SG11202105512PA - Orally active prodrug of gemcitabine - Google Patents
Orally active prodrug of gemcitabineInfo
- Publication number
- SG11202105512PA SG11202105512PA SG11202105512PA SG11202105512PA SG11202105512PA SG 11202105512P A SG11202105512P A SG 11202105512PA SG 11202105512P A SG11202105512P A SG 11202105512PA SG 11202105512P A SG11202105512P A SG 11202105512PA SG 11202105512P A SG11202105512P A SG 11202105512PA
- Authority
- SG
- Singapore
- Prior art keywords
- gemcitabine
- orally active
- active prodrug
- prodrug
- orally
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862771100P | 2018-11-25 | 2018-11-25 | |
| PCT/US2019/062747 WO2020107013A1 (en) | 2018-11-25 | 2019-11-22 | Orally active prodrug of gemcitabine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202105512PA true SG11202105512PA (en) | 2021-06-29 |
Family
ID=70774630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202105512PA SG11202105512PA (en) | 2018-11-25 | 2019-11-22 | Orally active prodrug of gemcitabine |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20220033430A1 (en) |
| EP (1) | EP3883947A4 (en) |
| JP (1) | JP2022510169A (en) |
| KR (1) | KR20210096160A (en) |
| CN (1) | CN113939525A (en) |
| AU (1) | AU2019384826A1 (en) |
| BR (1) | BR112021009988A2 (en) |
| CA (1) | CA3120941A1 (en) |
| IL (1) | IL283375A (en) |
| MX (1) | MX2021006121A (en) |
| SG (1) | SG11202105512PA (en) |
| WO (1) | WO2020107013A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202203421D0 (en) | 2022-03-11 | 2022-04-27 | Laevoroc Chemotherapy Ag | Orally active prodrug of gemcitabine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5633367A (en) * | 1995-03-24 | 1997-05-27 | Eli Lilly And Company | Process for the preparation of a 2-substituted 3,3-difluorofuran |
| DE19924818A1 (en) * | 1999-05-29 | 2000-11-30 | Bayer Ag | Substituted phenylcyclohexane carboxamides |
| US20040181051A1 (en) * | 2002-12-23 | 2004-09-16 | Richard Storer | Process for the production of 3'-nucleoside prodrugs |
| UA97245C2 (en) * | 2006-06-02 | 2012-01-25 | Меиджи Сеика Фарма Ко., Лтд. | Aminoglycoside antibiotics |
| EA201190178A1 (en) * | 2009-03-20 | 2012-06-29 | Алиос Биофарма, Инк. | REPLACED NUCLEOSIDE AND NUCLEOTIC ANALOGUES |
| WO2012040126A1 (en) * | 2010-09-22 | 2012-03-29 | Alios Biopharma, Inc. | Substituted nucleotide analogs |
| CN105288648B (en) * | 2015-10-14 | 2018-11-06 | 东南大学 | A kind of phosphatide cpd of hydrophilic medicament, its pharmaceutical composition and application |
-
2019
- 2019-11-22 EP EP19886709.5A patent/EP3883947A4/en active Pending
- 2019-11-22 JP JP2021529711A patent/JP2022510169A/en active Pending
- 2019-11-22 KR KR1020217019385A patent/KR20210096160A/en unknown
- 2019-11-22 US US17/296,403 patent/US20220033430A1/en active Pending
- 2019-11-22 SG SG11202105512PA patent/SG11202105512PA/en unknown
- 2019-11-22 WO PCT/US2019/062747 patent/WO2020107013A1/en active Application Filing
- 2019-11-22 MX MX2021006121A patent/MX2021006121A/en unknown
- 2019-11-22 AU AU2019384826A patent/AU2019384826A1/en not_active Abandoned
- 2019-11-22 BR BR112021009988-3A patent/BR112021009988A2/en not_active Application Discontinuation
- 2019-11-22 CA CA3120941A patent/CA3120941A1/en active Pending
- 2019-11-22 CN CN201980090197.3A patent/CN113939525A/en active Pending
-
2021
- 2021-05-23 IL IL283375A patent/IL283375A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20220033430A1 (en) | 2022-02-03 |
| EP3883947A4 (en) | 2022-08-24 |
| CN113939525A (en) | 2022-01-14 |
| AU2019384826A1 (en) | 2021-07-15 |
| BR112021009988A2 (en) | 2021-08-17 |
| EP3883947A1 (en) | 2021-09-29 |
| MX2021006121A (en) | 2021-10-13 |
| WO2020107013A1 (en) | 2020-05-28 |
| CA3120941A1 (en) | 2020-05-28 |
| IL283375A (en) | 2021-07-29 |
| JP2022510169A (en) | 2022-01-26 |
| KR20210096160A (en) | 2021-08-04 |
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