SK15282001A3 - Perorálny farmaceutický prípravok na aplikáciu do ilea, obsahujúci inhibítor transportu žlčových kyselín - Google Patents
Perorálny farmaceutický prípravok na aplikáciu do ilea, obsahujúci inhibítor transportu žlčových kyselín Download PDFInfo
- Publication number
- SK15282001A3 SK15282001A3 SK1528-2001A SK15282001A SK15282001A3 SK 15282001 A3 SK15282001 A3 SK 15282001A3 SK 15282001 A SK15282001 A SK 15282001A SK 15282001 A3 SK15282001 A3 SK 15282001A3
- Authority
- SK
- Slovakia
- Prior art keywords
- ibat inhibitor
- ileum
- ibat
- composition
- bile acid
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9901387A SE9901387D0 (sv) | 1999-04-19 | 1999-04-19 | New pharmaceutical foromaulations |
PCT/SE2000/000755 WO2000062810A1 (en) | 1999-04-19 | 2000-04-19 | An oral formulation for ileum administering comprising an inhibitor compound of the ileal bile acid transport |
Publications (1)
Publication Number | Publication Date |
---|---|
SK15282001A3 true SK15282001A3 (sk) | 2002-04-04 |
Family
ID=20415263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK1528-2001A SK15282001A3 (sk) | 1999-04-19 | 2000-04-19 | Perorálny farmaceutický prípravok na aplikáciu do ilea, obsahujúci inhibítor transportu žlčových kyselín |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP1173205B1 (de) |
JP (1) | JP2002542208A (de) |
KR (1) | KR20010108516A (de) |
CN (1) | CN1348384A (de) |
AT (1) | ATE296641T1 (de) |
AU (1) | AU767425B2 (de) |
BR (1) | BR0009835A (de) |
CA (1) | CA2379105A1 (de) |
CZ (1) | CZ20013743A3 (de) |
DE (1) | DE60020551T2 (de) |
DK (1) | DK1173205T3 (de) |
EE (1) | EE04607B1 (de) |
ES (1) | ES2241603T3 (de) |
HK (1) | HK1042850A1 (de) |
HU (1) | HUP0200793A3 (de) |
IL (1) | IL145871A0 (de) |
IS (1) | IS2161B (de) |
NO (1) | NO20015063L (de) |
NZ (1) | NZ514264A (de) |
PL (1) | PL351186A1 (de) |
PT (1) | PT1173205E (de) |
SE (1) | SE9901387D0 (de) |
SI (1) | SI1173205T1 (de) |
SK (1) | SK15282001A3 (de) |
TR (1) | TR200103033T2 (de) |
WO (1) | WO2000062810A1 (de) |
ZA (1) | ZA200108539B (de) |
Families Citing this family (69)
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SE0000772D0 (sv) | 2000-03-08 | 2000-03-08 | Astrazeneca Ab | Chemical compounds |
EG26979A (en) | 2000-12-21 | 2015-03-01 | Astrazeneca Ab | Chemical compounds |
HU229291B1 (en) * | 2001-01-31 | 2013-10-28 | Evonik Roehm Gmbh | Multi-particulate form of medicament, comprising at least two differently coated forms of pellet |
GB0121337D0 (en) | 2001-09-04 | 2001-10-24 | Astrazeneca Ab | Chemical compounds |
GB0121622D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
GB0121621D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
MY131995A (en) | 2001-09-08 | 2007-09-28 | Astrazeneca Ab | Benzothiazepine and benzothiadiazepine derivatives with illeal bile acid transport (ibat) inhibitory activity for the treatment hyperlipidaemia |
GB0209467D0 (en) | 2002-04-25 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
GB0213669D0 (en) | 2002-06-14 | 2002-07-24 | Astrazeneca Ab | Chemical compounds |
