SG115741A1 - New 4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds, a process for their preparation and pharmaceutical compositions containing them - Google Patents

New 4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds, a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
SG115741A1
SG115741A1 SG200501360A SG200501360A SG115741A1 SG 115741 A1 SG115741 A1 SG 115741A1 SG 200501360 A SG200501360 A SG 200501360A SG 200501360 A SG200501360 A SG 200501360A SG 115741 A1 SG115741 A1 SG 115741A1
Authority
SG
Singapore
Prior art keywords
pyrrolo
pyrazine
tetrahydro
oxo
preparation
Prior art date
Application number
SG200501360A
Other languages
English (en)
Inventor
De Nanteuil Guillaume
Gloanec Philippe
Parmentier Jean-Gilles
Benoist Alain
Rupin Alain
Vallez Marie-Odile
Verbeuren Tony
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of SG115741A1 publication Critical patent/SG115741A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A47FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47JKITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
    • A47J27/00Cooking-vessels
    • A47J27/14Cooking-vessels for use in hotels, restaurants, or canteens
    • A47J27/16Cooking-vessels for use in hotels, restaurants, or canteens heated by steam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • AHUMAN NECESSITIES
    • A47FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47JKITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
    • A47J27/00Cooking-vessels
    • A47J27/12Multiple-unit cooking vessels
    • A47J27/13Tier cooking-vessels
    • AHUMAN NECESSITIES
    • A47FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47JKITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
    • A47J36/00Parts, details or accessories of cooking-vessels
    • A47J36/24Warming devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SG200501360A 2004-03-19 2005-03-04 New 4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds, a process for their preparation and pharmaceutical compositions containing them SG115741A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0402841A FR2867780B1 (fr) 2004-03-19 2004-03-19 Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
SG115741A1 true SG115741A1 (en) 2005-10-28

Family

ID=34896643

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200501360A SG115741A1 (en) 2004-03-19 2005-03-04 New 4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds, a process for their preparation and pharmaceutical compositions containing them

Country Status (31)

Country Link
US (2) US7498330B2 (de)
EP (1) EP1593682B1 (de)
JP (1) JP2005272467A (de)
KR (1) KR100741236B1 (de)
CN (1) CN1297558C (de)
AR (1) AR048277A1 (de)
AT (1) ATE377601T1 (de)
AU (1) AU2005201198B8 (de)
BR (1) BRPI0500889A (de)
CA (1) CA2500575C (de)
CY (1) CY1107157T1 (de)
DE (1) DE602005003161T2 (de)
DK (1) DK1593682T3 (de)
EA (1) EA008688B1 (de)
ES (1) ES2296104T3 (de)
FR (1) FR2867780B1 (de)
GE (1) GEP20074035B (de)
HK (1) HK1079775A1 (de)
HR (1) HRP20070518T8 (de)
MA (1) MA27547A1 (de)
MX (1) MXPA05002985A (de)
MY (1) MY136910A (de)
NO (1) NO20051367L (de)
NZ (1) NZ538935A (de)
PL (1) PL1593682T3 (de)
PT (1) PT1593682E (de)
RS (1) RS50547B (de)
SG (1) SG115741A1 (de)
SI (1) SI1593682T1 (de)
UA (1) UA83638C2 (de)
ZA (1) ZA200502316B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2867780B1 (fr) * 2004-03-19 2006-05-19 Servier Lab Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN101092372B (zh) * 2006-06-20 2011-09-21 上海药明康德新药开发有限公司 光学活性α-氨基庚二酸酯或单酯的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2701951B1 (fr) * 1993-02-24 1995-06-09 Adir Nouveaux derives peptidiques de l'acide boronique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
US6156540A (en) * 1993-12-22 2000-12-05 Human Genome Sciences, Inc. Thrombin inhibitor
IL112795A (en) * 1994-03-04 2001-01-28 Astrazeneca Ab Derivatives of peptides as antithrombotic drugs, their preparation, and pharmaceutical preparations containing them
CA2245811A1 (en) * 1996-02-22 1997-08-28 Merck & Co., Inc. Pyridinone thrombin inhibitors
UA58636C2 (uk) * 1999-06-04 2003-08-15 Мерк Енд Ко., Інк. Піразинонові інгібітори тромбіну, фармацевтична композиція, спосіб інгібування утворення тромбів у крові, спосіб лікування станів, пов'язаних із тромбоутворенням
FR2795072B1 (fr) * 1999-06-15 2001-07-27 Adir Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2818277B1 (fr) * 2000-12-14 2003-01-24 Servier Lab Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2867780B1 (fr) * 2004-03-19 2006-05-19 Servier Lab Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
DE602005003161D1 (de) 2007-12-20
AR048277A1 (es) 2006-04-12
AU2005201198B2 (en) 2010-11-11
SI1593682T1 (sl) 2008-02-29
HRP20070518T5 (en) 2008-10-31
BRPI0500889A (pt) 2005-11-01
UA83638C2 (ru) 2008-08-11
GEP20074035B (en) 2007-02-12
MXPA05002985A (es) 2005-10-06
ES2296104T3 (es) 2008-04-16
EP1593682B1 (de) 2007-11-07
EP1593682A2 (de) 2005-11-09
AU2005201198A1 (en) 2005-10-06
US20090131668A1 (en) 2009-05-21
CN1680377A (zh) 2005-10-12
US7498330B2 (en) 2009-03-03
KR20060044455A (ko) 2006-05-16
CA2500575A1 (fr) 2005-09-19
CY1107157T1 (el) 2012-10-24
EP1593682A3 (de) 2006-01-18
PL1593682T3 (pl) 2008-03-31
CA2500575C (fr) 2010-06-22
RS50547B (sr) 2010-05-07
KR100741236B1 (ko) 2007-07-19
ATE377601T1 (de) 2007-11-15
CN1297558C (zh) 2007-01-31
EA200500379A1 (ru) 2005-10-27
AU2005201198B8 (en) 2011-03-10
FR2867780B1 (fr) 2006-05-19
PT1593682E (pt) 2007-12-06
ZA200502316B (en) 2005-10-03
JP2005272467A (ja) 2005-10-06
FR2867780A1 (fr) 2005-09-23
EA008688B1 (ru) 2007-06-29
DK1593682T3 (da) 2008-03-03
NO20051367L (no) 2005-09-20
NO20051367D0 (no) 2005-03-16
HRP20070518T3 (en) 2007-12-31
NZ538935A (en) 2005-09-30
MY136910A (en) 2008-11-28
MA27547A1 (fr) 2005-10-03
HK1079775A1 (en) 2006-04-13
DE602005003161T2 (de) 2008-09-18
US20050209234A1 (en) 2005-09-22
HRP20070518T8 (en) 2008-10-31

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