US7855279B2
(en)
|
2005-09-27 |
2010-12-21 |
Amunix Operating, Inc. |
Unstructured recombinant polymers and uses thereof
|
US7846445B2
(en)
|
2005-09-27 |
2010-12-07 |
Amunix Operating, Inc. |
Methods for production of unstructured recombinant polymers and uses thereof
|
WO2007073486A2
(en)
|
2005-12-20 |
2007-06-28 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
US20130172274A1
(en)
|
2005-12-20 |
2013-07-04 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
US8841255B2
(en)
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
ES2385114T3
(en)
|
2007-03-30 |
2012-07-18 |
Ambrx, Inc. |
Modified FGF-21 polypeptides and their uses
|
US8563521B2
(en)
|
2007-06-21 |
2013-10-22 |
Technische Universitat Munchen |
Biological active proteins having increased in vivo and/or in vitro stability
|
JP2010536341A
(en)
|
2007-08-15 |
2010-12-02 |
アムニクス, インコーポレイテッド |
Compositions and methods for altering properties of biologically active polypeptides
|
AU2009246142A1
(en)
|
2008-05-15 |
2009-11-19 |
Transmolecular, Inc. |
Treatment of metastatic tumors
|
CN102131516B
(en)
|
2008-06-27 |
2016-03-16 |
杜克大学 |
Comprise the therapeutic agent of elastin-like peptides
|
NZ593833A
(en)
|
2009-02-03 |
2013-10-25 |
Amunix Operating Inc |
Extended recombinant polypeptides and compositions comprising same
|
US8703717B2
(en)
|
2009-02-03 |
2014-04-22 |
Amunix Operating Inc. |
Growth hormone polypeptides and methods of making and using same
|
US8680050B2
(en)
|
2009-02-03 |
2014-03-25 |
Amunix Operating Inc. |
Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
|
US8957021B2
(en)
*
|
2009-02-03 |
2015-02-17 |
Amunix Operating Inc. |
Glucose-regulating polypeptides and methods of making and using same
|
CN106916229A
(en)
*
|
2009-06-08 |
2017-07-04 |
阿穆尼克斯运营公司 |
Growth hormone polypeptides and its preparation and application
|
US9849188B2
(en)
|
2009-06-08 |
2017-12-26 |
Amunix Operating Inc. |
Growth hormone polypeptides and methods of making and using same
|
EP3222287A1
(en)
*
|
2009-08-24 |
2017-09-27 |
Amunix Operating Inc. |
Coagulation factor ix compositions and methods of making and using same
|
WO2011075185A1
(en)
|
2009-12-18 |
2011-06-23 |
Oligasis |
Targeted drug phosphorylcholine polymer conjugates
|
LT2531206T
(en)
|
2010-02-04 |
2017-09-25 |
Morphotek, Inc. |
Chlorotoxin polypeptides and conjugates and uses thereof
|
US8557961B2
(en)
|
2010-04-02 |
2013-10-15 |
Amunix Operating Inc. |
Alpha 1-antitrypsin compositions and methods of making and using same
|
WO2011123813A2
(en)
*
|
2010-04-02 |
2011-10-06 |
Amunix Operating Inc. |
Binding fusion proteins, binding fusion protein-drug conjugates, xten-drug conjugates and methods of making and using same
|
AR081361A1
(en)
|
2010-04-30 |
2012-08-29 |
Molecular Partners Ag |
MODIFIED UNION PROTEINS THAT INHIBIT THE RECEPTOR INTERACTION OF THE VASCULAR ENDOTELIAL GROWTH FACTOR FROM GLICOPROTEIN TO VEGF-A
|
ES2811065T3
(en)
|
2010-05-11 |
2021-03-10 |
Hutchinson Fred Cancer Res |
Chlorotoxin variants, conjugates and methods for their use
|
SI2571510T1
(en)
|
2010-05-21 |
2019-02-28 |
Xl-Protein Gmbh |
Biosynthetic proline/alanine random coil polypeptides and their uses
|
BR112012029611A2
(en)
|
2010-05-21 |
2017-07-25 |
Merrimack Pharmaceuticals Inc |
bispecific fusion protein, pharmaceutical composition, method of treating tissue damage in an individual, method of promoting tissue regeneration or survival in an individual, and nucleic acid molecule
|
CA2802635A1
(en)
|
2010-06-18 |