GB0216321D0 (en) * | 2002-07-13 | 2002-08-21 | Astrazeneca Ab | Therapeutic treatment |
GB0304194D0 (en) | 2003-02-25 | 2003-03-26 | Astrazeneca Ab | Chemical compounds |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
CA2724384A1 (en) | 2008-05-15 | 2009-11-19 | Transmolecular, Inc. | Treatment of metastatic tumors |
US9339480B2 (en) | 2008-11-26 | 2016-05-17 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of obesity and diabetes |
CN102316889B (zh) | 2008-11-26 | 2014-11-26 | 萨蒂奥根制药公司 | 组合物及使用方法 |
GB0900350D0 (en) * | 2009-01-09 | 2009-02-11 | Cambridge Entpr Ltd | Formulations of viable bacteria for oral delivery |
US9018347B2 (en) | 2010-02-04 | 2015-04-28 | Morphotek, Inc. | Chlorotoxin polypeptides and conjugates and uses thereof |
ES2811065T3 (es) | 2010-05-11 | 2021-03-10 | Hutchinson Fred Cancer Res | Variantes de clorotoxina, conjugados y métodos para su utilización |
EP3593802A3 (de) | 2010-05-26 | 2020-03-25 | Satiogen Pharmaceuticals, Inc. | Gallensäurerückflusshemmer zur behandlung von diabetes, adipositas und entzündlichen magen-darm-erkrankungen |
US20130225511A1 (en) | 2010-11-04 | 2013-08-29 | Per-Göran Gillberg | Ibat inhibitors for the treatment of liver diseases |
RU2619215C2 (ru) * | 2010-11-08 | 2017-05-12 | Альбирео Аб | Фармацевтическая комбинация, включающая ibat-ингибитор и связующее желчной кислоты |
MX369466B (es) | 2011-10-28 | 2019-11-08 | Lumena Pharmaceuticals Inc | Inhibidores de la recirculación de ácidos biliares para el tratamiento de enfermedades hepáticas colestásicas pediátricas. |
JP6217939B2 (ja) * | 2011-10-28 | 2017-10-25 | ルメナ ファーマシューティカルズ エルエルシー | 高胆汁血症および胆汁うっ滞性肝疾患の処置のための胆汁酸再利用阻害剤 |
US10156559B2 (en) | 2012-12-10 | 2018-12-18 | Fred Hutchinson Cancer Research Center | Lipocalin fusion partners |
JO3301B1 (ar) | 2013-04-26 | 2018-09-16 | Albireo Ab | تعديلات بلورية على إيلوبيكسيبات |
US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
KR20220082931A (ko) | 2014-06-25 | 2022-06-17 | 이에이 파마 가부시키가이샤 | 고형 제제 및 그의 착색 방지 또는 착색 감소 방법 |
EP3012252A1 (de) | 2014-10-24 | 2016-04-27 | Ferring BV | Kristalline Form von elobixibat |
CN105362244A (zh) * | 2015-11-26 | 2016-03-02 | 青岛海之源智能技术有限公司 | 考来烯胺缓释片及制备方法 |
US10441604B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Cholestyramine pellets and methods for preparation thereof |
US10441605B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Oral cholestyramine formulation and use thereof |
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US10786529B2 (en) | 2016-02-09 | 2020-09-29 | Albireo Ab | Oral cholestyramine formulation and use thereof |
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US12048732B2 (en) | 2016-04-15 | 2024-07-30 | Blaze Bioscience, Inc. | Methods of treating breast cancer |
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US10793534B2 (en) | 2018-06-05 | 2020-10-06 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
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US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
US11549878B2 (en) | 2018-08-09 | 2023-01-10 | Albireo Ab | In vitro method for determining the adsorbing capacity of an insoluble adsorbant |
