son procédé et sa préparation pharmaceutique |
| US8227439B2 (en) | 2008-05-15 | 2012-07-24 | Morphotek, Inc. | Treatment of metastatic tumors |
| JP5858932B2 (ja) | 2010-02-04 | 2016-02-10 | モルフォテック， インコーポレイテッド | クロロトキシンポリペプチドおよびコンジュゲートならびにその使用 |
| ES2601182T3 (es) | 2010-05-11 | 2017-02-14 | Fred Hutchinson Cancer Research Center | Variantes de clorotoxina, conjugados y métodos para su utilización |
| CN103169664B (zh) * | 2011-12-25 | 2015-04-22 | 复旦大学 | 一种rgd肽修饰的双层载药纳米粒及其制备方法 |
| US20150316536A1 (en) | 2012-12-10 | 2015-11-05 | Fred Hutchinson Cancer Research Center | Methods for screening |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| US12048732B2 (en) | 2016-04-15 | 2024-07-30 | Blaze Bioscience, Inc. | Methods of treating breast cancer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5352669A (en) * | 1990-03-13 | 1994-10-04 | The Of The United States Of America As Represented By The Department Of Health And Human Services | O6 -benzylated guanine, guanosine and 2'-deoxyguanosine compounds possessing O6 -alkylguanine-DNA alkyltransferase depleting activity |
-
1994
- 1994-01-13 SK SK892-95A patent/SK282452B6/sk unknown
- 1994-01-13 WO PCT/GB1994/000065 patent/WO1994015615A1/en not_active Ceased
- 1994-01-13 PL PL94309915A patent/PL175842B1/pl not_active IP Right Cessation
- 1994-01-13 CN CNB941911756A patent/CN1277541C/zh not_active Expired - Fee Related
- 1994-01-13 TW TW083100235A patent/TW414710B/zh not_active IP Right Cessation
- 1994-01-13 JP JP6515840A patent/JPH08505615A/ja active Pending
- 1994-01-13 CA CA002153775A patent/CA2153775C/en not_active Expired - Fee Related
- 1994-01-13 IL IL108328A patent/IL108328A/en not_active IP Right Cessation
- 1994-01-13 EP EP94904249A patent/EP0679086A1/en not_active Ceased
- 1994-01-13 ZA ZA94248A patent/ZA94248B/xx unknown
- 1994-01-13 EP EP98119295A patent/EP0922458A1/en not_active Withdrawn
- 1994-01-13 HU HU9502117A patent/HUT72665A/hu unknown
- 1994-01-13 MX MX9400434A patent/MX9400434A/es not_active IP Right Cessation
- 1994-01-13 AU AU58384/94A patent/AU5838494A/en not_active Abandoned
- 1994-01-13 RU RU95122792A patent/RU2148401C1/ru not_active IP Right Cessation
- 1994-01-13 UA UA95083801A patent/UA29466C2/uk unknown
- 1994-01-13 FI FI953423A patent/FI953423A7/fi not_active Application Discontinuation
- 1994-01-13 KR KR1019950702892A patent/KR100352046B1/ko not_active Expired - Fee Related
- 1994-01-13 CZ CZ19951797A patent/CZ286550B6/cs not_active IP Right Cessation
- 1994-01-13 MY MYPI94000083A patent/MY116474A/en unknown
-
1995
- 1995-07-13 NO NO952781A patent/NO952781L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ179795A3 (en) | 1996-04-17 |
| PL309915A1 (en) | 1995-11-13 |
| CN1277541C (zh) | 2006-10-04 |
| KR100352046B1 (ko) | 2003-09-03 |
| MX9400434A (es) | 1994-07-29 |
| EP0922458A1 (en) | 1999-06-16 |
| SK89295A3 (en) | 1996-06-05 |
| CZ286550B6 (cs) | 2000-05-17 |
| TW414710B (en) | 2000-12-11 |
| CA2153775C (en) | 2000-11-14 |
| WO1994015615A1 (en) | 1994-07-21 |
| CA2153775A1 (en) | 1994-07-21 |
| IL108328A (en) | 2010-05-31 |
| ZA94248B (en) | 1994-07-13 |
| UA29466C2 (uk) | 2000-11-15 |
| FI953423A0 (fi) | 1995-07-13 |
| JPH08505615A (ja) | 1996-06-18 |
| RU2148401C1 (ru) | 2000-05-10 |
| MY116474A (en) | 2004-02-28 |
| FI953423L (fi) | 1995-08-23 |
| AU5838494A (en) | 1994-08-15 |
| PL175842B1 (pl) | 1999-02-26 |
| KR960700063A (ko) | 1996-01-19 |
| HUT72665A (en) | 1996-05-28 |
| FI953423A7 (fi) | 1995-08-23 |
| IL108328A0 (en) | 1994-04-12 |
| HU9502117D0 (en) | 1995-09-28 |
| NO952781L (no) | 1995-09-13 |
| CN1117711A (zh) | 1996-02-28 |
| NO952781D0 (no) | 1995-07-13 |
| EP0679086A1 (en) | 1995-11-02 |
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