2011-12-22 |
Xiberscience Gmbh |
Peptides as active agents to stabilize biologic barriers
|
CA2806438C
(en)
|
2010-07-29 |
2021-04-13 |
Eleven Biotherapeutics, Inc. |
Chimeric il-1 receptor type i agonists and antagonists
|
EP2643349B1
(en)
|
2010-11-26 |
2019-09-04 |
Molecular Partners AG |
Designed repeat proteins binding to serum albumin
|
IL210093A0
(en)
|
2010-12-19 |
2011-06-30 |
David Helman |
Membrane bound reporter molecules and their use in cell sorting
|
WO2012103240A2
(en)
|
2011-01-25 |
2012-08-02 |
Eleven Biotherapeutics, Inc. |
Receptor binding agents
|
EP3527218A1
(en)
|
2011-06-10 |
2019-08-21 |
Bioverativ Therapeutics Inc. |
Pro-coagulant compounds and methods of use thereof
|
PT3513804T
(en)
|
2011-07-08 |
2022-06-02 |
Bioverativ Therapeutics Inc |
Factor viii chimeric and hybrid polypeptides, and methods of use thereof
|
WO2013016454A1
(en)
|
2011-07-25 |
2013-01-31 |
Biogen Idec Hemophilia Inc. |
Assays to monitor bleeding disorders
|
WO2013019652A1
(en)
|
2011-07-29 |
2013-02-07 |
Eleven Biotherapeutics, Inc. |
Purified proteins
|
WO2013024049A1
(en)
*
|
2011-08-12 |
2013-02-21 |
Ascendis Pharma A/S |
Protein carrier-linked prodrugs
|
IN2014CN00989A
(en)
|
2011-08-12 |
2015-04-10 |
Ascendis Pharma As |
|
LT2804623T
(en)
|
2012-01-12 |
2019-12-10 |
Bioverativ Therapeutics Inc |
Chimeric factor viii polypeptides and uses thereof
|
US20130210747A1
(en)
|
2012-02-13 |
2013-08-15 |
University Of Southern California |
Methods and Therapeutics Comprising Ligand-Targeted ELPs
|
ES2771208T3
(en)
|
2012-02-15 |
2020-07-06 |
Bioverativ Therapeutics Inc |
Factor VIII compositions and methods of preparation and use thereof
|
DK2822577T3
(en)
|
2012-02-15 |
2019-04-01 |
Bioverativ Therapeutics Inc |
RECOMBINANT FACTOR VIII PROTEINS
|
MX366864B
(en)
|
2012-02-27 |
2019-07-26 |
Amunix Operating Inc |
Xten conjugate compositions and methods of making same.
|
EP3646880A1
(en)
|
2012-05-07 |
2020-05-06 |
Allergan, Inc. |
Method of treating amd in patients refractory to anti-vegf therapy
|
EP2863940A4
(en)
|
2012-06-08 |
2016-08-10 |
Biogen Ma Inc |
Chimeric clotting factors
|
AU2013270682A1
(en)
|
2012-06-08 |
2014-12-11 |
Biogen Ma Inc. |
Procoagulant compounds
|
WO2014001442A1
(en)
|
2012-06-28 |
2014-01-03 |
Molecular Partners Ag |
Designed ankyrin repeat proteins binding to platelet-derived growth factor
|
US10023628B2
(en)
|
2012-07-06 |
2018-07-17 |
Bioverativ Therapeutics Inc. |
Cell line expressing single chain factor VIII polypeptides and uses thereof
|
EA201792485A3
(en)
|
2012-07-11 |
2019-03-29 |
Амуникс Оперэйтинг Инк. |
COMPLEX OF FACTOR VIII WITH XTEN AND PROTEIN FACTOR VILLEBRAND VON AND ITS APPLICATION (OPTIONS)
|
WO2014026054A2
(en)
|
2012-08-10 |
2014-02-13 |
University Of Southern California |
CD20 scFv-ELPs METHODS AND THERAPEUTICS
|
US20140092376A1
(en)
*
|
2012-10-01 |
2014-04-03 |
Momentive Performance Materials, Inc. |
Container and method for in-line analysis of protein compositions
|
AU2013331000B2
(en)
|
2012-10-18 |
2018-04-19 |
Bioverativ Therapeutics Inc. |
Methods of using a fixed dose of a clotting factor
|
EP2914293A4
(en)
|
2012-10-30 |
2016-04-20 |
Biogen Ma Inc |
Methods of using fviii polypeptide
|
WO2014081849A1
(en)
|
2012-11-20 |
2014-05-30 |
Phasebio Pharmaceuticals, Inc. |
Formulations of active agents for sustained release
|
EP2738180A1
(en)
|
2012-11-30 |
2014-06-04 |
Molecular Partners AG |
Binding proteins comprising at least two binding domains against HER2.