US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
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US10975045B2 (en) | 2019-02-06 | 2021-04-13 | Aibireo AB | Benzothiazepine compounds and their use as bile acid modulators |
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US10941127B2 (en) | 2019-02-06 | 2021-03-09 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
KR20210137467A (ko) | 2019-02-12 | 2021-11-17 | 미룸 파마슈티컬스, 인크. | 담즙 염 유출 펌프 결핍을 갖는 환자에서 asbti에 대한 유전자형 및 용량-의존성 반응 |
JP2022544239A (ja) | 2019-08-12 | 2022-10-17 | マサチューセッツ インスティテュート オブ テクノロジー | 治療薬の投与のための物品及び方法 |
US11014898B1 (en) | 2020-12-04 | 2021-05-25 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
CN114761018A (zh) | 2019-12-04 | 2022-07-15 | 阿尔比里奥公司 | 苯并硫杂二氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
TW202134221A (zh) | 2019-12-04 | 2021-09-16 | 瑞典商艾爾比瑞歐公司 | 苯并噻二氮呯化合物及其作為膽酸調節劑之用途 |
FI4069360T3 (fi) | 2019-12-04 | 2024-02-20 | Albireo Ab | Bentsotia(di)atsepiinin yhdisteet ja niiden käyttö sappihapon modulaattoreina |
WO2021110883A1 (en) | 2019-12-04 | 2021-06-10 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
AR120683A1 (es) | 2019-12-04 | 2022-03-09 | Albireo Ab | Compuestos de benzoti(di)azepina y su uso como ácido biliar |
JP2023504643A (ja) | 2019-12-04 | 2023-02-06 | アルビレオ・アクチボラグ | ベンゾチア(ジ)アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
WO2021110887A1 (en) | 2019-12-04 | 2021-06-10 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
WO2021110886A1 (en) | 2019-12-04 | 2021-06-10 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
ES2972045T3 (es) | 2019-12-04 | 2024-06-10 | Albireo Ab | Compuestos de benzotia(di)azepina y su uso como moduladores del ácido biliar |
WO2022029101A1 (en) | 2020-08-03 | 2022-02-10 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
CA3186857A1 (en) | 2020-08-03 | 2022-02-10 | Per-Goran Gillberg | Benzothia(di)azepine compounds and their use as bile acid modulators |
CA3196488A1 (en) | 2020-11-12 | 2022-05-19 | Albireo Ab | Odevixibat for treating progressive familial intrahepatic cholestasis (pfic) |
AU2021390172A1 (en) | 2020-12-04 | 2023-06-22 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
TW202313579A (zh) | 2021-06-03 | 2023-04-01 | 瑞典商艾爾比瑞歐公司 | 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途 |
US20230338392A1 (en) | 2022-04-22 | 2023-10-26 | Albireo Ab | Subcutaneous administration of an asbt inhibitor |
CN119343140A (zh) | 2022-06-09 | 2025-01-21 | 阿尔比里奥公司 | 治疗肝炎 |
AU2023304672A1 (en) | 2022-07-05 | 2025-01-02 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
US20240207286A1 (en) | 2022-12-09 | 2024-06-27 | Albireo Ab | Asbt inhibitors in the treatment of renal diseases |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA941003B (en) * | 1993-02-15 | 1995-08-14 | Wellcome Found | Hypolipidaemic compounds |
TW289020B (de) * | 1993-05-08 | 1996-10-21 | Hoechst Sktiengesellschaft | |
JPH07223970A (ja) * | 1994-02-10 | 1995-08-22 | Tanabe Seiyaku Co Ltd | 消化管内適所放出製剤 |
-
1999
