SK280786B6 - Deriváty pyridazinónu, spôsob ich prípravy, bronch - Google Patents

Deriváty pyridazinónu, spôsob ich prípravy, bronch Download PDF

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Publication number
SK280786B6
SK280786B6 SK1624-95A SK162495A SK280786B6 SK 280786 B6 SK280786 B6 SK 280786B6 SK 162495 A SK162495 A SK 162495A SK 280786 B6 SK280786 B6 SK 280786B6
Authority
SK
Slovakia
Prior art keywords
ome
alkyl
group
hydrogen
optionally substituted
Prior art date
Application number
SK1624-95A
Other languages
English (en)
Slovak (sk)
Other versions
SK162495A3 (en
Inventor
Keizo Tanikawa
Akira Saito
Mitsuaki Hirotsuka
Ken-Ichi Shikada
Original Assignee
Nisan Chemical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisan Chemical Industries Ltd. filed Critical Nisan Chemical Industries Ltd.
Publication of SK162495A3 publication Critical patent/SK162495A3/sk
Publication of SK280786B6 publication Critical patent/SK280786B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22Nitrogen and oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1624-95A 1993-06-29 1994-06-24 Deriváty pyridazinónu, spôsob ich prípravy, bronch SK280786B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15919493 1993-06-29
JP11272194 1994-05-26
PCT/JP1994/001015 WO1995001343A1 (en) 1993-06-29 1994-06-24 Pyridazinone derivatives with pharmaceutical activity

Publications (2)

Publication Number Publication Date
SK162495A3 SK162495A3 (en) 1996-11-06
SK280786B6 true SK280786B6 (sk) 2000-07-11

Family

ID=26451823

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1624-95A SK280786B6 (sk) 1993-06-29 1994-06-24 Deriváty pyridazinónu, spôsob ich prípravy, bronch

Country Status (22)

Country Link
US (2) US5728702A (hu)
EP (1) EP0706517B1 (hu)
KR (1) KR100255416B1 (hu)
CN (1) CN1044906C (hu)
AT (1) ATE172454T1 (hu)
AU (1) AU676341B2 (hu)
CA (1) CA2166326C (hu)
CZ (1) CZ289231B6 (hu)
DE (1) DE69414112T2 (hu)
DK (1) DK0706517T3 (hu)
ES (1) ES2124413T3 (hu)
FI (1) FI113963B (hu)
HU (1) HU221009B1 (hu)
IL (1) IL110040A (hu)
NO (1) NO306675B1 (hu)
NZ (1) NZ267510A (hu)
RO (1) RO114791B1 (hu)
RU (1) RU2138486C1 (hu)
SK (1) SK280786B6 (hu)
TW (1) TW408114B (hu)
UA (1) UA34481C2 (hu)
WO (1) WO1995001343A1 (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100318653B1 (ko) * 1994-01-25 2002-04-22 도쿠시마 히데이치 피리다지논유도체
DE4430755A1 (de) * 1994-08-30 1996-03-07 Boehringer Mannheim Gmbh Neue Phosphanoxide, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US6207665B1 (en) 1997-06-12 2001-03-27 Schering Aktiengesellschaft Piperazine derivatives and their use as anti-inflammatory agents
JP2002509919A (ja) * 1998-03-31 2002-04-02 日産化学工業株式会社 ピリダジノン化合物塩酸塩及びその製造法
EP1229029B1 (en) 1999-11-11 2006-06-21 Nissan Chemical Industries, Ltd. Process for producing benzylamine compound
DE60235249D1 (de) 2001-10-22 2010-03-18 Pfizer Prod Inc Piperazinderivate mit ccr1-rezeptor-antagonistischer wirkung
US20060080140A1 (en) * 2004-02-09 2006-04-13 Epic Systems Corporation System and method for providing a clinical summary of patient information in various health care settings
WO2010099388A1 (en) * 2009-02-27 2010-09-02 Indigo Pharmaceuticals Combinational use of a pde3 inhibitor and other agents
CN116768868B (zh) * 2023-08-15 2023-12-08 云南省药物研究所 一种哒嗪酮硫代衍生物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0186817B1 (en) * 1984-12-10 1989-08-02 Nissan Chemical Industries Ltd. 3(2h)pyridazinone, process for its preparation and anti-allergic agent containing it
JPH0641454B2 (ja) * 1985-02-27 1994-06-01 日産化学工業株式会社 ピリダジノン誘導体
US4892947A (en) * 1985-04-27 1990-01-09 Nissan Chemical Industries Ltd. 3(2H)Pyridazinone, process for its preparation and anti-allergic agent containing it
US4978665A (en) * 1987-01-20 1990-12-18 Nissan Chemical Industries Ltd. 3(2H)pyridazinone, and antagonistic agent against SRS-A containing it
JPH02256668A (ja) * 1988-12-20 1990-10-17 Nissan Chem Ind Ltd ピリダジノン誘導体
KR970002876B1 (ko) * 1990-04-25 1997-03-12 닛산가가꾸고오교 가부시끼가이샤 피리다지논 유도체
KR100318653B1 (ko) * 1994-01-25 2002-04-22 도쿠시마 히데이치 피리다지논유도체

Also Published As

Publication number Publication date
FI113963B (fi) 2004-07-15
IL110040A0 (en) 1994-10-07
NO306675B1 (no) 1999-12-06
CN1126470A (zh) 1996-07-10
NO955328L (no) 1996-02-28
ATE172454T1 (de) 1998-11-15
WO1995001343A1 (en) 1995-01-12
SK162495A3 (en) 1996-11-06
US5929074A (en) 1999-07-27
CN1044906C (zh) 1999-09-01
NZ267510A (en) 1996-10-28
CA2166326C (en) 2005-02-01
NO955328D0 (no) 1995-12-28
HU221009B1 (hu) 2002-07-29
US5728702A (en) 1998-03-17
DE69414112T2 (de) 1999-03-11
EP0706517A1 (en) 1996-04-17
CZ329995A3 (en) 1996-04-17
FI956300A0 (fi) 1995-12-28
HU9503807D0 (en) 1996-02-28
TW408114B (en) 2000-10-11
FI956300A (fi) 1995-12-28
ES2124413T3 (es) 1999-02-01
DK0706517T3 (da) 1999-06-28
IL110040A (en) 2000-07-16
EP0706517B1 (en) 1998-10-21
RU2138486C1 (ru) 1999-09-27
CZ289231B6 (cs) 2001-12-12
UA34481C2 (uk) 2001-03-15
KR960703401A (ko) 1996-08-17
AU6983394A (en) 1995-01-24
RO114791B1 (ro) 1999-07-30
KR100255416B1 (ko) 2000-05-01
AU676341B2 (en) 1997-03-06
HUT73483A (en) 1996-08-28
DE69414112D1 (de) 1998-11-26
CA2166326A1 (en) 1995-01-12

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