|
EP2928913A1
(en)
|
2012-12-10 |
2015-10-14 |
Fred Hutchinson Cancer Research Center |
Lipocalin fusion partners
|
TWI617574B
(en)
|
2012-12-11 |
2018-03-11 |
梅迪繆思有限公司 |
Glucagon and glp-1 co-agonists for the treatment of obesity
|
LT3889173T
(en)
|
2013-02-15 |
2023-10-10 |
Bioverativ Therapeutics Inc. |
Optimized factor viii gene
|
JP6450364B2
(en)
|
2013-03-13 |
2019-01-09 |
セセン バイオ, インコーポレイテッド |
Chimeric cytokine formulations for ocular delivery
|
AU2014230472A1
(en)
|
2013-03-14 |
2015-10-01 |
Medimmune Limited |
Pegylated glucagon and GLP-1 co-agonists for the treatment of obesity
|
EP2968477B1
(en)
|
2013-03-15 |
2019-12-04 |
Bioverativ Therapeutics Inc. |
Factor viii polypeptide formulations
|
JP6387392B2
(en)
|
2013-03-15 |
2018-09-05 |
バイオベラティブ セラピューティクス インコーポレイテッド |
Factor IX polypeptide preparation
|
WO2015022326A1
(en)
|
2013-08-12 |
2015-02-19 |
Xiber Science Gmbh |
Peptides as active agents for treating primary graft dysfunction
|
US10548953B2
(en)
|
2013-08-14 |
2020-02-04 |
Bioverativ Therapeutics Inc. |
Factor VIII-XTEN fusions and uses thereof
|
US20160311885A1
(en)
|
2013-08-14 |
2016-10-27 |
Biogen Ma Inc. |
Recombinant factor viii proteins
|
WO2015035342A2
(en)
|
2013-09-08 |
2015-03-12 |
Oligasis Llc |
Factor viii zwitterionic polymer conjugates
|
US11559580B1
(en)
|
2013-09-17 |
2023-01-24 |
Blaze Bioscience, Inc. |
Tissue-homing peptide conjugates and methods of use thereof
|
EP3048899B1
(en)
|
2013-09-25 |
2021-09-08 |
Bioverativ Therapeutics Inc. |
On-column viral inactivation methods
|
PL3065761T3
(en)
|
2013-11-05 |
2020-05-18 |
Allergan, Inc. |
Method of treating conditions of the eye with an anti-vegf darpin
|
EP3065769A4
(en)
|
2013-11-08 |
2017-05-31 |
Biogen MA Inc. |
Procoagulant fusion compound
|
CA2929201A1
(en)
|
2013-11-11 |
2015-05-14 |
Ascendis Pharma Relaxin Division A/S |
Relaxin prodrugs
|
DE102013113156A1
(en)
|
2013-11-28 |
2015-05-28 |
Freie Universität Berlin |
A compound and method for selectively radiolabeling polypeptides by solid phase synthesis
|
EP4332839A2
(en)
|
2013-12-06 |
2024-03-06 |
Bioverativ Therapeutics Inc. |
Population pharmacokinetics tools and uses thereof
|
EP3102224B1
(en)
*
|
2013-12-20 |
2019-02-20 |
NephroGenesis, LLC. |
Apparatuses for kidney dialysis and lipocalin protein for use in the prevention or treatment of uremia by dialysis
|
IL246476B
(en)
|
2014-01-10 |
2022-06-01 |
Biogen Ma Inc |
Factor viii chimeric proteins and uses thereof
|
US9975929B2
(en)
|
2014-03-05 |
2018-05-22 |
Merz Pharma Gmbh & Co. Kgaa |
Recombinant clostridial neurotoxins with increased duration of effect
|
SG10201808249VA
(en)
|
2014-03-24 |
2018-10-30 |
Bioverativ Therapeutics Inc |
Lyophilized factor ix formulations
|
EP2937096B1
(en)
|
2014-04-23 |
2019-08-21 |
Julius-Maximilians-Universität Würzburg |
Peptides derived from RS1 which down-regulate glucose absorption after a glucose rich meal and increase insulin sensitivity
|
US9840553B2
(en)
|
2014-06-28 |
2017-12-12 |
Kodiak Sciences Inc. |
Dual PDGF/VEGF antagonists
|
WO2016004113A1
(en)
|
2014-06-30 |
2016-01-07 |
Biogen Ma Inc. |
Optimized factor ix gene
|
US9616114B1