- 1999-04-19 SE SE9901387A patent/SE9901387D0/xx unknown
-
2000
- 2000-04-19 CA CA002379105A patent/CA2379105A1/en not_active Abandoned
- 2000-04-19 WO PCT/SE2000/000755 patent/WO2000062810A1/en not_active Application Discontinuation
- 2000-04-19 EE EEP200100545A patent/EE04607B1/xx not_active IP Right Cessation
- 2000-04-19 AU AU46335/00A patent/AU767425B2/en not_active Ceased
- 2000-04-19 PL PL00351186A patent/PL351186A1/xx not_active Application Discontinuation
- 2000-04-19 ES ES00928046T patent/ES2241603T3/es not_active Expired - Lifetime
- 2000-04-19 JP JP2000611946A patent/JP2002542208A/ja active Pending
- 2000-04-19 SI SI200030695T patent/SI1173205T1/xx unknown
- 2000-04-19 SK SK1528-2001A patent/SK15282001A3/sk not_active Application Discontinuation
- 2000-04-19 NZ NZ514264A patent/NZ514264A/en unknown
- 2000-04-19 TR TR2001/03033T patent/TR200103033T2/xx unknown
- 2000-04-19 HU HU0200793A patent/HUP0200793A3/hu unknown
- 2000-04-19 EP EP00928046A patent/EP1173205B1/de not_active Expired - Lifetime
- 2000-04-19 BR BR0009835-3A patent/BR0009835A/pt not_active IP Right Cessation
- 2000-04-19 PT PT00928046T patent/PT1173205E/pt unknown
- 2000-04-19 DE DE60020551T patent/DE60020551T2/de not_active Expired - Fee Related
- 2000-04-19 CZ CZ20013743A patent/CZ20013743A3/cs unknown
- 2000-04-19 AT AT00928046T patent/ATE296641T1/de not_active IP Right Cessation
- 2000-04-19 CN CN00806493A patent/CN1348384A/zh active Pending
- 2000-04-19 IL IL14587100A patent/IL145871A0/xx unknown
- 2000-04-19 DK DK00928046T patent/DK1173205T3/da active
- 2000-04-19 KR KR1020017013297A patent/KR20010108516A/ko not_active Application Discontinuation
-
2001
- 2001-10-16 IS IS6109A patent/IS2161B/is unknown
- 2001-10-17 ZA ZA200108539A patent/ZA200108539B/en unknown
- 2001-10-18 NO NO20015063A patent/NO20015063L/no not_active Application Discontinuation
-
2002
- 2002-06-12 HK HK02104408A patent/HK1042850A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SI1173205T1 (en) | 2005-10-31 |
IS2161B (is) | 2006-11-15 |
NZ514264A (en) | 2003-10-31 |
DE60020551T2 (de) | 2006-03-23 |
DE60020551D1 (de) | 2005-07-07 |
WO2000062810A1 (en) | 2000-10-26 |
NO20015063D0 (no) | 2001-10-18 |
IS6109A (is) | 2001-10-16 |
EE04607B1 (et) | 2006-04-17 |
KR20010108516A (ko) | 2001-12-07 |
EE200100545A (et) | 2003-02-17 |
AU4633500A (en) | 2000-11-02 |
CN1348384A (zh) | 2002-05-08 |
HK1042850A1 (en) | 2002-08-30 |
PT1173205E (pt) | 2005-10-31 |
SE9901387D0 (sv) | 1999-04-19 |
DK1173205T3 (da) | 2005-08-08 |
HUP0200793A2 (hu) | 2002-07-29 |
JP2002542208A (ja) | 2002-12-10 |
TR200103033T2 (tr) | 2002-03-21 |
AU767425B2 (en) | 2003-11-13 |
ATE296641T1 (de) | 2005-06-15 |
ZA200108539B (en) | 2003-01-17 |
BR0009835A (pt) | 2002-01-08 |
CZ20013743A3 (cs) | 2002-01-16 |
EP1173205B1 (de) | 2005-06-01 |
HUP0200793A3 (en) | 2004-07-28 |
EP1173205A1 (de) | 2002-01-23 |
ES2241603T3 (es) | 2005-11-01 |
IL145871A0 (en) | 2002-07-25 |
PL351186A1 (en) | 2003-03-24 |
NO20015063L (no) | 2001-10-18 |
CA2379105A1 (en) | 2000-10-26 |
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