(en)
|
2014-09-18 |
2017-04-11 |
David Gordon Bermudes |
Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
|
CR20170110A
(en)
|
2014-09-26 |
2017-05-08 |
Bayer Pharma AG |
STABILIZED DERIVATIVES OF ADRENOMEDULINE AND USE OF THE SAME
|
ES2665218T3
(en)
|
2014-09-30 |
2018-04-24 |
Thena Biotech S.r.l. |
A fusion protein, a nanoparticle composed of a plurality of monomers of said fusion protein and uses thereof
|
ES2753391T3
(en)
|
2014-10-14 |
2020-04-08 |
Halozyme Inc |
Adenosine deaminase 2 (ADA2) compositions, variants thereof and methods of use thereof
|
CN107208076A
(en)
|
2014-10-17 |
2017-09-26 |
科达制药 |
Butyrylcholine esterase amphoteric ion polymer conjugate
|
MA40835A
(en)
|
2014-10-23 |
2017-08-29 |
Biogen Ma Inc |
ANTI-GPIIB / IIIA ANTIBODIES AND THEIR USES
|
PE20170950A1
(en)
|
2014-10-24 |
2017-07-13 |
Bristol Myers Squibb Co |
MODIFIED FIBROBLAST GROWTH FACTOR 2 (FGF-21) POLYEPTIDES AND USES OF THE SAME
|
MA40861A
(en)
|
2014-10-31 |
2017-09-05 |
Biogen Ma Inc |
ANTI-GLYCOPROTEIN IIB / IIIA ANTIBODIES
|
US10722590B2
(en)
|
2014-11-21 |
2020-07-28 |
Phasebio Pharmaceuticals, Inc. |
ELP fusion proteins for controlled and sustained release
|
WO2016079302A1
(en)
|
2014-11-21 |
2016-05-26 |
Ascendis Pharma Growth Disorders Division A/S |
Long-acting growth hormone dosage forms
|
US20160168228A1
(en)
|
2014-12-10 |
2016-06-16 |
S-Aima Holding Company, Llc |
Generation of hemoglobin-based oxygen carriers using elastin-like polypeptides
|
WO2016130518A2
(en)
|
2015-02-09 |
2016-08-18 |
Phasebio Pharmaceuticals, Inc. |
Methods and compositions for treating muscle disease and disorders
|
WO2016145237A1
(en)
*
|
2015-03-11 |
2016-09-15 |
Yu Fu-Shin X |
Composition and methods to promote wound healing
|
ES2953482T3
(en)
|
2015-04-02 |
2023-11-13 |
Molecular Partners Ag |
Ankyrin repeat domains designed with binding specificity for serum albumin
|
TWI726889B
(en)
|
2015-06-10 |
2021-05-11 |
英商梅迪繆思有限公司 |
Protease-resistant lipidated peptides
|
TW201718627A
(en)
|
2015-06-11 |
2017-06-01 |
梅茲製藥有限兩合公司 |
Recombinant clostridial neurotoxin, a use thereof, and a method for generating the same, a pharmaceutical composition comprising the same and a precursor corresponding to the same, a nucleic acid sequence encoding the precursor and a method for obtaining
|
KR20180029262A
(en)
|
2015-08-03 |
2018-03-20 |
바이오버라티브 테라퓨틱스 인크. |
Factor IX fusion proteins and methods for their manufacture and use
|
EP4129327A1
(en)
|
2015-08-28 |
2023-02-08 |
Amunix Pharmaceuticals, Inc. |
Chimeric polypeptide assembly and methods of making and using the same
|
ES2863278T3
(en)
|
2015-10-02 |
2021-10-11 |
Silver Creek Pharmaceuticals Inc |
Bispecific therapeutic proteins for tissue repair
|
WO2017083491A2
(en)
*
|
2015-11-10 |
2017-05-18 |
Proteothera, Inc. |
Methods of producing and purifying matrix-binding fusion proteins by ion-exchange chromatography
|
EP3394266B1
(en)
*
|
2015-12-22 |
2021-04-14 |
XL-protein GmbH |
Nucleic acids encoding repetitive amino acid sequences rich in proline and alanine residues that have low repetitive nucleotide sequences
|
EP3397276A4
(en)
|
2015-12-30 |
2019-12-18 |
Kodiak Sciences Inc. |
Antibodies and conjugates thereof
|
WO2017118707A1
(en)
|
2016-01-08 |
2017-07-13 |
Ascendis Pharma Growth Disorders A/S |
Controlled-release cnp agonists with reduced side-effects
|
DK3400019T3
(en)
|
2016-01-08 |
2022-10-24 |
Ascendis Pharma Growth Disorders As |
CNP prodrugs with carrier attachment at the ring unit
|
NZ743487A
(en)
|
2016-01-08 |
2023-02-24 |
Ascendis Pharma Growth Disorders As |
Controlled-release cnp agonists with increased nep stability
|
CA3007976C
(en)
|
2016-01-08 |
2023-09-26 |
Ascendis Pharma Growth Disorders A/S |
Cnp prodrugs with large carrier moieties
|
EP3400022A1
(en)
|
2016-01-08 |
2018-11-14 |
Ascendis Pharma Growth Disorders A/S |
Controlled-release cnp agonists with low initial npr-b activity
|
AU2017205694B2
(en)
|
2016-01-08 |
2022-05-26 |
Ascendis Pharma Growth Disorders A/S |
Controlled-release CNP agonists with low NPR-C binding
|
ES2929347T3
(en)
*
|
2016-01-20 |
2022-11-28 |
Merz Pharma Gmbh & Co Kgaa |
Novel recombinant clostridial neurotoxins with increased duration of effect
|
AU2017214378B2
(en)
|
2016-02-01 |
2023-05-04 |
Bioverativ Therapeutics Inc. |
Optimized Factor VIII genes
|
EP3423103A1
(en)
|
2016-03-01 |
2019-01-09 |
Ascendis Pharma Bone Diseases A/S |
Pth prodrugs
|
KR102460198B1
(en)
|
2016-03-10 |
2022-10-31 |
메디뮨 리미티드 |
Glucagon and GLP-1 co-agonists for the treatment of obesity
|
AU2017260274A1
(en)
*
|
2016-05-04 |
2018-11-01 |
Navigo Proteins Gmbh |
Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker
|
KR102449167B1
(en)
|
2016-05-06 |
2022-09-28 |
파세비오 파마수티컬스 인코포레이티드 |
ELP fusion protein for controlled sustained release
|
US11896671B2
(en)
|
2016-07-13 |
2024-02-13 |
Ascendis Pharma A/S |
Conjugation method for carrier-linked prodrugs
|
JP7085535B2
(en)
|
2016-09-29 |
2022-06-16 |
アセンディス ファーマ ボーン ディジージズ エー/エス |
PTH compounds with a small peak-to-trough ratio
|
CA3037444A1
(en)
|
2016-09-29 |
2018-04-05 |
Ascendis Pharma Bone Diseases A/S |
Incremental dose finding in controlled-release pth compounds
|
LT3518960T
(en)
|
2016-09-29 |
2023-09-11 |
Ascendis Pharma Bone Diseases A/S |
Dosage regimen for a controlled-release pth compound
|
SI3518930T1
(en)
|
2016-09-29 |
2023-06-30 |
Ascendis Pharma Growth Disorders A/S |
Combination therapy with controlled-release cnp agonists
|
WO2018102743A1
(en)
|
2016-12-02 |
2018-06-07 |
Bioverativ Therapeutics Inc. |
Methods of treating hemophilic arthropathy using chimeric clotting factors
|
EP3548063A1
(en)
|
2016-12-02 |
2019-10-09 |
Bioverativ Therapeutics Inc. |
Methods of inducing immune tolerance to clotting factors
|
US11180535B1
(en)
|
2016-12-07 |
2021-11-23 |
David Gordon Bermudes |
Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
|
US11129906B1
(en)
|
2016-12-07 |
2021-09-28 |
David Gordon Bermudes |
Chimeric protein toxins for expression by therapeutic bacteria
|
MA47163A
(en)
|
2016-12-16 |
2019-11-06 |
Biogen Ma Inc |
PROTEOLYTICALLY STABILIZED ACTIVATED GROWTH DIFFERENTIATION FACTOR 11
|
MX2019009063A
(en)
|
2017-01-31 |
2019-10-21 |
Bioverativ Therapeutics Inc |
Factor ix fusion proteins and methods of making and using same.
|
EP3596115A1
(en)
|
2017-03-16 |
2020-01-22 |
Alpine Immune Sciences, Inc. |
Pd-l2 variant immunomodulatory proteins and uses thereof
|
WO2018170026A2
(en)
|
2017-03-16 |
2018-09-20 |
Alpine Immune Sciences, Inc. |
Cd80 variant immunomodulatory proteins and uses thereof
|
HRP20231382T1
(en)
|
2017-03-16 |
2024-02-16 |
Alpine Immune Sciences, Inc. |
Pd-l1 variant immunomodulatory proteins and uses thereof
|
CA3059938A1
(en)
|
2017-04-14 |
2018-10-18 |
Kodiak Sciences Inc. |
Complement factor d antagonist antibodies and conjugates thereof
|
PL3612208T3
(en)
|
2017-04-21 |
2023-07-24 |
Volution Immuno Pharmaceuticals Sa |
Coversin for the treatment of autoimmune blistering diseases
|
US10174302B1
(en)
|
2017-06-21 |
2019-01-08 |
Xl-Protein Gmbh |
Modified L-asparaginase
|
KR20200030065A
(en)
|
2017-06-21 |
2020-03-19 |
재즈 파마슈티칼즈 아일랜드 리미티드 |
Modified L-asparaginase
|
JP7224650B2
(en)
*
|
2017-06-21 |
2023-02-20 |
エクスエル‐プロテイン ゲーエムベーハー |
Conjugates of protein drugs and P/A peptides
|
EP3649143B1
(en)
|
2017-07-06 |
2022-08-31 |
Merz Pharma GmbH & Co. KGaA |
Novel recombinant botulinum neurotoxins with increased duration of effect
|
TW201920255A
(en)
|
2017-08-09 |
2019-06-01 |
美商生物化學醫療公司 |
Nucleic acid molecules and uses thereof
|
AU2018351000B2
(en)
|
2017-10-18 |
2023-11-30 |
Alpine Immune Sciences, Inc. |
Variant ICOS Ligand immunomodulatory proteins and related compositions and methods
|
PT3707261T
(en)
*
|
2017-11-06 |
2022-07-13 |
Thena Biotech S R L |
Fusion-proteins based on human ferritin and protease-cleavable peptides and their use as chemotherapeutics carriers
|
EP3483619A1
(en)
*
|
2017-11-13 |
2019-05-15 |
Technische Universität München |
Automated noninvasive determining the sex of an embryo of and the fertility of a bird's egg
|
AU2019205273B2
(en)
|
2018-01-03 |
2024-04-04 |
Alpine Immune Sciences, Inc. |
Multi-domain immunomodulatory proteins and methods of use thereof
|
BR112020015228A2
(en)
|
2018-02-01 |
2020-12-29 |
Bioverativ Therapeutics Inc. |
USE OF LENTIVIRAL VECTORS THAT EXPRESS FACTOR VIII
|
GB201804092D0
(en)
*
|
2018-03-14 |
2018-04-25 |
Imperial Innovations Ltd |
Methods and compositions
|
KR20200139730A
(en)
|
2018-03-28 |
2020-12-14 |
아센디스 파마 온콜로지 디비전 에이/에스 |
IL-2 conjugate
|
CA3093083A1
(en)
|
2018-03-28 |
2019-10-03 |
Ascendis Pharma A/S |
Conjugates
|
EP3774861A1
(en)
|
2018-03-28 |
2021-02-17 |
Bristol-Myers Squibb Company |
Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use
|
KR20210020030A
(en)
|
2018-05-18 |
2021-02-23 |
바이오버라티브 테라퓨틱스 인크. |
How to treat hemophilia A
|
AU2019270464A1
(en)
|
2018-05-18 |
2020-11-19 |
Ascendis Pharma Bone Diseases A/S |
Starting dose of PTH conjugates
|
US20210363219A1
(en)
|
2018-06-15 |
2021-11-25 |
Alpine Immune Sciences, Inc. |
Pd-1 variant immunomodulatory proteins and uses thereof
|
BR112020026512A2
(en)
|
2018-07-03 |
2021-04-06 |
Bristol-Myers Squibb Company |
FGF-21 FORMULATIONS
|
MX2021001599A
(en)
|
2018-08-09 |
2021-07-02 |
Bioverativ Therapeutics Inc |
Nucleic acid molecules and uses thereof for non-viral gene therapy.
|
EP3849588A1
(en)
|
2018-09-10 |
2021-07-21 |
Volution Immuno Pharmaceuticals SA |
Coversin for use in the treatment of rheumatic diseases
|
BR112021005907A2
(en)
|
2018-09-27 |
2021-08-10 |
Xilio Development, Inc. |
masked cytokines, nucleic acid, vector, host cell, methods for producing a masked cytokine, for treating or preventing a neoplastic disease and for treating or preventing a neoplastic inflammatory or autoimmune disease, composition, pharmaceutical composition and kit
|
CN111040021B
(en)
*
|
2018-10-12 |
2023-06-02 |
浙江道尔生物科技有限公司 |
Carrier protein for improving bioactive protein property
|
JP2022013959A
(en)
*
|
2018-11-02 |
2022-01-19 |
味の素株式会社 |
Fusion protein
|
CN111153965A
(en)
*
|
2018-11-07 |
2020-05-15 |
浙江道尔生物科技有限公司 |
Artificial recombinant protein for improving performance of active protein or polypeptide and application thereof
|
US20220025344A1
(en)
|
2018-11-26 |
2022-01-27 |
Novartis Ag |
Lpl-gpihbp1 fusion polypeptides
|
JP2022510276A
(en)
|
2018-11-30 |
2022-01-26 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
CD86 variant immunomodulatory protein and its use
|
EP3891289A2
(en)
|
2018-12-06 |
2021-10-13 |
Bioverativ Therapeutics Inc. |
Use of lentiviral vectors expressing factor ix
|
JP2022520189A
(en)
|
2019-02-11 |
2022-03-29 |
アセンディス ファーマ ボーン ディジージズ エー/エス |
Liquid pharmaceutical formulation of PTH conjugate
|
AU2020223441A1
(en)
|
2019-02-11 |
2021-07-29 |
Ascendis Pharma Growth Disorders A/S |
Dry pharmaceutical formulations of CNP conjugates
|
CN113573698A
(en)
|
2019-03-04 |
2021-10-29 |
阿森迪斯药物内分泌股份有限公司 |
Long-acting growth hormone dosage form having superior efficacy compared to daily growth hormone
|
CN114008069A
(en)
|
2019-04-17 |
2022-02-01 |
科迪亚克生物科学公司 |
Compositions of exosomes and AAV
|
GB201905810D0
(en)
|
2019-04-25 |
2019-06-05 |
Volution Immuno Pharmaceuticals Sa |
Method of treatment
|
CN114174326A
(en)
|
2019-06-18 |
2022-03-11 |
拜耳公司 |
Long-term stable adrenomedullin analogues and uses thereof
|
AU2020296297A1
(en)
|
2019-06-21 |
2021-12-16 |
Ascendis Pharma A/S |
Conjugates of heteroaromatic nitrogen-comprising compounds
|
CA3143435A1
(en)
|
2019-06-21 |
2020-12-24 |
Nicola BISEK |
Conjugates of an electron-donating nitrogen or tertiary amine comprising compounds
|
US20230065814A1
(en)
|
2019-06-21 |
2023-03-02 |
Ascendis Pharma A/S |
Conjugates of-electron-pair-donating heteroaromatic nitrogen-comprising compounds
|
US20220281939A1
(en)
|
2019-08-27 |
2022-09-08 |
Tonix Pharma Limited |
Modified tff2 polypeptides
|
WO2021058117A1
(en)
|
2019-09-27 |
2021-04-01 |
Volution Immuno Pharmaceuticals Sa |
Method of treatment of hematopoietic stem cell transplant associated thrombotic microangiopathy (hsct-tma)
|
TW202126284A
(en)
|
2019-09-30 |
2021-07-16 |
美商百歐維拉提夫治療公司 |
Lentiviral vector formulations
|
EP4041312A4
(en)
|
2019-10-10 |
2023-12-20 |
Kodiak Sciences Inc. |
Methods of treating an eye disorder
|
CN113597434B
(en)
|
2019-12-31 |
2022-07-01 |
北京质肽生物医药科技有限公司 |
Fusion proteins of GLP-1 and GDF15 and conjugates thereof
|
CN115175738A
(en)
|
2020-01-03 |
2022-10-11 |
阿森迪斯药物股份有限公司 |
Conjugates undergoing intramolecular rearrangement
|
CN115322794A
(en)
|
2020-01-11 |
2022-11-11 |
北京质肽生物医药科技有限公司 |
Conjugates of fusion proteins of GLP-1 and FGF21
|
KR20220128390A
(en)
|
2020-01-13 |
2022-09-20 |
아센디스 파마 본 디지즈 에이/에스 |
Treatment of hypoparathyroidism
|
WO2021226553A2
(en)
|
2020-05-08 |
2021-11-11 |
Alpine Immune Sciences, Inc. |
April and baff inhibitory immunomodulatory proteins with and without a t cell inhibitory protein and methods of use thereof
|
EP4161956A1
(en)
|
2020-06-03 |
2023-04-12 |
Ascendis Pharma Oncology Division A/S |
Il-2 sequences and uses thereof
|
CA3184998A1
(en)
|
2020-08-05 |
2022-02-10 |
Samuel WEISBROD |
Conjugates comprising reversible linkers and uses thereof
|
WO2022032187A1
(en)
|
2020-08-07 |
2022-02-10 |
Bristol-Myers Squibb Company |
Fgf21 combined with ccr2/5 antagonists for the treatment of fibrosis
|
IL300668A
(en)
|
2020-08-28 |
2023-04-01 |
Ascendis Pharma Oncology Div A/S |
Glycosylated il-2 proteins and uses thereof
|
TW202228784A
(en)
|
2020-09-23 |
2022-08-01 |
奧地利商艾柏力維亞生技有限公司 |
Compound for the sequestration of undesirale anti-peg antibodies in a patient
|
MX2023003540A
(en)
|
2020-09-28 |
2023-04-21 |
Ascendis Pharma Bone Diseases As |
Improvement of physical and mental well-being of patients with hypoparathyroidism.
|
JP2023545684A
(en)
|
2020-09-30 |
2023-10-31 |
ベイジン キューエル バイオファーマシューティカル カンパニー,リミテッド |
Polypeptide conjugates and methods of use
|
WO2022115597A1
(en)
|
2020-11-25 |
2022-06-02 |
Bristol-Myers Squibb Company |
Methods of treating liver diseases
|
EP4259199A1
(en)
|
2020-12-11 |
2023-10-18 |
Friedrich Miescher Institute for Biomedical Research |
Hdac6 binding proteins and their anti-viral use
|
WO2022136582A1
(en)
|
2020-12-22 |
2022-06-30 |
Xl-Protein Gmbh |
Antibodies specific for structurally disordered sequences
|
IL307192A
(en)
|
2021-04-01 |
2023-11-01 |
Ascendis Pharma As |
Use of long-acting growth hormone for treating inflammation-induced diseases
|
TW202313974A
(en)
|
2021-06-08 |
2023-04-01 |
瑞典商阿斯特捷利康公司 |
Combination therapies for treatment of liver diseases
|
CA3229668A1
(en)
|
2021-08-23 |
2023-03-02 |
Bioverativ Therapeutics Inc. |
Baculovirus expression system
|
CA3230895A1
(en)
|
2021-09-22 |
2023-03-30 |
Kennett Sprogoe |
Long-acting pth compound treatments
|
WO2023110758A1
(en)
|
2021-12-13 |
2023-06-22 |
Ascendis Pharma Growth Disorders A/S |
Effective doses of cnp conjugates
|
WO2023227505A1
(en)
|
2022-05-23 |
2023-11-30 |
Ascendis Pharma Growth Disorders A/S |
Liquid pharmaceutical formulations of cnp compounds
|
EP4342460A1
(en)
|
2022-09-21 |
2024-03-27 |
NovoArc GmbH |
Lipid nanoparticle with nucleic acid cargo
|